Eivind Coward
Om
På K.G. Jebsen-senter for genetisk epidemiologi forsker jeg på sammenhenger mellom genetikk, proteomikk, mikrobiota og ulike fenotyper, spesielt beinmassetetthet, beinbrudd og osteoporose. Dette er basert på data fra Helseundersøkelsen i Trøndelag (HUNT) og andre befolkningsbaserte undersøkelser, samt diagnosedata fra sykehus og helseregistre. Jeg er også involvert i forskning på mutasjoner og genuttrykk i kreft, spesielt myelomatose.
Min bakgrunn er fra matematikk og bioinformatikk. Jeg er også involvert i kjernefasiliteten for bioinformatikk og i Elixir, infrastrukturnettverket for bioinformatikk.
Publikasjoner
2026
-
Dekkers, Koen F.;
Pertiwi, Kamalita;
Baldanzi, Gabriel;
Lundmark, Per;
Hammar, Ulf;
Moksnes, Marta Riise;
Coward, Eivind;
Nethander, Maria;
Salih, Ghassan Ali;
Miari, Mariam.
(2026)
Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation.
Nature Genetics
Vitenskapelig artikkel
-
Moksnes, Marta Riise;
Coward, Eivind;
Nethander, Maria;
Dekkers, Koen;
Grahnemo, Louise;
Törnqvist, Anna E.;
Li, Lei;
Lundmark, Per;
Pertiwi, Kamalita;
Baldanzi, Gabriel.
(2026)
The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota composition.
Nature Genetics
Vitenskapelig artikkel
2024
-
Austin, Thomas R.;
Nethander, Maria;
Fink, Howard A.;
Törnqvist, Anna E.;
Jalal, Diana I.;
Buzkova, Petra;
Barzilay, Joshua I.;
Carbone, Laura;
Gabrielsen, Maiken Elvestad;
Grahnemo, Louise.
(2024)
A plasma protein-based risk score to predict hip fractures.
Nature Aging
Kommentar
-
Austin, Thomas R.;
Fink, Howard A.;
Jalal, Diana I.;
Törnqvist, Anna E.;
Buzkova, Petra;
Barzilay, Joshua I.;
Lu, Tianyuan;
Carbone, Laura;
Gabrielsen, Maiken Elvestad;
Grahnemo, Louise.
(2024)
Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures.
Journal of Bone and Mineral Research
Vitenskapelig artikkel
-
Quester, Johan;
Nethander, Maria;
Coward, Eivind;
Reimann, Ene;
Mägi, Reedik;
Hudjashov, Georgi;
Nelis, Mari;
Esko, Tõnu;
Milani, Lili;
Metspalu, Andres.
(2024)
High SHBG and Low Bioavailable Testosterone are Strongly Causally Associated with Increased Forearm Fracture Risk in Women: An MR Study Leveraging Novel Female-Specific Data.
Calcified Tissue International
Vitenskapelig artikkel
-
Austin, Thomas R.;
Nethander, Maria;
Fink, Howard A.;
Törnqvist, Anna E.;
Jalal, Diana I.;
Buzkova, Petra;
Barzilay, Joshua I.;
Carbone, Laura;
Gabrielsen, Maiken Elvestad;
Grahnemo, Louise.
(2024)
Correction to: A plasma protein-based risk score to predict hip fractures (Nature Aging, (2024), 4, 8, (1064-1075), 10.1038/s43587-024-00639-7).
Nature Aging
Korrigendum
2023
-
Lawenius, Lina;
Cowardin, Carrie;
Grahnemo, Louise;
Scheffler, Julia M.;
Horkeby, Karin;
Engdahl, Cecilia;
Wu, Jianyao;
Vandenput, Liesbeth;
Koskela, Antti;
Tukkanen, Juha.
(2023)
Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone mass.
Gut microbes
Vitenskapelig artikkel
-
Nethander, Maria;
Movérare-Skrtic, Sofia;
Kämpe, Anders;
Coward, Eivind;
Reimann, Ene;
Grahnemo, Louise;
Borbély, Éva;
Helyes, Zsuzsanna;
Funck-Brentano, Thomas;
Cohen-Solal, Martine.
(2023)
An atlas of genetic determinants of forearm fracture.
Nature Genetics
Vitenskapelig artikkel
-
Grahnemo, Louise;
Nethander, Maria;
Coward, Eivind;
Gabrielsen, Maiken Elvestad;
Sree, Satya;
Billod, Jean-Marc;
Sjögren, Klara;
Engstrand, Lars;
Dekkers, Koen F.;
Fall, Tove.
(2023)
Identification of three bacterial species associated with increased appendicular lean mass: the HUNT study.
Nature Communications
Vitenskapelig artikkel
2022
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G.;
Wolford, Brooke;
Zhou, Wei;
Nielsen, Jonas Bille;
Holmen, Oddgeir Lingaas.
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics
Vitenskapelig artikkel
-
Nethander, Maria;
Coward, Eivind;
Reimann, Ene;
Grahnemo, Louise;
Gabrielsen, Maiken Elvestad;
Wibom, Carl;
Nelis, Mari;
Milani, Lili;
Esko, Tõnu;
Metspalu, Andres.
(2022)
Assessment of the genetic and clinical determinants of hip fracture risk: Genome-wide association and Mendelian randomization study.
Cell Reports Medicine
Vitenskapelig artikkel
-
Misund, Kristine;
Bruinink, Davine Hofste op;
Coward, Eivind;
Hoogenboezem, Remco M.;
Rustad, Even Holth;
Sanders, Mathijs A.;
Rye, Morten Beck;
Sponaas, Anne-Marit;
Holt, Bronno van der;
Zweegman, Sonja.
(2022)
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence.
Leukemia
Vitenskapelig artikkel
-
Grahnemo, Louise;
Nethander, Maria;
Coward, Eivind;
Gabrielsen, Maiken Elvestad;
Sree, Satya;
Billod, Jean-Marc;
Engstrand, Lars;
Abrahamsson, Sanna;
Langhammer, Arnulf;
Hveem, Kristian.
(2022)
Cross-sectional associations between the gut microbe Ruminococcus gnavus and features of the metabolic syndrome.
The Lancet Diabetes and Endocrinology
Kommentar
-
Giliberto, Mariaserena;
Miranda Santana, Leonardo;
Holien, Toril;
Misund, Kristine;
Nakken, Sigve;
Vodak, Daniel;
Hovig, Eivind;
Meza, Leonardo Zepeda;
Coward, Eivind;
Waage, Anders.
(2022)
Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines.
Frontiers in Oncology
Vitenskapelig artikkel
2019
-
Rustad, Even Holth;
Misund, Kristine;
Bernard, Elsa;
Coward, Eivind;
Yellapantula, Venkata D;
Hultcrantz, Malin;
Ho, Caleb;
Kazandjian, Dickran;
Korde, Neha;
Mailankody, Sham.
(2019)
Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma.
American Journal of Hematology
Vitenskapelig artikkel
2018
-
Misund, Kristine;
Bruinink, Davine Hofste op;
Coward, Eivind;
Hoogenboezem, Remco;
Rustad, Even Holth;
Hovig, Eivind;
Sundan, Anders;
Myklebost, Ola;
Sonneveld, Pieter;
Waage, Anders.
(2018)
Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse.
Blood
Konferanseabstract
2017
-
Rustad, Even Holth;
Coward, Eivind;
Skytøen, Emilie R;
Misund, Kristine;
Holien, Toril;
Standal, Therese;
Børset, Magne;
Beisvag, Vidar;
Myklebost, Ola;
Meza, Leonardo Zepeda.
(2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum.
Haematologica
Vitenskapelig artikkel
2016
-
Våtsveen, Thea Kristin;
Børset, Magne;
Dikic, Aida;
Tian, Erming;
Micci, Francesca;
Lid, Ana Barragan;
Meza-Zepeda, Leonardo A.;
Coward, Eivind;
Waage, Anders;
Sundan, Anders.
(2016)
VOLIN and KJON—Two novel hyperdiploid myeloma cell lines.
Genes, Chromosomes and Cancer
Vitenskapelig artikkel
2015
-
Rustad, Even Holth;
Dai, Hong Yan;
Hov, Håkon;
Coward, Eivind;
Beisvag, Vidar;
Myklebost, Ola;
Hovig, Johannes Eivind;
Nakken, Sigve;
Vodak, Daniel;
Meza, Leonardo Zepeda.
(2015)
BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis.
Blood Cancer Journal
Vitenskapelig artikkel
-
Bakke, Ingrid;
Coward, Eivind;
Andersen, Tom;
Vadstein, Olav.
(2015)
Selection in the host structures the microbiota
associated with developing cod larvae (Gadus morhua).
Environmental Microbiology
Vitenskapelig artikkel
-
Rustad, Even Holth;
Dai, Hong Yan;
Coward, Eivind;
Misund, Kristine;
Sundan, Anders;
Waage, Anders.
(2015)
Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA.
Blood
Konferanseabstract
Tidsskriftspublikasjoner
-
Dekkers, Koen F.;
Pertiwi, Kamalita;
Baldanzi, Gabriel;
Lundmark, Per;
Hammar, Ulf;
Moksnes, Marta Riise;
Coward, Eivind;
Nethander, Maria;
Salih, Ghassan Ali;
Miari, Mariam.
(2026)
Genome-wide association analyses highlight the role of the intestinal molecular environment in human gut microbiota variation.
Nature Genetics
Vitenskapelig artikkel
-
Moksnes, Marta Riise;
Coward, Eivind;
Nethander, Maria;
Dekkers, Koen;
Grahnemo, Louise;
Törnqvist, Anna E.;
Li, Lei;
Lundmark, Per;
Pertiwi, Kamalita;
Baldanzi, Gabriel.
(2026)
The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota composition.
Nature Genetics
Vitenskapelig artikkel
-
Rustad, Even Holth;
Coward, Eivind;
Skytøen, Emilie R;
Misund, Kristine;
Holien, Toril;
Standal, Therese;
Børset, Magne;
Beisvag, Vidar;
Myklebost, Ola;
Meza, Leonardo Zepeda.
(2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum.
Haematologica
Vitenskapelig artikkel
-
Austin, Thomas R.;
Nethander, Maria;
Fink, Howard A.;
Törnqvist, Anna E.;
Jalal, Diana I.;
Buzkova, Petra;
Barzilay, Joshua I.;
Carbone, Laura;
Gabrielsen, Maiken Elvestad;
Grahnemo, Louise.
(2024)
A plasma protein-based risk score to predict hip fractures.
Nature Aging
Kommentar
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G.;
Wolford, Brooke;
Zhou, Wei;
Nielsen, Jonas Bille;
Holmen, Oddgeir Lingaas.
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics
Vitenskapelig artikkel
-
Lawenius, Lina;
Cowardin, Carrie;
Grahnemo, Louise;
Scheffler, Julia M.;
Horkeby, Karin;
Engdahl, Cecilia;
Wu, Jianyao;
Vandenput, Liesbeth;
Koskela, Antti;
Tukkanen, Juha.
(2023)
Transplantation of gut microbiota from old mice into young healthy mice reduces lean mass but not bone mass.
Gut microbes
Vitenskapelig artikkel
-
Rustad, Even Holth;
Misund, Kristine;
Bernard, Elsa;
Coward, Eivind;
Yellapantula, Venkata D;
Hultcrantz, Malin;
Ho, Caleb;
Kazandjian, Dickran;
Korde, Neha;
Mailankody, Sham.
(2019)
Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma.
American Journal of Hematology
Vitenskapelig artikkel
-
Nethander, Maria;
Coward, Eivind;
Reimann, Ene;
Grahnemo, Louise;
Gabrielsen, Maiken Elvestad;
Wibom, Carl;
Nelis, Mari;
Milani, Lili;
Esko, Tõnu;
Metspalu, Andres.
(2022)
Assessment of the genetic and clinical determinants of hip fracture risk: Genome-wide association and Mendelian randomization study.
Cell Reports Medicine
Vitenskapelig artikkel
-
Misund, Kristine;
Bruinink, Davine Hofste op;
Coward, Eivind;
Hoogenboezem, Remco M.;
Rustad, Even Holth;
Sanders, Mathijs A.;
Rye, Morten Beck;
Sponaas, Anne-Marit;
Holt, Bronno van der;
Zweegman, Sonja.
(2022)
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence.
Leukemia
Vitenskapelig artikkel
-
Rustad, Even Holth;
Dai, Hong Yan;
Hov, Håkon;
Coward, Eivind;
Beisvag, Vidar;
Myklebost, Ola;
Hovig, Johannes Eivind;
Nakken, Sigve;
Vodak, Daniel;
Meza, Leonardo Zepeda.
(2015)
BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis.
Blood Cancer Journal
Vitenskapelig artikkel
-
Nethander, Maria;
Movérare-Skrtic, Sofia;
Kämpe, Anders;
Coward, Eivind;
Reimann, Ene;
Grahnemo, Louise;
Borbély, Éva;
Helyes, Zsuzsanna;
Funck-Brentano, Thomas;
Cohen-Solal, Martine.
(2023)
An atlas of genetic determinants of forearm fracture.
Nature Genetics
Vitenskapelig artikkel
-
Austin, Thomas R.;
Fink, Howard A.;
Jalal, Diana I.;
Törnqvist, Anna E.;
Buzkova, Petra;
Barzilay, Joshua I.;
Lu, Tianyuan;
Carbone, Laura;
Gabrielsen, Maiken Elvestad;
Grahnemo, Louise.
(2024)
Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures.
Journal of Bone and Mineral Research
Vitenskapelig artikkel
-
Bakke, Ingrid;
Coward, Eivind;
Andersen, Tom;
Vadstein, Olav.
(2015)
Selection in the host structures the microbiota
associated with developing cod larvae (Gadus morhua).
Environmental Microbiology
Vitenskapelig artikkel
-
Grahnemo, Louise;
Nethander, Maria;
Coward, Eivind;
Gabrielsen, Maiken Elvestad;
Sree, Satya;
Billod, Jean-Marc;
Engstrand, Lars;
Abrahamsson, Sanna;
Langhammer, Arnulf;
Hveem, Kristian.
(2022)
Cross-sectional associations between the gut microbe Ruminococcus gnavus and features of the metabolic syndrome.
The Lancet Diabetes and Endocrinology
Kommentar
-
Giliberto, Mariaserena;
Miranda Santana, Leonardo;
Holien, Toril;
Misund, Kristine;
Nakken, Sigve;
Vodak, Daniel;
Hovig, Eivind;
Meza, Leonardo Zepeda;
Coward, Eivind;
Waage, Anders.
(2022)
Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines.
Frontiers in Oncology
Vitenskapelig artikkel
-
Rustad, Even Holth;
Dai, Hong Yan;
Coward, Eivind;
Misund, Kristine;
Sundan, Anders;
Waage, Anders.
(2015)
Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA.
Blood
Konferanseabstract
-
Quester, Johan;
Nethander, Maria;
Coward, Eivind;
Reimann, Ene;
Mägi, Reedik;
Hudjashov, Georgi;
Nelis, Mari;
Esko, Tõnu;
Milani, Lili;
Metspalu, Andres.
(2024)
High SHBG and Low Bioavailable Testosterone are Strongly Causally Associated with Increased Forearm Fracture Risk in Women: An MR Study Leveraging Novel Female-Specific Data.
Calcified Tissue International
Vitenskapelig artikkel
-
Grahnemo, Louise;
Nethander, Maria;
Coward, Eivind;
Gabrielsen, Maiken Elvestad;
Sree, Satya;
Billod, Jean-Marc;
Sjögren, Klara;
Engstrand, Lars;
Dekkers, Koen F.;
Fall, Tove.
(2023)
Identification of three bacterial species associated with increased appendicular lean mass: the HUNT study.
Nature Communications
Vitenskapelig artikkel
-
Austin, Thomas R.;
Nethander, Maria;
Fink, Howard A.;
Törnqvist, Anna E.;
Jalal, Diana I.;
Buzkova, Petra;
Barzilay, Joshua I.;
Carbone, Laura;
Gabrielsen, Maiken Elvestad;
Grahnemo, Louise.
(2024)
Correction to: A plasma protein-based risk score to predict hip fractures (Nature Aging, (2024), 4, 8, (1064-1075), 10.1038/s43587-024-00639-7).
Nature Aging
Korrigendum
-
Misund, Kristine;
Bruinink, Davine Hofste op;
Coward, Eivind;
Hoogenboezem, Remco;
Rustad, Even Holth;
Hovig, Eivind;
Sundan, Anders;
Myklebost, Ola;
Sonneveld, Pieter;
Waage, Anders.
(2018)
Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse.
Blood
Konferanseabstract
-
Våtsveen, Thea Kristin;
Børset, Magne;
Dikic, Aida;
Tian, Erming;
Micci, Francesca;
Lid, Ana Barragan;
Meza-Zepeda, Leonardo A.;
Coward, Eivind;
Waage, Anders;
Sundan, Anders.
(2016)
VOLIN and KJON—Two novel hyperdiploid myeloma cell lines.
Genes, Chromosomes and Cancer
Vitenskapelig artikkel
Undervisning
Emner
Formidling
2025
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KonferanseposterGrahnemo, Louise; Nethander, Maria; Sjögren, Klara; Coward, Eivind; Thingstad, Anne Pernille Mæhle; Skjellegrind, Håvard Kjesbu; Selbæk, Geir; Hveem, Kristian; Michaëlsson, Karl; Ohlsson, Claes. (2025) Gut microbiota composition is reproducibly associated with muscle function in older adults. The human microbiomr
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KonferanseposterMoksnes, Marta Riise; Coward, Eivind; Nethander, Maria; Dekkers, Koen; Grahnemo, Louise; Törnqvist, Anna E; Li, Lei; Lundmark, Per; Pertiwi, Kamalita; Baldanzi, Gabriel. (2025) Novel host genetic factors reproducibly associated with human gut microbiota composition – The HUNT study. The human microbiome
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Konferanseforedrag
2024
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KonferanseposterCoward, Eivind; Austin, Thomas R.; Nethander, Maria; Fink, Howard A.; Törnqvist, Anna E.; Hveem, Kristian; Ohlsson, Claes. (2024) A plasma protein-based risk score to predict hip fractures. Nordic Conference of Future Health
2021
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KonferanseforedragBakke, Ingrid; Coward, Eivind; Lorentsen, Eirik Degre; Vadstein, Olav. (2021) Temporal and interindividual variation in hindgut microbiomes among four codfish species in the subfamily Gadinae. The third international fish - microbiota workshop
2018
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KonferanseforedragMisund, Kristine; Bruinink, Davine Hofste op; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders. (2018) Clonal Evolution of Multiple Myeloma After Treatment with Novel Agents. 2nd. International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer
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KonferanseposterMisund, Kristine; Bruinink, Davine Hofste op; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders. (2018) Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. American Society of Hematology (ASH) 2018
2017
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KonferanseforedragMisund, Kristine; Bruinink, Davine Hofste op; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind; Sundan, Anders; Myklebost, Ola; Sonneveld, Pieter; Waage, Anders. (2017) Detection of mutations in Multiple Myeloma during different stages of disease. NMSG plenary meeting
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KonferanseposterCoward, Eivind; Misund, Kristine; Bruinink, Davine Hofste op; Hoogenboezem, Remco; Rustad, Even Holth; Myklebost, Ola; Sundan, Anders; Sonneveld, Pieter; Waage, Anders. (2017) Exome sequencing of multiple myeloma at sequential time points. Trondheim - Oslo Genome Dynamics Workshop
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Konferanseposter
2016
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KonferanseposterRustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese; Dai, Hong Yan; Sundan, Anders; Waage, Anders. (2016) Circulating Tumor DNA in Multiple Myeloma. European Hematology Association 21th Congress
2015
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KonferanseposterRustad, Even Holth; Dai, Hong Yan; Coward, Eivind; Misund, Kristine; Sundan, Anders; Waage, Anders. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA. 57th ASH Annual Meeting and Exposition
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KonferanseforedragRustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Dai, Hong Yan; Sundan, Anders; Waage, Anders. (2015) Exome sequencing of tumor samples as starting point for monitoring mutations in circulating DNA of patients with multiple myeloma. Norwegian Cancer Genomics Consortium (NCGC) Symposium
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KonferanseforedragCoward, Eivind; Misund, Kristine; Rustad, Even Holth; Sundan, Anders; Waage, Anders. (2015) Mutations in multiple myeloma at sequential time points. NCGC Symposium 2015
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KonferanseforedragRustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Dai, Hong Yan; Sundan, Anders; Waage, Anders. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients by Digital PCR of Circulating DNA. Nordic Myeloma Study Group (NMSG) Annual Meeting
2014
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ForedragMisund, Kristine; Coward, Eivind; Waage, Anders. (2014) Norwegian Cancer Genomics Consortium - Multiple Myeloma projects. Høstmøte for Norsk selskap for Hematologi
2013
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KonferanseforedragBakke, Ingrid; Skjermo, Jorunn; Attramadal, Kari; Coward, Eivind; Kjørsvik, Elin; Vo, Tu Anh; Olsen, Yngvar; Vadstein, Olav. (2013) Bacterial community assembly in developing cod larvae (Gadus morhua). Conference Larvi 2013
2002
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KonferanseforedragMalde, Ketil; Coward, Eivind; Jonasen, Inge. (2002) A Fast Algorithm for EST Clustering using Suffix Trees. Algo 2002 - Workshop on Algorithms in BioInformatics (WABI)