2021

• Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate; Olsen, Lene Christin; Chawla, Konika; Aas, Per Arne; Sætrom, Pål. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports. volum 11:18952.
  Vitenskapelig artikkel
• Kavli, Bodil Merete; Iveland, Tobias Solli; Buchinger, Edith; Hagen, Lars; Liabakk, Nina-Beate; Aas, Per Arne; Obermann, Tobias Sebastian; Aachmann, Finn Lillelund; Slupphaug, Geir. (2021) RPA2 winged-helix domain facilitates UNG-mediated removal of uracil from ssDNA; implications for repair of mutagenic uracil at the replication fork. Nucleic Acids Research (NAR). volum 49 (7).
  Vitenskapelig artikkel
• Steen, Kristian Wollen; Hagen, Lars; Vågbø, Cathrine Broberg; Rabe, Renana; Iveland, Tobias Solli; Aas, Per Arne; Sharma, Animesh; Sporsheim, Bjørnar; Erlandsen, Hilde; Palibrk, Vuk; Bjørås, Magnar; Fonseca, Davi de Miranda; Mosammaparast, Nima; Slupphaug, Geir. (2021) ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA. Journal of Translational Medicine. volum 19 (1).
  Vitenskapelig artikkel

2020

• Ianevski, Aleksandr; Yao, Rouan; Biza, Svetlana; Zusinaite, Eva; Mannik, Andres; Kivi, Gaily; Planken, Anu; Kurg, Kristiina; Tombak, Eva-Maria; Ustav, Mart Jr; Shtaida, Nastassia; Kulesskiy, Evgeny; Jo, Eunji; Yang, Jaewon; Lysvand, Hilde; Løseth, Kirsti; Oksenych, Valentyn; Aas, Per Arne; Tenson, Tanel; Vitkauskienė, Astra; Windisch, Marc P; Fenstad, Mona H.; Nordbø, Svein Arne; Ustav, Mart; Bjørås, Magnar; Kainov, Denis. (2020) Identification and Tracking of Antiviral Drug Combinations. Viruses. volum 12 (10).
  Vitenskapelig artikkel
• Ianevski, Aleksandr; Yao, Rouan; Fenstad, Mona H.; Biza, Svetlana; Zusinaite, Eva; Reisberg, Tuuli; Lysvand, Hilde; Løseth, Kirsti; Landsem, Veslemøy Malm; Fossum, Janne; Erlandsen, Sten Even; Aas, Per Arne; Hagen, Lars; Pettersen, Caroline Hild; Tenson, Tanel; Afset, Jan Egil; Nordbø, Svein Arne; Bjørås, Magnar; Kainov, Denis; Oksenych, Valentyn. (2020) Potential Antiviral Options against SARS-CoV-2 Infection. Viruses. Viruses.
  Vitenskapelig artikkel
• Yang, Mingyi; Lin, Xiaolin; Segers, Filip; Suganthan, Rajikala; Hildrestrand, Gunn Annette; Rinholm, Johanne Egge; Aas, Per Arne; Sousa, Mirta; Holm, Sverre; Bolstad, Nils; Warren, David; Berge, Rolf Kristian; Johansen, Rune Forstrøm; Yndestad, Arne; Kristiansen, Elise; Klungland, Arne; Gomez, Luisa Fernanda Luna; Eide, Lars; Halvorsen, Bente; Aukrust, Pål; Bjørås, Magnar. (2020) OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation. Cell reports. volum 30 (12).
  Vitenskapelig artikkel

2019

• Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin; Kunath, Nicolas; Otterlei, Marit; Sætrom, Pål; Bjørås, Magnar; Samson, Leona D.; van Loon, Barbara. (2019) Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nature Communications. volum 10 (1).
  Vitenskapelig artikkel
• Sarno, Antonio; Lundbæk, Marie Benner; Liabakk, Nina-Beate; Aas, Per Arne; Mjelle, Robin; Hagen, Lars; Sousa, Mirta; Krokan, Hans Einar; Kavli, Bodil Merete. (2019) Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil. Nucleic Acids Research (NAR). volum 47 (9).
  Vitenskapelig artikkel

2018

• Dewan, Alisa Elinsdatter; Xing, Mengtan; Lundbæk, Marie Benner; Gago-Fuentes, Raquel; Beck, Carole; Aas, Per Arne; Liabakk, Nina-Beate; Sæterstad, Siri; Chau, Khac Thanh Phong; Kavli, Bodil Merete; Oksenych, Valentyn. (2018) Robust DNA repair in PAXX-deficient mammalian cells. FEBS Open Bio. volum 8 (3).
  Vitenskapelig artikkel

2017

• Buchinger, Edith; Wiik, Siv Åshild; Kusnierczyk, Anna; Rabe, Renana; Aas, Per Arne; Kavli, Bodil Merete; Slupphaug, Geir; Aachmann, Finn Lillelund. (2017) Backbone 1H, 13C and 15N chemical shift assignment of full-length human uracil DNA glycosylase UNG2. Biomolecular NMR Assignments. volum 12 (1).
  Vitenskapelig artikkel

2015

• Mjelle, Robin; Hegre, Siv Anita; Aas, Per Arne; Slupphaug, Geir; Drabløs, Finn; Sætrom, Pål; Krokan, Hans Einar. (2015) Cell cycle regulation of human DNA repair and chromatin remodeling genes. DNA Repair. volum 30.
  Vitenskapelig artikkel
• Pettersen, Henrik Sahlin; Galashevskaya, Anastasia; Doseth, Berit; Sousa, Mirta; Sarno, Antonio; Visnes, Torkild; Aas, Per Arne; Liabakk, Nina-Beate; Slupphaug, Geir; Sætrom, Pål; Kavli, Bodil Merete; Krokan, Hans Einar. (2015) AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature. DNA Repair. volum 25.
  Vitenskapelig artikkel
• Zub, Kamila; Sousa, Mirta; Sarno, Antonio; Sharma, Animesh; Dikic, Aida; Rao, Shalini; Young, Clifford; Aas, Per Arne; Ericsson, Ida; Sundan, Anders; Jensen, Ole Nørregaard; Slupphaug, Geir. (2015) Modulation of cell metabolic pathways and oxidative stress signaling contribute to acquired Melphalan resistance in multiple myeloma cells. PLOS ONE. volum 10 (3).
  Vitenskapelig artikkel

2014

• Hagen, Lars; Sharma, Animesh; Aas, Per Arne; Slupphaug, Geir. (2014) Off-target responses in the HeLa proteome subsequent to transient plasmid-mediated transfection. Biochimica et Biophysica Acta - Proteins and Proteomics. volum 1854 (1).
  Vitenskapelig artikkel
• Krokan, Hans Einar; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Kavli, Bodil Merete; Slupphaug, Geir. (2014) Error-free versus mutagenic processing of genomic uracil-Relevance to cancer. DNA Repair. volum 19.
  Vitenskapelig artikkel
• Wallenius, Anders; Hauser, Jannek; Aas, Per Arne; Sarno, Antonio; Kavli, Bodil Merete; Krokan, Hans Einar; Grundström, Thomas. (2014) Expression and recruitment of uracil-DNA glycosylase are regulated by E2A during antibody diversification. Molecular Immunology. volum 60 (1).
  Vitenskapelig artikkel

2013

• Diaz, Javier Pena; Hegre, Siv Anita; Anderssen, Endre; Aas, Per Arne; Mjelle, Robin; Gilfillan, Gregor Duncan; Lyle, Robert; Drabløs, Finn; Krokan, Hans Einar; Sætrom, Pål. (2013) Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication. Nucleic Acids Research (NAR). volum 41 (5).
  Vitenskapelig artikkel
• Galashevskaya, Anastasia; Sarno, Antonio; Vågbø, Cathrine Broberg; Aas, Per Arne; Hagen, Lars; Slupphaug, Geir; Krokan, Hans Einar. (2013) A robust, sensitive assay for genomic uracil determination by LC/MS/MS reveals lower levels than previously reported. DNA Repair. volum 12 (9).
  Vitenskapelig artikkel
• Hegre, Siv Anita; Sætrom, Pål; Aas, Per Arne; Pettersen, Henrik P Sahlin; Otterlei, Marit; Krokan, Hans Einar. (2013) Multiple microRNAs may regulate DNA repair enzyme uracil‐DNA glycosylase. DNA Repair. volum 12 (1).
  Vitenskapelig artikkel
• Krokan, Hans Einar; Kavli, Bodil Merete; Ericsson, Ida; Galashevskaya, Anastasia; Sarno, Antonio; Aas, Per Arne; Vagbo, CB; Pettersen, Henrik P Sahlin; Slupphaug, Geir. (2013) Genomic uracil - potent mutagen but normal intermediate in adaptive immunity. The FEBS Journal. volum 280.
  Sammendrag/abstract
• Sousa, Mirta; Zub, Kamila Anna; Aas, Per Arne; Hanssen-Bauer, Audun; Demirovic, Aida; Sarno, Antonio; Tian, Erming; Liabakk, Nina-Beate; Slupphaug, Geir. (2013) An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells. PLOS ONE. volum 8 (2).
  Vitenskapelig artikkel
• Vågbø, Cathrine Broberg; Svaasand, Eva Kathrine; Aas, Per Arne; Krokan, Hans Einar. (2013) Methylation damage to RNA induced in vivo in Escherichia coli is repaired by endogenous AlkB as part of the adaptive response. DNA Repair. volum 12 (3).
  Vitenskapelig artikkel

2010

• Fenstad, Mona Høysæter; Johnson, Matthew; Roten, Linda Tømmerdal; Aas, Per Arne; Forsmo, Siri; Klepper, Kjetil; East, Christine; Abraham, Lawrence j.; Blangero, John; Brennecke, Shaun P.; Austgulen, Rigmor; Moses, Eric K. (2010) Genetic and molecular functional characterization of variants within TNFSF13B, a positional candidate preeclampsia susceptibility gene on 13q. PLOS ONE. volum 5 (9).
  Vitenskapelig artikkel
• Krokan, Hans Einar; Kavli, Bodil Merete; Otterlei, Marit; Akbari, M.; Slupphaug, Geir; Aas, Per Arne. (2010) DNA repair and cancer. European Journal of Cancer. volum 8 (5).
  Sammendrag/abstract
• Monsen, Vivi A Talstad; Sundheim, Ottar; Aas, Per Arne; Westbye, Marianne Pedersen; Sousa, Mirta; Slupphaug, Geir; Krokan, Hans Einar. (2010) Divergent ß-hairpins determine double-strand versus single-strand substrate recognition of human AlkB-homologues 2 and 3. Nucleic Acids Research (NAR). volum 38 (19).
  Vitenskapelig artikkel

2009

• Aas, Per Arne; Diaz, Javier Pena; Liabakk, Nina-Beate; Krokan, Hans Einar; Skorpen, Frank. (2009) Overexpression of transcription factor AP-2 stimulates the P-A promoter of the human uracil-DNA glycosylase (UNG) gene through a mechanism involving derepression. DNA Repair. volum 8 (7).
  Vitenskapelig artikkel
• Gilljam, Karin Margaretha; Feyzi, Emadoldin; Aas, Per Arne; Sousa, Mirta; Müller, Rebekka; Vågbø, Cathrine Broberg; Catterall, Tara; Liabakk, Nina-Beate; Slupphaug, Geir; Drabløs, Finn; Krokan, Hans Einar; Otterlei, Marit. (2009) Identification of a novel, widespread, and functionally important PCNA-binding motif. Journal of Cell Biology. volum 186 (5).
  Vitenskapelig artikkel
• Langevin, C; Maidou-Peindara, P; Aas, Per Arne; Jacquot, G; Otterlei, Marit; Slupphaug, Geir; Benichou, S. (2009) Human Immunodeficiency Virus Type 1 Vpr Modulates Cellular Expression of UNG2 via a Negative Transcriptional Effect. Journal of Virology. volum 83 (19).
  Vitenskapelig artikkel

2008

• Westbye, Marianne; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Talstad, Vivi A; Kavli, Bodil Merete; Hagen, Lars; Sundheim, Ottar; Akbari, Mansour; Liabakk, Nina-Beate; Slupphaug, Geir; Otterlei, Marit; Krokan, Hans Einar. (2008) Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. Journal of Biological Chemistry. volum 238 (36).
  Vitenskapelig artikkel

2007

• Feyzi, Emadoldin; Aas, Per Arne; Sundheim, Ottar; Westbye, Marianne; Vågbø, Cathrine Broberg; Otterlei, Marit; Slupphaug, Geir; Krokan, Hans Einar. (2007) RNA Base Damage and Repair. Current Pharmaceutical Biotechnology. volum 8 (6).
  Vitenskapelig oversiktsartikkel/review

2006

• Ringvoll, Jeanette; Ringvoll, Jeanette; Nordstrand, Line M.; Vågbø, Cathrine Broberg; Vagbo, CB; Talstad, Vivi; Reite, Karen; Aas, Per Arne; Lauritzen, Knut H.; Liabakk, Nina-Beate; Bjørk, Alexandra; Doughty, Richard William; Falnes, Pål Ø.; Krokan, Hans Einar; Klungland, Arne. (2006) Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA. EMBO Journal. volum 25.
  Vitenskapelig artikkel
• Sundheim, Ottar; Vågbø, Cathrine Broberg; Bjørås, Magnar; Mittelstedt, L.Mirta; Talstad, Vivi; Aas, Per Arne; Drabløs, Finn; Krokan, Hans Einar; Tainer, John A.; Slupphaug, Geir. (2006) Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. EMBO Journal. volum 25.
  Vitenskapelig artikkel

2004

• Akbari, Mansour; Otterlei, Marit; Diaz, Javier Pena; Aas, Per Arne; Kavli, Bodil; Liabakk, Nina-Beate; Hagen, Lars; Imai, K; Durandy, A; Slupphaug, Geir; Krokan, Hans Einar. (2004) Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells. Nucleic Acids Research (NAR). volum 32.
  Vitenskapelig artikkel
• Drabløs, Finn; Feyzi, Emadoldin; Aas, Per Arne; Vågbø, Cathrine Broberg; Kavli, Bodil; Bratlie, Marit Skyrud; Diaz, Javier Pena; Otterlei, Marit; Slupphaug, Geir; Krokan, Hans Einar. (2004) Alkylation damage in DNA and RNA - repair mechanisms and medical significance. DNA Repair. volum 3 (11).
  Vitenskapelig oversiktsartikkel/review
• Falnes, Pål; Bjørås, Magnar; Bjoras, M; Aas, PA; Sundheim, Ottar; Seeberg, E. (2004) Substrate specificities of bacterial and human AlkB proteins. Nucleic Acids Research (NAR). volum 30 (11).
  Vitenskapelig artikkel

2003

• Aas, Per Arne; Otterlei, Marit; Falnes, P.Ø; Vågbø, Cathrine; Skorpen, Frank; Akbari, Mansour; Sundheim, Ottar; Bjørås, Magnar; Slupphaug, Geir; Seeberg, Erling Christen; Krokan, Hans Einar. (2003) Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA. Nature. volum 421.
  Vitenskapelig artikkel

2002

• Kavli, Bodil; Sundheim, Ottar; Akbari, Mansour; Otterlei, Marit; Nilsen, Hilde; Skorpen, Frank; Aas, Per Arne; Hagen, Lars; Krokan, Hans Einar; Slupphaug, Geir. (2002) hUNG2 is the major repair enzyme for removal of uracil from U:A matchers,U:G mismatches and U in single stranded DNA, with SMUG1 as a broad specificity backup. Journal of Biological Chemistry. volum 18.
  Vitenskapelig artikkel

2001

• Krokan, Hans Einar; Otterlei, Marit; Nilsen, Hilde; Kavli, Bodil; Skorpen, Frank; Andersen, Sonja; Skjelbred, Camilla Furu; Akbari, Mansour; Aas, Per Arne; Slupphaug, Geir. (2001) Properties and Functions of Human Uracil-DNA Glycosylase from the UNG Gene. Progress in Nucleic Acid Research and Molecular Biology. volum 68.
  Vitenskapelig artikkel

2000

• Nilsen, Hilde; Steinsbekk, Kristin; Otterlei, Marit; Slupphaug, Geir; Aas, Per Arne; Krokan, Hans Einar. (2000) Analysis of uracil-DNA glycosylases from the murine UNG gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues. Nucleic Acids Research (NAR).
  Vitenskapelig artikkel
• Nilsen, Hilde; Steinsbekk, Kristin; Otterlei, Marit; Slupphaug, Geir; Aas, Per Arne; Krokan, Hans Einar. (2000) Analysis of uracil-DNA glycosylases from the murine Ung-gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologues. Nucleic Acids Research (NAR).
  Vitenskapelig artikkel

1999

• Otterlei, Marit; Warbrick, Emma; Nagelhus, Toril; Haug, Terje; Slupphaug, Geir; Akbari, Mansour; Aas, Per Arne; Steinsbekk, Kristin; Bakke, Oddmund; Krokan, Hans Einar. (1999) Post-replicative base excision repair in replication foci. EMBO Journal. volum 18 (13).
  Vitenskapelig artikkel

1998

• Haug, T.; Skorpen, Frank; Aas, P.A.; Malm, V; Skjelbred, Camilla; Krokan, Hans Einar. (1998) Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase. Nucleic Acids Research (NAR). volum 1998.
  Vitenskapelig artikkel
• Krokan, Hans Einar; Skorpen, Frank; Otterlei, Marit; Bharati, S; Steinsbekk, Kristin; Nilsen, Hilde; Nagelhus-Hernes, T; Haug, T; Aas, Per A; Akbari, M; Skjelbred, Camilla; Kavli, Bodil. (1998) Human uracil-DNA glycosylase:gene structure, regulation and structural basis for catalysis. 1998. DNA damage and repair: Oxygen Radical Effects, Cellular Prote ction and Biological Consequences..
  Fagbok
• Skorpen, Frank; Alm, B.; Skjelbred, Camilla; Aas, P.A.; Krokan, Hans Einar. (1998) Paracetamol increases sensitivity to ultraviolet (UV) irradiation, delays repair of the UNG-gene and recovery of RNA synthesis in HaCaT cells. Chemico-Biological Interactions.
  Vitenskapelig artikkel
• Skorpen, Frank; Skjelbred, Camilla; Aas, P.A.; Alm, B.; Schønberg, S.A.; Krokan, Hans Einar. (1998) Repair of cyclobutane pyrimidine dimers in the O6-methylguanine-DNA methyltransferase (MGMT) gene of MGMT proficient and deficient human cell lines and comparison with the repair of other genes and a repressed X-chromosomal locus. Mutation Research (DNA Repair).
  Vitenskapelig artikkel