Bakgrunn og aktiviteter
Jeg er ansatt som forsker ved K. G. Jebsen - Senter for Hjertetrening. Mitt forskningfokus er kardiovaskulære tilpasninger til fysisk trening, fra cellulær fysiologi, via kliniske tilpasninger, til sammenhenger på befolkningsnivå.
Pågående forskningsprosjekter
- Hjertelilv: Organisering av en database med 6000 pasienter på hjerterehabilitering i Norge. I samarbeid med LHL.
- Generasjon-100: En randomisert kontrollert studie på langsiktige effekter av trening hos eldre mennesker.
- OptimEx: En EU-finansiert multisenterstudie med fokus på trening som medisin for hjertesvikt med bevart ejeksjonsfraksjon.
- Trening på mitokondriefunksjon ved røykebein og koronar hjertesykdom.
Arbeidsforhold
- Forsker ved Cardiac Exercise Research Group (CERG), Institutt for sirkulasjon og bildediagnostikk, NTNU, Trondheim.
- Forsker ved Nasjonal kompetansetjeneste Trening som medisin, St. Olavs Hospital, Trondheim.
- Seniorrådgiver ved Norwegian PhD-School of Heart Research (NORHEART), Universitetet i Oslo.
Utdannelse
- 2008: dr. philos, NTNU. Avhandling: "High-Intenstity exercise and Cardiovascular Health".
- 2000: cand. polit, NTNU. Avhandling: ”Effects of endurance training on muscle blood flow and metabolism studied in the isolated upper arm muscles”.
- 1998: cand. mag, NTNU. Emner innen idrettsvitenskap og biologi.
Vitenskapelig, faglig og kunstnerisk arbeid
Et utvalg av nyere tidsskriftspublikasjoner, kunstneriske produksjoner, bok, inklusiv bokdeler og rapport-del. Se alle publikasjoner i databasen
Tidsskriftspublikasjoner
- (2018) Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interactive Cardiovascular and Thoracic Surgery. vol. 27.
- (2017) High Intensity Interval Training for Maximizing Health Outcomes. Progress in cardiovascular diseases. vol. 60 (1).
- (2017) Cardiorespiratory Reference Data in Older Adults: The Generation 100 Study. Medicine & Science in Sports & Exercise. vol. 49 (11).
- (2017) Calf raise exercise increases walking performance in patients with intermittent claudication. Journal of Vascular Surgery. vol. 65 (5).
- (2017) Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function. Journal of Translational Medicine. vol. 15 (130).
- (2016) Comparison of three popular exercise modalities on VO2max in overweight and obese. Medicine & Science in Sports & Exercise. vol. 48 (3).
- (2016) Akutt trening før hjertekirurgi-kan det hjelpe mot operasjonsrelatert myokardskade?. Vitenskapelige forhandlinger / De norske kirurgiske foreninger.
- (2016) Mitochondrial respiration after one session of calf raise exercise in patients with peripheral vascular disease and healthy older adults. PLoS ONE. vol. 11:e0165038 (10).
- (2015) Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle. European Journal of Heart Failure. vol. 17 (3).
- (2015) How to Be 80 Year Old and Have a VO2max of a 35 Year Old. Case Reports in Medicine.
- (2015) A randomised controlled study of the long-term effects of exercise training on mortality in elderly people: Study protocol for the generation 100 study. BMJ Open. vol. 5 (2).
- (2015) CrossTalk proposal: High intensity interval training does have a role in risk reduction or treatment of disease. Journal of Physiology. vol. 593 (24).
- (2015) Effect of change in vo<inf>2</inf>max on daily total energy expenditure in a cohort of norwegian men: A randomized pilot study. Open Cardiovascular Medicine Journal. vol. 9.
- (2014) Effect of 24 sessions of high-intensity aerobic interval training carried out at either high or moderate frequency, a randomized trial. PLoS ONE. vol. 9 (2).
- (2014) The higher the better? Interval training intensity in coronary heart disease. Journal of Science and Medicine in Sport. vol. 17 (5).
- (2014) Comparison of left versus right atrial myocardium in patients with sinus rhythm or atrial fibrillation - an assessment of mitochondrial function and microRNA expression. Physiological Reports. vol. 2 (e12124).
- (2014) Mitochondrial respiration and microRNA expression in right and left atrium of patients with atrial fibrillation. Physiological Genomics. vol. 46 (14).
- (2014) Remote ischemic preconditioning preserves mitochondrial function and activates pro-survival protein kinase Akt in the left ventricle during cardiac surgery: A randomized trial. International Journal of Cardiology. vol. 177 (2).
- (2014) Remote ischemic preconditioning preserves mitochondrial function and influences myocardial MicroRNA expression in atrial myocardium during coronary bypass surgery. Circulation Research. vol. 114 (5).
- (2013) Deletion of mouse Alkbh7 leads to obesity. Journal of Molecular Cell Biology. vol. 5 (3).