Gaston Courtade

Om

I am an Associate Professor in Biopolymer Science in the Research Division of Biopolymer and Biomaterials at the Department of Biotechnology and Food Science. My main research interest is the study of the structures and functions of enzymes. In particular, protein dynamics and interactions between proteins and carbohydrates.

More information about the Courtade Lab

Publikasjoner

2023

Fages-Lartaud, Maxime; Mueller, Yasmin; Elie, Florence; Courtade, Gaston; Hohmann-Marriott, Martin Frank. (2023) Standard Intein Gene Expression Ramps (SIGER) for Protein-Independent Expression Control. ACS Synthetic Biology
Vitenskapelig artikkel
Christensen, Idd Andrea; Eijsink, Vincent; Stepnov, Anton; Courtade, Gaston; Aachmann, Finn Lillelund. (2023) Following the Fate of Lytic Polysaccharide Monooxygenases under Oxidative Conditions by NMR Spectroscopy. Biochemistry
Vitenskapelig artikkel
Forsberg, Zarah; Stepnov, Anton; Tesei, Giulio; Wang, Yong; Buchinger, Edith; Kristiansen, Sandra. (2023) The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase. Journal of Biological Chemistry
Vitenskapelig artikkel

2022

Forsberg, Zarah; Courtade, Gaston. (2022) On the impact of carbohydrate-binding modules (CBMs) in lytic polysaccharide monooxygenases (LPMOs). Essays in Biochemistry
Vitenskapelig oversiktsartikkel/review
Hellesnes, Kristina Naasen; Vijayaraj, Shunmathi; Fojan, Peter; Petersen, Evamaria; Courtade, Gaston. (2022) Biochemical Characterization and NMR Study of a PET-Hydrolyzing Cutinase from Fusarium solani pisi. Biochemistry
Vitenskapelig artikkel

2021

Stepnov, Anton; Christensen, Idd Andrea; Forsberg, Zarah; Aachmann, Finn Lillelund; Courtade, Gaston; Eijsink, Vincent. (2021) The impact of reductants on the catalytic efficiency of a lytic polysaccharide monooxygenase and the special role of dehydroascorbic acid. FEBS Letters
Vitenskapelig artikkel
Madland, Eva; Forsberg, Zarah; Wang, Yong; Lindorff-Larsen, Kresten; Niebisch, Axel; Modregger, Jan. (2021) Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus. Journal of Biological Chemistry
Vitenskapelig artikkel

2020

Courtade, Gaston; Ciano, Luisa; Paradisi, Alessandro; Lindley, Peter J.; Forsberg, Zarah; Sørlie, Morten. (2020) Mechanistic basis of substrate–O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study. Proceedings of the National Academy of Sciences of the United States of America
Vitenskapelig artikkel
Guerrero-Garzón, Jaime Felipe; Madland, Eva; Zehl, Martin; Singh, Madhurendra; Rezaei, Shiva; Aachmann, Finn Lillelund. (2020) Class IV lasso peptides synergistically induce proliferation of cancer cells and sensitize them to doxorubicin. iScience
Vitenskapelig artikkel
Christensen, Idd Andrea; Eijsink, Vincent; Aachmann, Finn Lillelund; Courtade, Gaston. (2020) 1H, 13C, 15N resonance assignment of the apo form of the small, chitin-active lytic polysaccharide monooxygenase JdLPMO10Afrom Jonesia denitrificans. Biomolecular NMR Assignments
Vitenskapelig artikkel

2019

Courtade, Gaston; Aachmann, Finn Lillelund. (2019) Chitin-Active Lytic Polysaccharide Monooxygenases. Springer
Faglig kapittel
Forsberg, Zarah; Sørlie, Morten; Petrovic, Dejan; Courtade, Gaston; Aachmann, Finn Lillelund; Vaaje-Kolstad, Gustav. (2019) Polysaccharide degradation by lytic polysaccharide monooxygenases. Current Opinion in Structural Biology
Vitenskapelig oversiktsartikkel/review

2018

Courtade, Gaston; Forsberg, Zarah; Heggset, Ellinor Bævre; Eijsink, Vincent; Aachmann, Finn Lillelund. (2018) The carbohydrate-binding module and linker of a modular lytic polysaccharide monooxygenase promote localized cellulose oxidation. Journal of Biological Chemistry
Vitenskapelig artikkel
Courtade, Gaston; Brautaset, Trygve; Aachmann, Finn Lillelund. (2018) An NMR investigation of lytic polysaccharide monooxygenases . Doktoravhandlinger ved NTNU (337)
Doktorgradsavhandling
Kitaoku, Yoshihito; Courtade, Gaston; Petrovic, Dejan; Fukamizo, Tamo; Eijsink, Vincent; Aachmann, Finn Lillelund. (2018) Resonance assignments for the apo-form of the cellulose-active lytic polysaccharide monooxygenase TaLPMO9A. Biomolecular NMR Assignments
Vitenskapelig artikkel
Petrovic, Dejan; Bissaro, Bastien; Chylenski, Piotr; Skaugen, Morten; Sørlie, Morten; Jensen, Marianne Slang. (2018) Methylation of the N-terminal histidine protects a lytic polysaccharide monooxygenase from auto-oxidative inactivation. Protein Science
Vitenskapelig artikkel

2017

Courtade, Gaston; Le, Simone Balzer; Sætrom, Gerd Inger; Brautaset, Trygve; Aachmann, Finn Lillelund. (2017) A novel expression system for lytic polysaccharide monooxygenases. Carbohydrate Research
Vitenskapelig artikkel
Courtade, Gaston; Forsberg, Zarah; Vaaje-Kolstad, Gustav; Eijsink, Vincentius Gerardus Henricus; Aachmann, Finn Lillelund. (2017) Chemical shift assignments for the apo-form of the catalytic domain, the linker region, and the carbohydrate-binding domain of the cellulose-active lytic polysaccharide monooxygenase ScLPMO10C. Biomolecular NMR Assignments
Vitenskapelig artikkel
Crasson, Oscar; Courtade, Gaston; Leonard, Raphael R; Aachmann, Finn Lillelund; Legrand, Francois; Parente, Raffaella. (2017) Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who’s Leading HCHT’s Biological Function. Scientific Reports
Vitenskapelig artikkel

2016

Courtade, Gaston; Wimmer, Reinhard; Dimarogona, Maria; Sandgren, Mats; Eijsink, Vincent; Aachmann, Finn Lillelund. (2016) Backbone and side-chain 1H, 13C, and 15N chemical shift assignments for the apo-form of the lytic polysaccharide monooxygenase NcLPMO9C. Biomolecular NMR Assignments
Vitenskapelig artikkel
Courtade, Gaston; Wimmer, Reinhard; Kjendseth, Åsmund Røhr; Preims, Marita; Felice, Alfons K.G.; Dimarogona, Maria. (2016) Interactions of a fungal lytic polysaccharide monooxygenase with β-glucan substrates and cellobiose dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America
Vitenskapelig artikkel

2015

Courtade, Gaston; Balzer, Simone; Forsberg, Zarah; Vaaje-Kolstad, Gustav; Eijsink, Vincent; Aachmann, Finn Lillelund. (2015) 1H, 13C, 15N resonance assignment of the chitin-active lytic polysaccharide monooxygenase BlLPMO10A from Bacillus licheniformis. Biomolecular NMR Assignments
Vitenskapelig artikkel

2014

Courtade, Gaston; Christensen, Bjørn E.; Ulset, Ann-Sissel Teialeret. (2014) Video demonstration of Biopolymers lab exercises.
Digitale læremidler
Courtade, Gaston; Skjåk-Bræk, Gudmund; Aachmann, Finn Lillelund. (2014) Structural Investigation of a Lytic Polysaccharide Monooxygenase by NMR Spectroscopy . NTNU
Mastergradsoppgave

2013

Gałęcki, Krystian; Courtade, Gaston; McFall, Aisling; Teixeira, Renata Prieschl; Grgic, Maja; Esteve-Sistere, Marta. (2013) Experimental and theoretical investigation of drotaverine binding to bovine serum albumin. Biotechnology and Food Science
Vitenskapelig artikkel

Tidsskriftspublikasjoner

Fages-Lartaud, Maxime; Mueller, Yasmin; Elie, Florence; Courtade, Gaston; Hohmann-Marriott, Martin Frank. (2023) Standard Intein Gene Expression Ramps (SIGER) for Protein-Independent Expression Control. ACS Synthetic Biology
Vitenskapelig artikkel
Christensen, Idd Andrea; Eijsink, Vincent; Stepnov, Anton; Courtade, Gaston; Aachmann, Finn Lillelund. (2023) Following the Fate of Lytic Polysaccharide Monooxygenases under Oxidative Conditions by NMR Spectroscopy. Biochemistry
Vitenskapelig artikkel
Forsberg, Zarah; Stepnov, Anton; Tesei, Giulio; Wang, Yong; Buchinger, Edith; Kristiansen, Sandra. (2023) The effect of linker conformation on performance and stability of a two-domain lytic polysaccharide monooxygenase. Journal of Biological Chemistry
Vitenskapelig artikkel
Forsberg, Zarah; Courtade, Gaston. (2022) On the impact of carbohydrate-binding modules (CBMs) in lytic polysaccharide monooxygenases (LPMOs). Essays in Biochemistry
Vitenskapelig oversiktsartikkel/review
Hellesnes, Kristina Naasen; Vijayaraj, Shunmathi; Fojan, Peter; Petersen, Evamaria; Courtade, Gaston. (2022) Biochemical Characterization and NMR Study of a PET-Hydrolyzing Cutinase from Fusarium solani pisi. Biochemistry
Vitenskapelig artikkel
Stepnov, Anton; Christensen, Idd Andrea; Forsberg, Zarah; Aachmann, Finn Lillelund; Courtade, Gaston; Eijsink, Vincent. (2021) The impact of reductants on the catalytic efficiency of a lytic polysaccharide monooxygenase and the special role of dehydroascorbic acid. FEBS Letters
Vitenskapelig artikkel
Madland, Eva; Forsberg, Zarah; Wang, Yong; Lindorff-Larsen, Kresten; Niebisch, Axel; Modregger, Jan. (2021) Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus. Journal of Biological Chemistry
Vitenskapelig artikkel
Courtade, Gaston; Ciano, Luisa; Paradisi, Alessandro; Lindley, Peter J.; Forsberg, Zarah; Sørlie, Morten. (2020) Mechanistic basis of substrate–O2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated NMR/EPR study. Proceedings of the National Academy of Sciences of the United States of America
Vitenskapelig artikkel
Guerrero-Garzón, Jaime Felipe; Madland, Eva; Zehl, Martin; Singh, Madhurendra; Rezaei, Shiva; Aachmann, Finn Lillelund. (2020) Class IV lasso peptides synergistically induce proliferation of cancer cells and sensitize them to doxorubicin. iScience
Vitenskapelig artikkel
Christensen, Idd Andrea; Eijsink, Vincent; Aachmann, Finn Lillelund; Courtade, Gaston. (2020) 1H, 13C, 15N resonance assignment of the apo form of the small, chitin-active lytic polysaccharide monooxygenase JdLPMO10Afrom Jonesia denitrificans. Biomolecular NMR Assignments
Vitenskapelig artikkel
Forsberg, Zarah; Sørlie, Morten; Petrovic, Dejan; Courtade, Gaston; Aachmann, Finn Lillelund; Vaaje-Kolstad, Gustav. (2019) Polysaccharide degradation by lytic polysaccharide monooxygenases. Current Opinion in Structural Biology
Vitenskapelig oversiktsartikkel/review
Courtade, Gaston; Forsberg, Zarah; Heggset, Ellinor Bævre; Eijsink, Vincent; Aachmann, Finn Lillelund. (2018) The carbohydrate-binding module and linker of a modular lytic polysaccharide monooxygenase promote localized cellulose oxidation. Journal of Biological Chemistry
Vitenskapelig artikkel
Kitaoku, Yoshihito; Courtade, Gaston; Petrovic, Dejan; Fukamizo, Tamo; Eijsink, Vincent; Aachmann, Finn Lillelund. (2018) Resonance assignments for the apo-form of the cellulose-active lytic polysaccharide monooxygenase TaLPMO9A. Biomolecular NMR Assignments
Vitenskapelig artikkel
Petrovic, Dejan; Bissaro, Bastien; Chylenski, Piotr; Skaugen, Morten; Sørlie, Morten; Jensen, Marianne Slang. (2018) Methylation of the N-terminal histidine protects a lytic polysaccharide monooxygenase from auto-oxidative inactivation. Protein Science
Vitenskapelig artikkel
Courtade, Gaston; Le, Simone Balzer; Sætrom, Gerd Inger; Brautaset, Trygve; Aachmann, Finn Lillelund. (2017) A novel expression system for lytic polysaccharide monooxygenases. Carbohydrate Research
Vitenskapelig artikkel
Courtade, Gaston; Forsberg, Zarah; Vaaje-Kolstad, Gustav; Eijsink, Vincentius Gerardus Henricus; Aachmann, Finn Lillelund. (2017) Chemical shift assignments for the apo-form of the catalytic domain, the linker region, and the carbohydrate-binding domain of the cellulose-active lytic polysaccharide monooxygenase ScLPMO10C. Biomolecular NMR Assignments
Vitenskapelig artikkel
Crasson, Oscar; Courtade, Gaston; Leonard, Raphael R; Aachmann, Finn Lillelund; Legrand, Francois; Parente, Raffaella. (2017) Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who’s Leading HCHT’s Biological Function. Scientific Reports
Vitenskapelig artikkel
Courtade, Gaston; Wimmer, Reinhard; Dimarogona, Maria; Sandgren, Mats; Eijsink, Vincent; Aachmann, Finn Lillelund. (2016) Backbone and side-chain 1H, 13C, and 15N chemical shift assignments for the apo-form of the lytic polysaccharide monooxygenase NcLPMO9C. Biomolecular NMR Assignments
Vitenskapelig artikkel
Courtade, Gaston; Wimmer, Reinhard; Kjendseth, Åsmund Røhr; Preims, Marita; Felice, Alfons K.G.; Dimarogona, Maria. (2016) Interactions of a fungal lytic polysaccharide monooxygenase with β-glucan substrates and cellobiose dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America
Vitenskapelig artikkel
Courtade, Gaston; Balzer, Simone; Forsberg, Zarah; Vaaje-Kolstad, Gustav; Eijsink, Vincent; Aachmann, Finn Lillelund. (2015) 1H, 13C, 15N resonance assignment of the chitin-active lytic polysaccharide monooxygenase BlLPMO10A from Bacillus licheniformis. Biomolecular NMR Assignments
Vitenskapelig artikkel
Gałęcki, Krystian; Courtade, Gaston; McFall, Aisling; Teixeira, Renata Prieschl; Grgic, Maja; Esteve-Sistere, Marta. (2013) Experimental and theoretical investigation of drotaverine binding to bovine serum albumin. Biotechnology and Food Science
Vitenskapelig artikkel

Del av bok/rapport

Courtade, Gaston; Aachmann, Finn Lillelund. (2019) Chitin-Active Lytic Polysaccharide Monooxygenases. Springer
Faglig kapittel

Rapport

Courtade, Gaston; Brautaset, Trygve; Aachmann, Finn Lillelund. (2018) An NMR investigation of lytic polysaccharide monooxygenases . Doktoravhandlinger ved NTNU (337)
Doktorgradsavhandling
Courtade, Gaston; Skjåk-Bræk, Gudmund; Aachmann, Finn Lillelund. (2014) Structural Investigation of a Lytic Polysaccharide Monooxygenase by NMR Spectroscopy . NTNU
Mastergradsoppgave

PRODUKT

Courtade, Gaston; Christensen, Bjørn E.; Ulset, Ann-Sissel Teialeret. (2014) Video demonstration of Biopolymers lab exercises.
Digitale læremidler

Språkvelger