2025

• Resell, Mathilde Victoria; Rabben, Hanne-Line; Sharma, Animesh; Hagen, Lars; Hoang, Linh; Tostrup-Skogaker, Nan. (2025) PROTEOMICS PROFILING OF RESEARCH MODELS FOR STUDYING PANCREATIC DUCTAL ADENOCARCINOMA. Scientific Data
  Fagartikkel
• Iveland, Tobias Solli; Hagen, Lars; Sousa, Mirta; Liabakk, Nina-Beate; Aas, Per Arne; Sharma, Animesh. (2025) Cytotoxic mechanisms of pemetrexed and HDAC inhibition in non-small cell lung cancer cells involving ribonucleotides in DNA. Scientific Reports
  Vitenskapelig artikkel
• Resell, Mathilde Victoria; Graarud, Elisabeth Pimpisa; Rabben, Hanne-Line; Sharma, Animesh; Hagen, Lars; Hoang, Linh. (2025) Knowledge Discovery in Datasets of Proteomics by Systems Modeling in Translational Research on Pancreatic Cancer. bioRxiv
  Vitenskapelig artikkel
• Resell, Mathilde Victoria; Rabben, Hanne-Line; Sharma, Animesh; Hagen, Lars; Hoang, Linh; Tostrup-Skogaker, Nan. (2025) Proteomics profiling of research models for studying pancreatic ductal adenocarcinoma. Scientific Data
  Fagartikkel

2024

• Zhao, Chun Mei; Rabben, Hanne-Line; Resell, Mathilde Victoria; Ianevski, Aleksandr; Sharma, Animesh; Hagen, Lars. (2024) INHIBITION OF EXOSOMES SUPPRESSES THE PROGRESSION OF PANCREATIC DUCTAL ADENOCARCINOMA: A STUDY USING MOUSE MODELS AND HUMAN ORGANOIDS. United European Gastroenterology Journal (UEG Journal)
  Fagartikkel
• Obermann, Tobias; Sakshaug, Teri Shearer; Kanagaraj, Vishnu Vignesh; Abentung, Andreas; Leal de Sousa, Mirta Mittelstedt; Hagen, Lars. (2024) Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH. Redox Biology
  Vitenskapelig artikkel
• Wang, Feng; Eikeland, Eline; Reidunsdatter, Randi Johansen; Hagen, Lars; Engstrøm, Monica Jernberg; Geisler, Jürgen. (2024) Quantification of multiple steroid hormones in serum and human breast cancer tissue by liquid chromatography-tandem mass spectrometry analysis. Frontiers in Oncology
  Vitenskapelig artikkel
• Berg, Sigrid Ravn; Demirovic, Aida; Sharma, Animesh; Hagen, Lars; Vågbø, Cathrine Broberg; Zatula, Alexey. (2024) Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens. Journal of Translational Medicine
  Vitenskapelig artikkel
• Farjami, Toktam; Sharma, Animesh; Hagen, Lars; Jensen, Ida-Johanne; Falch, Eva. (2024) Comparative study on composition and functional properties of brewer's spent grain proteins precipitated by citric acid and hydrochloric acid. Food Chemistry
  Vitenskapelig artikkel
• Swaminathan, Priyanka; Klingstedt, Therése; Theologidis, Vasileios; Gram, Hjalte; Larsson, Johan; Hagen, Lars. (2024) In Vitro Cell Model Investigation of Alpha-Synuclein Aggregate Morphology Using Spectroscopic Imaging. International Journal of Molecular Sciences
  Vitenskapelig artikkel

2023

• Starheim, Eirin Johannessen; Ravlo, Erlend; Schjølberg, Jørn-Ove; Solvang, Vanessa; Wang, Wei; Scrimgeour, Nathan Robert. (2023) NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA. Scientific Reports
  Vitenskapelig artikkel
• Resell, Mathilde Victoria; Rabben, Hanne-Line; Amrutkar, Manoj; Hagen, Lars; Batra, Surinder K.; Verbeke, Caroline Sophie. (2023) Mo1138 COMPARATIVE PROTEOMICS REVEALS TRANSLATIONAL POTENTIAL OF TARGETS FOR PANCREATIC DUCTAL ADENOCARCINOMA. Gastroenterology
  Sammendrag/abstract
• Wang, Feng; Giskeødegård, Guro F.; Skarra, Sissel; Engstrøm, Monica Jernberg; Hagen, Lars; Geisler, Jürgen. (2023) Association of serum cortisol and cortisone levels and risk of recurrence after endocrine treatment in breast cancer. Clinical and Experimental Medicine
  Vitenskapelig artikkel
• Gederaas, Odrun Arna; Sharma, Animesh; Mbarak, Saide; Sporsheim, Bjørnar; Høgset, Anders; Bogoeva, Vanya. (2023) Proteomic analysis reveals mechanisms underlying increased efficacy of bleomycin by photochemical internalization in bladder cancer cells. Molecular Omics
  Vitenskapelig artikkel
• Ravlo, Erlend; Sousa, Mirta; Andresen, Lise Lima; Holberg-Petersen, Mona; Klundby, Ingvild; Aas, Per Arne. (2023) A fast, low-cost, robust and high-throughput method for viral nucleic acid isolation based on NAxtra magnetic nanoparticles. Scientific Reports
  Vitenskapelig artikkel

2022

• Pinto, Sneha M.; Subbannayya, Yashwanth; Kim, Hera; Hagen, Lars; Górna, Maria W; Nieminen, Anni I.. (2022) Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells. iScience
  Vitenskapelig artikkel
• Høiem, Therese Stork; Andersen, Maria Karoline; Martin-Lorenzo, Marta; Longuespée, Rémi; Claes, Britt S.R.; Nordborg, Anna. (2022) An optimized MALDI MSI protocol for spatial detection of tryptic peptides in fresh frozen prostate tissue. Proteomics
  Vitenskapelig artikkel

2021

• Wang, Qiong; Karvelsson, Sigurdur Trausti; Johannsson, Freyr; Vilhjalmsson, Arnar Ingi; Hagen, Lars; Fonseca, Davi de Miranda. (2021) UDP-glucose dehydrogenase expression is upregulated following EMT and differentially affects intracellular glycerophosphocholine and acetylaspartate levels in breast mesenchymal cell lines. Molecular Oncology
  Vitenskapelig artikkel
• Kavli, Bodil Merete; Iveland, Tobias Solli; Buchinger, Edith; Hagen, Lars; Liabakk, Nina-Beate; Aas, Per Arne. (2021) RPA2 winged-helix domain facilitates UNG-mediated removal of uracil from ssDNA; implications for repair of mutagenic uracil at the replication fork. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel
• Iveland, Tobias S.; Hagen, Lars; Sharma, Animesh; Sousa, Mirta M. L.; Sarno, Antonio; Wollen, Kristian Lied. (2021) Correction to: HDACi mediate UNG2 depletion, dysregulated genomic uracil and altered expression of oncoproteins and tumor suppressors in B- and T-cell lines (Journal of Translational Medicine, (2020), 18, 1, (159), 10.1186/s12967-020-02318-8). Journal of Translational Medicine
  Errata
• Alves, Christiano R. R.; Eichelberger, Eric J.; das Neves, Willian; Ribeiro, Márcio A. C.; Bechara, Luiz R.G.; Voltarelli, Vanessa A.. (2021) Cancer-induced muscle atrophy is determined by intrinsic muscle oxidative capacity. The FASEB Journal
  Vitenskapelig artikkel
• Steen, Kristian Wollen; Hagen, Lars; Vågbø, Cathrine Broberg; Rabe, Renana; Iveland, Tobias Solli; Aas, Per Arne. (2021) ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA. Journal of Translational Medicine
  Vitenskapelig artikkel

2020

• Ianevski, Aleksandr; Yao, Rouan; Fenstad, Mona H.; Biza, Svetlana; Zusinaite, Eva; Reisberg, Tuuli. (2020) Potential Antiviral Options against SARS-CoV-2 Infection. Viruses. Viruses
  Vitenskapelig artikkel
• Iveland, Tobias Solli; Hagen, Lars; Sharma, Animesh; Sousa, Mirta; Sarno, Antonio; Wollen, Kristian Lied. (2020) HDACi Mediate UNG2 Depletion, Dysregulated Genomic Uracil and Altered Expression of Oncoproteins and Tumor Suppressors in B- And T-cell Lines. Journal of Translational Medicine
  Vitenskapelig artikkel
• Alves, Christiano R. R.; des Neves, Willian; de Almeida, Ney R; Eichelberger, Eric J; Jannig, Paulo R.; Voltarelli, Vanessa A. (2020) Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN. Molecular Metabolism
  Vitenskapelig artikkel

2019

• Toraskar, Jimita Prashant; Norvoll Magnussen, Synnøve; Hagen, Lars; Sharma, Animesh; Hoang, Linh; Bjørkøy, Geir. (2019) A Novel Truncated Form of Nephronectin Is Present in Small Extracellular Vesicles Isolated from 66cl4 Cells. Journal of Proteome Research
  Vitenskapelig artikkel
• Sarno, Antonio; Lundbæk, Marie Benner; Liabakk, Nina-Beate; Aas, Per Arne; Mjelle, Robin; Hagen, Lars. (2019) Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel
• Macur, Katarzyna; Hagen, Lars; Ciesielski, Tomasz Maciej; Konieczna, Lucyna; Skokowski, Jaroslaw; Jenssen, Bjørn Munro. (2019) A targeted mass spectrometry immunoassay to quantify osteopontin in fresh-frozen breast tumors and adjacent normal breast tissues. Journal of Proteomics
  Vitenskapelig artikkel
• Berges, Natalia; Nawaz, Meh Sameen; Dahl, Tuva Børresdatter; Hagen, Lars; Bjørås, Magnar; Lærdahl, Jon Kristen. (2019) Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform. PLOS ONE
  Vitenskapelig artikkel

2018

• Moe, Nogaye; Hagen, Lars; Gederaas, Odrun Arna. (2018) Bleomycin in endosomes after photochemical internalization (PCI) in bladder cancer cells (AY27). Nogaye Moe
  Mastergradsoppgave
• Souza, Rodrigo W. A.; Alves, Christiano R. R.; Medeiros, Alessandra; Rolim, Natale Pinheiro Lage; Silva, Gustavo Jose Justo; Moreira, Jose Bianco Nascimento. (2018) Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity. Scientific Reports
  Vitenskapelig artikkel

2017

• Orjahan, Sayed; Gederaas, Odrun Arna; Hagen, Lars. (2017) Endosomal uptake of Doxorubicin in cancer cells after photochemical internalization. Orjahan Sayed
  Mastergradsoppgave

2016

• Kanamazina, Yusuf; Gederaas, Odrun Arna; Hagen, Lars. (2016) Proteomic analysis of endosomes after photochemical internalization - establishment of new protocol for rat bladder cancer cell line (AY27). Tapir Akademisk Forlag Tapir Akademisk Forlag
  Mastergradsoppgave
• Saide, Mbarak; Gederaas, Odrun Arna; Hagen, Lars. (2016) Photochemical internalization by cancer cell lines from rat glioma(F98) and bladder (AY27) and its proteome analyses. Tapir Akademisk Forlag Tapir Akademisk Forlag
  Mastergradsoppgave
• Helander, Linda; Sharma, Animesh; Krokan, Hans Einar; Plaetzer, Kristjan; Krammer, Barbara; Tortik, Nicole. (2016) Photodynamic treatment with hexyl-aminolevulinate mediates reversible thiol oxidation in core oxidative stress signaling proteins. Molecular Biosystems
  Vitenskapelig artikkel

2015

• Lysvand, Hilde; Helland, Ronny; Hagen, Lars; Slupphaug, Geir; Iversen, Ole-Jan. (2015) Psoriasis pathogenesis – Pso p27 constitutes a compact structure forming large aggregates. Biochemistry and Biophysics Reports
  Vitenskapelig artikkel
• Kataya, Amr Ramzy Abass; Heidari Ahootapeh, Behzad; Hagen, Lars; Kommedal, Roald; Slupphaug, Geir; Lillo, Cathrine. (2015) Protein phosphatase 2A holoenzyme is targeted to peroxisomes by piggybacking and positively affects peroxisomal β-oxidation. Plant Physiology
  Vitenskapelig artikkel
• Baglo, Yan; Qian, Peng; Hagen, Lars; Berg, Kristian; Høgset, Anders; Drabløs, Finn. (2015) Studies of the photosensitizer disulfonated meso-tetraphenyl chlorin in an orthotopic rat bladder tumor model. Photodiagnosis and Photodynamic Therapy
  Vitenskapelig artikkel
• Kataya, Amr Ramzy Abass; Heidari, Behzad; Hagen, Lars; Kommedal, Roald; Slupphaug, Geir; Lillo, Cathrine. (2015) Supplemental materials for: Protein phosphatase 2A holoenzyme is targeted to peroxisomes by piggybacking and positively affects peroxisomal β-oxidation. Plant Physiology
  Vitenskapelig artikkel

2014

• Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Abdollahi, Pegah; Vansemb, Esten; Hagen, Lars; Baranowska, Katarzyna Anna. (2014) PRL-3 Mediates Survival of Primary Myeloma Cells. Blood
  Sammendrag/abstract
• Hagen, Lars; Sharma, Animesh; Aas, Per Arne; Slupphaug, Geir. (2014) Off-target responses in the HeLa proteome subsequent to transient plasmid-mediated transfection. Biochimica et Biophysica Acta - Proteins and Proteomics
  Vitenskapelig artikkel
• Lysvand, Hilde; Hagen, Lars; Klubicka, Lidija; Slupphaug, Geir; Iversen, Ole-Jan. (2014) Psoriasis pathogenesis - Pso p27 is generated from SCCA1 with chymase. Biochimica et Biophysica Acta - Molecular Basis of Disease
  Vitenskapelig artikkel
• Baglo, Yan; Hagen, Lars; Høgset, Anders; Drabløs, Finn; Otterlei, Marit; Gederaas, Odrun Arna. (2014) Enhanced efficacy of bleomycin in bladder cancer cells by photochemical internalization. BioMed Research International
  Vitenskapelig artikkel

2013

• Galashevskaya, Anastasia; Sarno, Antonio; Vågbø, Cathrine Broberg; Aas, Per Arne; Hagen, Lars; Slupphaug, Geir. (2013) A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported. DNA Repair
  Vitenskapelig artikkel

2012

• Torseth, Kathrin; Doseth, Berit; Hagen, Lars; Olaisen, Camilla; Liabakk, Nina-Beate; Græsmann, Heidi. (2012) The UNG2 Arg88Cys variant abrogates RPA-mediated recruitment of UNG2 to single-stranded DNA. DNA Repair
  Vitenskapelig artikkel

2011

• Kristiansen, Erlend; Ramløv, Hans; Højrup, Peter; Pedersen, Sindre Andre; Hagen, Lars; Zachariassen, Karl Erik. (2011) Structural characteristics of a novel antifreeze protein from the longhorn beetle Rhagium inquisitor. Insect Biochemistry and Molecular Biology
  Vitenskapelig artikkel
• Iversen, Ole-Jan; Lysvand, Hilde; Hagen, Lars. (2011) The autoantigen Pso p27: A post-translational modification of SCCA molecules. Autoimmunity
  Vitenskapelig artikkel
• Sousa, Mirta; Steen, Kristian Wollen; Hagen, Lars; Slupphaug, Geir. (2011) Antibody cross-linking and target elution protocols used for immunoprecipitation significantly modulate signal-to noise ratio in downstream 2D-PAGE analysis. Proteome Science
  Vitenskapelig artikkel
• Baglo, Yan; Sousa, Mirta; Slupphaug, Geir; Hagen, Lars; Håvåg, Sissel; Helander, Linda. (2011) Photodynamic therapy with hexyl aminolevulinate induces carbonylation, posttranslational modifications and changed expression of proteins in cell survival and cell death pathways. Photochemical and Photobiological Sciences
  Vitenskapelig artikkel

2010

• Felberg, Hanne Solvang; Hagen, Lars; Slupphaug, Geir; Batista, Irineu; Nunes, Maria Leonora; Olsen, Ragnar Ludvig. (2010) Partial characterisation of gelatinolytic activities in herring (Clupea harengus) and sardine (Sardina pilchardus) possibly involved in post-mortem autolysis of ventral muscle. Food Chemistry
  Vitenskapelig artikkel
• Bergstrøm, Bjarte Aune; Johnsen, Ingvild Bjellmo; Nguyen, Thank Thuy Thi; Hagen, Lars; Slupphaug, Geir; Thommesen, Liv. (2010) Identification of a Novel in Vivo Virus-targeted Phosphorylation Site in Interferon Regulatory Factor-3 (IRF3). Journal of Biological Chemistry
  Vitenskapelig artikkel

2009

• Visnes, Torkild; Doseth, Berit; Pettersen, Henrik Sahlin; Hagen, Lars; Sousa, Mirta; Akbari, Mansour. (2009) Uracil in DNA and its processing by different DNA glycosylases. Philosophical Transactions of the Royal Society of London. Biological Sciences
  Vitenskapelig oversiktsartikkel/review

2008

• Westbye, Marianne; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Talstad, Vivi A; Kavli, Bodil Merete. (2008) Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Visnes, Torkild; Akbari, Mansour; Hagen, Lars; Slupphaug, Geir; Krokan, Hans Einar. (2008) The rate of base excision repair of uracil is controlled by the initiating glycosylase. DNA Repair
  Vitenskapelig artikkel
• Hagen, Lars; Kavli, Bodil Merete; Sousa, Mirta; Torseth, Kathrin; Liabakk, Nina-Beate; Sundheim, Ottar. (2008) Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA. EMBO Journal
  Vitenskapelig artikkel
• Hagen, Lars. (2008) Regulation of DNA base excision repair by protein interactions and post translational modifications. NTNU
  Doktorgradsavhandling

2007

• Krokan, Hans Einar; Kavli, Bodil Merete; Akbari, Mansour; Visnes, Torkild; Pettersen, Henrik P Sahlin; Sundheim, Ottar. (2007) Repair og uracil in DNA by UNG2 and SMUG1 - an update. DNA Repair
  Sammendrag/abstract

2006

• Hagen, Lars; Diaz, Javier Pena; Kavli, Bodil Merete; Otterlei, Marit; Slupphaug, Geir; Krokan, Hans Einar. (2006) Genomic uracil and human disease. Experimental Cell Research
  Vitenskapelig oversiktsartikkel/review

2005

• Kristiansen, Erlend; Ramløv, Hans; Hagen, Lars; Pedersen, Sindre Andre; Andersen, Rolf Arvid; Zachariassen, Karl Erik. (2005) Isolation and characterization of hemolymph antifreeze proteins from larvae of the longhorn beetle Rhagium inquisitor (L.). Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology
  Vitenskapelig artikkel

2004

• Christiansen, Per; Aaberg, Marit; Berg, Anne; Gamstøbakk, Silje; Hagen, Lars; Hatling, Lillian. (2004) Regional statsstøtte og EØS-reglane : utgreiing frå eit utval nedsett ved kronprinsregentens resolusjon 27. februar 2004 : avgjeven til Kommunal- og regionaldepartementet 23. august 2004. NOU - Norges offentlige utredninger (2004:15)
  Fagbok
• Akbari, Mansour; Otterlei, Marit; Diaz, Javier Pena; Aas, Per Arne; Kavli, Bodil; Liabakk, Nina-Beate. (2004) Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells. Nucleic Acids Research (NAR)
  Vitenskapelig artikkel

2003

• Kvalsvik, Oddvar; Borchgrevink, Petter Chr.; Hagen, Lars; Dale, Ola. (2003) Randomized, double-blind, placebo-controlled study of the effect of rectal paracetamol on morphine consumption after abdominal hysterectomy. Acta Anaesthesiologica Scandinavica
  Vitenskapelig artikkel

2002

• Holthe, Monica; Klepstad, Pål; Zahlsen, Kolbjørn; Borchgrevink, Petter Chr.; Hagen, Lars; Dale, Ola. (2002) Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1a1*28 polymorphisms in cancer patients on chronic morphine therapy. European Journal of Clinical Pharmacology
  Vitenskapelig artikkel
• Brautaset, Trygve; Bruheim, Per; Sletta, Håvard; Hagen, Lars; Ellingsen, Trond E.; Strøm, Arne Reidar. (2002) Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455. Chemistry and Biology
  Vitenskapelig artikkel
• Kavli, Bodil; Sundheim, Ottar; Akbari, Mansour; Otterlei, Marit; Nilsen, Hilde; Skorpen, Frank. (2002) hUNG2 is the major repair enzyme for removal of uracil from U:A matchers,U:G mismatches and U in single stranded DNA, with SMUG1 as a broad specificity backup. Journal of Biological Chemistry
  Vitenskapelig artikkel