2026

• Lund, Simen Jervell; Petersen, Agnes Beenfeldt; Areali, Antonia; Brautaset, Trygve; Aachmann, Finn Lillelund; Pérez-García, Fernando. (2026) Heterologous expression and functional characterization of two alginate lyases in corynebacterium glutamicum. Systems Microbiology and Biomanufacturing
  Vitenskapelig artikkel
• Irla, Marta; Brito, Luciana Fernandes; Langlo, Jesper; Wohlers, Carsten; Benninghaus, Leonie; Heid, Chantel; Wendisch, Volker F.; Schmid, Jochen; Brautaset, Trygve. (2026) Development of a markerless tool for targeted chromosome modification in the thermophilic and methylotrophic bacterium Bacillus methanolicus. Microbial Cell Factories
  Vitenskapelig artikkel

2025

• Fernandes de Brito, Luciana; Luciano, Davide; Irla, Marta Katarzyna; Virant, David; Courtade, Gaston; Brautaset, Trygve. (2025) Identification of MscS as a Key L-Glutamate Exporter in Bacillus methanolicus. Microbial Biotechnology
  Vitenskapelig artikkel
• Fernandes de Brito, Luciana; Aas, Ane Bræin; Rudberg, Rosa Jodalen; Brautaset, Trygve; Perez Garcia, Fernando. (2025) Production of the Antimicrobial Roseoflavin With Genetically Engineered Corynebacterium glutamicum. Microbial Biotechnology
  Vitenskapelig artikkel
• Fernandes de Brito, Luciana; Arampu, Adshaha; Perez Garcia, Fernando; Kaya, Fatma Ece Altınışık; Sayar, Nihat Alpagu; Akbulut, Berna Sariyar; Brautaset, Trygve. (2025) Model-based engineering of Bacillus methanolicus towards de novo polyamine bioproduction from methanol. New Biotechnology
  Vitenskapelig artikkel
• Fernandes de Brito, Luciana; Brautaset, Trygve. (2025) Tools and Strategies for Engineering Bacillus methanolicus: A Versatile Thermophilic Platform for Sustainable Bioproduction from Methanol and Alternative Feedstocks. Synthetic Biology and Engineering
  Vitenskapelig oversiktsartikkel
• Fernandes de Brito, Luciana; Frøystad, Monica G.; Vandenhove, Anna Haug; Brautaset, Trygve; Perez Garcia, Fernando. (2025) Red seaweed-based bioprocesses with Corynebacterium glutamicum. Bioresource Technology Reports
  Vitenskapelig artikkel
• Irla, Marta Katarzyna; Nærdal, Ingemar; Virant, David; Brautaset, Trygve; Busche, Tobias; Goranovič, Dušan; Haupka, Carsten; Heux, Stéphanie; Kosec, Gregor; Rückert-Reed, Christian. (2025) Systems-level analysis provides insights on methanol-based production of L-glutamate and its decarboxylation product γ-aminobutyric acid by Bacillus methanolicus. Metabolic Engineering
  Vitenskapelig artikkel

2024

• Klein, Vivien Jessica; Troøyen, Susanne Hansen; Fernandes de Brito, Luciana; Courtade, Gaston; Brautaset, Trygve; Irla, Marta Katarzyna. (2024) Identification and characterization of a novel formaldehyde dehydrogenase in Bacillus subtilis. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Bastem, Gülsüm Merve; Sayar, Nihat Alpagu; Fernandes de Brito, Luciana; Brautaset, Trygve; Virant, David; Akbulut, Berna Sariyar. (2024) Development of a novel process towards an L-malate biorefinery using methanol as feedstock. Chemical engineering research & design
  Vitenskapelig artikkel
• Perez Garcia, Fernando; Fernandes de Brito, Luciana; Bakken, Thea Isabel; Brautaset, Trygve. (2024) Riboflavin overproduction from diverse feedstocks with engineered Corynebacterium glutamicum. Biofabrication
  Vitenskapelig artikkel
• Gamlund, Espen; Barra, Mathias; Brautaset, Trygve. (2024) Surrogati bør ikke straffes. Morgenbladet
  Kommentar

2023

• Bratlie, Sigrid; Alsheikh, Muath K; Brautaset, Trygve; Gamlund, Espen; Holst-Jensen, Arne; Tøndel, Camilla; Wargelius, Anna. (2023) Mer faglighet fra naturbevegelsen, takk. Klassekampen
  Kommentar
• Wargelius, Anna; Alsheikh, Muath K; Gamlund, Espen; Tøndel, Camilla; Bartmann, Aina; Holst-Jensen, Arne; Wickson, Fern; Bratlie, Sigrid; Jakobsen, Ingvild Ulrikke; Brautaset, Trygve. (2023) Genteknologi i en bærekraftig fremtid. Genteknologiutvalget - Norsk Offentlig Utredning (NOU)
  Forskningsrapport
• Klein, Vivien Jessica; Fernandes de Brito, Luciana; Perez Garcia, Fernando; Brautaset, Trygve; Irla, Marta Katarzyna. (2023) Metabolic engineering of thermophilic Bacillus methanolicus for riboflavin overproduction from methanol. Microbial Biotechnology
  Vitenskapelig artikkel
• Hesjedal, Maria Bårdsen; Brautaset, Trygve; Strand, Roger. (2023) Digital Life Norway - should biotechnology be transdisciplinary?.
  Vitenskapelig kapittel

2022

• Perez-Garcia, Fernando; Klein, Vivien Jessica; Fernandes de Brito, Luciana; Brautaset, Trygve. (2022) From Brown Seaweed to a Sustainable Microbial Feedstock for the Production of Riboflavin. Frontiers in Bioengineering and Biotechnology
  Vitenskapelig artikkel
• Klein, Vivien Jessica; Irla, Marta Katarzyna; Gil Lopez, Marina; Brautaset, Trygve; Fernandes de Brito, Luciana. (2022) Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy. Microorganisms
  Vitenskapelig oversiktsartikkel
• Naderi, Sheida; Visnes, Torkild; Brautaset, Trygve. (2022) Impact of DNA glycosylases on epigenetic regulation of gene expression via active DNA demethylation in human cells. Norges teknisk-naturvitenskapelige universitet
  Masteroppgave

2021

• Irla, Marta Katarzyna; Hakvåg, Sigrid; Brautaset, Trygve. (2021) Developing a riboswitch-mediated regulatory system for metabolic flux control in thermophilic bacillus methanolicus. International Journal of Molecular Sciences
  Vitenskapelig artikkel
• Khider, May Laura Kilano; Brautaset, Trygve; Irla, Marta Katarzyna. (2021) Methane monooxygenases: central enzymes in methanotrophy with promising biotechnological applications. World Journal of Microbiology & Biotechnology
  Vitenskapelig artikkel
• Stenseth, Nils Christian; Baalsrud, Helle Tessand; Jakobsen, Kjetill Sigurd; Brautaset, Trygve; Goksøyr, Anders; Jensen, Nina; Jørgensen, Trond Ø.; Raa, Jan; Sandve, Simen Rød. (2021) Havgenomet – bevaring og bærekraftig bruk av marine genetiske ressurser i Norge.
  Faglig kapittel
• Wendisch, Volker F.; Kosec, Gregor; Heux, Stéphanie; Brautaset, Trygve. (2021) Aerobic Utilization of Methanol for Microbial Growth and Production. Advances in Biochemical Engineering, Biotechnology
  Vitenskapelig oversiktsartikkel
• Fernandes de Brito, Luciana; Irla, Marta Katarzyna; Nærdal, Ingemar; Le, Simone Balzer; Baudoin, Delepine; Heux, Stéphanie; Brautaset, Trygve. (2021) Evaluation of Heterologous Biosynthetic Pathways for Methanol-Based 5-Aminovalerate Production by Thermophilic Bacillus methanolicus. Frontiers in Bioengineering and Biotechnology
  Vitenskapelig artikkel
• Brautaset, Trygve. (2021) Genteknologisk vaksine gir nytt håp. Genialt - Tidsskrift fra Bioteknologirådet
  Populærvitenskapelig artikkel

2020

• Brautaset, Trygve; Jonassen, Inge; Bösl, Korbinian; K, Torheim Norunn. (2020) På tide å sette av fem prosent av prosjektmidlene til datahåndtering?. Khrono.no
  Populærvitenskapelig artikkel
• Drejer, Eivind Bøe; Chan, Dennis; Haupka, Carsten; Wendisch, Volker F.; Brautaset, Trygve; Irla, Marta Katarzyna. (2020) Methanol-based acetoin production by genetically engineered Bacillus methanolicus. Green Chemistry
  Vitenskapelig artikkel
• Hans, Sebastian; Ulmer, Christian; Narayanan, Harini; Brautaset, Trygve; Krausch, Niels; Neubauer, Peter; Schaffl, Irmgard; Sokolov, Michael; Bournazou, Mariano Nicolas Cruz. (2020) Monitoring Parallel Robotic Cultivations with Online Multivariate Analysis. Processes
  Vitenskapelig artikkel
• Gawin, Agnieszka Maria; Ertesvåg, Helga; Hansen, Sine Alise Hartvigsen; Malmo, Jostein; Brautaset, Trygve. (2020) Translational regulation of periplasmic folding assistants and proteases as a valuable strategy to improve production of translocated recombinant proteins in Escherichia coli. BMC Biotechnology
  Vitenskapelig artikkel
• Gawin, Agnieszka Maria; Tietze, Lisa; Aarstad, Olav Andreas; Aachmann, Finn Lillelund; Brautaset, Trygve; Ertesvåg, Helga. (2020) Functional characterization of three Azotobacter chroococcum alginate-modifying enzymes related to the Azotobacter vinelandii AlgE mannuronan C-5-epimerase family. Scientific Reports
  Vitenskapelig artikkel
• Irla, Marta Katarzyna; Drejer, Eivind Bøe; Brautaset, Trygve; Hakvåg, Sigrid. (2020) Establishment of a functional system for recombinant production of secreted proteins at 50 °C in the thermophilic Bacillus methanolicus. Microbial Cell Factories
  Vitenskapelig artikkel
• Pfeifenschneider, Johannes; Markert, Benno; Stolzenberger, Jessica; Brautaset, Trygve; Wendisch, Volker F.. (2020) Transaldolase in Bacillus methanolicus: biochemical characterization and biological role in ribulose monophosphate cycle. BMC Microbiology
  Vitenskapelig artikkel
• Allahgholi, Leila; Sardari, Roya R.R.; Hakvåg, Sigrid; Ara, Kazi Z.G.; Kristjansdottir, Thordis Anna; Aasen, Inga Marie; Fridjonsson, Olafur H.; Brautaset, Trygve; Hreggvidsson, Gudmundur Oli; Karlsson, Eva Nordberg. (2020) Composition analysis and minimal treatments to solubilize polysaccharides from the brown seaweed Laminaria digitata for microbial growth of thermophiles. Journal of Applied Phycology
  Vitenskapelig artikkel
• Hakvåg, Sigrid; Nærdal, Ingemar; Heggeset, Tonje Marita Bjerkan; Kristiansen, Kåre Andre; Aasen, Inga Marie; Brautaset, Trygve. (2020) Production of Value-Added Chemicals by Bacillus methanolicus Strains Cultivated on Mannitol and Extracts of Seaweed Saccharina latissima at 50C. Frontiers in Microbiology
  Vitenskapelig artikkel

2019

• Brautaset, Trygve; Valla, Svein. (2019) Special Issue: Recombinant Protein Expression in Microorganisms. Microorganisms
  Vitenskapelig artikkel
• Schultenkamper, Kerstin; Fernandes de Brito, Luciana; Lopez, Marina Gil; Brautaset, Trygve; Wendisch, Volker F.. (2019) Establishment and application of CRISPR interference to affect sporulation, hydrogen peroxide detoxification, and mannitol catabolism in the methylotrophic thermophile Bacillus methanolicus. Applied Microbiology and Biotechnology
  Vitenskapelig artikkel
• Nærdal, Ingemar; Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2019) Corrigendum Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains. Microbial Biotechnology
  Korrigendum
• Irla, Marta Katarzyna; Heggeset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer; Brautaset, Trygve; Wendisch, Volker F.. (2019) Corrigendum: Genome-Based Genetic Tool Development for Bacillus methanolicus: Theta- and Rolling Circle-Replicating Plasmids for Inducible Gene Expression and Application to Methanol-Based Cadaverine Production. Frontiers in Microbiology
  Korrigendum
• Gawin, Agnieszka; Peebo, Karl; Sebastian, Hans; Ertesvåg, Helga; Irla, Marta Katarzyna; Neubauer, Peter; Brautaset, Trygve. (2019) Construction and characterization of broad-host-range reporter plasmid suitable for on-line analysis of bacterial host responses related to recombinant protein production. Microbial Cell Factories
  Vitenskapelig artikkel
• Schultenkämper, Kerstin; Fernandes de Brito, Luciana; López, Marina Gil; Brautaset, Trygve; Wendisch, Volker F.. (2019) Establishment and application of CRISPR interference to affect sporulation, hydrogen peroxide detoxification, and mannitol catabolism in the methylotrophic thermophile Bacillus methanolicus. Applied Microbiology and Biotechnology
  Vitenskapelig artikkel

2018

• Johansen, Finn-Eirik; Brautaset, Trygve; Aune, Marie Hjelmseth; Patriksson, Alexandra; Falkenberg, Liv Eggset; Kleppe, Rune; Dick, Gunnar; Strand, Berit Løkensgard; Eijsink, Vincent; Røyne, Anja. (2018) Centre for Digital Life Norway - Annual report 2017. Senter for Digialt Liv Norge
  Forskningsrapport
• Courtade, Gaston; Brautaset, Trygve; Aachmann, Finn Lillelund. (2018) An NMR investigation of lytic polysaccharide monooxygenases. Norges teknisk-naturvitenskapelige universitet
  Doktoravhandling
• Drejer, Eivind Bøe; Hakvåg, Sigrid; Irla, Marta Katarzyna; Brautaset, Trygve. (2018) Genetic Tools and Techniques for Recombinant Expression in Thermophilic Bacillaceae. Microorganisms
  Vitenskapelig oversiktsartikkel

2017

• Courtade, Gaston; Le, Simone Balzer; Sætrom, Gerd Inger; Brautaset, Trygve; Aachmann, Finn Lillelund. (2017) A novel expression system for lytic polysaccharide monooxygenases. Carbohydrate Research
  Vitenskapelig artikkel
• Brautaset, Trygve. (2017) Bioteknologi.
  Faglig kapittel
• Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2017) Methanol as a carbon substrate in the bio-economy: metabolic engineering of aerobic methylotrophic bacteria for production of value-added chemicals. Biofuels, Bioproducts and Biorefining
  Vitenskapelig oversiktsartikkel
• Irla, Marta; Nærdal, Ingemar; Brautaset, Trygve; Wendisch, Volker F.. (2017) Methanol-based γ-aminobutyric acid (GABA) production by genetically engineered Bacillus methanolicus strains. Industrial crops and products (Print)
  Vitenskapelig artikkel
• Nærdal, Ingemar; Netzer, Roman; Irla, Marta; Krog, Anne; Heggset, Tonje Marita Bjerkan; Wendisch, Volker F.; Brautaset, Trygve. (2017) L-lysine production by Bacillus methanolicus: Genome-based mutational analysis and L-lysine secretion engineering. Journal of Biotechnology
  Vitenskapelig artikkel
• Le, Simone Balzer; Heggset, Tonje Marita Bjerkan; Haugen, Tone; Nærdal, Ingemar; Brautaset, Trygve. (2017) 6-Phosphofructokinase and ribulose-5-phosphate 3-epimerase in methylotrophic Bacillus methanolicus ribulose monophosphate cycle. Applied Microbiology and Biotechnology
  Vitenskapelig artikkel
• Gawin, Agnieszka; Valla, Svein; Brautaset, Trygve. (2017) The XylS/Pm regulator/promoter system and its use in fundamental studies of bacterial gene expression, recombinant protein production and metabolic engineering. Microbial Biotechnology
  Vitenskapelig oversiktsartikkel

2016

• Irla, Marta; Heggset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer; Brautaset, Trygve; Wendisch, Volker F.. (2016) Genome-based genetic tool development for Bacillus methanolicus: Theta-and rolling circle-replicating plasmids for inducible gene expression and application to methanol-based cadaverine production. Frontiers in Microbiology
  Vitenskapelig artikkel
• Brautaset, Trygve. (2016) Syntetisk biologi - muligheter og trusler. Biolog
  Populærvitenskapelig artikkel
• Wimark, Odd-Gunnar; Brautaset, Trygve. (2016) Report: Synthetic biology - biosafety and contribution to addressing societal challenges Chapter 1: Synthetic Biology: Science, Experimental Approaches and Applications in Biotechnology. GenØk – Senter for biosikkerhet, Forskningsparken i Breivika, Postboks 6418, 9294 Tromsø
  Forskningsrapport
• Carnicer, Marc; Vieira, Gilles; Brautaset, Trygve; Portais, Jean-Charles; Heux, Stéphanie. (2016) Quantitative metabolomics of the thermophilic methylotroph Bacillus methanolicus. Microbial Cell Factories
  Vitenskapelig artikkel
• Liu, Bin; Ertesvåg, Helga; Aasen, Inga Marie; Vadstein, Olav; Brautaset, Trygve; Heggeset, Tonje Marita Bjerkan. (2016) Draft genome sequence of the docosahexaenoic acid producing thraustochytrid Aurantiochytrium sp. T66. Genomics Data
  Vitenskapelig artikkel
• Aasen, Inga Marie; Ertesvåg, Helga; Heggeset, Tonje Marita Bjerkan; Liu, Bin; Brautaset, Trygve; Vadstein, Olav; Ellingsen, Trond Erling. (2016) Thraustochytrids as production organisms for docosahexaenoic acid (DHA), squalene, and carotenoids. Applied Microbiology and Biotechnology
  Vitenskapelig oversiktsartikkel

2015

• Irla, Marta; Neshat, Armin; Brautaset, Trygve; Rückert, Christian; Kalinowski, Jörn; Wendisch, Volker F.. (2015) Transcriptome analysis of thermophilic methylotrophic Bacillus methanolicus MGA3 using RNA-sequencing provides detailed insights into its previously uncharted transcriptional landscape. BMC Genomics
  Vitenskapelig artikkel
• Müller, Jonas E.N.; Meyer, Fabian; Litsanov, Boris; Kiefer, Patrick; Potthoff, Eva; Heux, Stéphanie; Quax, Wim J.; Wendisch, Volker F.; Brautaset, Trygve; Portais, Jean-Charles. (2015) Engineering Escherichia coli for methanol conversion. Metabolic Engineering
  Vitenskapelig artikkel
• Almaas, Eivind; Brautaset, Trygve. (2015) Syntetisk biologi.
  Populærvitenskapelig kapittel
• Nærdal, Ingemar; Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F.. (2015) Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains. Microbial Biotechnology
  Vitenskapelig artikkel

2014

• Markert, Benno; Stolzenberger, Jessica; Brautaset, Trygve; Wendisch, Volker F.. (2014) Characterization of two transketolases encoded on the chromosome and the plasmid pBM19 of the facultative ribulose monophosphate cycle methylotroph Bacillus methanolicus. BMC Microbiology
  Vitenskapelig artikkel
• Müller, Jonas E.N.; Heggeset, Tonje Marita Bjerkan; Wendisch, Volker F.; Vorholt, Julia A.; Brautaset, Trygve. (2014) Methylotrophy in the thermophilic Bacillus methanolicus, basic insights and application for commodity production from methanol. Applied Microbiology and Biotechnology
  Vitenskapelig artikkel
• Müller, Jonas E.N.; Litsanov, Boris; Bortfeld-Miller, Miriam; Trachsel, Christian; Grossmann, Jonas; Brautaset, Trygve; Vorholt, Julia A.. (2014) Proteomic analysis of the thermophilic methylotroph Bacillus methanolicus MGA3. Proteomics
  Vitenskapelig artikkel
• Irla, Marta; Neshat, Armin; Winkler, Anika; Albersmeier, Andreas; Heggeset, Tonje Marita Bjerkan; Brautaset, Trygve; Kalinowski, Jörn; Wendisch, Volker F.; Rückert, Christian. (2014) Complete genome sequence of Bacillus methanolicus MGA3, a thermotolerant amino acid producing methylotroph. Journal of Biotechnology
  Vitenskapelig artikkel

2013

• Krog, Anne; Heggeset, Tonje Marita Bjerkan; Müller, Jonas E.N.; Kupper, Christiane E.; Schneider, Olha; Vorholt, Julia A.; Ellingsen, Trond Erling; Brautaset, Trygve. (2013) Methylotrophic Bacillus methanolicus encodes two chromosomal and one plasmid born NAD+ dependent methanol dehydrogenase paralogs with different catalytic and biochemical properties. PLOS ONE
  Vitenskapelig artikkel
• Krog, Anne; Heggeset, Tonje Marita Bjerkan; Ellingsen, Trond Erling; Brautaset, Trygve. (2013) Functional Characterization of Key Enzymes involved in L-Glutamate Synthesis and Degradation in the Thermotolerant and Methylotrophic Bacterium Bacillus methanolicus. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Kucharova, Veronika; Aakvik, Trine; Almaas, Eivind; Naas, Adrian Ertsås; Brautaset, Trygve; Valla, Svein. (2013) Non-Invasive Analysis of Recombinant mRNA Stability in Escherichia coli by a Combination of Transcriptional Inducer Wash-Out and qRT-PCR. PLOS ONE
  Vitenskapelig artikkel
• Heggeset, Tonje Marita Bjerkan; Kucharova, Veronika; Nærdal, Ingemar; Valla, Svein; Sletta, Håvard; Ellingsen, Trond Erling; Brautaset, Trygve. (2013) Combinatorial Mutagenesis and Selection of Improved Signal Sequences and Their Application for High-Level Production of Translocated Heterologous Proteins in Escherichia coli. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Balzer, Simone; Kucharova, Veronika; Megerle, Judith; Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2013) A comparative analysis of the properties of regulated promoter systems commonly used for recombinant gene expression in Escherichia coli. Microbial Cell Factories
  Vitenskapelig artikkel
• Berg, Laila; Aakvik, Trine; Valla, Svein; Brautaset, Trygve. (2013) Combinatorial Mutagenesis and Selection to Understand and Improve Yeast Promoters. Biomedical Research
  Vitenskapelig artikkel
• Kucharova, Veronika; Skancke, Jørgen; Brautaset, Trygve; Valla, Svein. (2013) Design and optimization of short DNA sequences that can be used as 5' fusion partners for high-level expression of heterologous genes in Escherichia coli. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Heider, Sabine; Peters-Wendisch, Petra; Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Brautaset, Trygve; Wendisch, Volker F.. (2013) Production and glucosylation of C50 and C40 carotenoids by metabolically engineered Corynebacterium glutamuicum. Applied Microbiology and Biotechnology
  Vitenskapelig artikkel
• Stolzenberger, J; Linder, SN; Persicke, M; Brautaset, Trygve; Wendisch, VF. (2013) Characterization of Fructose 1,6-Bisphosphatase and Sedoheptulose 1,7-Bisphosphatase from the Facultative Ribulose Monophosphate Cycle Methylotroph Bacillus methanolicus. Journal of Bacteriology
  Vitenskapelig artikkel
• Tøndervik, Anne; Balzer, Simone; Haugen, Tone; Sletta, Håvard; Rode, Marit; Lindmo, Karine; Ellingsen, Trond Erling; Brautaset, Trygve. (2013) High production of recombinant Norwegian salmonid alphavirus E1 and E2 proteins in Escherichia coli by fusion to secretion signal sequences and removal of hydrophobic domains. Biotechnology and Bioprocess Engineering
  Vitenskapelig artikkel

2012

• Heggeset, Tonje Marita; Krog, Anne; Balzer, Simone; Wentzel, Alexander; Ellingsen, Trond Erling; Brautaset, Trygve. (2012) Genome Sequence of Thermotolerant Bacillus methanolicus: Features and Regulation Related to Methylotrophy and Production of L-Lysine and L-Glutamate from Methanol. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Berg, Laila; Kucharova, Veronika; Bakke, Ingrid; Valla, Svein; Brautaset, Trygve. (2012) Exploring the 5 '-UTR DNA region as a target for optimizing recombinant gene expression from the strong and inducible Pm promoter in Escherichia coli. Journal of Biotechnology
  Vitenskapelig artikkel

2011

• Lale, Rahmi; Berg, Laila; Stuttgen, Friederike; Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Brautaset, Trygve; Aune, Trond Erik Vee; Valla, Svein. (2011) Continuous Control of the Flow in Biochemical Pathways through 5 ' Untranslated Region Sequence Modifications in mRNA Expressed from the Broad-Host-Range Promoter Pm. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2011) Broad-Host-Range Plasmid Vectors for Gene Expression in Bacteria.
  Vitenskapelig kapittel
• Brautaset, Trygve; Ellingsen, Trond Erling. (2011) Lysine: Industrial Uses and Production.
  Vitenskapelig kapittel
• Nærdal, Ingemar; Netzer, Roman; Ellingsen, Trond Erling; Brautaset, Trygve. (2011) Analysis and Manipulation of Aspartate Pathway Genes for L-Lysine Overproduction from Methanol by Bacillus methanolicus. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Brautaset, Trygve; Sletta, Håvard; Degnes, Kristin Fløgstad; Sekurova, Olga; Bakke, Ingrid; Volokhan, Olga; Andreassen, Trygve; Ellingsen, Trond Erling; Zotchev, Sergey. (2011) New nystatin-related antifungal polyene macrolides with altered polyol region generated via biosynthetic engineering of Streptomyces noursei. Applied and Environmental Microbiology
  Vitenskapelig artikkel

2010

• Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Degnes, Kristin F.; Netzer, Roman; Nærdal, Ingemar; Krog, Anne; Dillingham, Rick; Flickinger, Michael C.; Ellingsen, Trond Erling. (2010) Bacillus methanolicus pyruvate carboxylase and homoserine dehydrogenase I and II and their roles for L-lysine production from methanol at 50°C. Applied Microbiology and Biotechnology
  Vitenskapelig artikkel
• Aune, Trond Erik Vee; Bakke, Ingrid; Drabløs, Finn; Lale, Rahmi; Brautaset, Trygve; Valla, Svein. (2010) Directed evolution of the transcription factor XylS for development of improved expression systems. Microbial Biotechnology
  Vitenskapelig artikkel
• Netzer, Roman; Stafsnes, Marit Hallvardsdotter; Andreassen, Trygve; Goksøyr, Audun; Bruheim, Per; Brautaset, Trygve. (2010) Biosynthetic Pathway for g-Cyclic Sarcinaxanthin in Micrococcus luteus: Heterologous Expression and Evidence for Diverse and Multiple Catalytic Functions of C50 Carotenoid Cyclases. Journal of Bacteriology
  Vitenskapelig artikkel

2009

• Brautaset, Trygve; Lale, Rahmi; Valla, Svein. (2009) Minireview - Positively regulated bacterial expression systems. Microbial Biotechnology
  Vitenskapelig artikkel
• Jakobsen, Øyvind Mejdell; Brautaset, Trygve; Degnes, Kristin F.; Heggeset, Tonje M.B.; Balzer, Simone; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling. (2009) Overexpression of Wild-Type Aspartokinase Increases L-Lysine Production in the Thermotolerant Methylotrophic Bacterium Bacillus methanolicus. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Bakke, Ingrid; Berg, Laila; Aune, Trond Erik Vee; Brautaset, Trygve; Sletta, Håvard; Tøndervik, Anne; Valla, Svein. (2009) Random Mutagenesis of the Pm Promoter as a Powerful Strategy for Improvement of Recombinant-Gene Expression. Applied and Environmental Microbiology
  Vitenskapelig artikkel

2008

• Brautaset, Trygve. (2008) Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei. Chemistry and Biology
  Vitenskapelig artikkel
• Brautaset, Trygve; Sletta, Håvard; Nedal, Aina; Borgos, Sven Even F.; Degnes, Kristin F.; Bakke, Ingrid; Volokhan, Olga; Sekurova, Olga N.; Treshalin, Ivan D.; Mirchink, Elena P.. (2008) Improved Antifungal Polyene Macrolides via Engineering of the Nystatin Biosynthetic Genes in Streptomyces noursei. Chemistry and Biology
  Vitenskapelig artikkel

2007

• Nedal, Aina; Sletta, Håvard; Brautaset, Trygve; Borgos, Sven Even F.; Sekurova, Olga; Ellingsen, Trond E.; Zotchev, Sergey. (2007) Analysis of the mycosamine biosynthesis and attachment genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Brautaset, Trygve; Jakobsen, Øyvind Mejdell; Josefsen, Kjell D.; Flickinger, Michael C.; Ellingsen, Trond Erling. (2007) Bacillus methanolicus: a candidate for industrial production of amino acids from methanol at 50°C. Applied Microbiology and Biotechnology
  Vitenskapelig oversiktsartikkel
• Sletta, Håvard; Tøndervik, Anne; Hakvåg, Sigrid; Nedal, Aina; Aune, Trond Erik Vee; Aune, Randi; Evensen, G.; Valla, Svein; Ellingsen, Trond Erling; Brautaset, Trygve. (2007) The presence of N-terminal secretion signal sequences leads to strong stimulation of the total expression levels of three tested medically important proteins during high-cell-density cultivations of Escherichia coli. Applied and Environmental Microbiology
  Vitenskapelig artikkel

2006

• Borgos, Sven Even F.; Sletta, Håvard; Fjærvik, Espen; Brautaset, Trygve; Ellingsen, Trond Erling; Gulliksen, Ole-Martin; Zotchev, Sergey. (2006) Effect of glucose limitation and specific mutations in the module 5 enoyl reductase domains in the nystatin and amphotericin polyketide synthases on polyene macrolide biosynthesis. Archives of Microbiology
  Vitenskapelig artikkel
• Jakobsen, Øyvind Mejdell; Benichou, Aline; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling; Brautaset, Trygve. (2006) Upregulated transcription of plasmid and chromosomal ribulose monophosphate pathway genes is critical for methanol assimilation rate and methanol tolerance in the methylotrophic bacterium Bacillus methanolicus. Journal of Bacteriology
  Vitenskapelig artikkel

2005

• Jakobsen, OM; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling; Brautaset, Trygve. (2005) Plasmid-dependent methylotrophy and its significance for the Biology of thermotolerant bacterium Bacillus methanolicus. Journal of Biotechnology
  Konferanseabstract

2004

• Sletta, Håvard; Nedal, Aina; Aune, Trond Erik Vee; Hellebust, H.; Hakvåg, Sigrid; Aune, R.; Ellingsen, Trond Erling; Valla, Svein; Brautaset, Trygve. (2004) Broad-host-range plasmid pJB658 can be used for industrial-level production of a secreted host-toxic single-chain antibody fragment in Escherichia coli. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Sekurova, Olga; Brautaset, Trygve; Sletta, Håvard; Borgos, Sven Even F.; Jakobsen, OM; Ellingsen, Trond Erling; Strøm, Arne Reidar; Valla, Svein; Zotchev, Sergey. (2004) In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis. Journal of Bacteriology
  Vitenskapelig artikkel
• Brautaset, Trygve; Jakobsen, OM; Flickinger, Michael C.; Valla, Svein; Ellingsen, Trond Erling. (2004) Plasmid-dependent methylotrophy in thermotolerant Bacillus methanolicus. Journal of Bacteriology
  Vitenskapelig artikkel

2003

• Brautaset, Trygve; Williams, Mark; Dillingham, Richard; Flickinger, Michael. (2003) The role of the Bacillus methanolicus citrate synthase II gene, citY, in regulating the secretion of glutamate in L-lysine secreting mutants. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond Erling; Zotchev, Sergey. (2003) Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin synthesis in Streptomyces noursei. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Brautaset, Trygve; Borgos, Sven Even F.; Sletta, Håvard; Ellingsen, Trond E.; Zotchev, Sergey. (2003) Site-specific mutagenesis and domain substitutions in the loading module of the nystatin polyketide synthase, and their effects on nystatin biosynthesis in Streptomyces noursei. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Brautaset, Trygve; Williams, Mark D.; Dillingham, Richard D.; Kaufmann, Christine; Bennaars, Assumpta; Crabbe, Edward; Flickinger, Michael C.. (2003) Role of the Bacillus methanolicus citrate synthase II gene, citY, in regulating the secretion of glutamate in L-lysine-secreting mutants. Applied and Environmental Microbiology
  Vitenskapelig artikkel

2002

• Brautaset, Trygve; Bruheim, Per; Sletta, Håvard; Hagen, Lars; Ellingsen, Trond E.; Strøm, Arne Reidar; Valla, Svein; Zotchev, Sergey. (2002) Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455. Chemistry and Biology
  Vitenskapelig artikkel

2001

• Brautaset, Trygve; Zotchev, Sergey. (2001) Cloning and sequencing of a polyene antibiotic biosynthetic gene cluster. QIAGEN Newsletter
  Vitenskapelig artikkel

2000

• Winther-Larsen, Hanne C.; Josefsen, Kjell D.; Brautaset, Trygve; Valla, Svein. (2000) Parameters affecting gene expression from the Pm promoter in gram-negative bacteria. Metabolic Engineering
  Vitenskapelig artikkel
• Winther-Larsen, Hanne C.; Blatny, Janet M.; Valand, Bjørnar; Brautaset, Trygve; Valla, Svein. (2000) Pm promoter expression mutants and their use in broad-host-range RK2 plasmid vectors. Metabolic Engineering
  Vitenskapelig artikkel
• Brautaset, Trygve; Petersen, Steffen B.; Valla, Svein. (2000) In vitro determined kinetic properties of mutant phosphoglucomutases and their effects on sugar catabolism in Escherichia coli. Metabolic Engineering
  Vitenskapelig artikkel
• Brautaset, Trygve; Sekurova, Olga; Sletta, Håvard; Ellingsen, Trond E.; Strøm, Arne Reidar; Valla, Svein; Zotchev, Sergey. (2000) Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455 : analysis of the gene cluster and deduction of the biosynthetic pathway. Chemistry and Biology
  Vitenskapelig artikkel

1999

• Zotchev, Sergey; Brautaset, Trygve. (1999) Genetic manipulations of antibiotic-producing bacteria - an approach to creating new antibiotics. NBS-nytt
  Vitenskapelig artikkel
• Brautaset, Trygve. (1999) Enzyme Engineering. NBS-nytt
  Vitenskapelig artikkel
• Zotchev, Sergey; Brautaset, Trygve. (1999) Genetic manipulations of antibiotic-producing bacteria- an approach to creating new antibiotics. NBS-nytt
  Vitenskapelig artikkel

1998

• Brautaset, Trygve. (1998) Phosphoglucomutase and its mutant derivatives as models for studies of carbon flow in Escherichia coli. NTNU Trondheim Norwegian University of Science and Technology
  Doktoravhandling
• Brautaset, Trygve; Petersen, Steffen; Valla, Svein. (1998) An Experimental study on carbon flow in Escherichia coli as a function of kinetic properties and expression levels of the enzyme phosphoglucomutase. Biotechnology and Bioengineering
  Vitenskapelig artikkel

1997

• Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Karunakaran, Ponniah; Valla, Svein. (1997) Improved broad-host-range RK2 vectors useful for high and low regulated gene expression levels in gram-negative bacteria. Plasmid
  Vitenskapelig artikkel
• Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Haugan, Kåre; Valla, Svein. (1997) Construction and use of a versatile set of broad-host-range cloning an d expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Brautaset, Trygve. (1997) Construction and use of a versatile set of broad-host-range cloning and expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
  Vitenskapelig artikkel
• Blatny, Janet Martha; Karunakaran, Ponniah; Brautaset, Trygve; Knutsen, Torill Irene; Winther-Larsen, Hanne C.; Valla, Svein. (1997) New RK2 vectors useful in biotechnology and for analyses of RK2 replication and copy number control. Plasmid
  Vitenskapelig artikkel
• Blatny, Janet Martha; Brautaset, Trygve; Winther-Larsen, Hanne C.; Haugan, Kåre; Valla, Svein. (1997) Construction and use of a versatile set of broad-host-range cloning an d expression vectors based on the RK2 replicon. Applied and Environmental Microbiology
  Vitenskapelig artikkel

1996

• Valla, Svein; Brautaset, Trygve. (1996) Metabolsk ingeniørkunst; Hva er det og hva kan det brukes til?. Kjemi
  Vitenskapelig artikkel

1995

• Baptista, Antonio; Brautaset, Trygve; Drabløs, Finn; Martel, Paulo; Valla, Svein; Petersen, Steffen-B.. (1995) Electrostatic studies of carbohydrate active enzymes. Carbohydrate bioengineering : proceedings of an international conference
  Vitenskapelig artikkel

1994

• Brautaset, Trygve; Standal, Rune; Fjærvik, Espen; Valla, Svein. (1994) Nucleotide sequence and expression analysis of the Acetobacter xylinum phosphoglucomutase gene. Microbiology
  Vitenskapelig artikkel