Kristine Misund
Om
Jobber som forsker ved Senter for Myelomforskning ved Institutt for klinisk og molekylær medisin.
Vi forsker på Myelomatose, som er en kreftform som oppstår i de antistoff produserende plasmacellene i beinmargen. Dette er en type blodkreft som rammer ca. 400 personer i Norge hvert år. Hovedfokuset i min forskning, er på det å undersøke og forstå de genetiske og molekylære endringene som skjer med kreftcellene fra diagnose tidspunktet og til utviklingen av en tumor som er resistent mot medikamenter. Vi prøver også å forstå hvorfor noen lever lenge med sykdommen mens andre har en aggressiv sykdom, og prøver å finne nye biomarkører for dette, ved å undersøke både kreftceller og de omkringliggende cellene. Vi bruker NGS sekvensering, CyTOF analyser, i tillegg til veletablerte cellebiologiske metoder.
Publikasjoner
2025
-
Mestvedt, Ingvild Bergdal;
Menu, Eline;
Misund, Kristine;
Slørdahl, Tobias Schmidt;
Rasheed, Kashif;
Wolowczyk, Camilla Izabel.
(2025)
Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation.
bioRxiv
Vitenskapelig artikkel
-
Behsen, Alenka Djarmila;
Vandsemb, Esten Nymoen;
Slørdahl, Tobias Schmidt;
Dybkær, Karen;
Jakobsen, Maja Zimmer;
Kashif, Muhammad.
(2025)
T cell phenotype and clonality changes in myeloma patients with short overall survival.
JCI Insight
Vitenskapelig artikkel
2024
-
Berg, Sigrid Ravn;
Demirovic, Aida;
Sharma, Animesh;
Hagen, Lars;
Vågbø, Cathrine Broberg;
Zatula, Alexey.
(2024)
Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens.
Journal of Translational Medicine
Vitenskapelig artikkel
-
Behsen, Alenka Djarmila;
Holien, Toril;
Micci, Francesca;
Rye, Morten Beck;
Rasmussen, Jenny Malm;
Andersen, Kristin.
(2024)
Cell surface marker heterogeneity in human myeloma cell lines for modeling of disease and therapy.
Scientific Reports
Vitenskapelig artikkel
-
Jakobsen, Theresa;
Pløen, Gro Grunnet;
Behsen, Alenka Djarmila;
Møller, Holger Jon;
Plesner, Torben;
Dybkær, Karen.
(2024)
The Prognostic Potential of circRNAs in Multiple Myeloma: Insights From Whole Bone Marrow and Purified Plasma Cells.
Journal of Cellular and Molecular Medicine
Vitenskapelig artikkel
2023
-
Aass, Kristin Roseth;
Tryggestad, Synne Stokke;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Nedal, Tonje Marie Vikene;
Misund, Kristine.
(2023)
IL-32 is induced by activation of toll-like receptors in multiple myeloma cells.
Frontiers in Immunology
Vitenskapelig artikkel
-
Behsen, Alenka Djarmila;
Vandsemb, Esten Nymoen;
Slørdahl, Tobias Schmidt;
Hjorth-Hansen, Henrik;
Quist-Paulsen, Petter;
Misund, Kristine.
(2023)
A patient with minimal myeloma treatment who survived for 20 years.
Haematologica
Vitenskapelig artikkel
2022
-
Steiro, Ida Johnsen;
Vandsemb, Esten Nymoen;
Elsaadi, Samah;
Misund, Kristine;
Sponaas, Anne-Marit;
Børset, Magne.
(2022)
The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells.
OncoTarget
Vitenskapelig artikkel
-
Giliberto, Mariaserena;
Miranda Santana, Leonardo;
Holien, Toril;
Misund, Kristine;
Nakken, Sigve;
Vodak, Daniel.
(2022)
Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines.
Frontiers in Oncology
Vitenskapelig artikkel
-
Misund, Kristine;
Hofste op Bruinink, Davine;
Coward, Eivind;
Hoogenboezem, Remco M.;
Rustad, Even Holth;
Sanders, Mathijs A..
(2022)
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence.
Leukemia
Vitenskapelig artikkel
2021
-
Håland, Erling;
Moen, Ingrid Nyhus;
Veidal, Elias;
Hella, Hanne;
Misund, Kristine;
Slørdahl, Tobias Schmidt.
(2021)
TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan.
OncoTarget
Vitenskapelig artikkel
-
Aass, Kristin Roseth;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Tryggestad, Synne Stokke;
van den Brink, Luca Mare;
Roseth, Ingrid Aass.
(2021)
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells.
iScience
Vitenskapelig artikkel
-
Sponaas, Anne-Marit;
Waage, Anders;
Vandsemb, Esten;
Misund, Kristine;
Børset, Magne;
Sundan, Anders.
(2021)
Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?.
Frontiers in Immunology
Vitenskapelig oversiktsartikkel/review
-
Abdollahi, Pegah;
Vandsemb, Esten;
Elsaadi, Samah;
Røst, Lisa Marie;
Yang, Rui;
Hjort, Magnus Aassved.
(2021)
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma.
The FASEB Journal
Vitenskapelig artikkel
2020
-
Westhrin, Marita;
Kovcic, Vlado;
Zejian, Zhang;
Moen, Siv Helen;
Nedal, Tonje Marie Vikene;
Bondt, Albert.
(2020)
Monoclonal immunoglobulins promote bone loss in multiple myeloma.
Blood
Vitenskapelig artikkel
-
Yang, Rui;
Elsaadi, Samah;
Misund, Kristine;
Abdollahi, Pegah;
Vandsemb, Esten;
Moen, Siv Helen.
(2020)
Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade.
Journal for ImmunoTherapy of Cancer (JITC)
Vitenskapelig artikkel
2019
-
Rustad, Even Holth;
Misund, Kristine;
Bernard, Elsa;
Coward, Eivind;
Yellapantula, Venkata D;
Hultcrantz, Malin.
(2019)
Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma.
American Journal of Hematology
Vitenskapelig artikkel
-
Misund, Kristine.
(2019)
Forekomst og betydning av MYC-translokasjoner i sykdomsforløpet ved myelomatose.
Bestpractice Onkologi/Hematologi
Fagartikkel
-
Misund, Kristine;
Keane, Niamh;
Stein, Caleb;
Asmann, Yan;
Day, Grady;
Welsh, Seth.
(2019)
MYC dysregulation in the progression of multiple myeloma.
Leukemia
Vitenskapelig artikkel
2018
-
Olsen, Oddrun Elise;
Sankar, Meenu;
Elsaadi, Samah;
Hella, Hanne;
Buene, Glenn;
Darvekar, Sagar.
(2018)
BMPR2 inhibits activin and BMP signaling via wild-type ALK2.
Journal of Cell Science
Vitenskapelig artikkel
-
Misund, Kristine;
Hofste op Bruinink, Davine;
Coward, Eivind;
Hoogenboezem, Remco;
Rustad, Even Holth;
Hovig, Eivind.
(2018)
Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse.
Blood
Sammendrag/abstract
-
Petrovic, Voin;
Nepal, Anala;
Olaisen, Camilla;
Bachke, Siri;
Hira, Jonathan;
Søgaard, Caroline Krogh.
(2018)
Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress.
Nutrients
Vitenskapelig artikkel
-
Holien, Toril;
Misund, Kristine;
Olsen, Oddrun Elise;
Baranowska, Katarzyna Anna;
Buene, Glenn;
Børset, Magne.
(2018)
Correction: MYC amplifications in myeloma cell lines: correlation
with MYC-inhibitor efficacy.
OncoTarget
Errata
2017
-
Rustad, Even Holth;
Coward, Eivind;
Skytøen, Emilie R;
Misund, Kristine;
Holien, Toril;
Standal, Therese.
(2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum.
Haematologica
Vitenskapelig artikkel
-
Zahoor, Muhammad;
Westhrin, Marita;
Aass, Kristin Roseth;
Moen, Siv Helen;
Misund, Kristine;
Psonka-Antonczyk, Katarzyna Maria.
(2017)
Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss.
Blood Advances
Vitenskapelig artikkel
-
Tangen, Jon-Magnus;
Holien, Toril;
Mirlashari, Mohammad Reza;
Misund, Kristine;
Hetland, Geir.
(2017)
Cytotoxic Effect on Human Myeloma Cells and Leukemic Cells by the Agaricus blazei Murill Based Mushroom Extract, Andosan™.
BioMed Research International
Vitenskapelig artikkel
2016
-
Baranowska, Katarzyna Anna;
Misund, Kristine;
Starheim, Kristian K.;
Holien, Toril;
Johansson, Ida;
Darvekar, Sagar.
(2016)
Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells.
OncoTarget
Vitenskapelig artikkel
-
Misund, Kristine;
Keane, Niamh;
Asmann, Yan;
Von Wier, Scott;
Riggs, Daniel;
Ahmann, Gregory.
(2016)
Complementary Activation of CCND, MYC, RAS and NFkB by Mutations in Multiple Myeloma.
Blood
Sammendrag/abstract
-
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Hjort, Magnus Aassved;
Misund, Kristine;
Holien, Toril;
Sponaas, Anne-Marit.
(2016)
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3.
Molecular Cancer Research
Vitenskapelig artikkel
-
Våtsveen, Thea Kristin;
Sponaas, Anne Marit;
Tian, Erming;
Zhang, Qing;
Misund, Kristine;
Sundan, Anders.
(2016)
Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro.
Journal of Hematology & Oncology
Vitenskapelig artikkel
-
Starheim, Kristian Kobbenes;
Holien, Toril;
Misund, Kristine;
Johansson, Ida;
Baranowska, Katarzyna Anna;
Sponaas, Anne Marit.
(2016)
Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells.
Blood Cancer Journal
Vitenskapelig artikkel
-
Slørdahl, Tobias Schmidt;
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Rampa, Christoph Samuel;
Misund, Kristine;
Baranowska, Katarzyna Anna.
(2016)
The phosphatase of regenerating liver-3 (PRL-3) is importantfor IL-6-mediated survival of myeloma cells.
OncoTarget
Vitenskapelig artikkel
2015
-
Follin-Arbelet, Virginie;
Misund, Kristine;
Naderi, Elin Hallan;
Ugland, Hege Katrin;
Sundan, Anders;
Blomhoff, Heidi Kiil.
(2015)
The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM.
Scientific Reports
Vitenskapelig artikkel
-
Johansson, Ida;
Monsen, Vivi Anita Talstad;
Pettersen, Kristine;
Mildenberger, Jennifer;
Misund, Kristine;
Kaarniranta, Kai.
(2015)
The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells.
Autophagy
Vitenskapelig artikkel
-
Misund, Kristine;
Baranowska, Katarzyna Anna;
Holien, Toril;
Starheim, Kristian K.;
Johansson, Ida;
Buene, Glenn.
(2015)
Chloroquine potentiates Carfilzomib but not Bortezomib effects on myeloma cells.
Cancer Research
Sammendrag/abstract
-
Wang, Huabo;
Teriete, Peter;
Hu, Angela;
Raveendra-Panickar, Dhanya;
Pendelton, Kelsey;
Lazo, John S.
(2015)
Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids.
OncoTarget
Vitenskapelig artikkel
-
Rustad, Even Holth;
Dai, Hong Yan;
Coward, Eivind;
Misund, Kristine;
Sundan, Anders;
Waage, Anders.
(2015)
Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA.
Blood
Sammendrag/abstract
-
Rustad, Even Holth;
Dai, Hong Yan;
Hov, Håkon;
Coward, Eivind;
Beisvag, Vidar;
Myklebost, Ola.
(2015)
BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis.
Blood Cancer Journal
Vitenskapelig artikkel
-
Holien, Toril;
Misund, Kristine;
Olsen, Oddrun Elise;
Baranowska, Katarzyna Anna;
Buene, Glenn;
Børset, Magne.
(2015)
MYC amplifications in myeloma cell lines: Correlation with MYC-inhibitor efficacy.
OncoTarget
Vitenskapelig artikkel
2014
-
Holien, Toril;
Misund, Kristine;
Buene, Glenn;
Olsen, Oddrun Elise;
Baranowska, Katarzyna Anna;
Waage, Anders.
(2014)
MYC gene copy number determine MYC expression and sensitivity to a MYC-inhibitor in multiple myeloma cells.
Cancer Research
Sammendrag/abstract
-
Rø, Torstein Baade;
Slørdahl, Tobias Schmidt;
Abdollahi, Pegah;
Vansemb, Esten;
Hagen, Lars;
Baranowska, Katarzyna Anna.
(2014)
PRL-3 Mediates Survival of Primary Myeloma Cells.
Blood
Sammendrag/abstract
-
Selvik, Linn-Karina M.;
Rao, Shalini;
Steigedal, Tonje;
Haltbakk, Ildri;
Misund, Kristine;
Bruland, Torunn.
(2014)
Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.
PLOS ONE
Vitenskapelig artikkel
-
Olsen, Oddrun Elise;
Wader, Karin Fahl;
Misund, Kristine;
Våtsveen, Thea Kristin;
Rø, Torstein Baade;
Mylin, Anne K..
(2014)
Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
Blood Cancer Journal
Vitenskapelig artikkel
2013
-
Müller, Rebekka;
Misund, Kristine;
Holien, Toril;
Bachke, Siri;
Gilljam, Karin Margaretha;
Våtsveen, Thea Kristin.
(2013)
Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells.
PLOS ONE
Vitenskapelig artikkel
-
Misund, Kristine;
Selvik, Linn-Karina M.;
Rao, Shalini;
Nørsett, Kristin Gabestad;
Bakke, Ingunn;
Sandvik, Arne.
(2013)
NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells.
PLOS ONE
Vitenskapelig artikkel
-
Holien, Toril;
Olsen, Oddrun Elise;
Misund, Kristine;
Hella, Hanne;
Waage, Anders;
Rø, Torstein Baade.
(2013)
Lymphoma and myeloma cells are highly sensitive to growth arrest and apoptosis induced by artesunate.
European Journal of Haematology
Vitenskapelig artikkel
-
Selvik, Linn-Karina M.;
Fjeldbo, Christina Sæten;
Flatberg, Arnar;
Steigedal, Tonje;
Misund, Kristine;
Anderssen, Endre.
(2013)
The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis.
BMC Genomics
Vitenskapelig artikkel
-
Misund, Kristine;
Baranowska, Katarzyna Anna;
Holien, Toril;
Rampa, Christoph Samuel;
Klein, Dionne;
Børset, Magne.
(2013)
A method for measurement of drug sensitivity of myeloma cells co-cultured with bone marrow stromal cells.
Journal of Biomolecular Screening
Vitenskapelig artikkel
-
Follin-Arbelet, Virginie;
Torgersen, Maria Lyngaas;
Naderi, Elin Hallan;
Misund, Kristine;
Sundan, Anders;
Blomhoff, Heidi Kiil.
(2013)
Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway.
Cancer Letters
Vitenskapelig artikkel
-
Rø, Torstein Baade;
Holien, Toril;
Fagerli, Unn-Merete;
Hov, Håkon;
Misund, Kristine;
Waage, Anders.
(2013)
HGF and IGF-1 synergize with SDF-1α in promoting migration of myeloma cells by cooperative activation of p21-activated kinase.
Experimental Hematology
Vitenskapelig artikkel
2012
-
Misund, Kristine;
Baranowska, Katarzyna Anna;
Holien, Toril;
Rampa, Christoph Samuel;
Klein, Dionne;
Børset, Magne.
(2012)
A Method for Measurement of Drug Sensitivity of Myeloma Cells Co-Cultured with Bone Marrow Stromal Cells.
Blood
Sammendrag/abstract
-
Slørdahl, Tobias Schmidt;
Misund, Kristine;
Rø, Torstein Baade;
Børset, Magne.
(2012)
PRL-3 Regulates Myeloma Cell Survival, Proliferation, Adhesion and Migration.
Blood
Sammendrag/abstract
2010
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Günther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje;
Thommesen, Liv.
(2010)
Functional studies on RNA-transfected cell microarrays.
Methods in molecular biology
Vitenskapelig artikkel
2008
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Gunther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje;
Thommesen, Liv.
(2008)
Functional studies on transfected cell microarray analysed by linear regression modelling.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Günther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje Strømmen;
Thommesen, Liv.
(2008)
Functional studies on transfected cell microarray analysed by linear regression modelling.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
2007
-
Steigedal, Tonje Strømmen;
Bruland, Torunn;
Misund, Kristine;
Thommesen, Liv;
Lægreid, Astrid.
(2007)
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Vitenskapelig artikkel
-
Misund, Kristine;
Steigedal, Tonje Strømmen;
Lægreid, Astrid;
Thommesen, Liv.
(2007)
Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A.
Journal of Cellular Biochemistry
Vitenskapelig artikkel
-
Sætre, Rune;
Ranang, Martin Thorsen;
Steigedal, Tonje Strømmen;
Stunes, Kamilla;
Misund, Kristine;
Thommesen, Liv.
(2007)
Webprot : online mining and annotation of biomedical literature using Google.
Nova Science Publishers
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
-
Steigedal, Tonje;
Bruland, Torunn;
Misund, Kristine;
Thommesen, Liv;
Lægreid, Astrid.
(2007)
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Vitenskapelig artikkel
-
Misund, Kristine;
Steigedal, Tonje;
Lægreid, Astrid;
Thommesen, Liv.
(2007)
Inducible cAMP early repressor splice variants ICER I and II gamma both repress transcription of c-fos and chromogranin A.
Journal of Cellular Biochemistry
Vitenskapelig artikkel
2003
-
Misund, Kristine.
(2003)
Studier av transkripsjonsrepressoren ICER sin funksjon i regulering av CRE-styrt genuttrykk.
[Mangler utgivernavn]
Hovedfagsoppgave
Tidsskriftspublikasjoner
-
Mestvedt, Ingvild Bergdal;
Menu, Eline;
Misund, Kristine;
Slørdahl, Tobias Schmidt;
Rasheed, Kashif;
Wolowczyk, Camilla Izabel.
(2025)
Novel SLAMF1-derived peptide induces apoptosis in multiple myeloma cells by targeting IRF4 transcription factor for degradation.
bioRxiv
Vitenskapelig artikkel
-
Behsen, Alenka Djarmila;
Vandsemb, Esten Nymoen;
Slørdahl, Tobias Schmidt;
Dybkær, Karen;
Jakobsen, Maja Zimmer;
Kashif, Muhammad.
(2025)
T cell phenotype and clonality changes in myeloma patients with short overall survival.
JCI Insight
Vitenskapelig artikkel
-
Berg, Sigrid Ravn;
Demirovic, Aida;
Sharma, Animesh;
Hagen, Lars;
Vågbø, Cathrine Broberg;
Zatula, Alexey.
(2024)
Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens.
Journal of Translational Medicine
Vitenskapelig artikkel
-
Behsen, Alenka Djarmila;
Holien, Toril;
Micci, Francesca;
Rye, Morten Beck;
Rasmussen, Jenny Malm;
Andersen, Kristin.
(2024)
Cell surface marker heterogeneity in human myeloma cell lines for modeling of disease and therapy.
Scientific Reports
Vitenskapelig artikkel
-
Jakobsen, Theresa;
Pløen, Gro Grunnet;
Behsen, Alenka Djarmila;
Møller, Holger Jon;
Plesner, Torben;
Dybkær, Karen.
(2024)
The Prognostic Potential of circRNAs in Multiple Myeloma: Insights From Whole Bone Marrow and Purified Plasma Cells.
Journal of Cellular and Molecular Medicine
Vitenskapelig artikkel
-
Aass, Kristin Roseth;
Tryggestad, Synne Stokke;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Nedal, Tonje Marie Vikene;
Misund, Kristine.
(2023)
IL-32 is induced by activation of toll-like receptors in multiple myeloma cells.
Frontiers in Immunology
Vitenskapelig artikkel
-
Behsen, Alenka Djarmila;
Vandsemb, Esten Nymoen;
Slørdahl, Tobias Schmidt;
Hjorth-Hansen, Henrik;
Quist-Paulsen, Petter;
Misund, Kristine.
(2023)
A patient with minimal myeloma treatment who survived for 20 years.
Haematologica
Vitenskapelig artikkel
-
Steiro, Ida Johnsen;
Vandsemb, Esten Nymoen;
Elsaadi, Samah;
Misund, Kristine;
Sponaas, Anne-Marit;
Børset, Magne.
(2022)
The serine protease matriptase inhibits migration and proliferation in multiple myeloma cells.
OncoTarget
Vitenskapelig artikkel
-
Giliberto, Mariaserena;
Miranda Santana, Leonardo;
Holien, Toril;
Misund, Kristine;
Nakken, Sigve;
Vodak, Daniel.
(2022)
Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines.
Frontiers in Oncology
Vitenskapelig artikkel
-
Misund, Kristine;
Hofste op Bruinink, Davine;
Coward, Eivind;
Hoogenboezem, Remco M.;
Rustad, Even Holth;
Sanders, Mathijs A..
(2022)
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence.
Leukemia
Vitenskapelig artikkel
-
Håland, Erling;
Moen, Ingrid Nyhus;
Veidal, Elias;
Hella, Hanne;
Misund, Kristine;
Slørdahl, Tobias Schmidt.
(2021)
TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan.
OncoTarget
Vitenskapelig artikkel
-
Aass, Kristin Roseth;
Mjelle, Robin;
Kastnes, Martin Haugrud;
Tryggestad, Synne Stokke;
van den Brink, Luca Mare;
Roseth, Ingrid Aass.
(2021)
Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells.
iScience
Vitenskapelig artikkel
-
Sponaas, Anne-Marit;
Waage, Anders;
Vandsemb, Esten;
Misund, Kristine;
Børset, Magne;
Sundan, Anders.
(2021)
Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?.
Frontiers in Immunology
Vitenskapelig oversiktsartikkel/review
-
Abdollahi, Pegah;
Vandsemb, Esten;
Elsaadi, Samah;
Røst, Lisa Marie;
Yang, Rui;
Hjort, Magnus Aassved.
(2021)
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma.
The FASEB Journal
Vitenskapelig artikkel
-
Westhrin, Marita;
Kovcic, Vlado;
Zejian, Zhang;
Moen, Siv Helen;
Nedal, Tonje Marie Vikene;
Bondt, Albert.
(2020)
Monoclonal immunoglobulins promote bone loss in multiple myeloma.
Blood
Vitenskapelig artikkel
-
Yang, Rui;
Elsaadi, Samah;
Misund, Kristine;
Abdollahi, Pegah;
Vandsemb, Esten;
Moen, Siv Helen.
(2020)
Conversion of ATP to adenosine by CD39 and CD73 in multiple myeloma can be successfully targeted together with adenosine receptor A2A blockade.
Journal for ImmunoTherapy of Cancer (JITC)
Vitenskapelig artikkel
-
Rustad, Even Holth;
Misund, Kristine;
Bernard, Elsa;
Coward, Eivind;
Yellapantula, Venkata D;
Hultcrantz, Malin.
(2019)
Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma.
American Journal of Hematology
Vitenskapelig artikkel
-
Misund, Kristine.
(2019)
Forekomst og betydning av MYC-translokasjoner i sykdomsforløpet ved myelomatose.
Bestpractice Onkologi/Hematologi
Fagartikkel
-
Misund, Kristine;
Keane, Niamh;
Stein, Caleb;
Asmann, Yan;
Day, Grady;
Welsh, Seth.
(2019)
MYC dysregulation in the progression of multiple myeloma.
Leukemia
Vitenskapelig artikkel
-
Olsen, Oddrun Elise;
Sankar, Meenu;
Elsaadi, Samah;
Hella, Hanne;
Buene, Glenn;
Darvekar, Sagar.
(2018)
BMPR2 inhibits activin and BMP signaling via wild-type ALK2.
Journal of Cell Science
Vitenskapelig artikkel
-
Misund, Kristine;
Hofste op Bruinink, Davine;
Coward, Eivind;
Hoogenboezem, Remco;
Rustad, Even Holth;
Hovig, Eivind.
(2018)
Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse.
Blood
Sammendrag/abstract
-
Petrovic, Voin;
Nepal, Anala;
Olaisen, Camilla;
Bachke, Siri;
Hira, Jonathan;
Søgaard, Caroline Krogh.
(2018)
Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress.
Nutrients
Vitenskapelig artikkel
-
Holien, Toril;
Misund, Kristine;
Olsen, Oddrun Elise;
Baranowska, Katarzyna Anna;
Buene, Glenn;
Børset, Magne.
(2018)
Correction: MYC amplifications in myeloma cell lines: correlation
with MYC-inhibitor efficacy.
OncoTarget
Errata
-
Rustad, Even Holth;
Coward, Eivind;
Skytøen, Emilie R;
Misund, Kristine;
Holien, Toril;
Standal, Therese.
(2017)
Monitoring multiple myeloma by quantification of recurrent mutations in serum.
Haematologica
Vitenskapelig artikkel
-
Zahoor, Muhammad;
Westhrin, Marita;
Aass, Kristin Roseth;
Moen, Siv Helen;
Misund, Kristine;
Psonka-Antonczyk, Katarzyna Maria.
(2017)
Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss.
Blood Advances
Vitenskapelig artikkel
-
Tangen, Jon-Magnus;
Holien, Toril;
Mirlashari, Mohammad Reza;
Misund, Kristine;
Hetland, Geir.
(2017)
Cytotoxic Effect on Human Myeloma Cells and Leukemic Cells by the Agaricus blazei Murill Based Mushroom Extract, Andosan™.
BioMed Research International
Vitenskapelig artikkel
-
Baranowska, Katarzyna Anna;
Misund, Kristine;
Starheim, Kristian K.;
Holien, Toril;
Johansson, Ida;
Darvekar, Sagar.
(2016)
Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells.
OncoTarget
Vitenskapelig artikkel
-
Misund, Kristine;
Keane, Niamh;
Asmann, Yan;
Von Wier, Scott;
Riggs, Daniel;
Ahmann, Gregory.
(2016)
Complementary Activation of CCND, MYC, RAS and NFkB by Mutations in Multiple Myeloma.
Blood
Sammendrag/abstract
-
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Hjort, Magnus Aassved;
Misund, Kristine;
Holien, Toril;
Sponaas, Anne-Marit.
(2016)
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3.
Molecular Cancer Research
Vitenskapelig artikkel
-
Våtsveen, Thea Kristin;
Sponaas, Anne Marit;
Tian, Erming;
Zhang, Qing;
Misund, Kristine;
Sundan, Anders.
(2016)
Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro.
Journal of Hematology & Oncology
Vitenskapelig artikkel
-
Starheim, Kristian Kobbenes;
Holien, Toril;
Misund, Kristine;
Johansson, Ida;
Baranowska, Katarzyna Anna;
Sponaas, Anne Marit.
(2016)
Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells.
Blood Cancer Journal
Vitenskapelig artikkel
-
Slørdahl, Tobias Schmidt;
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Rampa, Christoph Samuel;
Misund, Kristine;
Baranowska, Katarzyna Anna.
(2016)
The phosphatase of regenerating liver-3 (PRL-3) is importantfor IL-6-mediated survival of myeloma cells.
OncoTarget
Vitenskapelig artikkel
-
Follin-Arbelet, Virginie;
Misund, Kristine;
Naderi, Elin Hallan;
Ugland, Hege Katrin;
Sundan, Anders;
Blomhoff, Heidi Kiil.
(2015)
The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM.
Scientific Reports
Vitenskapelig artikkel
-
Johansson, Ida;
Monsen, Vivi Anita Talstad;
Pettersen, Kristine;
Mildenberger, Jennifer;
Misund, Kristine;
Kaarniranta, Kai.
(2015)
The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells.
Autophagy
Vitenskapelig artikkel
-
Misund, Kristine;
Baranowska, Katarzyna Anna;
Holien, Toril;
Starheim, Kristian K.;
Johansson, Ida;
Buene, Glenn.
(2015)
Chloroquine potentiates Carfilzomib but not Bortezomib effects on myeloma cells.
Cancer Research
Sammendrag/abstract
-
Wang, Huabo;
Teriete, Peter;
Hu, Angela;
Raveendra-Panickar, Dhanya;
Pendelton, Kelsey;
Lazo, John S.
(2015)
Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids.
OncoTarget
Vitenskapelig artikkel
-
Rustad, Even Holth;
Dai, Hong Yan;
Coward, Eivind;
Misund, Kristine;
Sundan, Anders;
Waage, Anders.
(2015)
Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA.
Blood
Sammendrag/abstract
-
Rustad, Even Holth;
Dai, Hong Yan;
Hov, Håkon;
Coward, Eivind;
Beisvag, Vidar;
Myklebost, Ola.
(2015)
BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis.
Blood Cancer Journal
Vitenskapelig artikkel
-
Holien, Toril;
Misund, Kristine;
Olsen, Oddrun Elise;
Baranowska, Katarzyna Anna;
Buene, Glenn;
Børset, Magne.
(2015)
MYC amplifications in myeloma cell lines: Correlation with MYC-inhibitor efficacy.
OncoTarget
Vitenskapelig artikkel
-
Holien, Toril;
Misund, Kristine;
Buene, Glenn;
Olsen, Oddrun Elise;
Baranowska, Katarzyna Anna;
Waage, Anders.
(2014)
MYC gene copy number determine MYC expression and sensitivity to a MYC-inhibitor in multiple myeloma cells.
Cancer Research
Sammendrag/abstract
-
Rø, Torstein Baade;
Slørdahl, Tobias Schmidt;
Abdollahi, Pegah;
Vansemb, Esten;
Hagen, Lars;
Baranowska, Katarzyna Anna.
(2014)
PRL-3 Mediates Survival of Primary Myeloma Cells.
Blood
Sammendrag/abstract
-
Selvik, Linn-Karina M.;
Rao, Shalini;
Steigedal, Tonje;
Haltbakk, Ildri;
Misund, Kristine;
Bruland, Torunn.
(2014)
Salt-inducible kinase 1 (SIK1) is induced by gastrin and inhibits migration of gastric adenocarcinoma cells.
PLOS ONE
Vitenskapelig artikkel
-
Olsen, Oddrun Elise;
Wader, Karin Fahl;
Misund, Kristine;
Våtsveen, Thea Kristin;
Rø, Torstein Baade;
Mylin, Anne K..
(2014)
Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin.
Blood Cancer Journal
Vitenskapelig artikkel
-
Müller, Rebekka;
Misund, Kristine;
Holien, Toril;
Bachke, Siri;
Gilljam, Karin Margaretha;
Våtsveen, Thea Kristin.
(2013)
Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells.
PLOS ONE
Vitenskapelig artikkel
-
Misund, Kristine;
Selvik, Linn-Karina M.;
Rao, Shalini;
Nørsett, Kristin Gabestad;
Bakke, Ingunn;
Sandvik, Arne.
(2013)
NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells.
PLOS ONE
Vitenskapelig artikkel
-
Holien, Toril;
Olsen, Oddrun Elise;
Misund, Kristine;
Hella, Hanne;
Waage, Anders;
Rø, Torstein Baade.
(2013)
Lymphoma and myeloma cells are highly sensitive to growth arrest and apoptosis induced by artesunate.
European Journal of Haematology
Vitenskapelig artikkel
-
Selvik, Linn-Karina M.;
Fjeldbo, Christina Sæten;
Flatberg, Arnar;
Steigedal, Tonje;
Misund, Kristine;
Anderssen, Endre.
(2013)
The duration of gastrin treatment affects global gene expression and molecular responses involved in ER stress and anti-apoptosis.
BMC Genomics
Vitenskapelig artikkel
-
Misund, Kristine;
Baranowska, Katarzyna Anna;
Holien, Toril;
Rampa, Christoph Samuel;
Klein, Dionne;
Børset, Magne.
(2013)
A method for measurement of drug sensitivity of myeloma cells co-cultured with bone marrow stromal cells.
Journal of Biomolecular Screening
Vitenskapelig artikkel
-
Follin-Arbelet, Virginie;
Torgersen, Maria Lyngaas;
Naderi, Elin Hallan;
Misund, Kristine;
Sundan, Anders;
Blomhoff, Heidi Kiil.
(2013)
Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway.
Cancer Letters
Vitenskapelig artikkel
-
Rø, Torstein Baade;
Holien, Toril;
Fagerli, Unn-Merete;
Hov, Håkon;
Misund, Kristine;
Waage, Anders.
(2013)
HGF and IGF-1 synergize with SDF-1α in promoting migration of myeloma cells by cooperative activation of p21-activated kinase.
Experimental Hematology
Vitenskapelig artikkel
-
Misund, Kristine;
Baranowska, Katarzyna Anna;
Holien, Toril;
Rampa, Christoph Samuel;
Klein, Dionne;
Børset, Magne.
(2012)
A Method for Measurement of Drug Sensitivity of Myeloma Cells Co-Cultured with Bone Marrow Stromal Cells.
Blood
Sammendrag/abstract
-
Slørdahl, Tobias Schmidt;
Misund, Kristine;
Rø, Torstein Baade;
Børset, Magne.
(2012)
PRL-3 Regulates Myeloma Cell Survival, Proliferation, Adhesion and Migration.
Blood
Sammendrag/abstract
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Günther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje;
Thommesen, Liv.
(2010)
Functional studies on RNA-transfected cell microarrays.
Methods in molecular biology
Vitenskapelig artikkel
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Gunther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje;
Thommesen, Liv.
(2008)
Functional studies on transfected cell microarray analysed by linear regression modelling.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Fjeldbo, Christina Sæten;
Misund, Kristine;
Günther, Clara-Cecilie;
Langaas, Mette;
Steigedal, Tonje Strømmen;
Thommesen, Liv.
(2008)
Functional studies on transfected cell microarray analysed by linear regression modelling.
Nucleic Acids Research (NAR)
Vitenskapelig artikkel
-
Steigedal, Tonje Strømmen;
Bruland, Torunn;
Misund, Kristine;
Thommesen, Liv;
Lægreid, Astrid.
(2007)
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Vitenskapelig artikkel
-
Misund, Kristine;
Steigedal, Tonje Strømmen;
Lægreid, Astrid;
Thommesen, Liv.
(2007)
Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A.
Journal of Cellular Biochemistry
Vitenskapelig artikkel
-
Steigedal, Tonje;
Bruland, Torunn;
Misund, Kristine;
Thommesen, Liv;
Lægreid, Astrid.
(2007)
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression.
American Journal of Physiology - Gastrointestinal and Liver Physiology
Vitenskapelig artikkel
-
Misund, Kristine;
Steigedal, Tonje;
Lægreid, Astrid;
Thommesen, Liv.
(2007)
Inducible cAMP early repressor splice variants ICER I and II gamma both repress transcription of c-fos and chromogranin A.
Journal of Cellular Biochemistry
Vitenskapelig artikkel
Del av bok/rapport
-
Sætre, Rune;
Ranang, Martin Thorsen;
Steigedal, Tonje Strømmen;
Stunes, Kamilla;
Misund, Kristine;
Thommesen, Liv.
(2007)
Webprot : online mining and annotation of biomedical literature using Google.
Nova Science Publishers
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
Rapport
-
Misund, Kristine.
(2003)
Studier av transkripsjonsrepressoren ICER sin funksjon i regulering av CRE-styrt genuttrykk.
[Mangler utgivernavn]
Hovedfagsoppgave
Undervisning
Emner
Formidling
2024
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PosterAndersson-Rusch, Clara; Quist-Løkken, Ingrid; Sætrom, Pål; Hanif, Md Abu; Rolinski, Milosz; Møen, Johanna. (2024) Whole genome CRISPR knockout screen reveals key function for ID3 in regulating myeloma cell survival via TCF3 and c-MYC. FASEB TGF-β Superfamily , Niagara Falls, NY 2024-07-21 - 2024-07-25
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PosterMestvedt, Ingvild Bergdal; Yurchenko, Maria; Espevik, Terje; Standal, Therese; Wolowczyk, Camilla Izabel; Rasheed, Kashif. (2024) Exploring peptide derived from Signaling Lymphocytic Activation Molecule Family 1 as novel treatment for multiple myeloma. EORTC NCI and AACR (ENA) ENA 2024 Symposium on molecular targets and cancer therapeutics , Barcelona 2024-10-23 - 2024-10-25
2023
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PosterAndersson-Rusch, Clara Leticia; Quist-Løkken, Ingrid; Sætrom, Pål; Beisvag, Vidar; Rolinski, Milosz; Møen, Johanna. (2023) Genome-Wide CRISPR/Cas9 Knock-out Screen Identifies Apoptosis-Relevant Genes in Multiple Myeloma. American Society of Hematology 65th ASH Annual Meeting and Exposition 2023-12-09 - 2023-12-12
2022
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Vitenskapelig foredragBehsen, Alenka Djarmila; Vandsemb, Esten Nymoen; Waage, Anders; Slørdahl, Tobias Schmidt; Sponaas, Anne Marit; Misund, Kristine. (2022) Altered composition of CD8 T cell subsets over time in the bone marrow of multiple myeloma patients with long- and short-term disease control. International Myeloma Society (IMS) International Myeloma Society Annual Meeting , Los Angeles, CA, USA 2022-08-25 - 2022-08-27
2021
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Vitenskapelig foredragBehsen, Alenka Djarmila; Vandsemb, Esten Nymoen; Waage, Anders; Slørdahl, Tobias Schmidt; Sponaas, Anne-Marit; Misund, Kristine. (2021) Altered composition of CD8 T cells subsets over time in the bone marrow of multiple myeloma patients with long-term disease control and short-term disease control. Nordic Myeloma Study Group NMSG Meeting , Stockholm 2021-09-16 - 2021-09-17
2018
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PosterMisund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind. (2018) Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. American Society of Hematology (ASH) 2018 2018-12-01 - 2018-12-04
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Vitenskapelig foredragMisund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind. (2018) Clonal Evolution of Multiple Myeloma After Treatment with Novel Agents . 2nd. International NTNU Symposium on Current and Future Clinical Biomarkers of Cancer 2018-06-14 - 2018-06-15
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Vitenskapelig foredragMisund, Kristine. (2018) Next-generation sequencing - Status og Nyheter. Nyheter inom myelom med ett multidisciplinärt fokus – Ny diagnostik, next generation sequenzing, högrisk myelom, uppdaterat vårdprogram, motivering av patienten etc. 2018-09-18 -
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PosterOlsen, Oddrun Elise; Sankar, Meenu; Elsaadi, Samah; Hella, Hanne; Darvekar, Sagar; Misund, Kristine. (2018) BMPR2 inhibits activin- and BMP-signaling via wild type ALK2. NTNU 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer: From diagnosis to immunotherapy – why is precision medicine so difficult? , Trondheim 2018-06-14 - 2018-06-15
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PosterYang, Rui; Elsaadi, Samah; Misund, Kristine; Slupphaug, Geir; Menu, Eline; Hay, Carl. (2018) Role of ectoenzymes CD39 and CD73 in the immune response to multiple myeloma . American Association for Cancer Research Annual Meeting of the American Association for Cancer Research , Chicago 2018-04-14 - 2018-04-18
2017
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Vitenskapelig foredragKeane, Niamh; Stein, Caleb; Angelov, Daniel; Tian, Shulan; Wiswanatha, David; Kumar, Shaji K.. (2017) MYC Translocations Identified By Sequencing Panel in Smoldering Multiple Myeloma Strongly Predict for Rapid Progression to Multiple Myeloma . American Society of Hematology American Society of Hematology 2017 , Atlanta 2017-12-09 - 2017-12-12
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Vitenskapelig foredragMisund, Kristine; Hofste op Bruinink, Davine; Coward, Eivind; Hoogenboezem, Remco; Rustad, Even Holth; Hovig, Eivind. (2017) Detection of mutations in Multiple Myeloma during different stages of disease. NMSG NMSG plenary meeting , Trondheim 2017-09-07 - 2017-09-08
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PosterCoward, Eivind; Misund, Kristine; Hofste op Bruinink, Davine; Hoogenboezem, Remco; Rustad, Even Holth; Myklebost, Ola. (2017) Exome sequencing of multiple myeloma at sequential time points. Barbara van Loon, IKM, NTNU Trondheim - Oslo Genome Dynamics Workshop , Trondheim 2017-06-15 - 2017-06-16
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Vitenskapelig foredragOlsen, Oddrun Elise; Sankar, Meenu; Darvekar, Sagar; Misund, Kristine; Sundan, Anders; Holien, Toril. (2017) Activins induce apoptosis through wild type ALK2/ACVR1 and are counteracted by BMPR2. FASEB The TGFb Superfamily: Signaling in Development and Disease , Lisboa 2017-07-09 - 2017-07-14
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Vitenskapelig foredragOlsen, Oddrun Elise; Sankar, Meenu; Elsaadi, Samah; Hella, Hanne; Darvekar, Sagar; Misund, Kristine. (2017) Activins induce apoptosis through wild type ALK2/ACVR1 and are counteracted by BMPR2. Nordic Myeloma Study Group NMSG plenary meeting , Trondheim 2017-09-07 - 2017-09-08
2016
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PosterRustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Standal, Therese. (2016) Circulating Tumor DNA in Multiple Myeloma . European Hematology Association European Hematology Association 21th Congress , Copenhagen 2016-06-09 - 2016-06-12
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Vitenskapelig foredragMisund, Kristine; Keane, Niamh; Asmann, Yan; Van Wier, Scott; Riggs, Daniel; Ahmann, Gregory. (2016) Complementary Activation of CCND, MYC, RAS and NFkB by Mutations in Multiple Myeloma. The American Society of Hematology 58th ASH Annual Meeting and Exposition , San Diego 2016-12-02 - 2016-12-06
2015
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PosterAbdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Rø, Torstein Baade; Slørdahl, Tobias Schmidt. (2015) PRL-3 increases survival of Multiple Myeloma cells through Src activation. 15th International Myeloma Workshop , Roma 2015-09-23 - 2015-09-25
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PosterMisund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Starheim, Kristian K.; Johansson, Ida; Buene, Glenn. (2015) Chloroquine potentiates Carfilzomib but not Bortezomib effects on myeloma cells. AACR 106th Annual Meeting 2015 , Philadelphia, PA 2015-04-18 - 2015-04-22
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Vitenskapelig foredragRustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Dai, Hong Yan. (2015) Exome sequencing of tumor samples as starting point for monitoring mutations in circulating DNA of patients with multiple myeloma. NCGC Norwegian Cancer Genomics Consortium (NCGC) Symposium , Oslo 2015-10-27 - 2015-10-28
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PosterRustad, Even Holth; Dai, Hong Yan; Coward, Eivind; Misund, Kristine; Sundan, Anders; Waage, Anders. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients By Digital PCR of Circulating DNA. The American Society of Hematology 57th ASH Annual Meeting and Exposition , Orlando 2015-12-05 - 2015-12-08
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Vitenskapelig foredragCoward, Eivind; Misund, Kristine; Rustad, Even Holth; Sundan, Anders; Waage, Anders. (2015) Mutations in multiple myeloma at sequential time points. Norsk kreftgenomikkonsortium NCGC Symposium 2015 , Losby Gods 2015-10-27 - 2015-10-28
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Vitenskapelig foredragRustad, Even Holth; Coward, Eivind; Skytøen, Emilie R; Misund, Kristine; Holien, Toril; Dai, Hong Yan. (2015) Detection and Monitoring of BRAF and NRAS Mutant Clones in Myeloma Patients by Digital PCR of Circulating DNA. NMSG Nordic Myeloma Study Group (NMSG) Annual Meeting , Stockholm 2015-11-12 - 2015-11-13
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Populærvitenskapelig foredragMisund, Kristine; Grøseth, Lill Anny Gunnes; Holien, Toril. (2015) Forskning på myelomatose. Klassebesøk, 3. trinn v.g.s. med fordypning i biologi 2015-03-18 - 2015-03-18
2014
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PosterRø, Torstein Baade; Slørdahl, Tobias Schmidt; Abdollahi, Pegah; Vansemb, Esten; Hagen, Lars; Baranowska, Katarzyna Anna. (2014) PRL-3 Mediates Survival of Primary Myeloma Cells. American Society of Hematology American Society of Hematology Annual Meeting , San Francisco 2014-12-06 - 2014-12-09
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Faglig foredragMisund, Kristine; Coward, Eivind; Waage, Anders. (2014) Norwegian Cancer Genomics Consortium - Multiple Myeloma projects. Norsk selskap for Hematolgi Høstmøte for Norsk selskap for Hematologi , Oslo 2014-11-04 - 2014-11-05
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Populærvitenskapelig foredragHolien, Toril; Grøseth, Lill Anny Gunnes; Standal, Therese; Misund, Kristine; Bruvoll, Ingrid; Nordrum, Ivar Skjåk. (2014) Hvordan jobber en kreftforsker + Besøk i medisinsk museum i Kunnskapssenteret. Klassebesøk, 5. trinn barneskole 2014-03-19 - 2014-03-19
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PosterHolien, Toril; Misund, Kristine; Buene, Glenn; Olsen, Oddrun Elise; Baranowska, Katarzyna Anna; Waage, Anders. (2014) MYC gene copy number determine MYC expression and sensitivity to a MYC-inhibitor in multiple myeloma cells. American Association for Cancer Research AACR Annual Meeting 2014 , San Diego, CA 2014-04-05 - 2014-04-09
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Intervju
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IntervjuMisund, Kristine. (2014) Får penger til tre års forskning. adressa nett og papir adressa nett og papir [Avis] 2014-10-29
2013
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PosterRao, Shalini; Thommesen, Liv; Nørsett, Kristin; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn. (2013) Nr4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. NBS Sør-Trøndelag Kontaktmøte Norsk Biokjemisk Selskap , Røros 2013-01-17 - 2013-01-20
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PosterOlsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Størdal, Berit Fladvad. (2013) Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. FASEB TGF-B Superfamily: Signaling in Development and Disease 2013-07-28 - 2013-08-02
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PosterRao, Shalini; Selvik, Linn-Karina M.; Nørsett, Kristin Gabestad; Bakke, Ingunn; Misund, Kristine; Bruland, Torunn. (2013) NR4A2 is regulated by gastrin and influences cellular responses in gastric adenocarcinoma cells. EMBO Conference Nuclear receptors: Linking molecules, genomes & physiology , Sorrento 2013-09-06 - 2013-09-10
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PosterSlørdahl, Tobias Schmidt; Misund, Kristine; Rø, Torstein Baade; Børset, Magne. (2013) The Phosphatase of Regenerating Liver-3 (PRL-3) Is Essential for IL-6-mediated Survival of Myeloma Cells. 14th International Myeloma Workshop , Kyoto 2013-04-03 - 2013-04-07
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Populærvitenskapelig foredragHolien, Toril; Sponaas, Anne-Marit; Misund, Kristine; Rø, Torstein Baade; Brede, Gaute; Standal, Therese. (2013) "Ta livet av kreftcellene" Stand i samarbeid med Kreftforeningen. NTNU - Forskningsdagene Forskningstorget , Trondheim 2013-09-20 - 2013-09-21
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Faglig foredragOlsen, Oddrun Elise; Wader, Karin Fahl; Misund, Kristine; Våtsveen, Thea Kristin; Rø, Torstein Baade; Størdal, Berit Fladvad. (2013) Membrane bound and soluble endoglin protects myeloma cells from bone morphogenetic protein 9 induced apoptosis. NBS vintermøte 2013-01-17 - 2013-01-20
2012
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PosterSlørdahl, Tobias Schmidt; Misund, Kristine; Rø, Torstein Baade; Børset, Magne. (2012) PRL-3 Regulates Myeloma Cell Survival, Proliferation, Adhesion and Migration. American Society of Hematology The 54th Annual Meeting of the American Society of Hematology (ASH) , Atlanta 2012-12-07 - 2012-12-11
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PosterMisund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Rampa, Christoph Samuel; Klein, Dionne; Børset, Magne. (2012) A Method for Measurement of Drug Sensitivity of Myeloma Cells Co-Cultured with Bone Marrow Stromal Cells. American Society of Hematology The American Society of Hematology (ASH) annual meeting , Atlanta, Georgia 2012-12-07 - 2012-12-11
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PosterMisund, Kristine; Baranowska, Katarzyna Anna; Holien, Toril; Rampa, Christoph Samuel; Waage, Anders; Sundan, Anders. (2012) Attempts to predict response to cytostatics in Multiple Myeloma patients. Norwegian Biochemical Society Norwegian Biochemical Society Contact Meeting , Storefjell 2012-01-19 - 2012-01-22
2010
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PosterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Fjeldbo, Christina Sæten; Flatberg, Arnar; Selvik, Linn-Karina M.. (2010) Exploring signal-induced cellular regulatory subnetworks by use of partial least square regression (PLSR) multidimensional analysis of gene expression time series data. The MGED Society 13th Annual MGED meeting , Boston, Massachusetts, USA , Boston 2010-07-13 - 2010-07-15
2009
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Vitenskapelig foredragBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten. (2009) Basic common architectural motifs underlying gastrin induced gene expression can be identified by dimention reduction methods. NBS Trondheim NBS 43. Contact Meeting , Røros 2009-01-17 - 2009-01-20
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PosterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Beisvag, Vidar; Sandvik, Arne Kristian; Thommesen, Liv. (2009) Discovering basic network motifs that underlie gastrin induced gene expression. ICSB The 10th International Conference on System Biology ICSB-2009, USA , Standford, Calefornia 2009-08-30 - 2009-09-04
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Vitenskapelig foredragSelvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje; Bruland, Torunn; Lægreid, Astrid. (2009) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response and is repressed by ICER and Zfp36l1. NBS NBS Kontaktmøte 2009 , Røros 2009-01-29 - 2009-02-01
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PosterAnderssen, Endre; Bruland, Torunn; Misund, Kristine; Sandvik, Arne K.; Thommesen, Liv; Lægreid, Astrid. (2009) Using basic networks motifs and biological background knowledge to analyze transcriptomic time series data. MGED Meeting , Phoenix, USA 2009-10-05 - 2009-10-08
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PosterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Beisvåg, Vidar; Sandvik, Arne K.; Lægreid, Astrid. (2009) Discovering basic network motifs that underlie gastrin induced gene expression. 10th international conference on system biology , San Francisco 2009-08-30 - 2009-09-04
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Vitenskapelig foredragThommesen, Liv; Misund, Kristine; Selvik, Linn Karina Myrland; Lægreid, Astrid; Bruland, Torunn. (2009) NR4A" (Nurr1) - involved in gastrin-mediated carcinogenesis?. Contact meeting NBS , Røros 2009-01-22 - 2009-01-25
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Vitenskapelig foredragBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Doseth, Berit; Langaas, Mette. (2009) Basic common architectural motifs underlying gastrin induced gene expression can be identified by dimension reduction methods. Contact Meeting NBS , Røros 2009-01-22 - 2009-01-25
2008
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PosterBruland, Torunn; Andersen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Fjeldbo, Christina Sæten; Lægreid, Astrid. (2008) Molecular mecanisms in cancer-related gastrin responses. Cancer Epigenetics , Boston 2008-05-28 - 2008-05-31
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PosterSelvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje Strømmen; Bruland, Torunn; Lægreid, Astrid. (2008) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response. ESF Functional Genomics and Disease , Innsbruck 2008-10-01 - 2008-10-05
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PosterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje Strømmen; Doseth, Berit; Fjeldbo, Christina Sæten. (2008) Significance analysis of gastrin-mediated transcription using dimension reduction methods for interpreting and modelling DNA microarray time series gene expression data. ESF Functional Genomics and Disease , Innsbruck 2008-10-01 - 2008-10-05
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PosterMisund, Kristine; Selvik, Linn-Karina M.; Slettahjell Prestvik, Wenche; Thommesen, Liv. (2008) miRNA and mRNA expression in HEK cells with inducible expression of tumour repressor ICER. ESF Functional genomics and Diseases , Innsbruck, Austria 2008-10-01 - 2008-10-05
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PosterMisund, Kristine; Johansen, Alice; Selvik, Linn-Karina M.; Prestvik, Wenche Slettahjell; Thommesen, Liv. (2008) miRNA and mRNA expression in HEK cells with inducible expression of tumour suppressor ICER. Functional Genomics and Disease , Innsbruck, Austria 2008-10-01 - 2008-10-04
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PosterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten. (2008) Significance analysis of gastrin-mediated transcription using dimension reduction methods for interpreting and modelling DNA microarray time series gene expression. 3rd ESF Functional Genomics Conference; Functional genomics and disease , Insnsbruck 2008-10-01 - 2008-10-04
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PosterBruland, Torunn; Anderssen, Endre; Misund, Kristine; Steigedal, Tonje; Doseth, Berit; Fjeldbo, Christina Sæten. (2008) Molecular mechanisms in cancer related gastrin responses. American Association for Cancer Research Cancer Epigenetics Conference , Boston 2008-05-28 - 2008-05-31
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PosterSelvik, Linn-Karina M.; Misund, Kristine; Fjeldbo, Christina Sæten; Steigedal, Tonje; Bruland, Torunn; Lægreid, Astrid. (2008) Salt-inducible kinase 1 (SIK1) is involved in the gastrin-mediated growth response. ESF Functional Genomics and Disease Conference , Innsbruck 2008-10-01 - 2008-10-04
2007
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Vitenskapelig foredragSæten, Christina; Misund, Kristine; Steigedal, Tonje; Otterlei, Marit; Lægreid, Astrid; Thommesen, Liv. (2007) Complex functional studies in mammalian cells using transfected cell arrays. Norsk Biokjemisk Selskap (NBS) The Norwegian Bichemical Society 43. Contact Meeting , Lillehammer 2007-02-01 - 2007-02-04
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Vitenskapelig foredragSteigedal, Tonje; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor (ICER) suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. Norsk Biokjemisk Selskap The Norwegian Bichemical Society 43. Contact Meeting , Lillehammer 2007-02-01 - 2007-02-04
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PosterSæten, Christina; Misund, Kristine; Steigedal, Tonje Strømmen; Lægreid, Astrid; Thommesen, Liv; Bruland, Torunn. (2007) Complex functional studies in mammalian cells using transfected cell arrays. Norsk Biokjemisk Selskaps 43. kontaktmøte , Lillehammer 2007-02-01 - 2007-02-04
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PosterSteigedal, Tonje Strømmen; Bruland, Torunn; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2007) Inducible cAMP early repressor (ICER) suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression. Norsk Biokjemisk Selskaps 43. kontaktmøte , Lillehammer 2007-02-01 - 2007-02-04
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PosterMisund, Kristine; Hoel, Sunniva; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2007) Global gene expression in HEK 293 cells with controllable ICER I and IIg - overexpression. Norsk Biokjemisk Selskaps 43. kontaktmøte , Lillehammer 2007-02-01 - 2007-02-04
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PosterMisund, Kristine; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2007) Global gene expression in HEK 293 cells with controllable ICER I and II gamma overexpression. NBS kontaktmøte 2007 , Lillehammer 2007-02-01 - 2007-02-01
2006
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PosterMisund, Kristine; Hoel, Sunniva; Bruland, Torunn; Anderssen, Endre; Lægreid, Astrid; Thommesen, Liv. (2006) Global gene expression in HEK 293 cells with controllable ICER I or IIgamma overexpression. The Seventh International Conference on Systems Biology; ICSB 2006 2006-10-08 - 2006-10-13
2005
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PosterMisund, Kristine; Lægreid, Astrid; Thommesen, Liv. (2005) Constitutive and inducible expression of ICER in HEK 293. NBS kontaktmøte , Tromsø 2005-01-13 - 2005-01-16
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PosterSteigedal, Tonje Strømmen; Bruland, Torunn; Ween, Ola; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2005) Function of splice variants of the transcriptional repressor ICER in gastrin-mediated reponses. NBS kontaktmøte , Tromsø 2005-01-13 - 2005-01-16
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Vitenskapelig foredragNørsett, K; Bruland, Torunn; Ween, Ola; Hofsli, Eva; Thommesen, Liv; Misund, Kristine. (2005) Systems biology of the normal and diseased gastrointestinal system. 2nd ESF Function genomics and disease , Oslo 2005-09-06 - 2005-09-10
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Vitenskapelig foredragNørsett, Kristin; Bruland, Torunn; Ween, Ola; Hofsli, Eva; Thommesen, Liv; Misund, Kristine. (2005) Systems biology of the normal and diseased gastrointestinal system. 2nd ESF Functional Genomics Conference 2005-01-10 - 2005-01-13
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Vitenskapelig foredragMisund, Kristine; Lægreid, Astrid; Thommesen, Liv. (2005) Constitutive and inducible expression of ICER in HEK 293. Kontaktmøtet Norsk Biokjemisk Selskap 2005 2005-01-13 - 2005-01-16
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PosterSteigedal, Tonje S.; Bruland, Torunn; Ween, Ola; Misund, Kristine; Thommesen, Liv; Lægreid, Astrid. (2005) Function of splice variants of the transcriptional repressor ICER in gastrin-mediated responses. The Norwegian Biochemical Society 41st Contact Meeting 2005-01-13 - 2005-01-16
2004
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PosterMisund, Kristine; Stunes, Astrid Kamilla; Tømmerdal, Linda; Thommesen, Liv; Bruland, Torunn; Lægreid, Astrid. (2004) Constitutive expression of ICER in the cell-line HEK 293. Kontaktmøtet Norsk Biokjemisk Selskap 2004 2004-01-15 - 2004-01-18
2003
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PosterThommesen, Liv; Lægreid, Astrid; Misund, Kristine. (2003) Constitutive expression of ICER in the human cell line AR42J. Kontaktmøtet Norsk Biokjemisk Selskap , Geilo 2003-01-23 - 2003-01-26
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PosterThommesen, Liv; Lægreid, Astrid; Misund, Kristine. (2003) Constitutive expression of ICER in the human cell line AR42J. Kontaktmøtet Norsk Biokjemisk Selskap , Geilo 2003-01-26 -