Tone Frost Bathen

Professor

Institutt for sirkulasjon og bildediagnostikk Fakultet for medisin og helsevitenskap

tone.f.bathen@ntnu.no 73551355 95021097

MTFS, del 1, Øya

MR Cancer gruppen studerer funksjonelle og metabolske egenskaper i kreft ved hjelp av magnetisk resonans (MR) avbildning og spektroskopi. Ved å utvikle, anvende og optimalisere MR metodikk (i kombinasjon med andre molekylære metoder) for å karakterisere sykdom, er vårt mål å etablere bedre diagnostiske metoder som har prognostisk verdi (i.e. etablerere og validere biomarkører), og som kan stratifisere pasienter til riktig behandling. Våre to største fokusområder er brystkreft og prostatakreft, og vi jobber med vevsprøver og biofluids fra store biobanker, prekliniske dyremodeller og kliniske pasientstudier. I tillegg driver gruppen utstrakt biomedisinsk forskning basert på MR-metodikk i bred forstand; vi er involvert i flere studier med problemstillinger knyttet til hjerte-karsykdom, svangerskapsforgiftning og utprøving av nye kontrastmidler.

Publikasjoner registrert i PubMed:

https://www.ncbi.nlm.nih.gov/pubmed/?term=Bathen+TF

Vitenskapelig, faglig og kunstnerisk arbeid

Et utvalg av nyere tidsskriftspublikasjoner, kunstneriske produksjoner, bok, inklusiv bokdeler og rapport-del. Se alle publikasjoner i databasen

2021

Andersen, Maria Karoline; Høiem, Therese Stork; Claes, Britt S.R.; Balluff, Benjamin; Marta, Martin-Lorenzo; Richardsen, Elin; Krossa, Sebastian; Bertilsson, Helena; Heeren, Ron M.A.; Rye, Morten Beck; Giskeødegård, Guro F.; Bathen, Tone Frost; Tessem, May-Britt. (2021) Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI. Cancer & Metabolism.
Jones, Paul Remy; Rajalahti, Tarja; Resaland, Geir Kåre; Aadland, Eivind; Steene-Johannessen, Jostein; Anderssen, Sigmund Alfred; Bathen, Tone Frost; Andreassen, Trygve; Kvalheim, Olav Martin; Ekelund, Ulf. (2021) Cross-sectional and prospective associations between aerobic fitness and lipoprotein particle profile in a cohort of Norwegian schoolchildren. Atherosclerosis. vol. 321.

2020

Andersen, Maria Karoline; Krossa, Sebastian; Høiem, Therese Stork; Buchholz, Rebecca; Claes, Britt S.R.; Balluff, Benjamin; Ellis, Shane R.; Richardsen, Elin; Bertilsson, Helena; Heeren, Ron M.A.; Bathen, Tone Frost; Karst, Uwe; Giskeødegård, Guro F.; Tessem, May-Britt. (2020) Simultaneous detection of zinc and its pathway metabolites using MALDI MS imaging of prostate tissue. Analytical Chemistry. vol. 92 (4).
Andreassen, Maren Marie Sjaastad; Rodriguez-Soto, Ana; Conlin, CC; Vidic, Igor; Seibert, TM; Wallace, AM; Zare, S; Kuperman, J; Abudu, B; Ahn, GS; Hahn, M; Jerome, Neil Peter; Østlie, Agnes; Bathen, Tone Frost; Ojeda-Fournier, H; Goa, Pål Erik; Rakow-Penner, Rebecca; Dale, AM. (2020) Discrimination of Breast Cancer from Healthy Breast Tissue Using a Three-component Diffusion-weighted MRI Model. Clinical Cancer Research. vol. 27.
Liu, Jingjing; van der Smissen, Wendy J. C. Prager; Collee, Margriet J.; Bolla, Manjeet K.; Wang, Qin; Kristensen, Vessela N.; Sahlberg, Kristine Kleivi; Børresen-Dale, Anne-Lise; Ottestad, Lars; Kåresen, Rolf; Schlichting, Ellen; Holmen, Marit Muri; Sauer, Torill; Engebråten, Olav; Haakensen, Vilde Drageset; Naume, Bjørn; Fosså, Alexander; Kiserud, Cecilie E.; Reinertsen, Kristin Valborg; Helland, Åslaug; Riis, Margit; Geisler, Jürgen; Grenaker, Grethe Irene; Bathen, Tone Frost; Garred, Øystein; Sørlie, Therese; Borgen, Elin; Fritzman, Britt; Geitvik, Gry; Hofvind, Solveig; Langerød, Anita; Lingjærde, Ole Christian; Mælandsmo, Gunhild Mari; Russnes, Hege Elisabeth Giercksky; Skjerven, Helle; Michailidou, Kyriaki; Dennis, Joe; Ahearn, Thomas U.; Aittomaki, Kristiina; Ambrosone, Christine B.; Andrulis, Irene L.; Anton-Culver, Hoda; Arndt, Volker; Arnold, Norbert; Aronson, Kristan J.; Auvinen, Päivi; Augustinsson, Annelie; Becher, Heiko; Beckmann,, Matthias W.; Behrens, Sabine; Bermisheva, Marina; Bernstein, Leslie; Bogdanova, Natalia V.; Bogdanova-Markov, Nadja; Bojesen, Stig E.; Brauch, Hiltrud; Brenner, Hermann; Briceno, Ignacio; Brucker, Sara Y.; Bruening, Thomas; Burwinkel, Barbara; Cai, Qiuyin; Cai, Hui; Campa, Daniele; Canzian, Federico; Castelao, Jose E.; Chang-Claude, Jenny; Chanock, Stephen J.; Choi, Ji-Yeob; Christiaens, Melissa; Clarke, Christine L.; Couch, Fergus J.; Czene, Kamila; Daly, Mary B.; Devilee, Peter; dos-Santos-Silva, Isabel; Dwek, Miriam; Eccles, Diana M.; Eliassen, Heather A.; Hooning, Maartje J.; Martens, John W. M.; Hollestelle, Antoinette. (2020) Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk. Scientific Reports. vol. 10:9688 (1).
Samanipour, Saer; Reid, Malcolm J; Rundberget, Jan Thomas; Frost, Tone K.; Thomas, Kevin V. (2020) Concentration and Distribution of Naphthenic Acids in the Produced Water from Offshore Norwegian North Sea Oilfields. Environmental Science and Technology. vol. 54 (5).
Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Johansen, Håkon; Steen, Per Arvid; Langørgen, Sverre; Aksnessæther, Bjørg Yksnøy; Indrebø, Gunnar; Sjøbakk, Torill Eidhammer; Tessem, May-Britt; Moestue, Siver Andreas; Knobel, Heidi; Tandstad, Torgrim; Bertilsson, Helena; Solberg, Arne; Bathen, Tone Frost. (2020) Detection of recurrent prostate cancer with 18F-Fluciclovine PET/MRI. Frontiers in Oncology. vol. 10:582092.
Sunoqrot, Mohammed R. S.; Nketiah, Gabriel Addio; Selnæs, Kirsten Margrete; Bathen, Tone Frost; Elschot, Mattijs. (2020) Automated reference tissue normalization of T2-weighted MR images of the prostate using object recognition. Magnetic Resonance Materials in Physics, Biology and Medicine.
Sunoqrot, Mohammed R. S.; Selnæs, Kirsten Margrete; Sandsmark, Elise; Nketiah, Gabriel Addio; Zavala-Romero, Olmo; Stoyanova, Radka; Bathen, Tone Frost; Elschot, Mattijs. (2020) A quality control system for automated prostate segmentation on T2-weighted MRI. Diagnostics (Basel). vol. 10 (9).
Vidic, Igor; Egnell, Liv Elisabet; Jerome, Neil Peter; White, Nathan; Karunamuni, Roshan; Rakow-Penner, Rebecca; Dale, Anders M.; Bathen, Tone Frost; Goa, Pål Erik. (2020) Modeling the diffusion-weighted imaging signal for breast lesions in the b = 200 to 3000 s/mm 2 range: quality of fit and classification accuracy for different representations. Magnetic Resonance in Medicine. vol. 84 (2).

2019

Andersen, Maria Karoline; Krossa, Sebastian; Høiem, Therese Stork; Buchholz, Rebecca; Claes, Britt S.R.; Balluff, Benjamin; Ellis, Shane; Richardsen, Elin; Bertilsson, Helena; Bathen, Tone Frost; Karst, Uwe; Giskeødegård, Guro; Tessem, May-Britt. (2019) Simultaneous detection of the cancer biomarkers zinc and citrate in prostate cancer tissue using mass spectrometry imaging. European Urology. Supplement. vol. 18 (8).
Andreassen, Maren Marie Sjaastad; Goa, Pål Erik; Sjøbakk, Torill Eidhammer; Hedayati, Roja; Eikesdal, Hans Petter; Deng, Callie; Østlie, Agnes; Lundgren, Steinar; Bathen, Tone Frost; Jerome, Neil Peter. (2019) Semi-automatic segmentation from intrinsically-registered 18F-FDG-PET/MRI for treatment response assessment in a breast cancer cohort: comparison to manual DCE-MRI. Magnetic Resonance Materials in Physics, Biology and Medicine. vol. 33.
Austdal, Marie; Brettas Silva, Gabriela; Bowe, Sophie; Thomsen, Liv Cecilie Vestrheim; Tangerås, Line Haugstad; Bjørge, Line; Bathen, Tone Frost; Iversen, Ann-Charlotte. (2019) Metabolomics identifies placental dysfunction and confirms Flt-1 biomarker specificity. Pregnancy Hypertension. vol. 17.
Austdal, Marie; Silva, Gabriela; Bowe, Sophie; Thomsen, Liv Cecilie Vestrheim; Tangerås, Line Haugstad; Bjørge, Line; Bathen, Tone Frost; Iversen, Ann-Charlotte. (2019) Metabolomics identifies placental dysfunction and confirms Flt-1 (FMS-like tyrosine kinase receptor 1) biomarker specificity. Hypertension. vol. 74 (5).
Billdal, Daniel Chen; While, Peter Thomas; Selnæs, Kirsten Margrete; Sunoqrot, Mohammed; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost; Elschot, Mattijs. (2019) Relative enhanced diffusivity in prostate cancer: Protocol optimization and diagnostic potential. Journal of Magnetic Resonance Imaging.
Chronaiou, Ioanna; Giskeødegård, Guro F.; Goa, Pål Erik; Teruel, Jose; Hedayati, Roja; Lundgren, Steinar; Huuse, Else Marie; Pickles, Martin D.; Gibbs, Peter; Sitter, Beathe; Bathen, Tone Frost. (2019) Feasibility of contrast-enhanced MRI derived textural features to predict overall survival in locally advanced breast cancer. Acta Radiologica.
Debik, Julia Barbara; Euceda, Leslie R.; Lundgren, Steinar; Gythfeldt, Hedda; Garred, Øystein; Borgen, Elin; Engebråten, Olav; Bathen, Tone Frost; Giskeødegård, Guro F.. (2019) Assessing treatment response and prognosis by serum and tissue metabolomics in breast cancer patients. Journal of Proteome Research. vol. 18 (10).
Egnell, Liv Elisabet; Vidic, Igor; Jerome, Neil Peter; Bofin, Anna M.; Bathen, Tone Frost; Goa, Pål Erik. (2019) Stromal collagen content in breast tumors correlates with in vivo diffusion-weighted imaging: A comparison of multi b-value DWI with histologic specimen from benign and malignant breast lesions. Journal of Magnetic Resonance Imaging.
Elschot, Mattijs; Selnæs, Kirsten Margrete; Langørgen, Sverre; Johansen, Håkon; Bertilsson, Helena; Tandstad, Torgrim; Bathen, Tone Frost. (2019) Prostate-specific membrane antigen PET/magnetic resonance imaging for the planning of salvage radiotherapy in patients with prostate cancer with biochemical recurrence after radical prostatectomy. PET Clinics. vol. 14 (4).
Giskeødegård, Guro F.; Andreassen, Trygve; Bertilsson, Helena; Tessem, May-Britt; Bathen, Tone Frost. (2019) The effect of sampling procedures and day-to-day variations in metabolomics studies of biofluids. Analytica Chimica Acta. vol. 1081.

Tone Frost Bathen

Bakgrunn og aktiviteter

Vitenskapelig, faglig og kunstnerisk arbeid

2021

2020

2019

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