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Pål Sætrom bruker datamodeller for å studere hvordan endringer i genregulering kan kontrollere utvikling og forårsake sykdom. See the English version for details.

Publikasjoner

Vitenskapelig, faglig og kunstnerisk arbeid

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Tidsskriftspublikasjoner

  • Baiju, Nikita; Sandanger, Torkjel M; Sætrom, Pål; Nøst, Therese Haugdahl. (2021) Gene expression in blood reflects smoking exposure among cancer-free women in the Norwegian Women and Cancer (NOWAC) postgenome cohort. Scientific Reports. vol. 11 (1).
  • Grapotte, Mathys; Saraswat, Manu; Bessière, Chloé; Menichelli, Christophe; Ramilowski, Jordan A.; Severin, Jessica; Hayashizaki, Yoshihide; Itoh, Masayoshi; Tagami, Michihira; Murata, Mitsuyoshi; Kojima-Ishiyama, Miki; Noma, Shohei; Noguchi, Shuhei; Kasukawa, Takeya; Hasegawa, Akira; Suzuki, Harukazu; Nishiyori-Sueki, Hiromi; Frith, Martin C.; Abugessaisa, Imad; Aitken, Stuart; Aken, Bronwen L.; Alam, Intikhab; Alam, Tanvir; Alasiri, Rami; Alhendi, Ahmad M. N.; Alinejad-Rokny, Hamid; Alvarez, Mariano J.; Andersson, Robin; Arakawa, Takahiro; Araki, Marito; Arbel, Taly; Archer, John; Archibald, Alan L.; Arner, Erik; Arner, Peter; Asai, Kiyoshi; Ashoor, Haitham; Astrom, Gaby; Babina, Magda; Baillie, J. Kenneth; Bajic, Vladimir B.; Bajpai, Archana; Baker, Sarah; Baldarelli, Richard M.; Balic, Adam; Bansal, Mukesh; Batagov, Arsen O.; Batzoglou, Serafim; Beckhouse, Anthony G.; Beltrami, Antonio P.; Beltrami, Carlo A.; Bertin, Nicolas; Bhattacharya, Sharmodeep; Bickel, Peter J.; Blake, Judith A.; Blanchette, Mathieu; Bodega, Beatrice; Bonetti, Alessandro; Bono, Hidemasa; Bornholdt, Jette; Bttcher, Michael; Bougouffa, Salim; Boyd, Mette; Breda, Jeremie; Brombacher, Frank; Brown, James B.; Bult, Carol J.; Burroughs, A. Maxwell; Burt, Dave W.; Busch, Annika; Caglio, Giulia; Califano, Andrea; Cameron, Christopher J.; Cannistraci, Carlo V.; Carbone, Alessandra; Carlisle, Ailsa J.; Carninci, Piero; Carter, Kim W.; Cesselli, Daniela; Chang, Jen-Chien; Chen, Julie C.; Chen, Yun; Chierici, Marco; Christodoulou, John; Ciani, Yari; Clark, Emily L.; Coskun, Mehmet; Dalby, Maria; Dalla, Emiliano; Daub, Carsten O.; Davis, Carrie A.; de Hoon, Michiel J. L.; de Rie, Derek; Denisenko, Elena; Deplancke, Bart; Detmar, Michael; Deviatiiarov, Ruslan; Di Bernardo, Diego; Diehl, Alexander D.; Dieterich, Lothar C.; Dimont, Emmanuel; Djebali, Sarah; Dohi, Taeko; Dostie, Jose; Drabløs, Finn; Edge, Albert S. B.; Edinger, Matthias; Ehrlund, Anna; Ekwall, Karl; Elofsson, Arne; Endoh, Mitsuhiro; Enomoto, Hideki; Enomoto, Saaya; Faghihi, Mohammad; Fagiolini, Michela; Farach-Carson, Mary C.; Faulkner, Geoffrey J.; Favorov, Alexander; Fernandes, Ana Miguel; Ferrai, Carmelo; Forrest, Alistair R. R.; Forrester, Lesley M.; Forsberg, Mattias; Fort, Alexandre; Francescatto, Margherita; Freeman, Tom C.; Frith, Martin; Fukuda, Shinji; Funayama, Manabu; Furlanello, Cesare; Furuno, Masaaki; Furusawa, Chikara; Gao, Hui; Gazova, Iveta; Gebhard, Claudia; Geier, Florian; Geijtenbeek, Teunis B. H.; Ghosh, Samik; Ghosheh, Yanal; Gingeras, Thomas R.; Gojobori, Takashi; Goldberg, Tatyana; Goldowitz, Daniel; Gough, Julian; Greco, Dario; Gruber, Andreas J.; Guhl, Sven; Guigo, Roderic; Guler, Reto; Gusev, Oleg; Gustincich, Stefano; Ha, Thomas J.; Haberle, Vanja; Hale, Paul; Hallstrom, Bjrn M.; Hamada, Michiaki; Handoko, Lusy; Hara, Mitsuko; Harbers, Matthias; Harrow, Jennifer; Harshbarger, Jayson; Hase, Takeshi; Hasegawa, Akira; Hashimoto, Kosuke; Hatano, Taku; Hattori, Nobutaka; Hayashi, Ryuhei; Hayashizaki, Yoshihide; Herlyn, Meenhard; Hettne, Kristina; Heutink, Peter; Hide, Winston; Hitchens, Kelly J.; Sui, Shannon Ho; ’t Hoen, Peter A. C.; Hon, Chung Chau; Hori, Fumi; Horie, Masafumi; Horimoto, Katsuhisa; Horton, Paul; Hou, Rui; Huang, Edward; Huang, Yi; Hugues, Richard; Hume, David; Ienasescu, Hans; Iida, Kei; Ikawa, Tomokatsu; Ikemura, Toshimichi; Ikeo, Kazuho; Inoue, Norihiko; Ishizu, Yuri; Ito, Yosuke; Itoh, Masayoshi; Ivshina, Anna V.; Jankovic, Boris R.; Jenjaroenpun, Piroon; Johnson, Rory; Jorgensen, Mette; Jorjani, Hadi; Joshi, Anagha; Jurman, Giuseppe; Kaczkowski, Bogumil; Kai, Chieko; Kaida, Kaoru; Kajiyama, Kazuhiro; Kaliyaperumal, Rajaram; Kaminuma, Eli; Kanaya, Takashi; Kaneda, Hiroshi; Kapranov, Philip; Kasianov, Artem S.; Kasukawa, Takeya; Katayama, Toshiaki; Kato, Sachi; Kawaguchi, Shuji; Kawai, Jun; Kawaji, Hideya; Kawamoto, Hiroshi; Kawamura, Yuki I.; Kawasaki, Satoshi; Kawashima, Tsugumi; Kempfle, Judith S.; Kenna, Tony J.; Kere, Juha; Khachigian, Levon; Kiryu, Hisanori; Kishima, Mami; Kitajima, Hiroyuki; Kitamura, Toshio; Kitano, Hiroaki; Klaric, Enio; Klepper, Kjetil; Klinken, S. Peter; Kloppmann, Edda; Knox, Alan J.; Kodama, Yuichi; Kogo, Yasushi; Kojima, Miki; Kojima, Soichi; Komatsu, Norio; Komiyama, Hiromitsu; Kono, Tsukasa; Koseki, Haruhiko; Koyasu, Shigeo; Kratz, Anton; Kukalev, Alexander; Kulakovskiy, Ivan; Kundaje, Anshul; Kunikata, Hiroshi; Kuo, Richard; Kuo, Tony; Kuraku, Shigehiro; Kuznetsov, Vladimir A.; Kwon, Tae Jun; Larouche, Matt; Lassmann, Timo; Law, Andy; Le-Cao, Kim-Anh; Lecellier, Charles-Henri; Lee, Weonju; Lenhard, Boris; Lennartsson, Andreas; Li, Kang; Li, Ruohan; Lilje, Berit; Lipovich, Leonard; Lizio, Marina; Lopez, Gonzalo; Magi, Shigeyuki; Mak, Gloria K.; Makeev, Vsevolod; Manabe, Riichiro; Mandai, Michiko; Mar, Jessica; Maruyama, Kazuichi; Maruyama, Taeko; Mason, Elizabeth; Mathelier, Anthony; Matsuda, Hideo; Medvedeva, Yulia A.; Meehan, Terrence F.; Mejhert, Niklas; Meynert, Alison; Mikami, Norihisa; Minoda, Akiko; Miura, Hisashi; Miyagi, Yohei; Miyawaki, Atsushi; Mizuno, Yosuke; Morikawa, Hiromasa; Morimoto, Mitsuru; Morioka, Masaki; Morishita, Soji; Moro, Kazuyo; Motakis, Efthymios; Motohashi, Hozumi; Mukarram, Abdul Kadir; Mummery, Christine L.; Mungall, Christopher J.; Murakawa, Yasuhiro; Muramatsu, Masami; Murata, Mitsuyoshi; Nagasaka, Kazunori; Nagase, Takahide; Nakachi, Yutaka; Nakahara, Fumio; Nakai, Kenta; Nakamura, Kumi; Nakamura, Yasukazu; Nakamura, Yukio; Nakazawa, Toru; Nason, Guy P.; Nepal, Chirag; Nguyen, Quan Hoang; Nielsen, Lars K.; Nishida, Kohji; Nishiguchi, Koji M.; Nishiyori, Hiromi; Nitta, Kazuhiro; Noguchi, Shuhei; Noma, Shohei; Notredame, Cedric; Ogishima, Soichi; Ohkura, Naganari; Ohno, Hiroshi; Ohshima, Mitsuhiro; Ohtsu, Takashi; Okada, Yukinori; Okada-Hatakeyama, Mariko; Okazaki, Yasushi; Oksvold, Per; Orlando, Valerio; Ow, Ghim Sion; Ozturk, Mumin; Pachkov, Mikhail; Paparountas, Triantafyllos; Parihar, Suraj P.; Park, Sung-Joon; Pascarella, Giovanni; Passier, Robert; Persson, Helena; Philippens, Ingrid H.; Piazza, Silvano; Plessy, Charles; Pombo, Ana; Ponten, Fredrik; Poulain, Stéphane; Poulsen, Thomas M.; Pradhan, Swati; Prezioso, Carolina; Pridans, Clare; Qin, Xiang-Yang; Quackenbush, John; Rackham, Owen; Ramilowski, Jordan; Ravasi, Timothy; Rehli, Michael; Rennie, Sarah; Rito, Tiago; Rizzu, Patrizia; Robert, Christelle; Roos, Marco; Rost, Burkhard; Roudnicky, Filip; Roy, Riti; Rye, Morten Beck; Sachenkova, Oxana; Sætrom, Pål; Sai, Hyonmi; Saiki, Shinji; Saito, Mitsue; Saito, Akira; Sakaguchi, Shimon; Sakai, Mizuho; Sakaue, Saori; Sakaue-Sawano, Asako; Sandelin, Albin; Sano, Hiromi; Sasamoto, Yuzuru; Sato, Hiroki; Saxena, Alka; Saya, Hideyuki; Schafferhans, Andrea; Schmeier, Sebastian; Schmidl, Christian; Schmocker, Daniel; Schneider, Claudio; Schueler, Marcus; Schultes, Erik A.; Schulze-Tanzil, Gundula; Semple, Colin A.; Seno, Shigeto; Seo, Wooseok; Sese, Jun; Severin, Jessica; Sheng, Guojun; Shi, Jiantao; Shimoni, Yishai; Shin, Jay W.; SimonSanchez, Javier; Sivertsson, Asa; Sjostedt, Evelina; Soderhall, Cilla; Laurent, Georges St; Stoiber, Marcus H.; Sugiyama, Daisuke; Summers, Kim M.; Suzuki, Ana Maria; Suzuki, Harukazu; Suzuki, Kenji; Suzuki, Mikiko; Suzuki, Naoko; Suzuki, Takahiro; Swanson, Douglas J.; Swoboda, Rolf K.; Tagami, Michihira; Taguchi, Ayumi; Takahashi, Hazuki; Takahashi, Masayo; Takamochi, Kazuya; Takeda, Satoru; Takenaka, Yoichi; Tam, Kin Tung; Tanaka, Hiroshi; Tanaka, Rica; Tanaka, Yuji; Tang, Dave; Taniuchi, Ichiro; Tanzer, Andrea; Tarui, Hiroshi; Taylor, Martin S.; Terada, Aika; Terao, Yasuhisa; Testa, Alison C.; Thomas, Mark; Thongjuea, Supat; Tomii, Kentaro; Triglia, Elena Torlai; Toyoda, Hiroo; Tsang, H. Gwen; Tsujikawa, Motokazu; Uhlén, Mathias; Valen, Eivind Dale; van de Wetering, Marc; van Nimwegen, Erik; Velmeshev, Dmitry; Verardo, Roberto; Vitezic, Morana; Vitting-Seerup, Kristoffer; von Feilitzen, Kalle; Voolstra, Christian R.; Vorontsov, Ilya E.; Wahlestedt, Claes; Wasserman, Wyeth W.; Watanabe, Kazuhide; Watanabe, Shoko; Wells, Christine A.; Winteringham, Louise N.; Wolvetang, Ernst; Yabukami, Haruka; Yagi, Ken; Yamada, Takuji; Yamaguchi, Yoko; Yamamoto, Masayuki; Yamamoto, Yasutomo; Yamamoto, Yumiko; Yamanaka, Yasunari; Yano, Kojiro; Yasuzawa, Kayoko; Yatsuka, Yukiko; Yo, Masahiro; Yokokura, Shunji; Yoneda, Misako; Yoshida, Emiko; Yoshida, Yuki; Yoshihara, Masahito; Young, Rachel; Young, Robert S.; Yu, Nancy Y.; Yumoto, Noriko; Zabierowski, Susan E.; Zhang, Peter G.; Zucchelli, Silvia; Zwahlen, Martin; Chatelain, Clément; Carninci, Piero; de Hoon, Michiel J. L.; Wasserman, Wyeth W.; Bréhélin, Laurent; Lecellier, Charles-Henri. (2021) Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network. Nature Communications. vol. 12 (1).
  • Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Olsen, Lene Christin; Chawla, Konika; Aas, Per Arne; Sætrom, Pål. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports. vol. 11:18952.
  • Hildrestrand, Gunn Annette; Rolseth, Veslemøy; Kunath, Nicolas; Suganthan, Rajikala; Jensen, Vidar; Bugaj, Anna Maria; Fernandez Berrocal, Marion Silvana; SIkko, Sunniva Bøe; Vetlesen, Susanne; Kusnierczyk, Anna; Olsen, Ann-Karin Hardie; Gutzkow, Kristine Bjerve; Rowe, Alexander D.; Wang, Wei; Moldestad, Olve; Syrstad, Monica Dahl; Slupphaug, Geir; Eide, Lars; Klungland, Arne; Sætrom, Pål; Luna, Luisa; Ye, Jing; Scheffler, Katja; Bjørås, Magnar. (2021) NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice. Communications Biology. vol. 4.
  • Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira. (2021) Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth. Genomics. vol. 113 (5).
  • Rolinski, Milosz; Montaldo, Nicola Pietro; Aksu, Merdane Ezgi; Martin, Sarah Fordyce; Brambilla, Alessandro; Kunath, Nicolas; Johansen, Jostein; Erlandsen, Sten Even; Liabakk, Nina-Beate; Rian, Kristin; Bjørås, Magnar; Sætrom, Pål; van Loon, Barbara. (2021) Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Research (NAR). vol. 49 (3).
  • Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn; Sætrom, Pål; Wibe, Arne; Schønberg, Svanhild Margrethe Arentz; Pettersen, Caroline Hild. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines.
  • Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Hegre, Siv Anita; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2021) MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity. Experimental Dermatology. vol. 31 (4).
  • Tingö, Lina; Ahlberg, Emelie; Johansson, Lovisa; Pedersen, Sindre Andre; Chawla, Konika; Sætrom, Pål; Cione, Erika; Simpson, Melanie Rae. (2021) Non-coding RNAs in human breast milk: A systematic review. Frontiers in Immunology. vol. 12:725323.
  • Huang, Kai-Wen; Reebye, Vikash; Czysz, Katherine; Ciriello, Simona; Dorman, Stephanie; Reccia, Isabella; Lai, Hong-Shiee; Peng, Ling; Kostomitsopoulos, Nikos; Nicholls, Joanna; Habib, Robert; Tomalia, Donald A.; Sætrom, Pål; Wilkes, Edmund; Cutillas, Pedro; Rossi, John; Habib, Nagy. (2020) Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile. Molecular Therapy - Nucleic Acids. vol. 19.
  • Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira. (2020) Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication. Epigenetics. vol. 15 (10).
  • Mjelle, Robin; Aass, Kristin Roseth; Sjursen, Wenche; Hofsli, Eva; Sætrom, Pål. (2020) sMETASeq: combined profiling of microbiota and host small RNAs. iScience.
  • Sarker, Debashis; Plummer, Ruth; Meyer, Tim; Sodergren, Mikael H; Basu, Bristi; Chee, Cheng Ean; Huang, Kai-Wen; Palmer, Daniel H; Ma, Yuk Ting; Evans, T R Jeff; Spalding, Duncan R C; Pai, Madhava; Sharma, Rohini; Pinato, David J; Spicer, James; Hunter, Sarah; Kwatra, Vineet; Nicholls, Joanna P; Collin, David; Nutbrown, Robert; Glenny, Helen; Fairbairn, Sonia; Reebye, Vikash; Voutila, Jon; Dorman, Stephanie; Andrikakou, Pinelopi; Lloyd, Peter; Felstead, Steve; Vasara, Jenni; Habib, Robert; Wood, Chris; Sætrom, Pål; Huber, Hans E; Blakey, David C.; Rossi, JJ; Habib, Nagy. (2020) MTL-CEBPA, a Small Activating RNA Therapeutic Upregulating C/EBP-α, in Patients with Advanced Liver Cancer: A First-in-Human, Multicenter, Open-Label, Phase I Trial. Clinical Cancer Research. vol. 26 (15).
  • Brian, Ben F; Jolicoeur, Adrienne S; Guerrero, Candace R.; Nunez, Myra G; Sychev, Zoi E; Hegre, Siv Anita; Sætrom, Pål; Habib, Nagy; Drake, Justin M; Schwertfeger, Kathryn L; Freedman, Tanya S.. (2019) Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. eLIFE. vol. 8.
  • Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo Huroz, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis; Nilsen, Hilde. (2019) SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing. Cell reports.
  • Larose, Tricia L; Sætrom, Pål; Martinussen, Marit; Skogseth, Haakon; Sandanger, Torkjel M; Scélo, Ghislaine; McHale, Cliona M.; Jacobsen, Geir Wenberg; Smith, Martyn T.. (2019) In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol. Journal of Public Health Research. vol. 8 (2).
  • Mjelle, Robin; Dima, Simona O; Bacalbasa, Nicolae; Chawla, Konika; Sorop, Andrei; Cucu, Dana; Herlea, Vlad; Sætrom, Pål; Popescu, Irinel. (2019) Comprehensive transcriptomic analyses of tissue, serum, and serum exosomes from hepatocellular carcinoma patients. BMC Cancer. vol. 19 (1).
  • Mjelle, Robin; Sjursen, Wenche; Thommesen, Liv; Sætrom, Pål; Hofsli, Eva. (2019) Small RNA expression from viruses, bacteria and human miRNAs in colon cancer tissue and its association with microsatellite instability and tumor location. BMC Cancer. vol. 19 (1).
  • Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin; Kunath, Nicolas; Otterlei, Marit; Sætrom, Pål; Bjørås, Magnar; Samson, Leona D.; van Loon, Barbara. (2019) Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications. vol. 10 (1).
  • Solvin, Åshild Øksnevad; Chawla, Konika; Olsen, Lene Christin; Danielsen, Kjersti; Jenssen, Marita; Furberg, Anne-Sofie; Saunes, Marit; Hveem, Kristian; Sætrom, Pål; Løset, Mari. (2019) Combined mRNA and miRNA Analysis of Psoriatic Skin. Forum for Nordic Dermato-Venereology. vol. 24 (2).