Oddgeir Lingaas Holmen
Om
Data for en bedre verden!
Min forskning har fokusert på sammenhenger mellom genetisk variasjon og sykdommer på befolkningsnivå.
Nå brenner jeg for å øke verdien av store helsedata for å bedre sykdomsforebygging og behandling.
Publikasjoner
2024
-
Helgeland, Øyvind;
Vaudel, Marc;
Sole-Navais, Pol;
Flatley, Christopher;
Juodakis, Julius;
Bacelis, Jonas.
(2024)
Correction to: Characterization of the genetic architecture of infant and early childhood body mass index (Nature Metabolism, (2022), 4, 3, (344-358), 10.1038/s42255-022-00549-1).
Nature Metabolism
Errata
2023
-
Lagou, Vasiliki;
Jiang, Longda;
Ulrich, Anna;
Zudina, Liudmila;
González, Karla Sofia Gutiérrez;
Balkhiyarova, Zhanna.
(2023)
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Nature Genetics
Vitenskapelig artikkel
2022
-
Helgeland, Øyvind;
Vaudel, Marc;
Sole-Navais, Pol;
Flatley, Christopher;
Juodakis, Julius;
Bacelis, Jonas.
(2022)
Characterization of the genetic architecture of infant and early childhood body mass index.
Nature Metabolism
Vitenskapelig artikkel
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G..
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics
Vitenskapelig artikkel
-
Bahrami, Shahram;
Hindley, Guy Frederick Lanyon;
Winsvold, Bendik K S;
O'Connell, Kevin Sean;
Frei, Oleksandr;
Shadrin, Alexey.
(2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.
Brain
Vitenskapelig artikkel
2021
-
Freidin, Maxim B.;
Tsepilov, Yakov A.;
Stanaway, Ian B.;
Meng, Weihua;
Hayward, Caroline;
Smith, Blair H..
(2021)
Sex- and age-specific genetic analysis of chronic back pain.
Pain
Vitenskapelig artikkel
-
Bianchini, Federico;
Birkeland, Even;
Bösl, Korbinian;
Gade, Alexandra;
Holmen, Oddgeir Lingaas;
Hu, Xian.
(2021)
BioMedData Deliverable D2.1 - Report on data management plan needs/gaps.
Zenodo
Rapport
2020
-
Nielsen, Jonas Bille;
Rom, Oren;
Surakka, Ida;
Graham, Sarah E.;
Zhou, Wei;
Roychowdhury, Tanmoy.
(2020)
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nature Communications
Vitenskapelig artikkel
2019
-
Rounge, Trine Ballestad;
Lauritzen, Marianne;
Erlandsen, Sten Even;
Langseth, Hilde;
Holmen, Oddgeir Lingaas;
Gislefoss, Randi Elin.
(2019)
Ultralow amounts of DNA from long-term archived serum samples produce quality genotypes.
European Journal of Human Genetics
Vitenskapelig artikkel
-
Justice, Anne E.;
Karaderi, Tugce;
Highland, Heather M.;
Young, Kristin L.;
Graff, Mariaelisa;
Lu, Yingchang.
(2019)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Nature Genetics
Vitenskapelig artikkel
-
Lyngbakken, Magnus;
Røsjø, Helge;
Holmen, Oddgeir Lingaas;
Dalen, Håvard;
Hveem, Kristian;
Omland, Torbjørn.
(2019)
Temporal changes in cardiac troponin i are associated with risk of cardiovascular events in the general population: The Nord-Trøndelag health study.
Clinical Chemistry
Vitenskapelig artikkel
-
Helgeland, Øyvind;
Vaudel, Marc;
Juliusson, Petur Benedikt;
Holmen, Oddgeir Lingaas;
Juodakis, Julius;
Bacelis, Jonas.
(2019)
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth.
Nature Communications
Vitenskapelig artikkel
-
Turcot, Valérie;
Lu, Yingchang;
Highland, Heather M.;
Schurmann, Claudia;
Justice, Anne E.;
Fine, Rebecca S..
(2019)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x).
Nature Genetics
Errata
2018
-
Nielsen, Jonas B.;
Thorolfsdottir, Rosa B.;
Fritsche, Lars;
Zhou, Wei;
Skov, Morten W.;
Graham, Sarah E..
(2018)
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
Nature Genetics
Vitenskapelig artikkel
-
Thorolfsdottir, Rosa B;
Sveinbjornsson, Gardar;
Sulem, Patrick;
Nielsen, Jonas B.;
Jonsson, Stefan;
Halldorsson, Gisli H.
(2018)
Coding variants in RPL3L and MYZAP increase risk of atrial
fibrillation.
Communications Biology
Vitenskapelig artikkel
-
Gusarova, Viktoria;
O'Dushlaine, Colm;
Teslovich, Tanya M.;
Benotti, Peter N.;
Mirshahi, Tooraj;
Gottesman, Omri.
(2018)
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.
Nature Communications
Vitenskapelig artikkel
-
Nielsen, Jonas B.;
Fritsche, Lars;
Zhou, Wei;
Teslovich, Tanya M.;
Holmen, Oddgeir Lingaas;
Gustafsson, Stefan.
(2018)
Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development.
American Journal of Human Genetics
Vitenskapelig artikkel
-
Løset, Mari;
Modalsli, Ellen Heilmann;
Snekvik, Ingrid;
Solvin, Åshild Øksnevad;
Holmen, Oddgeir Lingaas;
Gabrielsen, Maiken Elvestad.
(2018)
743 HUNTing for genes that affect inflammatory skin disease in 4,071 cases and 40,430 controls.
Journal of Investigative Dermatology
Sammendrag/abstract
-
Turcot, Valérie;
Lu, Yingchang;
Highland, Heather M.;
Schurmann, Claudia;
Justice, Anne E.;
Fine, Rebecca S..
(2018)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics
Vitenskapelig artikkel
-
Sigurdardottir, Fjola Dogg;
Lyngbakken, Magnus Nakrem;
Holmen, Oddgeir Lingaas;
Dalen, Håvard;
Hveem, Kristian;
Røsjø, Helge.
(2018)
Relative prognostic value of cardiac troponin I and C-reactive protein in the general population (from the Nord-Trøndelag Health [HUNT] Study).
American Journal of Cardiology
Vitenskapelig artikkel
-
Turcot, Valérie;
Helgeland, Øyvind;
Holmen, Oddgeir Lingaas;
Johansson, Stefan;
Njølstad, Pål Rasmus;
Loos, Ruth J.F..
(2018)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics
Errata
2017
-
Ferreira, Manuel A.;
Vonk, Judith M;
Baurecht, Hansjörg;
Marenholz, Ingo;
Tian, Chao;
Hoffman, Joshua D.
(2017)
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Nature Genetics
Vitenskapelig artikkel
-
Graff, Mariaelisa;
Scott, Robert A.;
Justice, Anne E.;
Young, Kristin L.;
Feitosa, Mary F.;
Barata, Llilda.
(2017)
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
PLoS Genetics
Vitenskapelig artikkel
-
Justice, Anne E.;
Winkler, Thomas W.;
Feitosa, Mary F.;
Graff, Misa;
Fisher, Virginia A.;
Young, Kristin.
(2017)
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
Nature Communications
Vitenskapelig artikkel
-
Webb, Thomas R.;
Erdmann, Jeanette;
Stirrups, Kathleen E.;
Stitziel, Nathan O.;
Masca, Nicholas G.D.;
Jansen, Henning.
(2017)
Systematic evaluation of pleiotropy identifies 6 further loci associated with coronary artery disease.
Journal of the American College of Cardiology
Vitenskapelig artikkel
-
Liu, Dajiang J.;
Peloso, Gina M.;
Yu, Haojie;
Butterworth, Adam S.;
Wang, Xiao;
Mahajan, Anubha.
(2017)
Exome-wide association study of plasma lipids in >300,000 individuals.
Nature Genetics
Vitenskapelig artikkel
-
Zhou, Wei;
Fritsche, Lars;
Das, Sayantan;
Zhang, He;
Nielsen, Jonas B.;
Holmen, Oddgeir Lingaas.
(2017)
Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels.
Genetic Epidemiology
Vitenskapelig artikkel
2016
-
Ehret, Georg B.;
Ferreira, Teresa;
Chasman, Daniel I.;
Jackson, Anne U.;
Schmidt, Ellen M.;
Johnson, Toby.
(2016)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
Nature Genetics
Vitenskapelig artikkel
-
Lyngbakken, Magnus Nakrem;
Røsjø, Helge;
Holmen, Oddgeir;
Nygård, Ståle;
Dalen, Håvard;
Hveem, Kristian.
(2016)
Gender, High-Sensitivity Troponin I, and the Risk of Cardiovascular Events (from the Nord-Trøndelag Health Study).
American Journal of Cardiology
Vitenskapelig artikkel
-
Zayats, Tetyana;
Jacobsen, Kaya Kvarme;
Kleppe, Rune;
Jacob, CP;
Kittel-Schneider, Sarah;
Ribases, Marta.
(2016)
Exome chip analyses in adult attention deficit hyperactivity disorder.
Translational Psychiatry
Vitenskapelig artikkel
-
Ried, Janina S.;
Jeff, Janina M.;
Chu, Audrey Y.;
Bragg-Gresham, Jennifer L.;
Van Dongen, Jenny;
Huffman, Jennifer E..
(2016)
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.
Nature Communications
Vitenskapelig artikkel
-
Løset, Mari;
Modalsli, Ellen Heilmann;
Snekvik, Ingrid;
Zhou, Wei;
Chu, Yunhan;
Gabrielsen, Maiken Elvestad.
(2016)
HUNTing for Genes that Affect Psoriasis in ~2,900 Cases and ~48,000 Controls.
Forum for Nordic Dermato-Venereology
Sammendrag/abstract
-
Surendran, Praveen;
Drenos, Fotios;
Young, Robin;
Warren, Helen;
Cook, James P.;
Manning, Alisa K..
(2016)
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Nature Genetics
Vitenskapelig artikkel
-
Holmen, Jostein;
Holmen, Turid Lingaas;
Tverdal, Aage;
Holmen, Oddgeir;
Sund, Erik Reidar;
Midthjell, Kristian.
(2016)
Blood pressure changes during 22-year of follow-up in large general population - the HUNT Study, Norway.
BMC Cardiovascular Disorders
Vitenskapelig artikkel
-
Stitziel, Nathan O.;
Stirrups, Kathleen E.;
Masca, Nicholas G.D.;
Erdmann, Jeanette;
Ferrario, Paola G.;
König, Inke R..
(2016)
Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease.
New England Journal of Medicine
Vitenskapelig artikkel
2015
-
Locke, Adam E.;
Kahali, Bratati;
Berndt, Sonja I.;
Justice, Anne E.;
Pers, Tune H.;
Day, Felix R..
(2015)
Genetic studies of body mass index yield new insights for obesity biology.
Nature
Vitenskapelig artikkel
-
Shungin, Dmitry;
Winkler, Thomas W.;
Croteau-Chonka, Damien C.;
Ferreira, Teresa;
Locke, Adam E.;
Mägi, Reedik.
(2015)
New genetic loci link adipose and insulin biology to body fat distribution.
Nature
Vitenskapelig artikkel
-
Tang, Clara S.;
Zhang, He;
Cheung, Chloe Y.Y.;
Xu, Ming;
Ho, Jenny C.Y.;
Zhou, Wei.
(2015)
Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.
Nature Communications
Vitenskapelig artikkel
-
Gaulton, Kyle J.;
Ferreira, Teresa;
Lee, Yeji;
Raimondo, Anne;
Mägi, Reedik;
Reschen, Michael E..
(2015)
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Nature Genetics
Vitenskapelig artikkel
-
Omland, Torbjørn;
De Lemos, James A;
Holmen, Oddgeir;
Dalen, Håvard;
Saltyte Benth, Jurate;
Nygård, Ståle.
(2015)
Impact of sex on the prognostic value of high-sensitivity cardiac troponin I in the general population: The HUNT study.
Clinical Chemistry
Vitenskapelig artikkel
-
Feng, Shuang;
Pistis, Giorgio;
Zhang, He;
Zawistowski, Matthew;
Mulas, Antonella;
Zoledziewska, Magdalena.
(2015)
Methods for association analysis and meta-analysis of rare variants in families.
Genetic Epidemiology
Vitenskapelig artikkel
2014
-
Mahajan, Anubha;
Go, Min Jin;
Zhang, Weihua;
Below, Jennifer E;
Gaulton, Kyle J;
Ferreira, Teresa.
(2014)
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Nature Genetics
Vitenskapelig artikkel
-
Kvehaugen, Anne Stine;
Melien, Øyvind;
Holmen, Oddgeir;
Laivuori, Hannele;
Dechend, Ralf;
Staff, Anne Cathrine.
(2014)
Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: Data from the Norwegian HUNT2 study.
BMC Medical Genetics
Vitenskapelig artikkel
-
Lange, LA;
Hu, Y;
Zhang, H;
Xue, C;
Schmidt, EM;
Tang, ZZ.
(2014)
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
American Journal of Human Genetics
Vitenskapelig artikkel
-
Liu, Dajiang J.;
Peloso, Gina M.;
Zhan, Xiaowei;
Holmen, Oddgeir;
Zawistowski, Matthew;
Feng, Shuang.
(2014)
Meta-analysis of gene-level tests for rare variant association.
Nature Genetics
Vitenskapelig artikkel
-
Wood, Andrew R.;
Esko, Tonu;
Yang, Jian;
Vedantam, Sailaja;
Pers, Tune H;
Gustafsson, Stefan.
(2014)
Defining the role of common variation in the genomic and biological architecture of adult human height.
Nature Genetics
Vitenskapelig artikkel
-
Crosby, Jacy;
Peloso, Gina M;
Auer, Paul L;
Crosslin, David R;
Stitziel, Nathan O;
Lange, Leslie A.
(2014)
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
New England Journal of Medicine
Vitenskapelig artikkel
-
Holmen, Oddgeir;
Zhang, He;
Zhou, Wei;
Schmidt, Ellen;
Hovelson, Daniel H;
Langhammer, Arnulf.
(2014)
No large-effect low-frequency coding variation found for myocardial infarction.
Human Molecular Genetics
Vitenskapelig artikkel
-
Holmen, Oddgeir;
Zhang, He;
Fan , Yanbo;
Hovelson, Daniel H;
Schmidt, EM;
Zhou , Wei.
(2014)
Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk.
Nature Genetics
Vitenskapelig artikkel
2013
-
Kvehaugen, Anne Stine;
Melien, Øyvind;
Holmen, Oddgeir;
Laivuori, Hannele;
Øian, Pål;
Andersgaard, Alice Beathe.
(2013)
Single Nucleotide Polymorphisms in G Protein Signaling Pathway Genes in Preeclampsia.
Hypertension
Vitenskapelig artikkel
-
Wu, Y;
Waite, LL;
Jackson, Anne U.;
Sheu, WHH;
Buyske, Steven;
Absher, D.
(2013)
Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained.
PLoS Genetics
Vitenskapelig artikkel
2012
-
Morris, AP;
Voight, BF;
Teslovich, TM;
Ferreira, T;
Segre, AV;
Steinthorsdottir, V.
(2012)
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Nature Genetics
Vitenskapelig artikkel
2011
-
Chan, Y;
Holmen, Oddgeir;
Dauber, A;
Vatten, Lars Johan;
Havulinna, AS;
Skorpen, Frank.
(2011)
Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals.
PLoS Genetics
Vitenskapelig artikkel
2010
-
Holmen, Oddgeir;
Romundstad, Solfrid;
Melien, Øyvind.
(2010)
Association Between the G Protein beta 3 Subunit C825T Polymorphism and the Occurrence of Cardiovascular Disease in Hypertensives: The Nord-Trondelag Health Study (HUNT).
American Journal of Hypertension
Vitenskapelig artikkel
Tidsskriftspublikasjoner
-
Helgeland, Øyvind;
Vaudel, Marc;
Sole-Navais, Pol;
Flatley, Christopher;
Juodakis, Julius;
Bacelis, Jonas.
(2024)
Correction to: Characterization of the genetic architecture of infant and early childhood body mass index (Nature Metabolism, (2022), 4, 3, (344-358), 10.1038/s42255-022-00549-1).
Nature Metabolism
Errata
-
Lagou, Vasiliki;
Jiang, Longda;
Ulrich, Anna;
Zudina, Liudmila;
González, Karla Sofia Gutiérrez;
Balkhiyarova, Zhanna.
(2023)
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Nature Genetics
Vitenskapelig artikkel
-
Helgeland, Øyvind;
Vaudel, Marc;
Sole-Navais, Pol;
Flatley, Christopher;
Juodakis, Julius;
Bacelis, Jonas.
(2022)
Characterization of the genetic architecture of infant and early childhood body mass index.
Nature Metabolism
Vitenskapelig artikkel
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G..
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics
Vitenskapelig artikkel
-
Bahrami, Shahram;
Hindley, Guy Frederick Lanyon;
Winsvold, Bendik K S;
O'Connell, Kevin Sean;
Frei, Oleksandr;
Shadrin, Alexey.
(2022)
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools.
Brain
Vitenskapelig artikkel
-
Freidin, Maxim B.;
Tsepilov, Yakov A.;
Stanaway, Ian B.;
Meng, Weihua;
Hayward, Caroline;
Smith, Blair H..
(2021)
Sex- and age-specific genetic analysis of chronic back pain.
Pain
Vitenskapelig artikkel
-
Nielsen, Jonas Bille;
Rom, Oren;
Surakka, Ida;
Graham, Sarah E.;
Zhou, Wei;
Roychowdhury, Tanmoy.
(2020)
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Nature Communications
Vitenskapelig artikkel
-
Rounge, Trine Ballestad;
Lauritzen, Marianne;
Erlandsen, Sten Even;
Langseth, Hilde;
Holmen, Oddgeir Lingaas;
Gislefoss, Randi Elin.
(2019)
Ultralow amounts of DNA from long-term archived serum samples produce quality genotypes.
European Journal of Human Genetics
Vitenskapelig artikkel
-
Justice, Anne E.;
Karaderi, Tugce;
Highland, Heather M.;
Young, Kristin L.;
Graff, Mariaelisa;
Lu, Yingchang.
(2019)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution.
Nature Genetics
Vitenskapelig artikkel
-
Lyngbakken, Magnus;
Røsjø, Helge;
Holmen, Oddgeir Lingaas;
Dalen, Håvard;
Hveem, Kristian;
Omland, Torbjørn.
(2019)
Temporal changes in cardiac troponin i are associated with risk of cardiovascular events in the general population: The Nord-Trøndelag health study.
Clinical Chemistry
Vitenskapelig artikkel
-
Helgeland, Øyvind;
Vaudel, Marc;
Juliusson, Petur Benedikt;
Holmen, Oddgeir Lingaas;
Juodakis, Julius;
Bacelis, Jonas.
(2019)
Genome-wide association study reveals dynamic role of genetic variation in infant and early childhood growth.
Nature Communications
Vitenskapelig artikkel
-
Turcot, Valérie;
Lu, Yingchang;
Highland, Heather M.;
Schurmann, Claudia;
Justice, Anne E.;
Fine, Rebecca S..
(2019)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x).
Nature Genetics
Errata
-
Nielsen, Jonas B.;
Thorolfsdottir, Rosa B.;
Fritsche, Lars;
Zhou, Wei;
Skov, Morten W.;
Graham, Sarah E..
(2018)
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
Nature Genetics
Vitenskapelig artikkel
-
Thorolfsdottir, Rosa B;
Sveinbjornsson, Gardar;
Sulem, Patrick;
Nielsen, Jonas B.;
Jonsson, Stefan;
Halldorsson, Gisli H.
(2018)
Coding variants in RPL3L and MYZAP increase risk of atrial
fibrillation.
Communications Biology
Vitenskapelig artikkel
-
Gusarova, Viktoria;
O'Dushlaine, Colm;
Teslovich, Tanya M.;
Benotti, Peter N.;
Mirshahi, Tooraj;
Gottesman, Omri.
(2018)
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.
Nature Communications
Vitenskapelig artikkel
-
Nielsen, Jonas B.;
Fritsche, Lars;
Zhou, Wei;
Teslovich, Tanya M.;
Holmen, Oddgeir Lingaas;
Gustafsson, Stefan.
(2018)
Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development.
American Journal of Human Genetics
Vitenskapelig artikkel
-
Løset, Mari;
Modalsli, Ellen Heilmann;
Snekvik, Ingrid;
Solvin, Åshild Øksnevad;
Holmen, Oddgeir Lingaas;
Gabrielsen, Maiken Elvestad.
(2018)
743 HUNTing for genes that affect inflammatory skin disease in 4,071 cases and 40,430 controls.
Journal of Investigative Dermatology
Sammendrag/abstract
-
Turcot, Valérie;
Lu, Yingchang;
Highland, Heather M.;
Schurmann, Claudia;
Justice, Anne E.;
Fine, Rebecca S..
(2018)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics
Vitenskapelig artikkel
-
Sigurdardottir, Fjola Dogg;
Lyngbakken, Magnus Nakrem;
Holmen, Oddgeir Lingaas;
Dalen, Håvard;
Hveem, Kristian;
Røsjø, Helge.
(2018)
Relative prognostic value of cardiac troponin I and C-reactive protein in the general population (from the Nord-Trøndelag Health [HUNT] Study).
American Journal of Cardiology
Vitenskapelig artikkel
-
Turcot, Valérie;
Helgeland, Øyvind;
Holmen, Oddgeir Lingaas;
Johansson, Stefan;
Njølstad, Pål Rasmus;
Loos, Ruth J.F..
(2018)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Nature Genetics
Errata
-
Ferreira, Manuel A.;
Vonk, Judith M;
Baurecht, Hansjörg;
Marenholz, Ingo;
Tian, Chao;
Hoffman, Joshua D.
(2017)
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.
Nature Genetics
Vitenskapelig artikkel
-
Graff, Mariaelisa;
Scott, Robert A.;
Justice, Anne E.;
Young, Kristin L.;
Feitosa, Mary F.;
Barata, Llilda.
(2017)
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
PLoS Genetics
Vitenskapelig artikkel
-
Justice, Anne E.;
Winkler, Thomas W.;
Feitosa, Mary F.;
Graff, Misa;
Fisher, Virginia A.;
Young, Kristin.
(2017)
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.
Nature Communications
Vitenskapelig artikkel
-
Webb, Thomas R.;
Erdmann, Jeanette;
Stirrups, Kathleen E.;
Stitziel, Nathan O.;
Masca, Nicholas G.D.;
Jansen, Henning.
(2017)
Systematic evaluation of pleiotropy identifies 6 further loci associated with coronary artery disease.
Journal of the American College of Cardiology
Vitenskapelig artikkel
-
Liu, Dajiang J.;
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Improving power of association tests using multiple sets of imputed genotypes from distributed reference panels.
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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
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Gender, High-Sensitivity Troponin I, and the Risk of Cardiovascular Events (from the Nord-Trøndelag Health Study).
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Exome chip analyses in adult attention deficit hyperactivity disorder.
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A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.
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HUNTing for Genes that Affect Psoriasis in ~2,900 Cases and ~48,000 Controls.
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Surendran, Praveen;
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Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
Nature Genetics
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Holmen, Jostein;
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Blood pressure changes during 22-year of follow-up in large general population - the HUNT Study, Norway.
BMC Cardiovascular Disorders
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Stitziel, Nathan O.;
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Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease.
New England Journal of Medicine
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Locke, Adam E.;
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Genetic studies of body mass index yield new insights for obesity biology.
Nature
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Shungin, Dmitry;
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New genetic loci link adipose and insulin biology to body fat distribution.
Nature
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Tang, Clara S.;
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Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.
Nature Communications
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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Nature Genetics
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Omland, Torbjørn;
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Impact of sex on the prognostic value of high-sensitivity cardiac troponin I in the general population: The HUNT study.
Clinical Chemistry
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Methods for association analysis and meta-analysis of rare variants in families.
Genetic Epidemiology
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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Nature Genetics
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Kvehaugen, Anne Stine;
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Hypertension after preeclampsia and relation to the C1114G polymorphism (rs4606) in RGS2: Data from the Norwegian HUNT2 study.
BMC Medical Genetics
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Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.
American Journal of Human Genetics
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Nature Genetics
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Defining the role of common variation in the genomic and biological architecture of adult human height.
Nature Genetics
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Crosby, Jacy;
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Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
New England Journal of Medicine
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No large-effect low-frequency coding variation found for myocardial infarction.
Human Molecular Genetics
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Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk.
Nature Genetics
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Hypertension
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Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained.
PLoS Genetics
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Morris, AP;
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Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
Nature Genetics
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Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals.
PLoS Genetics
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Association Between the G Protein beta 3 Subunit C825T Polymorphism and the Occurrence of Cardiovascular Disease in Hypertensives: The Nord-Trondelag Health Study (HUNT).
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Bianchini, Federico;
Birkeland, Even;
Bösl, Korbinian;
Gade, Alexandra;
Holmen, Oddgeir Lingaas;
Hu, Xian.
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Zenodo
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Undervisning
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Formidling
2018
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PosterRostami, Sina; Hoff, Mari; Brown, Matthew A.; Hveem, Kristian; Holmen, Oddgeir Lingaas; Videm, Vibeke. (2018) Risk association for ankylosing spondylitis using a genetic risk score combining 110 SNPs of genome-wide significance in the population-based HUNT study. EULAR EULAR Annual European Congress of Rheumatology , Amsterdam 2018-06-13 - 2018-06-16
2017
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PosterLyngbakken, Magnus Nakrem; Røsjø, Helge; Holmen, Oddgeir Lingaas; Dalen, Håvard; Hveem, Kristian; Omland, Torbjørn. (2017) Temporal Changes in Cardiac Troponin I and Risk of Cardiovascular Events in the General Population: The Nord-Trøndelag Health Study. American Heart Association American Heart Association Scientific Sessions 2017 , Anaheim 2017-11-11 - 2017-11-15
2016
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Vitenskapelig foredragLøset, Mari; Modalsli, Ellen Heilmann; Snekvik, Ingrid; Zhou, Wei; Chu, Yunhan; Gabrielsen, Maiken Elvestad. (2016) HUNTing for Genes that Affect Psoriasis in ~2,900 Cases and ~48,000 Controls. The 33rd Nordic Congress of Dermatology and Venereolgy 2016-04-27 - 2016-04-29
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PosterLyngbakken, Magnus Nakrem; Røsjø, Helge; Holmen, Oddgeir Lingaas; Dalen, Håvard; Hveem, Kristian; Omland, Torbjørn. (2016) Impact of smoking on circulating troponin I concentrations and cardiovascular events in the general population: The HUNT Study. European Society of Cardiologogy ESC2016 , Roma 2016-08-27 -
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Vitenskapelig foredragSolvin, Åshild Øksnevad; Modalsli, Ellen Heilmann; Snekvik, Ingrid; Gabrielsen, Maiken Elvestad; Holmen, Oddgeir Lingaas; Saunes, Marit. (2016) Establishing a biobank for gene expression studies of psoriasis. Frampeik , Bergen 2016-10-21 - 2016-10-23