Björn Gustafsson
Bakgrunn og aktiviteter
Björn Gustafsson er professor i fordøyelsessykdommer ved Institutt for klinisk og molekylær medisin.
Björn Gustafssons forskningsvirksomhet har vært fokusert på medisinsk molekylærbiologi og klinisk forskning hovedsakelig innen nevroendokrin kreft i mage-tarm systemet, nevroendokrinologi og inflammatorisk tarmsykdom. Han har i mange år hatt et nært forskningssamarbeid med Yale School of Medicine i USA og var også gjesteforsker ved Yale 2007-2008.
Gustafsson var prodekan for forskning ved Det medisinske fakultet fra 2012-2015 og dekan fra 2015-2020. Han var leder for Norsk Gastroenterologisk Forening 2009-2013.
Gustafsson studerte medisin i Lund i Sverige. Han flyttet med sin familie til Norge i 1997 og har utført sin legespesialisering og forskerutdanning i Trondheim.
Vitenskapelig, faglig og kunstnerisk arbeid
Et utvalg av nyere tidsskriftspublikasjoner, kunstneriske produksjoner, bok, inklusiv bokdeler og rapport-del. Se alle publikasjoner i databasen
Tidsskriftspublikasjoner
- (2020) The serotonin reuptake transporter is reduced in the epithelium of active Crohn's disease and ulcerative colitis. American Journal of Physiology - Gastrointestinal and Liver Physiology. vol. 319 (6).
- (2020) Intestinal epithelial cells express immunomodulatory ISG15 during active ulcerative colitis and Crohn's disease. Journal of Crohn's and Colitis. vol. 14 (7).
- (2018) Not only stem cells, but also mature cells, particularly neuroendocrine cells, may develop into tumours: time for a paradigm shift. Therapeutic Advances in Gastroenterology. vol. 11.
- (2018) Tu1753 - type 1 Interferon Signaling in Intestinal Epithelial Cells During Active Inflammatory Bowel Disease. Gastroenterology. vol. 154 (6).
- (2016) Cellular localization of guanylin and uroguanylin mRNAs in human and rat duodenal and colonic mucosa. Cell and Tissue Research. vol. 365 (2).
- (2015) The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease. Scandinavian Journal of Gastroenterology. vol. 50 (10).
- (2014) The PAS positive material in gastric cancer cells of signet ring type is not mucin. Experimental and molecular pathology (Print). vol. 96 (3).
- (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases. vol. 20 (6).
- (2013) Relevance of TNBS-Colitis in Rats: A Methodological Study with Endoscopic, Historical and Transcripttomic Characterization and Correlation to IBD. PLOS ONE. vol. 8 (1).
- (2013) Su1771 Reduced Guanylate Cyclase C Signaling in IBD May Sustain Inflammation, Epithelial Barrier Dysfunction and Increase Cancer Risk in IBD. Gastroenterology. vol. 144 (5).
- (2013) The Stimulatory Adenosine Receptor ADORA2B Regulates Serotonin (5-HT) Synthesis and Release in Oxygen-Depleted EC Cells in Inflammatory Bowel Disease. PLOS ONE. vol. 8 (4).
- (2013) Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis. PLOS ONE. vol. 8 (2).
- (2013) REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation. Cell and Tissue Research. vol. 352 (3).
- (2013) Gastric Carcinoids (Neuroendocrine Neoplasms). Gastroenterology Clinics of North America. vol. 42 (2).
- (2013) In situ hybridization in human and rodent tissue by the use of a new and simplified method. Applied immunohistochemistry & molecular morphology (Print). vol. 21 (2).
- (2012) Tu1912 Endoscopic, Histological and Transcriptomic Characterization of TNBS-Colitis in Rats, a Model for IBD. Gastroenterology. vol. 142.
- (2012) The role of mechanical forces and adenosine in the regulation of intestinal enterochromaffin cell serotonin secretion. American Journal of Physiology - Gastrointestinal and Liver Physiology. vol. 302 (3).
- (2012) Dissecting the IBD Transcriptome. Inflammatory Bowel Diseases. vol. 18.
- (2012) Differential signal pathway activation and 5-HT function: the role of gut enterochromaffin cells as oxygen sensors. American Journal of Physiology - Gastrointestinal and Liver Physiology. vol. 303 (10).
- (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science. vol. 103 (7).