Ingrid Eftedal
Førsteamanuensis Institutt for sirkulasjon og bildediagnostikk Fakultet for medisin og helsevitenskap Prinsesse Kristinas gate 3, AHL * 343.03.005
Bakgrunn og aktiviteter
Jeg forsker på hvordan kroppen reagerer på og tilpasser seg dykking.
Jeg er utdannet sivilingeniør i biofysikk og medisinsk teknologi fra NTH, og har en doktorgrad (dr ing) i molekylær genetikk fra samme sted. Tidligere har jeg bla vært post doc ved Ecole supérieure de biotechnologie i Strasbourg, molekylærbiolog ved Rigshospitalet i København, leder for Avdeling for Medisinsk Genetikk ved St Olavs Hospital, og medlem av Den Rettsmedisinske Kommisjon og Preimplantasjonsdiagnostikknemda.
Vitenskapelig, faglig og kunstnerisk arbeid
Viser et utvalg av aktivitet. Se alle publikasjoner i databasen
Tidsskriftspublikasjoner
- (2016) Age, weight and decompression sickness in rats. Archives of Physiology and Biochemistry. vol. 122 (2).
- (2016) Diving into the rat plasma proteome to get to the bottom of decompression sickness. PROTEOMICS - Clinical Applications.
- (2016) Immune and inflammatory responses to freediving calculated from leukocyte gene expression profiles. Physiological Genomics. vol. 48 (11).
- (2015) The aging diver: endothelial biochemistry and its potential implications for cardiovascular health. Diving and Hyperbaric Medicine. vol. 45 (4).
- (2015) Evaluating PAI-1 as a biomarker for stress in diving: human serum total PAI-1 is unaltered after 2 h dry exposures to 280 kPa hyperbaric air. Physiological Reports. vol. 3:e12537 (6).
- (2014) Eccentric exercise 48 h prior to simulated diving has no effect on vascular bubble formation in rats. European Journal of Applied Physiology. vol. 115 (3).
- (2013) Acute and potentially persistent effects of scuba diving on the blood transcriptome of experienced divers. Physiological Genomics. vol. 45 (20).
- (2013) Effects of hyperbaric oxygen preconditioning on cardiac stress markers after simulated diving. Physiological Reports. vol. 1 (6).
- (2013) Exercise-induced myofibrillar disruption with sarcolemmal integrity prior to simulated diving has no effect on vascular bubble formation in rats. European Journal of Applied Physiology. vol. 113 (5).
- (2012) Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional mutlicentre study. European Journal of Clinical Pharmacology. vol. 68 (1).
- (2012) Early genetic responses in rat vascular tissue after simulated diving. Physiological Genomics. vol. 44 (24).
- (2001) Embryonale stamceller og terapeutisk cloning. Tidsskrift for Den norske legeforening. vol. 121.
- (2001) Single intragenic microsatellite preimplantation genetic diagnosis for cystic fibrosis provides positive allele identification of all CFTR genotypes for informative couples. Molecular human reproduction. vol. 7 (3).
- (1996) Human uracil-DNA glycosylase gene : sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1. Genomics. vol. 36.
- (1996) Human uracil-DNA glycosylase gene: sequence organization, methylation pattern, and mapping to chromosome 12q23-q24.1. Biochemical and Biophysical Research Communications - BBRC.
- (1996) Pseudogenes for the human uracil-DNA glycosylase on chromosomes 14 and 16. Biochemical and Biophysical Research Communications - BBRC. vol. 224.
- (1995) Sequence specificity for removal of uracil from U.A pairs and U.G mismatches by uracil-DNA glycosylase from Escherichia coli, and correlation with mutational hotspots. FEBS Letters. vol. 362.
- (1995) Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase. Biochemistry. vol. 34.
- (1993) Consensus sequences for good and poor removal of uracil from double stranded DNA by uracil-DNA glycosylase. Nucleic Acids Research. vol. 21 (9).
- (1993) Low incorporation of dUMP by some thermostable DNA polymerases may limit their use in PCR amplification. Analytical Biochemistry. vol. 211.
Rapport/avhandling
- (1993) Heterogeneity in the incorporation and excision of uracil in DNA. 1993. ISBN 82-7119-591-3. Doktor ingeniøravhandling (1993:12).
- (1989) Automatization of pressure chamber : Monitoring & control of hyperbaric environment for animalresearch. 1989.