Duan Chen

Professor

Institutt for klinisk og molekylær medisin Fakultet for medisin og helsevitenskap

duan.chen@ntnu.no 98409675 72573320

Laboratoriesenteret, 231.03.068, Øya, Erling Skjalgssons gt 1

duan.chen@ntnu.no

Prof. Duan Chen (Dr. Med.) er forskningsgruppeleder i forskningsgruppen for eksperimentell kirurgi ved Institutt for klinisk og molekylær medisin (IKOM) ved Fakultet for medisin og helsevitenskap, NTNU. Han ble uteksaminert fra Lunds universitet i Sverige, er professor ved NTNU og medlemmer i Norges Tekniske Vitenskapsakademi og det Kongelige Norske Videnskabers Selskabs Akademi. Han var president for gastrointestinal seksjon i International Union of Basic and Clinical Pharmacology (IUPHAR), og var leder for en arbeidspakke i EU-prosjektet “Understanding food-gut-brain mechanisms across the lifespan in the regulation of hunger and satiety for health” i det 7. europeiske rammeprogrammet. Han er medlem av styringsråd av International Regulatory Peptide Society (IRPS), og redaktør av Scandinavian Journal of Gastroenterology.

Vennligst se lenkene under for flere detaljer om hans forskning

http://www.ntnu.no/dmf/ikm/molbiol

http://www.ntnu.no/dmf/ikm/eksperimentell-kirurgi

http://www.ntnu.no/dmf/ikm/eksperimentell_pagaende-forskning

Vitenskapelig, faglig og kunstnerisk arbeid

Et utvalg av nyere tidsskriftspublikasjoner, kunstneriske produksjoner, bok, inklusiv bokdeler og rapport-del. Se alle publikasjoner i databasen

Tidsskriftspublikasjoner

Eiden, Lee E.; Gundlach, Andrew L.; Grinevich, Valery; Lee, Mary R.; Mecawi, André S.; Chen, Duan; Buijs, Ruud M.; Hernández, Vito S.; Fajardo-Dolci, Germán; Zhang, Li-Mei. (2020) Regulatory peptides and systems biology: A new era of translational and reverse-translational neuroendocrinology. Journal of neuroendocrinology. vol. 00:e12844.
Guida, Claudia; Stephen, Sam D.; Watson, Michael; Dempster, Niall; Larraufie, Pierre; Marjot, Thomas; Cargill, Tamsin; Rickers, Lisa; Pavlides, Michael; Tomlinson, Jeremy; Cobbold, Jeremy F.L.; Zhao, Chun-Mei; Chen, Duan; Gribble, Fiona M; Reimann, Frank; Gillies, Richard; Sgromo, Bruno; Rorsman, Patrik; Ryan, John D; Ramracheya, Reshma D.. (2019) PYY plays a key role in the resolution of diabetes following bariatric surgery in humans. EBioMedicine. vol. 40.
Chen, Duan; Ayala, Gustavo E. (2018) Innervating Prostate Cancer. New England Journal of Medicine. vol. 378 (7).
Guida, Claudia; McCulloch, Laura J.; Godazgar, Mahdieh; Stephen, Sam D.; Baker, Charlotte; Basco, Davide; Dong, Jiawen; Chen, Duan; Clark, Anne; Ramracheya, Reshma D.. (2018) Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY. Diabetes, obesity and metabolism. vol. 20 (3).
Olsen, Magnus Kringstad; Johannessen, Helene; Ramracheya, Reshma; Zhao, Chun-Mei; Chen, Duan. (2018) New approaches for weight loss: Experiments using animal models. Current pharmaceutical design. vol. 24 (18).
Zhao, Chun-Mei; Rabben, Hanne-Line; Zhu, Yanping; Olsen, Magnus Kringstad; Wang, Zhiqiang; Hao, Yanpeng; Cai, Xing; Fonseca, Davi de Miranda; Sharma, Animesh; Li, Mingna; Zhihong, Zhang; Slupphaug, Geir; Wang, Timothy Cragin; Chen, Duan. (2018) 390 - A New Treatment for Pancreatic Cancer: Targeting Nervecancer Cell Crosstalk. Gastroenterology. vol. 154.
Hayakawa, Yoku; Sakitani, Kosuke; Konishi, Mitsuru; Asfaha, Samuel; Niikura, Ryota; Tomita, Hiroyuki; Renz, Bernhard W.; Tailor, Yagnesh; Macchini, Marina; Middelhoff, Moritz; Jiang, Zhengyu; Tanaka, Takayuki; Dubeykovskaya, Zinaida A.; Kim, Woosook; Chen, Xiaowei; Urbanska, Aleksandra M.; Nagar, Karan; Westphalen, Christoph B.; Quante, Michael; Lin, Chyuan-Sheng; Gershon, Michael D.; Hara, Akira; Zhao, Chun-Mei; Chen, Duan; Worthley, Daniel L.; Koike, Kazuhiko; Wang, Timothy C.. (2017) Nerve growth factor promotes gastric tumorigenesis through aberrant cholinergic signaling. Cancer Cell. vol. 31 (1).
Olsen, Magnus Kringstad; Choi, Man Hung; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2017) Time-restricted feeding on weekdays restricts weight gain: A study using rat models of high-fat diet-induced obesity. Physiology and Behavior. vol. 173.
Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens; van der Plasse, Geoffrey; Adan, Roger; Kulseng, Bård Eirik; Ben-Menachem, Elinor; Zhao, Chun Mei; Chen, Duan. (2016) Vagal blocking for obesity control: a possible mechanism-of-action. Obesity Surgery. vol. 27 (1).
Cai, Xing; Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Lundgren, Steinar; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2016) A Potential New Regimen (“Tricyclie”) for Treatment of Gastric Cancer: Targeting Glutamine-Dependent Wnt/β-Catenin-mTOR Signaling. Gastroenterology. vol. 150 (4).
Chen, Duan; Olsen, Magnus Kringstad; Strømmen, Magnus; Johannessen, Helene; Bjøru, Hege Tevik; Salater, Sissel; Johnsen, Gjermund; Mårvik, Ronald; Zhao, Chun-Mei; Kulseng, Bård Eirik. (2016) Intragastric Injection of Botulinum Toxin a to Treat Obesity: Mechanism of Action and a Randomized, Double-Blind, Placebo-Controlled Phase II Trial With Open-Label Extension Study. Gastroenterology. vol. 150 (4).
Dubeykovskaya, Z; Si, Y; Chen, X; Worthley, DL; Renz, BW; Urbanska, AM; Hayakawa, Y; Xu, T; Westphalen, CB; Dubeykovskiy, A; Chen, Duan; Friedman, RA; Asfaha, S; Nagar, S; Tailor, Y; Muthupalani, S; Fox, JG; Kitajewski, J; Wang, Timothy C.. (2016) Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nature Communications. vol. 7 (10517).
Olsen, Magnus Kringstad; Johannessen, Helene; Cassie, Nikki; Barrett, Perry; Takeuchi, Koji; Kulseng, Bård Eirik; Chen, Duan; Zhao, Chun-Mei. (2016) Steady-state energy balance in animal models of obesity and weight loss. Scandinavian Journal of Gastroenterology. vol. 52 (4).
Rabben, Hanne-Line; Zhao, Chun-Mei; Hayakawa, Yoku; Wang, Timothy C.; Chen, Duan. (2016) Vagotomy and gastric tumorigenesis. Current Neuropharmacology. vol. 14 (8).
Ramracheya, Reshma D.; McCulloch, Laura J.; Clark, Anne; Wiggins, David; Johannessen, Helene; Olsen, Magnus Kringstad; Cai, Xing; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery. Cell reports. vol. 15 (5).
Ramracheya, Reshma; McCulloch, Laura J.; Clark, Anne; Olsen, Magnus Kringstad; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) Roux-En-Y Gastric Bypass Surgery Restores Impaired Islet Architecture and Function in Type-2 Diabetes by Elevation of Plasma PYY. Gastroenterology. vol. 150 (4).
Øverby, Anders; Rabben, Hanne-Line; Takahashi, Tetsufumi; Zhao, Chun Mei; Matsui, Hidenori; Nakamura, Masahiko; Chen, Duan. (2016) Possible mechanism-of-action of naturally occurring isothiocyanates in chemoprevention and adjuvant chemotherapy for gastric cancer. Gastroenterology.
Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2015) 565Glutamine Metabolism As a Therapeutic Target for Gastric Cancer: Effects of Vagotomy Gastroenterology,Volume 148, Issue 4, Supplement 1, April 2015, Pages S-565–S-566. Gastroenterology. vol. 148 (4).
Boyce, Malcolm; Dowen, Sally; Turnbull, Gillian; van den Berg, Frans; Zhao, Chun-Mei; Chen, Duan; Black, James. (2015) Effect of netazepide, a gastrin/CCK2 receptor antagonist, on gastric acid secretion and rabeprazole-induced hypergastrinaemia in healthy subjectshypergastrinaemia in healthy subjects. British Journal of Clinical Pharmacology. vol. 79 (5).
Hayakawa, Yoku; Asfaha, Samuel; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor,, Yagnesh H.; Nagar,, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF Promotes Gastrointestinal Cancer Development Through Tumor-Associated Neurogenesis. Gastroenterology. vol. 148 (4).

Duan Chen

Bakgrunn og aktiviteter

Vitenskapelig, faglig og kunstnerisk arbeid

Tidsskriftspublikasjoner

Lenker

Språkvelger