Elise Midtbust Sandholm
Om
I have an MSc in Biotechnology and I am currently working as an engineer in May-Britt Tessems ERC project ProstOmics at the Department of Circulation and Medical Imaging, NTNU. Currently, there is a need for reliable clinical tools to distinguish men whose prostate cancer is likely to me aggressive and life threatening, from those who have indolent slow-growing disease. Our goal is to identify biomarkers for improved diagnosis and treatment of prostate cancer patients. To achieve this we combine several layers of omics information on our prostate tissue samples. I am involved in the development and lab work on our unique analytical multi-omics (genomics, transcriptomics, proteomics, metabolomics) protocol. My work mainly focus on HRMAS and MALDI MS imaging to study metabolomics and laser microdissection to study microproteomics. I also work in the histology lab to do embedding, cryosectioning and scanning.
Publikasjoner
2025
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Wess, Maximilian;
Andersen, Maria Karoline;
Midtbust, Elise;
Guillem, Juan Carlos Cabellos;
Viset, Trond;
Størkersen, Øystein.
(2025)
Spatial integration of multi-omics data from serial sections using the novel Multi-Omics Imaging Integration Toolset.
GigaScience
Vitenskapelig artikkel
-
Blilie, Anders;
Giskeødegård, Guro F.;
Nybøen, Åsmund;
Krossa, Sebastian;
Midtbust, Elise;
Gudlaugsson, Einar.
(2025)
Biobanking after Radical Prostatectomy: Comparison of Slice and Punch Protocols.
Biopreservation and Biobanking
Vitenskapelig artikkel
-
Pedersen, Christine Aaserød;
Fleischer, Thomas;
Wess, Maximilian;
Midtbust, Elise;
Andersen, Maria Karoline;
Viset, Trond.
(2025)
DNA methylation in normal-appearing tissue associated with prostate cancer recurrence and metastasis.
Clinical Epigenetics
Vitenskapelig artikkel
2024
-
Wess, Maximilian;
Andersen, Maria Karoline;
Midtbust, Elise;
Guillem, Juan Carlos Cabellos;
Viset, Trond;
Størkersen, Øystein.
(2024)
Spatial Integration of Multi-Omics Data using the novel Multi-Omics Imaging Integration Toolset.
BioRxiv
Vitenskapelig artikkel
-
Andersen, Maria K.;
Krossa, Sebastian;
Midtbust, Elise;
Pedersen, Christine Aaserød;
Wess, Maximilian;
Høiem, Therese Stork.
(2024)
Spatial transcriptomics reveals strong association between SFRP4 and extracellular matrix remodeling in prostate cancer.
Communications Biology
Vitenskapelig artikkel
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Kiviaho, Antti;
Eerola, Sini K.;
Kallio, Heini M.L.;
Andersen, Maria K.;
Hoikka, Miina;
Salonen, Iida.
(2024)
Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer.
Nature Communications
Vitenskapelig artikkel
2023
-
Andersen, Maria Karoline;
Krossa, Sebastian;
Midtbust, Elise;
Pedersen, Christine Aaserød;
Wess, Maximilian;
Høiem, Therese Stork.
(2023)
Spatial transcriptomics reveals strong association between SFRP4 and extracellular matrix remodeling in prostate cancer.
Research Square
Vitenskapelig artikkel
-
Andersen, Maria Karoline;
Giampà , Marco;
Midtbust, Elise;
Høiem, Therese Stork;
Krossa, Sebastian;
Tessem, May-Britt.
(2023)
Sample Preparation for Metabolite Detection in Mass Spectrometry Imaging.
Methods in molecular biology
Vitenskapelig artikkel
2022
-
Krossa, Sebastian;
Andersen, Maria Karoline;
Midtbust, Elise;
Viset, Trond;
Størkersen, Øystein;
Giskeødegård, Guro.
(2022)
Inflammatory chemokines upregulated in the tumor microenvironment of prostate cancer patients experiencing relapse after radical prostatectomy.
European Urology
Sammendrag/Abstract
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Andersen, Maria Karoline;
Krossa, Sebastian;
Midtbust, Elise;
Viset, Trond;
Størkersen, Øystein;
Giskeødegård, Guro F..
(2022)
Multiomics spatial mapping of lipid metabolism in prostate cancer.
European Urology
Sammendrag/Abstract
Tidsskriftspublikasjoner
-
Wess, Maximilian;
Andersen, Maria Karoline;
Midtbust, Elise;
Guillem, Juan Carlos Cabellos;
Viset, Trond;
Størkersen, Øystein.
(2025)
Spatial integration of multi-omics data from serial sections using the novel Multi-Omics Imaging Integration Toolset.
GigaScience
Vitenskapelig artikkel
-
Blilie, Anders;
Giskeødegård, Guro F.;
Nybøen, Åsmund;
Krossa, Sebastian;
Midtbust, Elise;
Gudlaugsson, Einar.
(2025)
Biobanking after Radical Prostatectomy: Comparison of Slice and Punch Protocols.
Biopreservation and Biobanking
Vitenskapelig artikkel
-
Pedersen, Christine Aaserød;
Fleischer, Thomas;
Wess, Maximilian;
Midtbust, Elise;
Andersen, Maria Karoline;
Viset, Trond.
(2025)
DNA methylation in normal-appearing tissue associated with prostate cancer recurrence and metastasis.
Clinical Epigenetics
Vitenskapelig artikkel
-
Wess, Maximilian;
Andersen, Maria Karoline;
Midtbust, Elise;
Guillem, Juan Carlos Cabellos;
Viset, Trond;
Størkersen, Øystein.
(2024)
Spatial Integration of Multi-Omics Data using the novel Multi-Omics Imaging Integration Toolset.
BioRxiv
Vitenskapelig artikkel
-
Andersen, Maria K.;
Krossa, Sebastian;
Midtbust, Elise;
Pedersen, Christine Aaserød;
Wess, Maximilian;
Høiem, Therese Stork.
(2024)
Spatial transcriptomics reveals strong association between SFRP4 and extracellular matrix remodeling in prostate cancer.
Communications Biology
Vitenskapelig artikkel
-
Kiviaho, Antti;
Eerola, Sini K.;
Kallio, Heini M.L.;
Andersen, Maria K.;
Hoikka, Miina;
Salonen, Iida.
(2024)
Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer.
Nature Communications
Vitenskapelig artikkel
-
Andersen, Maria Karoline;
Krossa, Sebastian;
Midtbust, Elise;
Pedersen, Christine Aaserød;
Wess, Maximilian;
Høiem, Therese Stork.
(2023)
Spatial transcriptomics reveals strong association between SFRP4 and extracellular matrix remodeling in prostate cancer.
Research Square
Vitenskapelig artikkel
-
Andersen, Maria Karoline;
Giampà , Marco;
Midtbust, Elise;
Høiem, Therese Stork;
Krossa, Sebastian;
Tessem, May-Britt.
(2023)
Sample Preparation for Metabolite Detection in Mass Spectrometry Imaging.
Methods in molecular biology
Vitenskapelig artikkel
-
Krossa, Sebastian;
Andersen, Maria Karoline;
Midtbust, Elise;
Viset, Trond;
Størkersen, Øystein;
Giskeødegård, Guro.
(2022)
Inflammatory chemokines upregulated in the tumor microenvironment of prostate cancer patients experiencing relapse after radical prostatectomy.
European Urology
Sammendrag/Abstract
-
Andersen, Maria Karoline;
Krossa, Sebastian;
Midtbust, Elise;
Viset, Trond;
Størkersen, Øystein;
Giskeødegård, Guro F..
(2022)
Multiomics spatial mapping of lipid metabolism in prostate cancer.
European Urology
Sammendrag/Abstract
Formidling
2024
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Vitenskapelig foredragWess, Maximilian; Andersen, Maria Karoline; Midtbust, Elise; Guillem, Juan Carlos Cabellos; Viset, Trond; Størkersen, Øystein. (2024) Integration of Spatial Transcriptomics and Mass Spectrometry Imaging using MIIT. Spatial Omics , Ghent, Belgium 2024-06-13 - 2024-06-14
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Vitenskapelig foredragSharma, Abhibhav; Wess, Maximilian; Andersen, Maria K.; Rye, Morten Beck; Krossa, Sebastian; Midtbust, Elise. (2024) Spatial multi-omics characterization of epithelial glands reveals novel prognostic signatures in prostate cancer. 4th-Nordic Metabolomic Conference 2024 , Turku 2024-08-25 - 2024-08-28
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Vitenskapelig foredragSharma, Abhibhav; Wess, Maximilian; Andersen, Maria K.; Rye, Morten Beck; Krossa, Sebastian; Midtbust, Elise. (2024) Spatial multi-omics characterization of epithelial glands reveals novel prognostic signatures in prostate cancer. 20th Annual International Conference of the Metabolomics Society , Osaka 2024-06-16 - 2024-06-20
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PosterAndersen, Maria Karoline; Krossa, Sebastian; Midtbust, Elise; Pedersen, Christine Aaserød; Wess, Maximilian; Viset, Trond. (2024) Spatial transcriptomics reveals biomarker SFRP4 to be strongly associated with extracellular matrix remodeling in prostate cancer stroma. Spatial Omics , Gent 2024-06-13 - 2024-06-14
2023
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PosterWess, Maximilian; Andersen, Maria Karoline; Midtbust, Elise; Guillem, Juan Carlos Cabellos; Krossa, Sebastian; Rye, Morten Beck. (2023) Registration-based Integration of Spatially Resolved Multi-Omics Data for Prostate Cancer Classification. PRESIMAL Autumn Research School 2023 , Sommarøya, Norway 2023-09-13 - 2023-09-15
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PosterWess, Maximilian; Andersen, Maria Karoline; Midtbust, Elise; Krossa, Sebastian; Rye, Morten Beck; Tessem, May-Britt. (2023) Prostate Cancer Classification using Registration-based Integration of Spatial Multi-Omics Data. NTNU Health , Trondheim, Norway 2023-10-23 - 2023-10-23
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Vitenskapelig foredragWess, Maximilian; Andersen, Maria Karoline; Midtbust, Elise; Krossa, Sebastian; Rye, Morten Beck; Tessem, May-Britt. (2023) Registration-based Integration of Spatial Multi-Omics Data for Prostate Cancer Classification. The 3rd Nordic Metabolomics Conference , Trondheim, Norway 2023-10-18 - 2023-10-20
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Vitenskapelig foredragWess, Maximilian; Andersen, Maria Karoline; Midtbust, Elise; Krossa, Sebastian; Rye, Morten Beck; Tessem, May-Britt. (2023) Integration of Spatial Multi-Omics Data for Prostate Cancer Classification. Regional Mass Spectrometry Imaging Spring Workshop , Uppsala, Swede 2023-03-27 - 2023-03-29
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Vitenskapelig foredragAndersen, Maria Karoline; Midtbust, Elise; Krossa, Sebastian; Viset, Trond; Størkersen, Øystein; Vandenbosch, Michiel. (2023) Spatial multiomics show lipid metabolism alterations in prostate cancer. Regional Mass Spectrometry Imaging Spring Workshop , Uppsala 2023-04-27 - 2023-04-29
2022
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PosterKrossa, Sebastian; Andersen, Maria Karoline; Midtbust, Elise; Wess, Maximilian; Viset, Trond; Størkersen, Øystein. (2022) Inflamed normal appearing glands in the tumor microenvironment of prostate cancer are associated with relapse after radical prostatectomy. The Norwegian Cancer Symposium 2022 2022-09-14 - 2022-09-15
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PosterPedersen, Christine Aaserød; Midtbust, Elise; Krossa, Sebastian; Andersen, Maria Karoline; Viset, Trond; Størkersen, Øystein. (2022) DNA methylation aberrations predicts recurrence both in tumor and normal appearing prostate tissue. European Association of Urology conference 2022 , Amsterdam 2022-06-30 - 2022-07-04
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PosterAndersen, Maria Karoline; Krossa, Sebastian; Midtbust, Elise; Høiem, Therese Stork; Viset, Trond; Størkersen, Øystein. (2022) Multiomics spatial analysis shows lipid metabolism alterations in prostate cancer. 3rd EpiLipidNET Action Meeting , Aveiro 2022-09-21 - 2022-09-23
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Vitenskapelig foredragAndersen, Maria Karoline; Krossa, Sebastian; Midtbust, Elise; Pedersen, Christine Aaserød; Wess, Maximillian; Viset, Trond. (2022) Spatial transcriptomics reveals biomarker SFRP4 to be strongly associated with extracellular matrix remodeling in prostate cancer stroma. The Norwegian Cancer Symposium 2022 , Oslo 2022-09-14 - 2022-09-15
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Vitenskapelig foredragKrossa, Sebastian; Andersen, Maria Karoline; Midtbust, Elise; Wess, Maximilian; Viset, Trond; Størkersen, Øystein. (2022) Inflamed normal appearing glands in the tumor microenvironment of prostate cancer are associated with relapse after radical prostatectomy. NBS Contact Meeting 2022 , Tromsø 2022-02-10 - 2022-02-12
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PosterAndersen, Maria Karoline; Krossa, Sebastian; Midtbust, Elise; Høiem, Therese Stork; Viset, Trond; Størkersen, Øystein. (2022) Multiomics spatial analysis shows lipid metabolism alterations in prostate cancer. Digital Life Conference 2022 , Trondheim 2022-10-20 - 2022-10-21
2021
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Vitenskapelig foredragAndersen, Maria Karoline; Midtbust, Elise; Claes, Britt S.R.; Giampà, Marco; Balluff, Benjamin; Heeren, Ron M.A.. (2021) Vacuum storage at -80°C offers optimal metabolite detection with MALDI-MSI. OurCon2021 , Digitalt 2021-10-12 - 2021-10-13