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  1. Ansatte

Språkvelger

English

Ingunn Bakke

Last ned pressefoto
Last ned pressefoto
Foto:

Ingunn Bakke

Førsteamanuensis, Nestleder for utdanning medisinstudiet ved IKOM
Institutt for klinisk og molekylær medisin
Fakultet for medisin og helsevitenskap

ingunn.bakke@ntnu.no
98485755 72825299 Gastrosenteret, Rom 431.03.0, 3. etg nord, Øya, Prinsesse Kristinas gate 1
Google Scholar CAG-IBD Forskningsgruppe IBD
Om Forskning Publikasjoner Undervisning Formidling

Om

Kompetanseord

  • Applied Artificial Intelligence
  • Bildeanalyse
  • Endokrine celler, tarm
  • Epitelceller
  • Histopatologi
  • Inflammasjon
  • Inflammatorisk tarmsykdom
  • Mage-tarmsykdommer / gastrointestinale sykdommer
  • Organoider
  • Patologiske prosesser
  • Translasjonell medisinsk forskning

Forskning

  • Clinical Academic Group - Precision Medicine in Inflammatory Bowel Disease (CAG-IBD)
  • NTNU/St. Olav Hospital IBD forskningsgruppe

Publikasjoner

  • Kronologisk
  • Etter kategori
  • Alle publikasjoner i Nasjonalt vitenarkiv (NVA)

2025

  • Sridhar, Arun; Bakke, Ingunn; Gopalakrishnan, Shreya; Osoble, Nimo Mukhtar Mohamud; Hammarqvist, Emilie Prytz; Pettersen, Henrik Sahlin. (2025) Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids. Scientific Reports
    Vitenskapelig artikkel

2023

  • Walaas, Gunnar Andreas; Gopalakrishnan, Shreya; Bakke, Ingunn; Skovdahl, Helene Kolstad; Flatberg, Arnar; Østvik, Ann Elisabeth. (2023) Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids. Frontiers in Immunology
    Vitenskapelig artikkel
  • Gopalakrishnan, Shreya; Bakke, Ingunn; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Granlund, Atle van Beelen; Sandvik, Arne Kristian. (2023) Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids. Frontiers in Immunology
    Vitenskapelig artikkel

2022

  • Røyset, Elin Synnøve; Pettersen, Henrik Sahlin; Xu, Weili; Larbi, Anis; Sandvik, Arne Kristian; Steigen, Sonja Eriksson. (2022) Deep learning-based image analysis reveals significant differences in the number and distribution of mucosal CD3 and γδ T cells between Crohn's disease and ulcerative colitis. The journal of pathology. Clinical research
    Vitenskapelig artikkel
  • Pettersen, Henrik P Sahlin; Belevich, Ilya; Røyset, Elin Synnøve; Smistad, Erik; Simpson, Melanie Rae; Jokitalo, Eija. (2022) Code-Free Development and Deployment of Deep Segmentation Models for Digital Pathology. Frontiers in Medicine
    Vitenskapelig artikkel
  • Gopalakrishnan, Shreya; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Roseth, Ingrid Aass; Granlund, Atle van Beelen; Østvik, Ann Elisabet. (2022) Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium. Frontiers in Immunology
    Vitenskapelig artikkel
  • Sæterstad, Siri; Østvik, Ann Elisabet; Røyset, Elin Synnøve; Bakke, Ingunn; Sandvik, Arne Kristian; Granlund, Atle van Beelen. (2022) Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease. PLOS ONE
    Vitenskapelig artikkel

2021

  • Bakke, Ingunn; Walaas, Gunnar Andreas; Bruland, Torunn; Røyset, Elin Synnøve; Granlund, Atle van Beelen; Escudero-Hernandez, Celia. (2021) Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis. Journal of gastroenterology
    Vitenskapelig artikkel
  • Vie, Gunnhild Åberge; Grimstad, Hilde; Bakke, Ingunn; Wenzel, Hanne Gro; Standal, Rune; Flatås, Kari. (2021) Utforming av læringsutbytte på emnenivå for profesjonsstudiet i medisin. Norges teknisk-naturvitenskapelige universitet Norges teknisk-naturvitenskapelige universitet
    Rapport
  • Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Bakke, Ingunn; Ginbot, Zekarias. (2021) Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration. Frontiers in Pharmacology
    Vitenskapelig artikkel

2020

  • Bakke, Ingunn; Bruland, Torunn; Eriksen, Kaja Sørgård; Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Thorsvik, Silje. (2020) Differences in expression of PPARγ in small intestine vs. colon impact the effect of 5-aminosalicylates in inflammatory bowel disease. Journal of Crohn`s and Colitis
    Sammendrag/Abstract
  • Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Bruland, Torunn; Røyset, Elin Synnøve. (2020) Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis. Journal of Crohn`s and Colitis
    Sammendrag/Abstract
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Skovdahl, Helene Kolstad; Bakke, Ingunn. (2020) Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease. Journal of Crohn's and Colitis
    Vitenskapelig artikkel
  • Aasarød, Kristin Matre; Waldum, Helge; Stunes, Astrid Kamilla; Sandvik, Arne Kristian; Flatberg, Arnar; Mjønes, Patricia. (2020) Gastric Corpus Mucosal Hyperplasia and Neuroendocrine Cell Hyperplasia, but not Spasmolytic Polypeptide-Expressing Metaplasia, Is Prevented by a Gastrin Receptor Antagonist in H+/K+ATPase Beta Subunit Knockout Mice. International Journal of Molecular Sciences
    Vitenskapelig artikkel

2019

  • Lund, Line Knutsen; Bakke, Ingunn; Reitan, Solveig Merete Klæbo; Vestvik, Vegard; Berthold-Losleben, Mark; Greger, Hanne Klæboe. (2019) Fornyet psykiatriundervisning og praksis ved NTNUs medisinstudium. Profesjonsstudiet i medisin, Fakultet for medisin og helsevitenskap, NTNU Profesjonsstudiet i medisin, Fakultet for medisin og helsevitenskap, NTNU
    Rapport
  • Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Flo, Trude Helen. (2019) Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels. Journal of Pathology
    Vitenskapelig artikkel

2018

  • Thorsvik, Silje; Bakke, Ingunn; Granlund, Atle van Beelen; Røyset, Elin Synnøve; Damås, Jan Kristian; Østvik, Ann Elisabeth. (2018) Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn's disease. Cell and Tissue Research
    Vitenskapelig artikkel
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Bakke, Ingunn; Thorsvik, Silje. (2018) Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology
    Sammendrag/Abstract
  • Vange, Pål; Bruland, Torunn; Munkvold, Bjørn; Røyset, Elin Synnøve; Gleave, Martin E.; Bakke, Ingunn. (2018) Subtle protective roles of clusterin in gastric metaplasia after acute oxyntic atrophy. Cellular and Molecular Gastroenterology and Hepatology (CMGH)
    Vitenskapelig artikkel

2017

  • Vange, Pål; Bruland, Torunn; Doseth, Berit; Fossmark, Reidar; Sousa, Mirta; Beisvag, Vidar. (2017) The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival. PLOS ONE
    Vitenskapelig artikkel

2016

  • Vange, Pål; Bruland, Torunn; Bakke, Ingunn. (2016) Author reply to Letter to the Editor entitled: "Controversial role of the possible oxyntic stem cell marker ASPM in gastric cancer". Journal of Pathology
    Leserinnlegg
  • Skovlund, Eva; Hojem, Thea Sofie Melhuus; Bakke, Ingunn; Janszky, Imre; Marhaug, Gudmund; Skogvoll, Eirik. (2016) Vitenskapelig kompetanse som tråd gjennom profesjonsstudiet i medisin. Det medisinske fakultet Det medisinske fakultet
    Rapport
  • Bhandari, Sabin; Bakke, Ingunn; Kumar, J. Dinesh; Beisvag, Vidar; Sandvik, Arne Kristian; Thommesen, Liv. (2016) Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion. Biochemical and Biophysical Research Communications - BBRC
    Vitenskapelig artikkel

2015

  • Skovdahl, Helene Kolstad; Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Bakke, Ingunn; Torp, Sverre Helge. (2015) Expression of CCL20 and its corresponding receptor CCR6 is enhanced in active inflammatory bowel disease, and TLR3 mediates CCL20 expression in colonic epithelial cells. PLOS ONE
    Vitenskapelig artikkel
  • Vange, Pål; Bruland, Torunn; Beisvag, Vidar; Erlandsen, Sten Even; Flatberg, Arnar; Doseth, Berit. (2015) Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker overexpressed in cancer. Journal of Pathology
    Vitenskapelig artikkel

2014

  • Bakke, Ingunn; Mattsson, Erney; Nordrum, Ivar Skjåk; Nylund, Anne; Pukstad, Brita; Reitan, Solveig Merete Klæbo. (2014) En fornyet og fremtidsrettet legeutdanning ved NTNU (Forfatterlisten er alfabetisk). Det medisinske fakultet, DMF Det medisinske fakultet, DMF
    Rapport

2013

  • Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne. (2013) NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells. PLOS ONE
    Vitenskapelig artikkel

2012

  • Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
    Vitenskapelig artikkel
  • Erlandsen, Sten Even; Qvigstad, Gunnar; Fossmark, Reidar; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian. (2012) Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach. Regulatory Peptides
    Vitenskapelig artikkel
  • Fjeldbo, Christina Sæten; Bakke, Ingunn; Erlandsen, Sten Even; Holmseth, Jannicke; Lægreid, Astrid; Sandvik, Arne Kristian. (2012) Gastrin upregulates the pro-survival factor secretory clusterin (sCLU) in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel

2011

  • Gustafsson, Björn; Bakke, Ingunn; Hauso, Øyvind; Kidd, Mark; Modlin, Irvin M; Fossmark, Reidar. (2011) Parietal cell activation by arborization of ECL cell cytoplasmic projections is likely the mechanism for histamine induced secretion of hydrochloric acid. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel

2009

  • Waldum, Helge; Kleveland, Per Martin; Brenna, Eiliv; Bakke, Ingunn; Qvigstad, Gunnar; Martinsen, Tom Christian. (2009) Interactions between gastric acid secretagogues and the localization of the gastrin receptor. Scandinavian Journal of Gastroenterology
    Vitenskapelig oversiktsartikkel/review

2006

  • Waldum, Helge; Kleveland, Per Martin; Sandvik, Arne Kristian; Brenna, Eiliv; Bakke, Ingunn. (2006) Gastrin and cell proliferation.
    Vitenskapelig Kapittel/Artikkel/Konferanseartikkel

2005

  • Gustafsson, Bjørn; Tømmerås, Karin; Nordrum, Ivar Skjåk; Loennechen, Jan Pål; Brunsvik, Anders; Solligård, Erik. (2005) Long-term serotonin administration induces heart valve disease in rats. Circulation
    Vitenskapelig artikkel
  • Martinsen, Tom Christian; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian; Zahlsen, Kolbjørn; Aamo, T.. (2005) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alfa. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel

2004

  • Waldum, Helge; Fossmark, R; Bakke, Ingunn; Martinsen, Tom Christian; Qvigstad, G. (2004) Hypergastrinemia in animals and man: Causes and consequences. Scandinavian Journal of Gastroenterology
    Vitenskapelig oversiktsartikkel/review

2003

  • Syversen, Unni; Bakke, Ingunn; Aune, Guro; Thommesen, Liv. (2003) PPAR-alpha agonists increase bone mineral density in female rats. Journal of Bone and Mineral Research
    Sammendrag/Abstract
  • Yadetie, Fekadu; Lægreid, Astrid; Bakke, Ingunn; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-{alpha} agonist ciprofibrate. Physiological Genomics
    Vitenskapelig artikkel

2002

  • Bakke, Ingunn; Hammer, Tommy Arild; Sandvik, Arne Kristian; Waldum, Helge. (2002) PPAR alpha stimulates the rat gastrin-producing cell. Molecular and Cellular Endocrinology
    Vitenskapelig artikkel
  • Waldum, Helge; Kleveland, Per Martin; Sandvik, Arne Kristian; Brenna, Eiliv; Syversen, Unni; Bakke, Ingunn. (2002) The cellular localization of the cholecystokinin 2 (gastrin) receptor in the stomach. Pharmacology and Toxicology
    Vitenskapelig artikkel
  • Tømmerås, Karin; Bakke, Ingunn; Sandvik, Arne Kristian; Larsson, Erik; Waldum, Helge. (2002) Rat parietal cell express CCK-2 receptor mRNA: gene expression analysis of single cells isolated by laser-assisted microdissection. Biochemical and Biophysical Research Communications - BBRC
    Vitenskapelig artikkel

2001

  • Waldum, Helge; Bakke, Ingunn; Torp, Sverre Helge; Qvigstad, G; Brenna, Eiliv; Sandvik, Arne Kristian. (2001) Effects of the peroxisome proliferator ciprofibrate and the somatostatin analogue octreotide alone or in combination on the rat liver. Recent Advances and Research Updates
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Bakke, Ingunn; Tostrup-Skogaker, Nan; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research
    Vitenskapelig artikkel
  • Sandvik, Arne Kristian; Cui, Guanglin; Bakke, Ingunn; Waldum, Helge. (2001) PACAP stimulates gastric acid secretion in the rat by inducing histamine release. American Journal of Physiology
    Vitenskapelig artikkel
  • Reseland, Janne E.; Syversen, Unni; Bakke, Ingunn; Qvigstad, G; Eide, Liv G; Hjertner, ¯yvind. (2001) Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization. Journal of Bone and Mineral Research
    Vitenskapelig artikkel
  • Bakke, Ingunn; Qvigstad, G; Sandvik, Arne Kristian; Waldum, Helge. (2001) The CCK-2 receptor is located on the ECL cell, but not on the parietal cell. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel

Tidsskriftspublikasjoner

  • Sridhar, Arun; Bakke, Ingunn; Gopalakrishnan, Shreya; Osoble, Nimo Mukhtar Mohamud; Hammarqvist, Emilie Prytz; Pettersen, Henrik Sahlin. (2025) Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids. Scientific Reports
    Vitenskapelig artikkel
  • Walaas, Gunnar Andreas; Gopalakrishnan, Shreya; Bakke, Ingunn; Skovdahl, Helene Kolstad; Flatberg, Arnar; Østvik, Ann Elisabeth. (2023) Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids. Frontiers in Immunology
    Vitenskapelig artikkel
  • Gopalakrishnan, Shreya; Bakke, Ingunn; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Granlund, Atle van Beelen; Sandvik, Arne Kristian. (2023) Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids. Frontiers in Immunology
    Vitenskapelig artikkel
  • Røyset, Elin Synnøve; Pettersen, Henrik Sahlin; Xu, Weili; Larbi, Anis; Sandvik, Arne Kristian; Steigen, Sonja Eriksson. (2022) Deep learning-based image analysis reveals significant differences in the number and distribution of mucosal CD3 and γδ T cells between Crohn's disease and ulcerative colitis. The journal of pathology. Clinical research
    Vitenskapelig artikkel
  • Pettersen, Henrik P Sahlin; Belevich, Ilya; Røyset, Elin Synnøve; Smistad, Erik; Simpson, Melanie Rae; Jokitalo, Eija. (2022) Code-Free Development and Deployment of Deep Segmentation Models for Digital Pathology. Frontiers in Medicine
    Vitenskapelig artikkel
  • Gopalakrishnan, Shreya; Hansen, Marianne Dore; Skovdahl, Helene Kolstad; Roseth, Ingrid Aass; Granlund, Atle van Beelen; Østvik, Ann Elisabet. (2022) Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium. Frontiers in Immunology
    Vitenskapelig artikkel
  • Sæterstad, Siri; Østvik, Ann Elisabet; Røyset, Elin Synnøve; Bakke, Ingunn; Sandvik, Arne Kristian; Granlund, Atle van Beelen. (2022) Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn's disease. PLOS ONE
    Vitenskapelig artikkel
  • Bakke, Ingunn; Walaas, Gunnar Andreas; Bruland, Torunn; Røyset, Elin Synnøve; Granlund, Atle van Beelen; Escudero-Hernandez, Celia. (2021) Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis. Journal of gastroenterology
    Vitenskapelig artikkel
  • Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Bakke, Ingunn; Ginbot, Zekarias. (2021) Patient derived colonoids as drug testing platforms-Critical importance of oxygen concentration. Frontiers in Pharmacology
    Vitenskapelig artikkel
  • Bakke, Ingunn; Bruland, Torunn; Eriksen, Kaja Sørgård; Skovdahl, Helene Kolstad; Gopalakrishnan, Shreya; Thorsvik, Silje. (2020) Differences in expression of PPARγ in small intestine vs. colon impact the effect of 5-aminosalicylates in inflammatory bowel disease. Journal of Crohn`s and Colitis
    Sammendrag/Abstract
  • Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Bruland, Torunn; Røyset, Elin Synnøve. (2020) Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis. Journal of Crohn`s and Colitis
    Sammendrag/Abstract
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Skovdahl, Helene Kolstad; Bakke, Ingunn. (2020) Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease. Journal of Crohn's and Colitis
    Vitenskapelig artikkel
  • Aasarød, Kristin Matre; Waldum, Helge; Stunes, Astrid Kamilla; Sandvik, Arne Kristian; Flatberg, Arnar; Mjønes, Patricia. (2020) Gastric Corpus Mucosal Hyperplasia and Neuroendocrine Cell Hyperplasia, but not Spasmolytic Polypeptide-Expressing Metaplasia, Is Prevented by a Gastrin Receptor Antagonist in H+/K+ATPase Beta Subunit Knockout Mice. International Journal of Molecular Sciences
    Vitenskapelig artikkel
  • Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Flo, Trude Helen. (2019) Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels. Journal of Pathology
    Vitenskapelig artikkel
  • Thorsvik, Silje; Bakke, Ingunn; Granlund, Atle van Beelen; Røyset, Elin Synnøve; Damås, Jan Kristian; Østvik, Ann Elisabeth. (2018) Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn's disease. Cell and Tissue Research
    Vitenskapelig artikkel
  • Østvik, Ann Elisabet; Svendsen, Tarjei Dahl; Granlund, Atle van Beelen; Doseth, Berit; Bakke, Ingunn; Thorsvik, Silje. (2018) Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology
    Sammendrag/Abstract
  • Vange, Pål; Bruland, Torunn; Munkvold, Bjørn; Røyset, Elin Synnøve; Gleave, Martin E.; Bakke, Ingunn. (2018) Subtle protective roles of clusterin in gastric metaplasia after acute oxyntic atrophy. Cellular and Molecular Gastroenterology and Hepatology (CMGH)
    Vitenskapelig artikkel
  • Vange, Pål; Bruland, Torunn; Doseth, Berit; Fossmark, Reidar; Sousa, Mirta; Beisvag, Vidar. (2017) The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival. PLOS ONE
    Vitenskapelig artikkel
  • Vange, Pål; Bruland, Torunn; Bakke, Ingunn. (2016) Author reply to Letter to the Editor entitled: "Controversial role of the possible oxyntic stem cell marker ASPM in gastric cancer". Journal of Pathology
    Leserinnlegg
  • Bhandari, Sabin; Bakke, Ingunn; Kumar, J. Dinesh; Beisvag, Vidar; Sandvik, Arne Kristian; Thommesen, Liv. (2016) Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion. Biochemical and Biophysical Research Communications - BBRC
    Vitenskapelig artikkel
  • Skovdahl, Helene Kolstad; Granlund, Atle Van Beelen; Østvik, Ann Elisabet; Bruland, Torunn; Bakke, Ingunn; Torp, Sverre Helge. (2015) Expression of CCL20 and its corresponding receptor CCR6 is enhanced in active inflammatory bowel disease, and TLR3 mediates CCL20 expression in colonic epithelial cells. PLOS ONE
    Vitenskapelig artikkel
  • Vange, Pål; Bruland, Torunn; Beisvag, Vidar; Erlandsen, Sten Even; Flatberg, Arnar; Doseth, Berit. (2015) Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a possible gastric stem/progenitor cell marker overexpressed in cancer. Journal of Pathology
    Vitenskapelig artikkel
  • Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne. (2013) NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells. PLOS ONE
    Vitenskapelig artikkel
  • Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
    Vitenskapelig artikkel
  • Erlandsen, Sten Even; Qvigstad, Gunnar; Fossmark, Reidar; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian. (2012) Regulated endocrine-specific protein 18 (RESP18) is localized to and regulated in A-like cells and G-cells in rat stomach. Regulatory Peptides
    Vitenskapelig artikkel
  • Fjeldbo, Christina Sæten; Bakke, Ingunn; Erlandsen, Sten Even; Holmseth, Jannicke; Lægreid, Astrid; Sandvik, Arne Kristian. (2012) Gastrin upregulates the pro-survival factor secretory clusterin (sCLU) in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel
  • Gustafsson, Björn; Bakke, Ingunn; Hauso, Øyvind; Kidd, Mark; Modlin, Irvin M; Fossmark, Reidar. (2011) Parietal cell activation by arborization of ECL cell cytoplasmic projections is likely the mechanism for histamine induced secretion of hydrochloric acid. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel
  • Waldum, Helge; Kleveland, Per Martin; Brenna, Eiliv; Bakke, Ingunn; Qvigstad, Gunnar; Martinsen, Tom Christian. (2009) Interactions between gastric acid secretagogues and the localization of the gastrin receptor. Scandinavian Journal of Gastroenterology
    Vitenskapelig oversiktsartikkel/review
  • Gustafsson, Bjørn; Tømmerås, Karin; Nordrum, Ivar Skjåk; Loennechen, Jan Pål; Brunsvik, Anders; Solligård, Erik. (2005) Long-term serotonin administration induces heart valve disease in rats. Circulation
    Vitenskapelig artikkel
  • Martinsen, Tom Christian; Bakke, Ingunn; Chen, Duan; Sandvik, Arne Kristian; Zahlsen, Kolbjørn; Aamo, T.. (2005) Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alfa. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel
  • Waldum, Helge; Fossmark, R; Bakke, Ingunn; Martinsen, Tom Christian; Qvigstad, G. (2004) Hypergastrinemia in animals and man: Causes and consequences. Scandinavian Journal of Gastroenterology
    Vitenskapelig oversiktsartikkel/review
  • Syversen, Unni; Bakke, Ingunn; Aune, Guro; Thommesen, Liv. (2003) PPAR-alpha agonists increase bone mineral density in female rats. Journal of Bone and Mineral Research
    Sammendrag/Abstract
  • Yadetie, Fekadu; Lægreid, Astrid; Bakke, Ingunn; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge. (2003) Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-{alpha} agonist ciprofibrate. Physiological Genomics
    Vitenskapelig artikkel
  • Bakke, Ingunn; Hammer, Tommy Arild; Sandvik, Arne Kristian; Waldum, Helge. (2002) PPAR alpha stimulates the rat gastrin-producing cell. Molecular and Cellular Endocrinology
    Vitenskapelig artikkel
  • Waldum, Helge; Kleveland, Per Martin; Sandvik, Arne Kristian; Brenna, Eiliv; Syversen, Unni; Bakke, Ingunn. (2002) The cellular localization of the cholecystokinin 2 (gastrin) receptor in the stomach. Pharmacology and Toxicology
    Vitenskapelig artikkel
  • Tømmerås, Karin; Bakke, Ingunn; Sandvik, Arne Kristian; Larsson, Erik; Waldum, Helge. (2002) Rat parietal cell express CCK-2 receptor mRNA: gene expression analysis of single cells isolated by laser-assisted microdissection. Biochemical and Biophysical Research Communications - BBRC
    Vitenskapelig artikkel
  • Waldum, Helge; Bakke, Ingunn; Torp, Sverre Helge; Qvigstad, G; Brenna, Eiliv; Sandvik, Arne Kristian. (2001) Effects of the peroxisome proliferator ciprofibrate and the somatostatin analogue octreotide alone or in combination on the rat liver. Recent Advances and Research Updates
    Vitenskapelig artikkel
  • Zhao, Chun-Mei; Bakke, Ingunn; Tostrup-Skogaker, Nan; Waldum, Helge; Håkanson, Rolf; Chen, Duan. (2001) Functionally impaired, hypertrophic ECL cells accumulate vacuoles and lipofuscin bodies. An ultrastructural study of ECL cells isolated from hypergastrinemic rats. Cell and Tissue Research
    Vitenskapelig artikkel
  • Sandvik, Arne Kristian; Cui, Guanglin; Bakke, Ingunn; Waldum, Helge. (2001) PACAP stimulates gastric acid secretion in the rat by inducing histamine release. American Journal of Physiology
    Vitenskapelig artikkel
  • Reseland, Janne E.; Syversen, Unni; Bakke, Ingunn; Qvigstad, G; Eide, Liv G; Hjertner, ¯yvind. (2001) Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization. Journal of Bone and Mineral Research
    Vitenskapelig artikkel
  • Bakke, Ingunn; Qvigstad, G; Sandvik, Arne Kristian; Waldum, Helge. (2001) The CCK-2 receptor is located on the ECL cell, but not on the parietal cell. Scandinavian Journal of Gastroenterology
    Vitenskapelig artikkel

Del av bok/rapport

  • Waldum, Helge; Kleveland, Per Martin; Sandvik, Arne Kristian; Brenna, Eiliv; Bakke, Ingunn. (2006) Gastrin and cell proliferation.
    Vitenskapelig Kapittel/Artikkel/Konferanseartikkel

Rapport

  • Vie, Gunnhild Åberge; Grimstad, Hilde; Bakke, Ingunn; Wenzel, Hanne Gro; Standal, Rune; Flatås, Kari. (2021) Utforming av læringsutbytte på emnenivå for profesjonsstudiet i medisin. Norges teknisk-naturvitenskapelige universitet Norges teknisk-naturvitenskapelige universitet
    Rapport
  • Lund, Line Knutsen; Bakke, Ingunn; Reitan, Solveig Merete Klæbo; Vestvik, Vegard; Berthold-Losleben, Mark; Greger, Hanne Klæboe. (2019) Fornyet psykiatriundervisning og praksis ved NTNUs medisinstudium. Profesjonsstudiet i medisin, Fakultet for medisin og helsevitenskap, NTNU Profesjonsstudiet i medisin, Fakultet for medisin og helsevitenskap, NTNU
    Rapport
  • Skovlund, Eva; Hojem, Thea Sofie Melhuus; Bakke, Ingunn; Janszky, Imre; Marhaug, Gudmund; Skogvoll, Eirik. (2016) Vitenskapelig kompetanse som tråd gjennom profesjonsstudiet i medisin. Det medisinske fakultet Det medisinske fakultet
    Rapport
  • Bakke, Ingunn; Mattsson, Erney; Nordrum, Ivar Skjåk; Nylund, Anne; Pukstad, Brita; Reitan, Solveig Merete Klæbo. (2014) En fornyet og fremtidsrettet legeutdanning ved NTNU (Forfatterlisten er alfabetisk). Det medisinske fakultet, DMF Det medisinske fakultet, DMF
    Rapport

Undervisning

Emner

  • MD4020 - Medisin - semester 1CD

Formidling

2025

  • Vitenskapelig foredrag
    Walaas, Gunnar Andreas Enerhaug; Sveaas, Silje; Kuraas, Lusie Frostvoll; Sridhar, Arun; Lillebråten, Kari; Fossen, Hanne. (2025) Humoral immune signatures in uninflamed colon mucosa associated with anti-TNF treatment failure in ulcerative colitis. UEG Week , Berlin 2025-10-03 - 2025-10-06
  • Poster
    Walaas, Gunnar Andreas Enerhaug; Sridhar, Arun; Kuraas, Lusie Frostvoll; Sæterstad, Siri; Schioldborg, Amanda Yin; Granlund, Atle van Beelen. (2025) Organoids as translational tools: Patient-matched transcriptomics reveals similarities between in vitro and in vivo epithelial responses in ulcerative colitis. Organoids: modelling organ development and disease in 3D , Heidelberg 2025-10-20 - 2025-10-24
  • Poster
    Sridhar, Arun; Walaas, Gunnar Andreas Enerhaug; Sæterstad, Siri; Myrmehl, Johan Pierre Durand; Cermakova, Romana; Myrseth, Marte Gisvold. (2025) Approved and investigational JAK/TYK2 inhibitors attenuate inflammatory pathways and promote mucosal homeostasis in IBD patient-derived organoids. Organoids: modelling organ development and disease in 3D , Heidelberg 2025-10-21 - 2025-10-24
  • Poster
    Walaas, Gunnar Andreas Enerhaug; Kuraas, Lusie Frostvoll; Ali, Ann-Therese Chattergoon; Christensen, Tone; Beisvag, Vidar; Bruland, Torunn. (2025) Achieving Spatial Transcriptomic Data from Colonic Mucosal Compartments using FFPE Tissue and Laser Capture Microdissection. NBS Contact Meeting 2025 , Røros 2025-01-23 - 2025-01-25
  • Intervju
    Bakke, Ingunn; Høivik, Marte Lie. (2025) Camilla (35) fant løsningen på inflammatorisk tarmsykdom (IBD): –⁠ Jeg var redd for å gå ut. VG+ VG+ [null] 2025-07-21
  • Faglig foredrag
    Sridhar, Arun; Walaas, Gunnar Andreas Enerhaug; Sæterstad, Siri; Hansen, Marianne Dore; Østvik, Ann Elisabeth; Bakke, Ingunn. (2025) Investigating the effects of JAK-inhibitors on inflammatory responses in intestinal epithelial cells using IBD patient-derived colonoids. 60th NBS Contact Meeting 2025-02-23 - 2026-01-26
  • Poster
    Nakstad, Vu To; Sigfúsdóttir, Margrét Sylvía; Chahal, Aman Singh; Haukaas, Tonje Husby; Ringers, Christa; Bwanika, Henri Colyn Harry. (2025) Miniaturization of patient- and stem cell derived organoids – increasing throughput and reproducibility. NBS Contact Meeting , Røros 2025-01-23 - 2025-01-26

2024

  • Poster
    Sridhar, Arun; Bakke, Ingunn; Østvik, Ann Elisabeth; Pettersen, Henrik Sahlin; Bruland, Torunn. (2024) The impact of tofacitinib and budesonide on stemness, cell death, and chemokine release in IBD patient-derived colonoids. UEG Week 2024-10-12 - 2024-10-15

2023

  • Vitenskapelig foredrag
    Walaas, Gunnar Andreas; Gopalakrishnan, Shreya; Bakke, Ingunn; Skovdahl, Helene Kolstad; Flatberg, Arnar; Østvik, Ann Elisabeth. (2023) Fysiologisk hypoksi forbedrer vekst og funksjonell differensiering av humane tarmepitelorganoider. Norsk Gastroenterologisk Forening , Lillehammer 2023-02-09 - 2023-02-11
  • Intervju
    Christos, Evangelou; Bakke, Ingunn. (2023) Whole Slide Image Analysis Using Deep Learning Helps Map Colon Mucosal Immune Cells in Inflammatory Bowel Disease. https://www.pathologynews.com https://www.pathologynews.com [Internet] 2023-01-02

2021

  • Vitenskapelig foredrag
    Bakke, Ingunn; Walaas, Gunnar Andreas; Bruland, Torunn; Røyset, Elin Synnøve; Granlund, Atle van Beelen; Escudero-hernandez, Celia. (2021) Slimhinne og fekal neutrofil gelatinase-assosiert lipocalin (NGAL) som potensiell biomarkør for kollagenøs kolitt. Norsk gastroenterologisk forenings årsmøte , Lillehammer 2021-02-04 -

2020

  • Vitenskapelig foredrag
    Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escudero-Hernandez, Celia; Bruland, Torunn; Røyset, Elin Synnøve. (2020) Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker in collagenous colitis (CC). European Microscopic Colitis Group meeting , Wien 2020-02-15 - 2020-02-15
  • Vitenskapelig foredrag
    Walaas, Gunnar Andreas; Bakke, Ingunn; Granlund, Atle van Beelen; Escuderos-hernandez, celia; Bruland, Torunn; Røyset, Elin Synnøve. (2020) Neutrophil gelatinase-associate lipocalin (NGAL) as biomarker in collagenous colitis. European Crohn's and Colitis organisation congress , Wien 2020-02-12 - 2020-02-15
  • Poster
    Aasarød, Kristin Matre; Waldum, Helge; Stunes, Astrid Kamilla; Sandvik, Arne Kristian; Flatberg, Arnar; Mjønes, Patricia. (2020) Gastric corpus mucosal hyperplasia and neuroendocrine cell hyperplasia, but not spasmolytic polypeptide-expressing metaplasia is prevented by a gastrin-blocker in H+/K+ATPase beta subunit deficient mice. Digestive Disease Week 2020-05-02 - 2020-05-05

2018

  • Poster
    Thorsvik, Silje; Granlund, Atle van Beelen; Svendsen, Tarjei Dahl; Bakke, Ingunn; Røyset, Elin Synnøve; Afroz, Wahida. (2018) Neutrophil Gelatinase-Associated Lipocalin (NGAL) is expressed in regenerative intestinal epithelium and proinflammatory cytokines induce NGAL in human colonoids. Digestive Disease Week (DDW , Washington DC 2018-06-02 -

2016

  • Vitenskapelig foredrag
    Beisvag, Vidar; Bakke, Ingunn; Andersen, Gøran Troseth; Zhao, Chun-Mei; Chen, Duan; Waldum, Helge. (2016) Signet ring cell carcinomas identified as a molecular subtype of gastric cancer. Digestive Disease Week 2016 , San Diego, CA 2016-05-21 - 2016-05-24
  • Vitenskapelig foredrag
    Vange, Pål; Bruland, Torunn; Doseth, Berit; Sousa, Mirta; Sørdal, Øystein Finset; Qvigstad, Gunnar. (2016) The anti-apoptotic factor clusterin is involved in hypergastrinemia-induced remodeling of the gastric oxyntic mucosa. United European Gastroenterology Week 2016 , Wien 2016-10-17 - 2016-10-19

2015

  • Poster
    Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bakke, Ingunn; Østvik, Ann Elisabet. (2015) Fecal Neutrophil Gelatinase Associated Lipocalin as a biomarker for Inflammatory Bowel Disease. AIBD 2015 , Orlando, Florida 2015-12-08 - 2015-12-12
  • Poster
    Granlund, Atle van Beelen; Thorsvik, Silje; Beisvag, Vidar; Flatberg, Arnar; Bakke, Ingunn; Sandvik, Arne Kristian. (2015) Exploring the barrier; RNA sequencing of laser microdissected epithelium from IBD patients. 10th congress of European Crohn's and Colitis Organisation , Barcelona 2015-02-18 - 2015-02-21
  • Poster
    Granlund, Atle van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Bakke, Ingunn; Bruland, Torunn; Sandvik, Arne Kristian. (2015) Antigen presentation activity of the Intestinal Epithelial Cells. AIBD 2015 , Orlando, FL 2015-12-08 - 2015-12-12
  • Vitenskapelig foredrag
    Vange, Pål; Bruland, Torunn; Beisvag, Vidar; Erlandsen, Sten Even; Doseth, Berit; Sandvik, Arne Kristian. (2015) Genome-wide analysis of the oxyntic proliferative isthmus zone reveals ASPM as a putative gastric stem/progenitor cell marker overexpressed in cancer. Digestive Disease Week 2015 , Washington DC 2015-05-16 - 2015-05-19

2014

  • Faglig foredrag
    Bhandari, Sabin; Bakke, Ingunn; Thommesen, Liv; Sandvik, Arne Kristian; Nørsett, Kristin. (2014) Connective tissue growth factor is activated by gastrin and involved in gastrin-induced migration and invasion. 50th NBS Contact Meeting , Røros 2014-01-23 - 2014-01-26
  • Poster
    Vange, Pål; Beisvag, Vidar; Flatberg, Arnar; Afroz, Wahida; Nordrum, Ivar Skjåk; Sørdal, Øystein Finset. (2014) Molecular mechanisms of cellular stress responses in gastric cancer. Digestive Disease Week 2014 , Chicago 2014-05-03 - 2014-05-06

2013

  • Poster
    Vange, Pål; Beisvag, Vidar; Flatberg, Arnar; Rao, Shalini; Sandvik, Arne Kristian; Thommesen, Liv. (2013) Gastric cancer biology – clusterin facilitates the growth promoting effects of gastrin. NBS Contact Meeting 2013 , Lillehammer 2013-01-31 - 2013-02-03
  • Vitenskapelig foredrag
    Bakke, Ingunn. (2013) Gene expression analysis of the proliferative zone in gastric oxyntic mucosa. Tissue sampling by use of laser microdissection. Ukentlig presentasjon av forskningsprosjekter internt ved IKM , Trondheim 2013-01-01 - 2013-12-31
  • Poster
    Rao, Shalini; Selvik, Linn-Karina M.; Nørsett, Kristin Gabestad; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn. (2013) NR4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. Nuclear receptors: Linking molecules, genomes & physiology , Sorrento 2013-09-06 - 2013-09-10
  • Vitenskapelig foredrag
    Vange, Pål; Erlandsen, Sten Even; Flatberg, Arnar; Beisvag, Vidar; Bruland, Torunn; Sandvik, Arne. (2013) Gene expression analysis of the proliferative zone in gastric oxyntic mucosa. Legestudentenes forskningskonferanse (Frampeik) , Oslo 2013-10-18 - 2013-10-20
  • Poster
    Rao, Shalini; Thommesen, Liv; Nørsett, Kristin; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn. (2013) Nr4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. Kontaktmøte Norsk Biokjemisk Selskap , Røros 2013-01-17 - 2013-01-20

2005

  • Poster
    Gustafsson, Bjørn; Bakke, Ingunn; Tømmerås, Karin; Waldum, Helge. (2005) The Enterochromaffin Cell in the Rat Gastrointestinal Tract has a Neuron-like Appearance. Digestive Disease Week , Chicago 2005-05-14 - 2005-05-19

2002

  • Faglig foredrag
    Yadetie, Fekadu; Bakke, Ingunn; Lægreid, Astrid; Kusnierczyk, Waclaw; Komorowski, Jan; Waldum, Helge. (2002) Analysis of effects of the PPAR alpha agonist ciprofibrate on rat hepatic gene expressions using cDNA microarrays. The 7th IUBMB Conference Receptor-ligand Interactions Molecular, Physiological and Pharmacological Aspects , Bergen 2002-05-08 -
  • Poster
    Thommesen, Liv; Slørdahl, Kari; Bakke, Ingunn; Syversen, Unni. (2002) The PPAR-agonist Wyeth 14643 decreases proliferation in the pre-osteoclast cell line RAW 264.7. Norsk Biokjemisk kontaktmøte , Røros 2002-01-25 -
  • Faglig foredrag
    Tømmerås, Karin; Bakke, Ingunn; Sandvik, Arne Kristian; Waldum, Helge. (2002) Påvisning av CCK-2 reseptor mRNA i parietalceller fra rotte ved laser mikrodisseksjon og "nested" RT-PCR. Norsk Gastroenterologisk Forenings 29. årsmøte , Lillehammer 2002-02-10 -

2001

  • Vitenskapelig foredrag
    Waldum, Helge; Martinsen, Tom Christian; Bakke, Ingunn; Sandvik, Arne Kristian. (2001) The gastric releasing effect of PPAR alpha ligands in rats. PPARs: From Basic Science to Clinical Applications , Florence, Italy 2001-04-07 -
  • Vitenskapelig foredrag
    Bakke, Ingunn; Qvigstad, G; Sandvik, Arne Kristian; Waldum, Helge. (2001) Proliferasjonsmarkører trenger ikke alltid å avspeil reell proliferasjon. Norsk Gastroenterologisk Forenings 28. årsmøte , Lillehammer 2001-02-11 -

2000

  • Faglig foredrag
    Bakke, Ingunn; Sandvik, AK; Waldum, Helge. (2000) Peroksisomproliferatorer frigjør gastrin via en mekanisme som er uavhengig av gastrisk pH og somatostatin. Norsk Gastroenterologisk Forenings (NGF) 27. årsmøte , Lillehammer 10-13 februar
  • Faglig foredrag
    Bakke, Ingunn; Qvigstad, G; Sandvik, AK; Waldum, Helge. (2000) Lokalisering av gastrin/CCK-2 reseptoren til ECL celler ved vaskulær perfusjon av isolert rotteventrikkel med fluorescence-merket CCK-8. Norsk Gastroenterologisk Forenings (NGF) 27. årsmøte , Lillehammer 10 - 13 februar

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