Magnus Steigedal
Bakgrunn og aktiviteter
Jeg er instituttleder for Institutt for klinisk og molekylær medisin (IKOM). Tidligere ledet jeg NTNUs tematiske satsingsområde Helse, velferd og teknologi. Som forsker er jeg interessert i å undersøke hvordan mikroorganismer klarer å infisere mennesker og vil bruke kunnskapen til å finne nye mål for antibiotika, særlig mot tuberkulose.
Viktigste ansvar og oppgaver
- Leder for IKOM
Bakgrunn, utdrag
- 2015-2017 Prosjektleder forskerprosjekt Joint Programing Initative (JPIAMR)
- 2014–2021 Leder NTNUs tematiske satsingsområde Helse, velferd og teknologi
- 2013–2018 Prosjektleder forskerprosjekt Forskningsrådets program GLOBVAC
- 2012– Forsker Senter for molekylær inflammasjonsforskning (CEMIR), et senter for fremragende forskning, og Institutt for kreftforskning og molekylær medisin, begge NTNU
- 2012–2015 Prosjektleder forskningsprosjekt NTNU/Helse Midt-Norge RHF
- 2010–2011 Forsker Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, USA
- 2007–2012 Co-Prosjektleder forskningsprosjekt NTNU/Helse Midt-Norge RHF
- 2006–2012 Postdok Institutt for kreftforskning og molekylær medisin, NTNU
- 2001–2006 Doktorgradsstudent Institutt for bioteknologi, NTNU
Vitenskapelig, faglig og kunstnerisk arbeid
Et utvalg av nyere tidsskriftspublikasjoner, kunstneriske produksjoner, bok, inklusiv bokdeler og rapport-del. Se alle publikasjoner i databasen
Tidsskriftspublikasjoner
- (2020) Mycobacterium smegmatis Vaccine Vector Elicits CD4+ Th17 and CD8+ Tc17 T Cells With Therapeutic Potential to Infections With Mycobacterium avium. Frontiers in Immunology. vol. 11.
- (2019) Global assessment of Mycobacterium avium subsp. hominissuis genetic requirement for growth and virulence. mSystems. vol. 4 (6).
- (2019) Genome-wide phenotypic profiling identifies and categorizes genes required for mycobacterial low iron fitness. Scientific Reports. vol. 9:11394.
- (2019) Genetic Variation/Evolution and Differential Host Responses Resulting from In-Patient Adaptation of Mycobacterium avium. Infection and Immunity. vol. 87 (4).
- (2015) Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages. Proceedings of the National Academy of Sciences of the United States of America. vol. 112 (31).
- (2015) Benzoic Acid-Inducible Gene Expression in Mycobacteria. PLOS ONE. vol. 10 (9).
- (2015) A novel antimycobacterial compound acts as an intracellular iron chelator. Antimicrobial Agents and Chemotherapy. vol. 59 (4).
- (2014) Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition. mBio. vol. 5 (3:e01073-14).
- (2014) Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection. Journal of Immunology. vol. 193 (12).
- (2013) Dynamics of immune effector mechanisms during infection with Mycobacterium aviumin C57BL/6 mice. Immunology. vol. 140 (2).
- (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases. vol. 201 (5).
- (2008) The Azotobacter vinelandii AlgE mannuronan C-5-epimerase family is essential for the in vivo control of alginate monomer composition and for functional cyst formation. Environmental Microbiology. vol. 10 (7).
- (2008) The Acinetobacter sp chnB promoter together with its cognate positive regulator ChnR is an attractive new candidate for metabolic engineering applications in bacteria. Metabolic Engineering. vol. 10 (2).
- (2006) Identification and characterization of an Azotobacter vinelandii type I secretion system responsible for export of the AlgE-Type mannuronan C-5-epimerases. Journal of Bacteriology. vol. 188 (15).
Rapport/avhandling
- (2006) The Azotobacter vinelandii mannuronan C5-epimerases: their biological functions and new tools useful for their future in vivo biotechnological application. 2006. ISBN 82-471-7775-7.
- (2001) Epimerisering av alginat kan være knyttet til ekstrakromosomalt DNA i Azotobacter chroococcum. 2001.