Katja Scheffler
Om
Leader of the Neurobiological Laboratory with a strong expertise in the field of aging, neurodegenerative disease, DNA repair, epigenetics, and translational medicine.
My research lab is situated at both St. Olavs Hospital and NTNU which allows conducting high-quality basic research as well as patient-oriented clinical studies.
Forskning
Neuroepigenetics - Base Modifications in Cognitive Function
Genomic DNA is continuously challenged by endogenous and exogenous oxidative agents, thus preserving genomic integrity is a key for development and health. Base excision repair (BER) is the major pathway for removal of oxidized bases in the genome. BER is initiated by DNA glycosylases, recognizing and excising a broad range of base lesions. However, processing of oxidized base lesions to avoid DNA mutations seems not the main activity of DNA glycosylases but they rather have a novel role in regulating the epigenetic landscape. The main focus of my research is to unravel the molecular mechanism and function of DNA glycosylases in epigenetic remodeling in brain, thus laying the basis for novel diagnostic- and therapeutic strategies for brain-related disorders.
Next-Generation Translational Medicine in Alzheimer's disease
AD is a complex age-related neurodegenerative disorder that affect millions of people worldwide. With the steady growth of life expectancy, AD has become one of the biggest health challenges of our society. The underlying mechanisms that contribute to the development and progression of AD are still not fully understood, and no treatment is available to halt or delay the disease. We aim to adress these challenges by etablishing a platform for patient-derived cell models to reveal novel molecular pathways leading to AD.
Publikasjoner
2025
-
Akdeniz, Bayram Cevdet;
Bahrami, Shahram;
Hagen, Espen;
Fuhrer, Julian;
Fominykh, Vera;
Shadrin, Alexey.
(2025)
Polygenic Hazard Score for Predicting Age-associated Risk of Alzheimer’s Disease in European Populations: Development and Validation.
medRxiv
Vitenskapelig artikkel
-
Abentung, Andreas;
Sakshaug, Teri;
Dumaru, Rabina;
Liabakk, Nina-Beate;
Yang, Mingyi;
Wang, Junbai.
(2025)
DNA glycosylases Ogg1 and Mutyh influence gene expression of PRC2 targets associated with cognition.
Cellular and Molecular Life Sciences (CMLS)
Vitenskapelig artikkel
-
Courtade, Sandra Monica Bach de;
Eikenes, Marte;
Sheng, Ying;
Nyman, Tuula Anneli;
Bliksrud, Yngve Thomas;
Scheffler, Katja.
(2025)
Identification of determinants for variability in mitochondrial biochemical complex activities.
Biochimica et Biophysica Acta - Bioenergetics
Vitenskapelig artikkel
-
Berrocal, Marion Silvana Fernández;
Reis, Amilcar;
Rolseth, Veslemøy;
Suganthan, Rajikala;
Kusnierczyk, Anna;
França, Arthur.
(2025)
NEIL3 influences adult neurogenesis and behavioral pattern separation via WNT signaling.
Cellular and Molecular Life Sciences (CMLS)
Vitenskapelig artikkel
2024
-
Obermann, Tobias;
Sakshaug, Teri Shearer;
Kanagaraj, Vishnu Vignesh;
Abentung, Andreas;
Sousa, Mirta Mittelstedt Leal de;
Hagen, Lars.
(2024)
Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH.
Redox Biology
Vitenskapelig artikkel
-
Neurauter, Christine Gran;
Pannone, Marco;
Sousa, Mirta;
Wang, Wei;
Kusnierczyk, Anna;
Luna, Luisa.
(2024)
Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Egiazarian, Milena Armenovna;
Abentung, Andreas;
Sakshaug, Teri;
Karabeika, Emily;
Hanumaihgari, Priyanka Reddy;
Grøntvedt, Gøril Rolfseng.
(2024)
The role of impaired oxidative base lesion repair in Alzheimer’s disease.
Alzheimer's & Dementia
Sammendrag/Abstract
2022
-
Egiazarian, Milena Armenovna;
Strømstad, Silje;
Sakshaug, Teri;
Nescolarde, Ana Beatriz Núñez;
Bethge, Nicole;
Bjørås, Magnar.
(2022)
Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Tari, Atefe R;
Berg, Helene Haugen;
Videm, Vibeke;
Bråthen, Geir;
White, Linda Rosemary;
Røsbjørgen, Ragnhild.
(2022)
Safety and efficacy of plasma transfusion from exercise - trained donors in patients with early Alzheimer’s disease: protocol for the ExPlas study.
BMJ Open
Fagartikkel
-
Grøntvedt, Gøril Rolfseng;
Sando, Sigrid Botne;
Lauridsen, Camilla;
Bråthen, Geir;
White, Linda Rosemary;
Salvesen, Øyvind.
(2022)
Association of Klotho protein levels and KL-VS heterozygosity with Alzheimer disease and amyloid and tau burden.
JAMA Network Open
Vitenskapelig artikkel
2021
-
Sousa, Mirta;
Ye, Jing;
Gomez, Luisa Fernanda Luna;
Hildrestrand, Gunn Annette;
Bjørås, Karine;
Scheffler, Katja.
(2021)
Impact of oxidative DNA damage and the role of DNA glycosylases in neurological dysfunction.
International Journal of Molecular Sciences
Vitenskapelig oversiktsartikkel/review
-
Hildrestrand, Gunn Annette;
Rolseth, Veslemøy;
Kunath, Nicolas;
Suganthan, Rajikala;
Jensen, Vidar;
Bugaj, Anna Maria.
(2021)
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice.
Communications Biology
Vitenskapelig artikkel
-
Quiles-Jiménez, Ana M T;
Gregersen, Ida;
Segers, Filip;
Skarpengland, Tonje;
Kroustallaki, Pinelopi;
Yang, Kuan.
(2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development.
Atherosclerosis
Vitenskapelig artikkel
2020
-
Farooq, Amna;
Grønmyr, Sindre;
Omer, Ali Avan;
Rognes, Torbjørn;
Scheffler, Katja;
Bjørås, Magnar.
(2020)
HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data.
Computational and Structural Biotechnology Journal
Vitenskapelig artikkel
-
Scheffler, Katja;
Jalland, Clara Maria Osnes;
Benestad, Sylvie L.;
Moldal, Torfinn;
Ersdal, Cecilie;
Gunnes, Gjermund.
(2020)
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease.
Free Radical Biology & Medicine
Vitenskapelig artikkel
2019
-
Scheffler, Katja;
Bjørås, Karine Øian;
Bjørås, Magnar.
(2019)
Diverse functions of DNA glycosylases processing oxidative base lesions in brain.
DNA Repair
Vitenskapelig oversiktsartikkel/review
-
Ystgaard, Martin Bogale;
Scheffler, Katja;
Suganthan, Rajikala;
Bjørås, Magnar;
Ranheim, Trine;
Sagen, Ellen Lund.
(2019)
Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy.
Neonatology
Vitenskapelig artikkel
2018
-
Scheffler, Katja;
Rachek, Lyudmila;
You, Panpan;
Rowe, Alexander D.;
Wang, Wei;
Kuśnierczyk, Anna.
(2018)
8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis.
DNA Repair
Vitenskapelig artikkel
2017
-
Rolseth, Veslemøy;
Gomez, Luisa Fernanda Luna;
Olsen, Ann-Karin;
Suganthan, Rajikala;
Scheffler, Katja;
Neurauter, Christine Gran.
(2017)
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.
Scientific Reports
Vitenskapelig artikkel
-
Olsen, Maria Belland;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Vinge, Leif Erik;
Alfsnes, Katrine;
Palibrk, Vuk.
(2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.
Cell reports
Vitenskapelig artikkel
2016
-
Skarpengland, Tonje;
Holm, Sverre;
Scheffler, Katja;
Gregersen, Ida;
Dahl, Tuva Børresdatter;
Suganthan, Rajikala.
(2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Scientific Reports
Vitenskapelig artikkel
-
Skarpengland, Tonje;
Dahl, Tuva Børresdatter;
Skjelland, Mona;
Scheffler, Katja;
Sousa, Mirta;
Gregersen, Ida.
(2016)
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Jalland, Clara Maria Osnes;
Scheffler, Katja;
Benestad, Sylvie Lafond;
Moldal, Torfinn;
Ersdal, Cecilie;
Gunnes, Gjermund.
(2016)
Neil3 induced neurogenesis protects against prion disease during the clinical phase.
Scientific Reports
Vitenskapelig artikkel
-
Palibrk, Vuk;
Suganthan, Rajikala;
Scheffler, Katja;
Wang, Wei;
Bjørås, Magnar;
Bøe, Stig Ove.
(2016)
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic–ischemic encephalopathy model.
Cell Death & Disease
Vitenskapelig artikkel
-
Wang, Wei;
Scheffler, Katja;
Esbensen, Qin Ying;
Eide, Lars.
(2016)
Quantification of DNA Damage by Real-Time qPCR.
Faglig kapittel
2015
-
Bjørge, Monica Dahl;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Suganthan, Rajikala;
Rolseth, Veslemøy;
Kusnierczyk, Anna.
(2015)
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.
Cell reports
Vitenskapelig artikkel
-
Wang, Wei;
Esbensen, Qin Ying;
Scheffler, Katja;
Eide, Lars.
(2015)
Analysis of Mitochondrial DNA and RNA Integrity by a Real-Time qPCR-Based Method.
Faglig kapittel
2014
-
Strand, Janne Maren;
Scheffler, Katja;
Bjørås, Magnar;
Eide, Lars.
(2014)
The distribution of DNA damage is defined by region-specific susceptibility to DNA damage formation rather than repair differences.
DNA Repair
Vitenskapelig artikkel
-
Wang, Wei;
Scheffler, Katja;
Esbensen, Qin Ying;
Strand, Janne Maren;
Stewart, James B.;
Bjørås, Magnar.
(2014)
Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.
PLOS ONE
Vitenskapelig artikkel
-
Jalland, Clara;
Benestad, Sylvie Lafond;
Ersdal, Cecilie;
Scheffler, Katja;
Suganthan, Rajikala;
Nakabeppu, Yusaku.
(2014)
Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Strand, Janne Maren;
Skinnes, Ragnhild;
Scheffler, Katja;
Rootwelt, Terje;
Woldseth, Berit;
Bjørås, Magnar.
(2014)
Genome instability in Maple Syrup Urine Disease correlates with impaired mitochondrial biogenesis.
Metabolism: Clinical and Experimental
Vitenskapelig artikkel
2012
-
Halsne, Ruth;
Esbensen, Qin Ying;
Wang, Wei;
Scheffler, Katja;
Suganthan, Rajikala;
Bjørås, Magnar.
(2012)
Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis.
DNA Repair
Vitenskapelig artikkel
Tidsskriftspublikasjoner
-
Akdeniz, Bayram Cevdet;
Bahrami, Shahram;
Hagen, Espen;
Fuhrer, Julian;
Fominykh, Vera;
Shadrin, Alexey.
(2025)
Polygenic Hazard Score for Predicting Age-associated Risk of Alzheimer’s Disease in European Populations: Development and Validation.
medRxiv
Vitenskapelig artikkel
-
Abentung, Andreas;
Sakshaug, Teri;
Dumaru, Rabina;
Liabakk, Nina-Beate;
Yang, Mingyi;
Wang, Junbai.
(2025)
DNA glycosylases Ogg1 and Mutyh influence gene expression of PRC2 targets associated with cognition.
Cellular and Molecular Life Sciences (CMLS)
Vitenskapelig artikkel
-
Courtade, Sandra Monica Bach de;
Eikenes, Marte;
Sheng, Ying;
Nyman, Tuula Anneli;
Bliksrud, Yngve Thomas;
Scheffler, Katja.
(2025)
Identification of determinants for variability in mitochondrial biochemical complex activities.
Biochimica et Biophysica Acta - Bioenergetics
Vitenskapelig artikkel
-
Berrocal, Marion Silvana Fernández;
Reis, Amilcar;
Rolseth, Veslemøy;
Suganthan, Rajikala;
Kusnierczyk, Anna;
França, Arthur.
(2025)
NEIL3 influences adult neurogenesis and behavioral pattern separation via WNT signaling.
Cellular and Molecular Life Sciences (CMLS)
Vitenskapelig artikkel
-
Obermann, Tobias;
Sakshaug, Teri Shearer;
Kanagaraj, Vishnu Vignesh;
Abentung, Andreas;
Sousa, Mirta Mittelstedt Leal de;
Hagen, Lars.
(2024)
Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH.
Redox Biology
Vitenskapelig artikkel
-
Neurauter, Christine Gran;
Pannone, Marco;
Sousa, Mirta;
Wang, Wei;
Kusnierczyk, Anna;
Luna, Luisa.
(2024)
Enhanced glutathione levels confer resistance to apoptotic and ferroptotic programmed cell death in NEIL DNA glycosylase deficient HAP1 cells.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Egiazarian, Milena Armenovna;
Abentung, Andreas;
Sakshaug, Teri;
Karabeika, Emily;
Hanumaihgari, Priyanka Reddy;
Grøntvedt, Gøril Rolfseng.
(2024)
The role of impaired oxidative base lesion repair in Alzheimer’s disease.
Alzheimer's & Dementia
Sammendrag/Abstract
-
Egiazarian, Milena Armenovna;
Strømstad, Silje;
Sakshaug, Teri;
Nescolarde, Ana Beatriz Núñez;
Bethge, Nicole;
Bjørås, Magnar.
(2022)
Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Tari, Atefe R;
Berg, Helene Haugen;
Videm, Vibeke;
Bråthen, Geir;
White, Linda Rosemary;
Røsbjørgen, Ragnhild.
(2022)
Safety and efficacy of plasma transfusion from exercise - trained donors in patients with early Alzheimer’s disease: protocol for the ExPlas study.
BMJ Open
Fagartikkel
-
Grøntvedt, Gøril Rolfseng;
Sando, Sigrid Botne;
Lauridsen, Camilla;
Bråthen, Geir;
White, Linda Rosemary;
Salvesen, Øyvind.
(2022)
Association of Klotho protein levels and KL-VS heterozygosity with Alzheimer disease and amyloid and tau burden.
JAMA Network Open
Vitenskapelig artikkel
-
Sousa, Mirta;
Ye, Jing;
Gomez, Luisa Fernanda Luna;
Hildrestrand, Gunn Annette;
Bjørås, Karine;
Scheffler, Katja.
(2021)
Impact of oxidative DNA damage and the role of DNA glycosylases in neurological dysfunction.
International Journal of Molecular Sciences
Vitenskapelig oversiktsartikkel/review
-
Hildrestrand, Gunn Annette;
Rolseth, Veslemøy;
Kunath, Nicolas;
Suganthan, Rajikala;
Jensen, Vidar;
Bugaj, Anna Maria.
(2021)
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice.
Communications Biology
Vitenskapelig artikkel
-
Quiles-Jiménez, Ana M T;
Gregersen, Ida;
Segers, Filip;
Skarpengland, Tonje;
Kroustallaki, Pinelopi;
Yang, Kuan.
(2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development.
Atherosclerosis
Vitenskapelig artikkel
-
Farooq, Amna;
Grønmyr, Sindre;
Omer, Ali Avan;
Rognes, Torbjørn;
Scheffler, Katja;
Bjørås, Magnar.
(2020)
HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data.
Computational and Structural Biotechnology Journal
Vitenskapelig artikkel
-
Scheffler, Katja;
Jalland, Clara Maria Osnes;
Benestad, Sylvie L.;
Moldal, Torfinn;
Ersdal, Cecilie;
Gunnes, Gjermund.
(2020)
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Scheffler, Katja;
Bjørås, Karine Øian;
Bjørås, Magnar.
(2019)
Diverse functions of DNA glycosylases processing oxidative base lesions in brain.
DNA Repair
Vitenskapelig oversiktsartikkel/review
-
Ystgaard, Martin Bogale;
Scheffler, Katja;
Suganthan, Rajikala;
Bjørås, Magnar;
Ranheim, Trine;
Sagen, Ellen Lund.
(2019)
Neuromodulatory effect of NLRP3 and ASC in neonatal hypoxic ischemic encephalopathy.
Neonatology
Vitenskapelig artikkel
-
Scheffler, Katja;
Rachek, Lyudmila;
You, Panpan;
Rowe, Alexander D.;
Wang, Wei;
Kuśnierczyk, Anna.
(2018)
8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis.
DNA Repair
Vitenskapelig artikkel
-
Rolseth, Veslemøy;
Gomez, Luisa Fernanda Luna;
Olsen, Ann-Karin;
Suganthan, Rajikala;
Scheffler, Katja;
Neurauter, Christine Gran.
(2017)
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.
Scientific Reports
Vitenskapelig artikkel
-
Olsen, Maria Belland;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Vinge, Leif Erik;
Alfsnes, Katrine;
Palibrk, Vuk.
(2017)
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.
Cell reports
Vitenskapelig artikkel
-
Skarpengland, Tonje;
Holm, Sverre;
Scheffler, Katja;
Gregersen, Ida;
Dahl, Tuva Børresdatter;
Suganthan, Rajikala.
(2016)
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Scientific Reports
Vitenskapelig artikkel
-
Skarpengland, Tonje;
Dahl, Tuva Børresdatter;
Skjelland, Mona;
Scheffler, Katja;
Sousa, Mirta;
Gregersen, Ida.
(2016)
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Jalland, Clara Maria Osnes;
Scheffler, Katja;
Benestad, Sylvie Lafond;
Moldal, Torfinn;
Ersdal, Cecilie;
Gunnes, Gjermund.
(2016)
Neil3 induced neurogenesis protects against prion disease during the clinical phase.
Scientific Reports
Vitenskapelig artikkel
-
Palibrk, Vuk;
Suganthan, Rajikala;
Scheffler, Katja;
Wang, Wei;
Bjørås, Magnar;
Bøe, Stig Ove.
(2016)
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic–ischemic encephalopathy model.
Cell Death & Disease
Vitenskapelig artikkel
-
Bjørge, Monica Dahl;
Hildrestrand, Gunn Annette;
Scheffler, Katja;
Suganthan, Rajikala;
Rolseth, Veslemøy;
Kusnierczyk, Anna.
(2015)
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.
Cell reports
Vitenskapelig artikkel
-
Strand, Janne Maren;
Scheffler, Katja;
Bjørås, Magnar;
Eide, Lars.
(2014)
The distribution of DNA damage is defined by region-specific susceptibility to DNA damage formation rather than repair differences.
DNA Repair
Vitenskapelig artikkel
-
Wang, Wei;
Scheffler, Katja;
Esbensen, Qin Ying;
Strand, Janne Maren;
Stewart, James B.;
Bjørås, Magnar.
(2014)
Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age.
PLOS ONE
Vitenskapelig artikkel
-
Jalland, Clara;
Benestad, Sylvie Lafond;
Ersdal, Cecilie;
Scheffler, Katja;
Suganthan, Rajikala;
Nakabeppu, Yusaku.
(2014)
Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage.
Free Radical Biology & Medicine
Vitenskapelig artikkel
-
Strand, Janne Maren;
Skinnes, Ragnhild;
Scheffler, Katja;
Rootwelt, Terje;
Woldseth, Berit;
Bjørås, Magnar.
(2014)
Genome instability in Maple Syrup Urine Disease correlates with impaired mitochondrial biogenesis.
Metabolism: Clinical and Experimental
Vitenskapelig artikkel
-
Halsne, Ruth;
Esbensen, Qin Ying;
Wang, Wei;
Scheffler, Katja;
Suganthan, Rajikala;
Bjørås, Magnar.
(2012)
Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis.
DNA Repair
Vitenskapelig artikkel
Del av bok/rapport
-
Wang, Wei;
Scheffler, Katja;
Esbensen, Qin Ying;
Eide, Lars.
(2016)
Quantification of DNA Damage by Real-Time qPCR.
Faglig kapittel
-
Wang, Wei;
Esbensen, Qin Ying;
Scheffler, Katja;
Eide, Lars.
(2015)
Analysis of Mitochondrial DNA and RNA Integrity by a Real-Time qPCR-Based Method.
Faglig kapittel
Undervisning
Veiledning
I have experience in supervising master students, medical research line students and PhD students.
Formidling
2025
-
Vitenskapelig foredragScheffler, Katja. (2025) From Bench to Bedside: Targeting DNA glycosylase OGG1 in Alzheimer’s disease. 8th EU-US Conference on Endogenous DNA Damage and Repair , Trondheim 2025-10-04 - 2025-10-07
-
Vitenskapelig foredragScheffler, Katja. (2025) The TrønderBrain project – Next-generation translational medicine. Alzheimer's Disease Translational conference , Trondheim 2025-09-09 - 2025-09-11
2024
-
PosterNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A personalized in vitro metabolic model of preclincal Alzheimer's disease. The Aging Brain Conference , Union Hotel Geiranger 2024-06-12 - 2024-06-14
-
Vitenskapelig foredragNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A Personalized in vitro Metabolic Model of Preclinical Alzheimer’s Disease. 15th International Conference on Brain Energy Metabolism (ICBEM) , Grand Hotel Union in Ljubljana, Slovenia 2024-09-17 - 2024-09-21
-
Vitenskapelig foredragScheffler, Katja. (2024) Trønderbrain- Next-generation translational medicine in Alzheimer's disease. 4th Nordic Neuroscience conference , Copenhagen 2024-01-15 - 2024-01-17
-
PosterJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2024) Development of a Translational Metabolic Platform for Brain Disorders, Exemplified by Preclinical Alzheimer's Disease. 4th Nordic Neuroscience Meeting 2024-01-15 - 2024-01-17
-
PosterEgiazarian, Milena Armenovna; Abentung, Andreas; Karabeika, Emily; Hanumaihgari, Priyanka; Schnur, Paulina; Hovland, Oline Øie. (2024) The role of impaired oxidative base lesion repair in Alzheimer's disease. Alzheimer's Association International Conference 2024-07-28 - 2024-08-01
2023
-
Vitenskapelig foredragJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2023) Investigation of Metabolism in Cerebral Organoids Derived from Patients with Preclinical Alzheimer's Disease. Frampeik 2023-09-30 - 2023-09-30
-
PosterSakshaug, Teri; Salvesen, Hedda Kjelsaas; Scheffler, Katja. (2023) The role of oxidative DNA damage and repair on the neuroepigenome in stress-mediated depression and anxiety. 10th Annual NRSN PhD Conference 2023-09-27 - 2023-09-29