Bakgrunn og aktiviteter
Utdannet anestesiolog og klinisk farmakolog. Arbeidet i St. Olavs hospital og Det medisinske fakultet, NTNU siden 1978. Nestleder forskning ved ISB. Har hatt 4 forskningopphold utlands.
Vitenskapelig, faglig og kunstnerisk arbeid
Et utvalg av nyere tidsskriftspublikasjoner, kunstneriske produksjoner, bok, inklusiv bokdeler og rapport-del. Se alle publikasjoner i databasen
Tidsskriftspublikasjoner
- (2018) Pharmacokinetics and -dynamics of intramuscular and intranasal naloxone: an explorative study in healthy volunteers. European Journal of Clinical Pharmacology.
- (2018) Pharmacodynamics and arteriovenous difference of intravenous naloxone in healthy volunteers exposed to remifentanil. European Journal of Clinical Pharmacology.
- (2017) International patent applications for non-injectable naloxone for opioid overdose reversal: Exploratory search and retrieve analysis of the PatentScope database. Drug and Alcohol Review. vol. 37 (2).
- (2017) Opioid education programs and nasal naloxone rescue kits in Europe. Toxicology Letters. vol. 280.
- (2017) Pharmacokinetics of a new, nasal formulation of naloxone. European Journal of Clinical Pharmacology. vol. 73 (5).
- (2016) Ethical issues and stakeholders matter. Addiction. vol. 111 (4).
- (2016) The rare Arg181Cys mutation in the μ opioid receptor can abolish opioid responses. Acta Anaesthesiologica Scandinavica. vol. 60 (8).
- (2015) Innate immune signalling genetics of pain, cognitive dysfunction and sickness symptoms in cancer pain patients treated with transdermal fentanyl. PLoS ONE. vol. 10:0137179 (9).
- (2015) Prevalence of use of non-prescription analgesics in the Norwegian HUNT3 population: Impact of gender, age, exercise and prescription of opioids. BMC Public Health. vol. 15.
- (2015) Consumption of and satisfaction with health care among opioid users with chronic non-malignant pain. Acta Anaesthesiologica Scandinavica. vol. 59 (10).
- (2015) Renal function and symptoms/adverse effects in opioid-treated patients with cancer. Acta Anaesthesiologica Scandinavica. vol. 59 (8).
- (2015) Biotilgjenglighet og effekt av nalokson som nesespray sammenliknet med intramuskulær injeksjon. NAForum. vol. 28 (3).
- (2014) Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study. Pharmacogenetics & Genomics. vol. 24 (4).
- (2014) Concentrations of remifentanil, propofol, fentanyl, and midazolam during rewarming from therapeutic hypothermia. Acta Anaesthesiologica Scandinavica. vol. 58 (6).
- (2014) Chronic pain and use of opioids: A population-based pharmacoepidemiological study from the Norwegian Prescription Database and the Nord-Trøndelag Health Study. Pain. vol. 155 (7).
- (2014) A pilot study of nasal fentanyl for patient controlled treatment of cancer pain. Journal of Opioid Management. vol. 10 (1).
- (2014) Biotilgjenglighet av nalokson som nesespray- grunnlaget for fremtidig prehospital bruk. NAForum. vol. 27 (3).
- (2013) Effects of hypothermia on the disposition of morphine, midazolam, fentanyl, and propofol in intensive care unit patients. Drug Metabolism And Disposition. vol. 41 (1).
- (2013) Variability in UDP-glucuronosyltransferase genes and morphine metabolism. Observations from a cross-sectional multicenter study in advanced cancer patients with pain. Pharmacogenetics & Genomics. vol. 23 (3).
- (2013) Current use of nitrous oxide in public hospitals in Scandinavian countries. Acta Anaesthesiologica Scandinavica. vol. 57 (9).