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  1. Ansatte

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Kristine Misund

Last ned pressefoto
Last ned pressefoto
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Kristine Misund

Forsker
Institutt for klinisk og molekylær medisin

kristine.misund@ntnu.no
73598552 72825286 Gastrosenteret, Øya, Prinsesse Kristinas gate 1
Cancer Genomics Multiple Myeloma - You Tube
Om Publikasjoner Undervisning Formidling

Om

Jobber som forsker ved Senter for Myelomforskning ved Institutt for klinisk og molekylær medisin.

Vi forsker på Myelomatose, som er en kreftform som oppstår i de antistoff produserende plasmacellene i beinmargen. Dette er en type blodkreft som rammer ca. 400 personer i Norge hvert år. Hovedfokuset i min forskning, er på det å undersøke og forstå de genetiske og molekylære endringene som skjer med kreftcellene fra diagnose tidspunktet og til utviklingen av en tumor som er resistent mot medikamenter. Vi prøver også å forstå hvorfor noen lever lenge med sykdommen mens andre har en aggressiv sykdom, og prøver å finne nye biomarkører for dette, ved å undersøke både kreftceller og de omkringliggende cellene. Vi bruker NGS sekvensering, CyTOF analyser, i tillegg til veletablerte cellebiologiske metoder. 

 

Publikasjoner

  • Kronologisk
  • Etter kategori
  • Se alle publikasjoner i Cristin

2025

  • Mestvedt, Ingvild Bergdal; Menu, Eline; Misund, Kristine; Slørdahl, Tobias Schmidt; Rasheed, Kashif; Wolowczyk, Camilla Izabel. (2025) Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation. bioRxiv
    Vitenskapelig artikkel
  • Behsen, Alenka Djarmila; Vandsemb, Esten Nymoen; Slørdahl, Tobias Schmidt; Dybkær, Karen; Jakobsen, Maja Zimmer; Kashif, Muhammad. (2025) T cell phenotype and clonality changes in myeloma patients with short overall survival. JCI Insight
    Vitenskapelig artikkel

2024

  • Berg, Sigrid Ravn; Demirovic, Aida; Sharma, Animesh; Hagen, Lars; Vågbø, Cathrine Broberg; Zatula, Alexey. (2024) Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens. Journal of Translational Medicine
    Vitenskapelig artikkel
  • Behsen, Alenka Djarmila; Holien, Toril; Micci, Francesca; Rye, Morten Beck; Rasmussen, Jenny Malm; Andersen, Kristin. (2024) Cell surface marker heterogeneity in human myeloma cell lines for modeling of disease and therapy. Scientific Reports
    Vitenskapelig artikkel
  • Jakobsen, Theresa; Pløen, Gro Grunnet; Behsen, Alenka Djarmila; Møller, Holger Jon; Plesner, Torben; Dybkær, Karen. (2024) The Prognostic Potential of circRNAs in Multiple Myeloma: Insights From Whole Bone Marrow and Purified Plasma Cells. Journal of Cellular and Molecular Medicine
    Vitenskapelig artikkel

2023

  • Aass, Kristin Roseth; Tryggestad, Synne Stokke; Mjelle, Robin; Kastnes, Martin Haugrud; Nedal, Tonje Marie Vikene; Misund, Kristine. (2023) IL-32 is induced by activation of toll-like receptors in multiple myeloma cells. Frontiers in Immunology
    Vitenskapelig artikkel
  • Behsen, Alenka Djarmila; Vandsemb, Esten Nymoen; Slørdahl, Tobias Schmidt; Hjorth-Hansen, Henrik; Quist-Paulsen, Petter; Misund, Kristine. (2023) A patient with minimal myeloma treatment who survived for 20 years. Haematologica
    Vitenskapelig artikkel

2022

  • Steiro, Ida Johnsen; Vandsemb, Esten Nymoen; Elsaadi, Samah; Misund, Kristine; Sponaas, Anne-Marit; Børset, Magne. (2022) The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells. OncoTarget
    Vitenskapelig artikkel
  • Giliberto, Mariaserena; Miranda Santana, Leonardo; Holien, Toril; Misund, Kristine; Nakken, Sigve; Vodak, Daniel. (2022) Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines. Frontiers in Oncology
    Vitenskapelig artikkel
  • Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco M.; Rustad, Even Holth; Sanders, Mathijs A.. (2022) Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence. Leukemia
    Vitenskapelig artikkel

2021

  • Håland, Erling; Moen, Ingrid Nyhus; Veidal, Elias; Hella, Hanne; Misund, Kristine; Slørdahl, Tobias Schmidt. (2021) TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan. OncoTarget
    Vitenskapelig artikkel
  • Aass, Kristin Roseth; Mjelle, Robin; Kastnes, Martin Haugrud; Tryggestad, Synne Stokke; van den Brink, Luca Mare; Roseth, Ingrid Aass. (2021) Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells. iScience
    Vitenskapelig artikkel
  • Sponaas, Anne-Marit; Waage, Anders; Vandsemb, Esten; Misund, Kristine; Børset, Magne; Sundan, Anders. (2021) Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?. Frontiers in Immunology
    Vitenskapelig oversiktsartikkel/review
  • Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved. (2021) Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma. The FASEB Journal
    Vitenskapelig artikkel

2020

  • Westhrin, Marita; Kovcic, Vlado; Zejian, Zhang; Moen, Siv Helen; Nedal, Tonje Marie Vikene; Bondt, Albert. (2020) Monoclonal immunoglobulins promote bone loss in multiple myeloma. Blood
    Vitenskapelig artikkel
  • Yang, Rui; Elsaadi, Samah; Misund, Kristine; Abdollahi, Pegah; Vandsemb, Esten; Moen, Siv Helen. (2020) Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade. Journal for ImmunoTherapy of Cancer (JITC)
    Vitenskapelig artikkel

2019

  • Rustad, Even Holth; Misund, Kristine; Bernard, Elsa; Coward, Eivind; Yellapantula, Venkata D; Hultcrantz, Malin. (2019) Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma. American Journal of Hematology
    Vitenskapelig artikkel
  • Misund, Kristine. (2019) Forekomst og betydning av MYC-translokasjoner i sykdomsforløpet ved myelomatose. Bestpractice Onkologi/Hematologi
    Fagartikkel
  • Misund, Kristine; Keane, Niamh; Stein, Caleb; Asmann, Yan; Day, Grady; Welsh, Seth. (2019) MYC dysregulation in the progression of multiple myeloma. Leukemia
    Vitenskapelig artikkel

2018

  • Olsen, Oddrun Elise; Sankar, Meenu; Elsaadi, Samah; Hella, Hanne; Buene, Glenn; Darvekar, Sagar. (2018) BMPR2 inhibits activin and BMP signaling via wild-type ALK2. Journal of Cell Science
    Vitenskapelig artikkel
  • Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind. (2018) Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. Blood
    Sammendrag/abstract
  • Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh. (2018) Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress. Nutrients
    Vitenskapelig artikkel
  • Holien, Toril; Misund, Kristine; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Buene, Glenn; Børset, Magne. (2018) Correction: MYC amplifications in myeloma cell lines: correlation with MYC-inhibitor efficacy. OncoTarget
    Errata

2017

  • Rustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese. (2017) Monitoring multiple myeloma by quantification of recurrent mutations in serum. Haematologica
    Vitenskapelig artikkel
  • Zahoor, Muhammad; Westhrin, Marita; Aass, Kristin Roseth; Moen, Siv Helen; Misund, Kristine; Psonka-Antonczyk, Katarzyna Maria. (2017) Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss. Blood Advances
    Vitenskapelig artikkel
  • Tangen, Jon-Magnus; Holien, Toril; Mirlashari, Mohammad Reza; Misund, Kristine; Hetland, Geir. (2017) Cytotoxic Effect on Human Myeloma Cells and Leukemic Cells by the Agaricus blazei Murill Based Mushroom Extract, Andosan™. BioMed Research International
    Vitenskapelig artikkel

2016

  • Baranowska, Katarzyna Anna; Misund, Kristine; Starheim, Kristian K.; Holien, Toril; Johansson, Ida; Darvekar, Sagar. (2016) Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells. OncoTarget
    Vitenskapelig artikkel
  • Misund, Kristine; Keane, Niamh; Asmann, Yan; Von Wier, Scott; Riggs, Daniel; Ahmann, Gregory. (2016) Complementary Activation of CCND, MYC, RAS and NFkB by Mutations in Multiple Myeloma. Blood
    Sammendrag/abstract
  • Abdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Holien, Toril; Sponaas, Anne-Marit. (2016) Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3. Molecular Cancer Research
    Vitenskapelig artikkel
  • Våtsveen, Thea Kristin; Sponaas, Anne Marit; Tian, Erming; Zhang, Qing; Misund, Kristine; Sundan, Anders. (2016) Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro. Journal of Hematology & Oncology
    Vitenskapelig artikkel
  • Starheim, Kristian Kobbenes; Holien, Toril; Misund, Kristine; Johansson, Ida; Baranowska, Katarzyna Anna; Sponaas, Anne Marit. (2016) Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells. Blood Cancer Journal
    Vitenskapelig artikkel
  • Slørdahl, Tobias Schmidt; Abdollahi, Pegah; Vandsemb, Esten Nymoen; Rampa, Christoph Samuel; Misund, Kristine; Baranowska, Katarzyna Anna. (2016) The phosphatase of regenerating liver-3 (PRL-3) is importantfor IL-6-mediated survival of myeloma cells. OncoTarget
    Vitenskapelig artikkel

2015

  • Follin-Arbelet, Virginie; Misund, Kristine; Naderi, Elin Hallan; Ugland, Hege Katrin; Sundan, Anders; Blomhoff, Heidi Kiil. (2015) The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM. Scientific Reports
    Vitenskapelig artikkel
  • Johansson, Ida; Monsen, Vivi Anita Talstad; Pettersen, Kristine; Mildenberger, Jennifer; Misund, Kristine; Kaarniranta, Kai. (2015) The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy
    Vitenskapelig artikkel
  • Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Starheim, Kristian K.; Johansson, Ida; Buene, Glenn. (2015) Chloroquine potentiates Carfilzomib but not Bortezomib effects on myeloma cells. Cancer Research
    Sammendrag/abstract
  • Wang, Huabo; Teriete, Peter; Hu, Angela; Raveendra-Panickar, Dhanya; Pendelton, Kelsey; Lazo, John S. (2015) Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids. OncoTarget
    Vitenskapelig artikkel
  • Rustad, Even Holth; Dai, Hong Yan; Coward, Eivind; Misund, Kristine; Sundan, Anders; Waage, Anders. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA. Blood
    Sammendrag/abstract
  • Rustad, Even Holth; Dai, Hong Yan; Hov, Håkon; Coward, Eivind; Beisvag, Vidar; Myklebost, Ola. (2015) BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. Blood Cancer Journal
    Vitenskapelig artikkel
  • Holien, Toril; Misund, Kristine; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Buene, Glenn; Børset, Magne. (2015) MYC amplifications in myeloma cell lines: Correlation with MYC-inhibitor efficacy. OncoTarget
    Vitenskapelig artikkel

2014

  • Holien, Toril; Misund, Kristine; Buene, Glenn; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Waage, Anders. (2014) MYC gene copy number determine MYC expression and sensitivity to a MYC-inhibitor in multiple myeloma cells. Cancer Research
    Sammendrag/abstract
  • Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Abdollahi, Pegah; Vansemb, Esten; Hagen, Lars; Baranowska, Katarzyna Anna. (2014) PRL-3 Mediates Survival of Primary Myeloma Cells. Blood
    Sammendrag/abstract
  • Selvik, Linn-Karina M.; Rao, Shalini; Steigedal, Tonje; Haltbakk, Ildri; Misund, Kristine; Bruland, Torunn. (2014) Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells. PLOS ONE
    Vitenskapelig artikkel
  • Olsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Mylin, Anne K.. (2014) Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. Blood Cancer Journal
    Vitenskapelig artikkel

2013

  • Müller, Rebekka; Misund, Kristine; Holien, Toril; Bachke, Siri; Gilljam, Karin Margaretha; Våtsveen, Thea Kristin. (2013) Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells. PLOS ONE
    Vitenskapelig artikkel
  • Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne. (2013) NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells. PLOS ONE
    Vitenskapelig artikkel
  • Holien, Toril; Olsen, Oddrun Elise; Misund, Kristine; Hella, Hanne; Waage, Anders; Rø, Torstein Baade. (2013) Lymphoma and myeloma cells are highly sensitive to growth arrest and apoptosis induced by artesunate. European Journal of Haematology
    Vitenskapelig artikkel
  • Selvik, Linn-Karina M.; Fjeldbo, Christina Sæten; Flatberg, Arnar; Steigedal, Tonje; Misund, Kristine; Anderssen, Endre. (2013) The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis. BMC Genomics
    Vitenskapelig artikkel
  • Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Rampa, Christoph Samuel; Klein, Dionne; Børset, Magne. (2013) A method for measurement of drug sensitivity of myeloma cells co-cultured with bone marrow stromal cells. Journal of Biomolecular Screening
    Vitenskapelig artikkel
  • Follin-Arbelet, Virginie; Torgersen, Maria Lyngaas; Naderi, Elin Hallan; Misund, Kristine; Sundan, Anders; Blomhoff, Heidi Kiil. (2013) Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway. Cancer Letters
    Vitenskapelig artikkel
  • Rø, Torstein Baade; Holien, Toril; Fagerli, Unn-Merete; Hov, Håkon; Misund, Kristine; Waage, Anders. (2013) HGF and IGF-1 synergize with SDF-1α in promoting migration of myeloma cells by cooperative activation of p21-activated kinase. Experimental Hematology
    Vitenskapelig artikkel

2012

  • Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Rampa, Christoph Samuel; Klein, Dionne; Børset, Magne. (2012) A Method for Measurement of Drug Sensitivity of Myeloma Cells Co-Cultured with Bone Marrow Stromal Cells. Blood
    Sammendrag/abstract
  • Slørdahl, Tobias Schmidt; Misund, Kristine; Rø, Torstein Baade; Børset, Magne. (2012) PRL-3 Regulates Myeloma Cell Survival, Proliferation, Adhesion and Migration. Blood
    Sammendrag/abstract

2010

  • Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv. (2010) Functional studies on RNA-transfected cell microarrays. Methods in molecular biology
    Vitenskapelig artikkel

2008

  • Fjeldbo, Christina Sæten; Misund, Kristine; Gunther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR)
    Vitenskapelig artikkel
  • Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje Strømmen; Thommesen, Liv. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR)
    Vitenskapelig artikkel

2007

  • Steigedal, Tonje Strømmen; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel
  • Misund, Kristine; Steigedal, Tonje Strømmen; Lægreid, Astrid; Thommesen, Liv. (2007) Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A. Journal of Cellular Biochemistry
    Vitenskapelig artikkel
  • Sætre, Rune; Ranang, Martin Thorsen; Steigedal, Tonje Strømmen; Stunes, Kamilla; Misund, Kristine; Thommesen, Liv. (2007) Webprot : online mining and annotation of biomedical literature using Google. Nova Science Publishers
    Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
  • Steigedal, Tonje; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel
  • Misund, Kristine; Steigedal, Tonje; Lægreid, Astrid; Thommesen, Liv. (2007) Inducible cAMP early repressor splice variants ICER I and II gamma both repress transcription of c-fos and chromogranin A. Journal of Cellular Biochemistry
    Vitenskapelig artikkel

2003

  • Misund, Kristine. (2003) Studier av transkripsjonsrepressoren ICER sin funksjon i regulering av CRE-styrt genuttrykk. [Mangler utgivernavn]
    Hovedfagsoppgave

Tidsskriftspublikasjoner

  • Mestvedt, Ingvild Bergdal; Menu, Eline; Misund, Kristine; Slørdahl, Tobias Schmidt; Rasheed, Kashif; Wolowczyk, Camilla Izabel. (2025) Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation. bioRxiv
    Vitenskapelig artikkel
  • Behsen, Alenka Djarmila; Vandsemb, Esten Nymoen; Slørdahl, Tobias Schmidt; Dybkær, Karen; Jakobsen, Maja Zimmer; Kashif, Muhammad. (2025) T cell phenotype and clonality changes in myeloma patients with short overall survival. JCI Insight
    Vitenskapelig artikkel
  • Berg, Sigrid Ravn; Demirovic, Aida; Sharma, Animesh; Hagen, Lars; Vågbø, Cathrine Broberg; Zatula, Alexey. (2024) Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens. Journal of Translational Medicine
    Vitenskapelig artikkel
  • Behsen, Alenka Djarmila; Holien, Toril; Micci, Francesca; Rye, Morten Beck; Rasmussen, Jenny Malm; Andersen, Kristin. (2024) Cell surface marker heterogeneity in human myeloma cell lines for modeling of disease and therapy. Scientific Reports
    Vitenskapelig artikkel
  • Jakobsen, Theresa; Pløen, Gro Grunnet; Behsen, Alenka Djarmila; Møller, Holger Jon; Plesner, Torben; Dybkær, Karen. (2024) The Prognostic Potential of circRNAs in Multiple Myeloma: Insights From Whole Bone Marrow and Purified Plasma Cells. Journal of Cellular and Molecular Medicine
    Vitenskapelig artikkel
  • Aass, Kristin Roseth; Tryggestad, Synne Stokke; Mjelle, Robin; Kastnes, Martin Haugrud; Nedal, Tonje Marie Vikene; Misund, Kristine. (2023) IL-32 is induced by activation of toll-like receptors in multiple myeloma cells. Frontiers in Immunology
    Vitenskapelig artikkel
  • Behsen, Alenka Djarmila; Vandsemb, Esten Nymoen; Slørdahl, Tobias Schmidt; Hjorth-Hansen, Henrik; Quist-Paulsen, Petter; Misund, Kristine. (2023) A patient with minimal myeloma treatment who survived for 20 years. Haematologica
    Vitenskapelig artikkel
  • Steiro, Ida Johnsen; Vandsemb, Esten Nymoen; Elsaadi, Samah; Misund, Kristine; Sponaas, Anne-Marit; Børset, Magne. (2022) The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells. OncoTarget
    Vitenskapelig artikkel
  • Giliberto, Mariaserena; Miranda Santana, Leonardo; Holien, Toril; Misund, Kristine; Nakken, Sigve; Vodak, Daniel. (2022) Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines. Frontiers in Oncology
    Vitenskapelig artikkel
  • Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco M.; Rustad, Even Holth; Sanders, Mathijs A.. (2022) Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence. Leukemia
    Vitenskapelig artikkel
  • Håland, Erling; Moen, Ingrid Nyhus; Veidal, Elias; Hella, Hanne; Misund, Kristine; Slørdahl, Tobias Schmidt. (2021) TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan. OncoTarget
    Vitenskapelig artikkel
  • Aass, Kristin Roseth; Mjelle, Robin; Kastnes, Martin Haugrud; Tryggestad, Synne Stokke; van den Brink, Luca Mare; Roseth, Ingrid Aass. (2021) Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells. iScience
    Vitenskapelig artikkel
  • Sponaas, Anne-Marit; Waage, Anders; Vandsemb, Esten; Misund, Kristine; Børset, Magne; Sundan, Anders. (2021) Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?. Frontiers in Immunology
    Vitenskapelig oversiktsartikkel/review
  • Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved. (2021) Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma. The FASEB Journal
    Vitenskapelig artikkel
  • Westhrin, Marita; Kovcic, Vlado; Zejian, Zhang; Moen, Siv Helen; Nedal, Tonje Marie Vikene; Bondt, Albert. (2020) Monoclonal immunoglobulins promote bone loss in multiple myeloma. Blood
    Vitenskapelig artikkel
  • Yang, Rui; Elsaadi, Samah; Misund, Kristine; Abdollahi, Pegah; Vandsemb, Esten; Moen, Siv Helen. (2020) Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade. Journal for ImmunoTherapy of Cancer (JITC)
    Vitenskapelig artikkel
  • Rustad, Even Holth; Misund, Kristine; Bernard, Elsa; Coward, Eivind; Yellapantula, Venkata D; Hultcrantz, Malin. (2019) Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma. American Journal of Hematology
    Vitenskapelig artikkel
  • Misund, Kristine. (2019) Forekomst og betydning av MYC-translokasjoner i sykdomsforløpet ved myelomatose. Bestpractice Onkologi/Hematologi
    Fagartikkel
  • Misund, Kristine; Keane, Niamh; Stein, Caleb; Asmann, Yan; Day, Grady; Welsh, Seth. (2019) MYC dysregulation in the progression of multiple myeloma. Leukemia
    Vitenskapelig artikkel
  • Olsen, Oddrun Elise; Sankar, Meenu; Elsaadi, Samah; Hella, Hanne; Buene, Glenn; Darvekar, Sagar. (2018) BMPR2 inhibits activin and BMP signaling via wild-type ALK2. Journal of Cell Science
    Vitenskapelig artikkel
  • Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind. (2018) Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. Blood
    Sammendrag/abstract
  • Petrovic, Voin; Nepal, Anala; Olaisen, Camilla; Bachke, Siri; Hira, Jonathan; Søgaard, Caroline Krogh. (2018) Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress. Nutrients
    Vitenskapelig artikkel
  • Holien, Toril; Misund, Kristine; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Buene, Glenn; Børset, Magne. (2018) Correction: MYC amplifications in myeloma cell lines: correlation with MYC-inhibitor efficacy. OncoTarget
    Errata
  • Rustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese. (2017) Monitoring multiple myeloma by quantification of recurrent mutations in serum. Haematologica
    Vitenskapelig artikkel
  • Zahoor, Muhammad; Westhrin, Marita; Aass, Kristin Roseth; Moen, Siv Helen; Misund, Kristine; Psonka-Antonczyk, Katarzyna Maria. (2017) Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss. Blood Advances
    Vitenskapelig artikkel
  • Tangen, Jon-Magnus; Holien, Toril; Mirlashari, Mohammad Reza; Misund, Kristine; Hetland, Geir. (2017) Cytotoxic Effect on Human Myeloma Cells and Leukemic Cells by the Agaricus blazei Murill Based Mushroom Extract, Andosan™. BioMed Research International
    Vitenskapelig artikkel
  • Baranowska, Katarzyna Anna; Misund, Kristine; Starheim, Kristian K.; Holien, Toril; Johansson, Ida; Darvekar, Sagar. (2016) Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells. OncoTarget
    Vitenskapelig artikkel
  • Misund, Kristine; Keane, Niamh; Asmann, Yan; Von Wier, Scott; Riggs, Daniel; Ahmann, Gregory. (2016) Complementary Activation of CCND, MYC, RAS and NFkB by Mutations in Multiple Myeloma. Blood
    Sammendrag/abstract
  • Abdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Holien, Toril; Sponaas, Anne-Marit. (2016) Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3. Molecular Cancer Research
    Vitenskapelig artikkel
  • Våtsveen, Thea Kristin; Sponaas, Anne Marit; Tian, Erming; Zhang, Qing; Misund, Kristine; Sundan, Anders. (2016) Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro. Journal of Hematology & Oncology
    Vitenskapelig artikkel
  • Starheim, Kristian Kobbenes; Holien, Toril; Misund, Kristine; Johansson, Ida; Baranowska, Katarzyna Anna; Sponaas, Anne Marit. (2016) Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells. Blood Cancer Journal
    Vitenskapelig artikkel
  • Slørdahl, Tobias Schmidt; Abdollahi, Pegah; Vandsemb, Esten Nymoen; Rampa, Christoph Samuel; Misund, Kristine; Baranowska, Katarzyna Anna. (2016) The phosphatase of regenerating liver-3 (PRL-3) is importantfor IL-6-mediated survival of myeloma cells. OncoTarget
    Vitenskapelig artikkel
  • Follin-Arbelet, Virginie; Misund, Kristine; Naderi, Elin Hallan; Ugland, Hege Katrin; Sundan, Anders; Blomhoff, Heidi Kiil. (2015) The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM. Scientific Reports
    Vitenskapelig artikkel
  • Johansson, Ida; Monsen, Vivi Anita Talstad; Pettersen, Kristine; Mildenberger, Jennifer; Misund, Kristine; Kaarniranta, Kai. (2015) The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy
    Vitenskapelig artikkel
  • Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Starheim, Kristian K.; Johansson, Ida; Buene, Glenn. (2015) Chloroquine potentiates Carfilzomib but not Bortezomib effects on myeloma cells. Cancer Research
    Sammendrag/abstract
  • Wang, Huabo; Teriete, Peter; Hu, Angela; Raveendra-Panickar, Dhanya; Pendelton, Kelsey; Lazo, John S. (2015) Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids. OncoTarget
    Vitenskapelig artikkel
  • Rustad, Even Holth; Dai, Hong Yan; Coward, Eivind; Misund, Kristine; Sundan, Anders; Waage, Anders. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA. Blood
    Sammendrag/abstract
  • Rustad, Even Holth; Dai, Hong Yan; Hov, Håkon; Coward, Eivind; Beisvag, Vidar; Myklebost, Ola. (2015) BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. Blood Cancer Journal
    Vitenskapelig artikkel
  • Holien, Toril; Misund, Kristine; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Buene, Glenn; Børset, Magne. (2015) MYC amplifications in myeloma cell lines: Correlation with MYC-inhibitor efficacy. OncoTarget
    Vitenskapelig artikkel
  • Holien, Toril; Misund, Kristine; Buene, Glenn; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Waage, Anders. (2014) MYC gene copy number determine MYC expression and sensitivity to a MYC-inhibitor in multiple myeloma cells. Cancer Research
    Sammendrag/abstract
  • Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Abdollahi, Pegah; Vansemb, Esten; Hagen, Lars; Baranowska, Katarzyna Anna. (2014) PRL-3 Mediates Survival of Primary Myeloma Cells. Blood
    Sammendrag/abstract
  • Selvik, Linn-Karina M.; Rao, Shalini; Steigedal, Tonje; Haltbakk, Ildri; Misund, Kristine; Bruland, Torunn. (2014) Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells. PLOS ONE
    Vitenskapelig artikkel
  • Olsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Mylin, Anne K.. (2014) Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. Blood Cancer Journal
    Vitenskapelig artikkel
  • Müller, Rebekka; Misund, Kristine; Holien, Toril; Bachke, Siri; Gilljam, Karin Margaretha; Våtsveen, Thea Kristin. (2013) Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells. PLOS ONE
    Vitenskapelig artikkel
  • Misund, Kristine; Selvik, Linn-Karina M.; Rao, Shalini; Nørsett, Kristin Gabestad; Bakke, Ingunn; Sandvik, Arne. (2013) NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells. PLOS ONE
    Vitenskapelig artikkel
  • Holien, Toril; Olsen, Oddrun Elise; Misund, Kristine; Hella, Hanne; Waage, Anders; Rø, Torstein Baade. (2013) Lymphoma and myeloma cells are highly sensitive to growth arrest and apoptosis induced by artesunate. European Journal of Haematology
    Vitenskapelig artikkel
  • Selvik, Linn-Karina M.; Fjeldbo, Christina Sæten; Flatberg, Arnar; Steigedal, Tonje; Misund, Kristine; Anderssen, Endre. (2013) The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis. BMC Genomics
    Vitenskapelig artikkel
  • Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Rampa, Christoph Samuel; Klein, Dionne; Børset, Magne. (2013) A method for measurement of drug sensitivity of myeloma cells co-cultured with bone marrow stromal cells. Journal of Biomolecular Screening
    Vitenskapelig artikkel
  • Follin-Arbelet, Virginie; Torgersen, Maria Lyngaas; Naderi, Elin Hallan; Misund, Kristine; Sundan, Anders; Blomhoff, Heidi Kiil. (2013) Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway. Cancer Letters
    Vitenskapelig artikkel
  • Rø, Torstein Baade; Holien, Toril; Fagerli, Unn-Merete; Hov, Håkon; Misund, Kristine; Waage, Anders. (2013) HGF and IGF-1 synergize with SDF-1α in promoting migration of myeloma cells by cooperative activation of p21-activated kinase. Experimental Hematology
    Vitenskapelig artikkel
  • Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Rampa, Christoph Samuel; Klein, Dionne; Børset, Magne. (2012) A Method for Measurement of Drug Sensitivity of Myeloma Cells Co-Cultured with Bone Marrow Stromal Cells. Blood
    Sammendrag/abstract
  • Slørdahl, Tobias Schmidt; Misund, Kristine; Rø, Torstein Baade; Børset, Magne. (2012) PRL-3 Regulates Myeloma Cell Survival, Proliferation, Adhesion and Migration. Blood
    Sammendrag/abstract
  • Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv. (2010) Functional studies on RNA-transfected cell microarrays. Methods in molecular biology
    Vitenskapelig artikkel
  • Fjeldbo, Christina Sæten; Misund, Kristine; Gunther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje; Thommesen, Liv. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR)
    Vitenskapelig artikkel
  • Fjeldbo, Christina Sæten; Misund, Kristine; Günther, Clara-Cecilie; Langaas, Mette; Steigedal, Tonje Strømmen; Thommesen, Liv. (2008) Functional studies on transfected cell microarray analysed by linear regression modelling. Nucleic Acids Research (NAR)
    Vitenskapelig artikkel
  • Steigedal, Tonje Strømmen; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel
  • Misund, Kristine; Steigedal, Tonje Strømmen; Lægreid, Astrid; Thommesen, Liv. (2007) Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A. Journal of Cellular Biochemistry
    Vitenskapelig artikkel
  • Steigedal, Tonje; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. American Journal of Physiology - Gastrointestinal and Liver Physiology
    Vitenskapelig artikkel
  • Misund, Kristine; Steigedal, Tonje; Lægreid, Astrid; Thommesen, Liv. (2007) Inducible cAMP early repressor splice variants ICER I and II gamma both repress transcription of c-fos and chromogranin A. Journal of Cellular Biochemistry
    Vitenskapelig artikkel

Del av bok/rapport

  • Sætre, Rune; Ranang, Martin Thorsen; Steigedal, Tonje Strømmen; Stunes, Kamilla; Misund, Kristine; Thommesen, Liv. (2007) Webprot : online mining and annotation of biomedical literature using Google. Nova Science Publishers
    Vitenskapelig Kapittel/Artikkel/Konferanseartikkel

Rapport

  • Misund, Kristine. (2003) Studier av transkripsjonsrepressoren ICER sin funksjon i regulering av CRE-styrt genuttrykk. [Mangler utgivernavn]
    Hovedfagsoppgave

Undervisning

Emner

  • MOL3001 - Medical Genetics

Formidling

2024

  • Poster
    Andersson-Rusch, Clara; Quist-Løkken, Ingrid; Sætrom, Pål; Hanif, Md Abu; Rolinski, Milosz; Møen, Johanna. (2024) Whole genome CRISPR knockout screen reveals key function for ID3 in regulating myeloma cell survival via TCF3 and c-MYC. FASEB TGF-β Superfamily , Niagara Falls, NY 2024-07-21 - 2024-07-25
  • Poster
    Mestvedt, Ingvild Bergdal; Yurchenko, Maria; Espevik, Terje; Standal, Therese; Wolowczyk, Camilla Izabel; Rasheed, Kashif. (2024) Exploring peptide derived from Signaling Lymphocytic Activation Molecule Family 1 as novel treatment for multiple myeloma. EORTC NCI and AACR (ENA) ENA 2024 Symposium on molecular targets and cancer therapeutics , Barcelona 2024-10-23 - 2024-10-25

2023

  • Poster
    Andersson-Rusch, Clara Leticia; Quist-Løkken, Ingrid; Sætrom, Pål; Beisvag, Vidar; Rolinski, Milosz; Møen, Johanna. (2023) Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma. American Society of Hematology 65th ASH Annual Meeting and Exposition 2023-12-09 - 2023-12-12

2022

  • Vitenskapelig foredrag
    Behsen, Alenka Djarmila; Vandsemb, Esten Nymoen; Waage, Anders; Slørdahl, Tobias Schmidt; Sponaas, Anne Marit; Misund, Kristine. (2022) Altered composition of CD8 T cell subsets over time in the bone marrow of multiple myeloma patients with long- and short-term disease control. International Myeloma Society (IMS) International Myeloma Society Annual Meeting , Los Angeles, CA, USA 2022-08-25 - 2022-08-27

2021

  • Vitenskapelig foredrag
    Behsen, Alenka Djarmila; Vandsemb, Esten Nymoen; Waage, Anders; Slørdahl, Tobias Schmidt; Sponaas, Anne-Marit; Misund, Kristine. (2021) Altered composition of CD8 T cells subsets over time in the bone marrow of multiple myeloma patients with long-term disease control and short-term disease control. Nordic Myeloma Study Group NMSG Meeting , Stockholm 2021-09-16 - 2021-09-17

2018

  • Poster
    Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind. (2018) Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. American Society of Hematology (ASH) 2018 2018-12-01 - 2018-12-04
  • Vitenskapelig foredrag
    Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind. (2018) Clonal Evolution of Multiple Myeloma After Treatment with Novel Agents . 2nd. International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer 2018-06-14 - 2018-06-15
  • Vitenskapelig foredrag
    Misund, Kristine. (2018) Next-generation sequencing - Status og Nyheter. Nyheter inom myelom med ett multidisciplinärt fokus – Ny diagnostik, next generation sequenzing, högrisk myelom, uppdaterat vårdprogram, motivering av patienten etc. 2018-09-18 -
  • Poster
    Olsen, Oddrun Elise; Sankar, Meenu; Elsaadi, Samah; Hella, Hanne; Darvekar, Sagar; Misund, Kristine. (2018) BMPR2 inhibits activin- and BMP-signaling via wild type ALK2. NTNU 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer: From diagnosis to immunotherapy – why is precision medicine so difficult? , Trondheim 2018-06-14 - 2018-06-15
  • Poster
    Yang, Rui; Elsaadi, Samah; Misund, Kristine; Slupphaug, Geir; Menu, Eline; Hay, Carl. (2018) Role of ectoenzymes CD39 and CD73 in the immune response to multiple myeloma . American Association for Cancer Research Annual Meeting of the American Association for Cancer Research , Chicago 2018-04-14 - 2018-04-18

2017

  • Vitenskapelig foredrag
    Keane, Niamh; Stein, Caleb; Angelov, Daniel; Tian, Shulan; Wiswanatha, David; Kumar, Shaji K.. (2017) MYC Translocations Identified By Sequencing Panel in Smoldering Multiple Myeloma Strongly Predict for Rapid Progression to Multiple Myeloma . American Society of Hematology American Society of Hematology 2017 , Atlanta 2017-12-09 - 2017-12-12
  • Vitenskapelig foredrag
    Misund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind. (2017) Detection of mutations in Multiple Myeloma during different stages of disease. NMSG NMSG plenary meeting , Trondheim 2017-09-07 - 2017-09-08
  • Poster
    Coward, Eivind; Misund, Kristine; Hofste op Bruinink, Davine; Hoogenboezem, Remco; Rustad, Even Holth; Myklebost, Ola. (2017) Exome sequencing of multiple myeloma at sequential time points. Barbara van Loon, IKM, NTNU Trondheim - Oslo Genome Dynamics Workshop , Trondheim 2017-06-15 - 2017-06-16
  • Vitenskapelig foredrag
    Olsen, Oddrun Elise; Sankar, Meenu; Darvekar, Sagar; Misund, Kristine; Sundan, Anders; Holien, Toril. (2017) Activins induce apoptosis through wild type ALK2/ACVR1 and are counteracted by BMPR2. FASEB The TGFb Superfamily: Signaling in Development and Disease , Lisboa 2017-07-09 - 2017-07-14
  • Vitenskapelig foredrag
    Olsen, Oddrun Elise; Sankar, Meenu; Elsaadi, Samah; Hella, Hanne; Darvekar, Sagar; Misund, Kristine. (2017) Activins induce apoptosis through wild type ALK2/ACVR1 and are counteracted by BMPR2. Nordic Myeloma Study Group NMSG plenary meeting , Trondheim 2017-09-07 - 2017-09-08

2016

  • Poster
    Rustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese. (2016) Circulating Tumor DNA in Multiple Myeloma . European Hematology Association European Hematology Association 21th Congress , Copenhagen 2016-06-09 - 2016-06-12
  • Vitenskapelig foredrag
    Misund, Kristine; Keane, Niamh; Asmann, Yan; Van Wier, Scott; Riggs, Daniel; Ahmann, Gregory. (2016) Complementary Activation of CCND, MYC, RAS and NFkB by Mutations in Multiple Myeloma. The American Society of Hematology 58th ASH Annual Meeting and Exposition , San Diego 2016-12-02 - 2016-12-06

2015

  • Poster
    Abdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Rø, Torstein Baade; Slørdahl, Tobias Schmidt. (2015) PRL-3 increases survival of Multiple Myeloma cells through Src activation. 15th International Myeloma Workshop , Roma 2015-09-23 - 2015-09-25
  • Poster
    Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Starheim, Kristian K.; Johansson, Ida; Buene, Glenn. (2015) Chloroquine potentiates Carfilzomib but not Bortezomib effects on myeloma cells. AACR 106th Annual Meeting 2015 , Philadelphia, PA 2015-04-18 - 2015-04-22
  • Vitenskapelig foredrag
    Rustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Dai, Hong Yan. (2015) Exome sequencing of tumor samples as starting point for monitoring mutations in circulating DNA of patients with multiple myeloma. NCGC Norwegian Cancer Genomics Consortium (NCGC) Symposium , Oslo 2015-10-27 - 2015-10-28
  • Poster
    Rustad, Even Holth; Dai, Hong Yan; Coward, Eivind; Misund, Kristine; Sundan, Anders; Waage, Anders. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA. The American Society of Hematology 57th ASH Annual Meeting and Exposition , Orlando 2015-12-05 - 2015-12-08
  • Vitenskapelig foredrag
    Coward, Eivind; Misund, Kristine; Rustad, Even Holth; Sundan, Anders; Waage, Anders. (2015) Mutations in multiple myeloma at sequential time points. Norsk kreftgenomikkonsortium NCGC Symposium 2015 , Losby Gods 2015-10-27 - 2015-10-28
  • Vitenskapelig foredrag
    Rustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Dai, Hong Yan. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients by Digital PCR of Circulating DNA. NMSG Nordic Myeloma Study Group (NMSG) Annual Meeting , Stockholm 2015-11-12 - 2015-11-13
  • Populærvitenskapelig foredrag
    Misund, Kristine; Grøseth, Lill Anny Gunnes; Holien, Toril. (2015) Forskning på myelomatose. Klassebesøk, 3. trinn v.g.s. med fordypning i biologi 2015-03-18 - 2015-03-18

2014

  • Poster
    Rø, Torstein Baade; Slørdahl, Tobias Schmidt; Abdollahi, Pegah; Vansemb, Esten; Hagen, Lars; Baranowska, Katarzyna Anna. (2014) PRL-3 Mediates Survival of Primary Myeloma Cells. American Society of Hematology American Society of Hematology Annual Meeting , San Francisco 2014-12-06 - 2014-12-09
  • Faglig foredrag
    Misund, Kristine; Coward, Eivind; Waage, Anders. (2014) Norwegian Cancer Genomics Consortium - Multiple Myeloma projects. Norsk selskap for Hematolgi Høstmøte for Norsk selskap for Hematologi , Oslo 2014-11-04 - 2014-11-05
  • Populærvitenskapelig foredrag
    Holien, Toril; Grøseth, Lill Anny Gunnes; Standal, Therese; Misund, Kristine; Bruvoll, Ingrid; Nordrum, Ivar Skjåk. (2014) Hvordan jobber en kreftforsker + Besøk i medisinsk museum i Kunnskapssenteret. Klassebesøk, 5. trinn barneskole 2014-03-19 - 2014-03-19
  • Poster
    Holien, Toril; Misund, Kristine; Buene, Glenn; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Waage, Anders. (2014) MYC gene copy number determine MYC expression and sensitivity to a MYC-inhibitor in multiple myeloma cells. American Association for Cancer Research AACR Annual Meeting 2014 , San Diego, CA 2014-04-05 - 2014-04-09
  • Intervju
    Misund, Kristine. (2014) Millionstøtte . Romsdals budstikke Romsdals budstikke [Avis] 2014-10-31
  • Intervju
    Misund, Kristine. (2014) Får penger til tre års forskning. adressa nett og papir adressa nett og papir [Avis] 2014-10-29

2013

  • Poster
    Rao, Shalini; Thommesen, Liv; Nørsett, Kristin; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn. (2013) Nr4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. NBS Sør-Trøndelag Kontaktmøte Norsk Biokjemisk Selskap , Røros 2013-01-17 - 2013-01-20
  • Poster
    Olsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Størdal, Berit Fladvad. (2013) Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. FASEB TGF-B Superfamily: Signaling in Development and Disease 2013-07-28 - 2013-08-02
  • Poster
    Rao, Shalini; Selvik, Linn-Karina M.; Nørsett, Kristin Gabestad; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn. (2013) NR4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. EMBO Conference Nuclear receptors: Linking molecules, genomes & physiology , Sorrento 2013-09-06 - 2013-09-10
  • Poster
    Slørdahl, Tobias Schmidt; Misund, Kristine; Rø, Torstein Baade; Børset, Magne. (2013) The Phosphatase of Regenerating Liver-3 (PRL-3) Is Essential for IL-6-mediated Survival of Myeloma Cells. 14th International Myeloma Workshop , Kyoto 2013-04-03 - 2013-04-07
  • Populærvitenskapelig foredrag
    Holien, Toril; Sponaas, Anne-Marit; Misund, Kristine; Rø, Torstein Baade; Brede, Gaute; Standal, Therese. (2013) "Ta livet av kreftcellene" Stand i samarbeid med Kreftforeningen. NTNU - Forskningsdagene Forskningstorget , Trondheim 2013-09-20 - 2013-09-21
  • Faglig foredrag
    Olsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Størdal, Berit Fladvad. (2013) Membrane bound and soluble endoglin protects myeloma cells from bone morphogenetic protein 9 induced apoptosis. NBS vintermøte 2013-01-17 - 2013-01-20

2012

  • Poster
    Slørdahl, Tobias Schmidt; Misund, Kristine; Rø, Torstein Baade; Børset, Magne. (2012) PRL-3 Regulates Myeloma Cell Survival, Proliferation, Adhesion and Migration. American Society of Hematology The 54th Annual Meeting of the American Society of Hematology (ASH) , Atlanta 2012-12-07 - 2012-12-11
  • Poster
    Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Rampa, Christoph Samuel; Klein, Dionne; Børset, Magne. (2012) A Method for Measurement of Drug Sensitivity of Myeloma Cells Co-Cultured with Bone Marrow Stromal Cells. American Society of Hematology The American Society of Hematology (ASH) annual meeting , Atlanta, Georgia 2012-12-07 - 2012-12-11
  • Poster
    Misund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Rampa, Christoph Samuel; Waage, Anders; Sundan, Anders. (2012) Attempts to predict response to cytostatics in Multiple Myeloma patients. Norwegian Biochemical Society Norwegian Biochemical Society Contact Meeting , Storefjell 2012-01-19 - 2012-01-22

2010

  • Poster
    Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Fjeldbo, Christina Sæten; Flatberg, Arnar; Selvik, Linn-Karina M.. (2010) Exploring signal-induced cellular regulatory subnetworks by use of partial least square regression (PLSR) multidimensional analysis of gene expression time series data. The MGED Society 13th Annual MGED meeting , Boston, Massachusetts, USA , Boston 2010-07-13 - 2010-07-15

2009

  • Vitenskapelig foredrag
    Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten. (2009) Basic common architectural motifs underlying gastrin induced gene expression can be identified by dimention reduction methods. NBS Trondheim NBS 43. Contact Meeting , Røros 2009-01-17 - 2009-01-20
  • Poster
    Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Beisvag, Vidar; Sandvik, Arne Kristian; Thommesen, Liv. (2009) Discovering basic network motifs that underlie gastrin induced gene expression. ICSB The 10th International Conference on System Biology ICSB-2009, USA , Standford, Calefornia 2009-08-30 - 2009-09-04
  • Vitenskapelig foredrag
    Selvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje; Bruland, Torunn; Lægreid, Astrid. (2009) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response and is repressed by ICER and Zfp36l1. NBS NBS Kontaktmøte 2009 , Røros 2009-01-29 - 2009-02-01
  • Poster
    Anderssen, Endre; Bruland, Torunn; Misund, Kristine; Sandvik, Arne K.; Thommesen, Liv; Lægreid, Astrid. (2009) Using basic networks motifs and biological background knowledge to analyze transcriptomic time series data. MGED Meeting , Phoenix, USA 2009-10-05 - 2009-10-08
  • Poster
    Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Beisvåg, Vidar; Sandvik, Arne K.; Lægreid, Astrid. (2009) Discovering basic network motifs that underlie gastrin induced gene expression. 10th international conference on system biology , San Francisco 2009-08-30 - 2009-09-04
  • Vitenskapelig foredrag
    Thommesen, Liv; Misund, Kristine; Selvik, Linn Karina Myrland; Lægreid, Astrid; Bruland, Torunn. (2009) NR4A" (Nurr1) - involved in gastrin-mediated carcinogenesis?. Contact meeting NBS , Røros 2009-01-22 - 2009-01-25
  • Vitenskapelig foredrag
    Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Doseth, Berit; Langaas, Mette. (2009) Basic common architectural motifs underlying gastrin induced gene expression can be identified by dimension reduction methods. Contact Meeting NBS , Røros 2009-01-22 - 2009-01-25

2008

  • Poster
    Bruland, Torunn; Andersen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Fjeldbo, Christina Sæten; Lægreid, Astrid. (2008) Molecular mecanisms in cancer-related gastrin responses. Cancer Epigenetics , Boston 2008-05-28 - 2008-05-31
  • Poster
    Selvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje Strømmen; Bruland, Torunn; Lægreid, Astrid. (2008) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response. ESF Functional Genomics and Disease , Innsbruck 2008-10-01 - 2008-10-05
  • Poster
    Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Doseth, Berit; Fjeldbo, Christina Sæten. (2008) Significance analysis of gastrin-mediated transcription using dimension reduction methods for interpreting and modelling DNA microarray time series gene expression data. ESF Functional Genomics and Disease , Innsbruck 2008-10-01 - 2008-10-05
  • Poster
    Misund, Kristine; Selvik, Linn-Karina M.; Slettahjell Prestvik, Wenche; Thommesen, Liv. (2008) miRNA and mRNA expression in HEK cells with inducible expression of tumour repressor ICER. ESF Functional genomics and Diseases , Innsbruck, Austria 2008-10-01 - 2008-10-05
  • Poster
    Misund, Kristine; Johansen, Alice; Selvik, Linn-Karina M.; Prestvik, Wenche Slettahjell; Thommesen, Liv. (2008) miRNA and mRNA expression in HEK cells with inducible expression of tumour suppressor ICER. Functional Genomics and Disease , Innsbruck, Austria 2008-10-01 - 2008-10-04
  • Poster
    Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten. (2008) Significance analysis of gastrin-mediated transcription using dimension reduction methods for interpreting and modelling DNA microarray time series gene expression. 3rd ESF Functional Genomics Conference; Functional genomics and disease , Insnsbruck 2008-10-01 - 2008-10-04
  • Poster
    Bruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten. (2008) Molecular mechanisms in cancer related gastrin responses. American Association for Cancer Research Cancer Epigenetics Conference , Boston 2008-05-28 - 2008-05-31
  • Poster
    Selvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje; Bruland, Torunn; Lægreid, Astrid. (2008) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response. ESF Functional Genomics and Disease Conference , Innsbruck 2008-10-01 - 2008-10-04

2007

  • Vitenskapelig foredrag
    Sæten, Christina; Misund, Kristine; Steigedal, Tonje; Otterlei, Marit; Lægreid, Astrid; Thommesen, Liv. (2007) Complex functional studies in mammalian cells using transfected cell arrays. Norsk Biokjemisk Selskap (NBS) The Norwegian Bichemical Society 43. Contact Meeting , Lillehammer 2007-02-01 - 2007-02-04
  • Vitenskapelig foredrag
    Steigedal, Tonje; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor (ICER) suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. Norsk Biokjemisk Selskap The Norwegian Bichemical Society 43. Contact Meeting , Lillehammer 2007-02-01 - 2007-02-04
  • Poster
    Sæten, Christina; Misund, Kristine; Steigedal, Tonje Strømmen; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2007) Complex functional studies in mammalian cells using transfected cell arrays. Norsk Biokjemisk Selskaps 43. kontaktmøte , Lillehammer 2007-02-01 - 2007-02-04
  • Poster
    Steigedal, Tonje Strømmen; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor (ICER) suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. Norsk Biokjemisk Selskaps 43. kontaktmøte , Lillehammer 2007-02-01 - 2007-02-04
  • Poster
    Misund, Kristine; Hoel, Sunniva; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2007) Global gene expression in HEK 293 cells with controllable ICER I and IIg - overexpression. Norsk Biokjemisk Selskaps 43. kontaktmøte , Lillehammer 2007-02-01 - 2007-02-04
  • Poster
    Misund, Kristine; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2007) Global gene expression in HEK 293 cells with controllable ICER I and II gamma overexpression. NBS kontaktmøte 2007 , Lillehammer 2007-02-01 - 2007-02-01

2006

  • Poster
    Misund, Kristine; Hoel, Sunniva; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2006) Global gene expression in HEK 293 cells with controllable ICER I or IIgamma overexpression. The Seventh International Conference on Systems Biology; ICSB 2006 2006-10-08 - 2006-10-13

2005

  • Poster
    Misund, Kristine; Lægreid, Astrid; Thommesen, Liv. (2005) Constitutive and inducible expression of ICER in HEK 293. NBS kontaktmøte , Tromsø 2005-01-13 - 2005-01-16
  • Poster
    Steigedal, Tonje Strømmen; Bruland, Torunn; Ween, Ola; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2005) Function of splice variants of the transcriptional repressor ICER in gastrin-mediated reponses. NBS kontaktmøte , Tromsø 2005-01-13 - 2005-01-16
  • Vitenskapelig foredrag
    Nørsett, K; Bruland, Torunn; Ween, Ola; Hofsli, Eva; Thommesen, Liv; Misund, Kristine. (2005) Systems biology of the normal and diseased gastrointestinal system. 2nd ESF Function genomics and disease , Oslo 2005-09-06 - 2005-09-10
  • Vitenskapelig foredrag
    Nørsett, Kristin; Bruland, Torunn; Ween, Ola; Hofsli, Eva; Thommesen, Liv; Misund, Kristine. (2005) Systems biology of the normal and diseased gastrointestinal system. 2nd ESF Functional Genomics Conference 2005-01-10 - 2005-01-13
  • Vitenskapelig foredrag
    Misund, Kristine; Lægreid, Astrid; Thommesen, Liv. (2005) Constitutive and inducible expression of ICER in HEK 293. Kontaktmøtet Norsk Biokjemisk Selskap 2005 2005-01-13 - 2005-01-16
  • Poster
    Steigedal, Tonje S.; Bruland, Torunn; Ween, Ola; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2005) Function of splice variants of the transcriptional repressor ICER in gastrin-mediated responses. The Norwegian Biochemical Society 41st Contact Meeting 2005-01-13 - 2005-01-16

2004

  • Poster
    Misund, Kristine; Stunes, Astrid Kamilla; Tømmerdal, Linda; Thommesen, Liv; Bruland, Torunn; Lægreid, Astrid. (2004) Constitutive expression of ICER in the cell-line HEK 293. Kontaktmøtet Norsk Biokjemisk Selskap 2004 2004-01-15 - 2004-01-18

2003

  • Poster
    Thommesen, Liv; Lægreid, Astrid; Misund, Kristine. (2003) Constitutive expression of ICER in the human cell line AR42J. Kontaktmøtet Norsk Biokjemisk Selskap , Geilo 2003-01-23 - 2003-01-26
  • Poster
    Thommesen, Liv; Lægreid, Astrid; Misund, Kristine. (2003) Constitutive expression of ICER in the human cell line AR42J. Kontaktmøtet Norsk Biokjemisk Selskap , Geilo 2003-01-26 -

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