2026

• Larsen, Helena S.; Sherwood, Anna V.; Rivera-Rangel, Lizandro R.; Ryberg, Line A.; Faller, Paula H.; Thorselius, Caroline E.; Vågbø, Cathrine Broberg; Holmbeck, Kenn; Fernbach, Sonja; Chubanava, Sabina. (2026) Discovery of 5’ NAD capped viral RNAs reveals evolutionary divergent 5’ metabolite capping across hepaciviruses. Nature Communications
  Vitenskapelig artikkel

2025

• Berg, Sigrid Ravn; Brambilla, Alessandro; Hagen, Lars; Sharma, Animesh; Vågbø, Cathrine Broberg; Liabakk, Nina-Beate; Kissova, Miroslava; Barenys, Miquel Arano; Bjørås, Magnar; Torp, Sverre Helge. (2025) Proteomic Analysis Uncovers Enhanced Inflammatory Phenotype and Distinct Metabolic Changes in IDH1 Mutant Glioma Cells. International Journal of Molecular Sciences
  Vitenskapelig artikkel

2024

• Schwarz, Simon D.; Xu, Jianming; Gunasekera, Kapila; Schürmann, David; Vågbø, Cathrine Broberg; Ferrari, Elena; Slupphaug, Geir; Hottiger, Michael O.; Schär, Primo; Steinacher, Roland. (2024) Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation. Nature Communications
  Vitenskapelig artikkel
• Tollersrud, Ole Kristian; Krausz, Máté; Boehler, Vincent; Polyzou, Aikaterini; Seidl, Maximilian; Spahiu, Ambra; Abdullah, Zeinab; Andryka-Cegielski, Katarzyna; Dominick, Felix Immunuel; Huebscher, Katrin. (2024) ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA. Cell reports
  Vitenskapelig artikkel
• Berg, Sigrid Ravn; Demirovic, Aida; Sharma, Animesh; Hagen, Lars; Vågbø, Cathrine Broberg; Zatula, Alexey; Misund, Kristine; Waage, Anders; Slupphaug, Geir. (2024) Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens. Journal of Translational Medicine
  Vitenskapelig artikkel

2023

• Dohnalkova, Michaela; Krasnykov, Kyrylo; Mendel, Mateusz; Li, Lingyun; Panasenko, Olesya; Fleury-Olela, Fabienne; Vågbø, Cathrine Broberg; Homolka, David; Pillai, Ramesh S.. (2023) Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility. Cell reports
  Vitenskapelig artikkel
• Hayran , Abdul Baset ; Liabakk, Nina-Beate; Aas, Per Arne; Kusnierczyk, Anna; Vågbø, Cathrine Broberg; Sarno, Antonio; Iveland, Tobias Solli; Chawla, Konika; Zahn, Astrid; DiNoia, Javier M. (2023) RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel
• Sherwood, Anna V.; Rivera-Rangel, Lizandro R.; Ryberg, Line A.; Larsen, Helena S.; Anker, Klara M.; Costa, Rui; Vågbø, Cathrine Broberg; Jakljevič, Eva; Pham, Long V.; Fernandez-Antunez, Carlota. (2023) Hepatitis C virus RNA is 5′-capped with flavin adenine dinucleotide. Nature
  Vitenskapelig artikkel

2022

• Eftedal, Ingrid; Vågbø, Cathrine Broberg; Lund, Hedda Juni. (2022) Quantification of guanine-derived urinary biomarkers of oxidative stress in saturation divers by LC-MS/MS. Norges teknisk-naturvitenskapelige universitet
  Masteroppgave

2021

• Maddirevula, Sateesh; Alameer, Seham; Ewida, Nour; Sousa, Mirta; Bjørås, Magnar; Vågbø, Cathrine Broberg; Alkuraya, Fowzan S.. (2021) Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant. Human Genetics
  Vitenskapelig artikkel
• Mendel, Mateusz; Delaney, Kamila; Pandey, Radha Raman; Chen, Kuan-Ming; Wenda, Joanna M.; Vågbø, Cathrine Broberg; Steiner, Florian A.; Homolka, David; Pillai, Ramesh S.. (2021) Splice site m⁶A methylation prevents binding of U2AF35 to inhibit RNA splicing. Cell
  Vitenskapelig artikkel
• Steen, Kristian Wollen; Hagen, Lars; Vågbø, Cathrine Broberg; Rabe, Renana; Iveland, Tobias Solli; Aas, Per Arne; Sharma, Animesh; Sporsheim, Bjørnar; Erlandsen, Hilde; Palibrk, Vuk. (2021) ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA. Journal of Translational Medicine
  Vitenskapelig artikkel

2020

• Boeckemeier, L; Kraehenbuehl, R; Keszthelyi, A; Gasasira, MU; Vernon, EG; Beardmore, R; Vågbø, Cathrine Broberg; Chaplin, D; Gollins, S; Krokan, Hans Einar. (2020) Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication. Science Advances
  Vitenskapelig artikkel
• Vågbø, Cathrine Broberg; Slupphaug, Geir. (2020) RNA in DNA repair. DNA Repair
  Vitenskapelig artikkel
• Schär, Primo; Schuermann, David; Schwarz, Simon D.; Grundbacher, Eliane; Hrovat, Alexandra M.; Xu, Jianming; Kusnierczyk, Anna; Vågbø, Cathrine Broberg. (2020) Inducible TDG knockout models to study epigenetic regulation. F1000
  Vitenskapelig artikkel
• Pandey, Radha Raman; Delfino, Elena; Homolka, David; Roithova, Adriana; Chen, Kuan-Ming; Li, Lingyun; Franco, Giulia; Vågbø, Cathrine Broberg; Taillebourg, Emmanuel; Fauvarque, Marie-Odile. (2020) The Mammalian Cap-Specific m⁶Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues. Cell reports
  Vitenskapelig artikkel
• Kong, Xiang Yi; Vik, Erik Sebastian; Nawaz, Meh Sameen; Berges, Natalia; Dahl, Tuva Børresdatter; Vågbø, Cathrine; Suganthan, Rajikala; Segers, Filip; Holm, Sverre; Quiles-Jiménez, Ana M T. (2020) Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel

2019

• Li, Xiang; Zhao, Qiongyi; Wei, Wei; Lin, Quan; Magnan, Christophe; Emami, Michael R; Wearick-Silva, Luis E; Viola, Thiago; Marshall, Paul R; Yin, Jiayu. (2019) The DNA modification N6-methyl-2 '-eoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction. Nature Neuroscience
  Vitenskapelig artikkel
• Prikrylova, Terezia; Robertson, Julia; Ferrucci, Francesca; Konorska, Dorota Joanna; Aanes, Håvard; Manaf, Adeel; Zhang, Beibei; Vågbø, Cathrine Broberg; Kusnierczyk, Anna; Gilljam, Karin Margaretha. (2019) 5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication. Scientific Reports
  Vitenskapelig artikkel
• Monies, Dorota; Vågbø, Cathrine Broberg; Al-Owain, Mohammad; Alhomaidi, Suzan; Alkuraya, Fowzan S.. (2019) Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification. American Journal of Human Genetics
  Vitenskapelig artikkel
• Pinto, Rita; Vågbø, Cathrine Broberg; Jakobsson, Magnus; Yeji, Kim; Baltissen, Marijke P; O'Donohue, Marie-Francoise; Guzman, Ulises H; Malecki, Jedrzej Mieczyslaw; Wu, Jie; Kirpekar, Finn. (2019) The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel

2017

• Ke, Shengdong; Pandya-Jones, Amy; Saito, Yuhki; Fak, John J.; Vågbø, Cathrine Broberg; Geula, Shay; Hanna, Jakob; Black, Douglas L; Darnell, James E.; Darnell, Robert B.. (2017) m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover. Genes & Development
  Vitenskapelig artikkel
• Zatula, Alexey; Dikic, Aida; Mulder, Teska Celine; Sharma, Animesh; Vågbø, Cathrine Broberg; Sousa, Mirta; Waage, Anders; Slupphaug, Geir. (2017) Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia. OncoTarget
  Vitenskapelig artikkel
• Brickner, Joshua R; Soll, Jennifer M; Lombardi, Patrick M; Vågbø, Cathrine Broberg; Mudge, Miranda C; Oyeniran, Clement; Rabe, Renana; Jackson, Jessica; Sullender, Meagan E; Blazosky, Elyse. (2017) A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair. Nature
  Vitenskapelig artikkel
• Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan; Sjaastad, Ivar; Sætrom, Pål; Fedorcsák, Péter; Dahl, John Arne. (2017) Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery
  Vitenskapelig artikkel

2016

• Tekpli, Xavier; Urbanucci, Alfonso; Hashim, Adnan; Vågbø, Cathrine Broberg; Lyle, Robert; Kringen, Marianne K.; Staff, Anne Cathrine; Dybedal, Ingunn; Mills, Ian Geoffrey; Klungland, Arne. (2016) Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells. Epigenetics & Chromatin
  Vitenskapelig artikkel
• Rasmussen, Erik; Vågbø, Cathrine Broberg; Münch, Daniel; Krokan, Hans Einar; Klungland, Arne; Amdam, Gro Vang; Dahl, John Arne. (2016) DNA base modifications in honey bee and fruit fly genomes suggest an active demethylation machinery with species- and tissue-specific turnover rates. Biochemistry and Biophysics Reports
  Vitenskapelig artikkel
• Weber, Alain R.; Krawczyk, Claudia; Robertson, Adam Brian; Kusnierczyk, Anna; Vågbø, Cathrine Broberg; Schürmann, David; Klungland, Arne; Schär, Primo. (2016) Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism. Nature Communications
  Vitenskapelig artikkel

2015

• Bjørge, Monica Dahl; Hildrestrand, Gunn Annette; Scheffler, Katja; Suganthan, Rajikala; Rolseth, Veslemøy; Kusnierczyk, Anna; Rowe, Alexander D.; Vågbø, Cathrine Broberg; Vetlesen, Susanne; Eide, Lars. (2015) Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice. Cell reports
  Vitenskapelig artikkel
• Ke, Shengdong; Alemu, Endalkachew Ashenafi; Mertens, Claudia; Gantman, Emily Conn; Fak, John J.; Mele, Aldo; Haripal, Bhagwattie; Zucker-Scharff, Ilana; Moore, Michael J.; Park, Christopher Y.. (2015) A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes & Development
  Vitenskapelig artikkel

2014

• Zdzalik, Daria; Vågbø, Cathrine Broberg; Kirpekar, F; Davydova, Erna; Puścian, Alicja; Maciejewska, Agnieszka M.; Krokan, Hans Einar; Klungland, Arne; Tudek, Barbara; Van den Born, Erwin. (2014) Protozoan ALKBH8 Oxygenases Display both DNA Repair and tRNA Modification Activities. PLOS ONE
  Vitenskapelig artikkel

2013

• Zheng, Guanqun; Dahl, John Arne; Niu, Yamei; Fedorcsak, Peter; Huang, Chun-Min; Li, Charles J.; Vågbø, Cathrine Broberg; Shi, Yue; Wang, Wen-Ling; Song, Shu-Hui. (2013) ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility. Molecular Cell
  Vitenskapelig artikkel
• Jobert, Laure; Skjeldam, Hanne Kim; Dalhus, Bjørn; Galashevskaya, Anastasia; Vågbø, Cathrine Broberg; Bjørås, Magnar; Nilsen, Hilde. (2013) The human base excision repair enzyme SMUG1 directly interacts with DKC1 and contributes to RNA quality control. Molecular Cell
  Vitenskapelig artikkel
• Galashevskaya, Anastasia; Sarno, Antonio; Vågbø, Cathrine Broberg; Aas, Per Arne; Hagen, Lars; Slupphaug, Geir; Krokan, Hans Einar. (2013) A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported. DNA Repair
  Vitenskapelig artikkel

2012

• Meza, Trine Johansen; Moen, Marivi; Vågbø, Cathrine Broberg; Krokan, Hans Einar; Klungland, Arne; Grini, Paul Eivind; Falnes, Pål. (2012) The DNA dioxygenase ALKBH2 protects Arabidopsis thaliana against methylation damage. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel
• Vågbø, Cathrine Broberg; Svaasand, Eva Kathrine; Aas, Per Arne; Krokan, Hans Einar. (2012) Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response. DNA Repair
  Vitenskapelig artikkel

2011

• Robertson, Adam Brian; Dahl, John Arne; Vågbø, Cathrine Broberg; Tripathi, P; Krokan, Hans Einar; Klungland, Arne. (2011) A novel method for the efficient and selective identification of 5-hydroxymethylcytosine in genomic DNA. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel
• Leihne, VIbeke; Kirpekar, F; Vågbø, Cathrine Broberg; Van den Born, Erwin; Krokan, Hans Einar; Grini, Paul Eivind; Meza, Trine Johansen; Falnes, Pål. (2011) Roles of Trm9-and ALKBH8-like proteins in the formation of modified wobble uridines in Arabidopsis tRNA. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel
• Pettersen, Henrik Sahlin; Visnes, Torkild; Vågbø, Cathrine Broberg; Svaasand, Eva K; Doseth, Berit; Slupphaug, Geir; Kavli, Bodil Merete; Krokan, Hans Einar. (2011) UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel
• Van den Born, Erwin; Vågbø, Cathrine Broberg; Songe-Møller, Lene; Leihne, VIbeke; Lien, Guro Flor; Leszczynska, G; Malkiewicz, A; Krokan, Hans Einar; Kirpekar, F; Klungland, Arne. (2011) ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA. Nature Communications
  Vitenskapelig artikkel

2010

• Songe-Møller, Lene; Van den Born, Erwin; Leihne, V; Vågbø, Cathrine Broberg; Kristoffersen, T; Krokan, Hans Einar; Kirpekar, F; Falnes, PO; Klungland, A. (2010) Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding. Molecular and Cellular Biology
  Vitenskapelig artikkel

2009

• Gilljam, Karin Margaretha; Feyzi, Emadoldin; Aas, Per Arne; Sousa, Mirta; Müller, Rebekka; Vågbø, Cathrine Broberg; Catterall, Tara; Liabakk, Nina-Beate; Slupphaug, Geir; Drabløs, Finn. (2009) Identification of a novel, widespread, and functionally important PCNA-binding motif. Journal of Cell Biology
  Vitenskapelig artikkel

2008

• Sundheim, Ottar; Talstad, Vivi A; Vågbø, Cathrine Broberg; Slupphaug, Geir; Krokan, Hans Einar. (2008) AlkB demethylases flip out in different ways. DNA Repair
  Vitenskapelig artikkel
• Westbye, Marianne; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Talstad, Vivi A; Kavli, Bodil Merete; Hagen, Lars; Sundheim, Ottar; Akbari, Mansour; Liabakk, Nina-Beate. (2008) Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Vågbø, Cathrine Broberg. (2008) Direct repair of alkylation damage in DNA and RNA by  2-oxoglutarate- and iron-dependent dioxygenases. Norges teknisk-naturvitenskapelige universitet
  Doktoravhandling

2007

• Feyzi, Emadoldin; Aas, Per Arne; Sundheim, Ottar; Westbye, Marianne; Vågbø, Cathrine Broberg; Otterlei, Marit; Slupphaug, Geir; Krokan, Hans Einar. (2007) RNA Base Damage and Repair. Current Pharmaceutical Biotechnology
  Vitenskapelig oversiktsartikkel

2006

• Ringvoll, Jeanette; Ringvoll, Jeanette; Nordstrand, Line M.; Vågbø, Cathrine Broberg; Vagbo, CB; Talstad, Vivi; Reite, Karen; Aas, Per Arne; Lauritzen, Knut H.; Liabakk, Nina-Beate. (2006) Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA. EMBO Journal
  Vitenskapelig artikkel
• Sundheim, Ottar; Vågbø, Cathrine Broberg; Bjørås, Magnar; Mittelstedt, L.Mirta; Talstad, Vivi; Aas, Per Arne; Drabløs, Finn; Krokan, Hans Einar; Tainer, John A.; Slupphaug, Geir. (2006) Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. EMBO Journal
  Vitenskapelig artikkel

2004

• Drabløs, Finn; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Kavli, Bodil; Bratlie, Marit Skyrud; Diaz, Javier Pena; Otterlei, Marit; Slupphaug, Geir; Krokan, Hans Einar. (2004) Alkylation damage in DNA and RNA - repair mechanisms and medical significance. DNA Repair
  Vitenskapelig oversiktsartikkel

2003

• Aas, Per Arne; Otterlei, Marit; Falnes, P.Ø; Vågbø, Cathrine; Skorpen, Frank; Akbari, Mansour; Sundheim, Ottar; Bjørås, Magnar; Slupphaug, Geir; Seeberg, Erling Christen. (2003) Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. Nature
  Vitenskapelig artikkel

2001

• Chatton, Jean-Yves; Idle, Jefrrey R.; Vågbø, Cathrine; Magistretti, Pierre. (2001) Insights into the mechanisms of ifosfamide Encephalopathy:Drug Metabolites Have Agonistic Effects on a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid(AMPA) Kainate Receptors and Induce Cellular Acidification in Mouse Cortical Neurons. Journal of Pharmacology and Experimental Therapeutics
  Vitenskapelig artikkel