Ragnhild Sofie Ragnhildstveit Sætra
Om
Jeg er stipendiat i forskningsgruppa Molecular Mechanisms of Mycobacterial and HIV Infections ved Senter for molekylær inflammasjonsforskning (CEMIR). Vi studerer interaksjonene mellom Mycobacterium tuberculosis og dens vertsceller. I mitt prosjekt undersøker jeg disse mekanismene blant annet ved hjelp av fluorescensmikroskopi. Bakgrunnen min er fra sivilingeniørstudiet i nanoteknologi.
Publikasjoner
2025
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Hansen, Mathilde;
Sætra, Ragnhild Sofie Ragnhildstveit;
Bugge, Marit;
Flo, Trude Helen.
(2025)
Exploring NINJ1 in Mtb-induced cell death using genetically modified induced pluripotent stem cell (iPSC)-derived macrophages.
Annen presentasjon
2024
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Sætra, Ragnhild Sofie Ragnhildstveit;
Bugge, Marit;
Beckwith, Kai Sandvold;
Flo, Trude Helen.
(2024)
Ninjurin 1 and cell death mechanisms in Mycobacterium tuberculosis-infected human macrophages.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Doktorgradsavhandling
2022
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Borges, Jazlyn P.;
Sætra, Ragnhild Sofie Ragnhildstveit;
Volchuk, Allen;
Bugge, Marit;
Devant, Pascal;
Sporsheim, Bjørnar.
(2022)
Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death.
eLIFE
Vitenskapelig artikkel
2020
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Beckwith, Kai Sandvold;
Beckwith, Marianne Sandvold;
Ullmann, Sindre;
Sætra, Ragnhild Sofie Ragnhildstveit;
Kim, Hae Lin;
Marstad, Anne.
(2020)
Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection.
Nature Communications
Vitenskapelig artikkel
Tidsskriftspublikasjoner
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Borges, Jazlyn P.;
Sætra, Ragnhild Sofie Ragnhildstveit;
Volchuk, Allen;
Bugge, Marit;
Devant, Pascal;
Sporsheim, Bjørnar.
(2022)
Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death.
eLIFE
Vitenskapelig artikkel
-
Beckwith, Kai Sandvold;
Beckwith, Marianne Sandvold;
Ullmann, Sindre;
Sætra, Ragnhild Sofie Ragnhildstveit;
Kim, Hae Lin;
Marstad, Anne.
(2020)
Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection.
Nature Communications
Vitenskapelig artikkel
Rapport
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Sætra, Ragnhild Sofie Ragnhildstveit;
Bugge, Marit;
Beckwith, Kai Sandvold;
Flo, Trude Helen.
(2024)
Ninjurin 1 and cell death mechanisms in Mycobacterium tuberculosis-infected human macrophages.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Doktorgradsavhandling
UTSTILLING
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Hansen, Mathilde;
Sætra, Ragnhild Sofie Ragnhildstveit;
Bugge, Marit;
Flo, Trude Helen.
(2025)
Exploring NINJ1 in Mtb-induced cell death using genetically modified induced pluripotent stem cell (iPSC)-derived macrophages.
Annen presentasjon
Formidling
2024
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Vitenskapelig foredragFlo, Trude Helen; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Beckwith, Kai Sandvold; Hansen, Mathilde; Fjellvær, Ida. (2024) M. tuberculosis induced cell death and a new macrophage – alveolar epithelial cell co-culture model. EMBO|EMBL Symposium: Innate immunity in host-pathogen interactions , Heildelberg 18.06.2024 - 21.06.2024
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Vitenskapelig foredragFlo, Trude Helen; Sætra, Ragnhild Sofie Ragnhildstveit; Beckwith, Kai Sandvold; Marstad, Anne; Nonstad, Unni; Hansen, Mathilde. (2024) Control of mycobacterial infection by inflammasomes. EMBO workshop: The Inflammasomes-2024 , Planegg-Martinsried 23.09.2024 - 27.09.2027
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Vitenskapelig foredragSætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Marstad, Anne; Beckwith, Kai Sandvold; Flo, Trude Helen. (2024) Elucidating the role of NINJ1 in Mycobacterium tuberculosis-infected macrophages. TOLL Conference 2024 17.04.2024 - 20.04.2024
2023
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PosterSætra, Ragnhild Sofie Ragnhildstveit; Borges, Jazlyn P.; Volchuk, Allen; Bugge, Marit; Devant, Pascal; Marstad, Anne. (2023) NINJ1 oligomerization dynamics. 18th International Conference on Innate Immunity , Chania, Kreta 31.05.2023 - 05.06.2023
2022
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) Host-cell killing by Mycobacterium tuberculosis. Invited talk , Connecticut 26.04.2022 -
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) The inner life of a mycobacterium-infected macrophage. Invited talk , Connecticut 27.04.2022 -
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) The Inner Life of Mycobacterium Infected Macrophages. Gordon Research Conference on Lysosomes and Endocytosis 2022: Physiological Adaptations of the Endo-Lysosomal System , Andover, New Hampshire 19.06.2022 - 24.06.2022
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Bugge, Marit; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre. (2022) The inner life of a mycobacterium-infected macrophage. NIAID Invited talk , Bethesda 19.05.2022 -
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Mediaas, Sindre Dahl; Sætra, Ragnhild Sofie Ragnhildstveit. (2022) Spatiotemporal Relations of Mycobacteria and Human Macrophages. Department seminar series , Massachusetts 26.01.2022 -
2021
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit. (2021) Mycobacterium tuberculosis infection in human macrophages. Department seminar series 15.09.2021 -
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Vitenskapelig foredragSætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Marstad, Anne; Flo, Trude Helen. (2021) MOLECULAR MECHANISMS IN MYCOBACTERIUM TUBERCULOSIS-INFECTED MACROPHAGES. IBA Annual Meeting 2021 , Oslo 01.11.2021 - 02.11.2021
2020
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PosterBeckwith, Marianne Sandvold; Beckwith, Kai Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Kim, Haelin. (2020) Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection. Keystone Symposium Tuberculosis , Santa Fe, New Mexico 16.01.2020 - 21.01.2020
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PosterSætra, Ragnhild Sofie Ragnhildstveit; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Kim, Haelin; Marstad, Anne. (2020) Mechanisms in human macrophages infected with Mycobacterium tuberculosis. IBA Annual meeting , Zoom 26.10.2020 - 27.10.2020
2019
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Strand, Trine Aakvik. (2019) Balancing life and death in mycobacterium-infected macrophages. 2nd International conference on molecular mechanisms of inflammation , Trondheim 03.06.2019 - 06.06.2019
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne. (2019) Single-cell dynamics of NLRP3 inflammasome activation and pyroptosis during Mycobacterium tuberculosis infection of human macrophages. IUIS2019 17th International Congress of Immunology , Beijing 19.10.2019 - 23.10.2019
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PosterBeckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Åsberg, Signe. (2019) Plasma membrane damage during Mycobacterium tuberculosis infection. The 4th Turning the Tide of Antimicrobial resistance meeting 18.11.2019 - 20.11.2019
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PosterUllmann, Sindre; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Åsberg, Signe. (2019) Catching the moment - Correlative Light Electron Microscopy (CLEM) to study hostpathogen interactions in single cells, at ultimate spatial and temporal resolutions. Conference on Molecular Mechanisms of Inflammation , Trondheim 03.06.2019 - 06.06.2019
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PosterUllmann, Sindre; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Strand, Trine Aakvik. (2019) Catching the moment - Correlative Light Electron Microscopy (CLEM) to study hostpathogen interactions in single cells, at ultimate spatial and temporal resolutions. The 4th Turning the Tide of Antimicrobial resistance meeting , Oslo 18.11.2019 - 20.11.2019
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PosterUllmann, Sindre; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Beckwith, Marianne Sandvold; Beckwith, Kai Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit. (2019) Correlative light-electron microscopy investigations of single-cell dynamics in Mycobacteria tuberculosis infected human macrophages. Seeing is Believing - Imaging the Molecular Processes of Life , EMBL Heidelberg 09.10.2019 - 12.10.2019
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Vitenskapelig foredragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit. (2019) Plasma membrane damage by Mycobacterium tuberculosis induce inflammasome activation and pyroptosis in host macrophages. International Symposium on Discovery of Actionable Targets in Infectious Diseases , Mangalore 26.11.2019 - 26.11.2019
2018
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Faglig foredragBeckwith, Kai Sandvold; Beckwith, Marianne; Ullmann, Sindre; Åsberg, Signe; Sætra, Ragnhild Sofie Ragnhildstveit; Strand, Trine Aakvik. (2018) Damage and repair of host cell membranes during M. Tuberculosis infection. EMBL seminar , Heidelberg 06.12.2018 - 06.12.2018