Pawel Sikorski
Bakgrunn og aktiviteter
My main scientific interest are in development of new hydrogel-based materials and composites, as well as in understanding of their properties. To do this we apply a range of material characterization techniques. Recently, we have established a new technique to form alginate gels, an approach which is compatible with 3D printing, microfluidic-based cell encapsulation, injectable preparations and large scale bubble and solid free mouldable gels. We have also developed a model system to study mineralisation of alginate and PEG hydrogels. In addition to work on biomaterials, my group has ongoing activities within bionanotechnology, in particular applications of nanofabrication to studies of cells. In the past I have worked extensively in the field of polymer physics and structural studies of crystalline polymers and biopolymers.
Education:
2001 Ph.D. in Polymer Physics, University of Bristol, UK 2002. Ph.D. thesis supervisor: Prof. E.D.T. Atkins
1998 M.Sc. in Material Science, with distinction, Wroclaw Univ. of Science and Technology, Poland
Employment:
2011 - present | Professor, Department of Physics, NTNU |
2005-2011 | Associate Professor, Department of Physics, NTNU |
2002-2005 | Post.Doc., Department of Physics/Department of Biotechnology, NTNU |
2001-2002 | Research Associate, Department of Physics, University of Bristol, UK |
Vitenskapelig, faglig og kunstnerisk arbeid
Et utvalg av nyere tidsskriftspublikasjoner, kunstneriske produksjoner, bok, inklusiv bokdeler og rapport-del. Se alle publikasjoner i databasen
Tidsskriftspublikasjoner
- (2019) Influence of Nanopillar Arrays on Fibroblast Motility, Adhesion, and Migration Mechanisms. Small. vol. 15 (43).
- (2019) Bio-instructive materials for musculoskeletal regeneration. Acta Biomaterialia.
- (2019) Towards a low CO2 emission building material employing bacterial metabolism (1/2): The bacterial system and prototype production. PLOS ONE. vol. 14 (4).
- (2019) Stabilisation of amorphous calcium phosphate in polyethylene glycol hydrogels. Acta Biomaterialia. vol. 90.
- (2019) Formation of Hydroxyapatite via Transformation of Amorphous Calcium Phosphate in the Presence of Alginate Additives. Crystal Growth & Design. vol. 19 (12).
- (2019) Local structure of Ca2+ alginate hydrogels gelled via competitive ligand exchange and measured by small angle X-ray scattering. Gels. vol. 5.
- (2017) Transformation of brushite to hydroxyapatite and effects of alginate additives. Journal of Crystal Growth. vol. 468.
- (2016) Competitive ligand exchange of crosslinking ions for ionotropic hydrogel formation. Journal of materials chemistry. B. vol. 4 (37).
- (2016) DCPD-alginate composites: a bioactive material for bone tissue engineering. Frontiers in Bioengineering and Biotechnology.
- (2016) Controlled mineralisation and recrystallisation of brushite within alginate hydrogels. Biomedical Materials. vol. 11 (1).
- (2016) A correlative spatiotemporal microscale study of calcium phosphate formation and transformation within an alginate hydrogel matrix. Acta Biomaterialia. vol. 44.
- (2016) Gelling kinetics and in situ mineralization of alginate hydrogels: A correlative spatiotemporal characterization toolbox. Acta Biomaterialia. vol. 44.
- (2016) Versatile, cell and chip friendly method to gel alginate in microfluidic devices. Lab on a Chip. vol. 16 (19).
- (2015) Dissolution of copper mineral phases in biological fluids and the controlled release of copper ions from mineralized alginate hydrogels. Biomedical Materials. vol. 10 (1).
- (2015) Design and development of a 3D printed PLA tissue engineering scaffold functionalized with alginate microbeads. European Cells and Materials. vol. 29.
- (2015) Tunable high aspect ratio polymer nanostructures for cell interfaces. Nanoscale. vol. 7 (18).
- (2015) Seeing a mycobacterium-infected cell in nanoscale 3D: Correlative imaging by light microscopy and FIB/SEM tomography. PLOS ONE. vol. 10:e0134644 (9).
- (2015) Raman and SEM characterization of early stage calcium phosphate mineral formation in an alginate matrix. European Cells and Materials. vol. 29.
- (2015) Nucleation and Growth of Brushite in the Presence of Alginate. Crystal Growth & Design. vol. 15 (11).
- (2015) Osteogenic differentiation of human mesenchymal stem cells in mineralized alginate matrices. PLOS ONE. vol. 10 (3).