Ragnhild Sofie Ragnhildstveit Sætra
Om
Jeg er stipendiat i forskningsgruppa Molecular Mechanisms of Mycobacterial and HIV Infections ved Senter for molekylær inflammasjonsforskning (CEMIR). Vi studerer interaksjonene mellom Mycobacterium tuberculosis og dens vertsceller. I mitt prosjekt undersøker jeg disse mekanismene blant annet ved hjelp av fluorescensmikroskopi. Bakgrunnen min er fra sivilingeniørstudiet i nanoteknologi.
Publikasjoner
2024
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Sætra, Ragnhild Sofie Ragnhildstveit;
Bugge, Marit;
Beckwith, Kai Sandvold;
Flo, Trude Helen.
(2024)
Ninjurin 1 and cell death mechanisms in Mycobacterium tuberculosis-infected human macrophages.
Norges teknisk-naturvitenskapelige universitet
Doktoravhandling
2022
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Borges, Jazlyn P.;
Sætra, Ragnhild Sofie Ragnhildstveit;
Volchuk, Allen;
Bugge, Marit;
Devant, Pascal;
Sporsheim, Bjørnar;
Kilburn, Bridget R.;
Evavold, Charles L.;
Kagan, Jonathan C.;
Goldenberg, Neil M..
(2022)
Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death.
eLIFE
Vitenskapelig artikkel
2020
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Beckwith, Kai Sandvold;
Beckwith, Marianne Sandvold;
Ullmann, Sindre;
Sætra, Ragnhild Sofie Ragnhildstveit;
Kim, Hae Lin;
Marstad, Anne;
Åsberg, Signe Elisabeth;
Strand, Trine Aakvik;
Haug, Markus;
Niederweis, Michael.
(2020)
Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection.
Nature Communications
Vitenskapelig artikkel
Tidsskriftspublikasjoner
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Beckwith, Kai Sandvold;
Beckwith, Marianne Sandvold;
Ullmann, Sindre;
Sætra, Ragnhild Sofie Ragnhildstveit;
Kim, Hae Lin;
Marstad, Anne;
Åsberg, Signe Elisabeth;
Strand, Trine Aakvik;
Haug, Markus;
Niederweis, Michael.
(2020)
Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection.
Nature Communications
Vitenskapelig artikkel
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Borges, Jazlyn P.;
Sætra, Ragnhild Sofie Ragnhildstveit;
Volchuk, Allen;
Bugge, Marit;
Devant, Pascal;
Sporsheim, Bjørnar;
Kilburn, Bridget R.;
Evavold, Charles L.;
Kagan, Jonathan C.;
Goldenberg, Neil M..
(2022)
Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death.
eLIFE
Vitenskapelig artikkel
Studentoppgave eller avhandling
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Sætra, Ragnhild Sofie Ragnhildstveit;
Bugge, Marit;
Beckwith, Kai Sandvold;
Flo, Trude Helen.
(2024)
Ninjurin 1 and cell death mechanisms in Mycobacterium tuberculosis-infected human macrophages.
Norges teknisk-naturvitenskapelige universitet
Doktoravhandling
Formidling
2025
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Annen presentasjonHansen, Mathilde; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Flo, Trude Helen. (2025) Exploring NINJ1 in Mtb-induced cell death using genetically modified induced pluripotent stem cell (iPSC)-derived macrophages. NBS contact meeting 2025
2024
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KonferanseforedragFlo, Trude Helen; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Beckwith, Kai Sandvold; Hansen, Mathilde; Fjellvær, Ida; Lacour, Clement Edgar Marius; Marstad, Anne; Nonstad, Unni; Devant, Pascal. (2024) M. tuberculosis induced cell death and a new macrophage – alveolar epithelial cell co-culture model. EMBO|EMBL Symposium: Innate immunity in host-pathogen interactions
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KonferanseforedragFlo, Trude Helen; Sætra, Ragnhild Sofie Ragnhildstveit; Beckwith, Kai Sandvold; Marstad, Anne; Nonstad, Unni; Hansen, Mathilde; Bugge, Marit; Kappelhoff, Shirin. (2024) Control of mycobacterial infection by inflammasomes. EMBO workshop: The Inflammasomes-2024
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KonferanseforedragSætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Marstad, Anne; Beckwith, Kai Sandvold; Flo, Trude Helen. (2024) Elucidating the role of NINJ1 in Mycobacterium tuberculosis-infected macrophages. TOLL Conference 2024
2023
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KonferanseposterSætra, Ragnhild Sofie Ragnhildstveit; Borges, Jazlyn P.; Volchuk, Allen; Bugge, Marit; Devant, Pascal; Marstad, Anne; Sporsheim, Bjørnar; Kilburn, Bridget R.; Evavold, Charles L.; Kagan, Jonathan C.. (2023) NINJ1 oligomerization dynamics. 18th International Conference on Innate Immunity
2022
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) Host-cell killing by Mycobacterium tuberculosis. Invited talk
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) The inner life of a mycobacterium-infected macrophage. Invited talk
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre; Bugge, Marit. (2022) The Inner Life of Mycobacterium Infected Macrophages. Gordon Research Conference on Lysosomes and Endocytosis 2022: Physiological Adaptations of the Endo-Lysosomal System
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Bugge, Marit; Sætra, Ragnhild Sofie Ragnhildstveit; Ullmann, Sindre. (2022) The inner life of a mycobacterium-infected macrophage. NIAID Invited talk
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Mediaas, Sindre Dahl; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Ullmann, Sindre; Åsberg, Signe Elisabeth. (2022) Spatiotemporal Relations of Mycobacteria and Human Macrophages. Department seminar series
2021
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit. (2021) Mycobacterium tuberculosis infection in human macrophages. Department seminar series
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KonferanseforedragSætra, Ragnhild Sofie Ragnhildstveit; Bugge, Marit; Marstad, Anne; Flo, Trude Helen. (2021) MOLECULAR MECHANISMS IN MYCOBACTERIUM TUBERCULOSIS-INFECTED MACROPHAGES. IBA Annual Meeting 2021
2020
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KonferanseposterBeckwith, Marianne Sandvold; Beckwith, Kai Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Kim, Haelin; Åsberg, Signe Elisabeth; Strand, Trine Aakvik; Haug, Markus; Niederweis, Michael. (2020) Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection. Keystone Symposium Tuberculosis
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KonferanseposterSætra, Ragnhild Sofie Ragnhildstveit; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Kim, Haelin; Marstad, Anne; Åsberg, Signe Elisabeth; Strand, Trine Aakvik; Flo, Trude Helen. (2020) Mechanisms in human macrophages infected with Mycobacterium tuberculosis. IBA Annual meeting
2019
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Strand, Trine Aakvik; Marstad, Anne; Åsberg, Signe; Stenmark, Harald. (2019) Balancing life and death in mycobacterium-infected macrophages. 2nd International conference on molecular mechanisms of inflammation
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Strand, Trine Aakvik; Stenmark, Harald; Åsberg, Signe. (2019) Single-cell dynamics of NLRP3 inflammasome activation and pyroptosis during Mycobacterium tuberculosis infection of human macrophages. IUIS2019 17th International Congress of Immunology
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KonferanseposterBeckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Plasma membrane damage during Mycobacterium tuberculosis infection. The 4th Turning the Tide of Antimicrobial resistance meeting
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KonferanseposterUllmann, Sindre; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Catching the moment - Correlative Light Electron Microscopy (CLEM) to study hostpathogen interactions in single cells, at ultimate spatial and temporal resolutions. Conference on Molecular Mechanisms of Inflammation
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KonferanseposterUllmann, Sindre; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Marstad, Anne; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Catching the moment - Correlative Light Electron Microscopy (CLEM) to study hostpathogen interactions in single cells, at ultimate spatial and temporal resolutions. The 4th Turning the Tide of Antimicrobial resistance meeting
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KonferanseposterUllmann, Sindre; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Beckwith, Marianne Sandvold; Beckwith, Kai Sandvold; Sætra, Ragnhild Sofie Ragnhildstveit; Åsberg, Signe; Strand, Trine Aakvik; Flo, Trude Helen. (2019) Correlative light-electron microscopy investigations of single-cell dynamics in Mycobacteria tuberculosis infected human macrophages. Seeing is Believing - Imaging the Molecular Processes of Life
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KonferanseforedragFlo, Trude Helen; Beckwith, Kai Sandvold; Beckwith, Marianne Sandvold; Gidon, Alexandre; Ullmann, Sindre; Sætra, Ragnhild Sofie Ragnhildstveit. (2019) Plasma membrane damage by Mycobacterium tuberculosis induce inflammasome activation and pyroptosis in host macrophages. International Symposium on Discovery of Actionable Targets in Infectious Diseases
2018
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ForedragBeckwith, Kai Sandvold; Beckwith, Marianne; Ullmann, Sindre; Åsberg, Signe; Sætra, Ragnhild Sofie Ragnhildstveit; Strand, Trine Aakvik; Flo, Trude Helen. (2018) Damage and repair of host cell membranes during M. Tuberculosis infection. EMBL seminar