Eivind Coward
Om
På K.G. Jebsen-senter for genetisk epidemiologi forsker jeg på sammenhenger mellom genetikk, proteomikk, mikrobiota og ulike fenotyper, spesielt beinmassetetthet, beinbrudd og osteoporose. Dette er basert på data fra Helseundersøkelsen i Trøndelag (HUNT) og andre befolkningsbaserte undersøkelser, samt diagnosedata fra sykehus og helseregistre. Jeg er også involvert i forskning på mutasjoner og genuttrykk i kreft, spesielt myelomatose.
Min bakgrunn er fra matematikk og bioinformatikk. Jeg er også involvert i kjernefasiliteten for bioinformatikk og i Elixir, infrastrukturnettverket for bioinformatikk.
Publikasjoner
2022
- Brumpton, Ben Michael; Graham, Sarah; Surakka, Ida; Skogholt, Anne Heidi; Løset, Mari; Fritsche, Lars G.; Wolford, Brooke; Zhou, Wei; Nielsen, Jonas Bille; Holmen, Oddgeir Lingaas; Gabrielsen, Maiken Elvestad; Thomas, Laurent; Bhatta, Laxmi; Rasheed, Humaira; Zhang, He; Kang, Hyun Min; Hornsby, Whitney; Moksnes, Marta Riise; Coward, Eivind; Melbye, Mads; Giskeødegård, Guro F.; Fenstad, Jørn; Krokstad, Steinar; Næss, Marit; Langhammer, Arnulf; Boehnke, Michael; Abecasis, Gonçalo R.; Åsvold, Bjørn Olav; Hveem, Kristian; Willer, Cristen J.. (2022) The HUNT study: A population-based cohort for genetic research. Cell Genomics. volum 2 (10).
- Grahnemo, Louise; Nethander, Maria; Coward, Eivind; Gabrielsen, Maiken Elvestad; Sree, Satya; Billod, Jean-Marc; Engstrand, Lars; Abrahamsson, Sanna; Langhammer, Arnulf; Hveem, Kristian; Ohlsson, Claes. (2022) Cross-sectional associations between the gut microbe Ruminococcus gnavus and features of the metabolic syndrome. The Lancet Diabetes and Endocrinology. volum 10 (7).
- Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco M.; Rustad, Even Holth; Sanders, Mathijs A.; Rye, Morten Beck; Sponaas, Anne-Marit; van der Holt, Bronno; Zweegman, Sonja; Hovig, Eivind; Meza, Leonardo Zepeda; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders. (2022) Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence. Leukemia. volum 36 (7).
- Nethander, Maria; Coward, Eivind; Reimann, Ene; Grahnemo, Louise; Gabrielsen, Maiken Elvestad; Wibom, Carl; Nelis, Mari; Milani, Lili; Esko, Tõnu; Metspalu, Andres; Mägi, Reedik; Funck-Brentano, Thomas; Hoff, Mari; Langhammer, Arnulf; Pettersson-Kymmer, Ulrika; Hveem, Kristian; Ohlsson, Claes. (2022) Assessment of the genetic and clinical determinants of hip fracture risk: Genome-wide association and Mendelian randomization study. Cell Reports Medicine. volum 3 (10).
2019
- Rustad, Even Holth; Misund, Kristine; Bernard, Elsa; Coward, Eivind; Yellapantula, Venkata D; Hultcrantz, Malin; Ho, Caleb; Kazandjian, Dickran; Korde, Neha; Mailankody, Sham; Keats, Jonathan J; Akhlaghi, Theresia; Viny, Aaron D; Mayman, David J; Carroll, Kaitlin; Patel, Minal; Famulare, Christopher A; Hofste op Bruinink, Davine; Hutt, Kasey; Jacobsen, Austin; Huang, Ying; Miller, Jeffrey E; Maura, Francesco; Papaemmanuil, Elli; Waage, Anders; Arcila, Maria E; Landgren, Ola. (2019) Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma. American Journal of Hematology. volum 94 (12).
2018
- Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders. (2018) Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. Blood.
2017
- Rustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese; Børset, Magne; Beisvag, Vidar; Myklebost, Ola; Meza, Leonardo Zepeda; Hong, Yan Dai; Sundan, Anders; Waage, Anders. (2017) Monitoring multiple myeloma by quantification of recurrent mutations in serum. Haematologica. volum 102 (7).
2016
- Våtsveen, Thea Kristin; Børset, Magne; Dikic, Aida; Tian, Erming; Micci, Francesca; Lid, Ana Barragan; Meza-Zepeda, Leonardo A.; Coward, Eivind; Waage, Anders; Sundan, Anders; Kuehl, W. Michael; Holien, Toril. (2016) VOLIN and KJON—Two novel hyperdiploid myeloma cell lines. Genes, Chromosomes and Cancer. volum 55 (11).
2015
- Bakke, Ingrid; Coward, Eivind; Andersen, Tom; Vadstein, Olav. (2015) Selection in the host structures the microbiota associated with developing cod larvae (Gadus morhua). Environmental Microbiology. volum 17 (10).
- Rustad, Even Holth; Dai, Hong Yan; Coward, Eivind; Misund, Kristine; Sundan, Anders; Waage, Anders. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA. Blood. volum 126 (23).
- Rustad, Even Holth; Dai, Hong Yan; Hov, Håkon; Coward, Eivind; Beisvag, Vidar; Myklebost, Ola; Hovig, Johannes Eivind; Nakken, Sigve; Vodak, Daniel; Meza, Leonardo Zepeda; Sandvik, Arne Kristian; Wader, Karin Fahl; Misund, Kristine; Sundan, Anders; Aarset, Harald; Waage, Anders. (2015) BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. Blood Cancer Journal. volum 5:e299 (3).
Tidsskriftspublikasjoner
- Brumpton, Ben Michael; Graham, Sarah; Surakka, Ida; Skogholt, Anne Heidi; Løset, Mari; Fritsche, Lars G.; Wolford, Brooke; Zhou, Wei; Nielsen, Jonas Bille; Holmen, Oddgeir Lingaas; Gabrielsen, Maiken Elvestad; Thomas, Laurent; Bhatta, Laxmi; Rasheed, Humaira; Zhang, He; Kang, Hyun Min; Hornsby, Whitney; Moksnes, Marta Riise; Coward, Eivind; Melbye, Mads; Giskeødegård, Guro F.; Fenstad, Jørn; Krokstad, Steinar; Næss, Marit; Langhammer, Arnulf; Boehnke, Michael; Abecasis, Gonçalo R.; Åsvold, Bjørn Olav; Hveem, Kristian; Willer, Cristen J.. (2022) The HUNT study: A population-based cohort for genetic research. Cell Genomics. volum 2 (10).
- Grahnemo, Louise; Nethander, Maria; Coward, Eivind; Gabrielsen, Maiken Elvestad; Sree, Satya; Billod, Jean-Marc; Engstrand, Lars; Abrahamsson, Sanna; Langhammer, Arnulf; Hveem, Kristian; Ohlsson, Claes. (2022) Cross-sectional associations between the gut microbe Ruminococcus gnavus and features of the metabolic syndrome. The Lancet Diabetes and Endocrinology. volum 10 (7).
- Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco M.; Rustad, Even Holth; Sanders, Mathijs A.; Rye, Morten Beck; Sponaas, Anne-Marit; van der Holt, Bronno; Zweegman, Sonja; Hovig, Eivind; Meza, Leonardo Zepeda; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders. (2022) Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence. Leukemia. volum 36 (7).
- Nethander, Maria; Coward, Eivind; Reimann, Ene; Grahnemo, Louise; Gabrielsen, Maiken Elvestad; Wibom, Carl; Nelis, Mari; Milani, Lili; Esko, Tõnu; Metspalu, Andres; Mägi, Reedik; Funck-Brentano, Thomas; Hoff, Mari; Langhammer, Arnulf; Pettersson-Kymmer, Ulrika; Hveem, Kristian; Ohlsson, Claes. (2022) Assessment of the genetic and clinical determinants of hip fracture risk: Genome-wide association and Mendelian randomization study. Cell Reports Medicine. volum 3 (10).
- Rustad, Even Holth; Misund, Kristine; Bernard, Elsa; Coward, Eivind; Yellapantula, Venkata D; Hultcrantz, Malin; Ho, Caleb; Kazandjian, Dickran; Korde, Neha; Mailankody, Sham; Keats, Jonathan J; Akhlaghi, Theresia; Viny, Aaron D; Mayman, David J; Carroll, Kaitlin; Patel, Minal; Famulare, Christopher A; Hofste op Bruinink, Davine; Hutt, Kasey; Jacobsen, Austin; Huang, Ying; Miller, Jeffrey E; Maura, Francesco; Papaemmanuil, Elli; Waage, Anders; Arcila, Maria E; Landgren, Ola. (2019) Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma. American Journal of Hematology. volum 94 (12).
- Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders. (2018) Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. Blood.
- Rustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese; Børset, Magne; Beisvag, Vidar; Myklebost, Ola; Meza, Leonardo Zepeda; Hong, Yan Dai; Sundan, Anders; Waage, Anders. (2017) Monitoring multiple myeloma by quantification of recurrent mutations in serum. Haematologica. volum 102 (7).
- Våtsveen, Thea Kristin; Børset, Magne; Dikic, Aida; Tian, Erming; Micci, Francesca; Lid, Ana Barragan; Meza-Zepeda, Leonardo A.; Coward, Eivind; Waage, Anders; Sundan, Anders; Kuehl, W. Michael; Holien, Toril. (2016) VOLIN and KJON—Two novel hyperdiploid myeloma cell lines. Genes, Chromosomes and Cancer. volum 55 (11).
- Bakke, Ingrid; Coward, Eivind; Andersen, Tom; Vadstein, Olav. (2015) Selection in the host structures the microbiota associated with developing cod larvae (Gadus morhua). Environmental Microbiology. volum 17 (10).
- Rustad, Even Holth; Dai, Hong Yan; Coward, Eivind; Misund, Kristine; Sundan, Anders; Waage, Anders. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA. Blood. volum 126 (23).
- Rustad, Even Holth; Dai, Hong Yan; Hov, Håkon; Coward, Eivind; Beisvag, Vidar; Myklebost, Ola; Hovig, Johannes Eivind; Nakken, Sigve; Vodak, Daniel; Meza, Leonardo Zepeda; Sandvik, Arne Kristian; Wader, Karin Fahl; Misund, Kristine; Sundan, Anders; Aarset, Harald; Waage, Anders. (2015) BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. Blood Cancer Journal. volum 5:e299 (3).