Eirik Sundby
Publikasjoner
2023
-
Aarhus, Thomas Ihle;
Teksum, Vilde;
Unger, Anke;
Habenberger, Peter;
Wolf, Alexander;
Eickhoff, Jan.
(2023)
Negishi Cross-Coupling in the Preparation of Benzyl Substituted Pyrrolo[2,3-d]pyrimidine Based CSF1R Inhibitors.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Aarhus, Thomas Ihle;
Bjørnstad, Frithjof Andreas;
Wolowczyk, Camilla Izabel;
Larsen, Kristin Uhlving;
Rognstad, Line;
Leithaug, Trygve.
(2023)
Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form.
Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Aarhus, Thomas Ihle;
Eickhoff, Jan;
Klebl, Bert;
Unger, Anke;
Boros, Johanna;
Choidas, Axel.
(2023)
A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Bjørnstad, Frithjof Andreas;
Sundby, Eirik;
Hoff, Bård Helge.
(2023)
Directed Lithiation of Protected 4-Chloropyrrolopyrimidine: Addition to Aldehydes and Ketones Aided by Bis(2-dimethylaminoethyl)ether.
Molecules
Vitenskapelig artikkel
-
Singleton, Amanda Holstad;
Bergum, Olaug Elisabeth Torheim;
Søgaard, Caroline Krogh;
Røst, Lisa M.;
Olsen, Cecilie Elisabeth;
Blindheim, Fredrik Heen.
(2023)
Activation of multiple stress responses in Staphylococcus aureus substantially lowers the minimal inhibitory concentration when combining two novel antibiotic drug candidates.
Frontiers in Microbiology
Vitenskapelig artikkel
2022
-
Olsen, Cecilie Elisabeth;
Blindheim, Fredrik Heen;
Søgaard, Caroline Krogh;
Røst, Lisa M.;
Singleton, Amanda;
Bergum, Olaug Elisabeth Torheim.
(2022)
Halogenated Pyrrolopyrimidines with Low MIC on Staphylococcus aureus and Synergistic Effects with an Antimicrobial Peptide.
Antibiotics
Vitenskapelig artikkel
2021
-
Blindheim, Fredrik Heen;
Thoresen Malme, Ane;
Dalhus, Bjørn;
Sundby, Eirik;
Hoff, Bård Helge.
(2021)
Synthesis and Evaluation of Fused Pyrimidines as E. coli Thymidylate Monophosphate Kinase Inhibitors.
ChemistrySelect
Vitenskapelig artikkel
-
El-Behairy, Mohammed Farrag;
Hassan, Rasha M.;
Sundby, Eirik.
(2021)
Enantioselective chromatographic separation and lipase catalyzed asymmetric resolution of biologically important chiral amines.
Separations
Vitenskapelig artikkel
-
Guttormsen, Yngve;
Moldes-Anaya, Angel;
Fjellaksel, Richard;
Oteiza, Ana;
Martin-Armas, Montserrat;
Lindemann, Marcel.
(2021)
Development of a carbon-11 labeled thienopyrimidine based radioligand for EGFR-tyrosine-kinase-inhibitor (TKI) specific PET imaging of glioblastoma.
Journal of Nuclear Medicine
Sammendrag/abstract
-
Guttormsen, Yngve;
Kranz, Mathias;
Fjellaksel, Richard;
Martin-Armas, Montserrat;
Oteiza, Ana;
Bihler, Julia.
(2021)
SP-015 - Preliminary evaluation of a novel carbon-11 labeled brain-penetrant EGFR-TKI radiotracer for brain cancer imaging.
Nuclear Medicine and Biology
Sammendrag/abstract
-
Blindheim, Fredrik Heen;
Olsen, Cecilie Elisabeth;
Søgaard, Caroline Krogh;
Otterlei, Marit;
Sundby, Eirik;
Hoff, Bård Helge.
(2021)
Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents
.
European Journal of Organic Chemistry
Vitenskapelig artikkel
2020
-
Sundby, Eirik;
Haugen, Ingrid Naterstad.
(2020)
Comparison of Students' Perceived Learning in Two Similar Lab Courses with Different Teaching Staffs.
Universal Journal of Educational Research
Vitenskapelig artikkel
2019
-
Reiersølmoen, Ann Christin;
Aarhus, Thomas Ihle;
Eckelt, Sarah;
Nørsett, Kristin Gabestad;
Sundby, Eirik;
Hoff, Bård Helge.
(2019)
Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines.
Bioorganic chemistry (Print)
Vitenskapelig artikkel
2018
-
Reiersølmoen, Ann Christin;
Han, Jin;
Sundby, Eirik;
Hoff, Bård Helge.
(2018)
Identification of fused pyrimidines as interleukin 17 secretion inhibitors.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
2017
-
Petrovic, Voin;
Olaisen, Camilla;
Sharma, Animesh;
Nepal, Anala;
Bugge, Steffen;
Sundby, Eirik.
(2017)
Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel.
Data in Brief
Vitenskapelig artikkel
-
Hoff, Bård Helge;
Sundby, Eirik.
(2017)
Is literature data useful for identifying enzyme catalysts for new substrates? A case study on reduction of 1-aryl-2-alkanoates.
Bioorganic chemistry (Print)
Vitenskapelig artikkel
-
Petrovic, Voin;
Olaisen, Camilla;
Sharma, Animesh;
Nepal, Anala;
Bugge, Steffen;
Sundby, Eirik.
(2017)
On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay.
Analytical Biochemistry
Vitenskapelig artikkel
-
Willumsen, Fredrik Bysting;
Bugge, Steffen;
Sundby, Eirik;
Hoff, Bård Helge.
(2017)
Investigation of Heck coupling on 6-bromo[2,3-d]thienopyrimidines for construction of new EGFR inhibitor lead structures.
RSC Advances
Vitenskapelig artikkel
2016
-
El-Behairy, Mohammed Farrag;
Sundby, Eirik.
(2016)
One-step lipase-catalysed preparation of eslicarbazepine.
RSC Advances
Vitenskapelig artikkel
-
Bugge, Steffen;
Buene, Audun Formo;
Jurisch-Yaksi, Nathalie;
Moen, Ingri Ullestad;
Skjønsfjell, Ellen Martine;
Sundby, Eirik.
(2016)
Extended structure-activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Han, Jin;
Kaspersen, Svein Jacob;
Nervik, Sondre;
Nørsett, Kristin;
Sundby, Eirik;
Hoff, Bård Helge.
(2016)
Chiral 6-aryl-furo[2,3-d]pyrimidin-4-amines as EGFR
inhibitors.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Han, Jin;
Henriksen, Silje;
Nørsett, Kristin Gabestad;
Sundby, Eirik;
Hoff, Bård Helge.
(2016)
Balancing potency, metabolic stability and permeability in pyrrolopyrimidine-based EGFR inhibitors.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
2015
-
Bugge, Steffen;
Moen, Ingri Ullestad;
Sylte, Kent-Ove Kragseth;
Sundby, Eirik;
Hoff, Bård Helge.
(2015)
Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Sundby, Eirik;
Han, Jin;
Kaspersen, Svein Jacob;
Hoff, Bård Helge.
(2015)
In vitro baselining of new pyrrolopyrimidine EGFR-TK inhibitors with Erlotinib.
European Journal of Pharmaceutical Sciences
Vitenskapelig artikkel
2014
-
Bugge, Steffen;
Skjønsfjell, Ellen Martine;
Willumsen, Fredrik Bysting;
Sundby, Eirik;
Hoff, Bård Helge.
(2014)
Improved and Scalable Preparation of 6-Bromo-4-Chlorothieno[2,3-d]Pyrimidine.
Chemistry of Heterocyclic Compounds
Vitenskapelig artikkel
-
Kaspersen, Svein Jacob;
Han, Jin;
Nørsett, Kristin;
Rydså, Line;
Kjøbli, Eli;
Bugge, Steffen.
(2014)
Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4- amines as highly potent EGFR-TK inhibitors with Src-family activity.
European Journal of Pharmaceutical Sciences
Vitenskapelig artikkel
-
Bugge, Steffen;
Kaspersen, Svein Jacob;
Larsen, Synne;
Nonstad, Unni;
Bjørkøy, Geir;
Sundby, Eirik.
(2014)
Structure-activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
2013
-
Hoff, Bård Helge;
Sundby, Eirik.
(2013)
Preparation of pharmaceutical important fluorinated 1-arylethanols using isolated enzymes.
Bioorganic chemistry (Print)
Vitenskapelig oversiktsartikkel/review
-
Thvedt, Thor Håkon Krane;
Kaasa, Kristin;
Sundby, Eirik;
Charnock, Colin;
Hoff, Bård Helge.
(2013)
Chiral N-benzyl-N-methyl-1-(naphthalen-1-yl)ethanamines and their in vitro antifungal activity against Cryptococcus neoformans, Trichophyton mentagrophytes and Trichophyton rubrum.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Ali, Mohammed Farrag Mohammed;
Sundby, Eirik.
(2013)
Synthesis of the antiepileptic (R)-Stiripentol by a combination of lipase catalyzed resolution and alkene metathesis.
Tetrahedron: asymmetry
Vitenskapelig artikkel
-
Han, Jin;
Sundby, Eirik;
Hoff, Bård Helge.
(2013)
Solvent selection in synthesis of 4-(1-arylfluoroethoxy)quinazolines and thienopyrimidines.
Journal of fluorine chemistry
Vitenskapelig artikkel
2012
-
Bugge, Steffen;
Kaspersen, Svein Jacob;
Sundby, Eirik;
Hoff, Bård Helge.
(2012)
Route selection in the synthesis of C-4 and C-6 substituted thienopyrimidines.
Tetrahedron
Vitenskapelig artikkel
-
Esmurziev, Aslan;
Reimers, Arne;
Andreassen, Trygve;
Simic, Nebojsa;
Sundby, Eirik;
Hoff, Bård Helge.
(2012)
Benzoylated uronic Acid building blocks and synthesis of N-uronate conjugates of lamotrigine.
Molecules
Vitenskapelig artikkel
-
Jacobsen, Elisabeth Egholm;
Anthonsen, Thorleif;
El-Behairy, Mohammed Farrag ;
Sundby, Eirik;
Aboul-Enein, Mohamed Nabil;
Attia, Mohamed Ibrahim.
(2012)
Lipase Catalysed Kinetic Resolution of Stiripentol.
International Journal of Chemistry
Vitenskapelig artikkel
-
Kaspersen, Svein Jacob;
Sundby, Eirik;
Charnock, Colin;
Hoff, Bård Helge.
(2012)
Activity of 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines to Tetrahymena.
Bioorganic chemistry (Print)
Vitenskapelig artikkel
2011
-
Kaspersen, Svein Jacob;
Sørum, Christopher;
Willassen, Veronica;
Fuglseth, Erik;
Kjøbli, Eli;
Bjørkøy, Geir.
(2011)
Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Thvedt, Thor Håkon Krane;
Kristensen, Tor Erik Holt;
Sundby, Eirik;
Hansen, Tore;
Hoff, Bård Helge.
(2011)
Enantioselectivity, swelling and stability of 4-hydroxyprolinol containing acrylic polymer beads in the asymmetric reduction of ketones.
Tetrahedron: asymmetry
Vitenskapelig artikkel
-
Reimers, Arne;
Østby, Lene;
Stuen, Ina;
Sundby, Eirik.
(2011)
Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term.
European journal of drug metabolism and pharmacokinetics
Vitenskapelig artikkel
-
Slungård, Sigrid Volden;
Krakeli, Tor-Arne;
Thvedt, Thor Håkon Krane;
Fuglseth, Erik;
Sundby, Eirik;
Hoff, Bård Helge.
(2011)
Investigation into the enantioselection mechanism of ruthenium-arene-diamine transfer hydrogenation catalysts using fluorinated substrates.
Tetrahedron
Vitenskapelig artikkel
2010
-
Thvedt, Thor Håkon Krane;
Fuglseth, Erik;
Sundby, Eirik;
Hoff, Bård Helge.
(2010)
Enantioenriched 1-aryl-2-fluoroethylamines. Efficient lipase-catalysed resolution and limitations to the Mitsunobu inversion protocol.
Tetrahedron
Vitenskapelig artikkel
-
Sørum, Christopher;
Simic, Nebojsa;
Sundby, Eirik;
Hoff, Bård Helge.
(2010)
1H,13C and 19F NMR data of N-substituted 6-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amines in DMSO-d6.
Magnetic Resonance in Chemistry
Vitenskapelig artikkel
-
Esmurziev, Aslan;
Simic, Nebojsa;
Hoff, Bård Helge;
Sundby, Eirik.
(2010)
Synthesis and Structure Elucidation of Benzoylated Deoxyfluoropyranosides.
Journal of carbohydrate chemistry
Vitenskapelig artikkel
2009
-
Esmurziev, Aslan;
Sundby, Eirik;
Hoff, Bård Helge.
(2009)
Regioselective C-6 Hydrolysis of Methyl O-Benzoyl-pyranosides Catalysed by Candida Rugosa Lipase.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Esmurziev, Aslan;
Simic, N.;
Sundby, Eirik;
Hoff, Bård Helge.
(2009)
H-1 and C-13 NMR data of methyl tetra-O-benzoyl-D-pyranosides in acetone-d(6).
Magnetic Resonance in Chemistry
Vitenskapelig artikkel
-
Fuglseth, Erik;
Sundby, Eirik;
Hoff, Bård Helge.
(2009)
Ruthenium-catalysed asymmetric transfer hydrogenation of para-substituted alpha-fluoroacetophenones.
Journal of fluorine chemistry
Vitenskapelig artikkel
2008
-
Sundby, Eirik;
Frommholz, David.
(2008)
Conversion of Cod Liver Oil to Fatty Acid Methyl Esters Catalyzed by Various Lipases in a Solvent-free system.
HiST
Rapport
-
Fuglseth, Erik;
Sundby, Eirik;
Bruheim, Per;
Hoff, Bård Helge.
(2008)
Asymmetric reduction using (R)-MeCBS and determination of absolute configuration of para-substituted 2-fluoroarylethanols.
Tetrahedron: asymmetry
Vitenskapelig artikkel
2007
-
Sundby, Eirik.
(2007)
Lynkurs i organisk kjemi for ikke-kjemikere.
KMT/AFT
Kompendium
-
Jørgensen, Kåre B.;
Sundby, Eirik.
(2007)
The 21st International Symposium for Polycyclic Aromatic Compounds Om tjærestoffer i Trondheim.
Kjemi
Fagartikkel
-
Sundby, Eirik.
(2007)
Polyfunksjonell navnsetting.
KMT/AFT
Kompendium
2006
-
Østby, Lene;
Sundby, Eirik;
Krøkje, Åse.
(2006)
Evaluation of CYP1A protein induction, biotransformation capacity and DNA adduct formation in a rat hepatoma cell line (FAO), as biomarkers of organic contamination in environmental soil samples.
Water, Air and Soil Pollution
Vitenskapelig artikkel
-
Østby, Lene;
Sundby, Eirik;
Krøkje, Åse.
(2006)
Evaluation of CYP1A protein induction, biotransformation capacity and DNA adduct formation in a rat hepatoma cell line (Fao), as biomarkers of organic contamination in environmental soil samples.
Water, Air and Soil Pollution
Vitenskapelig artikkel
2004
-
Sundby, Eirik;
Holt, Jarle;
Vik, Anders;
Anthonsen, Thorleif.
(2004)
Chemoenzymatic synthesis of (2S)- and (2R)-2-(1,3-dithian-2-ylmethyl)oxirane.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Sundby, Eirik;
Perk, Lars;
Anthonsen, Thorleif;
Aasen, Arne Jørgen;
Hansen, Trond Vidar.
(2004)
Synthesis of (+)-goniothalamin and its enantiomer by combination of lipase catalyzed resolution and alkene metathesis.
Tetrahedron
Vitenskapelig artikkel
-
Sundby, Eirik;
Holt, Jarle;
Vik, Anders;
Anthonsen, Thorleif.
(2004)
Chemoenzymatic synthesis of (2S)- and (2R)-2-(1,3-dithian-2-ylmethyl)oxirane.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Sundby, Eirik;
Anthonsen, Thorleif;
Perk, L;
Aasen, Arne Jørgen;
Hansen, TV.
(2004)
Synthesis of (+)-Goniothalamin and its Enantiomer by Combination of Lipase Catalyzed Resolution and Alkene Metathesis.
Tetrahedron
Vitenskapelig artikkel
2003
-
Sundby, Eirik.
(2003)
Biological reductions and esterifications for the production of enantiopure secondary alcohols. Chemo-enzymatic synthesis of chiral building blocks with sulphurcontaining rings.
NTNU, Institutt for kjemi
Doktorgradsavhandling
-
Sundby, Eirik;
De Zotti, Martha;
Anthonsen, Thorleif.
(2003)
The Enantioselectivity of Reduction of Ethyl 4-bromo-3-oxobutanoate catalyzed by Geotrichum candidum depends on the Cofactor.
Journal of Molecular Catalysis B: Enzymatic
Vitenskapelig artikkel
2002
-
Sundby, Eirik;
Anthonsen, Thorleif;
Andersen, Morten Myhre;
Hoff, Bård Helge.
(2002)
Lipase catalysed resolution and microbial reduction for obtaining enantiopure 1-(2-thienyl)alkanols.
ARKIVOC
Vitenskapelig artikkel
1999
-
Anthonsen, Thorleif;
Hoff, Bård Helge;
Hofsløkken, Nini;
Skattebøl, Lars;
Sundby, Eirik.
(1999)
Synthesis of 1,3-dithianes and 1,3-dithiolanes. Baker´s yeast reduction and lipase-catalyzed resolution for synthesis of enantiopure derivatives.
Acta Chemica Scandinavica
Vitenskapelig artikkel
-
Anthonsen, Thorleif;
DÁrrigo, P;
Pedrocche-Fantoni, G;
Secundo, F;
Servi, Stefano;
Sundby, Eirik.
(1999)
Phospholipid hydrolysis in organic solvents catalysed by immobilised Phospholipase C.
Journal of Molecular Catalysis B: Enzymatic
Vitenskapelig artikkel
1998
-
Sundby, Eirik;
Azerad, Robert;
Anthonsen, Thorleif.
(1998)
2,2-Dimethyl-1,3-propanediol as protective group promotes microbial hydroxylation of cis bicyclo[3.3.0]octane-3,7-dione.
Biotechnology Letters
Vitenskapelig artikkel
Tidsskriftspublikasjoner
-
Aarhus, Thomas Ihle;
Teksum, Vilde;
Unger, Anke;
Habenberger, Peter;
Wolf, Alexander;
Eickhoff, Jan.
(2023)
Negishi Cross-Coupling in the Preparation of Benzyl Substituted Pyrrolo[2,3-d]pyrimidine Based CSF1R Inhibitors.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Aarhus, Thomas Ihle;
Bjørnstad, Frithjof Andreas;
Wolowczyk, Camilla Izabel;
Larsen, Kristin Uhlving;
Rognstad, Line;
Leithaug, Trygve.
(2023)
Synthesis and Development of Highly Selective Pyrrolo[2,3-d]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form.
Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Aarhus, Thomas Ihle;
Eickhoff, Jan;
Klebl, Bert;
Unger, Anke;
Boros, Johanna;
Choidas, Axel.
(2023)
A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Bjørnstad, Frithjof Andreas;
Sundby, Eirik;
Hoff, Bård Helge.
(2023)
Directed Lithiation of Protected 4-Chloropyrrolopyrimidine: Addition to Aldehydes and Ketones Aided by Bis(2-dimethylaminoethyl)ether.
Molecules
Vitenskapelig artikkel
-
Singleton, Amanda Holstad;
Bergum, Olaug Elisabeth Torheim;
Søgaard, Caroline Krogh;
Røst, Lisa M.;
Olsen, Cecilie Elisabeth;
Blindheim, Fredrik Heen.
(2023)
Activation of multiple stress responses in Staphylococcus aureus substantially lowers the minimal inhibitory concentration when combining two novel antibiotic drug candidates.
Frontiers in Microbiology
Vitenskapelig artikkel
-
Olsen, Cecilie Elisabeth;
Blindheim, Fredrik Heen;
Søgaard, Caroline Krogh;
Røst, Lisa M.;
Singleton, Amanda;
Bergum, Olaug Elisabeth Torheim.
(2022)
Halogenated Pyrrolopyrimidines with Low MIC on Staphylococcus aureus and Synergistic Effects with an Antimicrobial Peptide.
Antibiotics
Vitenskapelig artikkel
-
Blindheim, Fredrik Heen;
Thoresen Malme, Ane;
Dalhus, Bjørn;
Sundby, Eirik;
Hoff, Bård Helge.
(2021)
Synthesis and Evaluation of Fused Pyrimidines as E. coli Thymidylate Monophosphate Kinase Inhibitors.
ChemistrySelect
Vitenskapelig artikkel
-
El-Behairy, Mohammed Farrag;
Hassan, Rasha M.;
Sundby, Eirik.
(2021)
Enantioselective chromatographic separation and lipase catalyzed asymmetric resolution of biologically important chiral amines.
Separations
Vitenskapelig artikkel
-
Guttormsen, Yngve;
Moldes-Anaya, Angel;
Fjellaksel, Richard;
Oteiza, Ana;
Martin-Armas, Montserrat;
Lindemann, Marcel.
(2021)
Development of a carbon-11 labeled thienopyrimidine based radioligand for EGFR-tyrosine-kinase-inhibitor (TKI) specific PET imaging of glioblastoma.
Journal of Nuclear Medicine
Sammendrag/abstract
-
Guttormsen, Yngve;
Kranz, Mathias;
Fjellaksel, Richard;
Martin-Armas, Montserrat;
Oteiza, Ana;
Bihler, Julia.
(2021)
SP-015 - Preliminary evaluation of a novel carbon-11 labeled brain-penetrant EGFR-TKI radiotracer for brain cancer imaging.
Nuclear Medicine and Biology
Sammendrag/abstract
-
Blindheim, Fredrik Heen;
Olsen, Cecilie Elisabeth;
Søgaard, Caroline Krogh;
Otterlei, Marit;
Sundby, Eirik;
Hoff, Bård Helge.
(2021)
Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents
.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Sundby, Eirik;
Haugen, Ingrid Naterstad.
(2020)
Comparison of Students' Perceived Learning in Two Similar Lab Courses with Different Teaching Staffs.
Universal Journal of Educational Research
Vitenskapelig artikkel
-
Reiersølmoen, Ann Christin;
Aarhus, Thomas Ihle;
Eckelt, Sarah;
Nørsett, Kristin Gabestad;
Sundby, Eirik;
Hoff, Bård Helge.
(2019)
Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines.
Bioorganic chemistry (Print)
Vitenskapelig artikkel
-
Reiersølmoen, Ann Christin;
Han, Jin;
Sundby, Eirik;
Hoff, Bård Helge.
(2018)
Identification of fused pyrimidines as interleukin 17 secretion inhibitors.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Petrovic, Voin;
Olaisen, Camilla;
Sharma, Animesh;
Nepal, Anala;
Bugge, Steffen;
Sundby, Eirik.
(2017)
Changes in cellular signaling proteins in extracts from A549, H460, and U2OS cells treated with cisplatin or docetaxel.
Data in Brief
Vitenskapelig artikkel
-
Hoff, Bård Helge;
Sundby, Eirik.
(2017)
Is literature data useful for identifying enzyme catalysts for new substrates? A case study on reduction of 1-aryl-2-alkanoates.
Bioorganic chemistry (Print)
Vitenskapelig artikkel
-
Petrovic, Voin;
Olaisen, Camilla;
Sharma, Animesh;
Nepal, Anala;
Bugge, Steffen;
Sundby, Eirik.
(2017)
On-column trypsinization allows for re-use of matrix in modified multiplexed inhibitor beads assay.
Analytical Biochemistry
Vitenskapelig artikkel
-
Willumsen, Fredrik Bysting;
Bugge, Steffen;
Sundby, Eirik;
Hoff, Bård Helge.
(2017)
Investigation of Heck coupling on 6-bromo[2,3-d]thienopyrimidines for construction of new EGFR inhibitor lead structures.
RSC Advances
Vitenskapelig artikkel
-
El-Behairy, Mohammed Farrag;
Sundby, Eirik.
(2016)
One-step lipase-catalysed preparation of eslicarbazepine.
RSC Advances
Vitenskapelig artikkel
-
Bugge, Steffen;
Buene, Audun Formo;
Jurisch-Yaksi, Nathalie;
Moen, Ingri Ullestad;
Skjønsfjell, Ellen Martine;
Sundby, Eirik.
(2016)
Extended structure-activity study of thienopyrimidine-based EGFR inhibitors with evaluation of drug-like properties.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Han, Jin;
Kaspersen, Svein Jacob;
Nervik, Sondre;
Nørsett, Kristin;
Sundby, Eirik;
Hoff, Bård Helge.
(2016)
Chiral 6-aryl-furo[2,3-d]pyrimidin-4-amines as EGFR
inhibitors.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Han, Jin;
Henriksen, Silje;
Nørsett, Kristin Gabestad;
Sundby, Eirik;
Hoff, Bård Helge.
(2016)
Balancing potency, metabolic stability and permeability in pyrrolopyrimidine-based EGFR inhibitors.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Bugge, Steffen;
Moen, Ingri Ullestad;
Sylte, Kent-Ove Kragseth;
Sundby, Eirik;
Hoff, Bård Helge.
(2015)
Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Sundby, Eirik;
Han, Jin;
Kaspersen, Svein Jacob;
Hoff, Bård Helge.
(2015)
In vitro baselining of new pyrrolopyrimidine EGFR-TK inhibitors with Erlotinib.
European Journal of Pharmaceutical Sciences
Vitenskapelig artikkel
-
Bugge, Steffen;
Skjønsfjell, Ellen Martine;
Willumsen, Fredrik Bysting;
Sundby, Eirik;
Hoff, Bård Helge.
(2014)
Improved and Scalable Preparation of 6-Bromo-4-Chlorothieno[2,3-d]Pyrimidine.
Chemistry of Heterocyclic Compounds
Vitenskapelig artikkel
-
Kaspersen, Svein Jacob;
Han, Jin;
Nørsett, Kristin;
Rydså, Line;
Kjøbli, Eli;
Bugge, Steffen.
(2014)
Identification of new 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4- amines as highly potent EGFR-TK inhibitors with Src-family activity.
European Journal of Pharmaceutical Sciences
Vitenskapelig artikkel
-
Bugge, Steffen;
Kaspersen, Svein Jacob;
Larsen, Synne;
Nonstad, Unni;
Bjørkøy, Geir;
Sundby, Eirik.
(2014)
Structure-activity study leading to identification of a highly active thienopyrimidine based EGFR inhibitor.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Hoff, Bård Helge;
Sundby, Eirik.
(2013)
Preparation of pharmaceutical important fluorinated 1-arylethanols using isolated enzymes.
Bioorganic chemistry (Print)
Vitenskapelig oversiktsartikkel/review
-
Thvedt, Thor Håkon Krane;
Kaasa, Kristin;
Sundby, Eirik;
Charnock, Colin;
Hoff, Bård Helge.
(2013)
Chiral N-benzyl-N-methyl-1-(naphthalen-1-yl)ethanamines and their in vitro antifungal activity against Cryptococcus neoformans, Trichophyton mentagrophytes and Trichophyton rubrum.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Ali, Mohammed Farrag Mohammed;
Sundby, Eirik.
(2013)
Synthesis of the antiepileptic (R)-Stiripentol by a combination of lipase catalyzed resolution and alkene metathesis.
Tetrahedron: asymmetry
Vitenskapelig artikkel
-
Han, Jin;
Sundby, Eirik;
Hoff, Bård Helge.
(2013)
Solvent selection in synthesis of 4-(1-arylfluoroethoxy)quinazolines and thienopyrimidines.
Journal of fluorine chemistry
Vitenskapelig artikkel
-
Bugge, Steffen;
Kaspersen, Svein Jacob;
Sundby, Eirik;
Hoff, Bård Helge.
(2012)
Route selection in the synthesis of C-4 and C-6 substituted thienopyrimidines.
Tetrahedron
Vitenskapelig artikkel
-
Esmurziev, Aslan;
Reimers, Arne;
Andreassen, Trygve;
Simic, Nebojsa;
Sundby, Eirik;
Hoff, Bård Helge.
(2012)
Benzoylated uronic Acid building blocks and synthesis of N-uronate conjugates of lamotrigine.
Molecules
Vitenskapelig artikkel
-
Jacobsen, Elisabeth Egholm;
Anthonsen, Thorleif;
El-Behairy, Mohammed Farrag ;
Sundby, Eirik;
Aboul-Enein, Mohamed Nabil;
Attia, Mohamed Ibrahim.
(2012)
Lipase Catalysed Kinetic Resolution of Stiripentol.
International Journal of Chemistry
Vitenskapelig artikkel
-
Kaspersen, Svein Jacob;
Sundby, Eirik;
Charnock, Colin;
Hoff, Bård Helge.
(2012)
Activity of 6-aryl-pyrrolo[2,3-d]pyrimidine-4-amines to Tetrahymena.
Bioorganic chemistry (Print)
Vitenskapelig artikkel
-
Kaspersen, Svein Jacob;
Sørum, Christopher;
Willassen, Veronica;
Fuglseth, Erik;
Kjøbli, Eli;
Bjørkøy, Geir.
(2011)
Synthesis and in vitro EGFR (ErbB1) tyrosine kinase inhibitory activity of 4-N-substituted 6-aryl-7H-pyrrolo[2,3-d]pyrimidine-4-amines.
European Journal of Medicinal Chemistry
Vitenskapelig artikkel
-
Thvedt, Thor Håkon Krane;
Kristensen, Tor Erik Holt;
Sundby, Eirik;
Hansen, Tore;
Hoff, Bård Helge.
(2011)
Enantioselectivity, swelling and stability of 4-hydroxyprolinol containing acrylic polymer beads in the asymmetric reduction of ketones.
Tetrahedron: asymmetry
Vitenskapelig artikkel
-
Reimers, Arne;
Østby, Lene;
Stuen, Ina;
Sundby, Eirik.
(2011)
Expression of UDP-glucuronosyltransferase 1A4 in human placenta at term.
European journal of drug metabolism and pharmacokinetics
Vitenskapelig artikkel
-
Slungård, Sigrid Volden;
Krakeli, Tor-Arne;
Thvedt, Thor Håkon Krane;
Fuglseth, Erik;
Sundby, Eirik;
Hoff, Bård Helge.
(2011)
Investigation into the enantioselection mechanism of ruthenium-arene-diamine transfer hydrogenation catalysts using fluorinated substrates.
Tetrahedron
Vitenskapelig artikkel
-
Thvedt, Thor Håkon Krane;
Fuglseth, Erik;
Sundby, Eirik;
Hoff, Bård Helge.
(2010)
Enantioenriched 1-aryl-2-fluoroethylamines. Efficient lipase-catalysed resolution and limitations to the Mitsunobu inversion protocol.
Tetrahedron
Vitenskapelig artikkel
-
Sørum, Christopher;
Simic, Nebojsa;
Sundby, Eirik;
Hoff, Bård Helge.
(2010)
1H,13C and 19F NMR data of N-substituted 6-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amines in DMSO-d6.
Magnetic Resonance in Chemistry
Vitenskapelig artikkel
-
Esmurziev, Aslan;
Simic, Nebojsa;
Hoff, Bård Helge;
Sundby, Eirik.
(2010)
Synthesis and Structure Elucidation of Benzoylated Deoxyfluoropyranosides.
Journal of carbohydrate chemistry
Vitenskapelig artikkel
-
Esmurziev, Aslan;
Sundby, Eirik;
Hoff, Bård Helge.
(2009)
Regioselective C-6 Hydrolysis of Methyl O-Benzoyl-pyranosides Catalysed by Candida Rugosa Lipase.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Esmurziev, Aslan;
Simic, N.;
Sundby, Eirik;
Hoff, Bård Helge.
(2009)
H-1 and C-13 NMR data of methyl tetra-O-benzoyl-D-pyranosides in acetone-d(6).
Magnetic Resonance in Chemistry
Vitenskapelig artikkel
-
Fuglseth, Erik;
Sundby, Eirik;
Hoff, Bård Helge.
(2009)
Ruthenium-catalysed asymmetric transfer hydrogenation of para-substituted alpha-fluoroacetophenones.
Journal of fluorine chemistry
Vitenskapelig artikkel
-
Fuglseth, Erik;
Sundby, Eirik;
Bruheim, Per;
Hoff, Bård Helge.
(2008)
Asymmetric reduction using (R)-MeCBS and determination of absolute configuration of para-substituted 2-fluoroarylethanols.
Tetrahedron: asymmetry
Vitenskapelig artikkel
-
Jørgensen, Kåre B.;
Sundby, Eirik.
(2007)
The 21st International Symposium for Polycyclic Aromatic Compounds Om tjærestoffer i Trondheim.
Kjemi
Fagartikkel
-
Østby, Lene;
Sundby, Eirik;
Krøkje, Åse.
(2006)
Evaluation of CYP1A protein induction, biotransformation capacity and DNA adduct formation in a rat hepatoma cell line (FAO), as biomarkers of organic contamination in environmental soil samples.
Water, Air and Soil Pollution
Vitenskapelig artikkel
-
Østby, Lene;
Sundby, Eirik;
Krøkje, Åse.
(2006)
Evaluation of CYP1A protein induction, biotransformation capacity and DNA adduct formation in a rat hepatoma cell line (Fao), as biomarkers of organic contamination in environmental soil samples.
Water, Air and Soil Pollution
Vitenskapelig artikkel
-
Sundby, Eirik;
Holt, Jarle;
Vik, Anders;
Anthonsen, Thorleif.
(2004)
Chemoenzymatic synthesis of (2S)- and (2R)-2-(1,3-dithian-2-ylmethyl)oxirane.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Sundby, Eirik;
Perk, Lars;
Anthonsen, Thorleif;
Aasen, Arne Jørgen;
Hansen, Trond Vidar.
(2004)
Synthesis of (+)-goniothalamin and its enantiomer by combination of lipase catalyzed resolution and alkene metathesis.
Tetrahedron
Vitenskapelig artikkel
-
Sundby, Eirik;
Holt, Jarle;
Vik, Anders;
Anthonsen, Thorleif.
(2004)
Chemoenzymatic synthesis of (2S)- and (2R)-2-(1,3-dithian-2-ylmethyl)oxirane.
European Journal of Organic Chemistry
Vitenskapelig artikkel
-
Sundby, Eirik;
Anthonsen, Thorleif;
Perk, L;
Aasen, Arne Jørgen;
Hansen, TV.
(2004)
Synthesis of (+)-Goniothalamin and its Enantiomer by Combination of Lipase Catalyzed Resolution and Alkene Metathesis.
Tetrahedron
Vitenskapelig artikkel
-
Sundby, Eirik;
De Zotti, Martha;
Anthonsen, Thorleif.
(2003)
The Enantioselectivity of Reduction of Ethyl 4-bromo-3-oxobutanoate catalyzed by Geotrichum candidum depends on the Cofactor.
Journal of Molecular Catalysis B: Enzymatic
Vitenskapelig artikkel
-
Sundby, Eirik;
Anthonsen, Thorleif;
Andersen, Morten Myhre;
Hoff, Bård Helge.
(2002)
Lipase catalysed resolution and microbial reduction for obtaining enantiopure 1-(2-thienyl)alkanols.
ARKIVOC
Vitenskapelig artikkel
-
Anthonsen, Thorleif;
Hoff, Bård Helge;
Hofsløkken, Nini;
Skattebøl, Lars;
Sundby, Eirik.
(1999)
Synthesis of 1,3-dithianes and 1,3-dithiolanes. Baker´s yeast reduction and lipase-catalyzed resolution for synthesis of enantiopure derivatives.
Acta Chemica Scandinavica
Vitenskapelig artikkel
-
Anthonsen, Thorleif;
DÁrrigo, P;
Pedrocche-Fantoni, G;
Secundo, F;
Servi, Stefano;
Sundby, Eirik.
(1999)
Phospholipid hydrolysis in organic solvents catalysed by immobilised Phospholipase C.
Journal of Molecular Catalysis B: Enzymatic
Vitenskapelig artikkel
-
Sundby, Eirik;
Azerad, Robert;
Anthonsen, Thorleif.
(1998)
2,2-Dimethyl-1,3-propanediol as protective group promotes microbial hydroxylation of cis bicyclo[3.3.0]octane-3,7-dione.
Biotechnology Letters
Vitenskapelig artikkel
Rapport
-
Sundby, Eirik;
Frommholz, David.
(2008)
Conversion of Cod Liver Oil to Fatty Acid Methyl Esters Catalyzed by Various Lipases in a Solvent-free system.
HiST
Rapport
-
Sundby, Eirik.
(2007)
Lynkurs i organisk kjemi for ikke-kjemikere.
KMT/AFT
Kompendium
-
Sundby, Eirik.
(2007)
Polyfunksjonell navnsetting.
KMT/AFT
Kompendium
-
Sundby, Eirik.
(2003)
Biological reductions and esterifications for the production of enantiopure secondary alcohols. Chemo-enzymatic synthesis of chiral building blocks with sulphurcontaining rings.
NTNU, Institutt for kjemi
Doktorgradsavhandling
Undervisning
Emner
Formidling
2023
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Vitenskapelig foredragOlsen, Cecilie Elisabeth; Blindheim, Fredrik Heen; Sundby, Eirik; Hoff, Bård Helge. (2023) Halogenated pyrrolopyrimidines with antibacterial activity towards S. aureus. Universitetet i Oslo Organisk Kjemisk Vintermøte-OKV36 , Skeikampen 2023-01-05 - 2023-01-08
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Vitenskapelig foredragBjørnstad, Frithjof A; Sundby, Eirik; Hoff, Bård Helge. (2023) Directed lithiation of protected 4-chloropyrrolopyrimidine: addition to aldehydes and ketones aided by bis(2-dimethylaminoethyl)ether. Universitetet i Oslo Organisk Kjemisk Vintermøte-OKV36 , Skeikampen 2023-01-05 - 2023-01-08
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PosterSvergja, Hanne; Olsen, Cecilie Elisabeth; Sundby, Eirik; Hoff, Bård Helge. (2023) Acid catalyzed amination of 4-chloro-pyrrolo[2,3-d]pyrimidines with anilines. Universitetet i Oslo Organisk Kjemisk Vintermøte-OKV36 , Skeikampen 2023-01-05 - 2023-01-08
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PosterBathen, Mina; Olsen, Cecilie Elisabeth; Sundby, Eirik; Hoff, Bård Helge. (2023) Synthesis of aniline substituted heterocycles: searching for anticancer agents. Universitetet i Oslo Organisk Kjemisk Vintermøte-OKV36 , Skeikampen 2023-01-05 - 2023-01-08
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PosterElumalai, Vijayaragavan; Visnes, Torkild; Sundby, Eirik; Hoff, Bård Helge. (2023) Synthesis of pyrimidinyl guanidine derivatives for medicinal applications. Universitetet i Oslo Organisk Kjemisk Vintermøte-OKV36 , Skeikampen 2023-01-05 - 2023-01-08
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PosterØstby, Lene; Sundby, Eirik; Steinsbekk, Kristin Solum; Mehli, Lisbeth; Nonstad, Liv Anita; Ekeberg, IS. (2023) Fra kokebok til kontekstualisering i generell kjemi: Erfaringer fra implementering av casebasert laboratorieundervisning og medstudentvurdering . MNT-konferansen 2023-03-16 - 2023-03-17
2022
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Vitenskapelig foredragElumalai, Vijayaragavan; Olaisen, Camilla; Naderi, Sheida; To, Vu; Wågbø, Ane Marit; Klinkenberg, Geir. (2022) Small molecule inhibitors to modulate DNA repair-mediated gene regulation. UiO NORBER , Lillehammer 2022-09-23 - 2022-09-24
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Vitenskapelig foredragElumalai, Vijayaragavan; Olaisen, Camilla; Naderi, Sheida; To, Vu; Wågbø, Ane Marit; Klinkenberg, Geir. (2022) Small molecule inhibitors to modulate DNA repair-mediated gene regulation. UiO Oslo Epigenetics Symposium , Oslo 2022-09-07 - 2022-09-09
-
Vitenskapelig foredragJakobsen, Anita Nordeng; Steinsbekk, Kristin Solum; Østby, Lene; Sundby, Eirik; Kjøbli, Eli; Mehli, Lisbeth. (2022) Studentaktiv læring og vurdering i «store» grunnlagsemner; Hvordan få med oss alle?. Læringsfestivalen 2022-05-08 - 2022-05-09
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Vitenskapelig foredragWahl, Markus Solberg; Boucher, Susanne Aspen; Lamb, Jacob Joseph; Sundby, Eirik; Thomas, Peter James; Hjelme, Dag Roar. (2022) Towards in-situ state of health monitoring of lithium-ion batteries using internal fiber-optic sensors. The Electrochemical Society 241st ECS Meeting , Vancouver, Canada 2022-05-29 - 2022-06-02
2020
-
Vitenskapelig foredragBlindheim, Fredrik Heen; Hoff, Bård Helge; Sundby, Eirik. (2020) Towards bacterial thymidylate kinase inhibitors. Norwegian University of Life Sciences Organisk kjemisk Vintermøte 2020 , Skeikampen 2020-01-09 - 2020-01-12
-
PosterAarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge. (2020) Syntetic reactions in the pursuit of bioactive pyrrolo[2,3-d]pyrimidines. Norwegian University of Life Sciences Organisk kjemisk Vintermøte 2020 , Skeikampen 2020-01-09 - 2020-01-12
-
PosterOlsen, Cecilie Elisabeth; Blindheim, Fredrik Heen; Sundby, Eirik; Hoff, Bård Helge. (2020) Synthesis of an Imidazopyridinone-Based Thymidylate Kinase Inhibitor. Norwegian University of Life Sciences Organisk kjemisk Vintermøte 2020 , Skeikampen 2020-01-09 - 2020-01-12
2019
-
PosterBygdås, Håkon Steinholt; Aarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge. (2019) Evaluation of protective groups in synthesis towards substituted purines. University of Bergen Organisk Kjemisk Vintermøte OKV34 , Skeikampen 2019-01-10 - 2019-01-13
-
PosterAarhus, Thomas Ihle; Reiersølmoen, Ann Christin; Nørsett, Kristin Gabestad; Sundby, Eirik; Hoff, Bård Helge. (2019) Highly potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines. University of Bergen Organisk Kjemisk Vintermøte OKV34 , Skeikampen 2019-01-10 - 2019-01-13
-
PosterHaugen, Ingrid Naterstad; Sundby, Eirik. (2019) Sammenligning av gjennomføring, ressursbruk og læringskvalitet på like lab-kurs ved IMA. Læringsfestivalen 2019 2019-05-06 - 2019-05-07
-
PosterRognstad, Line; Tsui, Hay Man Hilde; Aarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge. (2019) Synthesis of 4,6-disubstituted pyrrolo[2,3,d]pyrimidines. University of Bergen Organisk Kjemisk Vintermøte OKV34 , Skeikampen 2019-01-10 - 2019-01-13
-
PosterSelmer-Olsen, Sigrid; Aarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge. (2019) Strategies towards substituted pyrrolopyridines. University of Bergen Organisk Kjemisk Vintermøte OKV34 , Skeikampen 2019-01-10 - 2019-01-13
-
PosterBlindheim, Fredrik Heen; Hoff, Bård Helge; Sundby, Eirik. (2019) Synthesis of novel thymidylate monophosphate kinase inhibitors. University of Bergen Organisk Kjemisk Vintermøte OKV34 , Skeikampen 2019-01-10 - 2019-01-13
2018
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PosterSkinderhaug, Jori; Hjøllo, Elisabeth; Aarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge. (2018) Synthetic strategies towards substituted purines. Norwegian University of Science and Technology (NTNU) Organisk Kjemisk Vintermøte OKV33 , Skeikampen 2018-01-11 - 2018-01-14
-
PosterRamsnes, Andreas B.; Aarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge. (2018) Synthesis of thienopyrimidine based EGFR inhibitors. Norwegian University of Science and Technology (NTNU) Organisk Kjemisk Vintermøte OKV33 , Skeikampen 2018-01-11 - 2018-01-14
-
Faglig foredragHoff, Bård Helge; Sundby, Eirik. (2018) Synthesis of fused pyrimidines and their EGFR inhibitory activity. Zelinsky Institute of Organic Chemistry Chemtrends-2018 , Moscow 2018-09-23 - 2018-09-29
2017
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PosterJohansen, Camilla; Aarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge. (2017) Synthetic strategies towards substituted pyrrolopyridines. University of Oslo Organisk Kjemisk Vintermøte OKV32 , Skeikampen 2017-01-12 - 2017-01-15
2016
-
PosterReiersølmoen, Ann Christin; Han, Jin; Sundby, Eirik; Hoff, Bård Helge. (2016) Synthesis of pyrrolopyrimidines with acrylate warehead for irreversible inhibition. Universitetet i Tromsø Organisk Kjemisk vintermøte OKV31 , Skeikampen 2016-01-07 - 2016-01-10
-
Vitenskapelig foredragHan, Jin; Sundby, Eirik; Hoff, Bård Helge. (2016) Balancing potency, metabolic stability and permeability in pyrrolopyrimidine based EGFR-TK inhibitors. Universitetet i Tromsø Organisk kjemisk vintermøte OKV31 , Skeikampen 2016-01-07 - 2016-01-10
-
PosterLarsen, Kristin Uhlving; Han, Jin; Aarhus, Thomas Ihle; Sundby, Eirik; Hoff, Bård Helge. (2016) Synthesis of pyrrolopyrimidines for use in SAR study of CSF-1R kinase. Universitetet i Tromsø Organisk Kjemisk vintermøte OKV31 , Skeikampen 2016-01-07 - 2016-01-10
2015
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PosterBuene, Audun Formo; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. (2015) Synthesis of amide containing thienopyrimidines. University of Stavanger Organisk kjemisk vintermøte OKV 30 , Skeikampen 2015-01-08 - 2015-01-11
-
PosterWillumsen, Fredrik Bysting; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. (2015) Optimization of Heck reaction on the thienopyrimidine scaffold. University of Stavanger Organisk kjemisk vintermøte OKV 30 , Skeikampen 2015-01-08 - 2015-01-11
-
Faglig foredragHan, Jin; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. (2015) Highly potent pyrrolo[2,3-d]pyrimidines as EGFR-TK inhibitors with interesting Src-familiy and CSF1R activity. University of Stavanger Organisk kjemisk Vintermøte OKV 30 , Skeikampen 2015-01-08 - 2015-01-11
-
PosterHenriksen, Silje; Han, Jin; Sundby, Eirik; Hoff, Bård Helge. (2015) Chiral pyrrolopyrimidine based EGFR inhibitors. University of Stavanger Organisk kjemisk vintermøte OKV 30 , Skeikampen 2015-01-08 - 2015-01-11
-
Vitenskapelig foredragHoff, Bård Helge; Sundby, Eirik. (2015) Thieno- and pyrrolopyrimidine based epidermal growth factor inhibitors: synthesis, SAR study, cellular profiling and ADME challenges. Dr. Arie Gruzman Lecture at Bar Ilan University , Bar Ilan University, Department of Chemistry 2015-11-19 - 2015-11-19
-
PosterHoff, Bård Helge; Sundby, Eirik; Han, Jin; Bugge, Steffen. (2015) Thieno- and Pyrrolo[2,3-d]pyrimidine base EGFR inhibitors and their ADME profile. European Federation for Medicinal Chemistry , International Symposium in Synthetic and Medicinal Chemistry , Rehovot 2015-11-15 - 2015-11-18
-
PosterNervik, Sondre; Han, Jin; Sundby, Eirik; Hoff, Bård Helge. (2015) Furopyrimidines as EGFR tyrosine kinase inhibitors. University of Stavanger Organisk kjemisk vintermøte OKV 30 , Skeikampen 2015-01-08 - 2015-01-11
-
PosterBekkevard, Pål Unnerud; Han, Jin; Sundby, Eirik; Hoff, Bård Helge. (2015) Instability of 7N-protected pyrrolo[2,3-d]pyrimidines. University of Stavanger Organisk kjemisk vintermøte , Skeikampen 2015-01-08 - 2015-01-11
2014
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Vitenskapelig foredragBugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. (2014) Structure-activity study leading to the identification of a highly active thienopyrimidine based EGFR inhibitor. Farmasutisk institutt, Universitetet i Oslo Organisk kjemisk vintermøte 2014 , Skeikampen 2014-01-09 - 2014-01-12
-
PosterHan, Jin; Bartling, Christian; Sundby, Eirik; Hoff, Bård Helge. (2014) Challanges in synthesis of electron rich furopyrimidines. Farmasøytisk institutt, Universitetet i Oslo Organisk kjemisk vintermøte 2014 , Skeikampen 2014-01-09 - 2014-01-12
-
PosterUllestad Moen, Ingri; Kragseth Sylte, Kent-Ove; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. (2014) Fragment based approach in the search for new kinase inhibitors. Farmasøytisk institutt, Universitetet i Oslo Organisk kjemisk vintermøte 2014 , Skeikampen 2014-01-09 - 2014-01-12
-
PosterHan, Jin; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. (2014) Highly potent pyrrolo[2,3-d]pyrimidines as EGFR-TK inhibitors with interesting Src-family and CSF1R activity. Royal Society of Chemistry Kinase 2014: Past, Present and Beyond. 19-20 May 2014 , Cambridge 2014-05-19 - 2014-05-20
-
PosterBugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. (2014) Use of the thienopyrimidine scaffold for development of new EGFR-TK inhibitors. Royal Society of Chemistry Kinase 2014: Past, Present and Beyond. 19-20 May 2014 , Cambridge 2014-05-19 - 2014-05-20
2013
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Vitenskapelig foredragKaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. (2013) Pyrrolopyrimidines as Potential EGFR Kinase Inhibitors. International Society of Heterocyclic Chemistry The 24. International Society of Heterocyclic Chemistry Congress , Shanghai 2013-09-08 - 2013-09-13
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Vitenskapelig foredragJacobsen, Elisabeth Egholm; El-Behairy, Mohammed Farrag; Sundby, Eirik; Anthonsen, Thorleif. (2013) Antiepileptic Drug (R)-Stiripentol by Lipase Catalysis. Eureka Conferences Inc. Nobel Laureate Ferid Murad Drug Discovery & Therapy World Congress 2013 , Boston, MA, 2013-06-03 - 2013-06-06
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PosterHan, Jin; Sundby, Eirik; Hoff, Bård Helge. (2013) Identifying mild coupling conditions for fluorinated alcohols. Universitetet i Bergen v/Bengt E. Haug Det 28. Organisk kjemiske vintermøte , Skeikampen 2013-01-10 - 2013-01-13
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PosterBugge, Steffen; Kaspersen, Svein Jacob; Lange, Sandra; Sundby, Eirik; Hoff, Bård Helge. (2013) Structure-activity study of thienopyrimidines as EGFR tyrosine kinase inhibitors. Universitetet i Bergen v/Bengt E. Haug Det 28. Organisk kjemiske vintermøte , Skeikampen 2013-01-10 - 2013-01-13
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PosterSkjønsfjell, Ellen Martine; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. (2013) Investigation and scale up of the synthesis of 6-bromo-4-chlorothieno[2,3-d]pyrimidine. Universitetet i Bergen v/ Bengt E. Haug Det 28. Organisk kjemiske vintermøte , Skeikampen 2013-01-10 - 2013-01-13
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PosterRydså, Line; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. (2013) Investigation of the synthesis of 6-iodo-4-chloroprrolo[2,3-d]pyrimidine. Universitetet i Bergen v/ Bengt E. Haug Det 28. Organisk kjemiske vintermøte , Skeikampen 2013-01-10 - 2013-01-13
2012
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PosterJacobsen, Elisabeth Egholm; Sundby, Eirik; El-Behairy, Mohammed Farrag; Anthonsen, Thorleif. (2012) Synthesis of chiral drugs by Candida antarctica lipase A catalysis. Center for Interdisciplinary Research (ZiF), Bielefeld Univ 7th CeBiTec Symposium: Bio-integrated Organic Synthesis in Industry: , Bielefeld Universitet, Bielefeld 2012-12-17 - 2012-12-19
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PosterHan, Jin; Larsen, Synne; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. (2012) Investigation into the synthesis of 2-aminopyrroles. Odd Reidar Gautun, NTNU Organisk kjemisk vintermøte 2012 , Skeikampen 2012-01-12 - 2012-01-15
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Vitenskapelig foredragKaspersen, Svein Jacob; Bjørkøy, Geir; Sundby, Eirik; Hoff, Bård Helge. (2012) In vitro testing of pyrrolopyrimidines as kinase inhibitors. Odd Reidar Gautun, NTNU Organisk kjemisk vintermøte 2012 , Skeikampen 2012-01-12 - 2012-01-15
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PosterZolubas, Giedrius; Bugge, Steffen; Thvedt, Thor Håkon Krane; Sundby, Eirik; Hoff, Bård Helge. (2012) Building blocks for thienopyrimidines synthezised using microwave heating. Odd Reidar Gautun, NTNU Organisk kjemisk vintermøte , Skeikampen 2012-01-12 - 2012-01-15
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Vitenskapelig foredragBugge, Steffen; Kaspersen, Svein Jacob; Sundby, Eirik; Hoff, Bård Helge. (2012) Route selection in synthesis of thienopyrimidines. Odd Reidar Gautun, NTNU Organisk kjemisk vintermøte 2012 , Skeikampen 2012-01-12 - 2012-01-15
2011
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PosterEl-Behairy, Mohammed Farrag; Jacobsen, Elisabeth Egholm; Sundby, Eirik; Skattebøl, Lars; Anthonsen, Thorleif. (2011) Kinetic resolution of dihalocyclopropyl alcohols. COST Action CM0701 CASCAT Sergio Riva COST Action CM0701 Biocatalysis Summer Training School , Siena 2011-04-27 - 2011-05-01
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PosterKaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. (2011) Pyrrolo-and thienopyrimidines as potential kinase inhibitors. NTNU, Strategic area medicinal technology The 2011 PhD Candidate seminar on medicinal technology , NTNU, Trondheim 2011-05-26 - 2011-05-26
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PosterThvedt, Thor Håkon Krane; Kaasa, Kristin; Sundby, Eirik; Charnock, Colin; Hoff, Bård Helge. (2011) Chiral derivatives of Butenafine and Terbinafine: synthesis and antifungal activity. University of Crete 17. European Symposium on Organic Chemistry , Hersonissos, Kreta 2011-07-10 - 2011-07-15
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PosterKaspersen, Svein Jacob; Bugge, Steffen; Sundby, Eirik; Hoff, Bård Helge. (2011) Pyrrolo- and thienopyrimidines as potential kinase inhibitors. University of Crete 17. European Symposium on Organic Chemistry , Hersonissos, Kreta 2011-07-10 - 2011-07-15
2010
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PosterJacobsen, Elisabeth Egholm; Sundby, Eirik; Anthonsen, Thorleif. (2010) Biocatalysis for Green chemistry. International Biographical Centre The World Forum, University of Cambridge , St. Johns College, University of Cambridge 2010-08-17 - 2010-08-22
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PosterKaspersen, Jacob; Willassen, Veronica; Sundby, Eirik; Hoff, Bård Helge. (2010) Pyrrolopyrimidines as potential kinase inhibitors. Organisk Kjemisk Vintermøte , Fefor 2010-01-07 - 2010-01-10
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PosterSlungård, Sigrid; Engøy, Ingemund; Fuglseth, Erik; Sundby, Eirik; Hoff, Bård Helge. (2010) Ruthenium catalysed asymmetric transfer hydrogenation of fluorinated ketones. Organisk Kjemisk Vintermøte , Fefor 2010-01-07 - 2010-01-10
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PosterThvedt, Thor Håkon Krane; Sundby, Eirik; Hoff, Bård Helge. (2010) Synthesis of new chiral building blocks: 1-aryl-2-fluoroethylamines. Organisk Kjemisk Vintermøte , Fefor 2010-01-07 - 2010-01-10
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Vitenskapelig foredragEsmurziev, Aslan; Hoff, Bård Helge; Sundby, Eirik. (2010) Chemo-enzymatic synthesis of benzoylated hexapyranosides and derivatives. Organisk Kjemisk Vintermøte , Fefor 2010-01-07 - 2010-01-10
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Vitenskapelig foredragHoff, Bård Helge; Thvedt, Thor Håkon Krane; Fuglseth, Erik; Sundby, Eirik. (2010) Microwave assisted side chain fluorination of 1-arylethanones. Organisk Kjemisk Vintermøte , Fefor 2010-01-07 - 2010-01-10
2009
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Vitenskapelig foredragSundby, Eirik. (2009) Enzymatic synthesis of benzoylated uronic acids using lipase hydrolysis and laccase oxidations in tandem. Cascade Chemoenzymatic Processes ¿ New Synergies Between Chemistry and Biochemistry , Como, Italia 2008-09-18 - 2009-09-21
2008
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PosterEsmurziev, Aslan; Hoff, Bård Helge; Sundby, Eirik. (2008) Regioselective enzymatic hydrolysis of tetrabenzoylated hexapyranosides. Biocatalysis in Non-Convential Media , Moskva, Russland 2008-06-11 - 2008-06-16
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PosterFuglseth, Erik; Thvedt, Thor Håkon Krane; Sundby, Eirik; Hoff, Bård Helge. (2008) Asymmetric reduction of 4¿-substituted _a-fluoroacetophenones. OKV 2008 , Geilo, Norway 2008-01-10 - 2008-01-13
2007
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PosterSundby, Eirik; Esmurziev, Aslan. (2007) Synthesis and characterisation of olanzapine N-10-glucuronide and lamotrigin N-2-glucuronide. Chemical synthesis of glucuronides , Trondheim 2007-10-16 - 2007-10-16
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PosterPettersen, Nina M.; Liu, Hui-Ling; Zahlsen, Kolbjørn; Sundby, Eirik; Johansen, Jon Eigill. (2007) Designer Internal Standards. OKV 2007 , Røros 2007-01-11 - 2007-01-14
2006
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PosterSundby, Eirik; Johansen, Jon Eigill. (2006) Chemoenzymatic synthesis of PAH-glucuronides. Organisk kjemisk vintermøte , Skeikampen 2006-01-12 - 2006-01-15
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PosterSundby, Eirik; Stuen, Ina. (2006) (2R,4R)-2,4-dimethyl-1,3-dithian as a chiral acyl anion equivalent. Organisk kjemisk vintermøte , Skeikampen 2006-01-12 - 2006-01-15
2005
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Vitenskapelig foredragSundby, Eirik; Liu, Hui-Ling; Fetzer, John; Johansen, Jon Eigill. (2005) Reference Standards for PAH Analysis and Reasearch. Dioxin 2005/ISPAC 20 , Toronto, Canada 2005-08-22 - 2005-08-26
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PosterSundby, Eirik. (2005) Metatese: En molekylær pardans med partnerbytte. Nobelprisen i kjemi 2005 Norsk Kjemisk Selskap Trondheim , Trondheim 2005-10-25 - 2005-10-25
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Intervju
2001
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Vitenskapelig foredragSundby, Eirik; De Zotti, Martha; Anthonsen, Thorleif. (2001) The enantioselectivity of reduction of ethyl 4-bromo-3-oxobutanoate catalysed by Geotrichum candium depends on the cofactor. Applied Biocatalysis 1980-2020: The future impact of modelling proteins and thermodynamics, 2001, NTNU, Trondheim, Norway , Norway, Trondheim, NTNU 2001-06-20 -
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PosterSundby, Eirik; Holt, Jarle; Anthonsen, Thorleif. (2001) Enantiopure 1-(1,3-dithian-2-yl)-3-halo-2-propanol. Building Blocks for Biologically Active Compounds by Lipase-Catalyzed Kinetic Resolution. Applied Biocatalysis 1980-2020: The future impact of modelling proteins and thermodynamics, 2001, NTNU, Trondheim, Norway , Norway, Trondheim, NTNU 2001-06-20 -
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PosterSundby, Eirik; De Zotti, Marta; Anthonsen, Thorleif. (2001) The Enantioselectivity of Reduction of Ethyl 4-bromo-3-oxobutanoate Catalyzed by Geotrichum candidum Depends on the Cofactor. 16th Norwegian Organic Chemistry Wintermeeting , Beito, 11.- 14. 1.
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PosterSundby, Eirik; Holt, Jarle; Anthonsen, Thorleif. (2001) Enantiopure 1-(1,3-dithian-2-yl)-4-halo-2-propanol as Building Blocks for Biologically Active Compounds by Lipase-Catalyzed Kinetic Resolution. 16th Norwegian Organic Chemistry Wintermeeting , Beito, 11.-14. 1.
2000
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Vitenskapelig foredragAnthonsen, Thorleif; Hoff, Bård Helge; Liu, Hui Ling; Sundby, Eirik. (2000) Enantiopure chiral building blocks by biocatalysis. Organisk kjemisk vintermøte , Geilo, januar 2000
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PosterSundby, Eirik; DeZotti, Marta; Anthonsen, Thorleif. (2000) The enantioselectivity of reduction of ethyl 4-bromo-3-oxobutanoate catalysed by Geotrichum candidum depends on the cofactor. Organic Transformations: Selective Processes and Asymmetric Catalysis, COST D12 Workshop , Fefro, Norway, 12.-15.10, 2000
1999
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Vitenskapelig foredragAnthonsen, Thorleif; Hoff, Bård Helge; Hoffsløkken, Nini; Skattebøl, Lars; Sundby, Eirik. (1999) Synthesis of Enantiopure 1,3-Dithianes and 1,3-Dithiolanes. 7. Nordic Conference on Biocatalysis in Organic Chemistry , Teveltunet fjellstue, 8.-11. april 1999
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PosterAnthonsen, Thorleif; Hoff, Bård Helge; Liu, Hui-Ling; Sundby, Eirik. (1999) Enantiopure chiral building blocks by biocatalysis. Metal and bio-promoted selective organic transformations. COST D12 Workshop , Sassari-Porto Conte, Italia, Oktober 1999