Marte Singsås Dragset
Om
Min kjernekompetanse ligger i å lede banebrytende forskning og fremme innovasjon. Ved et av NTNU’s Sentre for Fremragende Forskning, CEMIR, er min oppgave å fremme forståelsen av bakterienes virulensstrategier og vert-patogen interaksjoner. Min ekspertise i å skaffe finansiering, veilede studenter og lede forskningsprosjekter understreker mitt engasjement for å bidra til folkehelse og vitenskapelig fremragende utvikling. Min rolle som prosjektleder hos GSK via Tres Cantos Open Lab Foundation fremhever mine evner til å lede industrielle forskningsprosjekter. Stillingen innebærer tverrfaglig samarbeid med fokus på å levere resultater. Ved å utnytte mine ekspertise innen molekylær mikrobiologi, cellebiologi og genetikk, er målet mitt at prosjektene jeg leder gir resultater av høyeste kvalitet for å drive forståelsen av infeksjonsbiologi og antimikrobiell resistens framover.
Jeg jobber med vert-patogen interaksjoner, med fokus på bakteriell virulens. Virulensfaktorer er bakterienes "våpen" for å forårsake sykdom. Jeg er spesielt interessert i mykobakterier, en slekt som inneholder medlemmer som forårsaker tuberkulose og tuberkulose-lignende sykdommer. Tuberkulose er nå verdens største smittsomme sykdomsårsaker, med rundt 1,5 millioner dødsfall årlig. Jeg fullførte min mastergrad ved Universitetet i Tromsø (molekylær eukaryot cellebiologi) og min doktorgrad ved Norges teknisk-naturvitenskapelige universitet (molekylær mikrobiologi). Jeg tilbrakte to år av min doktorgradsutdanning ved Harvard University i Boston, USA. Jeg var nylig på et tilsammen fireårig forskningsopphold ved Germans Trias i Pujol Research Institute utenfor Barcelona, Spania, hvor jeg jobbet med den vanlige bananfluen (Drosophila melanogaster) som vert for mykobakterielle infeksjoner.
Publikasjoner
2025
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Sivakumar, Niruja;
Fuentes, Esther;
Selvik, Linn-Karina M.;
Arch, Marta;
Ås, Christina Gabrielsen;
Cardona, Pere-Joan.
(2025)
Genome-wide phenotypic insights into mycobacterial virulence using Drosophila melanogaster | PLOS Pathogens.
PLoS Pathogens
Vitenskapelig artikkel
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Belardinelli, Juan M.;
Avanzi, Charlotte;
Martin, Kelsey E.;
Lam, Ha;
Dragset, Marte Singsås;
Wheat, William H..
(2025)
The DosR regulon of Mycobacterium avium and adaptation to hypoxia.
Frontiers in Cellular and Infection Microbiology
Vitenskapelig artikkel
2022
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Dragset, Marte Singsås;
Selvik, Linn-Karina M.;
Sivakumar, Niruja;
Fuentes, Esther;
Arch, Marta;
Ioerger, Thomas R..
(2022)
Drosophila melanogaster is a powerful host model to study mycobacterial virulence.
BioRxiv
Fagartikkel
-
Basson, Adelle;
Olaisen, Camilla;
Selvik, Linn-Karina M.;
Lyng, Randi Valsø;
Lysvand, Hilde;
Gidon, Alexandre.
(2022)
The Streptococcus agalactiae R3 surface protein is encoded by sar5.
PLOS ONE
Vitenskapelig artikkel
2020
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Basson, Adelle;
Afset, Jan Egil;
Dragset, Marte Singsås.
(2020)
Elucidating the gene encoding the R3 surface protein in Streptococcus agalactiae.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Mastergradsoppgave
2019
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Dragset, Marte Singsås;
Ioerger, Thomas R.;
Zhang, Yanjia;
Mærk, Mali;
Ginbot, Zekarias;
Sacchettini, James C..
(2019)
Genome-wide phenotypic profiling identifies and categorizes genes required for mycobacterial low iron fitness.
Scientific Reports
Vitenskapelig artikkel
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Dragset, Marte Singsås;
Ioerger, Thomas R.;
Loevenich, Maja;
Haug, Markus;
Sivakumar, Niruja;
Marstad, Anne.
(2019)
Global assessment of Mycobacterium avium subsp. hominissuis genetic requirement for growth and virulence.
mSystems
Vitenskapelig artikkel
2016
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Majumdar, Gaurav;
Mbau, Rendani;
Singh, Vinayak;
Warner, Digby;
Dragset, Marte Singsås;
Mukherjee, Raju.
(2016)
Genome-Wide Transposon Mutagenesis in Mycobacterium tuberculosis and Mycobacterium smegmatis.
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
2015
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Dragset, Marte Singsås;
Poce, Giovanna;
Alfonso, Salvatore;
Padilla-Benavides, Teresita;
Ioerger, Thomas R.;
Kaneko, Takushi.
(2015)
A novel antimycobacterial compound acts as an intracellular iron chelator.
Antimicrobial Agents and Chemotherapy
Vitenskapelig artikkel
-
Dragset, Marte Singsås;
Barczak, Amy K.;
Kannan, Nisha;
Mærk, Mali;
Flo, Trude Helen;
Valla, Svein.
(2015)
Benzoic Acid-Inducible Gene Expression in Mycobacteria.
PLOS ONE
Vitenskapelig artikkel
2014
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Siegrist, M. Sloan;
Steigedal, Magnus;
Ahmad, Rushdy;
Mehra, Alka;
Dragset, Marte Singsås;
Schuster, Brian M..
(2014)
Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition.
mBio
Vitenskapelig artikkel
2013
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Dragset, Marte Singsås.
(2013)
Riding the Ferrous Wheel: Identification and Study of Genes Involved in Mycobacterial Iron Acquisition.
Norges teknisk-naturvitenskapelige universitet
Doktoravhandlinger ved NTNU, 1503-8181 (2013:346)
Doktorgradsavhandling
2011
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Johannessen, Mona;
Walquist, Mari;
Gerits, Nancy;
Dragset, Marte Singsås;
Spang, Anne;
Moens, Ugo.
(2011)
BKV Agnoprotein Interacts with alpha-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP.
PLOS ONE
Vitenskapelig artikkel
2008
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Johannessen, Mona;
Myhre, marit renee;
Dragset, Marte Singsås;
Tummler, Conny;
Moens, Ugo.
(2008)
Phosphorylation of human polyomavirus BK agnoprotein at Ser-11 is mediated by PKC and has an important regulative function.
Virology
Vitenskapelig artikkel
2007
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Johannessen, Mona;
Delghandi, Marit Pedersen;
Rykx, An;
Dragset, Marte Singsås;
Vandenheede, Jackie R.;
Lint, Jo Van.
(2007)
Protein kinase D induces transcription through direct phosphorylation of the cAMP-response element-binding protein.
Journal of Biological Chemistry
Vitenskapelig artikkel
Tidsskriftspublikasjoner
-
Sivakumar, Niruja;
Fuentes, Esther;
Selvik, Linn-Karina M.;
Arch, Marta;
Ås, Christina Gabrielsen;
Cardona, Pere-Joan.
(2025)
Genome-wide phenotypic insights into mycobacterial virulence using Drosophila melanogaster | PLOS Pathogens.
PLoS Pathogens
Vitenskapelig artikkel
-
Belardinelli, Juan M.;
Avanzi, Charlotte;
Martin, Kelsey E.;
Lam, Ha;
Dragset, Marte Singsås;
Wheat, William H..
(2025)
The DosR regulon of Mycobacterium avium and adaptation to hypoxia.
Frontiers in Cellular and Infection Microbiology
Vitenskapelig artikkel
-
Dragset, Marte Singsås;
Selvik, Linn-Karina M.;
Sivakumar, Niruja;
Fuentes, Esther;
Arch, Marta;
Ioerger, Thomas R..
(2022)
Drosophila melanogaster is a powerful host model to study mycobacterial virulence.
BioRxiv
Fagartikkel
-
Basson, Adelle;
Olaisen, Camilla;
Selvik, Linn-Karina M.;
Lyng, Randi Valsø;
Lysvand, Hilde;
Gidon, Alexandre.
(2022)
The Streptococcus agalactiae R3 surface protein is encoded by sar5.
PLOS ONE
Vitenskapelig artikkel
-
Dragset, Marte Singsås;
Ioerger, Thomas R.;
Zhang, Yanjia;
Mærk, Mali;
Ginbot, Zekarias;
Sacchettini, James C..
(2019)
Genome-wide phenotypic profiling identifies and categorizes genes required for mycobacterial low iron fitness.
Scientific Reports
Vitenskapelig artikkel
-
Dragset, Marte Singsås;
Ioerger, Thomas R.;
Loevenich, Maja;
Haug, Markus;
Sivakumar, Niruja;
Marstad, Anne.
(2019)
Global assessment of Mycobacterium avium subsp. hominissuis genetic requirement for growth and virulence.
mSystems
Vitenskapelig artikkel
-
Dragset, Marte Singsås;
Poce, Giovanna;
Alfonso, Salvatore;
Padilla-Benavides, Teresita;
Ioerger, Thomas R.;
Kaneko, Takushi.
(2015)
A novel antimycobacterial compound acts as an intracellular iron chelator.
Antimicrobial Agents and Chemotherapy
Vitenskapelig artikkel
-
Dragset, Marte Singsås;
Barczak, Amy K.;
Kannan, Nisha;
Mærk, Mali;
Flo, Trude Helen;
Valla, Svein.
(2015)
Benzoic Acid-Inducible Gene Expression in Mycobacteria.
PLOS ONE
Vitenskapelig artikkel
-
Siegrist, M. Sloan;
Steigedal, Magnus;
Ahmad, Rushdy;
Mehra, Alka;
Dragset, Marte Singsås;
Schuster, Brian M..
(2014)
Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition.
mBio
Vitenskapelig artikkel
-
Johannessen, Mona;
Walquist, Mari;
Gerits, Nancy;
Dragset, Marte Singsås;
Spang, Anne;
Moens, Ugo.
(2011)
BKV Agnoprotein Interacts with alpha-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP.
PLOS ONE
Vitenskapelig artikkel
-
Johannessen, Mona;
Myhre, marit renee;
Dragset, Marte Singsås;
Tummler, Conny;
Moens, Ugo.
(2008)
Phosphorylation of human polyomavirus BK agnoprotein at Ser-11 is mediated by PKC and has an important regulative function.
Virology
Vitenskapelig artikkel
-
Johannessen, Mona;
Delghandi, Marit Pedersen;
Rykx, An;
Dragset, Marte Singsås;
Vandenheede, Jackie R.;
Lint, Jo Van.
(2007)
Protein kinase D induces transcription through direct phosphorylation of the cAMP-response element-binding protein.
Journal of Biological Chemistry
Vitenskapelig artikkel
Del av bok/rapport
-
Majumdar, Gaurav;
Mbau, Rendani;
Singh, Vinayak;
Warner, Digby;
Dragset, Marte Singsås;
Mukherjee, Raju.
(2016)
Genome-Wide Transposon Mutagenesis in Mycobacterium tuberculosis and Mycobacterium smegmatis.
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
Rapport
-
Basson, Adelle;
Afset, Jan Egil;
Dragset, Marte Singsås.
(2020)
Elucidating the gene encoding the R3 surface protein in Streptococcus agalactiae.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Mastergradsoppgave
-
Dragset, Marte Singsås.
(2013)
Riding the Ferrous Wheel: Identification and Study of Genes Involved in Mycobacterial Iron Acquisition.
Norges teknisk-naturvitenskapelige universitet
Doktoravhandlinger ved NTNU, 1503-8181 (2013:346)
Doktorgradsavhandling
Formidling
2025
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Faglig foredragHabjan, Eva; Dragset, Marte Singsås. (2025) A Novel Virulence Target against Tuberculosis. Winter Open Lab Seminar , Tres Cantos, Spain (+ online) 21.10.2025 -
2024
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Faglig foredragDragset, Marte Singsås. (2024) Virulens hos mykobakterier. Konferanse for tuberkulosekoordinatorer 8.-9. april 2024 , Trondheim 08.02.2024 - 09.04.2024
2023
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Vitenskapelig foredragSivakumar, Niruja; Dragset, Marte Singsås; Marstad, Anne; Flo, Trude Helen. (2023) A novel, multifunctional target in pathogenic mycobacteria. 33rd European Congress of Clinical Microbiology and Infectious Diseases , København 15.04.2023 - 18.04.2023
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PosterSivakumar, Niruja; Dragset, Marte Singsås; Marstad, Anne; Flo, Trude Helen. (2023) MFS1:A conserved virulence target in pathogenic mycobacteria. Tuberculosis Drug Discovery and Development , Barcelona 23.07.2023 - 28.07.2023
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Faglig foredragDragset, Marte Singsås; Selvik, Linn-Karina M.. (2023) Skolebesøk Fosen Videregående. Skolebesøk ved IKO; NTNU fra Fosen Videregående , NTNU, Trondheim 13.03.2023 -
2022
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Vitenskapelig foredragDragset, Marte Singsås; Selvik, Linn-Karina M.; Flo, Trude Helen; Steigedal, Magnus; Strand, Trine Aakvik; Ullmann, Sindre. (2022) The role of protease BlaR in mycobacterial low iron growth and virulence. Boston TB meeting 05.05.2022 -
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Vitenskapelig foredragDragset, Marte Singsås; Sivakumar, Niruja; Fuentes, Esther; Selvik, Linn-Karina M.; Arch, Marta; Cardona, Pere Joan. (2022) Drosophila melanogaster as a model to study mycobacterial host-pathogen interactions. EMBO Workshop on Tuberculosis 2022 , Paris 12.09.2022 - 16.09.2022
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PosterBasson, Adelle; Olaisen, Camilla; Selvik, Linn-Karina M.; Lyng, Randi Valsø; Lysvand, Hilde; Gidon, Alexandre. (2022) The Streptococcus agalactiae R3 surface protein is encoded by sar5. The 2022 Lancefield International Symposium on Streptococci and Streptococcal Diseases , Stockholm 07.06.2022 - 10.06.2022
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Vitenskapelig foredragDragset, Marte Singsås; Selvik, Linn-Karina M.; Flo, Trude Helen; Steigedal, Magnus; Strand, Trine Aakvik; Ullmann, Sindre. (2022) Disarm virulence and reduce resistance - in one go? Novel potential targets against tuberculosis. Norwegian Consortium for Microbial Genomics Meeting 2022 , Norwegian Institute of Public Health 08.12.2022 - 08.12.2022
2021
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Vitenskapelig foredragDragset, Marte Singsås. (2021) "Novel mycobacterial virulence factors and their potential in TB treatment". Glaxo Smith Klein R&D seminar , Madrid 20.01.2021 - 20.01.2021
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Vitenskapelig foredragSivakumar, Niruja; Dragset, Marte Singsås; Haug, Markus; Marstad, Anne; Cardona, Pere Joan; Flo, Trude Helen. (2021) A novel, multifunctional target in mycobacterial drug discovery. IBA Annual Meeting , Oslo 01.11.2021 - 02.11.2021
2020
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Vitenskapelig foredragFlo, Trude Helen; Gidon, Alexandre; Mediaas, Sindre Dahl; Dragset, Marte Singsås. (2020) AMR in mycobacterial infections and the search for new treatments. AMR-BRIDGE workshop «The need for new antibiotics» , Jægtvolden 13.10.2020 - 14.10.2020
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Vitenskapelig foredragDragset, Marte Singsås. (2020) Mycobacterial virulence genes in Drosophila melanogaster. The annual IBA meeting 2020 , Trondheim (online) 26.10.2020 - 27.10.2020
2019
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Vitenskapelig foredragDragset, Marte Singsås. (2019) Novel Mycobacterial Virulence Genes. TTA - Turning the Tide of Antimicrobial Resistance , Oslo 17.11.2019 - 21.11.2019
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Vitenskapelig foredragDragset, Marte Singsås. (2019) Screening for Mycobacterial Virulence Genes using Drosophila melanogaster. Coffee Talk at IGTP , Barcelona 10.04.2019 - 10.04.2019
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PosterSivakumar, Niruja; Dragset, Marte Singsås; Ioerger, Thomas R.; Loevenich, Maja; Haug, Markus; Marstad, Anne. (2019) Identification of novel virulence mechanisms in pathogenic mycobacteria. Conference on Molecular Mechanisms of Inflammation , Trondheim 03.06.2019 - 06.06.2019
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Vitenskapelig foredragSivakumar, Niruja; Dragset, Marte Singsås; Ioerger, Thomas R.; Loevenich, Maja; Haug, Markus; Marstad, Anne. (2019) Global assessment of Mycobacterium avium subspecies hominissuis genetic requirement for virulence. Norwegian Biochemical Society 55th Contact Meeting , Røros 24.01.2019 - 27.01.2019
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PosterDragset, Marte Singsås; Ioerger, Thomas R.; Cardona, Pere-Joan. (2019) Drosophila melanogaster as a Host Model to Study Mycobacterial Virulence. The Second Conference of Molecular Mechanisms of Inflammation , Trondheim 03.06.2019 - 06.06.2019
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PosterDragset, Marte Singsås; Ioerger, Thomas R.; Cardona, Pere-Joan. (2019) Drosophila melanogaster as a Host Model to Study Mycobacterial Virulence. Gordon Research Conference on Tuberculosis Drug Discovery and Development , Casterdefells 07.07.2019 - 12.07.2019
2018
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Vitenskapelig foredragDragset, Marte Singsås. (2018) Screening for virulence genes using Drosophila melanogaster. BilboTB , CIC bioGUNE, Derio 17.09.2018 - 19.09.2018
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Vitenskapelig foredragDragset, Marte Singsås. (2018) Identification of Virulence Genes by Transposon Insertion Sequencing. Coffee Talk (weekly seminars) , Badalona, Barcelona 11.04.2018 - 11.04.2018
2017
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Vitenskapelig foredragDragset, Marte Singsås. (2017) Transposon Insertion Sequencing to Identify Mycobacterial Virulence Genes. CEMIR Taormina Retreat , Taormina, Sicily 16.10.2017 - 19.10.2017
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Vitenskapelig foredragDragset, Marte Singsås. (2017) Screening for Mycobacterial Virulence Genes by Transposon Insertions Sequencing. MycoZAR 2017 , Caixa Forum (Calle José Anselmo Clavé, 4, 50004, Zaragoza) 28.09.2017 - 29.09.2017
2016
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Vitenskapelig foredragDragset, Marte Singsås. (2016) The Battle for Iron between Mycobacteria and the Host. Seminar series at the Medical Faculty , Tenerife 04.11.2016 - 04.11.2016
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PosterDragset, Marte Singsås; Ioerger, Thomas R.; Helland, Maja; Haug, Markus; Marstad, Anne; Klinkenberg, Geir. (2016) A mutant toolbox to study mycobacterial infections. CONFERENCE ON MOLECULAR MECHANISMS OF INFLAMMATION , Trondheim 30.05.2016 - 02.06.2016
2014
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PosterDragset, Marte Singsås; Zhang, Yanjia; Ioerger, Thomas; Pritchard, Justin; Flo, Trude Helen; Sacchettini, James. (2014) Identification of Mycobacterial Iron Uptake Genes. 9th International Conference on the Pathogenesis of Mycobacterial Infections 26.06.2014 - 29.06.2014
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Faglig foredragDragset, Marte Singsås; Steigedal, Magnus; Flo, Trude Helen; Valla, Svein. (2014) Identification of Genes Involved in Mycobacterial Iron Uptake. NBS Contact Meeting, minisymposium , Røros 23.01.2014 - 23.01.2014
2013
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Vitenskapelig foredragDragset, Marte Singsås; Steigedal, Magnus; Valla, Svein; Flo, Trude Helen. (2013) Riding the Ferrous Wheel: Identification and Study of Genes Involved in Mycobacterial Iron Acquisition. Department seminar at the Department of Biotechnology , Trondheim 13.11.2013 - 13.11.2013
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Vitenskapelig foredragSteigedal, Magnus; Siegrist, Sloan; Dragset, Marte Singsås; Haug, Markus; Ahmad, Rushdy; Rubin, Eric J. (2013) EspG of Esx-3 contributes to Mycobactin-mediated Iron Acquisition and Protein secretion in Mycobacteria. Norwegian Bichemical Society Contact Meeting 2013 , Lillehammer 31.01.2013 - 03.02.2013
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PosterSteigedal, Magnus; Siegrist, Sloan; Dragset, Marte Singsås; Haug, Markus; Ahmad, Rushdy; Rubin, Eric J. (2013) EspG Contributes to Mycobactin-Mediated Iron Acquisition and Protein Secretion in Mycobacteria. Keystone symposia: Tuberculosis: Understanding the enemy 13.03.2013 - 18.03.2013
2012
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Faglig foredragSteigedal, Magnus; Haug, Markus; Halaas, Øyvind; Marstad, Anne; Dragset, Marte Singsås; Awuh, Jane Atesoh. (2012) Tuberkulose tar millioner av liv. Kan vi finne en løsning?. Forskningsdagene: Forsker til lunsj , Veterinærinstituttet 28.09.2012 - 28.09.2012
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Faglig foredragSteigedal, Magnus; Dragset, Marte Singsås; Haug, Markus; Awuh, Jane Atesoh; Halaas, Øyvind; Marstad, Anne. (2012) Tuberkulose tar millioner av liv. Kan vi finne en løsning?. Forskningsdagene: Forsker til lunsj , BUP Saupstad 24.10.2012 - 24.10.2012
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Vitenskapelig foredragSteigedal, Magnus; Flo, Trude Helen; Haug, Markus; Dragset, Marte Singsås; Awuh, Jane Atesoh; Halaas, Øyvind. (2012) Iron uptake in mycobacteria: Searching for novel drug targets. Department seminar at the Department of Biotechnology , Trondheim 18.04.2012 - 18.04.2012
2009
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PosterDragset, Marte Singsås; Steigedal, Magnus; Flo, Trude Helen; Valla, Svein. (2009) Searching future therapies for tuberculosis: Identification of genes involved in /Mycobacterium avium/ intracellular survival in macrophages. NBS kontaktmøte , Røros 29.01.2009 - 01.02.2009