Pål Sætrom
Om
Pål Sætrom bruker datamodeller for å studere hvordan endringer i genregulering kan kontrollere utvikling og forårsake sykdom. See the English version for details.
Publikasjoner
Kompetanseord
Publikasjoner
2024
-
Glærum, Ingvild Lynneberg;
Dunville, Keagan;
Moan, Kristian Magnus;
Krause, Maike;
Montaldo, Nicola Pietro;
Kirikae, Hinaco.
(2024)
Postnatal persistence of hippocampal Cajal-Retzius cells has a critical role in the establishment of the hippocampal circuit.
Development
Vitenskapelig artikkel
-
Bordin, Diana Lilian;
Grooms, Kayla Mae;
Montaldo, Nicola Pietro;
Fordyce Martin, Sarah L.;
Sætrom, Pål;
Samson, Leona D..
(2024)
Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory.
DNA Repair
Vitenskapelig artikkel
-
Neurauter, Christine Gran;
Pannone, Marco;
Sousa, Mirta;
Wang, Wei;
Kusnierczyk, Anna;
Luna, Luisa.
(2024)
Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Potenza, Maria Letizia;
Blankvoort, Stefan Matthias Adriaan;
Carvalho, Miguel;
Grimstvedt, Joachim Schweder;
Di Maria, Valentina;
Moan, Kristian Magnus.
(2024)
Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection.
Frontiers in Neuroscience
Vitenskapelig artikkel
-
Bugaj, Anna Maria;
Kunath, Nicolas;
Saasen, Vidar Langseth;
Fernandez-Berrocal, Marion S.;
Vankova, Ana;
Sætrom, Pål.
(2024)
Dissecting gene expression networks in the developing hippocampus through the lens of NEIL3 depletion.
Progress in Neurobiology
Vitenskapelig artikkel
2023
-
Urbarova, Ilona Halva;
Skogholt, Anne Heidi;
Sun, Yi-Qian;
Mai, Xiao-Mei;
Grønberg, Bjørn Henning;
Sandanger, Torkjel Manning.
(2023)
Increased expression of individual genes in whole blood is associated with late-stage lung cancer at and close to diagnosis.
Scientific Reports
Vitenskapelig artikkel
-
Lien, Hilde Julie Tokle;
Pedersen, Tina Therese;
Jakobsen, Bente;
Flatberg, Arnar;
Chawla, Konika;
Sætrom, Pål.
(2023)
Single-cell resolution of longitudinal blood transcriptome profiles in rheumatoid arthritis, systemic lupus erythematosus and healthy control pregnancies.
Annals of the Rheumatic Diseases
Vitenskapelig artikkel
-
Andersson-Rusch, Clara Leticia;
Quist-Løkken, Ingrid;
Sætrom, Pål;
Beisvag, Vidar;
Rolinski, Milosz;
Aas, Per Arne.
(2023)
Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma.
Blood
Sammendrag/abstract
-
Moholdt, Trine;
Ashby, Emily Rose;
Tømmerdal, Karina Hammer;
Lemoine, Maeliss Cynthia Chloe;
Holm, Rebecca Lyng;
Sætrom, Pål.
(2023)
Randomised controlled trial of exercise training during lactation on breast milk composition in breastfeeding people with overweight/obesity: a study protocol for the MILKSHAKE trial
.
BMJ Open sport & exercise medicine
Vitenskapelig artikkel
-
Pettersen, Caroline Hild Hakvåg;
Samdal, Helle;
Sætrom, Pål;
Wibe, Arne;
Hermansen, Erland;
Schønberg, Svanhild Margrethe Arentz.
(2023)
The Salmon Oil OmeGo Reduces Viability of Colorectal Cancer Cells and Potentiates the Anti-Cancer Effect of 5-FU.
Marine Drugs
Vitenskapelig artikkel
-
Olsen, Lene Christin;
Galler, Meital;
Witter, Menno Peter;
Sætrom, Pål;
O'Reilly, Kally C.
(2023)
Transcriptional development of the hippocampus and the dorsal–intermediate–ventral axis in rats.
Hippocampus
Vitenskapelig artikkel
-
Rocque, Mariève;
Leipart, Vilde;
Singh, Ashish Kumar;
Mur, Pilar;
Olsen, Maren Fridtjofsen;
Engebretsen, Lars Fredri.
(2023)
Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk.
Molecular Genetics and Genomics
Vitenskapelig artikkel
-
Baiju, Nikita;
Rylander, Karin Charlotta Maria;
Sætrom, Pål;
Sandanger, Torkjel M;
Nøst, Therese Haugdahl.
(2023)
Associations of gene expression in blood with BMI and weight changes among women in the Norwegian Women and Cancer postgenome cohort.
Obesity
Vitenskapelig artikkel
-
Lefol, Yohan Pierre;
Korfage, Tom;
Mjelle, Robin;
Prebensen, Christian Haugland;
Lüders, Torben;
Müller, Bruno.
(2023)
TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data.
NAR Genomics and Bioinformatics
Vitenskapelig artikkel
-
Konstantinidis, Ioannis;
Sætrom, Pål;
Fernandes, Jorge Manuel de Oliveira.
(2023)
Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance.
Scientific Data
Vitenskapelig artikkel
-
Konstantinidis, Ioannis;
Sætrom, Pål;
Brieuc, Marine Servane Ono;
Jakobsen, Kjetill Sigurd;
Liedtke, Hannes;
Pohlmann, Caroline.
(2023)
DNA hydroxymethylation differences underlie phenotypic divergence of somatic growth in Nile tilapia reared in common garden.
Epigenetics
Vitenskapelig artikkel
2022
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Røe, Oluf Dimitri;
Fotopoulos, I;
Nguyen, Olav Toai Duc;
Nøst, Therese Haugdahl;
Markaki, M;
Lagani, Vincenzo.
(2022)
Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study.
Journal of Thoracic Oncology
Sammendrag/abstract
-
Nøst, Therese Haugdahl;
Skogholt, Anne Heidi;
Urbarova, Ilona Halva;
Mjelle, Robin;
Paulsen, Erna-Elise;
Dønnem, Tom.
(2022)
Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer.
Molecular Oncology
Vitenskapelig artikkel
-
Grapotte, Mathys;
Saraswat, Manu;
Bessière, Chloé;
Menichelli, Christophe;
Ramilowski, Jordan A.;
Severin, Jessica.
(2022)
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7).
Nature Communications
Errata
2021
-
Solvin, Åshild Øksnevad;
Chawla, Konika;
Olsen, Lene Christin;
Hegre, Siv Anita;
Danielsen, Kjersti;
Jenssen, Marita.
(2021)
MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity.
Experimental Dermatology
Vitenskapelig artikkel
-
Konstantinidis, Ioannis;
Anastasiadi, Dafni;
Sætrom, Pål;
Nedoluzhko, Artem;
Mjelle, Robin;
Podgorniak, Tomasz.
(2021)
Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth.
Genomics
Vitenskapelig artikkel
-
Hildrestrand, Gunn Annette;
Rolseth, Veslemøy;
Kunath, Nicolas;
Suganthan, Rajikala;
Jensen, Vidar;
Bugaj, Anna Maria.
(2021)
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice.
Communications Biology
Vitenskapelig artikkel
-
Hegre, Siv Anita;
Samdal, Helle;
Klima, Antonin;
Stovner, Endre Bakken;
Nørsett, Kristin Gabestad;
Liabakk, Nina-Beate.
(2021)
Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation.
Scientific Reports
Vitenskapelig artikkel
-
Tingö, Lina;
Ahlberg, Emelie;
Johansson, Lovisa;
Pedersen, Sindre Andre;
Chawla, Konika;
Sætrom, Pål.
(2021)
Non-coding RNAs in human breast milk: A systematic review.
Frontiers in Immunology
Vitenskapelig oversiktsartikkel/review
-
Samdal, Helle;
Olsen, Lene Christin;
Grøn, Knut Sverre;
Røyset, Elin Synnøve;
Høiem, Therese Stork;
Nervik, Ingunn.
(2021)
Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids.
Biomedicines
Vitenskapelig artikkel
-
Baiju, Nikita;
Sandanger, Torkjel M;
Sætrom, Pål;
Nøst, Therese Haugdahl.
(2021)
Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort.
Scientific Reports
Vitenskapelig artikkel
-
Rolinski, Milosz;
Montaldo, Nicola Pietro;
Aksu, Merdane Ezgi;
Martin, Sarah Fordyce;
Brambilla, Alessandro;
Kunath, Nicolas.
(2021)
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
2020
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Konstantinidis, Ioannis;
Sætrom, Pål;
Mjelle, Robin;
Nedoluzhko, Artem;
Robledo, Diego;
Fernandes, Jorge Manuel de Oliveira.
(2020)
Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication.
Epigenetics
Vitenskapelig artikkel
-
Sarker, Debashis;
Plummer, Ruth;
Meyer, Tim;
Sodergren, Mikael H;
Basu, Bristi;
Chee, Cheng Ean.
(2020)
MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial.
Clinical Cancer Research
Vitenskapelig artikkel
-
Mjelle, Robin;
Aass, Kristin Roseth;
Sjursen, Wenche;
Hofsli, Eva;
Sætrom, Pål.
(2020)
sMETASeq: combined profiling of microbiota and host small RNAs.
iScience
Vitenskapelig artikkel
-
Huang, Kai-Wen;
Reebye, Vikash;
Czysz, Katherine;
Ciriello, Simona;
Dorman, Stephanie;
Reccia, Isabella.
(2020)
Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile.
Molecular Therapy Nucleic Acids
Vitenskapelig artikkel
2019
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Stovner, Endre Bakken;
Sætrom, Pål.
(2019)
PyRanges: efficient comparison of genomic intervals in Python.
Bioinformatics
Vitenskapelig artikkel
-
Solvin, Åshild Øksnevad;
Chawla, Konika;
Olsen, Lene Christin;
Danielsen, Kjersti;
Jenssen, Marita;
Furberg, Anne-Sofie.
(2019)
Differentially Expressed miRNAs and mRNAs in Psoriatic Skin.
Journal of Investigative Dermatology
Sammendrag/abstract
-
Solvin, Åshild Øksnevad;
Chawla, Konika;
Olsen, Lene Christin;
Danielsen, Kjersti;
Jenssen, Marita;
Furberg, Anne-Sofie.
(2019)
Combined mRNA and miRNA Analysis of Psoriatic Skin.
Forum for Nordic Dermato-Venereology
Sammendrag/abstract
-
Larose, Tricia L;
Sætrom, Pål;
Martinussen, Marit;
Skogseth, Haakon;
Sandanger, Torkjel M;
Scélo, Ghislaine.
(2019)
In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol.
Journal of Public Health Research
Vitenskapelig artikkel
-
Mjelle, Robin;
Sjursen, Wenche;
Thommesen, Liv;
Sætrom, Pål;
Hofsli, Eva.
(2019)
Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location.
BMC Cancer
Vitenskapelig artikkel
-
Zhao, Xiaoyang;
Reebye, Vikash;
Hitchen, Paul;
Fan, Jia;
Jiang, Hongchi;
Sætrom, Pål.
(2019)
Mechanisms involved in the activation of C/EBP? by small activating RNA in hepatocellular carcinoma.
Oncogene
Vitenskapelig artikkel
-
Kroustallaki, Pinelopi;
Lirussi, Lisa;
Carracedo Huroz, Sergio;
You, Panpan;
Esbensen, Qin Ying;
Götz, Alexandra.
(2019)
SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing.
Cell reports
Vitenskapelig artikkel
-
Mjelle, Robin;
Dima, Simona O;
Bacalbasa, Nicolae;
Chawla, Konika;
Sorop, Andrei;
Cucu, Dana.
(2019)
Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients.
BMC Cancer
Vitenskapelig artikkel
-
Montaldo, Nicola Pietro;
Bordin, Diana Lilian;
Brambilla, Alessandro;
Rösinger, Marcel;
Martin, Sarah Fordyce;
Bjørås, Karine Øian.
(2019)
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression.
Nature Communications
Vitenskapelig artikkel
-
Stovner, Endre Bakken;
Sætrom, Pål.
(2019)
epic2 efficiently finds diffuse domains in ChIP-seq data .
Bioinformatics
Vitenskapelig artikkel
-
Brian, Ben F;
Jolicoeur, Adrienne S;
Guerrero, Candace R.;
Nunez, Myra G;
Sychev, Zoi E;
Hegre, Siv Anita.
(2019)
Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells.
eLIFE
Vitenskapelig artikkel
2018
-
Sarno, Antonio;
Sætrom, Pål;
Kavli, Bodil Merete;
Pettersen, Henrik Sahlin.
(2018)
Genomic Uracil and Cancer.
World Scientific
Faglig kapittel
-
Reebye, Vikash;
Huang, Kai-Wen;
Lin, Vivian;
Jarvis, Sheba;
Cutilas, Pedro;
Dorman, Stephanie.
(2018)
Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer.
Oncogene
Vitenskapelig artikkel
2017
-
de rie, D;
Abugesaissa, I;
Alam, T;
Arner, E;
Ashoor, H;
Åström, G.
(2017)
An integrated expression atlas of miRNAs and their promoters in human and mouse.
Nature Biotechnology
Vitenskapelig artikkel
-
Voutila, Jon;
Reebye, Vikash;
Roberts, Thomas C.;
Protopapa, Pantelitsa;
Andrikakou, Pinelopi;
Blakey, David C..
(2017)
Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer.
Molecular Therapy
Vitenskapelig artikkel
-
Olsen, Maria Belland;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Vinge, Leif Erik;
Alfsnes, Katrine;
Palibrk, Vuk.
(2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.
Cell reports
Vitenskapelig artikkel
-
Olsen, Lene Christin;
O'Reilly, Kally;
Liabakk, Nina-Beate;
Witter, Menno;
Sætrom, Pål.
(2017)
MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex.
Brain Structure and Function
Vitenskapelig artikkel
-
Skogholt, Anne Heidi;
Ryeng, Einar;
Erlandsen, Sten Even;
Skorpen, Frank;
Arentz Schønberg, Svanhild Margrethe;
Sætrom, Pål.
(2017)
Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks.
BMC Research Notes
Vitenskapelig artikkel
-
Mjelle, Robin;
Sellæg, Kjersti;
Sætrom, Pål;
Thommesen, Liv;
Sjursen, Wenche;
Hofsli, Eva.
(2017)
Identification of metastasis-associated microRNAs in serum from rectal cancer patients.
OncoTarget
Vitenskapelig artikkel
-
Landfors, Miriam;
Johansen, Jostein;
Aronsen, Jan Magnus;
Vågbø, Cathrine Broberg;
Doré, Louis C.;
He, Chuan.
(2017)
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation.
Cell Discovery
Vitenskapelig artikkel
2016
-
Yoon, Sorah;
Huang, Kai-Wen;
Reebye, Vikash;
Mintz, Paul;
Tien, Yu-Wen;
Lai, Hong-Shiee.
(2016)
Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth in Vivo.
Molecular Therapy
Vitenskapelig artikkel
-
Stracquadanio, Giovanni;
Wang, Xuting;
Wallace, Marsha D;
Grawenda, Anna M.;
Zhang, Ping;
Hewitt, Juliet.
(2016)
The importance of p53 pathway genetics in inherited and somatic cancer genomes.
Nature Reviews Cancer
Vitenskapelig artikkel
-
Langkilde, Ane;
Olsen, Lene Christin;
Sætrom, Pål;
Drabløs, Finn Sverre;
Besenbacher, Søren;
Raaby, Line.
(2016)
Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α.
PLOS ONE
Vitenskapelig artikkel
-
Robles, Ana I.;
Olsen, Karina Standahl;
Tsui, Dana W.T.;
Georgoulias, Vassilis;
Creaney, Jenette;
Dobra, Katalin.
(2016)
Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.
Journal of Translational Medicine
Vitenskapelig artikkel
-
Røe, Oluf Dimitri;
Mjelle, Robin;
Sætrom, Pål;
Andreassen, Trygve;
Bathen, Tone Frost;
Hveem, Kristian.
(2016)
Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway.
Journal of Clinical Oncology
Sammendrag/abstract
2015
-
Achar, Avinash;
Sætrom, Pål.
(2015)
RNA motif discovery: a computational overview.
Biology Direct
Vitenskapelig oversiktsartikkel/review
-
Simpson, Melanie Rae;
Brede, Gaute;
Johansen, Jostein;
Johnsen, Roar;
Storrø, Ola;
Sætrom, Pål.
(2015)
Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring.
PLOS ONE
Vitenskapelig artikkel
-
Pettersen, Henrik Sahlin;
Galashevskaya, Anastasia;
Doseth, Berit;
Sousa, Mirta;
Sarno, Antonio;
Visnes, Torkild.
(2015)
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.
DNA Repair
Vitenskapelig artikkel
-
Hansen, Maren Fridtjofsen;
Johansen, Jostein;
Bjørnevoll, Inga;
Sylvander, Anna Elisabeth;
Steinsbekk, Kristin Solum;
Sætrom, Pål.
(2015)
A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine.
Familial Cancer
Vitenskapelig artikkel
-
Mjelle, Robin;
Hegre, Siv Anita;
Aas, Per Arne;
Slupphaug, Geir;
Drabløs, Finn;
Sætrom, Pål.
(2015)
Cell cycle regulation of human DNA repair and chromatin remodeling genes.
DNA Repair
Vitenskapelig artikkel
-
Hansen, Maren Fridtjofsen;
Johansen, Jostein;
Bjørnevoll, Inga;
Sylvander, Anna Elisabeth;
Steinsbekk, Kristin Solum;
Sætrom, Pål.
(2015)
A novel POLE variant, identified by exome sequencing, causes colorectal- and extra-colonic cancers.
Familial Cancer
Sammendrag/abstract
2014
-
Razick, Sabry;
Mocnik, Rok;
Thomas, Laurent;
Ryeng, Einar;
Drabløs, Finn;
Sætrom, Pål.
(2014)
The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences.
Database: The Journal of Biological Databases and Curation
Vitenskapelig artikkel
-
Reddy, MA;
Chen, Z;
Park, JT;
Wang, M;
Lanting, L;
Zhang, Q.
(2014)
Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA.
Diabetes
Vitenskapelig artikkel
-
Razick, Sabry;
Sætrom, Pål.
(2014)
The eGenVar Data Management System.
Programvare
-
Krokan, Hans Einar;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2014)
Error-free versus mutagenic processing of genomic uracil-Relevance to cancer.
DNA Repair
Vitenskapelig artikkel
-
Lange, LA;
Hu, Y;
Zhang, H;
Xue, C;
Schmidt, EM;
Tang, ZZ.
(2014)
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
American Journal of Human Genetics
Vitenskapelig artikkel
-
Mintz, PJ;
Huang, KW;
Reebye, V;
Nteliopoulos, G;
Lai, HS;
Sætrom, Pål.
(2014)
Exploiting Human CD34(+) Stem Cell-conditioned Medium for Tissue Repair.
Molecular Therapy
Vitenskapelig artikkel
-
Reebye, V;
Sætrom, Pål;
Mintz, PJ;
Huang, KW;
Swiderski, P;
Peng, L.
(2014)
A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo.
Hepatology
Vitenskapelig artikkel
-
Thomas, Laurent;
Sætrom, Pål.
(2014)
Circular RNAs are depleted of polymorphisms at microRNA binding sites.
Bioinformatics
Vitenskapelig artikkel
-
Johnsen, Ingvild Bjellmo;
Løvstakken, Lasse;
Åsvold, Bjørn Olav;
Høydal, Morten;
Sætrom, Pål;
Bonnevie, Tora.
(2014)
NTNUs stjerneforskere.
Adresseavisen
Intervju tidsskrift
2013
-
Leung, A;
Trac, C;
Jin, W;
Lanting, L;
Akbany, A;
Sætrom, Pål.
(2013)
Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells.
Circulation Research
Vitenskapelig artikkel
-
Sætrom, Pål.
(2013)
Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting.
Methods in molecular biology
Vitenskapelig artikkel
-
Hegre, Siv Anita;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Otterlei, Marit;
Krokan, Hans Einar.
(2013)
Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase.
DNA Repair
Vitenskapelig artikkel
-
Diaz, Javier Pena;
Hegre, Siv Anita;
Anderssen, Endre;
Aas, Per Arne;
Mjelle, Robin;
Gilfillan, Gregor Duncan.
(2013)
Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Chavali, Sreenivas;
Bruhn, Sören;
Tiemann, Katrin;
Sætrom, Pål;
Barrenäs, Fredrik;
Saito, Takaya.
(2013)
MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases.
RNA: A publication of the RNA Society
Vitenskapelig artikkel
-
Lundbæk, Marie B;
Sætrom, Pål.
(2013)
RNAi Screening and Assays.
John Wiley & Sons
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
-
Reebye, Vikash;
Sætrom, Pål;
Mintz, Paul J;
Rossi, JJ;
Kasahara, Noriyuki;
Nteliopoulos, G.
(2013)
A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells.
Molecular Therapy Nucleic Acids
Vitenskapelig artikkel
2012
-
Sjögren, A.-K.M.;
Barrenäs, Fredrik;
Muraro, Antonella;
Gustafsson, M;
Sætrom, Pål;
Wang, H.
(2012)
Monozygotic twins discordant for intermittent allergic rhinitis differ in mRNA and protein levels.
Allergy. European Journal of Allergy and Clinical Immunology
Vitenskapelig artikkel
-
Thomas, Laurent;
Sætrom, Pål.
(2012)
Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation.
PLoS Computational Biology
Vitenskapelig artikkel
-
Mintz, Paul J;
Sætrom, Pål;
Reebye, Vikash;
Lundbæk, Marie Benner;
Lao, Kaiqin;
Rossi, John J.
(2012)
MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood.
Molecular Therapy Nucleic Acids
Vitenskapelig artikkel
-
Voutila, J;
Sætrom, Pål;
Mintz, Paul J;
Sun, Guihua;
Alluin, Jessica;
Rossi, JJ.
(2012)
Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells.
Molecular Therapy Nucleic Acids
Vitenskapelig artikkel
-
Saito, Takaya;
Sætrom, Pål.
(2012)
Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments.
Silence
Vitenskapelig artikkel
-
Håndstad, Tony;
Rye, Morten Beck;
Mocnik, Rok;
Drabløs, Finn;
Sætrom, Pål.
(2012)
Cell-type specificity of ChIP-predicted transcription factor binding sites.
BMC Genomics
Vitenskapelig artikkel
2011
-
Rye, Morten Beck;
Sætrom, Pål;
Drabløs, Finn.
(2011)
A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Rye, Morten Beck;
Sætrom, Pål;
Håndstad, Tony;
Drabløs, Finn.
(2011)
Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements.
BMC Biology
Vitenskapelig artikkel
-
Lundbæk, Marie Benner;
Sætrom, Pål.
(2011)
Unconventional RNA interference – recent approaches to robust RNAi.
European Pharmaceutical Review
Fagartikkel
-
Håndstad, Tony;
Rye, Morten Beck;
Drabløs, Finn;
Sætrom, Pål.
(2011)
A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites.
PLOS ONE
Vitenskapelig artikkel
-
Thomas, Laurent;
Saito, Takaya;
Sætrom, Pål.
(2011)
Inferring causative variants in microRNA target sites.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
2010
-
Saito, Takaya;
Sætrom, Pål.
(2010)
A two-step site and mRNA-level model for predicting microRNA targets.
BMC Bioinformatics
Vitenskapelig artikkel
-
Saito, Takaya;
Sætrom, Pål.
(2010)
MicroRNAs – targeting and target prediction.
New Biotechnology
Vitenskapelig oversiktsartikkel/review
-
Ehsani, A;
Sætrom, Pål;
Zhang, J;
Alluin, J;
Li, HT;
Snøve, Ola.
(2010)
Rational Design of Micro-RNA-like Bifunctional siRNAs Targeting HIV and the HIV Coreceptor CCR5.
Molecular Therapy
Vitenskapelig artikkel
-
Tiemann, Katrin;
Höhn, Britta;
Ehsani, Ali;
Forman, Stephen J.;
Rossi, John J.;
Sætrom, Pål.
(2010)
Dual-targeting siRNAs.
RNA: A publication of the RNA Society
Vitenskapelig artikkel
-
Matveeva, OV;
Kang, YB;
Spiridonov, AN;
Sætrom, Pål;
Nemtsov, VA;
Ogurtsov, AY.
(2010)
Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design.
PLOS ONE
Vitenskapelig artikkel
2009
-
Sætrom, Pål;
Klein, Joern.
(2009)
miRNA and viral infections in vertebrates.
European Pharmaceutical Review
Vitenskapelig oversiktsartikkel/review
-
Sætrom, Pål;
Biesinger, Jacob;
Li, Sierra M.;
Smith, David;
Thomas, Laurent Francois;
Majzoub, Karim.
(2009)
A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis.
Cancer Research
Vitenskapelig artikkel
-
Snøve, Ola;
Sætrom, Pål.
(2009)
Animal MicroRNA gene prediction.
CRC Press
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
2008
-
Kim, Daniel H.;
S�trom, P�l;
Sn�ve, Ola;
Rossi, John J..
(2008)
MicroRNA-directed transcriptional gene silencing in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Vitenskapelig artikkel
-
Soifer, Harris S.;
Sano, Masayuki;
Sakurai, Kumi;
Chomchan, Pritsana;
S�trom, P�l;
Sherman, Mark A..
(2008)
A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Aagaard, Lars;
Zhang, J;
von Eije, K J;
Li, H;
Saetrom, P;
S�trom, P�l.
(2008)
Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs.
Gene Therapy
Vitenskapelig artikkel
-
Lee, N.S.;
Kim, J.S.;
Cho, W.J.;
Lee, M.R.;
Steiner, R.;
Gompers, A..
(2008)
miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression.
Biochemical and Biophysical Research Communications - BBRC
Vitenskapelig artikkel
-
Smith, DD;
Sætrom, Pål;
Snøve, Ola;
Lundberg, C;
Rivas, GE;
Glackin, C.
(2008)
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation.
BMC Bioinformatics
Vitenskapelig artikkel
2007
-
Sætrom, Pål;
Snøve, Ola;
Rossi, John J..
(2007)
Epigenetics and MicroRNAs.
Pediatric Research
Vitenskapelig oversiktsartikkel/review
-
Soifer, Harris S.;
Rossi, John J.;
Sætrom, Pål.
(2007)
MicroRNAs in Disease and Potential Therapeutic Applications.
Molecular Therapy
Vitenskapelig oversiktsartikkel/review
-
Von Eije, KJ;
Aagaard, Lars;
Sætrom, Pål;
Amarzguioui, M;
Li, HT;
Rossi, JJ.
(2007)
Prevention of HIV-1 viral escape upon RNAi treatment: Expression systems that generate multiple anti-HIV siRNAs.
Human Gene Therapy
Sammendrag/abstract
-
Helvik, Snorre Andreas;
Snøve, Ola;
Sætrom, Pål.
(2007)
Reliable prediction of Drosha processing sites improves microRNA gene prediction.
Bioinformatics
Vitenskapelig artikkel
-
Sætrom, Pål;
Snøve, Ola.
(2007)
Robust machine learning algorithms predict microRNA genes and targets.
Methods in Enzymology
Vitenskapelig artikkel
-
Håndstad, Tony;
Hestnes, Arne Johan Husebø;
Sætrom, Pål.
(2007)
Motif kernel generated by genetic programming improves remote homology and fold detection.
BMC Bioinformatics
Vitenskapelig artikkel
-
Matveeva, Olga;
Nechipurenko, Yury;
Rossi, Leo;
Moore, Barry;
Sætrom, Pål;
Ogurtsov, Aleksey Y..
(2007)
Comparison of approaches for rational siRNA design leading to a new efficient and transparent method.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Sætrom, Pål;
Heale, Bret S.;
Snøve, Ola;
Aagaard, Lars;
Alluin, Jessica;
Rossi, John J..
(2007)
Distance constraints between microRNA target sites dictate efficacy and cooperativity.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Sætrom, Pål.
(2007)
Hardware accelerated genetic programming for pattern mining in strings.
Doktoravhandlinger ved NTNU (197)
Doktorgradsavhandling
-
Sætrom, Pål;
Snøve, Ola.
(2007)
Machine learning predicts microRNA target sites.
Cambridge University Press
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
-
Sætrom, Pål;
Birkeland, Olaf René;
Snøve, Ola.
(2007)
Boosting Improves Stability and Accuracy of Genetic Programming in Biological Sequence Classification.
Springer
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
2006
-
Snøve, Ola;
Sætrom, Pål.
(2006)
Nobelpris for RNA-interferens.
Tidsskrift for Den norske legeforening
Leder
-
Helvik, Snorre Andreas;
Snøve, Ola;
Sætrom, Pål.
(2006)
Reliable prediction of Drosha processing sites improves microRNA gene prediction.
Bioinformatics
Vitenskapelig artikkel
-
Birkeland, Olaf René;
Snøve, Ola;
Halaas, Arne;
Nedland, Magnar;
Sætrom, Pål.
(2006)
The petacomp Machine - A MIMD Cluster for parallel pattern-mining.
Proceedings IEEE International Conference on Cluster Computing
Vitenskapelig artikkel
2005
-
Sætrom, Pål.
(2005)
Hardware accelerated genetic programming for pattern mining in strings.
Doktoravhandlinger ved NTNU (2005:197)
Doktorgradsavhandling
Tidsskriftspublikasjoner
-
Glærum, Ingvild Lynneberg;
Dunville, Keagan;
Moan, Kristian Magnus;
Krause, Maike;
Montaldo, Nicola Pietro;
Kirikae, Hinaco.
(2024)
Postnatal persistence of hippocampal Cajal-Retzius cells has a critical role in the establishment of the hippocampal circuit.
Development
Vitenskapelig artikkel
-
Bordin, Diana Lilian;
Grooms, Kayla Mae;
Montaldo, Nicola Pietro;
Fordyce Martin, Sarah L.;
Sætrom, Pål;
Samson, Leona D..
(2024)
Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory.
DNA Repair
Vitenskapelig artikkel
-
Neurauter, Christine Gran;
Pannone, Marco;
Sousa, Mirta;
Wang, Wei;
Kusnierczyk, Anna;
Luna, Luisa.
(2024)
Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Potenza, Maria Letizia;
Blankvoort, Stefan Matthias Adriaan;
Carvalho, Miguel;
Grimstvedt, Joachim Schweder;
Di Maria, Valentina;
Moan, Kristian Magnus.
(2024)
Generation of an enhancer-driven gene expression viral tool specific to dentate granule cell-types through direct hippocampal injection.
Frontiers in Neuroscience
Vitenskapelig artikkel
-
Bugaj, Anna Maria;
Kunath, Nicolas;
Saasen, Vidar Langseth;
Fernandez-Berrocal, Marion S.;
Vankova, Ana;
Sætrom, Pål.
(2024)
Dissecting gene expression networks in the developing hippocampus through the lens of NEIL3 depletion.
Progress in Neurobiology
Vitenskapelig artikkel
-
Urbarova, Ilona Halva;
Skogholt, Anne Heidi;
Sun, Yi-Qian;
Mai, Xiao-Mei;
Grønberg, Bjørn Henning;
Sandanger, Torkjel Manning.
(2023)
Increased expression of individual genes in whole blood is associated with late-stage lung cancer at and close to diagnosis.
Scientific Reports
Vitenskapelig artikkel
-
Lien, Hilde Julie Tokle;
Pedersen, Tina Therese;
Jakobsen, Bente;
Flatberg, Arnar;
Chawla, Konika;
Sætrom, Pål.
(2023)
Single-cell resolution of longitudinal blood transcriptome profiles in rheumatoid arthritis, systemic lupus erythematosus and healthy control pregnancies.
Annals of the Rheumatic Diseases
Vitenskapelig artikkel
-
Andersson-Rusch, Clara Leticia;
Quist-Løkken, Ingrid;
Sætrom, Pål;
Beisvag, Vidar;
Rolinski, Milosz;
Aas, Per Arne.
(2023)
Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma.
Blood
Sammendrag/abstract
-
Moholdt, Trine;
Ashby, Emily Rose;
Tømmerdal, Karina Hammer;
Lemoine, Maeliss Cynthia Chloe;
Holm, Rebecca Lyng;
Sætrom, Pål.
(2023)
Randomised controlled trial of exercise training during lactation on breast milk composition in breastfeeding people with overweight/obesity: a study protocol for the MILKSHAKE trial
.
BMJ Open sport & exercise medicine
Vitenskapelig artikkel
-
Pettersen, Caroline Hild Hakvåg;
Samdal, Helle;
Sætrom, Pål;
Wibe, Arne;
Hermansen, Erland;
Schønberg, Svanhild Margrethe Arentz.
(2023)
The Salmon Oil OmeGo Reduces Viability of Colorectal Cancer Cells and Potentiates the Anti-Cancer Effect of 5-FU.
Marine Drugs
Vitenskapelig artikkel
-
Olsen, Lene Christin;
Galler, Meital;
Witter, Menno Peter;
Sætrom, Pål;
O'Reilly, Kally C.
(2023)
Transcriptional development of the hippocampus and the dorsal–intermediate–ventral axis in rats.
Hippocampus
Vitenskapelig artikkel
-
Rocque, Mariève;
Leipart, Vilde;
Singh, Ashish Kumar;
Mur, Pilar;
Olsen, Maren Fridtjofsen;
Engebretsen, Lars Fredri.
(2023)
Characterization of POLE c.1373A > T p.(Tyr458Phe), causing high cancer risk.
Molecular Genetics and Genomics
Vitenskapelig artikkel
-
Baiju, Nikita;
Rylander, Karin Charlotta Maria;
Sætrom, Pål;
Sandanger, Torkjel M;
Nøst, Therese Haugdahl.
(2023)
Associations of gene expression in blood with BMI and weight changes among women in the Norwegian Women and Cancer postgenome cohort.
Obesity
Vitenskapelig artikkel
-
Lefol, Yohan Pierre;
Korfage, Tom;
Mjelle, Robin;
Prebensen, Christian Haugland;
Lüders, Torben;
Müller, Bruno.
(2023)
TiSA: TimeSeriesAnalysis - A pipeline for the analysis of longitudinal transcriptomics data.
NAR Genomics and Bioinformatics
Vitenskapelig artikkel
-
Konstantinidis, Ioannis;
Sætrom, Pål;
Fernandes, Jorge Manuel de Oliveira.
(2023)
Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance.
Scientific Data
Vitenskapelig artikkel
-
Konstantinidis, Ioannis;
Sætrom, Pål;
Brieuc, Marine Servane Ono;
Jakobsen, Kjetill Sigurd;
Liedtke, Hannes;
Pohlmann, Caroline.
(2023)
DNA hydroxymethylation differences underlie phenotypic divergence of somatic growth in Nile tilapia reared in common garden.
Epigenetics
Vitenskapelig artikkel
-
Røe, Oluf Dimitri;
Fotopoulos, I;
Nguyen, Olav Toai Duc;
Nøst, Therese Haugdahl;
Markaki, M;
Lagani, Vincenzo.
(2022)
Common MicroRNAs in Pre-diagnostic Serum Associated with Lung Cancer in Two Cohorts up to Eight Years Before Diagnosis: A HUNT Study.
Journal of Thoracic Oncology
Sammendrag/abstract
-
Nøst, Therese Haugdahl;
Skogholt, Anne Heidi;
Urbarova, Ilona Halva;
Mjelle, Robin;
Paulsen, Erna-Elise;
Dønnem, Tom.
(2022)
Increased levels of microRNA-320 in blood serum and plasma is associated with imminent and advanced lung cancer.
Molecular Oncology
Vitenskapelig artikkel
-
Grapotte, Mathys;
Saraswat, Manu;
Bessière, Chloé;
Menichelli, Christophe;
Ramilowski, Jordan A.;
Severin, Jessica.
(2022)
Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (Nature Communications, (2021), 12, 1, (3297), 10.1038/s41467-021-23143-7).
Nature Communications
Errata
-
Solvin, Åshild Øksnevad;
Chawla, Konika;
Olsen, Lene Christin;
Hegre, Siv Anita;
Danielsen, Kjersti;
Jenssen, Marita.
(2021)
MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity.
Experimental Dermatology
Vitenskapelig artikkel
-
Konstantinidis, Ioannis;
Anastasiadi, Dafni;
Sætrom, Pål;
Nedoluzhko, Artem;
Mjelle, Robin;
Podgorniak, Tomasz.
(2021)
Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth.
Genomics
Vitenskapelig artikkel
-
Hildrestrand, Gunn Annette;
Rolseth, Veslemøy;
Kunath, Nicolas;
Suganthan, Rajikala;
Jensen, Vidar;
Bugaj, Anna Maria.
(2021)
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice.
Communications Biology
Vitenskapelig artikkel
-
Hegre, Siv Anita;
Samdal, Helle;
Klima, Antonin;
Stovner, Endre Bakken;
Nørsett, Kristin Gabestad;
Liabakk, Nina-Beate.
(2021)
Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation.
Scientific Reports
Vitenskapelig artikkel
-
Tingö, Lina;
Ahlberg, Emelie;
Johansson, Lovisa;
Pedersen, Sindre Andre;
Chawla, Konika;
Sætrom, Pål.
(2021)
Non-coding RNAs in human breast milk: A systematic review.
Frontiers in Immunology
Vitenskapelig oversiktsartikkel/review
-
Samdal, Helle;
Olsen, Lene Christin;
Grøn, Knut Sverre;
Røyset, Elin Synnøve;
Høiem, Therese Stork;
Nervik, Ingunn.
(2021)
Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids.
Biomedicines
Vitenskapelig artikkel
-
Baiju, Nikita;
Sandanger, Torkjel M;
Sætrom, Pål;
Nøst, Therese Haugdahl.
(2021)
Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort.
Scientific Reports
Vitenskapelig artikkel
-
Rolinski, Milosz;
Montaldo, Nicola Pietro;
Aksu, Merdane Ezgi;
Martin, Sarah Fordyce;
Brambilla, Alessandro;
Kunath, Nicolas.
(2021)
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Konstantinidis, Ioannis;
Sætrom, Pål;
Mjelle, Robin;
Nedoluzhko, Artem;
Robledo, Diego;
Fernandes, Jorge Manuel de Oliveira.
(2020)
Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication.
Epigenetics
Vitenskapelig artikkel
-
Sarker, Debashis;
Plummer, Ruth;
Meyer, Tim;
Sodergren, Mikael H;
Basu, Bristi;
Chee, Cheng Ean.
(2020)
MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial.
Clinical Cancer Research
Vitenskapelig artikkel
-
Mjelle, Robin;
Aass, Kristin Roseth;
Sjursen, Wenche;
Hofsli, Eva;
Sætrom, Pål.
(2020)
sMETASeq: combined profiling of microbiota and host small RNAs.
iScience
Vitenskapelig artikkel
-
Huang, Kai-Wen;
Reebye, Vikash;
Czysz, Katherine;
Ciriello, Simona;
Dorman, Stephanie;
Reccia, Isabella.
(2020)
Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile.
Molecular Therapy Nucleic Acids
Vitenskapelig artikkel
-
Stovner, Endre Bakken;
Sætrom, Pål.
(2019)
PyRanges: efficient comparison of genomic intervals in Python.
Bioinformatics
Vitenskapelig artikkel
-
Solvin, Åshild Øksnevad;
Chawla, Konika;
Olsen, Lene Christin;
Danielsen, Kjersti;
Jenssen, Marita;
Furberg, Anne-Sofie.
(2019)
Differentially Expressed miRNAs and mRNAs in Psoriatic Skin.
Journal of Investigative Dermatology
Sammendrag/abstract
-
Solvin, Åshild Øksnevad;
Chawla, Konika;
Olsen, Lene Christin;
Danielsen, Kjersti;
Jenssen, Marita;
Furberg, Anne-Sofie.
(2019)
Combined mRNA and miRNA Analysis of Psoriatic Skin.
Forum for Nordic Dermato-Venereology
Sammendrag/abstract
-
Larose, Tricia L;
Sætrom, Pål;
Martinussen, Marit;
Skogseth, Haakon;
Sandanger, Torkjel M;
Scélo, Ghislaine.
(2019)
In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol.
Journal of Public Health Research
Vitenskapelig artikkel
-
Mjelle, Robin;
Sjursen, Wenche;
Thommesen, Liv;
Sætrom, Pål;
Hofsli, Eva.
(2019)
Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location.
BMC Cancer
Vitenskapelig artikkel
-
Zhao, Xiaoyang;
Reebye, Vikash;
Hitchen, Paul;
Fan, Jia;
Jiang, Hongchi;
Sætrom, Pål.
(2019)
Mechanisms involved in the activation of C/EBP? by small activating RNA in hepatocellular carcinoma.
Oncogene
Vitenskapelig artikkel
-
Kroustallaki, Pinelopi;
Lirussi, Lisa;
Carracedo Huroz, Sergio;
You, Panpan;
Esbensen, Qin Ying;
Götz, Alexandra.
(2019)
SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing.
Cell reports
Vitenskapelig artikkel
-
Mjelle, Robin;
Dima, Simona O;
Bacalbasa, Nicolae;
Chawla, Konika;
Sorop, Andrei;
Cucu, Dana.
(2019)
Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients.
BMC Cancer
Vitenskapelig artikkel
-
Montaldo, Nicola Pietro;
Bordin, Diana Lilian;
Brambilla, Alessandro;
Rösinger, Marcel;
Martin, Sarah Fordyce;
Bjørås, Karine Øian.
(2019)
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression.
Nature Communications
Vitenskapelig artikkel
-
Stovner, Endre Bakken;
Sætrom, Pål.
(2019)
epic2 efficiently finds diffuse domains in ChIP-seq data .
Bioinformatics
Vitenskapelig artikkel
-
Brian, Ben F;
Jolicoeur, Adrienne S;
Guerrero, Candace R.;
Nunez, Myra G;
Sychev, Zoi E;
Hegre, Siv Anita.
(2019)
Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells.
eLIFE
Vitenskapelig artikkel
-
Reebye, Vikash;
Huang, Kai-Wen;
Lin, Vivian;
Jarvis, Sheba;
Cutilas, Pedro;
Dorman, Stephanie.
(2018)
Gene activation of CEBPA using saRNA: Preclinical studies of the first in human saRNA drug candidate for liver cancer.
Oncogene
Vitenskapelig artikkel
-
de rie, D;
Abugesaissa, I;
Alam, T;
Arner, E;
Ashoor, H;
Åström, G.
(2017)
An integrated expression atlas of miRNAs and their promoters in human and mouse.
Nature Biotechnology
Vitenskapelig artikkel
-
Voutila, Jon;
Reebye, Vikash;
Roberts, Thomas C.;
Protopapa, Pantelitsa;
Andrikakou, Pinelopi;
Blakey, David C..
(2017)
Development and mechanism of small activating RNA targeting CEBPA, a novel therapeutic in clinical trials for liver cancer.
Molecular Therapy
Vitenskapelig artikkel
-
Olsen, Maria Belland;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Vinge, Leif Erik;
Alfsnes, Katrine;
Palibrk, Vuk.
(2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.
Cell reports
Vitenskapelig artikkel
-
Olsen, Lene Christin;
O'Reilly, Kally;
Liabakk, Nina-Beate;
Witter, Menno;
Sætrom, Pål.
(2017)
MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex.
Brain Structure and Function
Vitenskapelig artikkel
-
Skogholt, Anne Heidi;
Ryeng, Einar;
Erlandsen, Sten Even;
Skorpen, Frank;
Arentz Schønberg, Svanhild Margrethe;
Sætrom, Pål.
(2017)
Gene expression differences between PAXgene and Tempus blood RNA tubes are highly reproducible between independent samples and biobanks.
BMC Research Notes
Vitenskapelig artikkel
-
Mjelle, Robin;
Sellæg, Kjersti;
Sætrom, Pål;
Thommesen, Liv;
Sjursen, Wenche;
Hofsli, Eva.
(2017)
Identification of metastasis-associated microRNAs in serum from rectal cancer patients.
OncoTarget
Vitenskapelig artikkel
-
Landfors, Miriam;
Johansen, Jostein;
Aronsen, Jan Magnus;
Vågbø, Cathrine Broberg;
Doré, Louis C.;
He, Chuan.
(2017)
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation.
Cell Discovery
Vitenskapelig artikkel
-
Yoon, Sorah;
Huang, Kai-Wen;
Reebye, Vikash;
Mintz, Paul;
Tien, Yu-Wen;
Lai, Hong-Shiee.
(2016)
Targeted Delivery of C/EBPα -saRNA by Pancreatic Ductal Adenocarcinoma-specific RNA Aptamers Inhibits Tumor Growth in Vivo.
Molecular Therapy
Vitenskapelig artikkel
-
Stracquadanio, Giovanni;
Wang, Xuting;
Wallace, Marsha D;
Grawenda, Anna M.;
Zhang, Ping;
Hewitt, Juliet.
(2016)
The importance of p53 pathway genetics in inherited and somatic cancer genomes.
Nature Reviews Cancer
Vitenskapelig artikkel
-
Langkilde, Ane;
Olsen, Lene Christin;
Sætrom, Pål;
Drabløs, Finn Sverre;
Besenbacher, Søren;
Raaby, Line.
(2016)
Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α.
PLOS ONE
Vitenskapelig artikkel
-
Robles, Ana I.;
Olsen, Karina Standahl;
Tsui, Dana W.T.;
Georgoulias, Vassilis;
Creaney, Jenette;
Dobra, Katalin.
(2016)
Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway.
Journal of Translational Medicine
Vitenskapelig artikkel
-
Røe, Oluf Dimitri;
Mjelle, Robin;
Sætrom, Pål;
Andreassen, Trygve;
Bathen, Tone Frost;
Hveem, Kristian.
(2016)
Serum microRNAs/enriched pathways in lung cancer 1-4 years before diagnosis: A pilot study from the HUNT Biobank, Norway.
Journal of Clinical Oncology
Sammendrag/abstract
-
Achar, Avinash;
Sætrom, Pål.
(2015)
RNA motif discovery: a computational overview.
Biology Direct
Vitenskapelig oversiktsartikkel/review
-
Simpson, Melanie Rae;
Brede, Gaute;
Johansen, Jostein;
Johnsen, Roar;
Storrø, Ola;
Sætrom, Pål.
(2015)
Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis in offspring.
PLOS ONE
Vitenskapelig artikkel
-
Pettersen, Henrik Sahlin;
Galashevskaya, Anastasia;
Doseth, Berit;
Sousa, Mirta;
Sarno, Antonio;
Visnes, Torkild.
(2015)
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.
DNA Repair
Vitenskapelig artikkel
-
Hansen, Maren Fridtjofsen;
Johansen, Jostein;
Bjørnevoll, Inga;
Sylvander, Anna Elisabeth;
Steinsbekk, Kristin Solum;
Sætrom, Pål.
(2015)
A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine.
Familial Cancer
Vitenskapelig artikkel
-
Mjelle, Robin;
Hegre, Siv Anita;
Aas, Per Arne;
Slupphaug, Geir;
Drabløs, Finn;
Sætrom, Pål.
(2015)
Cell cycle regulation of human DNA repair and chromatin remodeling genes.
DNA Repair
Vitenskapelig artikkel
-
Hansen, Maren Fridtjofsen;
Johansen, Jostein;
Bjørnevoll, Inga;
Sylvander, Anna Elisabeth;
Steinsbekk, Kristin Solum;
Sætrom, Pål.
(2015)
A novel POLE variant, identified by exome sequencing, causes colorectal- and extra-colonic cancers.
Familial Cancer
Sammendrag/abstract
-
Razick, Sabry;
Mocnik, Rok;
Thomas, Laurent;
Ryeng, Einar;
Drabløs, Finn;
Sætrom, Pål.
(2014)
The eGenVar data management system--cataloguing and sharing sensitive data and metadata for the life sciences.
Database: The Journal of Biological Databases and Curation
Vitenskapelig artikkel
-
Reddy, MA;
Chen, Z;
Park, JT;
Wang, M;
Lanting, L;
Zhang, Q.
(2014)
Regulation of inflammatory phenotype in macrophages by a diabetes-induced long noncoding RNA.
Diabetes
Vitenskapelig artikkel
-
Krokan, Hans Einar;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Kavli, Bodil Merete;
Slupphaug, Geir.
(2014)
Error-free versus mutagenic processing of genomic uracil-Relevance to cancer.
DNA Repair
Vitenskapelig artikkel
-
Lange, LA;
Hu, Y;
Zhang, H;
Xue, C;
Schmidt, EM;
Tang, ZZ.
(2014)
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
American Journal of Human Genetics
Vitenskapelig artikkel
-
Mintz, PJ;
Huang, KW;
Reebye, V;
Nteliopoulos, G;
Lai, HS;
Sætrom, Pål.
(2014)
Exploiting Human CD34(+) Stem Cell-conditioned Medium for Tissue Repair.
Molecular Therapy
Vitenskapelig artikkel
-
Reebye, V;
Sætrom, Pål;
Mintz, PJ;
Huang, KW;
Swiderski, P;
Peng, L.
(2014)
A Novel RNA Oligonucleotide Improves Liver Function and Inhibits Liver Carcinogenesis In Vivo.
Hepatology
Vitenskapelig artikkel
-
Thomas, Laurent;
Sætrom, Pål.
(2014)
Circular RNAs are depleted of polymorphisms at microRNA binding sites.
Bioinformatics
Vitenskapelig artikkel
-
Johnsen, Ingvild Bjellmo;
Løvstakken, Lasse;
Åsvold, Bjørn Olav;
Høydal, Morten;
Sætrom, Pål;
Bonnevie, Tora.
(2014)
NTNUs stjerneforskere.
Adresseavisen
Intervju tidsskrift
-
Leung, A;
Trac, C;
Jin, W;
Lanting, L;
Akbany, A;
Sætrom, Pål.
(2013)
Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells.
Circulation Research
Vitenskapelig artikkel
-
Sætrom, Pål.
(2013)
Designing dual-targeting siRNA duplexes having two active strands that combine siRNA and microRNA-like targeting.
Methods in molecular biology
Vitenskapelig artikkel
-
Hegre, Siv Anita;
Sætrom, Pål;
Aas, Per Arne;
Pettersen, Henrik P Sahlin;
Otterlei, Marit;
Krokan, Hans Einar.
(2013)
Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase.
DNA Repair
Vitenskapelig artikkel
-
Diaz, Javier Pena;
Hegre, Siv Anita;
Anderssen, Endre;
Aas, Per Arne;
Mjelle, Robin;
Gilfillan, Gregor Duncan.
(2013)
Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Chavali, Sreenivas;
Bruhn, Sören;
Tiemann, Katrin;
Sætrom, Pål;
Barrenäs, Fredrik;
Saito, Takaya.
(2013)
MicroRNAs act complementarily to regulate disease-related mRNA modules in human diseases.
RNA: A publication of the RNA Society
Vitenskapelig artikkel
-
Reebye, Vikash;
Sætrom, Pål;
Mintz, Paul J;
Rossi, JJ;
Kasahara, Noriyuki;
Nteliopoulos, G.
(2013)
A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells.
Molecular Therapy Nucleic Acids
Vitenskapelig artikkel
-
Sjögren, A.-K.M.;
Barrenäs, Fredrik;
Muraro, Antonella;
Gustafsson, M;
Sætrom, Pål;
Wang, H.
(2012)
Monozygotic twins discordant for intermittent allergic rhinitis differ in mRNA and protein levels.
Allergy. European Journal of Allergy and Clinical Immunology
Vitenskapelig artikkel
-
Thomas, Laurent;
Sætrom, Pål.
(2012)
Single Nucleotide Polymorphisms Can Create Alternative Polyadenylation Signals and Affect Gene Expression through Loss of MicroRNA-Regulation.
PLoS Computational Biology
Vitenskapelig artikkel
-
Mintz, Paul J;
Sætrom, Pål;
Reebye, Vikash;
Lundbæk, Marie Benner;
Lao, Kaiqin;
Rossi, John J.
(2012)
MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood.
Molecular Therapy Nucleic Acids
Vitenskapelig artikkel
-
Voutila, J;
Sætrom, Pål;
Mintz, Paul J;
Sun, Guihua;
Alluin, Jessica;
Rossi, JJ.
(2012)
Gene expression profile changes after short-activating RNA-mediated induction of endogenous pluripotency factors in human mesenchymal stem cells.
Molecular Therapy Nucleic Acids
Vitenskapelig artikkel
-
Saito, Takaya;
Sætrom, Pål.
(2012)
Target gene expression levels and competition between transfected and endogenous microRNAs are strong confounding factors in microRNA high-throughput experiments.
Silence
Vitenskapelig artikkel
-
Håndstad, Tony;
Rye, Morten Beck;
Mocnik, Rok;
Drabløs, Finn;
Sætrom, Pål.
(2012)
Cell-type specificity of ChIP-predicted transcription factor binding sites.
BMC Genomics
Vitenskapelig artikkel
-
Rye, Morten Beck;
Sætrom, Pål;
Drabløs, Finn.
(2011)
A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Rye, Morten Beck;
Sætrom, Pål;
Håndstad, Tony;
Drabløs, Finn.
(2011)
Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements.
BMC Biology
Vitenskapelig artikkel
-
Lundbæk, Marie Benner;
Sætrom, Pål.
(2011)
Unconventional RNA interference – recent approaches to robust RNAi.
European Pharmaceutical Review
Fagartikkel
-
Håndstad, Tony;
Rye, Morten Beck;
Drabløs, Finn;
Sætrom, Pål.
(2011)
A ChIP-Seq Benchmark Shows That Sequence Conservation Mainly Improves Detection of Strong Transcription Factor Binding Sites.
PLOS ONE
Vitenskapelig artikkel
-
Thomas, Laurent;
Saito, Takaya;
Sætrom, Pål.
(2011)
Inferring causative variants in microRNA target sites.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Saito, Takaya;
Sætrom, Pål.
(2010)
A two-step site and mRNA-level model for predicting microRNA targets.
BMC Bioinformatics
Vitenskapelig artikkel
-
Saito, Takaya;
Sætrom, Pål.
(2010)
MicroRNAs – targeting and target prediction.
New Biotechnology
Vitenskapelig oversiktsartikkel/review
-
Ehsani, A;
Sætrom, Pål;
Zhang, J;
Alluin, J;
Li, HT;
Snøve, Ola.
(2010)
Rational Design of Micro-RNA-like Bifunctional siRNAs Targeting HIV and the HIV Coreceptor CCR5.
Molecular Therapy
Vitenskapelig artikkel
-
Tiemann, Katrin;
Höhn, Britta;
Ehsani, Ali;
Forman, Stephen J.;
Rossi, John J.;
Sætrom, Pål.
(2010)
Dual-targeting siRNAs.
RNA: A publication of the RNA Society
Vitenskapelig artikkel
-
Matveeva, OV;
Kang, YB;
Spiridonov, AN;
Sætrom, Pål;
Nemtsov, VA;
Ogurtsov, AY.
(2010)
Optimization of Duplex Stability and Terminal Asymmetry for shRNA Design.
PLOS ONE
Vitenskapelig artikkel
-
Sætrom, Pål;
Klein, Joern.
(2009)
miRNA and viral infections in vertebrates.
European Pharmaceutical Review
Vitenskapelig oversiktsartikkel/review
-
Sætrom, Pål;
Biesinger, Jacob;
Li, Sierra M.;
Smith, David;
Thomas, Laurent Francois;
Majzoub, Karim.
(2009)
A Risk Variant in an miR-125b Binding Site in BMPR1B Is Associated with Breast Cancer Pathogenesis.
Cancer Research
Vitenskapelig artikkel
-
Kim, Daniel H.;
S�trom, P�l;
Sn�ve, Ola;
Rossi, John J..
(2008)
MicroRNA-directed transcriptional gene silencing in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Vitenskapelig artikkel
-
Soifer, Harris S.;
Sano, Masayuki;
Sakurai, Kumi;
Chomchan, Pritsana;
S�trom, P�l;
Sherman, Mark A..
(2008)
A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Aagaard, Lars;
Zhang, J;
von Eije, K J;
Li, H;
Saetrom, P;
S�trom, P�l.
(2008)
Engineering and optimization of the miR-106b cluster for ectopic expression of multiplexed anti-HIV RNAs.
Gene Therapy
Vitenskapelig artikkel
-
Lee, N.S.;
Kim, J.S.;
Cho, W.J.;
Lee, M.R.;
Steiner, R.;
Gompers, A..
(2008)
miR-302b maintains "stemness" of human embryonal carcinoma cells by post-transcriptional regulation of Cyclin D2 expression.
Biochemical and Biophysical Research Communications - BBRC
Vitenskapelig artikkel
-
Smith, DD;
Sætrom, Pål;
Snøve, Ola;
Lundberg, C;
Rivas, GE;
Glackin, C.
(2008)
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation.
BMC Bioinformatics
Vitenskapelig artikkel
-
Sætrom, Pål;
Snøve, Ola;
Rossi, John J..
(2007)
Epigenetics and MicroRNAs.
Pediatric Research
Vitenskapelig oversiktsartikkel/review
-
Soifer, Harris S.;
Rossi, John J.;
Sætrom, Pål.
(2007)
MicroRNAs in Disease and Potential Therapeutic Applications.
Molecular Therapy
Vitenskapelig oversiktsartikkel/review
-
Von Eije, KJ;
Aagaard, Lars;
Sætrom, Pål;
Amarzguioui, M;
Li, HT;
Rossi, JJ.
(2007)
Prevention of HIV-1 viral escape upon RNAi treatment: Expression systems that generate multiple anti-HIV siRNAs.
Human Gene Therapy
Sammendrag/abstract
-
Helvik, Snorre Andreas;
Snøve, Ola;
Sætrom, Pål.
(2007)
Reliable prediction of Drosha processing sites improves microRNA gene prediction.
Bioinformatics
Vitenskapelig artikkel
-
Sætrom, Pål;
Snøve, Ola.
(2007)
Robust machine learning algorithms predict microRNA genes and targets.
Methods in Enzymology
Vitenskapelig artikkel
-
Håndstad, Tony;
Hestnes, Arne Johan Husebø;
Sætrom, Pål.
(2007)
Motif kernel generated by genetic programming improves remote homology and fold detection.
BMC Bioinformatics
Vitenskapelig artikkel
-
Matveeva, Olga;
Nechipurenko, Yury;
Rossi, Leo;
Moore, Barry;
Sætrom, Pål;
Ogurtsov, Aleksey Y..
(2007)
Comparison of approaches for rational siRNA design leading to a new efficient and transparent method.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Sætrom, Pål;
Heale, Bret S.;
Snøve, Ola;
Aagaard, Lars;
Alluin, Jessica;
Rossi, John J..
(2007)
Distance constraints between microRNA target sites dictate efficacy and cooperativity.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Snøve, Ola;
Sætrom, Pål.
(2006)
Nobelpris for RNA-interferens.
Tidsskrift for Den norske legeforening
Leder
-
Helvik, Snorre Andreas;
Snøve, Ola;
Sætrom, Pål.
(2006)
Reliable prediction of Drosha processing sites improves microRNA gene prediction.
Bioinformatics
Vitenskapelig artikkel
-
Birkeland, Olaf René;
Snøve, Ola;
Halaas, Arne;
Nedland, Magnar;
Sætrom, Pål.
(2006)
The petacomp Machine - A MIMD Cluster for parallel pattern-mining.
Proceedings IEEE International Conference on Cluster Computing
Vitenskapelig artikkel
Del av bok/rapport
-
Sarno, Antonio;
Sætrom, Pål;
Kavli, Bodil Merete;
Pettersen, Henrik Sahlin.
(2018)
Genomic Uracil and Cancer.
World Scientific
Faglig kapittel
-
Lundbæk, Marie B;
Sætrom, Pål.
(2013)
RNAi Screening and Assays.
John Wiley & Sons
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
-
Snøve, Ola;
Sætrom, Pål.
(2009)
Animal MicroRNA gene prediction.
CRC Press
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
-
Sætrom, Pål;
Snøve, Ola.
(2007)
Machine learning predicts microRNA target sites.
Cambridge University Press
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
-
Sætrom, Pål;
Birkeland, Olaf René;
Snøve, Ola.
(2007)
Boosting Improves Stability and Accuracy of Genetic Programming in Biological Sequence Classification.
Springer
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
Rapport
-
Sætrom, Pål.
(2007)
Hardware accelerated genetic programming for pattern mining in strings.
Doktoravhandlinger ved NTNU (197)
Doktorgradsavhandling
-
Sætrom, Pål.
(2005)
Hardware accelerated genetic programming for pattern mining in strings.
Doktoravhandlinger ved NTNU (2005:197)
Doktorgradsavhandling
PRODUKT
-
Razick, Sabry;
Sætrom, Pål.
(2014)
The eGenVar Data Management System.
Programvare
Undervisning
Emner
Formidling
2023
-
PosterAndersson-Rusch, Clara Leticia; Quist-Løkken, Ingrid; Sætrom, Pål; Beisvag, Vidar; Rolinski, Milosz; Møen, Johanna. (2023) Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma. American Society of Hematology 65th ASH Annual Meeting and Exposition 2023-12-09 - 2023-12-12
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PosterBösl, Korbinian; Bianchini, Federico; Fatima, Nazeefa; Keyvani, Pedram A; Kalhovd, Siri; Tekle, Kidane M. (2023) End-to-end data management tool assembly for Norwegian life scientist. ELIXIR ELIXIR All Hands 2023 , Dublin 2023-06-06 -
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PosterLund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; O'Reilly, Kally; Witter, Menno Peter; Sætrom, Pål. (2023) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. EMBO Gene Regulatory Mechanisms in Neural Fate Decisions , Alicante, Spain 2023-09-07 - 2023-09-10
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Vitenskapelig foredragHaslene-Hox, Hanne; Chahal, Aman Singh; Arlov, Øystein; Øynebråten, Ingrid Ryge; Zaytseva-Zotova, Daria; Vikenes, Anette. (2023) Alginate hydrogel characteristics regulate fibroblast biology. Norsk Biokjemisk selskap Norsk Biokjemisk selskaps kontaktmøte 2023 , Storefjell 2023-01-19 - 2023-01-22
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PosterZaytseva-Zotova, Daria; Haslene-Hox, Hanne; Arlov, Øystein; Hoel, Andrea Draget; Mjelle, Robin; Strand, Wenche. (2023) Alginate hydrogel characteristics regulate NHDF biology. ESB European Society for Biomaterials , Davos, Switzerland 2023-09-03 - 2023-09-08
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PosterStrand, Berit Løkensgard; Haslene-Hox, Hanne; Sætrom, Pål; Zaytseva-Zotova, Daria; Mjelle, Robin; Arlov, Øystein. (2023) Alginate hydrogel characteristics regulate NHDF biology. Scandinavian Society of Biomaterials ScSB 2023 , Røros, Norway 2023-03-21 - 2023-08-24
2022
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PosterNøst, Therese Haugdahl; Urbarova, Ilona Halva; Skogholt, Anne Heidi; Mjelle, Robin; Paulsen, Erna Elise; Dønnem, Tom. (2022) Increased levels of mRNAs and miRNAs associated with imminent and advanced lung cancer. The International Association for the Study of Lung Cancer IASLC 2022 World Conference on Lung Cancer , Wien 2022-08-06 - 2022-08-09
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Faglig foredragChahal, Aman S; Strand, Berit Løkensgard; Haslene-Hox, Hanne; Sætrom, Pål. (2022) An out of body experience: Cell culture in 3D. Digital Life Norway Forskning for folket , Trondheim 2022-10-19 - 2022-10-19
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PosterLund-Hanssen, Charlotte; Olsen, Lene Christin; Thomas, Laurent Francois; Sætrom, Pål. (2022) The Conserved Expression of Long Non-Coding RNAs in the Entorhinal Cortex During Postnatal Development. NORBIS, MedBioInfo 8th Annual NORBIS Conference , Rosendal, Norway 2022-10-24 - 2022-10-28
2021
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Vitenskapelig foredragNøst, Therese Haugdahl; Skogholt, Anne Heidi; Mjelle, Robin; Grønberg, Bjørn Henning; Sandanger, Torkjel M; Sætrom, Pål. (2021) microRNA levels in serum at diagnosis are predictive for lung cancer. Kreftforeningen, Nasjonal ekspertgruppe for lungekreftforskning Forskningskonferansen for Kreftforeningens nasjonale ekspertgruppe for lungekreftforskning , Gardermoen 2021-08-26 - 2021-08-27
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Vitenskapelig foredragKonstantinidis, Ioannis; Sætrom, Pål; Brieuc, Marine Servane Ono; Jakobsen, Kjetill Sigurd; Liedtke, Hannes; Pohlmann, Caroline. (2021) DNA hydroxymethylation is linked to higher growth rate in Nile tilapia. X FIRMA 2021 2021-02-07 - 2021-02-12
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Vitenskapelig foredragKonstantinidis, Ioannis; Sætrom, Pål; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira. (2021) Differences in liver DNA hydroxymethylation reflect the growth phenotype. 6th Genomics in Aquaculture Symposium 2021-05-05 - 2021-05-07
2019
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Vitenskapelig foredragSolvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. The 34th Nordic Congress of Dermatology & Venereology , Gøteborg 2019-05-08 - 2019-05-10
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Faglig foredragZaytseva-Zotova, Daria; Ruohola, Rita; Strand, Wenche Iren; Akbarzadeh, Anita; Haslene-Hox, Hanne; Arlov, Øystein. (2019) Alginate hydrogels with tailored mechanical and biological properties for 3D fibroblast culture . DigitalLife 2019 2019-09-05 - 2019-09-06
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PosterSolvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin. European Society for Dermatological Research European Society for Dermatological Research Annual Meeting , Bordeaux 2019-09-18 - 2019-09-21
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PosterLøset, Mari; Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita. (2019) Differentially Expressed miRNAs and mRNAs in Psoriatic Skin . American Society for Human Genetics American Society for Human Genetics Annual Meeting , Houston, TX 2019-10-15 - 2019-10-19
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PosterSkogholt, Anne Heidi; Jensen, Espen Drevland; Ryeng, Einar; Grønberg, Bjørn Henning; Skorpen, Frank; Schønberg, Svanhild Margrethe Arentz. (2019) Robust messenger RNA (mRNA) markers in blood for lung cancer diagnosis. ASHG , Houston 2019-10-18 - 2019-10-18
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Vitenskapelig foredragKonstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2019) Tissue-specific hydroxymethylome profiles of Nile tilapia Oreochromis niloticus at single nucleotide resolution. Aquaculture 2019 2019-03-07 - 2019-03-11
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PosterSamdal, Helle; Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2019) Functional evaluation of long non-coding RNAs with potential roles during cell replication. Keystone symposia on molecular and cellular biology Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics , Whistler 2019-02-24 - 2019-02-28
2018
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PosterBlankvoort, Stefan; Thomas, Laurent; Witter, Menno; Sætrom, Pål; cotney, Justin; Kentros, Clifford. (2018) The marked diversity of unique cortical enhancers enables neuron-specific tools by Enhancer-Driven Gene Expression (EDGE). Federation of European Neuroscience FENS 2018 , Berlin 2018-07-07 - 2018-07-11
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PosterHalaas, Øyvind; Sætrom, Pål; Arlov, Øystein; Haslene-Hox, Hanne; Beisvag, Vidar; Aachmann, Finn Lillelund. (2018) 3DLife – Emulating life in 3D with digital and experimental tissue models. Digital Life Norway DigitalLife 2018 , Bergen 2018-03-20 - 2018-03-21
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PosterHegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Samdal, Helle; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2018) Long non-coding RNAs in epigenetic inheritance. Keystone Symposia on Molecular and Cellular Biology Noncoding RNAs: Form, Function, Physiology , Keystone, Colorado 2018-02-25 - 2018-03-01
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PosterOlsen, Lene Christin; Sætrom, Pål; Witter, Menno. (2018) Detecting early molecular events in a mouse model of Alzheimer’s disease (AD) using single cell RNA sequencing. NORBIS NORBIS annual conference , Voss 2018-10-17 - 2018-10-19
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Vitenskapelig foredragKonstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira. (2018) Fast muscle hydroxymethylation patterns in wild and captive Nile tilapia (Oreochromis niloticus) provide insights into fish domestication. GIA2018: 5th International Symposium on Genomics in Aquaculture , Albufeira 2018-03-21 - 2018-03-23
2017
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PosterHegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin; Aas, Per Arne. (2017) Long non-coding RNAs in epigenetic inheritance * Won Poster prize of 250 EUR at the EMBO|EMBL Symposium. EMBL EMBO EMBL Symposium "The Non-Coding genome" , Heidelberg 2017-09-13 - 2017-09-16
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PosterHegre, Siv Anita; Klima, Antonin; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-Analysis of RNA expression identifies human cell-cycle genes. Keystone Symposia Keystone Symposia "Noncoding RNAs: From Disease to Targeted Therapeutics" , Banff 2017-02-05 -
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PosterHegre, Siv Anita; Stovner, Endre Bakken; Sætrom, Pål. (2017) Find diffusely enriched chromatin domains in ChIP-seq data with epic. Keystone Symposia Keystone Symposia "Noncoding RNAs: From disease to targeted therapeutics" , Banff 2017-02-05 - 2017-02-09
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Faglig foredragKonstantinidis, Ioannis; Fernandes, Jorge Manuel de Oliveria; Sætrom, Pål. (2017) The first hydroxymethylation map of fast muscle in Nile tilapia (Oreochromis niloticus). European Aquaculture Society Aquaculture Europe 2017 , Dubrovnik 2017-10-17 - 2017-10-20
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PosterKlima, Antonin; Hegre, Siv Anita; Aas, Per Arne; Liabakk, Nina-Beate; Sætrom, Pål. (2017) Meta-analysis of RNA expression identifies human cell-cycle genes. Norbis – Annual National Conference 2017-11-08 - 2017-11-10
2016
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PosterJohansen, Jostein; Chawla, Konika; Olsen, Lene Christin; Sætrom, Pål. (2016) Bioinformatics Core Facility. NTNU Seminar for staff at the future Faculty of Medicine and Health Sciences , Trondheim 2016-11-10 - 2016-11-11
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Vitenskapelig foredragKrokan, Hans Einar; Kavli, Bodil Merete; Pettersen, Henrik Sahlin; Sætrom, Pål; Galashevskaya, Anastasia; Sarno, Antonio. (2016) Genomic Uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. The 10th International 3R (Replication, recombination and repair) Symposium, Matsue, Japan , Matsue 2016-11-13 - 2016-11-17
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Vitenskapelig foredragKrokan, Hans Einar; Pettersen, Henrik Sahlin; Mjelle, Robin; Hegre, Siv Anita; Sætrom, Pål; Drabløs, Finn Sverre. (2016) REGULATION OF BASE EXCISION REPAIR – CANONICAL AND NON-CANONICAL PROCESSING OF GENOMIC URACIL. Russian Academy of Sciences, Siberian branch 10th International Multiconference on Bioinformatics of Genome Regulation and Structure\Systems Biology , Akademorodok, Novosibirsk 2016-08-29 - 2016-09-03
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Faglig foredragKrokan, Hans Einar; Slupphaug, Geir; Sætrom, Pål; Sarno, Antonio; Galashevskaya, Anastasia; Lundbæk, Marie Benner. (2016) Genomic uracil - Important carcinogenic mutagen but normal intermediate in adaptive immunity. Turkish Society of Toxicology. Eurotox 2016 , Sivilla 2016-09-04 -
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Vitenskapelig foredragKlima, Antonin; Sætrom, Pål. (2016) Transcriptome-Wide Discovery of Cell-Cycle Genes. Norbis – Annual National Conference 2016-09-14 - 2016-09-16
2015
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Vitenskapelig foredragSimpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål. (2015) Human breast milk miRNA, maternal probiotic supplementation and atopic dermatitis (oral presentation). International Milk Genomics Consortium 12th International Symposium on Milk Genomics and Human Health , Sydney 2015-10-26 - 2015-10-28
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PosterSimpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Storrø, Ola; Johnsen, Roar; Sætrom, Pål. (2015) Human breast milk miRNA, maternal probiotics supplementation and atopic dermatitis in offspring (poster). International Milk Genomics Consortium 12th International Symposium on Milk Genomics and Human Health , Sydney 2015-10-26 - 2015-10-28
2014
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Intervju
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Vitenskapelig foredragSætrom, Pål. (2014) Management and Analyses of Population Data on Genetic Variation. 2nd Annual Next Generation Sequencing Data Congress 2014-05-19 - 2014-05-20
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Faglig foredragRazick, Sabry; Sætrom, Pål. (2014) Data advertising and managing platform for biobanks - a use case for the eGenVar data management system. European, Middle Eastern and Afran Society for Biopreservati European, Middle Eastern and Afran Society for Biopreservation & Biobanking , Leipzig 2014-10-21 - 2014-10-24
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Vitenskapelig foredragHansen, Maren Fridtjofsen; Johansen, Jostein; Bjørnevoll, Inga; Sylvander, Anna Elisabeth; Steinsbekk, Kristin Solum; Sætrom, Pål. (2014) Using exome sequencing for identification of high-risk genetic variants in a family predisposed for colorectal cancer. COST Action BM1206 Meeting , Leiden 2014-09-04 - 2014-09-04
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Vitenskapelig foredragSætrom, Pål. (2014) The effect of the core RISC-component Ago2 on microRNA composition and regulation. Illumina Sequencing Seminar 2014-02-13 -
2013
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Vitenskapelig foredragSætrom, Pål; Thomas, Laurent. (2013) Finding SNPs that affect microRNA regulation. 10th International RNAi, MicroRNAs & Single Cell Biology – 2013 Meeting 2013-05-01 - 2013-05-02
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Vitenskapelig foredragSætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is up-regulated during DNA replication. Department of Molecular Biology, University of Bergen Department seminar , Bergen 2013-04-26 - 2013-04-26
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IntervjuSætrom, Pål. (2013) Innebygd klokke måler alder til menneskeleg vev. forskning.no forskning.no [Internett] 2013-10-24
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PosterPena-Diaz, Javier; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Norwegian Biochemical Society Norwegian Biochemical Society Contact Meeting , Lillehammer 2013-01-31 - 2013-02-03
2012
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IntervjuTorheim, Norunn K.; Sætrom, Pål. (2012) Nye verktøy i jakten på sykdomsårsaker. www.forskning.no www.forskning.no [Internett] 2012-05-24
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Populærvitenskapelig foredragSætrom, Pål. (2012) Født sånn eller blitt sånn? Hvordan samvirker gener og miljø. Lions medlemsmøte 2012-03-05 - 2012-03-05
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Vitenskapelig foredragSætrom, Pål. (2012) Epigenetics and the human cell-division cycle. Department seminar 2012-04-25 - 2012-04-25
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Vitenskapelig foredragDrabløs, Finn; Rye, Morten Beck; Klepper, Kjetil; Sætrom, Pål. (2012) Definition and analysis of gene sets from time series data. FANTOM RIKEN FANTOM time-courses meeting , Yokohama 2012-10-29 - 2012-11-02
2011
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Vitenskapelig foredragSætrom, Pål. (2011) Tools for analyzing and designing small RNA-mediated gene regulation. Department of Biology, University of Copenhagen Invited seminar 2011-08-16 - 2011-08-16
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Vitenskapelig foredragSætrom, Pål. (2011) Analyzing and designing small RNA-mediated gene regulation. Bioinformatics for Regulatory Genomics (BioRegSIG) - Special Interest Group (SIG) at Intelligent Systems for Molecular Biology , Wienna 2011-07-16 -
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Vitenskapelig foredragSætrom, Pål. (2011) Handling, integrating, and analysing biobank data in a hypothesis-driven framework. Department of Informatics, University of Oslo Bioinformatics Seminars 2011-09-23 -
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PosterRye, Morten Beck; Drabløs, Finn; Sætrom, Pål; Håndstad, Tony. (2011) Epigenetic Influence on Cell-type specific peaks from ChIP-Seq data. Keystone Symposia Histone code: Fact or fiction? , Midway, Utah 2011-01-10 - 2011-01-15
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PosterRye, Morten Beck; Sætrom, Pål; Håndstad, Tony; Drabløs, Finn. (2011) Clusters of ChIP-Seq defined transcription factor binding sites map regulatory elelemnts in the human genome. Cambridge Research Institute Unanswered Questions in Transcription, Annual international Symposium , Cambridge 2011-11-04 - 2011-11-05
2010
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Vitenskapelig foredragSætrom, Pål. (2010) Bioinformatics of small RNA-mediated gene regulation. Systems Biology meetings at NTNU 2010-10-08 - 2010-10-08
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Vitenskapelig foredragSætrom, Pål. (2010) Epigenetic and microRNA regulation of the cell cycle. Onsdagsmøte IKM 2010-12-01 - 2010-12-01
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Vitenskapelig foredragSætrom, Pål. (2010) Bioinformatics of small RNA-mediated gene regulation. Seminar at Science for Life Laboratory (SciLifeLab) 2010-10-05 - 2010-10-05
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Vitenskapelig foredragSætrom, Pål. (2010) Tools for analyzing and designing small RNA-mediated gene regulation. City of Hope’s Beckman Research Institute seminar series 2010-05-04 - 2010-05-04
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PosterSaito, Takaya; Sætrom, Pål. (2010) Poster presentation: A two-step site and mRNA-level model for predicting microRNA target. Norwegian Radium Hospital / Max Planck Institute RECOMB Computational Cancer Biology , Oslo 2010-06-24 - 2010-06-25
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PosterThomas, Laurent Francois; Saito, Takaya; Sætrom, Pål. (2010) Identifying causative variants in microRNA target sites. Norwegian Radium Hospital / University of Oslo RECOMB Computational Cancer Biology , Oslo 2010-06-24 - 2010-06-25
2009
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Vitenskapelig foredragSætrom, Pål. (2009) Synergistic regulation by microRNAs. Third Bertinoro Systems Biology Workshop , Bertinoro 2009-03-29 - 2009-04-03
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PosterHegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Olsen, Lene Christin; Lundbæk, Marie Benner; Diaz, Javier Pena. (2009) Multiple microRNAs appear to regulate the DNA repair enzyme UNG2 during the cell cycle. Keystone Symposia MicroRNA and Cancer Conference , Keystone, Colorado 2009-06-10 - 2009-06-15
2008
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Vitenskapelig foredragS�trom, P�l. (2008) Cooperative microRNA Targeting and Regulation – Applications in siRNA Design. NMC Møte , Selbu 2008-11-24 - 2008-11-25
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Vitenskapelig foredragSætrom, Pål. (2008) Synergistic microRNA-like targeting by short interfering RNAs can give robust HIV-inhibition. Joint Centre for Bioinformatics in Oslo, UiO Bioinformatics Wednesday seminars , Oslo 2008-12-03 - 2008-12-03
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Vitenskapelig foredragSætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Norwegian Bioinformatics Forum 2008 , Bergen 2008-10-09 - 2008-10-10
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Vitenskapelig foredragSætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Bioinformatics-meeting 2008 2008-09-30 - 2008-09-30
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Vitenskapelig foredragSætrom, Pål. (2008) Gene regulation by microRNAs and microRNA regulation of DNA repair. Genes, Genomes and Evolution: Structure and Hyperstructure , Geiranger 2008-08-12 - 2008-08-16
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Vitenskapelig foredragSætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. RNAi Europe , Stockholm 2008-09-16 - 2008-09-18
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Vitenskapelig foredragSætrom, Pål. (2008) Cooperative microRNA Targeting and Regulation. Current Topics in RNA Biology 2008-09-27 - 2008-09-29
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Populærvitenskapelig foredragSætrom, Pål. (2008) Små RNA - viktige i sykdom og lovende terapeutiske kandidater. Norges forskningsråd Sluttrapporteringsseminar for FUGE , Oslo 2008-05-21 - 2008-05-21
2007
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Vitenskapelig foredragSætrom, Pål. (2007) The roles of microRNAs and transcription factors in gene regulation and tissue specific expression. Department of Biomedicine, University of Bergen BBB Seminars - The BioMedical and BioSciences Lecture Series , Bergen 2007-09-20 - 2007-09-20
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Vitenskapelig foredragSætrom, Pål. (2007) Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity. GeneExpression Systems (USA), University of Cambridge (UK) MicroRNAs Europe 2007 Meeting on MicroRNAs: Biology to Development and Disease , Cambridge 2007-11-01 - 2007-11-02
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Vitenskapelig foredragSætrom, Pål. (2007) Cooperative microRNA targeting and robust inhibition of HIV. siRNAsense 2nd RNA Interference Conference , Oslo 2007-05-14 - 2007-05-14
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Vitenskapelig foredragSætrom, Pål; Heale, Bret S.; Snøve, Ola; Aagaard, Lars; Alluin, Jessica; Rossi, John J.. (2007) Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity. RNA 2007 - Twelfth Annual Meeting of the RNA Society , Madison, WI 2007-05-29 - 2007-06-03
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Vitenskapelig foredragSætrom, Pål. (2007) The roles of microRNAs and transcription factors in gene regulation and tissue specific expression. FUGE Midt-Norge FUGE seminar , Trondheim 2007-12-17 - 2007-12-17
2006
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Vitenskapelig foredragSætrom, Pål; Birkeland, Olaf René; Snøve, Ola. (2006) Boosting improves stability and accuracy of genetic programming in biological sequence classification. University of Michigan Genetic Programming Theory and Practice IV , Ann Arbor 2006-05-11 - 2006-05-13
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Vitenskapelig foredragSætrom, Pål. (2006) Predicting microRNA targets - challenges and solutions. Society for Bioinformatics in the Nordic Countries (SocBiN) Bioinformatics 2006 , Århus 2006-06-15 - 2006-06-18