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  1. Ansatte

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Duan Chen

Last ned pressefoto
Last ned pressefoto
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Duan Chen

Professor
Institutt for klinisk og molekylær medisin
Fakultet for medisin og helsevitenskap

duan.chen@ntnu.no
98409675 Gastrosenteret, 433.03.004 , Øya, Prinsesse Kristinas gate 1
Cristin Norwegian research database Full4Health Duan Chen
Om Publikasjoner Undervisning Formidling

Om

Prof. Duan Chen (Dr. Med.) er forskningsgruppeleder i forskningsgruppen for eksperimentell kirurgi ved Institutt for klinisk og molekylær medisin (IKOM) ved Fakultet for medisin og helsevitenskap, NTNU. Han ble uteksaminert fra Lunds universitet i Sverige, er professor ved NTNU og medlemm i Norges Tekniske Vitenskapsakademi og det Kongelige Norske Videnskabers Selskabs Akademi.  Han var president for gastrointestinal seksjon i International Union of Basic and Clinical Pharmacology (IUPHAR), og var leder for en arbeidspakke i EU-prosjektet “Understanding food-gut-brain mechanisms across the lifespan in the regulation of hunger and satiety for health” i det 7. europeiske rammeprogrammet. Han er medlem av styringsråd av International Regulatory Peptide Society (IRPS).

Vennligst se lenkene under for flere detaljer om hans forskning

http://www.ntnu.no/dmf/ikm/molbiol

http://www.ntnu.no/dmf/ikm/eksperimentell-kirurgi

http://www.ntnu.no/dmf/ikm/eksperimentell_pagaende-forskning

Kompetanseord

  • Endokronologi
  • Farmakologi
  • Fedme
  • Fedme og fedmekirurgi
  • Fordøyelsessykdommer
  • Gastroenterologisk kirurgi
  • Kirurgi
  • Kreftforskning
  • Mage
  • Molekylær cellebiologi
  • Peptider

Publikasjoner

  • Kronologisk
  • Etter kategori
  • Alle publikasjoner i Nasjonalt vitenarkiv (NVA)

2025

  • Corbo, Tarik; Graarud, Elisabeth Pimpisa; Resell, Mathilde Victoria; Kalajdzic, Abdurahim; Pojskic, Naris; Chen, Duan; Zhao, Chun Mei. (2025) Knowledge Discovery in Datasets: Druggable Targets for Pancreatic Ductal Adenocarcinoma. United European Gastroenterology Journal (UEG Journal)
    Konferanseabstract
  • Resell, Mathilde Victoria; Qvigstad, Gunnar; Wang, Timothy Cragin; Quante, Anne S.; González-Fernández, África; Gonzalez-Fernandez, Africa; Waldum, Helge; Chen, Duan; Zhao, Chun Mei. (2025) Translational studies on pancreatic cancer and gastric cancer: A methodology in PhD thesis. Frontiers in Pharmacology
    Fagartikkel
  • Resell, Mathilde Victoria; Rabben, Hanne-Line; Sharma, Animesh; Hagen, Lars; Hoang, Linh; Skogaker, Nan Elisabeth Tostrup; Aarvik, Anne; Bjåstad, Eirik Knudsen; Svensson, Magnus Kringstad; Amrutkar, Manoj. (2025) Proteomics profiling of research models for studying pancreatic ductal adenocarcinoma. Scientific Data
    Vitenskapelig artikkel
  • Zhi, Xiaofei; Wu, Feijing; Qian, Jin; Ochiai, Yosuke; Lian, Guodong; Malagola, Ermanno; Zheng, Biyun; Tu, Ruhong; Zeng, Yi; Kobayashi, Hiroki. (2025) Nociceptive neurons promote gastric tumour progression via a CGRP–RAMP1 axis. Nature
    Vitenskapelig artikkel
  • Resell, Mathilde Victoria; Graarud, Elisabeth Pimpisa; Rabben, Hanne-Line; Sharma, Animesh; Hagen, Lars; Hoang, Linh; Skogaker, Nan Elisabeth Tostrup; Aarvik, Anne; Svensson, Magnus Kringstad; Amrutkar, Manoj. (2025) Knowledge Discovery in Databases of Proteomics by Systems Modeling in Translational Research on Pancreatic Cancer. Proteomes
    Vitenskapelig artikkel

2024

  • Resell, Mathilde Victoria; Stranden, Morten; Qvigstad, Gunnar; Chen, Duan; Zhao, Chun Mei. (2024) Gaps between needs of patient and public involvement and interests of researchers on pancreatic cancer. Patient Education and Counseling
    Vitenskapelig artikkel
  • Zhao, Chun Mei; Rabben, Hanne-Line; Resell, Mathilde Victoria; Ianevski, Aleksandr; Sharma, Animesh; Hagen, Lars; Diez Sanchez, Alberto; Martin Alonso, Mara; Qvigstad, Gunnar; Kainov, Denis. (2024) INHIBITION OF EXOSOMES SUPPRESSES THE PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA: A STUDY USING MOUSE MODELS AND HUMAN ORGANOIDS. United European Gastroenterology Journal (UEG Journal)
    Fagartikkel
  • Andersen, Gøran Troseth; Ianevski, Aleksandr; Resell, Mathilde Victoria; Pojskic, Naris; Rabben, Hanne-Line; Geithus, Synne; Kodama, Yosuke; Tomita, Hiroyuki; Kainov, Denis; Grønbech, Jon Erik. (2024) Multi-bioinformatics revealed potential biomarkers and repurposed drugs for gastric adenocarcinoma-related gastric intestinal metaplasia. npj Systems Biology and Applications
    Vitenskapelig artikkel

2023

  • Andersen, Gøran Troseth; Zhao, Chun Mei; Grønbech, Jon Erik; Chen, Yijiang; Zayachkivska, Oksana; Røe, Oluf Dimitri; Chen, Duan. (2023) Clinical aspects in translational research on gastric tumorigenesis and development of new treatments*. Праці Наукового товариства імені Шевченка. Медичні науки
    Vitenskapelig oversiktsartikkel
  • Resell, Mathilde Victoria; Rabben, Hanne-Line; Amrutkar, Manoj; Hagen, Lars; Batra, Surinder K.; Verbeke, Caroline Sophie; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun Mei. (2023) Mo1138 COMPARATIVE PROTEOMICS REVEALS TRANSLATIONAL POTENTIAL OF TARGETS FOR PANCREATIC DUCTAL ADENOCARCINOMA. Gastroenterology
    Konferanseabstract
  • Andersen, Gøran Troseth; Lanevski, Aleksandr; Rabben, Hanne-Line; Geithus, Simon; Resell, Mathilde Victoria; Kodama, Yosuke; Tomita, Hiroyuki; Grønbech, Jon Erik; Wang, Timothy Cragin; Zhao, Chun Mei. (2023) GASTRIC INTESTINAL METAPLASIA VS. GASTRIC ADENOCARCINOMA OF PATIENTS: DISCTICT PHENOTYPIC TRAITS IN TRANSCRIPTOMICS. Gastroenterology
    Konferanseabstract
  • Zhao, Chun Mei; Rabben, Hanne-Line; Resell, Mathilde Victoria; Olsen, Magnus Kringstad; Cai, Xing; Zhang, Haiying; Batra, Surinder K.; Lyden, David C; Wang, Timothy Cragin; Chen, Duan. (2023) ARREST OF EXOCYTOSIS/ENDOCYTOSIS COUPLING INHIBITS PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA IN MICE. Gastroenterology
    Konferanseabstract
  • Andersen, Gøran Troseth; Chen, Duan; Grønbech, Jon Erik; Zhao, Chun Mei. (2023) Clinical Aspects in Translational Research on Gastric Tumorigenesis and Development of New Treatments. Norges teknisk-naturvitenskapelige universitet
    Doktoravhandling
  • Chen, Duan; Rehfeld, Jens Frederik; Watts, Alan G; Rorsman, Patrik; Gundlach, Andrew L.. (2023) History of key regulatory peptide systems and perspectives for future research. Journal of Neuroendocrinology (JNE)
    Vitenskapelig artikkel
  • Chen, Duan; Hagen, Susan J; Boyce, Malcolm; Zhao, Chun Mei. (2023) Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology. Journal of Neuroendocrinology (JNE)
    Vitenskapelig artikkel

2022

  • Brizozowski, Thomas; Sikiric, Predrag; Chen, Duan; Hahm, Ki-Baik; Seiwerth, Sven. (2022) Editorial: Protection and healing in the digestive system and other tissues: Novel factors, mechanisms, and pharmaceutical targets. Frontiers in Pharmacology
    Vitenskapelig artikkel

2021

  • Rabben, Hanne-Line; Andersen, Gøran Troseth; Ianevski, Aleksandr; Olsen, Magnus Kringstad; Kainov, Denis; Grønbech, Jon Erik; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei. (2021) Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer. Frontiers in Pharmacology
    Vitenskapelig artikkel
  • Rabben, Hanne-Line; Kodama, Yosuke; Nakamura, Masahiko; Bones, Atle M.; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei; Øverby, Anders. (2021) Chemopreventive Effects of Dietary Isothiocyanates in Animal Models of Gastric Cancer and Synergistic Anticancer Effects With Cisplatin in Human Gastric Cancer Cells. Frontiers in Pharmacology
    Vitenskapelig artikkel
  • Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan. (2021) Neural signaling modulates metabolism of gastric cancer. iScience
    Vitenskapelig artikkel

2020

  • Sheng, Weiwei; Ermanno, Malagola,; Henrik, Nienhüser; Zhengyu, Zhang; Woosook, Kim; Leah, Zamechek; Antonia, Sepulveda; Masahiro, Hata; Yoku, Hayakawa; Zhao, Chun-Mei. (2020) Hypergastrinemia Expands Gastric ECL Cells Through CCK2R Progenitor Cells via ERK Activation. Cellular and Molecular Gastroenterology and Hepatology (CMGH)
    Vitenskapelig artikkel
  • Eiden, Lee E.; Gundlach, Andrew L.; Grinevich, Valery; Lee, Mary R.; Mecawi, André S.; Chen, Duan; Buijs, Ruud M.; Hernández, Vito S.; Fajardo-Dolci, Germán; Zhang, Li-Mei. (2020) Regulatory peptides and systems biology: A new era of translational and reverse-translational neuroendocrinology. Journal of Neuroendocrinology (JNE)
    Vitenskapelig oversiktsartikkel

2019

  • Guida, Claudia; Stephen, Sam D.; Watson, Michael; Dempster, Niall; Larraufie, Pierre; Marjot, Thomas; Cargill, Tamsin; Rickers, Lisa; Pavlides, Michael; Tomlinson, Jeremy. (2019) PYY plays a key role in the resolution of diabetes following bariatric surgery in humans. EBioMedicine
    Vitenskapelig artikkel

2018

  • Zhao, Chun-Mei; Rabben, Hanne-Line; Zhu, Yanping; Olsen, Magnus Kringstad; Wang, Zhiqiang; Hao, Yanpeng; Cai, Xing; Fonseca, Davi de Miranda; Sharma, Animesh; Li, Mingna. (2018) 390 - A New Treatment for Pancreatic Cancer: Targeting Nervecancer Cell Crosstalk. Gastroenterology
    Konferanseabstract
  • Olsen, Magnus Kringstad; Johannessen, Helene; Ramracheya, Reshma; Zhao, Chun-Mei; Chen, Duan. (2018) New approaches for weight loss: Experiments using animal models. Current pharmaceutical design
    Vitenskapelig oversiktsartikkel
  • Guida, Claudia; McCulloch, Laura J.; Godazgar, Mahdieh; Stephen, Sam D.; Baker, Charlotte; Basco, Davide; Dong, Jiawen; Chen, Duan; Clark, Anne; Ramracheya, Reshma D.. (2018) Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY. Diabetes, obesity and metabolism
    Vitenskapelig artikkel
  • Chen, Duan; Ayala, Gustavo E. (2018) Innervating Prostate Cancer. New England Journal of Medicine
    Vitenskapelig artikkel

2017

  • Olsen, Magnus Kringstad; Choi, Man Hung; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2017) Time-restricted feeding on weekdays restricts weight gain: A study using rat models of high-fat diet-induced obesity. Physiology and Behavior
    Vitenskapelig artikkel
  • Hayakawa, Yoku; Sakitani, Kosuke; Konishi, Mitsuru; Asfaha, Samuel; Niikura, Ryota; Tomita, Hiroyuki; Renz, Bernhard W.; Tailor, Yagnesh; Macchini, Marina; Middelhoff, Moritz. (2017) Nerve growth factor promotes gastric tumorigenesis through aberrant cholinergic signaling. Cancer Cell
    Vitenskapelig artikkel

2016

  • Cai, Xing; Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Lundgren, Steinar; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2016) A Potential New Regimen (“Tricyclie”) for Treatment of Gastric Cancer: Targeting Glutamine-Dependent Wnt/β-Catenin-mTOR Signaling. Gastroenterology
    Konferanseabstract
  • Øverby, Anders; Rabben, Hanne-Line; Takahashi, Tetsufumi; Zhao, Chun Mei; Matsui, Hidenori; Nakamura, Masahiko; Chen, Duan. (2016) Possible mechanism-of-action of naturally occurring isothiocyanates in chemoprevention and adjuvant chemotherapy for gastric cancer. Gastroenterology
    Konferanseabstract
  • Rabben, Hanne-Line; Zhao, Chun-Mei; Hayakawa, Yoku; Wang, Timothy C.; Chen, Duan. (2016) Vagotomy and gastric tumorigenesis. Current Neuropharmacology
    Vitenskapelig oversiktsartikkel
  • Olsen, Magnus Kringstad; Johannessen, Helene; Cassie, Nikki; Barrett, Perry; Takeuchi, Koji; Kulseng, Bård Eirik; Chen, Duan; Zhao, Chun-Mei. (2016) Steady-state energy balance in animal models of obesity and weight loss. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel
  • Ramracheya, Reshma; McCulloch, Laura J.; Clark, Anne; Olsen, Magnus Kringstad; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) Roux-En-Y Gastric Bypass Surgery Restores Impaired Islet Architecture and Function in Type-2 Diabetes by Elevation of Plasma PYY. Gastroenterology
    Konferanseabstract
  • Chen, Duan; Olsen, Magnus Kringstad; Strømmen, Magnus; Johannessen, Helene; Bjøru, Hege Tevik; Salater, Sissel; Johnsen, Gjermund; Mårvik, Ronald; Zhao, Chun-Mei; Kulseng, Bård Eirik. (2016) Intragastric Injection of Botulinum Toxin a to Treat Obesity: Mechanism of Action and a Randomized, Double-Blind, Placebo-Controlled Phase II Trial With Open-Label Extension Study. Gastroenterology
    Konferanseabstract
  • Ramracheya, Reshma D.; McCulloch, Laura J.; Clark, Anne; Wiggins, David; Johannessen, Helene; Olsen, Magnus Kringstad; Cai, Xing; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery. Cell reports
    Vitenskapelig artikkel
  • Johannesen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens F.; Plasse, Geoffrey van der. (2016) Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action (OBES SURG, 10.1007/s11695-016-2278-x). Obesity Surgery
    Korrigendum
  • Dubeykovskaya, Z; Si, Y; Chen, X; Worthley, DL; Renz, BW; Urbanska, AM; Hayakawa, Y; Xu, T; Westphalen, CB; Dubeykovskiy, A. (2016) Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nature Communications
    Vitenskapelig artikkel
  • Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens; Plasse, Geoffrey van der. (2016) Vagal blocking for obesity control: a possible mechanism-of-action. Obesity Surgery
    Vitenskapelig artikkel

2015

  • Hayakawa, Yoku; Jin, Guangchun; Wang, Hongshan; Chen, Xiaowei; Westphalen, Christoph B.; Asfaha, Samuel; Renz, Bernhard W.; Ariyama, Hiroshi; Dubeykovskaya, Zinaida A.; Takemoto, Yoshihiro. (2015) CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis. Gut
    Vitenskapelig artikkel
  • Helander, Linda; Krokan, Hans Einar; Gederaas, Odrun Arna; Johnsson, Anders Carl G.; Chen, Duan. (2015) Hexylaminolevulinate Photodynamic Treatment of Cancer Cell Lines. PhD Thesis. Tapir Akademisk Forlag
    Doktoravhandling
  • Hayakawa, Yoku; Asfaha, Samuel; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor,, Yagnesh H.; Nagar,, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF Promotes Gastrointestinal Cancer Development Through Tumor-Associated Neurogenesis. Gastroenterology
    Konferanseabstract
  • Olsen, Magnus Kringstad; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2015) Comparison of different surgical procedures in animal models for a better consideration of personalized bariatric surgery. Gastroenterology
    Konferanseabstract
  • Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2015) 565Glutamine Metabolism As a Therapeutic Target for Gastric Cancer: Effects of Vagotomy Gastroenterology,Volume 148, Issue 4, Supplement 1, April 2015, Pages S-565–S-566. Gastroenterology
    Konferanseabstract
  • Boyce, Malcolm; Dowen, Sally; Turnbull, Gillian; Berg, Frans van den; Zhao, Chun-Mei; Chen, Duan; Black, James. (2015) Effect of netazepide, a gastrin/CCK2 receptor antagonist, on gastric acid secretion and rabeprazole-induced hypergastrinaemia in healthy subjectshypergastrinaemia in healthy subjects. British Journal of Clinical Pharmacology
    Vitenskapelig artikkel

2014

  • Oostindjer, Marije; Alexander, Jan; Amdam, Gro Vang; Andersen, Grethe; Bryan, Nathan S.; Chen, Duan; Corpet, Denis E.; Smet, Stefaan De; Dragsted, Lars Ove; Haug, Anna. (2014) The role of red and processed meat in colorectal cancer development: a perspective. Meat Science
    Vitenskapelig oversiktsartikkel
  • Øverby, Anders; Zhao, Chun-Mei; Wang, Timothy C.; Bones, Atle M.; Chen, Duan. (2014) Gastric cancer chemoprevention by phenethyl isothiocyanate-containing diet in chemically - but not genetically - induced gastric cancer in mice. Gastroenterology
    Konferanseabstract
  • Zhao, Chun-Mei; Myrvold, Helge Elliot; Chen, Duan. (2014) Reduced neurons in the ileum of proctocolectomized rat models. Medical Molecular Morphology
    Vitenskapelig artikkel
  • Øverby, Anders; Zhao, Chun-Mei; Chen, Duan. (2014) Plant phytochemicals: Potential anticancer agents against gastric cancer. Current opinion in pharmacology (Print)
    Vitenskapelig artikkel
  • Gudbrandsen, Oddrun Anita; Kodama, Yosuke; Mjøs, Svein Are; Zhao, Chun-Mei; Johannesen, Helene; Brattbakk, Hans-Richard; Haugen, Christine; Kulseng, Bård Eirik; Mellgren, Gunnar; Chen, Duan. (2014) Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats. Nutrition & Diabetes
    Vitenskapelig artikkel
  • Okabe, Susumu; Okamoto, Toshihiro; Zhao, Chun-Mei; Chen, Duan; Matsui, Hirofumi. (2014) Acetic acid induces cell death: An in vitro study using normal rat gastric mucosal cell line and rat and human gastric cancer and mesothelioma cell lines. Journal of Gastroenterology and Hepatology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Beisvag, Vidar; Kulseng, Bård Eirik; Sandvik, Arne Kristian; Rehfeld, Jens F.; Chen, Duan. (2014) Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Regulatory Peptides
    Vitenskapelig artikkel
  • Johannessen, Helene; Olsen, Magnus Kringstad; Cassie, Nikki; Barrett, Perry; Rehfeld, Jens F.; Holst, Jens J.; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2014) Preclinical Trial of Gastric Injection of Botulinum Toxin Type A as Weight-Loss-Surgery. Gastroenterology
    Konferanseabstract
  • Zhao, Chun-Mei; Yoku, Hayakawa; Westphalen,, Christoph B; Muthupalani,, Sureshkumar; Johannessen, Helene; Andersen, Gøran Troseth; Fox,, James G; Wang,, Timothy C.; Chen, Duan. (2014) Preclinical Trial of Botulinum Toxin Type a Injection in the Treatment of Gastric Cancer. Gastroenterology
    Konferanseabstract
  • Zhao, Chun-Mei; Mark, Kidd,; Chen, Duan. (2014) Triple Roles of Autophagy in Cytoprotection, Cell Death and Tumorigenesis With Special Reference to Gastric ECL Cells. Gastroenterology
    Konferanseabstract
  • Øverby, Anders; Zhao, Chun-Mei; Bones, Atle M.; Chen, Duan. (2014) Naturally occurring phenethyl isothiocyanate-induced inhibition of gastric cancer cell growth by disruption of microtubules. Journal of Gastroenterology and Hepatology
    Vitenskapelig artikkel
  • Dragsted, Lars Ove; Alexander, Jan; Amdam, Gro Vang; Bryan, Nathan S.; Chen, Duan; Haug, Anna; Karlsson, Anders H.; Kok, Theo M. de; Kulseng, Bård Eirik; Jr, Roy J. Martin. (2014) Letter to the Editor: Colorectal cancer risk and association with red meat - Is it inconsistent? Answer to the letter by Corpet, De Smet and Demeyer. Meat Science
    Kommentar
  • Zhao, Chun-Mei; Hayakawa, Yoku; Kodama, Yosuke; Muthupalani, Sureshkumar; Westphalen,, Christoph B.; Andersen, Gøran Troseth; Flatberg, Arnar; Johannessen, Helene; Friedman, Richard A.; Renz, Bernhard W.. (2014) Denervation suppresses gastric tumorigenesis. Science Translational Medicine
    Vitenskapelig artikkel

2013

  • Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård; Chen, Duan. (2013) Mechanistic Comparison between Gastric Bypass vs. Duodenal Switch with Sleeve Gastrectomy in Rat Models. PLOS ONE
    Vitenskapelig artikkel
  • Vigen, Alexander; Kodama, Yosuke; Viset, Trond; Fossmark, Reidar; Waldum, Helge; Kidd, Mark; Wang, Timothy C.; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2013) Immunohistochemical evidence for an impairment of autophagy in tumorigenesis of gastric carcinoids and adenocarcinomas in rodent models and patients. Histology and Histopathology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård; Chen, Duan. (2013) Galanin.
    Faglig kapittel
  • Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Lyle, Robert; Bettencourt, Paulo; Miroljub, Popovic; Witter, Menno; Barrett, Perry. (2013) Role of the vagus nerve in the gut-brain axis revealed by stimulation and blockade of the gastric vagus nerve. Gastroenterology
    Konferanseabstract
  • Chen, Duan; Zhao, Chun-Mei. (2013) Signaling pathways in control of gastric acid secretion and food-stomach-bone axis revealed by gene expression profiling in the stomach of genetically targeted mice deficient in CCK1 receptor and gastrin/CCK2 receptor. The FASEB Journal
    Konferanseabstract
  • Kodama, Yosuke; Zhao, Chun-Mei; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne; Beisvag, Vidar; Johannessen, Helene; Hayakawa, Yoku; Tomita, Hiroyuki. (2013) Denervation Suppresses Gastric Cancer Initiation and Progression Through Inhibition of the Cancer Niche. Gastroenterology
    Konferanseabstract

2012

  • Zhao, Chun-Mei; Chen, Duan. (2012) The ECL Cell: Relay Station for Gastric Integrity. Current Medicinal Chemistry
    Vitenskapelig oversiktsartikkel
  • Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Sousa, Mirta; Slupphaug, Geir; Kulseng, Bård Eirik; Chen, Duan. (2012) Eating Behavior and Glucagon-Like Peptide-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats Subjected to Ileal Interposition Associated with Sleeve Gastrectomy. Obesity Surgery
    Vitenskapelig artikkel
  • Erlandsen, Sten Even; Qvigstad, Gunnar; Fossmark, Reidar; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian. (2012) Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach. Regulatory Peptides
    Vitenskapelig artikkel
  • Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne Kristian; Fox, James G.; Kaneko, Kazuhiro; Wang, Timothy C.. (2012) Vagotomy Suppresses Gastric Cancer Progression in Mice. Gastroenterology
    Konferanseabstract
  • Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan. (2012) Gastric Bypass and Duodenal Switch Cause Body Weight Loss Through Different Mechanisms in Rats. Gastroenterology
    Konferanseabstract
  • Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan. (2012) Evidence for the Hindgut Hypothesis After Ileal Interposition Associated With Sleeve Gastrectomy: Increased Number of GLP-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats. Gastroenterology
    Konferanseabstract
  • Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan; Zhao, Chun-Mei. (2012) Food Intake Associated Gene Expression Profiles in the Stomach of Genetically Targeted Mice Deficient in CCK1 Receptor and/or CCK2 Receptor. Gastroenterology
    Konferanseabstract
  • Vigen, Alexander; Kodama, Yosuke; Viset, Trond; Fossmark, Reidar; Waldum, Helge; Kidd, Mark; Wang, Timothy C.; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2012) Impaired Autophagy in Gastric Carcinoids and Adenocarcinoma of Both Rodent Models and Patients. Gastroenterology
    Konferanseabstract
  • Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan; Revesz, David; Kuhn, Georg; Thorlin, Thorleif. (2012) Altered Eating Behavior by Subdiaphragmatic Truncal Vagus Nerve Stimulation in Rats. Gastroenterology
    Konferanseabstract
  • Chen, Duan; Zhao, Chun-Mei. (2012) Importance of Translational Research in GI Pharmacology: Lessons Learned from the Successes in History. Frontiers of gastrointestinal research
    Vitenskapelig artikkel
  • Okabe, Susumu; Kodama, Yosuke; Cao, HaiLong; Johannessen, Helene; Zhao, Chun-Mei; Wang, TC; Takahashi, Rei; Chen, Duan. (2012) Topical application of acetic acid in cytoreduction of gastric cancer model in mice. A technical report. Journal of Gastroenterology and Hepatology
    Vitenskapelig artikkel
  • Vigen, Reidar Alexander; Arum, Carl-Jørgen; Viset, Trond; Chen, Duan; Zhao, Chun-Mei. (2012) Experimental gastrocystoplasty in rats: Risk of developing ECLoma. Journal of Pediatric Urology
    Vitenskapelig artikkel
  • Vigen, Alexander; Kidd, Mark; Modlin, IM; Chen, Duan; Zhao, Chun-Mei. (2012) Ultrastructure of ECL cells in Mastomys after long-term treatment with H-2 receptor antagonist loxtidine. Medical Molecular Morphology
    Vitenskapelig artikkel
  • Liu, Yanhua; Zhu, Lijun; Pan, Ya; Sun, Lizhou; Chen, Duan; Li, Xiaonan. (2012) Adiponectin Levels in Circulation and Breast Milk and mRNA Expression in Adipose Tissue of Preeclampsia Women. Hypertension in Pregnancy
    Vitenskapelig artikkel
  • Vigen, Alexander; Chen, Duan; Zhao, Chun-Mei. (2012) Pathobiology of Gastric Carcinoids and Adenocarcinomas in Rodent Models and Patients: Studies of Gastrocystoplasty, Gender-Related Factors and Autophagy. Frontiers of gastrointestinal research
    Vitenskapelig artikkel

2011

  • Cui, Fei; Wang, Jian; Chen, Duan; Chen, Yi-Jiang. (2011) CD133 is a temporary marker of cancer stem cells in small cell lung cancer, but not in non-small cell lung cancer. Oncology Reports
    Vitenskapelig artikkel
  • Cao, HaiLong; Xue, L; Xu, X; Wu, Y; Zhu, J; Chen, L; Chen, Duan; Chen, YJ. (2011) Heat shock proteins in stabilization of spontaneously restored sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery. Cell stress & chaperones (Print)
    Vitenskapelig artikkel
  • Chen, D; Truong, T; Gaborieau, V; Byrnes, G; Chabrier, A; Chuang, SC; Olshan, AF; Weissler, MC; Luo, JC; Romkes, M. (2011) A Sex-Specific Association between a 15q25 Variant and Upper Aerodigestive Tract Cancers. Cancer Epidemiology, Biomarkers and Prevention
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Sandvik, Arne Kristian; Chen, Duan. (2011) Stomach-Bone Axis: Possible Involvement of Signaling Pathways and Vitamin D Governing Bone Metabolism. Gastroenterology
    Konferanseabstract
  • Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Kulseng, Bård Eirik; Chen, Duan. (2011) Energy Metabolism Following High-Fat Diet and Bariatric Surgeries (Gastric Bypass, Sleeve Gastrectomy, Duodenal Switch and Ileum Transposition) in Rats. Gastroenterology
    Konferanseabstract
  • Vigen, Reidar Alexander; Kidd, Mark; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2011) Ultrastructral Evidence for a Mechanism of ECL Cell Transformation to Gastric Carcinoid in Mastomys Involving Impairment of Autophagy and Loss of Gastrin Control. Gastroenterology
    Konferanseabstract
  • Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Sandvik, Arne Kristian; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2011) Evidence for Mechanism of Vagal Innervation in Gastric Cancer Initiation Involving Signaling Pathways Governing Stem Cells in Mice. Gastroenterology
    Konferanseabstract
  • Johannessen, Helene; Kodama, Yosuke; Cao, HaiLong; Kulseng, Baard; Zhao, Chun-Mei; Chen, Duan. (2011) Eating Behavior in Rats Subjected to Ileum Transposition and Sleeve Gastrectomy. Gastroenterology
    Konferanseabstract
  • Arum, Carl-Jørgen; Gederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Hjelde, Astrid; Krokan, Hans Einar; Svaasand, Lars O.; Chen, Duan; Zhao, Chun-Mei. (2011) Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action. Journal of Biomedical Optics
    Vitenskapelig artikkel
  • Vigen, Reidar Alexander; Chen, Duan; Syversen, Unni; Stunes, Astrid Kamilla; Håkanson, Rolf; Zhao, Chun-Mei. (2011) Serum gastrin and gastric enterochromaffin-like cells during estrous cycle, pregnancy and lactation, and in response to estrogen-like agents in rats. Journal of Physiology and Pharmacology
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei. (2011) The possible existence of a gut-bone axis suggested by studies of genetically manipulated mouse models?. Current pharmaceutical design
    Vitenskapelig oversiktsartikkel
  • Cao, HaiLong; Xue, L; Xu, X; Wu, Y; Zhu, J; Chen, L; Chen, Duan; Chen, YJ. (2011) Heat shock proteins in stabilization of spontaneously restorted sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery. Cell stress & chaperones (Print)
    Vitenskapelig artikkel
  • Salome, N; Taube, M; Egecioglu, E; Hansson, C; Karlsson, Bjørn; Chen, Duan; Andersson, DR; Georg-Kuhn, H; Ohlsson, C; Dickson, SL. (2011) Gastrectomy alters emotional reactivity in rats: neurobiological mechanisms. European Journal of Neuroscience
    Vitenskapelig artikkel
  • Hutchinson, Lloyd; Stenström, Björn; Chen, Duan; Piperdi, Bilal; Levey, Sara; Lyle, Stephen; Wang, Timothy C.; Houghton, J. (2011) Human Barrett's adenocarcinoma of the esophagus, associated myofibroblasts, and endothelium can arise from bone marrow-derived cells after allogeneic stem cell transplant. Stem Cells and Development
    Vitenskapelig artikkel

2010

  • Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) Gene Expression Profiling and Pathway Analysis of Superficial Bladder Cancer in Rats. Urology
    Vitenskapelig artikkel
  • Arum, Carl-Jørgen; Anderssen, Endre; Viset, Trond; Kodama, Yosuke; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) Cancer Immunoediting from Immunosurveillance to Tumor Escape in Microvillus-Formed Niche: A Study of Syngeneic Orthotopic Rat Bladder Cancer Model in Comparison with Human Bladder Cancer. Neoplasia
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei. (2010) Complexity of Gastric Acid Secretion Revealed by Targeted Gene Disruption in Mice. Current pharmaceutical design
    Vitenskapelig oversiktsartikkel
  • Arum, Carl-Jørgen; Kodama, Yosuke; Rolim, Natale Pinheiro Lage; Widerøe, Marius; Anderssen, Endre; Viset, Trond; Otterlei, Marit; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World Journal of Urology
    Vitenskapelig artikkel
  • Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Bård Eirik; Chen, Duan. (2010) Eating Behavior in Rats Subjected to Vagotomy, Sleeve Gastrectomy, and Duodenal Switch. Journal of Gastrointestinal Surgery
    Vitenskapelig artikkel
  • Zheng, Liang; Xu, Jing; Qiu, Wanshan; Liu, Xiang; Zhao, Chun-Mei; Chen, Duan; Chen, Yi-Jiang. (2010) CARDIOPROTECTION OF EXOGENOUS ERYTHROPOIETIN IN MICE WITH LIGATURE-INDUCED AORTIC STENOSIS: EFFECTS ON MALADAPTIVE CARDIAC HYPERTROPHY. Journal of Physiology and Pharmacology
    Vitenskapelig artikkel
  • Song, Zhigang; Bhagat, Govind; Quante, Michael; Baik, Gwang Ho; Marrache, Frederic; Tu, Shuiping; Zhao, Chun-Mei; Chen, Duan; Dannenberg, Andrew; Wang, Timothy C.. (2010) Potential carcinogenic effects of cigarette smoke and Swedish moist snuff on pancreas: a study using a transgenic mouse model of chronic pancreatitis. Laboratory Investigation
    Vitenskapelig artikkel
  • Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Baad; Chen, Duan. (2010) Eating Behavior in Rats Subject to Vagotomy, Sleeve Gastrectomy and Duodenal Switch. Gastroenterology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan. (2010) Gastric ECL cells, rather than gastric acid, play an important role in gut-bone axis. Gastroenterology
    Konferanseabstract
  • Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2010) Truncal vagotomy inhibited gastric cancer initiation in the INS-GAS mouse model. Gastroenterology
    Konferanseabstract
  • Westerberg, I.; Walther, A; Guerrero, J-L; Coello, Z; Halldin, S; Xu, Chong-Yu; Chen, D; Lundin, L-C. (2010) Precipitation data in a mountainous catchment in Honduras: quality assessment and spatiotemporal characteristics. Theoretical and Applied Climatology
    Vitenskapelig artikkel

2009

  • Furnes, Marianne Waldum; Zhao, Chun-Mei; Chen, Duan. (2009) Development of Obesity is Associated with Increased Calories per Meal Rather than per Day. A Study of High-Fat Diet-Induced Obesity in Young Rats. Obesity Surgery
    Vitenskapelig artikkel
  • Furnes, Marianne; Zhao, Chun-Mei; Stenstrøm, Bjørn; Arum, Carl-Jørgen; Tømmerås, Karin; Kulseng, Bård Eirik; Chen, Duan. (2009) Feeding behavior and body weight development: Lessons from rats subjected to gastric bypass surgery or high-fat diet. Journal of Physiology and Pharmacology
    Vitenskapelig artikkel
  • Chen, Duan; Furnes, Marianne Waldum; Zhao, Chun-Mei. (2009) Translational research on obesity: from bedside to bench. Journal of Physiology and Pharmacology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Kodama, Yosuke; Sandvik, Arne Kristian; Chen, Duan. (2009) Differentiation of Gastric ECL Cells in CCK 1+2 Receptor Double Knockout Mice. Gastroenterology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Anderssen, Endre; Chen, Duan. (2009) Gene Expression and Pathway Analysis of Mouse Stomach: Gastric ECL Cells May Produce Vitamin D. Gastroenterology
    Vitenskapelig artikkel
  • Song, Zhigang; Bhagat, Govind; Baik, Gwang Ho; Gordon, Shanisha A.; Mitchell, Anthony; Zhao, Chun-Mei; Chen, Duan; Dannenberg,, Andrew; Wang, Timothy C.. (2009) Development of a Mouse Model of Inflammation-Dependent Pancreatic Cancer. Gastroenterology
    Vitenskapelig artikkel
  • Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2009) Gene expression profiles of bladder cancer: Comparison between orthotopic rat bladder cancer model and human bladder cancer patients. European Urology. Supplement
    Konferanseabstract

2008

  • Egecioglu, E; Stenstrom, B; Pinnock, SB; Tung, LYC; Cour, CD de la; Lindqvist, A; Hakanson, R; Syversen, Unni; Chen, Duan; Dickson, SL. (2008) Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents. Regulatory Peptides
    Vitenskapelig artikkel
  • Furnes, Marianne Waldum; Tømmerås, Karin; Arum, Carl-Jørgen; Zhao, Chun-Mei; Chen, Duan. (2008) Gastric bypass surgery causes body weight loss without reducing food intake in rats. Obesity Surgery
    Vitenskapelig artikkel
  • Bernsand, Maria; Zhao, Chun-Mei; Chen, Duan; Håkanson, R; Stenstrøm, Bjørn; Norlén, Per. (2008) Ischemia mobilizes histamine but not pancreastatin from ECL cells of rat stomach: evidence for a cytosolic histamine compartment. Cell and Tissue Research
    Vitenskapelig artikkel
  • Furnes, Marianne Waldum; Stenstrøm, Bjørn; Tømmerås, Karin; Skoglund, Trine; Dickson, SL; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2008) Feeding behaviour in rats subjected to gastrectomy or gastric bypass surgery. European Surgical Research
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Martinez, V; Piqueras, L; Wang, L-X; Taché, Y; Chen, Duan. (2008) Control of gastric acid secretion in somatostatin receptor 2 deficient mice: shift from endocrine/paracrine to neurocrine pathways. Endocrinology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Furnes, Marianne Waldum; Stenström, Björn; Kulseng, Bård Eirik; Chen, Duan. (2008) Characterization of obestatin- and ghrelin-producing cells in the gastrointestinal tract and pancreas of rats: an immunohistochemical and electron-microscopic study. Cell and Tissue Research
    Vitenskapelig artikkel
  • Furnes, Marianne Waldum; Chen, Duan. (2008) Feeding behaviour and body weight developement: lessons from rats. Tapir Akademisk Forlag
    Doktoravhandling
  • Chen, Duan. (2008) Feeding Behavior and Body Weight Development: Lessons from rats. NTNU
    Doktoravhandling
  • Qiu, Wanshan; Zheng, Liang; Gu, Haiyong; Chen, Duan; Chen, Yijiang. (2008) Comparison between adult and infant lung injury in a rabbit ischemia-reperfusion model. Journal of Thoracic and Cardiovascular Surgery
    Vitenskapelig artikkel
  • Qiu, Wanshan; Gu, Haiyong; Zheng, Liang; Zhou, Jianwei; Chen, Duan; Chen, Yijiang. (2008) Pretreatment with edaravone reduces lung mitochondrial damage in an infant rabbit ischemia-reperfusion model. Journal of Pediatric Surgery
    Vitenskapelig artikkel
  • Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Hjelde, Astrid; Zhao, Chun-Mei; Chen, Duan; Krokan, Hans Einar; Svaasand, Lars O.. (2008) Monitoring of Hexyl 5-aminolevulinate Induced Photodynamic Therapy in Rat Bladder Cancer by Optical Spectroscopy. Journal of Biomedical Optics
    Vitenskapelig artikkel

2007

  • Chen, Duan; Karlsson, Bjørn; Zhao, Chun-Mei; Wadstrom, T. (2007) Does Helicobacter pylori infection per se cause gastric cancer or duodenal ulcer? Inadequate evidence in Mongolian gerbils and inbred mice. FEMS Immunology and Medical Microbiology
    Vitenskapelig artikkel
  • Karlsson, Bjørn; Zhao, Chun-Mei; Rogers, AB; Nilsson, HO; Sturegard, E; Lundgren, Steinar; Fox, J; Wang, Timothy C.; Chen, Duan; Wadstrom, T. (2007) Swedish moist snuff accelerates gastric cancer development in Helicobacter pylori-infected wild-type and gastrin transgenic mice. Carcinogenesis
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei. (2007) Genetically engineered mice: a new paradigm to study gastric physiology. Current Opinion in Gastroenterology
    Vitenskapelig artikkel
  • Arum, Carl-Jørgen; Tømmerås, Karin; Anderssen, Endre; Zhao, Chun-Mei; Chen, Duan. (2007) Gene expression profiling and pathway analysis of orthotopic rat bladder cancer model. European Urology. Supplement
    Konferanseabstract
  • Zhao, Chun-Mei; Chen, Duan. (2007) Genetically engineered mice: a new paradigm to study gastric physiology. Stomach and duodenum. Current Opinion in Gastroenterology
    Vitenskapelig artikkel
  • Egecioglu, E; Karlsson, Bjørn; Pinnock, S B; Tung, LYC; Cour, C Dornonville de la; Lindqvist, A; Håkanson, R; Syversen, Unni; Chen, Duan; Dickson, SL. (2007) Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents. Regulatory Peptides
    Vitenskapelig artikkel

2006

  • Zhao, Chun-Mei; Chen, Duan; Stenström, Björn. (2006) Does Helicobacter pylori infection per se cause gastric cancer and/or duodenal ulcer in Mongolian gerbils and wild-type mice? A critical micro-review. FEMS Immunology and Medical Microbiology
    Vitenskapelig artikkel
  • Stenstrøm, Bjørn; Furnes, Marianne Waldum; Tømmerås, Karin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan. (2006) Mechanism of gastric bypass-induced body weight loss: One-year follow-up after micro-gastric bypass in rats. Journal of Gastrointestinal Surgery
    Vitenskapelig artikkel
  • Chen, Duan; Aihara, Takeshi; Zhao, Chun-Mei; Håkanson, Rolf; Okabe, Susumu. (2006) Differentiation of the Gastric Mucosa I. Role of histamine in control of function and integrity of oxyntic mucosa: understanding gastric physiology through disruption of targeted genes. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel
  • Stenstrøm, Bjørn Olof; Zhao, Chun-Mei; Tømmerås, Karin; Arum, Carl-Jørgen; Chen, Duan. (2006) Is gastrin partially responsible for body weight reduction after gastric bypass?. European Surgical Research
    Vitenskapelig artikkel
  • Vigen, RA; Arum, Carl-Jørgen; Karlsson, Bjørn; Chen, Duan. (2006) A unique surgical model for studying the physiology of gastrin: Gastrocystoplasty and fundectomy. Scandinavian Journal of Laboratory Animal Science
    Vitenskapelig artikkel
  • Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Krokan, Hans Einar; Chen, Duan; Hjelme, Dag Roar; Svaasand, Lars O.. (2006) Monitoring of hALA induced PDT in rat bladder cancer by optical spectroscopy. Lasers in Surgery and Medicine
    Konferanseabstract
  • Fykse, Vidar; Solligård, Erik; Bendheim, Marianne Østensen; Chen, Duan; Grønbech, Jon Erik; Sandvik, Arne Kristian; Waldum, Helge. (2006) ECL cell histamine mobilization and parietal cell stimulation in the rat stomach studied by microdialysis and electron microscopy. Acta Physiologica
    Vitenskapelig artikkel

2005

  • Chen, Duan; Friis-Hansen, L; Håkanson, R; Zhao, Chun-Mei. (2005) Genetic dissection of the signaling pathways that control gastric acid secretion. InflammoPharmacology
    Vitenskapelig oversiktsartikkel
  • Zhao, Chun-Mei; Håkanson, Rolf; Chen, Duan. (2005) Secretory organelles in ECL cells: effects of pharmacological blockade of the gastrin/CCK2 receptor versus its elimination by gene targeting. InflammoPharmacology
    Vitenskapelig oversiktsartikkel
  • Zhao, Chun-Mei; Fossmark, Reidar; Martinsen, Tom Christian; Kawase, Shiro; Chen, Duan; Waldum, Helge. (2005) Dedifferentiation of enterochromaffin-like cells in gastric cancer of hypergastrinemic cotton rats. APMIS - Journal of Pathologiy, Microbiology and Immunology
    Vitenskapelig artikkel
  • Stenstrøm, Bjørn; Løseth, Kirsti; Bevanger, Lars Solbu; Sturegård, E; Wadstrøm, T; Chen, Duan. (2005) Gastric bypass surgery does not increase susceptibility to Helicobacter pylori infection in the stomach of rat or mouse. InflammoPharmacology
    Vitenskapelig artikkel
  • Arum, Carl-Jørgen; Vigen, RA; Karlsson, Bjørn; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2005) Acid secretion in urinary bladder of rats subjected to gastrocystoplasty. InflammoPharmacology
    Vitenskapelig artikkel
  • Fossmark, Reidar; Zhao, Chun-Mei; Martinsen, Tom Christian; Kawase, Shiro; Chen, Duan; Waldum, Helge. (2005) Dedifferentiation of enterochromaffin-like cells in gastric cancer of cotton rats. APMIS - Journal of Pathologiy, Microbiology and Immunology
    Vitenskapelig artikkel
  • Martinsen, Tom Christian; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian; Zahlsen, Kolbjørn; Aamo, T.; Waldum, Helge. (2005) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alfa. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel

2004

  • Chen, Duan. (2004) ECL cells in a physiological context.
    Vitenskapelig kapittel
  • Chen, Duan. (2004) Absence of the cholecystokinin2 receptor alters the structure and function of gastric parietal and ECL cells.
    Vitenskapelig kapittel
  • Chen, Duan; Zhao, Chun-Mei; Hakanson, R; Samuelson, LC; Rehfeld, JF; Friis-Hansen, L. (2004) Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Gastroenterology
    Vitenskapelig artikkel
  • Cui, GL; Koh, TJ; Chen, Duan; Zhao, Chun-Mei; Takaishi, S; Dockray, GJ; Varro, A; Rogers, AB; Fox, JG; Wang, T. (2004) Overexpression of glycine-extended gastrin inhibits parietal cell loss and atrophy in the mouse stomach. Cancer Research
    Vitenskapelig artikkel
  • Rydning, Astrid; Bakkelund, Karin Elvenes; Chen, Duan; Falkmer, Sture Emil; Grønbech, Jon Erik. (2004) Role of bradykinin on gastric vasodilation caused by hypertonic saline and acid back diffusion. Regulatory Peptides
    Vitenskapelig artikkel
  • Chen, Duan. (2004) ECL cells. Encyclopedia of Endocrinology and Endocrine Diseases
    Vitenskapelig artikkel

2003

  • Zhao, Chun-Mei; Chen, D; Yamada, H.; delaCour, C. Dornonville; Lindström, E.; Persson, L.; Håkanson, R. (2003) Rat stomach ECL cells: mode of activation of histidine decarboxylase. Regulatory Peptides
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Chen, D; Yamada, H.; delaCour, C. Dornonville; Lindström, E.; Persson, L.; Håkanson, R. (2003) Rat stomach ECL cells: mode of activation of histidine decarboxylase. Regulatory Peptides
    Vitenskapelig artikkel
  • Kopin, Alan S.; McBride, E.W.; Chen, Ci; Chen, Duan; Zhao, Chun-Mei; Beinborn, M. (2003) Identification of a series of CCK-2 receptor nonpeptide agonists: Sensitivity to stereochemistry and a receptor point mutation. PNAS
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Chen, Duan; Håkanson, Rolf. (2003) Rat stomach ECL cells: mode of activation of histidine decaroxylase. Regulatory Peptides
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Wang, X; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T; Chen, Duan. (2003) Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastrin-deficient mice. Regulatory Peptides
    Vitenskapelig artikkel
  • Waldum, Camilla; Zhao, Chun-Mei; Waldum, Helge; Halgunset, Jostein; Chen, Duan. (2003) Cheese-induced body weight gain is not accompanied by an increase of gastric cells producing leptin, gastrin, or pancreastatin in mice. Scandinavian Journal of Laboratory Animal Science
    Vitenskapelig artikkel
  • Aihara, T.; Fujishita, T.; Kanatani, K.; Furutani, K.; Nakamura, E.; Taketo, M.M.; Matsui, M.; Chen, Duan; Okabe, S.. (2003) Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor-knockout mice. Gastroenterology
    Vitenskapelig artikkel
  • Waldum, C.; Zhao, C.M.; Waldum, Helge; Halgunset, Jostein; Chen, Duan. (2003) Cheese-induced body weight is not accompained by an increase of gastric cells producing leptin, ghrelin, gastrin, or pancreastatin in mice. Scandinavian Journal of Laboratory Animal Science
    Vitenskapelig artikkel
  • Kopin, Alan S.; McBride, E.W.; Ren, Y.; Chen, Duan; Zhao, C.M.. (2003) Identification of a series of CCK-2 receptor nonpeptide agonists: sensitivity to stereochemistry and a receptor point mutation. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
    Vitenskapelig artikkel
  • Cui, G; Koh, T.; Chen, Duan; Zhao, C.M.; Dockery, J.; Varro, A; Fox, J; Wang, T. (2003) Overexpression of glycine-extended gastrin maintains acid secretion and prevents the development of preneoplasia in the stomach via reducing parietal cell lost in transgenic mice. Gastroenterology
    Vitenskapelig artikkel
  • Zhao, C-M; Wang, X.; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T; Chen, Duan. (2003) Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastroindeficient mice. Regulatory Peptides
    Vitenskapelig artikkel
  • Chen, Duan; Håkanson, R. (2003) Mechanism of gastric ECL-cell tumor induction: Observations in the rat. WHO IARC Technical Publication
    Vitenskapelig artikkel
  • Martinsen, Tom Christian; Bakke, I; Chen, Duan; Aamo, T; Zahlsen, Kolbjørn; Waldum, Helge. (2003) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPARa receptors. Gastroenterology
    Vitenskapelig artikkel

2002

  • Chen, Duan; Zhao, Chun-Mei; Wisam, Al-Haider; Håkanson, Rolf; Rehfeld, Jens F.; Kopin, Alan S.. (2002) Differentiation of Gastric ECL Cells is Altered in CCK2 Receptor-Deficient Mice. Gastroenterology
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei; Håkanson, Rolf; Rehfeld, Jens F.. (2002) Gastric Phenotypic Abnormality in Cholecystokinin 2 Receptor Null Mice. Pharmacology and Toxicology
    Vitenskapelig artikkel
  • Chen, Duan; Wallengren, Joanna. (2002) Local skin lesions in the rat after subcutaneous deposition of Capsaicin. Skin pharmacology and applied skin physiology
    Vitenskapelig artikkel
  • Farrell, James J.; Taupin, Douglas; Koh, Theodore J.; Chen, Duan; Zhao, Chun-Mei; Podolsky, Daniel K.; Wang, Timothy C.. (2002) TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. The Journal of Clinical Investigation
    Vitenskapelig artikkel
  • Lehto-Axtelius, D.; Chen, Duan; Surve, V.V.; Håkanson, Rolf. (2002) Post-Gatrectomy Osteopenia in the Rat. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel
  • Chen, Duan; Håkanson, Rolf; Rehfeld, Jens F.; Zhao, Chun-Mei. (2002) CCK2 receptors are necessary for the differentiation and proliferation of ECL cells in mouse and rat stomach. Immunopharmacology
    Vitenskapelig artikkel

2001

  • Björkqvist, Maria; Norlén, Per; Kitano, Masayuki; Chen, Duan; Zhao, Chun-Mei; delaCour, D Dornonville; Gagnemo-Persson, Rebecca; Håkanson, Rolf. (2001) Effects of CCK-2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats. Pharmacology and Toxicology
    Vitenskapelig artikkel
  • Nieuwenhove, Yves van; Chen, Duan; Willems, Gerard. (2001) Postprandial cell proliferation in the esophageal epithelium of rats. Regulatory Peptides
    Vitenskapelig artikkel
  • delaCour, D Dornonville; Björkqvist, Maria; Sandvik, Arne Kristian; Håkanson, Rolf; Chen, D. (2001) A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control. Regulatory Peptides
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Bakke, Ingunn; Tostrup-Skogaker, Nan; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research
    Vitenskapelig artikkel
  • Cui, Guanglin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Long-term omeprazole treatment suppress body weight gain and bone mineralization in young male rats. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel
  • Håkanson, Rolf; Chen, Duan; Lindström, Erik; Bernsand, Maria; Norlén, Per. (2001) Control of secretion from rat stomach ECL cells in situ and in primary culture. Scandinavian Journal of Clinical and Laboratory Investigation
    Vitenskapelig artikkel
  • Lindström, Erik; Chen, Duan; Norlén, Per; Andersson, Kjell; Håkanson, Rolf. (2001) Control of gastric acid secretion: the gastrin-ECL cell - parietal cell axis. Comparative Biochemistry and Physiology A
    Vitenskapelig artikkel
  • Waldum, Camilla; Zhao, Chun-Mei; Chen, Duan. (2001) Are current textbooks good enough for physiology education? For example, the ECL-cells are missing. Advances in Physiology Education
    Vitenskapelig artikkel
  • Cui, G.-L.; Syversen, Unni; Chao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Long-term Omeprazole treatment Suppresses Body Weight Gain and Bone Mineralization in Young Male Rats. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei; Falkmer, Sture Emil; Waldum, Helge; Syder, Andrew; Gordon, Jeffrey. (2001) Ablation of Parietal Cells Is Associated with ECL-cell Hyperplasia in Transgenic Mice with a Genetically Engineered Ablation of Their Parietal Cell Lineage. Gastroenterology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Bakke, Ingunn; Skogaker, Nan Elisabeth Tostrup; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research
    Vitenskapelig artikkel

2000

  • Syversen, Unni; Waldum, HL; Slørdahl, K; Chen, D. (2000) Synergistic effects of the pesticides toxaphene and dieldrin on bone mineral density in female rats. Journal of Bone and Mineral Research
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, CM; Dockray, GJ; Varro, A; Hoek, AV; Sinclair, NF; Wang, TC; Koh, TJ. (2000) Glycine-Extended Gastrin Synergizes With Gastrin 17 to Stimulate Acid Secretion in Gastrin-Deficient Mice. Gastroenterology
    Vitenskapelig artikkel
  • Norlèn, P; Lindström, E; Zhao, CM; Kitano, M; Chen, D; Andersson, K; Håkanson, R. (2000) x-Fluromethylhistidine depletes histamine from secreting but not from non-secreting rat stomach ECL cells. European Journal of Pharmacology: Environmental Toxicology and Pharmacology
    Vitenskapelig artikkel
  • Wang, TC; Dangler, CA; Chen, D; Goldenring, JR; Koh, T; Raychowdhury, R; Coffey, RJ; Ito, S; Varro, A; Dockray, GJ. (2000) Synergistic Interaction Between Hypergastrinemia and Helicobacter Infection in a Mouse Model of Gastric Cancer. Gastroenterology
    Vitenskapelig artikkel
  • Chen, D; Zhao, CM; Norlen, P; Björkqvist, M; Ding, XQ; Kitano, M; Hakanson, R. (2000) Effect of cholecystokinin-2 receptor blockade on rat stomach ECL cells. A histochemical, electron-microscopic and chemical study. Cell and Tissue Research
    Vitenskapelig artikkel
  • Norlen, P.; Lindstrøm, E.; Zhao, Chun-Mei; Kitano, M.; Chen, Duan; Andersson, K.; Håkansson, R.. (2000) alpha-fluoromethylhistidine depletes histamine from secreting but not from non-secreting rat stomach ECL-cells. European Journal of Clinical Pharmacology
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei; Dockray, Graham J.; Varro, Andrea; Hoek, Alfred van; Sinclair, Natalie F.; Wang, Timothy C.. (2000) Glycine-Extended Gastrin Synergizes With Gastrin 17 to Stimulate Acid Secretion in Gastrin-Deficient Mice. Gastroenterology
    Vitenskapelig artikkel

Tidsskriftspublikasjoner

  • Corbo, Tarik; Graarud, Elisabeth Pimpisa; Resell, Mathilde Victoria; Kalajdzic, Abdurahim; Pojskic, Naris; Chen, Duan; Zhao, Chun Mei. (2025) Knowledge Discovery in Datasets: Druggable Targets for Pancreatic Ductal Adenocarcinoma. United European Gastroenterology Journal (UEG Journal)
    Konferanseabstract
  • Rabben, Hanne-Line; Andersen, Gøran Troseth; Ianevski, Aleksandr; Olsen, Magnus Kringstad; Kainov, Denis; Grønbech, Jon Erik; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei. (2021) Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer. Frontiers in Pharmacology
    Vitenskapelig artikkel
  • Furnes, Marianne Waldum; Zhao, Chun-Mei; Chen, Duan. (2009) Development of Obesity is Associated with Increased Calories per Meal Rather than per Day. A Study of High-Fat Diet-Induced Obesity in Young Rats. Obesity Surgery
    Vitenskapelig artikkel
  • Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) Gene Expression Profiling and Pathway Analysis of Superficial Bladder Cancer in Rats. Urology
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei; Wisam, Al-Haider; Håkanson, Rolf; Rehfeld, Jens F.; Kopin, Alan S.. (2002) Differentiation of Gastric ECL Cells is Altered in CCK2 Receptor-Deficient Mice. Gastroenterology
    Vitenskapelig artikkel
  • Cui, Fei; Wang, Jian; Chen, Duan; Chen, Yi-Jiang. (2011) CD133 is a temporary marker of cancer stem cells in small cell lung cancer, but not in non-small cell lung cancer. Oncology Reports
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei; Håkanson, Rolf; Rehfeld, Jens F.. (2002) Gastric Phenotypic Abnormality in Cholecystokinin 2 Receptor Null Mice. Pharmacology and Toxicology
    Vitenskapelig artikkel
  • Rabben, Hanne-Line; Kodama, Yosuke; Nakamura, Masahiko; Bones, Atle M.; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei; Øverby, Anders. (2021) Chemopreventive Effects of Dietary Isothiocyanates in Animal Models of Gastric Cancer and Synergistic Anticancer Effects With Cisplatin in Human Gastric Cancer Cells. Frontiers in Pharmacology
    Vitenskapelig artikkel
  • Resell, Mathilde Victoria; Qvigstad, Gunnar; Wang, Timothy Cragin; Quante, Anne S.; González-Fernández, África; Gonzalez-Fernandez, Africa; Waldum, Helge; Chen, Duan; Zhao, Chun Mei. (2025) Translational studies on pancreatic cancer and gastric cancer: A methodology in PhD thesis. Frontiers in Pharmacology
    Fagartikkel
  • Chen, Duan; Wallengren, Joanna. (2002) Local skin lesions in the rat after subcutaneous deposition of Capsaicin. Skin pharmacology and applied skin physiology
    Vitenskapelig artikkel
  • Farrell, James J.; Taupin, Douglas; Koh, Theodore J.; Chen, Duan; Zhao, Chun-Mei; Podolsky, Daniel K.; Wang, Timothy C.. (2002) TFF2/SP-deficient mice show decreased gastric proliferation, increased acid secretion, and increased susceptibility to NSAID injury. The Journal of Clinical Investigation
    Vitenskapelig artikkel
  • Lehto-Axtelius, D.; Chen, Duan; Surve, V.V.; Håkanson, Rolf. (2002) Post-Gatrectomy Osteopenia in the Rat. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Rabben, Hanne-Line; Zhu, Yanping; Olsen, Magnus Kringstad; Wang, Zhiqiang; Hao, Yanpeng; Cai, Xing; Fonseca, Davi de Miranda; Sharma, Animesh; Li, Mingna. (2018) 390 - A New Treatment for Pancreatic Cancer: Targeting Nervecancer Cell Crosstalk. Gastroenterology
    Konferanseabstract
  • Olsen, Magnus Kringstad; Choi, Man Hung; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2017) Time-restricted feeding on weekdays restricts weight gain: A study using rat models of high-fat diet-induced obesity. Physiology and Behavior
    Vitenskapelig artikkel
  • Syversen, Unni; Waldum, HL; Slørdahl, K; Chen, D. (2000) Synergistic effects of the pesticides toxaphene and dieldrin on bone mineral density in female rats. Journal of Bone and Mineral Research
    Vitenskapelig artikkel
  • Arum, Carl-Jørgen; Anderssen, Endre; Viset, Trond; Kodama, Yosuke; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) Cancer Immunoediting from Immunosurveillance to Tumor Escape in Microvillus-Formed Niche: A Study of Syngeneic Orthotopic Rat Bladder Cancer Model in Comparison with Human Bladder Cancer. Neoplasia
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, CM; Dockray, GJ; Varro, A; Hoek, AV; Sinclair, NF; Wang, TC; Koh, TJ. (2000) Glycine-Extended Gastrin Synergizes With Gastrin 17 to Stimulate Acid Secretion in Gastrin-Deficient Mice. Gastroenterology
    Vitenskapelig artikkel
  • Norlèn, P; Lindström, E; Zhao, CM; Kitano, M; Chen, D; Andersson, K; Håkanson, R. (2000) x-Fluromethylhistidine depletes histamine from secreting but not from non-secreting rat stomach ECL cells. European Journal of Pharmacology: Environmental Toxicology and Pharmacology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Chen, Duan; Stenström, Björn. (2006) Does Helicobacter pylori infection per se cause gastric cancer and/or duodenal ulcer in Mongolian gerbils and wild-type mice? A critical micro-review. FEMS Immunology and Medical Microbiology
    Vitenskapelig artikkel
  • Stenstrøm, Bjørn; Furnes, Marianne Waldum; Tømmerås, Karin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan. (2006) Mechanism of gastric bypass-induced body weight loss: One-year follow-up after micro-gastric bypass in rats. Journal of Gastrointestinal Surgery
    Vitenskapelig artikkel
  • Chen, Duan; Aihara, Takeshi; Zhao, Chun-Mei; Håkanson, Rolf; Okabe, Susumu. (2006) Differentiation of the Gastric Mucosa I. Role of histamine in control of function and integrity of oxyntic mucosa: understanding gastric physiology through disruption of targeted genes. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel
  • Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård; Chen, Duan. (2013) Mechanistic Comparison between Gastric Bypass vs. Duodenal Switch with Sleeve Gastrectomy in Rat Models. PLOS ONE
    Vitenskapelig artikkel
  • Andersen, Gøran Troseth; Zhao, Chun Mei; Grønbech, Jon Erik; Chen, Yijiang; Zayachkivska, Oksana; Røe, Oluf Dimitri; Chen, Duan. (2023) Clinical aspects in translational research on gastric tumorigenesis and development of new treatments*. Праці Наукового товариства імені Шевченка. Медичні науки
    Vitenskapelig oversiktsartikkel
  • Chen, Duan; Zhao, Chun-Mei. (2010) Complexity of Gastric Acid Secretion Revealed by Targeted Gene Disruption in Mice. Current pharmaceutical design
    Vitenskapelig oversiktsartikkel
  • Hayakawa, Yoku; Sakitani, Kosuke; Konishi, Mitsuru; Asfaha, Samuel; Niikura, Ryota; Tomita, Hiroyuki; Renz, Bernhard W.; Tailor, Yagnesh; Macchini, Marina; Middelhoff, Moritz. (2017) Nerve growth factor promotes gastric tumorigenesis through aberrant cholinergic signaling. Cancer Cell
    Vitenskapelig artikkel
  • Chen, Duan; Karlsson, Bjørn; Zhao, Chun-Mei; Wadstrom, T. (2007) Does Helicobacter pylori infection per se cause gastric cancer or duodenal ulcer? Inadequate evidence in Mongolian gerbils and inbred mice. FEMS Immunology and Medical Microbiology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Chen, D; Yamada, H.; delaCour, C. Dornonville; Lindström, E.; Persson, L.; Håkanson, R. (2003) Rat stomach ECL cells: mode of activation of histidine decarboxylase. Regulatory Peptides
    Vitenskapelig artikkel
  • Arum, Carl-Jørgen; Kodama, Yosuke; Rolim, Natale Pinheiro Lage; Widerøe, Marius; Anderssen, Endre; Viset, Trond; Otterlei, Marit; Lundgren, Steinar; Chen, Duan; Zhao, Chun-Mei. (2010) A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World Journal of Urology
    Vitenskapelig artikkel
  • Stenstrøm, Bjørn Olof; Zhao, Chun-Mei; Tømmerås, Karin; Arum, Carl-Jørgen; Chen, Duan. (2006) Is gastrin partially responsible for body weight reduction after gastric bypass?. European Surgical Research
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  • Zhao, Chun-Mei; Chen, Duan. (2012) The ECL Cell: Relay Station for Gastric Integrity. Current Medicinal Chemistry
    Vitenskapelig oversiktsartikkel
  • Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Bård Eirik; Chen, Duan. (2010) Eating Behavior in Rats Subjected to Vagotomy, Sleeve Gastrectomy, and Duodenal Switch. Journal of Gastrointestinal Surgery
    Vitenskapelig artikkel
  • Karlsson, Bjørn; Zhao, Chun-Mei; Rogers, AB; Nilsson, HO; Sturegard, E; Lundgren, Steinar; Fox, J; Wang, Timothy C.; Chen, Duan; Wadstrom, T. (2007) Swedish moist snuff accelerates gastric cancer development in Helicobacter pylori-infected wild-type and gastrin transgenic mice. Carcinogenesis
    Vitenskapelig artikkel
  • Furnes, Marianne; Zhao, Chun-Mei; Stenstrøm, Bjørn; Arum, Carl-Jørgen; Tømmerås, Karin; Kulseng, Bård Eirik; Chen, Duan. (2009) Feeding behavior and body weight development: Lessons from rats subjected to gastric bypass surgery or high-fat diet. Journal of Physiology and Pharmacology
    Vitenskapelig artikkel
  • Zheng, Liang; Xu, Jing; Qiu, Wanshan; Liu, Xiang; Zhao, Chun-Mei; Chen, Duan; Chen, Yi-Jiang. (2010) CARDIOPROTECTION OF EXOGENOUS ERYTHROPOIETIN IN MICE WITH LIGATURE-INDUCED AORTIC STENOSIS: EFFECTS ON MALADAPTIVE CARDIAC HYPERTROPHY. Journal of Physiology and Pharmacology
    Vitenskapelig artikkel
  • Resell, Mathilde Victoria; Stranden, Morten; Qvigstad, Gunnar; Chen, Duan; Zhao, Chun Mei. (2024) Gaps between needs of patient and public involvement and interests of researchers on pancreatic cancer. Patient Education and Counseling
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei; Hakanson, R; Samuelson, LC; Rehfeld, JF; Friis-Hansen, L. (2004) Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Gastroenterology
    Vitenskapelig artikkel
  • Cui, GL; Koh, TJ; Chen, Duan; Zhao, Chun-Mei; Takaishi, S; Dockray, GJ; Varro, A; Rogers, AB; Fox, JG; Wang, T. (2004) Overexpression of glycine-extended gastrin inhibits parietal cell loss and atrophy in the mouse stomach. Cancer Research
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  • Cai, Xing; Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Lundgren, Steinar; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2016) A Potential New Regimen (“Tricyclie”) for Treatment of Gastric Cancer: Targeting Glutamine-Dependent Wnt/β-Catenin-mTOR Signaling. Gastroenterology
    Konferanseabstract
  • Olsen, Magnus Kringstad; Johannessen, Helene; Ramracheya, Reshma; Zhao, Chun-Mei; Chen, Duan. (2018) New approaches for weight loss: Experiments using animal models. Current pharmaceutical design
    Vitenskapelig oversiktsartikkel
  • Sheng, Weiwei; Ermanno, Malagola,; Henrik, Nienhüser; Zhengyu, Zhang; Woosook, Kim; Leah, Zamechek; Antonia, Sepulveda; Masahiro, Hata; Yoku, Hayakawa; Zhao, Chun-Mei. (2020) Hypergastrinemia Expands Gastric ECL Cells Through CCK2R Progenitor Cells via ERK Activation. Cellular and Molecular Gastroenterology and Hepatology (CMGH)
    Vitenskapelig artikkel
  • Vigen, RA; Arum, Carl-Jørgen; Karlsson, Bjørn; Chen, Duan. (2006) A unique surgical model for studying the physiology of gastrin: Gastrocystoplasty and fundectomy. Scandinavian Journal of Laboratory Animal Science
    Vitenskapelig artikkel
  • Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Sousa, Mirta; Slupphaug, Geir; Kulseng, Bård Eirik; Chen, Duan. (2012) Eating Behavior and Glucagon-Like Peptide-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats Subjected to Ileal Interposition Associated with Sleeve Gastrectomy. Obesity Surgery
    Vitenskapelig artikkel
  • Cao, HaiLong; Xue, L; Xu, X; Wu, Y; Zhu, J; Chen, L; Chen, Duan; Chen, YJ. (2011) Heat shock proteins in stabilization of spontaneously restored sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery. Cell stress & chaperones (Print)
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Chen, D; Yamada, H.; delaCour, C. Dornonville; Lindström, E.; Persson, L.; Håkanson, R. (2003) Rat stomach ECL cells: mode of activation of histidine decarboxylase. Regulatory Peptides
    Vitenskapelig artikkel
  • Kopin, Alan S.; McBride, E.W.; Chen, Ci; Chen, Duan; Zhao, Chun-Mei; Beinborn, M. (2003) Identification of a series of CCK-2 receptor nonpeptide agonists: Sensitivity to stereochemistry and a receptor point mutation. PNAS
    Vitenskapelig artikkel
  • Egecioglu, E; Stenstrom, B; Pinnock, SB; Tung, LYC; Cour, CD de la; Lindqvist, A; Hakanson, R; Syversen, Unni; Chen, Duan; Dickson, SL. (2008) Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents. Regulatory Peptides
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Chen, Duan; Håkanson, Rolf. (2003) Rat stomach ECL cells: mode of activation of histidine decaroxylase. Regulatory Peptides
    Vitenskapelig artikkel
  • Vigen, Alexander; Kodama, Yosuke; Viset, Trond; Fossmark, Reidar; Waldum, Helge; Kidd, Mark; Wang, Timothy C.; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2013) Immunohistochemical evidence for an impairment of autophagy in tumorigenesis of gastric carcinoids and adenocarcinomas in rodent models and patients. Histology and Histopathology
    Vitenskapelig artikkel
  • Furnes, Marianne Waldum; Tømmerås, Karin; Arum, Carl-Jørgen; Zhao, Chun-Mei; Chen, Duan. (2008) Gastric bypass surgery causes body weight loss without reducing food intake in rats. Obesity Surgery
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  • Rydning, Astrid; Bakkelund, Karin Elvenes; Chen, Duan; Falkmer, Sture Emil; Grønbech, Jon Erik. (2004) Role of bradykinin on gastric vasodilation caused by hypertonic saline and acid back diffusion. Regulatory Peptides
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  • Hayakawa, Yoku; Jin, Guangchun; Wang, Hongshan; Chen, Xiaowei; Westphalen, Christoph B.; Asfaha, Samuel; Renz, Bernhard W.; Ariyama, Hiroshi; Dubeykovskaya, Zinaida A.; Takemoto, Yoshihiro. (2015) CCK2R identifies and regulates gastric antral stem cell states and carcinogenesis. Gut
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei. (2007) Genetically engineered mice: a new paradigm to study gastric physiology. Current Opinion in Gastroenterology
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  • Eiden, Lee E.; Gundlach, Andrew L.; Grinevich, Valery; Lee, Mary R.; Mecawi, André S.; Chen, Duan; Buijs, Ruud M.; Hernández, Vito S.; Fajardo-Dolci, Germán; Zhang, Li-Mei. (2020) Regulatory peptides and systems biology: A new era of translational and reverse-translational neuroendocrinology. Journal of Neuroendocrinology (JNE)
    Vitenskapelig oversiktsartikkel
  • Bernsand, Maria; Zhao, Chun-Mei; Chen, Duan; Håkanson, R; Stenstrøm, Bjørn; Norlén, Per. (2008) Ischemia mobilizes histamine but not pancreastatin from ECL cells of rat stomach: evidence for a cytosolic histamine compartment. Cell and Tissue Research
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  • Chen, Duan. (2004) ECL cells. Encyclopedia of Endocrinology and Endocrine Diseases
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  • Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan. (2021) Neural signaling modulates metabolism of gastric cancer. iScience
    Vitenskapelig artikkel
  • Chen, Duan; Furnes, Marianne Waldum; Zhao, Chun-Mei. (2009) Translational research on obesity: from bedside to bench. Journal of Physiology and Pharmacology
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  • Song, Zhigang; Bhagat, Govind; Quante, Michael; Baik, Gwang Ho; Marrache, Frederic; Tu, Shuiping; Zhao, Chun-Mei; Chen, Duan; Dannenberg, Andrew; Wang, Timothy C.. (2010) Potential carcinogenic effects of cigarette smoke and Swedish moist snuff on pancreas: a study using a transgenic mouse model of chronic pancreatitis. Laboratory Investigation
    Vitenskapelig artikkel
  • Wang, TC; Dangler, CA; Chen, D; Goldenring, JR; Koh, T; Raychowdhury, R; Coffey, RJ; Ito, S; Varro, A; Dockray, GJ. (2000) Synergistic Interaction Between Hypergastrinemia and Helicobacter Infection in a Mouse Model of Gastric Cancer. Gastroenterology
    Vitenskapelig artikkel
  • Chen, D; Zhao, CM; Norlen, P; Björkqvist, M; Ding, XQ; Kitano, M; Hakanson, R. (2000) Effect of cholecystokinin-2 receptor blockade on rat stomach ECL cells. A histochemical, electron-microscopic and chemical study. Cell and Tissue Research
    Vitenskapelig artikkel
  • Chen, D; Truong, T; Gaborieau, V; Byrnes, G; Chabrier, A; Chuang, SC; Olshan, AF; Weissler, MC; Luo, JC; Romkes, M. (2011) A Sex-Specific Association between a 15q25 Variant and Upper Aerodigestive Tract Cancers. Cancer Epidemiology, Biomarkers and Prevention
    Vitenskapelig artikkel
  • Björkqvist, Maria; Norlén, Per; Kitano, Masayuki; Chen, Duan; Zhao, Chun-Mei; delaCour, D Dornonville; Gagnemo-Persson, Rebecca; Håkanson, Rolf. (2001) Effects of CCK-2 receptor blockade on growth parameters in gastrointestinal tract and pancreas in rats. Pharmacology and Toxicology
    Vitenskapelig artikkel
  • Nieuwenhove, Yves van; Chen, Duan; Willems, Gerard. (2001) Postprandial cell proliferation in the esophageal epithelium of rats. Regulatory Peptides
    Vitenskapelig artikkel
  • Oostindjer, Marije; Alexander, Jan; Amdam, Gro Vang; Andersen, Grethe; Bryan, Nathan S.; Chen, Duan; Corpet, Denis E.; Smet, Stefaan De; Dragsted, Lars Ove; Haug, Anna. (2014) The role of red and processed meat in colorectal cancer development: a perspective. Meat Science
    Vitenskapelig oversiktsartikkel
  • Øverby, Anders; Rabben, Hanne-Line; Takahashi, Tetsufumi; Zhao, Chun Mei; Matsui, Hidenori; Nakamura, Masahiko; Chen, Duan. (2016) Possible mechanism-of-action of naturally occurring isothiocyanates in chemoprevention and adjuvant chemotherapy for gastric cancer. Gastroenterology
    Konferanseabstract
  • Rabben, Hanne-Line; Zhao, Chun-Mei; Hayakawa, Yoku; Wang, Timothy C.; Chen, Duan. (2016) Vagotomy and gastric tumorigenesis. Current Neuropharmacology
    Vitenskapelig oversiktsartikkel
  • Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Lyle, Robert; Bettencourt, Paulo; Miroljub, Popovic; Witter, Menno; Barrett, Perry. (2013) Role of the vagus nerve in the gut-brain axis revealed by stimulation and blockade of the gastric vagus nerve. Gastroenterology
    Konferanseabstract
  • Zhao, Chun Mei; Rabben, Hanne-Line; Resell, Mathilde Victoria; Ianevski, Aleksandr; Sharma, Animesh; Hagen, Lars; Diez Sanchez, Alberto; Martin Alonso, Mara; Qvigstad, Gunnar; Kainov, Denis. (2024) INHIBITION OF EXOSOMES SUPPRESSES THE PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA: A STUDY USING MOUSE MODELS AND HUMAN ORGANOIDS. United European Gastroenterology Journal (UEG Journal)
    Fagartikkel
  • Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Baad; Chen, Duan. (2010) Eating Behavior in Rats Subject to Vagotomy, Sleeve Gastrectomy and Duodenal Switch. Gastroenterology
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan. (2010) Gastric ECL cells, rather than gastric acid, play an important role in gut-bone axis. Gastroenterology
    Konferanseabstract
  • Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2010) Truncal vagotomy inhibited gastric cancer initiation in the INS-GAS mouse model. Gastroenterology
    Konferanseabstract
  • Brizozowski, Thomas; Sikiric, Predrag; Chen, Duan; Hahm, Ki-Baik; Seiwerth, Sven. (2022) Editorial: Protection and healing in the digestive system and other tissues: Novel factors, mechanisms, and pharmaceutical targets. Frontiers in Pharmacology
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  • Øverby, Anders; Zhao, Chun-Mei; Wang, Timothy C.; Bones, Atle M.; Chen, Duan. (2014) Gastric cancer chemoprevention by phenethyl isothiocyanate-containing diet in chemically - but not genetically - induced gastric cancer in mice. Gastroenterology
    Konferanseabstract
  • Furnes, Marianne Waldum; Stenstrøm, Bjørn; Tømmerås, Karin; Skoglund, Trine; Dickson, SL; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2008) Feeding behaviour in rats subjected to gastrectomy or gastric bypass surgery. European Surgical Research
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  • Arum, Carl-Jørgen; Tømmerås, Karin; Anderssen, Endre; Zhao, Chun-Mei; Chen, Duan. (2007) Gene expression profiling and pathway analysis of orthotopic rat bladder cancer model. European Urology. Supplement
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  • Zhao, Chun-Mei; Martinez, V; Piqueras, L; Wang, L-X; Taché, Y; Chen, Duan. (2008) Control of gastric acid secretion in somatostatin receptor 2 deficient mice: shift from endocrine/paracrine to neurocrine pathways. Endocrinology
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  • Zhao, Chun-Mei; Chen, Duan. (2007) Genetically engineered mice: a new paradigm to study gastric physiology. Stomach and duodenum. Current Opinion in Gastroenterology
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  • Zhao, Chun-Mei; Furnes, Marianne Waldum; Stenström, Björn; Kulseng, Bård Eirik; Chen, Duan. (2008) Characterization of obestatin- and ghrelin-producing cells in the gastrointestinal tract and pancreas of rats: an immunohistochemical and electron-microscopic study. Cell and Tissue Research
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  • Norlen, P.; Lindstrøm, E.; Zhao, Chun-Mei; Kitano, M.; Chen, Duan; Andersson, K.; Håkansson, R.. (2000) alpha-fluoromethylhistidine depletes histamine from secreting but not from non-secreting rat stomach ECL-cells. European Journal of Clinical Pharmacology
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  • Chen, Duan; Zhao, Chun-Mei; Dockray, Graham J.; Varro, Andrea; Hoek, Alfred van; Sinclair, Natalie F.; Wang, Timothy C.. (2000) Glycine-Extended Gastrin Synergizes With Gastrin 17 to Stimulate Acid Secretion in Gastrin-Deficient Mice. Gastroenterology
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  • Chen, Duan; Zhao, Chun-Mei. (2013) Signaling pathways in control of gastric acid secretion and food-stomach-bone axis revealed by gene expression profiling in the stomach of genetically targeted mice deficient in CCK1 receptor and gastrin/CCK2 receptor. The FASEB Journal
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  • Westerberg, I.; Walther, A; Guerrero, J-L; Coello, Z; Halldin, S; Xu, Chong-Yu; Chen, D; Lundin, L-C. (2010) Precipitation data in a mountainous catchment in Honduras: quality assessment and spatiotemporal characteristics. Theoretical and Applied Climatology
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  • Resell, Mathilde Victoria; Rabben, Hanne-Line; Sharma, Animesh; Hagen, Lars; Hoang, Linh; Skogaker, Nan Elisabeth Tostrup; Aarvik, Anne; Bjåstad, Eirik Knudsen; Svensson, Magnus Kringstad; Amrutkar, Manoj. (2025) Proteomics profiling of research models for studying pancreatic ductal adenocarcinoma. Scientific Data
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  • Resell, Mathilde Victoria; Rabben, Hanne-Line; Amrutkar, Manoj; Hagen, Lars; Batra, Surinder K.; Verbeke, Caroline Sophie; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun Mei. (2023) Mo1138 COMPARATIVE PROTEOMICS REVEALS TRANSLATIONAL POTENTIAL OF TARGETS FOR PANCREATIC DUCTAL ADENOCARCINOMA. Gastroenterology
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  • Chen, Duan; Friis-Hansen, L; Håkanson, R; Zhao, Chun-Mei. (2005) Genetic dissection of the signaling pathways that control gastric acid secretion. InflammoPharmacology
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  • Erlandsen, Sten Even; Qvigstad, Gunnar; Fossmark, Reidar; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian. (2012) Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach. Regulatory Peptides
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  • Zhao, Chun-Mei; Myrvold, Helge Elliot; Chen, Duan. (2014) Reduced neurons in the ileum of proctocolectomized rat models. Medical Molecular Morphology
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  • Andersen, Gøran Troseth; Lanevski, Aleksandr; Rabben, Hanne-Line; Geithus, Simon; Resell, Mathilde Victoria; Kodama, Yosuke; Tomita, Hiroyuki; Grønbech, Jon Erik; Wang, Timothy Cragin; Zhao, Chun Mei. (2023) GASTRIC INTESTINAL METAPLASIA VS. GASTRIC ADENOCARCINOMA OF PATIENTS: DISCTICT PHENOTYPIC TRAITS IN TRANSCRIPTOMICS. Gastroenterology
    Konferanseabstract
  • Zhao, Chun Mei; Rabben, Hanne-Line; Resell, Mathilde Victoria; Olsen, Magnus Kringstad; Cai, Xing; Zhang, Haiying; Batra, Surinder K.; Lyden, David C; Wang, Timothy Cragin; Chen, Duan. (2023) ARREST OF EXOCYTOSIS/ENDOCYTOSIS COUPLING INHIBITS PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA IN MICE. Gastroenterology
    Konferanseabstract
  • Zhao, Chun-Mei; Håkanson, Rolf; Chen, Duan. (2005) Secretory organelles in ECL cells: effects of pharmacological blockade of the gastrin/CCK2 receptor versus its elimination by gene targeting. InflammoPharmacology
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  • Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Sandvik, Arne Kristian; Chen, Duan. (2011) Stomach-Bone Axis: Possible Involvement of Signaling Pathways and Vitamin D Governing Bone Metabolism. Gastroenterology
    Konferanseabstract
  • Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Kulseng, Bård Eirik; Chen, Duan. (2011) Energy Metabolism Following High-Fat Diet and Bariatric Surgeries (Gastric Bypass, Sleeve Gastrectomy, Duodenal Switch and Ileum Transposition) in Rats. Gastroenterology
    Konferanseabstract
  • Olsen, Magnus Kringstad; Johannessen, Helene; Cassie, Nikki; Barrett, Perry; Takeuchi, Koji; Kulseng, Bård Eirik; Chen, Duan; Zhao, Chun-Mei. (2016) Steady-state energy balance in animal models of obesity and weight loss. Scandinavian Journal of Gastroenterology
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  • Andersen, Gøran Troseth; Ianevski, Aleksandr; Resell, Mathilde Victoria; Pojskic, Naris; Rabben, Hanne-Line; Geithus, Synne; Kodama, Yosuke; Tomita, Hiroyuki; Kainov, Denis; Grønbech, Jon Erik. (2024) Multi-bioinformatics revealed potential biomarkers and repurposed drugs for gastric adenocarcinoma-related gastric intestinal metaplasia. npj Systems Biology and Applications
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  • Øverby, Anders; Zhao, Chun-Mei; Chen, Duan. (2014) Plant phytochemicals: Potential anticancer agents against gastric cancer. Current opinion in pharmacology (Print)
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  • Gudbrandsen, Oddrun Anita; Kodama, Yosuke; Mjøs, Svein Are; Zhao, Chun-Mei; Johannesen, Helene; Brattbakk, Hans-Richard; Haugen, Christine; Kulseng, Bård Eirik; Mellgren, Gunnar; Chen, Duan. (2014) Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats. Nutrition & Diabetes
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  • Kodama, Yosuke; Zhao, Chun-Mei; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne; Beisvag, Vidar; Johannessen, Helene; Hayakawa, Yoku; Tomita, Hiroyuki. (2013) Denervation Suppresses Gastric Cancer Initiation and Progression Through Inhibition of the Cancer Niche. Gastroenterology
    Konferanseabstract
  • Vigen, Reidar Alexander; Kidd, Mark; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2011) Ultrastructral Evidence for a Mechanism of ECL Cell Transformation to Gastric Carcinoid in Mastomys Involving Impairment of Autophagy and Loss of Gastrin Control. Gastroenterology
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  • Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Sandvik, Arne Kristian; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2011) Evidence for Mechanism of Vagal Innervation in Gastric Cancer Initiation Involving Signaling Pathways Governing Stem Cells in Mice. Gastroenterology
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  • Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Krokan, Hans Einar; Chen, Duan; Hjelme, Dag Roar; Svaasand, Lars O.. (2006) Monitoring of hALA induced PDT in rat bladder cancer by optical spectroscopy. Lasers in Surgery and Medicine
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  • Johannessen, Helene; Kodama, Yosuke; Cao, HaiLong; Kulseng, Baard; Zhao, Chun-Mei; Chen, Duan. (2011) Eating Behavior in Rats Subjected to Ileum Transposition and Sleeve Gastrectomy. Gastroenterology
    Konferanseabstract
  • Okabe, Susumu; Okamoto, Toshihiro; Zhao, Chun-Mei; Chen, Duan; Matsui, Hirofumi. (2014) Acetic acid induces cell death: An in vitro study using normal rat gastric mucosal cell line and rat and human gastric cancer and mesothelioma cell lines. Journal of Gastroenterology and Hepatology
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  • Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Beisvag, Vidar; Kulseng, Bård Eirik; Sandvik, Arne Kristian; Rehfeld, Jens F.; Chen, Duan. (2014) Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Regulatory Peptides
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  • Zhao, Chun-Mei; Wang, X; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T; Chen, Duan. (2003) Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastrin-deficient mice. Regulatory Peptides
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  • Waldum, Camilla; Zhao, Chun-Mei; Waldum, Helge; Halgunset, Jostein; Chen, Duan. (2003) Cheese-induced body weight gain is not accompanied by an increase of gastric cells producing leptin, gastrin, or pancreastatin in mice. Scandinavian Journal of Laboratory Animal Science
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  • Chen, Duan; Håkanson, Rolf; Rehfeld, Jens F.; Zhao, Chun-Mei. (2002) CCK2 receptors are necessary for the differentiation and proliferation of ECL cells in mouse and rat stomach. Immunopharmacology
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  • Aihara, T.; Fujishita, T.; Kanatani, K.; Furutani, K.; Nakamura, E.; Taketo, M.M.; Matsui, M.; Chen, Duan; Okabe, S.. (2003) Impaired gastric secretion and lack of trophic responses to hypergastrinemia in M3 muscarinic receptor-knockout mice. Gastroenterology
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  • Waldum, C.; Zhao, C.M.; Waldum, Helge; Halgunset, Jostein; Chen, Duan. (2003) Cheese-induced body weight is not accompained by an increase of gastric cells producing leptin, ghrelin, gastrin, or pancreastatin in mice. Scandinavian Journal of Laboratory Animal Science
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  • Kopin, Alan S.; McBride, E.W.; Ren, Y.; Chen, Duan; Zhao, C.M.. (2003) Identification of a series of CCK-2 receptor nonpeptide agonists: sensitivity to stereochemistry and a receptor point mutation. Proceedings of the National Academy of Sciences of the United States of America (PNAS)
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  • Cui, G; Koh, T.; Chen, Duan; Zhao, C.M.; Dockery, J.; Varro, A; Fox, J; Wang, T. (2003) Overexpression of glycine-extended gastrin maintains acid secretion and prevents the development of preneoplasia in the stomach via reducing parietal cell lost in transgenic mice. Gastroenterology
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  • Egecioglu, E; Karlsson, Bjørn; Pinnock, S B; Tung, LYC; Cour, C Dornonville de la; Lindqvist, A; Håkanson, R; Syversen, Unni; Chen, Duan; Dickson, SL. (2007) Hypothalamic gene expression following ghrelin therapy to gastrectomized rodents. Regulatory Peptides
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  • Ramracheya, Reshma; McCulloch, Laura J.; Clark, Anne; Olsen, Magnus Kringstad; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) Roux-En-Y Gastric Bypass Surgery Restores Impaired Islet Architecture and Function in Type-2 Diabetes by Elevation of Plasma PYY. Gastroenterology
    Konferanseabstract
  • Zhao, C-M; Wang, X.; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T; Chen, Duan. (2003) Chronic Helicobacter pylori infection results in gastric hypoacidity and hypergastrinemia in wild-type mice but vagally induced hypersecretion in gastroindeficient mice. Regulatory Peptides
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  • Chen, Duan; Rehfeld, Jens Frederik; Watts, Alan G; Rorsman, Patrik; Gundlach, Andrew L.. (2023) History of key regulatory peptide systems and perspectives for future research. Journal of Neuroendocrinology (JNE)
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  • Chen, Duan; Hagen, Susan J; Boyce, Malcolm; Zhao, Chun Mei. (2023) Neuroendocrine mechanism of gastric acid secretion: Historical perspectives and recent developments in physiology and pharmacology. Journal of Neuroendocrinology (JNE)
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  • Hayakawa, Yoku; Asfaha, Samuel; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor,, Yagnesh H.; Nagar,, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF Promotes Gastrointestinal Cancer Development Through Tumor-Associated Neurogenesis. Gastroenterology
    Konferanseabstract
  • delaCour, D Dornonville; Björkqvist, Maria; Sandvik, Arne Kristian; Håkanson, Rolf; Chen, D. (2001) A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control. Regulatory Peptides
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  • Zhao, Chun-Mei; Bakke, Ingunn; Tostrup-Skogaker, Nan; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research
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  • Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne Kristian; Fox, James G.; Kaneko, Kazuhiro; Wang, Timothy C.. (2012) Vagotomy Suppresses Gastric Cancer Progression in Mice. Gastroenterology
    Konferanseabstract
  • Kodama, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan. (2012) Gastric Bypass and Duodenal Switch Cause Body Weight Loss Through Different Mechanisms in Rats. Gastroenterology
    Konferanseabstract
  • Johannessen, Helene; Olsen, Magnus Kringstad; Cassie, Nikki; Barrett, Perry; Rehfeld, Jens F.; Holst, Jens J.; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2014) Preclinical Trial of Gastric Injection of Botulinum Toxin Type A as Weight-Loss-Surgery. Gastroenterology
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  • Chen, Duan; Håkanson, R. (2003) Mechanism of gastric ECL-cell tumor induction: Observations in the rat. WHO IARC Technical Publication
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  • Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan. (2012) Evidence for the Hindgut Hypothesis After Ileal Interposition Associated With Sleeve Gastrectomy: Increased Number of GLP-1-Producing Cells in Interposed Ileum and Pancreatic Islets in Rats. Gastroenterology
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  • Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan; Zhao, Chun-Mei. (2012) Food Intake Associated Gene Expression Profiles in the Stomach of Genetically Targeted Mice Deficient in CCK1 Receptor and/or CCK2 Receptor. Gastroenterology
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  • Vigen, Alexander; Kodama, Yosuke; Viset, Trond; Fossmark, Reidar; Waldum, Helge; Kidd, Mark; Wang, Timothy C.; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2012) Impaired Autophagy in Gastric Carcinoids and Adenocarcinoma of Both Rodent Models and Patients. Gastroenterology
    Konferanseabstract
  • Martinsen, Tom Christian; Bakke, I; Chen, Duan; Aamo, T; Zahlsen, Kolbjørn; Waldum, Helge. (2003) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPARa receptors. Gastroenterology
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  • Chen, Duan; Olsen, Magnus Kringstad; Strømmen, Magnus; Johannessen, Helene; Bjøru, Hege Tevik; Salater, Sissel; Johnsen, Gjermund; Mårvik, Ronald; Zhao, Chun-Mei; Kulseng, Bård Eirik. (2016) Intragastric Injection of Botulinum Toxin a to Treat Obesity: Mechanism of Action and a Randomized, Double-Blind, Placebo-Controlled Phase II Trial With Open-Label Extension Study. Gastroenterology
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  • Ramracheya, Reshma D.; McCulloch, Laura J.; Clark, Anne; Wiggins, David; Johannessen, Helene; Olsen, Magnus Kringstad; Cai, Xing; Zhao, Chun-Mei; Chen, Duan; Rorsman, Patrik. (2016) PYY-Dependent Restoration of Impaired Insulin and Glucagon Secretion in Type 2 Diabetes following Roux-En-Y Gastric Bypass Surgery. Cell reports
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  • Zhao, Chun-Mei; Fossmark, Reidar; Martinsen, Tom Christian; Kawase, Shiro; Chen, Duan; Waldum, Helge. (2005) Dedifferentiation of enterochromaffin-like cells in gastric cancer of hypergastrinemic cotton rats. APMIS - Journal of Pathologiy, Microbiology and Immunology
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  • Olsen, Magnus Kringstad; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2015) Comparison of different surgical procedures in animal models for a better consideration of personalized bariatric surgery. Gastroenterology
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  • Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2015) 565Glutamine Metabolism As a Therapeutic Target for Gastric Cancer: Effects of Vagotomy Gastroenterology,Volume 148, Issue 4, Supplement 1, April 2015, Pages S-565–S-566. Gastroenterology
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  • Cui, Guanglin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Long-term omeprazole treatment suppress body weight gain and bone mineralization in young male rats. Scandinavian Journal of Gastroenterology
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  • Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Johnsen, Gjermund; Mårvik, Ronald; Kulseng, Bård Eirik; Chen, Duan; Revesz, David; Kuhn, Georg; Thorlin, Thorleif. (2012) Altered Eating Behavior by Subdiaphragmatic Truncal Vagus Nerve Stimulation in Rats. Gastroenterology
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  • Zhao, Chun-Mei; Yoku, Hayakawa; Westphalen,, Christoph B; Muthupalani,, Sureshkumar; Johannessen, Helene; Andersen, Gøran Troseth; Fox,, James G; Wang,, Timothy C.; Chen, Duan. (2014) Preclinical Trial of Botulinum Toxin Type a Injection in the Treatment of Gastric Cancer. Gastroenterology
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  • Zhao, Chun-Mei; Mark, Kidd,; Chen, Duan. (2014) Triple Roles of Autophagy in Cytoprotection, Cell Death and Tumorigenesis With Special Reference to Gastric ECL Cells. Gastroenterology
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  • Guida, Claudia; Stephen, Sam D.; Watson, Michael; Dempster, Niall; Larraufie, Pierre; Marjot, Thomas; Cargill, Tamsin; Rickers, Lisa; Pavlides, Michael; Tomlinson, Jeremy. (2019) PYY plays a key role in the resolution of diabetes following bariatric surgery in humans. EBioMedicine
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  • Guida, Claudia; McCulloch, Laura J.; Godazgar, Mahdieh; Stephen, Sam D.; Baker, Charlotte; Basco, Davide; Dong, Jiawen; Chen, Duan; Clark, Anne; Ramracheya, Reshma D.. (2018) Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYY. Diabetes, obesity and metabolism
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  • Håkanson, Rolf; Chen, Duan; Lindström, Erik; Bernsand, Maria; Norlén, Per. (2001) Control of secretion from rat stomach ECL cells in situ and in primary culture. Scandinavian Journal of Clinical and Laboratory Investigation
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  • Arum, Carl-Jørgen; Gederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Hjelde, Astrid; Krokan, Hans Einar; Svaasand, Lars O.; Chen, Duan; Zhao, Chun-Mei. (2011) Tissue responses to hexyl 5-aminolevulinate-induced photodynamic treatment in syngeneic orthotopic rat bladder cancer model: possible pathways of action. Journal of Biomedical Optics
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  • Chen, Duan; Zhao, Chun-Mei. (2012) Importance of Translational Research in GI Pharmacology: Lessons Learned from the Successes in History. Frontiers of gastrointestinal research
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  • Øverby, Anders; Zhao, Chun-Mei; Bones, Atle M.; Chen, Duan. (2014) Naturally occurring phenethyl isothiocyanate-induced inhibition of gastric cancer cell growth by disruption of microtubules. Journal of Gastroenterology and Hepatology
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  • Lindström, Erik; Chen, Duan; Norlén, Per; Andersson, Kjell; Håkanson, Rolf. (2001) Control of gastric acid secretion: the gastrin-ECL cell - parietal cell axis. Comparative Biochemistry and Physiology A
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  • Fykse, Vidar; Solligård, Erik; Bendheim, Marianne Østensen; Chen, Duan; Grønbech, Jon Erik; Sandvik, Arne Kristian; Waldum, Helge. (2006) ECL cell histamine mobilization and parietal cell stimulation in the rat stomach studied by microdialysis and electron microscopy. Acta Physiologica
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  • Stenstrøm, Bjørn; Løseth, Kirsti; Bevanger, Lars Solbu; Sturegård, E; Wadstrøm, T; Chen, Duan. (2005) Gastric bypass surgery does not increase susceptibility to Helicobacter pylori infection in the stomach of rat or mouse. InflammoPharmacology
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  • Arum, Carl-Jørgen; Vigen, RA; Karlsson, Bjørn; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2005) Acid secretion in urinary bladder of rats subjected to gastrocystoplasty. InflammoPharmacology
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  • Fossmark, Reidar; Zhao, Chun-Mei; Martinsen, Tom Christian; Kawase, Shiro; Chen, Duan; Waldum, Helge. (2005) Dedifferentiation of enterochromaffin-like cells in gastric cancer of cotton rats. APMIS - Journal of Pathologiy, Microbiology and Immunology
    Vitenskapelig artikkel
  • Martinsen, Tom Christian; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian; Zahlsen, Kolbjørn; Aamo, T.; Waldum, Helge. (2005) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alfa. American Journal of Physiology - Gastrointestinal and Liver Physiology
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  • Chen, Duan; Ayala, Gustavo E. (2018) Innervating Prostate Cancer. New England Journal of Medicine
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  • Okabe, Susumu; Kodama, Yosuke; Cao, HaiLong; Johannessen, Helene; Zhao, Chun-Mei; Wang, TC; Takahashi, Rei; Chen, Duan. (2012) Topical application of acetic acid in cytoreduction of gastric cancer model in mice. A technical report. Journal of Gastroenterology and Hepatology
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  • Vigen, Reidar Alexander; Chen, Duan; Syversen, Unni; Stunes, Astrid Kamilla; Håkanson, Rolf; Zhao, Chun-Mei. (2011) Serum gastrin and gastric enterochromaffin-like cells during estrous cycle, pregnancy and lactation, and in response to estrogen-like agents in rats. Journal of Physiology and Pharmacology
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  • Zhao, Chun-Mei; Kodama, Yosuke; Sandvik, Arne Kristian; Chen, Duan. (2009) Differentiation of Gastric ECL Cells in CCK 1+2 Receptor Double Knockout Mice. Gastroenterology
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  • Song, Zhigang; Bhagat, Govind; Baik, Gwang Ho; Gordon, Shanisha A.; Mitchell, Anthony; Zhao, Chun-Mei; Chen, Duan; Dannenberg,, Andrew; Wang, Timothy C.. (2009) Development of a Mouse Model of Inflammation-Dependent Pancreatic Cancer. Gastroenterology
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  • Dragsted, Lars Ove; Alexander, Jan; Amdam, Gro Vang; Bryan, Nathan S.; Chen, Duan; Haug, Anna; Karlsson, Anders H.; Kok, Theo M. de; Kulseng, Bård Eirik; Jr, Roy J. Martin. (2014) Letter to the Editor: Colorectal cancer risk and association with red meat - Is it inconsistent? Answer to the letter by Corpet, De Smet and Demeyer. Meat Science
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  • Chen, Duan; Zhao, Chun-Mei. (2011) The possible existence of a gut-bone axis suggested by studies of genetically manipulated mouse models?. Current pharmaceutical design
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  • Vigen, Alexander; Kidd, Mark; Modlin, IM; Chen, Duan; Zhao, Chun-Mei. (2012) Ultrastructure of ECL cells in Mastomys after long-term treatment with H-2 receptor antagonist loxtidine. Medical Molecular Morphology
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  • Cao, HaiLong; Xue, L; Xu, X; Wu, Y; Zhu, J; Chen, L; Chen, Duan; Chen, YJ. (2011) Heat shock proteins in stabilization of spontaneously restorted sinus rhythm in permanent atrial fibrillation patients after mitral valve surgery. Cell stress & chaperones (Print)
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  • Salome, N; Taube, M; Egecioglu, E; Hansson, C; Karlsson, Bjørn; Chen, Duan; Andersson, DR; Georg-Kuhn, H; Ohlsson, C; Dickson, SL. (2011) Gastrectomy alters emotional reactivity in rats: neurobiological mechanisms. European Journal of Neuroscience
    Vitenskapelig artikkel
  • Qiu, Wanshan; Zheng, Liang; Gu, Haiyong; Chen, Duan; Chen, Yijiang. (2008) Comparison between adult and infant lung injury in a rabbit ischemia-reperfusion model. Journal of Thoracic and Cardiovascular Surgery
    Vitenskapelig artikkel
  • Qiu, Wanshan; Gu, Haiyong; Zheng, Liang; Zhou, Jianwei; Chen, Duan; Chen, Yijiang. (2008) Pretreatment with edaravone reduces lung mitochondrial damage in an infant rabbit ischemia-reperfusion model. Journal of Pediatric Surgery
    Vitenskapelig artikkel
  • Johannesen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens F.; Plasse, Geoffrey van der. (2016) Erratum to: Vagal Blocking for Obesity Control: a Possible Mechanism-Of-Action (OBES SURG, 10.1007/s11695-016-2278-x). Obesity Surgery
    Korrigendum
  • Dubeykovskaya, Z; Si, Y; Chen, X; Worthley, DL; Renz, BW; Urbanska, AM; Hayakawa, Y; Xu, T; Westphalen, CB; Dubeykovskiy, A. (2016) Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. Nature Communications
    Vitenskapelig artikkel
  • Zhi, Xiaofei; Wu, Feijing; Qian, Jin; Ochiai, Yosuke; Lian, Guodong; Malagola, Ermanno; Zheng, Biyun; Tu, Ruhong; Zeng, Yi; Kobayashi, Hiroki. (2025) Nociceptive neurons promote gastric tumour progression via a CGRP–RAMP1 axis. Nature
    Vitenskapelig artikkel
  • Resell, Mathilde Victoria; Graarud, Elisabeth Pimpisa; Rabben, Hanne-Line; Sharma, Animesh; Hagen, Lars; Hoang, Linh; Skogaker, Nan Elisabeth Tostrup; Aarvik, Anne; Svensson, Magnus Kringstad; Amrutkar, Manoj. (2025) Knowledge Discovery in Databases of Proteomics by Systems Modeling in Translational Research on Pancreatic Cancer. Proteomes
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Hayakawa, Yoku; Kodama, Yosuke; Muthupalani, Sureshkumar; Westphalen,, Christoph B.; Andersen, Gøran Troseth; Flatberg, Arnar; Johannessen, Helene; Friedman, Richard A.; Renz, Bernhard W.. (2014) Denervation suppresses gastric tumorigenesis. Science Translational Medicine
    Vitenskapelig artikkel
  • Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2009) Gene expression profiles of bladder cancer: Comparison between orthotopic rat bladder cancer model and human bladder cancer patients. European Urology. Supplement
    Konferanseabstract
  • Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Gederaas, Odrun Arna; Arum, Carl-Jørgen; Hjelde, Astrid; Zhao, Chun-Mei; Chen, Duan; Krokan, Hans Einar; Svaasand, Lars O.. (2008) Monitoring of Hexyl 5-aminolevulinate Induced Photodynamic Therapy in Rat Bladder Cancer by Optical Spectroscopy. Journal of Biomedical Optics
    Vitenskapelig artikkel
  • Waldum, Camilla; Zhao, Chun-Mei; Chen, Duan. (2001) Are current textbooks good enough for physiology education? For example, the ECL-cells are missing. Advances in Physiology Education
    Vitenskapelig artikkel
  • Cui, G.-L.; Syversen, Unni; Chao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Long-term Omeprazole treatment Suppresses Body Weight Gain and Bone Mineralization in Young Male Rats. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel
  • Chen, Duan; Zhao, Chun-Mei; Falkmer, Sture Emil; Waldum, Helge; Syder, Andrew; Gordon, Jeffrey. (2001) Ablation of Parietal Cells Is Associated with ECL-cell Hyperplasia in Transgenic Mice with a Genetically Engineered Ablation of Their Parietal Cell Lineage. Gastroenterology
    Vitenskapelig artikkel
  • Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Barrett, Perry; Dickson, Suzanne; Holst, Jens; Rehfeld, Jens; Plasse, Geoffrey van der. (2016) Vagal blocking for obesity control: a possible mechanism-of-action. Obesity Surgery
    Vitenskapelig artikkel
  • Hutchinson, Lloyd; Stenström, Björn; Chen, Duan; Piperdi, Bilal; Levey, Sara; Lyle, Stephen; Wang, Timothy C.; Houghton, J. (2011) Human Barrett's adenocarcinoma of the esophagus, associated myofibroblasts, and endothelium can arise from bone marrow-derived cells after allogeneic stem cell transplant. Stem Cells and Development
    Vitenskapelig artikkel
  • Liu, Yanhua; Zhu, Lijun; Pan, Ya; Sun, Lizhou; Chen, Duan; Li, Xiaonan. (2012) Adiponectin Levels in Circulation and Breast Milk and mRNA Expression in Adipose Tissue of Preeclampsia Women. Hypertension in Pregnancy
    Vitenskapelig artikkel
  • Boyce, Malcolm; Dowen, Sally; Turnbull, Gillian; Berg, Frans van den; Zhao, Chun-Mei; Chen, Duan; Black, James. (2015) Effect of netazepide, a gastrin/CCK2 receptor antagonist, on gastric acid secretion and rabeprazole-induced hypergastrinaemia in healthy subjectshypergastrinaemia in healthy subjects. British Journal of Clinical Pharmacology
    Vitenskapelig artikkel
  • Vigen, Alexander; Chen, Duan; Zhao, Chun-Mei. (2012) Pathobiology of Gastric Carcinoids and Adenocarcinomas in Rodent Models and Patients: Studies of Gastrocystoplasty, Gender-Related Factors and Autophagy. Frontiers of gastrointestinal research
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Bakke, Ingunn; Skogaker, Nan Elisabeth Tostrup; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research
    Vitenskapelig artikkel

Del av bok/rapport

  • Chen, Duan. (2004) ECL cells in a physiological context.
    Vitenskapelig kapittel
  • Chen, Duan. (2004) Absence of the cholecystokinin2 receptor alters the structure and function of gastric parietal and ECL cells.
    Vitenskapelig kapittel
  • Zhao, Chun-Mei; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård; Chen, Duan. (2013) Galanin.
    Faglig kapittel

Studentoppgave eller avhandling

  • Helander, Linda; Krokan, Hans Einar; Gederaas, Odrun Arna; Johnsson, Anders Carl G.; Chen, Duan. (2015) Hexylaminolevulinate Photodynamic Treatment of Cancer Cell Lines. PhD Thesis. Tapir Akademisk Forlag
    Doktoravhandling
  • Andersen, Gøran Troseth; Chen, Duan; Grønbech, Jon Erik; Zhao, Chun Mei. (2023) Clinical Aspects in Translational Research on Gastric Tumorigenesis and Development of New Treatments. Norges teknisk-naturvitenskapelige universitet
    Doktoravhandling
  • Furnes, Marianne Waldum; Chen, Duan. (2008) Feeding behaviour and body weight developement: lessons from rats. Tapir Akademisk Forlag
    Doktoravhandling
  • Chen, Duan. (2008) Feeding Behavior and Body Weight Development: Lessons from rats. NTNU
    Doktoravhandling

Undervisning

Emner

  • MOL3000 - Innføring i molekylærmedisin
  • MOL8001 - Molekylær fysiologi: mekanismer og metoder
  • MOL3100 - Innføring i molekylærmedisin med prosjektoppgave

MD4020 Medisin - 1D Molekylær cellebiologi og medisinsk genetikk (Endocrinology and Metabolism)

 

Formidling

2024

  • Konferanseforedrag
    Zhao, Chun Mei; Chen, Duan. (2024) INHIBITION OF EXOSOMES SUPPRESSES PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA IN MICE AND HUMAN ORGANOIDS. Mid-Norge Gastroenterology Forum
  • Konferanseposter
    Resell, Mathilde Victoria; Rabben, Hanne-Line; Sharma, Animesh; Hagen, Lars; Hoang, Linh; Skogaker, Nan Elisabeth Tostrup; Aarvik, Anne; Svensson, Magnus K.; Amrutkar, Manoj; Verbeke, Caroline S.. (2024) PROTEOMICS-BASED SYSTEM MODELING REVEALED POTENTIAL TRANSLATIONAL TARGETS OF PANCREATIC DUCTAL ADENOCARCINOMA. UEG week 2024
  • Konferanseforedrag
    Zhao, Chun Mei; Chen, Duan. (2024) INHIBITION OF EXOSOMES SUPPRESSES PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA IN MICE AND HUMAN ORGANOIDS. UEG week 2024
  • Konferanseposter
    Andersen, Gøran Troseth; Ianevski, Aleksandr; Resell, Mathilde Victoria; Pojskic, Naris; Rabben, Hanne-Line; Geithus, Synne; Kodama, Yosuke; Tomita, Hiroyuki; Kainov, Denis; Grønbech, Jon Erik. (2024) Multi-bioinformatics revealed potential biomarkers and repurposed drugs for gastric adenocarcinoma-related gastric intestinal metaplasia. UEG week 2024

2023

  • Konferanseforedrag
    Zhao, Chun Mei; Chen, Duan. (2023) Preclinical development of PDAC treatment targeting exocytosis/endocytosis coupling. Nasjonal møte om pankreaskreft
  • Konferanseforedrag
    Andersen, Gøran Troseth; Lanevski, Aleksandr; Rabben, Hanne-Line; Geithus, Simon; Resell, Mathilde Victoria; Kodama, Yosuke; Tomita, Hiroyuki; Grønbech, Jon Erik; Wang, Timothy Cragin; Zhao, Chun Mei. (2023) GASTRIC INTESTINAL METAPLASIA VS. GASTRIC ADENOCARCINOMA OF PATIENTS: DISCTICT PHENOTYPIC TRAITS IN TRANSCRIPTOMICS. Digestive Disease Week 2023
  • Konferanseforedrag
    Resell, Mathilde Victoria; Rabben, Hanne-Line; Amrurkar, Manoj; Hagen, Lars; Batra, Surinder K.; Verbeke, Caroline Sophie; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun Mei. (2023) COMPARATIVE PROTEOMICS REVEALS TRANSLATIONAL POTENTIAL OF TARGETS FOR PANCREATIC DUCTAL ADENOCARCINOMA. Digestive Disease Week 2023
  • Konferanseforedrag
    Zhao, Chun Mei; Rabben, Hanne-Line; Resell, Mathilde Victoria; Olsen, Magnus Kringstad; Cai, Xing; Zhang, Haiying; Batra, Surinder K.; Lyden, David C; Wang, Timothy Cragin; Chen, Duan. (2023) ARREST OF EXOCYTOSIS/ENDOCYTOSIS COUPLING INHIBITS PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA IN MICE. Digestive Disease Week 2023

2022

  • Konferanseforedrag
    Zhao, Chun-Mei; Chen, Duan; Rabben, Hanne-Line; Wang, Timothy Cragin. (2022) Drug-Repurposing for Treatment of Gastric Cancer. 24th International Symposium on Regulatory Peptides (RegPep24)
  • Konferanseforedrag
    Chen, Duan; Zhao, Chun-Mei. (2022) Peptides and the Gut: the unfinished story of gastrin. 24th International Symposium on Regulatory Peptides (RegPep24)

2019

  • Konferanseposter
    Zhao, Chun-Mei; Zhu, Yanping; Hao, Yanpeng; Wang, Zhiqiang; Wang, Li; Chen, Duan. (2019) USE OF PATIENT-DERIVED TUMOR XENOGRAFT MODEL TO GUIDETREATMENT DECISIONS FOR PATIENTS. DDW 2019
  • Konferanseforedrag
    Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei. (2019) 531 – Targeting Nerve-Cancer Metabolism Improved Overall Survival in Aged Mice with Gastric Cancer. Scientific meeting

2016

  • Intervju
    Chen, Duan; Zhao, Chun-Mei; Olsen, Magnus Kringstad; Rabben, Hanne-Line; Andersen, Gøran Troseth. (2016) Fant hormon som kan bli medisin mot diabetes.
  • Intervju
    Chen, Duan; Zhao, Chun-Mei; Olsen, Magnus Kringstad; Rabben, Hanne-Line; Andersen, Gøran Troseth. (2016) Nytt norsk funn kan ta knekken på diabetes.
  • Intervju
    Olsen, Magnus Kringstad; Chen, Duan; Zhao, Chun-Mei. (2016) NTNU-forskere fant hormon som kan ta knekken på diabetes.
  • Konferanseforedrag
    Beisvag, Vidar; Bakke, Ingunn; Andersen, Gøran Troseth; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge; Sandvik, Arne Kristian. (2016) Signet ring cell carcinomas identified as a molecular subtype of gastric cancer. Digestive Disease Week 2016

2015

  • Konferanseforedrag
    Hayakawa, Yoku; Samuel, Asfaha; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor, Yagnesh H.; Nagar, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF promotes gastrointestinal cancer development through tumor-associated neurogenesis. AACR 2015
  • Foredrag
    Andersen, Gøran Troseth; Zhao, Chun-Mei; Chen, Duan. (2015) Denervation suppresses gastric tumorigenesis by inhibiting WNT signaling: a preclinical study. WNT and SHH meets Energy Metabolism
  • Foredrag
    Andersen, Gøran Troseth; Kodama, Yosuke; Rabben, Hanne-Line; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2015) GLUTAMINE METABOLISM AS A THERAPEUTIC TARGET FOR GASTRIC CANCER: EFFECTS OF DENERVATION. 15th International Conference on ULcer Research
  • Intervju
    Egelandsdal, Bjørg; Haug, Anna; Chen, Duan. (2015) Ingen grunn til kjøttpanikk.
  • Konferanseforedrag
    Cai, Xing; Rabben, Hanne-Line; Chen, Duan; Zhao, Chun-Mei. (2015) Inhibition of metabolism and mTOR signalling for treatment of gastric cancer: A preliminary study in vitro and in animal model of spontaneous gastric cancer. WNT and SHH meets Energy Metabolism
  • Konferanseforedrag
    Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Wang, Timothy C.; Chen, Duan; Zhao, Chun-Mei. (2015) Glutamine metabolism as a therapeutic target for gastric cancer: effects of vagotomy. AACR 2015
  • Konferanseforedrag
    Andersen, Gøran Troseth; Kodama, Yosuke; Hayakawa, Yoku; Vettukattil, Riyas; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei. (2015) Glutamine Metabolism As a Therapeutic Target for Gastric Cancer: Effects of Vagotomy Gastroenterology,Volume 148, Issue 4, Supplement 1, April 2015, Pages S-565–S-566. DDW 2015
  • Konferanseforedrag
    Hayakawa, Yoku; Asfaha, Samuel; Renz, Bernhard W.; Westphalen, Christoph B.; Tailor,, Yagnesh H.; Nagar,, Karan K.; Worthley, Daniel L.; Chen, Duan; Wang, Timothy C.. (2015) NGF Promotes Gastrointestinal Cancer Development Through Tumor-Associated Neurogenesis. DDW2015
  • Konferanseforedrag
    Olsen, Magnus Kringstad; Johannessen, Helene; Kodama, Yosuke; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2015) Comparison of different surgical procedures in animal models for a better consideration of personalized bariatric surgery. DDW 2015

2014

  • Intervju
    Chen, Duan. (2014) Tester Botox i kampen mot kreft.
  • Intervju
    Chen, Duan. (2014) Botox mot kreft.
  • Intervju
    Chen, Duan. (2014) El bótox podría usarse para tratar el cáncer.
  • Intervju
    Chen, Duan. (2014) New Wrinkle for Botox: Drug May Treat Stomach Cancers.
  • Intervju
    Chen, Duan. (2014) Botox may slow tumor growth in stomach cancer.
  • Intervju
    Chen, Duan. (2014) The other use for botox.
  • Konferanseforedrag
    Zhao, Chun-Mei; Hayakawa, Yoku; Kodama, Yosuke; Westphalen,, Christoph Benedikt; Muthupalani,, Sureshkumar; Johannessen, Helene; Andersen, Gøran Troseth; Fox,, James G.; Wang,, Timothy C.; Chen, Duan. (2014) Preclinical trial of botulinum toxin type A for treatment of gastric Cancer. WCP2014
  • Konferanseposter
    Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Olsen, Magnus Kringstad; Lyle, Robert; Barrett, Perry; Dickson, Suzanne L.; Holst, Jens J.. (2014) The role of vagus nerve in the brain-gut axis: a target for obesity treatment. WCP2014
  • Konferanseposter
    Zhao, Chun-Mei; Kidd, Mark; Chen, Duan. (2014) Triple Roles of Autophagy in Cytoprotection, Cell Death and Tumorigenesis with Special Reference to Gastric ECL cell. WCP2014
  • Intervju
    Chen, Duan; Andersen, Gøran Troseth; Kulseng, Bård Eirik; Tronvik, Erling. (2014) – Botox kan bli en ny kreftkur.
  • Intervju
    Kulseng, Bård Eirik; Tronvik, Erling; Andersen, Gøran Troseth; Chen, Duan. (2014) botox.
  • Intervju
    Chen, Duan. (2014) Skal teste Botox i kampen mot kreft.
  • Intervju
    Chen, Duan. (2014) Botox may have cancer fighting role.
  • Intervju
    Chen, Duan. (2014) Treating cancer with botox.
  • Intervju
    Chen, Duan. (2014) Las inyecciones de bótox podrían servir como tratamiento del cáncer de estómago.
  • Intervju
    Chen, Duan. (2014) Botox injections may halt cancer growth.
  • Intervju
    Chen, Duan. (2014) Skal teste Botox mot kreft.
  • Intervju
    Chen, Duan. (2014) Skal teste Botox i kampen mot kreft.
  • Intervju
    Chen, Duan. (2014) Botox brukes mot langt mer enn rynker.
  • Intervju
    Chen, Duan. (2014) Behandler kreft med botox.
  • Intervju
    Chen, Duan. (2014) Treating cancer with Botox.
  • Intervju
    Chen, Duan. (2014) Botox may slow tumor growth in stomach cancer.
  • Intervju
    Chen, Duan. (2014) NTNU-forskning vekker internasjonal oppsikt.
  • Intervju
    Chen, Duan. (2014) Le Botox freine la progression du cancer de l'estomac.
  • Intervju
    Chen, Duan. (2014) Botox May Slow Tumor Growth In Stomach Cancer.
  • Konferanseposter
    Johannessen, Helene; Olsen, Magnus Kringstad; Cassie, Nikki; Barrett, Perry; Rehfeld, Jens F.; Holst, Jens J.; Kulseng, Bård Eirik; Zhao, Chun-Mei; Chen, Duan. (2014) Preclinical Trial of Gastric Injection of Botulinum Toxin Type A as Weight-Loss-Surgery. Digestive Disease Week 2014
  • Konferanseforedrag
    Zhao, Chun-Mei; Mark, Kidd,; Chen, Duan. (2014) Triple Roles of Autophagy in Cytoprotection, Cell Death and Tumorigenesis With Special Reference to Gastric ECL Cells. DDW 2014
  • Konferanseposter
    Zhao, Chun-Mei; Yoku, Hayakawa; Westphalen,, Christoph B; Muthupalani,, Sureshkumar; Johannessen, Helene; Andersen, Gøran Troseth; Fox,, James G; Wang,, Timothy C.; Chen, Duan. (2014) Preclinical Trial of Botulinum Toxin Type a Injection in the Treatment of Gastric Cancer. DDW 2014
  • Intervju
    Chen, Duan. (2014) Botox injections may halt cancer growth: Research.
  • Intervju
    Chen, Duan. (2014) Le BOTOX pour stopper le cancer de l'estomac – Science Translational Medicine -.
  • Intervju
    Chen, Duan. (2014) Treating gastric cancer -- with Botox.
  • Intervju
    Chen, Duan. (2014) Studio: botulino in aiuto contro il tumore allo stomaco.
  • Intervju
    Chen, Duan. (2014) Ботокс поможет победить рак желудка.
  • Intervju
    Chen, Duan. (2014) Magenkrebs: Nervengift könnte Wachstum aufhalten.
  • Intervju
    Chen, Duan. (2014) Botox testas mot cancer.
  • Intervju
    Chen, Duan. (2014) Cáncer gástrico: El Botox podría ser una alternativa a la quimioterapia?.
  • Intervju
    Chen, Duan. (2014) Botox may slow tumour growth in stomach.
  • Intervju
    Chen, Duan. (2014) Botox could halt stomach cancer.
  • Intervju
    Chen, Duan. (2014) Botox Injections Could Be Used To Treat Stomach Cancer, Experts Say.
  • Intervju
    Chen, Duan. (2014) Botox mot kreft.
  • Intervju
    Chen, Duan. (2014) Botox may slow tumour growth in stomach.
  • Intervju
    Chen, Duan. (2014) Study: Botox Could Prevent Spread of Gastric Cancer -.
  • Intervju
    Chen, Duan. (2014) Botox 'highly effective' treatment of gastric cancer.

2013

  • Konferanseforedrag
    Johannessen, Helene; Kodama, Yosuke; Chen, Duan; Zhao, Chun-Mei. (2013) WP7: Vagal involvement in brain signaling and response to food and gut hormones. Full4Health Project Meeting
  • Konferanseforedrag
    Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Lyle, Robert; Bettencourt, Paulo; Miroljub, Popovic; Witter, Menno; Barrett, Perry. (2013) Role of the vagus nerve in the gut-brain axis revealed by stimulation and blockade of the gastric vagus nerve. Digestive Disease Week 2013
  • Konferanseforedrag
    Øverby, Anders; Zhao, Chun-Mei; Yosuke, Kodama; M, Bones Atle; Chen, Duan. (2013) Naturally Occurring Isothiocyanates Inhibit Gastric Cancer Cell Growth by Disruption of Microtubules. 15th Taithotoyama International Symposium on Gastroenterology.
  • Konferanseforedrag
    Chen, Duan; Yosuke, Kodama; Zhao, Chun-Mei; Sureshkuma, Muthupalani; Yoku, Hayakawa; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne; Beisvag, Vidar; Johannessen, Helene. (2013) Denervation suppresses Gastric Tumorigenesis. 15th Taithotoyama International Symposium on Gastroenterology.
  • Konferanseforedrag
    Chen, Duan. (2013) Novel Strategy for Control of Gastric Cancer: Surgical or Pharmocological Denervation. The 4th JCA-AACR Special Joint Confence--The Latest Advances in Gastric Cancer Research: From Basic Science to Therapeutics
  • Konferanseforedrag
    Okabe, Susumu; Okamoto, T; Matsui, Hiroshi; Zhao, Chun-Mei; Chen, Duan. (2013) A potential New Therapy for Gastric Cancer: Acetic Acid Induces Cancer Cell Death. 15th Taithotoyama International Symposium on Gastroenterology.
  • Konferanseforedrag
    Zhao, Chun-Mei; Chen, Duan. (2013) The morphologic pathway of exocytosis, crinophagy and autophagy in gastric ECL cells and gastric carcinoids (ECLomas). 15th Taithotoyama International Symposium on Gastroenterology
  • Konferanseposter
    Kodama, Yosuke; Zhao, Chun-Mei; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, Richard A.; Sandvik, Arne; Beisvag, Vidar; Johannessen, Helene; Hayakawa, Yoku; Tomita, Hiroyuki. (2013) Denervation Suppresses Gastric Cancer Initiation and Progression Through Inhibition of the Cancer Niche. Digestive Disease Week 2013
  • Konferanseforedrag
    Johannessen, Helene; Revesz, David; Kodama, Yosuke; Cassie, Nikki; Skibicka, Karolina P.; Lyle, Robert; Bettencourt, Girao Paulo Jorge; Popovic, Miroljub; Witter, Menno; Barrett, Perry. (2013) Role of the vagus nerve in the gut-brain axis revealed by stimulation and blockade of the gastric vagus nerve. The 1st National PhD Conference in Neuroscience
  • Konferanseforedrag
    Oostindjer, Marije; Chen, Duan. (2013) Does a healthy brain prevent cancer, The role of the brain-gut axis. How can we approach consensus on the healthiness of red meat?
  • Konferanseposter
    Røe, Oluf Dimitri; Chen, Duan; Chen, Wu; Chen, Yijiang; Zhi, Xiaofei. (2013) DNA repair suppression and effect of cisplatin in mesothelioma and lung cancer cell lines. ASCO 2013

2012

  • Konferanseforedrag
    Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Chen, Duan. (2012) Potential role of the afferent and efferent vagus nerve in control of eating behavior: new target for obesity therapy. A Satellite Symposium of IUPHAR, GI section, International Ulcer Week 2012
  • Konferanseforedrag
    Zhao, Chun-Mei; Chen, Duan. (2012) Life cycle of the secretory organelles and signal pathways in gastric ECL cells. A Satellite Symposium of IUPHAR, GI section, International Ulcer Week 2012
  • Konferanseforedrag
    Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Friedman, RA; Sandvik, AK.; Fox, JG; Wang, TC; Chen, Duan. (2012) Potential role of the vagus nerve in gastric tumorigenesis: new target fro cancer therapy. A Satellite Symposium of IUPHAR, GI section, International Ulcer Week
  • Konferanseforedrag
    Chen, Duan; Zhao, Chun-Mei. (2012) Genetic dissection of the mechnism underlying gastric acid secretion. A Satellite Symposium of IUPHAR, GI section,

2011

  • Konferanseforedrag
    Johannessen, Helene; Kodama, Yosuke; Zhao, Chun-Mei; Chen, Duan. (2011) WP7: Vagal involvement in brain signaling and response to food and gut hormones. Full4Health Project Meeting
  • Konferanseforedrag
    Vigen, Reidar Alexander; Kidd, Mark; Modlin, Irvin; Chen, Duan; Zhao, Chun-Mei. (2011) Ultrastructral Evidence for a Mechanism of ECL Cell Transformation to Gastric Carcinoid in Mastomys Involving Impairment of Autophagy and Loss of Gastrin Control. DDW 2011
  • Konferanseposter
    Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Sandvik, Arne K.; Chen, Duan. (2011) Stomach-Bone Axis: Possible Involvement of Signaling Pathways and Vitamin D Governing Bone Metabolism. DDW 2011
  • Konferanseposter
    Kodama,, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Flatberg, Arnar; Sandvik, Arne K.; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2011) Evidence for Mechanism of Vagal Innervation in Gastric Cancer Initiation Involving Signaling Pathways Governing Stem Cells in Mice. DDW 2011
  • Konferanseposter
    Kodama,, Yosuke; Johannessen, Helene; Furnes, Marianne Waldum; Zhao, Chun-Mei; Kulseng, Baard; Chen, Duan. (2011) Energy Metabolism Following High-Fat Diet and Bariatric Surgeries (Gastric Bypass, Sleeve Gastrectomy, Duodenal Switch and Ileum Transposition) in Rats. DDW 2011
  • Konferanseposter
    Johannessen, Helene; Kodama, Yosuke; Cao, HaiLong; Kulseng, Baard; Zhao, Chun-Mei; Chen, Duan. (2011) Eating Behavior in Rats Subjected to Ileum Transposition and Sleeve Gastrectomy. DDW 2011

2010

  • Konferanseforedrag
    Chen, Duan. (2010) GI pharmacology: the importance of bench-to-bedside-and-back concept. The 16th World Congress on Basic and Clinical Pharmacology
  • Konferanseforedrag
    Kodama, Yosuke; Zhao, Chun-Mei; Quante, Michael; Muthupalani, Sureshkumar; Fox, James G.; Wang, Timothy C.; Chen, Duan. (2010) Truncal vagotomy inhibited gastric cancer initiation in the INS-GAS mouse model. DDW 2010
  • Konferanseforedrag
    Kodama, Yosuke; Zhao, Chun-Mei; Kulseng, Baad; Chen, Duan. (2010) Eating Behavior in Rats Subject to Vagotomy, Sleeve Gastrectomy and Duodenal Switch. DDW 2010
  • Konferanseposter
    Zhao, Chun-Mei; Kodama, Yosuke; Flatberg, Arnar; Anderssen, Endre; Sandvik, Arne Kristian; Chen, Duan. (2010) Gastric ECL cells, rather than gastric acid, play an important role in gut-bone axis. DDW 2010

2009

  • Konferanseforedrag
    Zhao, Chun-Mei; Friis-Hansen, L; Wang, Timothy C.; Chen, Duan. (2009) Roles of helicobacter pylori(H.pylori), gastrin and gastric acid in gastric carcinogenesis. Studies using gastrin gene engineered mouse model. 13th International Conference on Gastrointestinal Research
  • Konferanseposter
    Zhao, Chun-Mei; Andersen, Endre; Chen, Duan. (2009) Gene Expression and Pathway Analysis of Mouse Stomach: Gastric ECL Cells May Produce Vitamin D. DDW 2009
  • Konferanseforedrag
    Zhao, Chun-Mei; Friis-Hansen, L; Wang, Timothy C.; Chen, Duan. (2009) Roles of helicobacter pylori(H.pylori), gastrin and gastric acid in gastric carcinogenesis. Studies using gastrin gene engineered mouse model. 13th international conference on gastrointestinal research/13th international conference on ulcer research
  • Konferanseforedrag
    Chen, Duan; Furnes, Marianne; Zhao, Chun-Mei. (2009) Translational research on obesity: from bedside to bench. 13th internatuonal conference on gastrointestinal research /13th international conference on ulcer research
  • Konferanseforedrag
    Arum, Carl-Jørgen; Anderssen, Endre; Zhao, Chun-Mei; Chen, Duan. (2009) Gene expression profiles of bladder cancer: Comparison between rat bladder cancer model and human bladder cancer patients. Bioinformatics Forum for Young Scientists
  • Konferanseforedrag
    Song, Zhigang; Bhagat, Govind; Baik, Gwang Ho; Gordon, Shanisha A.; Mitchell, Anthony; Zhao, Chun-Mei; Chen, Duan; Dannenberg, Andrew; Wang, Timothy C.. (2009) Development of a Mouse Model of Inflammation-Dependent Pancreatic Cancer. DDW 2009
  • Konferanseforedrag
    Zhao, Chun-Mei; Chen, Duan. (2009) Differentiation of Gastric ECL Cells in CCK 1+2 Receptor Double Knockout Mice. DDW 2009

2008

  • Konferanseforedrag
    Chen, Duan. (2008) Genetic and environmental factors in stomach cancer gastrin, H. Pylori and snus. Tirsdagsmøte for DMF, NTNU og St. Olavs Hospital
  • Konferanseforedrag
    Arum, Carl-Jørgen; Anderssen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2008) Vertsimmunrespons til urotelialkreftcelleinvasjon: DNA mikroarray og pathway analyse av ortotopisk rotteblærekreftmodell. Kirurgisk Høstmøte 2008

2007

  • Intervju
    Chen, Duan. (2007) Snus kan føre til magekreft.
  • Konferanseposter
    Zhao, Chun-Mei; Furnes, Marianne Waldum; Stenström, Björn Stenström; Tømmerås, Karin; Chen, Duan. (2007) Reduced food intake but increased appetite in rats subjected to gastrectomy. DDW 2007
  • Konferanseposter
    Zhao, Chun-Mei; Marianne, F; Tømmerås, Karin; Skoglund, Trine; Chen, Duan. (2007) Localization of Obestatin and Ghrelin in Gastrointerological Tract and Pancreas of Rats. Digestive Disease Week 2007
  • Konferanseforedrag
    Gederaas, Odrun Arna; Randeberg, Lise Lyngsnes; Larsen, Eivind La Puebla; Hjelde, Astrid; Arum, Carl-Jørgen; Brunsvik, Anders; Zhao, Chun-Mei; Chen, Duan; Svaasand, Lars O.; Krokan, Hans Einar. (2007) Effects of hexyl 5-aminolevulinate and light in a rat bladder cancer model. 12 th Congress, European Society for Photobiology, Bath
  • Konferanseforedrag
    Gederaas, Odrun Arna; Larsen, Eivind La Puebla; Randeberg, Lise Lyngsnes; Arum, Carl-Jørgen; Hjelde, Astrid; Zhao, Chun-Mei; Chen, Duan; Krokan, Hans Einar; Svaasand, Lars O.. (2007) 5-ALA-based photodynamic therapy in an experimental bladder tumour model. Forskningsseminar, Lunds Universitets Medisinska Lasercentrum
  • Konferanseposter
    Zhao, Chun-Mei; Karlsson, Bjørn; Chen, Duan. (2007) Swedish smokeless tobacco (snus) accelerates gastric cancer in a Helicobacter pylori mouse model. DDW 2007
  • Konferanseforedrag
    Chen, Duan. (2007) Mechanism of gastric acid secretion: history and state-of-the art. Doshisha School of Pharmacy
  • Konferanseforedrag
    Chen, Duan. (2007) Mechanism of gastric acid secretion: known and unknown pathways revealed in a series of knockout mouse strains. Kyoto Pharmaceutical University and NTNU
  • Konferanseforedrag
    Arum, Carl-Jørgen; Andersen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2007) Gene expression profiling and pathway analysis of orthotopic rat bladder cancer model. 41 st Annual Meeting of the European Society for Clinical Investigation
  • Konferanseforedrag
    Arum, Carl-Jørgen; Andersen, Endre; Tømmerås, Karin; Zhao, Chun-Mei; Chen, Duan. (2007) Pathway analyse av orthotopisk rotteblære kreftmodell og human blære kreft. Kirurgisk Høstmøte 2007

2006

  • Konferanseposter
    Zhao, Chun-Mei; Chen, Duan; Stenström, Björn; Furnes, Marianne; Tømmerås, Karin; Arum, Carl-Jørgen; Syvenssen, Unni. (2006) Mechanisms of body weight loss after gastric bypass surgery in rats. DDW
  • Konferanseposter
    Helge, Eli; Zhao, Chun-Mei; Follestad, Turid; Ijssel, Paul van den; Eijk, Paul p; Ylstra, Bauke; Falkmer, Ursula; Chen, Duan. (2006) Gene expression profile of stomach in response to food intake in mice. Digestive Disease Week
  • Konferanseposter
    Zhao, Chun-Mei; Chen, Duan. (2006) Somatostatin receptor type 2 knockout mice display inhibitory effect of galanin on ECL cells but enhanced action of gastrin on parietal cells. Ammerican Gastroenterology Association (DDW)
  • Konferanseforedrag
    Zhao, Chun-Mei; Chen, Duan; Helge, Eli. (2006) The transcriptomes of stomach in response to food intake in mice. Midt-Norsk Forskningforum i Gastroenterologi. Meråker, Norge
  • Konferanseforedrag
    Zhao, Chun-Mei; Chen, Duan. (2006) Somatostatin receptor type 2 knockout mice display inhibitory effect of galanin on ECL cells but enhanced action of gastrin on parietal cells. Midt-Norsk Forskningforum i Gastroenterologi.

2005

  • Konferanseforedrag
    Arum, Carl Jørgen; Tømmerås, Karin; Gederaas, Odrun Arna; Anderssen, Endre; Zhao, Chun-Mei; Chen, Duan. (2005) Gene expression profiling of orthotopic rat bladder cancer model. International symposium
  • Konferanseforedrag
    Tømmerås, Karin; Furnes, Marianne Waldum; Syversen, Unni; Dickson, S; Chen, Duan. (2005) Mechanisms of body weight loss after gastric bypass surgery. International Symposium on Translational Research
  • Konferanseforedrag
    Martinez, V; Piqueras, L; Taché, Y; Chen, Duan. (2005) Somatostatin receptor type 2 knockout mice display inhibitory effect of galanin on ECL cells but enhanced action of gastrin on parietal cells. International Symposium on Translational Research
  • Konferanseforedrag
    Håkanson, R; Chen, Duan. (2005) Intracellular traffic of secretory organelles in ECL cells of stomach. BioScience 2005 - SECC
  • Konferanseforedrag
    Furnes, Marianne Waldum; Karlsson, Bjørn; Chen, Duan. (2005) Comprehensive monitoring of food intake of rats subjected to gastric bypass. International Symposium on Translational Research
  • Konferanseforedrag
    Tømmerås, Karin; Syversen, Unni; Chen, Duan. (2005) Long-term effect of gastric bypass surgery on body composition and bone in rats. Midt-Norsk Forskningsforum
  • Konferanseforedrag
    Vigen, RA; Arum, Carl-Jørgen; Karlsson, Bjørn; Chen, Duan. (2005) A unique model for studying the physiology of gastrin: gastrocystoplasty. International Symposium on Translational Research
  • Konferanseforedrag
    Larimar, E; Helge, E; Danielsen, S; Marthinsen, A-B; Falkmer, Ursula; Chen, Duan. (2005) Inhibition of bladder cancer rat cell line growth by green tea compound polyphenol epigallocatechinin-3-gallat and radiation. International Symposium on Translational Research
  • Konferanseforedrag
    Karlsson, Bjørn; Tømmerås, Karin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan. (2005) Long-term effect of gastric bypass surgery on body composition and bone in rats. Midt-Norsk forskningsforum

2003

  • Konferanseforedrag
    Okabe, S.; Aihara, T.; Chen, Duan. (2003) Role of M3 receptor muscarinic receptor in gastric acid secretion and gastric mucosal integrity. Studies with M3-receptor knockout micd. Proceedings of 11th International cenference on ulcer research
  • Konferanseforedrag
    Chen, Duan; Zhao, C.M.; Håkanson, R; Samuelson, L.C.; Rehfeld, Jens F.; Friis-Hansen, L. (2003) Regulatory pathways of gastric acid secretion are altered in gastrin- and cholecytokinin-deficient mice. Midt-Norsk Forskningsforum i Gastroenterologi
  • Konferanseforedrag
    Martinsen, Tom Christian; Bakke, I; Chen, Duan; Aamo, T; Zahlsen, Kolbjørn; Waldum, Helge. (2003) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPARa receptors. Midt-Norsk Forskningsforum i Gastroenterologi
  • Konferanseforedrag
    Chen, Duan; Wang, X.; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2003) Chronic Helicobacter pylori infection may result in gastric cancer in hypergastrinemic mice but not in gastrin-deficient mice. Proceedings of International Conference on Applied Genomics - 9th ESACP/16th ISDQP Meeting (ICAG-2003) Focus on: Translational Genomics in Oncology
  • Konferanseforedrag
    Chen, Duan; Zhao, C.M.; Wang, X.; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2003) Does gastrin play any role in development of gastric cancer or duodenal ulcer after chronic Helicobacter pylori infection?. Proceedings of 11th International conference on ulcer research
  • Konferanseforedrag
    Chen, Duan. (2003) ECL-cell histamine: up-to-date. 7th Japanese Histamine Research Symposium
  • Konferanseforedrag
    Martinsen, Tom Christian; Bakke, I; Chen, Duan; Waldum, Helge. (2003) Mekanismen for fibrat-indusert hypergastrinemi. Norsk gastroenterologisk forenings 30. årsmøte
  • Konferanseposter
    Chen, Duan; Zhao, Chun-Mei; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2003) Chronic Helicobacter pylori infection may result in gastric cancer in hypergastrinemic mice but not in gastrin-deficient mice. International Conference on Applied Genomics
  • Konferanseposter
    Chen, Duan; Zhao, Chun-Mei; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2003) Does gastrin play any role in development of gastric cancer or duodenal ulcer after chronic Helicobacter pylori infection?. 11th International Conference on ulcer research
  • Foredrag
    Chen, Duan; Zhao, Chun-Mei; Håkanson, Rolf; Samuelson, L.C.; Rehfeld, Jens F.; Friis-Hansen, L. (2003) Regulatory pathways of gastric acid secretion are altered in gastrin- and cholecytokinin-deficient mice. Midt-Norsk Forskningsforum i gastroenterologi
  • Aviskronikk
    Cui, Guanglin; Koh, Theodore J.; Chen, Duan; Zhao, Chun-Mei; Dockray, G.J.; Varro, A.M.; Fox, J; Wang, T. (2003) Overexpression of glycine-extended gastrin maintains acid secretion and prevents the development of preneoplasia in the stomach via reducing parietal cell lost in transgenic mice.

2002

  • Konferanseforedrag
    Chen, Duan; Zhao, Chun-Mei; Wang, X; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2002) Disparate effects of chronic Helicobacter pylori infection on parietal cells and ECL cells in wild-type vs gastrin-deficient mice. 18th UICC International Cancer Congress
  • Konferanseforedrag
    Chen, Duan; Zhao, Chun-Mei; Wang, X; Friis-Hansen, L; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2002) Host gastrin may determine who will get gastric cancer and who will develop duodenal ulcer after chronic Helicobacter pylori infection. Regpep 2002
  • Konferanseforedrag
    Zhao, Chun-Mei; Wang, Timothy C.; Kopin, Alan S.; Håkanson, Rolf; Chen, Duan. (2002) Mechanism of ECL-cell tumour formation. Studies in rats and transgenic mice. 18th UICC International Cancer Congress
  • Konferanseforedrag
    Kopin, Alan S.; McBride, E.W.; Ren, Y.; Chen, Duan; Beinborn, M. (2002) A rapid approach to identifying cholecystokinin-2 receptor small molecule ligands with full agonist activity. Regpep 2002
  • Konferanseforedrag
    Chen, Duan; Friis-Hansen, L; Håkanson, R. (2002) Revelation of the complexity of gastric acid secretory mechanism by genetic dissection. BioScience 2005

2001

  • Konferanseforedrag
    Chen, Duan; Zhao, Chun-Mei; Falkmer, Sture Emil; Waldum, Helge. (2001) Ablation of parietal cells is associated with ECL-cell hyperplasia in transgenic mice with a genetically engineered ablation of their parietal cell lineage. Digestive Disease Week
  • Konferanseforedrag
    Chen, Duan; Friis-Hansen, L; Wang, X; Zhao, Chun-Mei; Waldum, Helge; Halgunset, Jostein; Wadstrøm, T. (2001) Different effects of chronic Helicobacter pylori infection on parietal and ECL cells between wild type and gastrin-deficient mice. Digestive Disease Week
  • Konferanseforedrag
    Cui, Guanglin; Syversen, Unni; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge. (2001) Behandling av unge rotter med omeprazol resulterer i redusert beintetthet og redusert vektøkning. Norsk Gastroenterologisk Forenings 28. årsmøte

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