Marianne Doré Hansen
Om
Current research project: Viruses and gut mucosal innate immune responses in inflammatory bowel diseases.
My research has been focused on molecular signaling mechanism in viral-host interaction with emphasize on inflammation, using hepatitis C virus (HCV), a human oncogenic virus, as a model of infection. My current research focus is on virus and gut mucosal innate immune responses in Inflammatory Bowel Disease (IBD) and how both pathogenic and commensal viruses may play a role in the establishment, exacerbation or remission of IBD.
Curriculum Vitae
- Researcher at Department of Clinical and Molecular Medicine, NTNU 2018 – now
- Visiting scientist at Institut Pasteur, Paris, France, Department of Virology, Hepacivirus and innate immunity, 2015 - 2018
- Post doctor at Department of Laboratory medicine, Children’s and Women’s Health, NTNU 2015-2018
- Visiting scientist at Institut Pasteur, Paris, France, Department of Virology, Hepacivirus and innate immunity, 2013
- PhD in Molecular Medicine in Marit W. Anthonsens lab, Department of Laboratory Medicine, Children’s and Women’s Health, NTNU, 2010-2015
- Senior Engineer, Department of Biology, NTNU, 2000-2010
- M.Sc. Biotechnology, University in Tromsø, 1996 – 1999
- B.Sc. (Chemistry), Sør-Trøndelag University College (HiST), Trondheim (1993 - 1996)
Publikasjoner
2024
-
Sæterstad, Siri;
Østvik, Ann Elisabeth;
Hansen, Marianne Dore;
Bruland, Torunn;
Granlund, Atle van Beelen.
(2024)
The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response.
Journal of Translational Medicine
Vitenskapelig artikkel
2023
-
Gopalakrishnan, Shreya;
Bakke, Ingunn;
Hansen, Marianne Dore;
Skovdahl, Helene Kolstad;
Granlund, Atle van Beelen;
Sandvik, Arne Kristian.
(2023)
Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids.
Frontiers in Immunology
Vitenskapelig artikkel
-
Hansen, Marianne Dore.
(2023)
Inflammatoriske tarmsykdommer og viromet.
Bioingeniøren
Populærvitenskapelig artikkel
2022
-
Gopalakrishnan, Shreya;
Hansen, Marianne Dore;
Skovdahl, Helene Kolstad;
Roseth, Ingrid Aass;
Granlund, Atle van Beelen;
Østvik, Ann Elisabet.
(2022)
Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium.
Frontiers in Immunology
Vitenskapelig artikkel
2021
-
Daussy, Coralie F.;
Monard, Sarah C.;
Guy, Coralie;
Muñoz-González, Sara;
Chazal, Maxime;
Anthonsen, Marit Walbye.
(2021)
The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the golgi apparatus during hepatitis C virus infection.
Journal of Virology
Vitenskapelig artikkel
-
Bruland, Torunn;
Østvik, Ann Elisabet;
Sandvik, Arne Kristian;
Hansen, Marianne Dore.
(2021)
Host-Viral Interactions in the Pathogenesis of Ulcerative Colitis.
International Journal of Molecular Sciences
Vitenskapelig oversiktsartikkel/review
2017
-
Dabo, Stephanie;
Maillard, Patrick;
Rodriguez, Milagros Collados;
Hansen, Marianne Dore;
Mazouz, Sabrina;
Bigot, Donna-Joe.
(2017)
Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT.
Scientific Reports
Vitenskapelig artikkel
-
Hansen, Marianne Dore;
Johnsen, Ingvild Bjellmo;
Stiberg, Kim Andre Ha;
Sherstova, Tatyana;
Wakita, Takaji;
Richard, Gabriel Mary.
(2017)
Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Vitenskapelig artikkel
-
Hansen, Marianne Dore.
(2017)
How hepatitis C wages guerrilla warfare.
Gemini.no
Populærvitenskapelig artikkel
2015
-
Hansen, Marianne Dore;
Anthonsen, Marit Walbye;
Johnsen, Ingvild Bjellmo.
(2015)
Interplay of single´stranded RNA viruses with autophagy: Intracellular mechanisms and functional impact.
NTNU Det medisinske fakultet
Doktorgradsavhandling
2014
-
Arukwe, Augustine;
Olufsen, Marianne Opsahl;
Cicero, Nicola;
Hansen, Marianne Dore.
(2014)
Effects on Development, Growth Responses and Thyroid-Hormone Systems in Eyed-Eggs and Yolk-Sac Larvae of Atlantic Salmon (Salmo salar) Continuously Exposed to 3,3′,4,4′-Tetrachlorobiphenyl (PCB-77).
Journal of Toxicology and Environmental Health, Part A
Vitenskapelig artikkel
2009
-
Kortner, Trond Moxness;
Mortensen, Anne Skjetne;
Hansen, Marianne Dore;
Arukwe, Augustine.
(2009)
Neural aromatase transcript and protein levels in Atlantic salmon (Salmo salar) are modulated by the ubiquitous water pollutant, 4-nonylphenol.
General and Comparative Endocrinology
Vitenskapelig artikkel
2005
-
Akbari, Mansour;
Hansen, Marianne Dore;
Halgunset, Jostein;
Skorpen, Frank;
Krokan, Hans Einar.
(2005)
Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner.
Journal of Molecular Diagnostics
Vitenskapelig artikkel
Tidsskriftspublikasjoner
-
Sæterstad, Siri;
Østvik, Ann Elisabeth;
Hansen, Marianne Dore;
Bruland, Torunn;
Granlund, Atle van Beelen.
(2024)
The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response.
Journal of Translational Medicine
Vitenskapelig artikkel
-
Gopalakrishnan, Shreya;
Bakke, Ingunn;
Hansen, Marianne Dore;
Skovdahl, Helene Kolstad;
Granlund, Atle van Beelen;
Sandvik, Arne Kristian.
(2023)
Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids.
Frontiers in Immunology
Vitenskapelig artikkel
-
Hansen, Marianne Dore.
(2023)
Inflammatoriske tarmsykdommer og viromet.
Bioingeniøren
Populærvitenskapelig artikkel
-
Gopalakrishnan, Shreya;
Hansen, Marianne Dore;
Skovdahl, Helene Kolstad;
Roseth, Ingrid Aass;
Granlund, Atle van Beelen;
Østvik, Ann Elisabet.
(2022)
Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium.
Frontiers in Immunology
Vitenskapelig artikkel
-
Daussy, Coralie F.;
Monard, Sarah C.;
Guy, Coralie;
Muñoz-González, Sara;
Chazal, Maxime;
Anthonsen, Marit Walbye.
(2021)
The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the golgi apparatus during hepatitis C virus infection.
Journal of Virology
Vitenskapelig artikkel
-
Bruland, Torunn;
Østvik, Ann Elisabet;
Sandvik, Arne Kristian;
Hansen, Marianne Dore.
(2021)
Host-Viral Interactions in the Pathogenesis of Ulcerative Colitis.
International Journal of Molecular Sciences
Vitenskapelig oversiktsartikkel/review
-
Dabo, Stephanie;
Maillard, Patrick;
Rodriguez, Milagros Collados;
Hansen, Marianne Dore;
Mazouz, Sabrina;
Bigot, Donna-Joe.
(2017)
Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT.
Scientific Reports
Vitenskapelig artikkel
-
Hansen, Marianne Dore;
Johnsen, Ingvild Bjellmo;
Stiberg, Kim Andre Ha;
Sherstova, Tatyana;
Wakita, Takaji;
Richard, Gabriel Mary.
(2017)
Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M.
Proceedings of the National Academy of Sciences of the United States of America (PNAS)
Vitenskapelig artikkel
-
Hansen, Marianne Dore.
(2017)
How hepatitis C wages guerrilla warfare.
Gemini.no
Populærvitenskapelig artikkel
-
Arukwe, Augustine;
Olufsen, Marianne Opsahl;
Cicero, Nicola;
Hansen, Marianne Dore.
(2014)
Effects on Development, Growth Responses and Thyroid-Hormone Systems in Eyed-Eggs and Yolk-Sac Larvae of Atlantic Salmon (Salmo salar) Continuously Exposed to 3,3′,4,4′-Tetrachlorobiphenyl (PCB-77).
Journal of Toxicology and Environmental Health, Part A
Vitenskapelig artikkel
-
Kortner, Trond Moxness;
Mortensen, Anne Skjetne;
Hansen, Marianne Dore;
Arukwe, Augustine.
(2009)
Neural aromatase transcript and protein levels in Atlantic salmon (Salmo salar) are modulated by the ubiquitous water pollutant, 4-nonylphenol.
General and Comparative Endocrinology
Vitenskapelig artikkel
-
Akbari, Mansour;
Hansen, Marianne Dore;
Halgunset, Jostein;
Skorpen, Frank;
Krokan, Hans Einar.
(2005)
Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner.
Journal of Molecular Diagnostics
Vitenskapelig artikkel
Rapport
-
Hansen, Marianne Dore;
Anthonsen, Marit Walbye;
Johnsen, Ingvild Bjellmo.
(2015)
Interplay of single´stranded RNA viruses with autophagy: Intracellular mechanisms and functional impact.
NTNU Det medisinske fakultet
Doktorgradsavhandling
Formidling
2018
-
Vitenskapelig foredragDaussy, Coralie F.; Monard, Sarah C.; Anthonsen, Marit Walbye; Dreux, M; Meurs, Eliane F.; Hansen, Marianne Dore. (2018) HCV infection triggers the IRGM-mediated Golgi fragmentation through the NLRP3 inflammasome. HCV2018 25th International Symposium on Hepatitis C virus and related viruses , Dublin 2018-10-08 - 2018-10-11
2017
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Vitenskapelig foredragHansen, Marianne Dore. (2017) Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. IKOM Seminar 2017-08-30 -
-
Vitenskapelig foredragHansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Sherstova, Tatyana; Wakita, Takaji; Richard, Gabriel Mary. (2017) Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. CFATG 7th Scientific days on autophagy , Paris 2017-09-28 - 2017-09-29
2016
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Vitenskapelig foredragJohnsen, Ingvild Bjellmo; Hansen, Marianne Dore; Stiberg, Kim Andre Ha; Tatyana, Sherstova; Mildenberger, Jennifer; Grøvdal, Lene Melsæther. (2016) The innate immune kinase TBK1 controls ULK1 and autophagy induction in response to paramyxovirus infection. CEMIR CEMIR Conference on molecular mechanisms of inflammation , Trondheim 2016-05-30 - 2016-06-02
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Vitenskapelig foredragHansen, Marianne Dore. (2016) Hepatitis C virus infection remodels the Golgi complex to trigger autophagy through the immunity-related GTPase M (IRGM). ANRS 16ème réunion du réseau national hépatites , Paris 2016-02-03 - 2016-02-04
2015
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Vitenskapelig foredragHansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Malmo, Jostein; Sherstova, Tatyana; Meurs, Eliane F.. (2015) Hepatitis C virus infection remodels the Golgi complex to trigger autophagy through the immunity-related GTPase M. 22nd International Symposium on Hepatitis C Virus and Related Viruses , Strasbourg 2015-10-09 - 2015-10-13
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Vitenskapelig foredragHansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Stiberg, Kim Andre Ha; Malmo, Jostein; Sherstova, Tatyana; Meurs, Eliane F.. (2015) Hepatitis C virus remodels the Golgi complex to trigger autophagy through the immunity-related GTPase M. Virology Department, Institut Pasteur Annual Virology Department meeting at Institut Pasteur , Pornichet, Bretagne 2015-11-16 - 2015-11-18
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IntervjuHansen, Marianne Dore. (2015) Interplay of single-stranded RNA viruses with autophagy. Intracellular mechanisms and functional impact. NBS Nytt. Tidsskrift for norsk biokjemiskselskap NBS Nytt. Tidsskrift for norsk biokjemiskselskap [Fagblad] 2015-09-14
2013
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PosterHansen, Marianne Dore; Johnsen, Ingvild Bjellmo; Meurs, Eliane F.; Anthonsen, Marit Walbye. (2013) The interplay between HCV proteins, autophagy and innate immune response during HCV infection. Keystone Keystone Symposia - Autophagy, Inflammation and Immunity , Montreal 2013-02-17 - 2013-02-22