Magnus Aasved Hjort
Kvinne-barnsenteret, 6 etg, Øya
Om
Jeg er utdannet cand. med. utgått fra Universitet i Tromsø i 2010. I 2012 begynte jeg som lege i spesialisering ved Barne- og ungdomsklinikken ved St. Olavs hospital. Overlege ved Barneklinikken, Avd. for kreft og blodsykdommer, St. Olavs hospital fra 2019. Hovedinteressen min er akutt lymfatisk leukemi, benign hematologi og målrettet molekylær behandling av kreft.
Jeg gjorde min PhD hos Rø/Børset-laben ved Myelomastosegruppen, IKOM 2014-2018. Her forsket jeg på betydningen av fosfatasen PRL-3 i B-cellekreftsykdommene akutt lymfatisk leukemi (ALL), Hodgkins lymfom og myelomatose. I mitt doktorgradsarbeid fant jeg at kreftcellene har høyere uttrykk av PRL-3 enn friske celler, og at PRL-3 var viktig for at kreftcellene skulle spre seg (migrere) og vokse (prolifere). Dette kan tyde på at PRL-3 kan være et nytt angrepspunkt i behandlingen av B-cellekreft.
Fra november 2018 begynte jeg som forsker i 50% med prosjektet "Behandlings-relatert død i NOPHO ALL 2008 protokollen". Dette er en studie som utgår fra Childhood Cancer Research Group ved IKOM, NTNU og NOPHO Event group. Prosjektet ledes av overlege/avdelingssjef Bendik Lund, instituttleder og overlege Torstein B. Rø og meg selv. Prosjektet er finansiert av Barnekreftforeningen.
Førsteamanuensis i barneonkologi fra 01.01.19 ved IKOM, NTNU.
Undervisning:
Pediatrisk hematologi og kreft - kurs for leger i spesialisering (nytt kurs fra 2020) - Kursleder
Uketjeneste for 4. års medisinerstudenter i Barneonkologi og hematologi
Cancer in children - forelesning stadium IID
Pediatric Hematology - forelsning/kurs stadium IID
Publikasjoner
2024
-
Das, Anirban;
Fernandez, Nicholas R.;
Levine, Adrian;
Bianchi, Vanessa;
Stengs, Lucie K.;
Chung, Jiil.
(2024)
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.
Cancer Discovery
Vitenskapelig artikkel
-
Egset, Kaja Solland;
Stubberud, Jan Egil;
Ruud, Ellen;
Hjort, Magnus Aasved;
Eilertsen, Mary-Elizabeth;
Sund, Anne Mari.
(2024)
Neurocognitive outcome and associated factors in long-term, adult survivors of childhood acute lymphoblastic leukemia, treated without cranial radiation therapy.
Journal of the International Neuropsychological Society
Vitenskapelig artikkel
-
Egset, Kaja Solland;
Weider, Siri;
Hjemdal, Odin;
Ruud, Ellen;
Hjort, Magnus Aasved;
Eilertsen, Mary-Elizabeth.
(2024)
Exploring the Discrepancy Between Subjective and Objective Measures of Executive Functions in Young Adult Survivors of Childhood Acute Lymphoblastic Leukemia.
Journal of Adolescent and Young Adult Oncology
Vitenskapelig artikkel
-
Ercan, Ayse Bahar;
Aronson, Melyssa;
Fernandez, Nicholas R;
Chang, Yuan;
Levine, Adrian;
Liu, Zhihui Amy.
(2024)
Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.
The Lancet Oncology
Vitenskapelig artikkel
2023
-
Persson, K.;
Thomsen, Thomsen Boeg;
Fyrberg, A.;
Castor, C.;
Hjort, Magnus Aasved;
Andreozzi, B..
(2023)
Preoperative word-finding difficulties in children with posterior fossa tumours: a European cross-sectional study.
Child's Nervous System
Vitenskapelig artikkel
2022
-
Grønbæk, Jonathan Kjær;
Laustsen, Aske Foldbjerg;
Toescu, Sebastian;
Pizer, Barry;
Mallucci, Conor;
Aquilina, Kristian.
(2022)
Left-handedness should not be overrated as a risk factor for postoperative speech impairment in children after posterior fossa tumour surgery: a prospective European multicentre study.
Child's Nervous System
Vitenskapelig artikkel
-
Grønbæk, Jonathan Kjær;
Toescu, S.;
Frič, Radek;
Nilsson, P.;
Castor, C.;
Mallucci, C..
(2022)
Postoperative speech impairment and cranial nerve deficits after secondary surgery of posterior fossa tumours in childhood: a prospective European multicentre study.
Child's Nervous System
Vitenskapelig artikkel
-
Stubberud, Anker;
Ipsen, Meta;
Brevik, Marie Kristine Strand;
Nag, Torbjørn;
Hjort, Magnus Aassved.
(2022)
En gutt i tidlig skolealder med smerter i foten.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Vitenskapelig artikkel
-
Egset, Kaja Solland;
Stubberud, Jan Egil;
Weider, Siri;
Ruud, Ellen;
Hjort, Magnus Aassved;
Eilertsen, Mary-Elizabeth B.
(2022)
Neurocognitive outcome in long-term, adult survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only.
Pediatric Blood & Cancer
Sammendrag/Abstract
2021
-
Egset, Kaja Solland;
Weider, Siri;
Stubberud, Jan Egil;
Hjemdal, Odin;
Ruud, Ellen;
Hjort, Magnus Aassved.
(2021)
Cognitive Rehabilitation for Neurocognitive Late Effects in Adult Survivors of Childhood Acute Lymphoblastic Leukemia: A Feasibility and Case-Series Study.
Frontiers in Psychology
Vitenskapelig artikkel
-
Abdollahi, Pegah;
Vandsemb, Esten;
Elsaadi, Samah;
Røst, Lisa Marie;
Yang, Rui;
Hjort, Magnus Aassved.
(2021)
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma.
The FASEB Journal
Vitenskapelig artikkel
-
Grønbæk, Jonathan Kjær;
Wibroe, Morten;
Toescu, Sebastian;
Frič, Radek;
Thomsen, Birthe Lykke;
Møller, Lisbeth Nørgaard.
(2021)
Postoperative speech impairment and surgical approach to posterior fossa tumours in children: a prospective European multicentre cohort study.
The Lancet Child and Adolescent Health
Vitenskapelig artikkel
2020
-
Lamens, Sverre Sigurd;
Hjort, Magnus Aassved.
(2020)
En jente med slapphet og alvorlige elektrolyttforstyrrelser.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Leserinnlegg
2018
-
Hjort, Magnus Aasved;
Hov, Håkon;
Abdollahi, Pegah;
Vandsemb, Esten;
Fagerli, Unn-Merete;
Lund, Bendik.
(2018)
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration.
Experimental Hematology & Oncology
Vitenskapelig artikkel
-
Hjort, Magnus Aassved;
Rø, Torstein Baade;
Børset, Magne;
Slørdahl, Tobias Schmidt;
Lund, Bendik.
(2018)
Phosphatase of regenerating liver-3 as a target for treatment of B cell malignancies.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Doktorgradsavhandling
2017
-
Hjort, Magnus Aassved;
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Fenstad, Mona H.;
Lund, Bendik;
Slørdahl, Tobias Schmidt.
(2017)
Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance.
OncoTarget
Vitenskapelig artikkel
2016
-
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Hjort, Magnus Aassved;
Misund, Kristine;
Holien, Toril;
Sponaas, Anne-Marit.
(2016)
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3.
Molecular Cancer Research
Vitenskapelig artikkel
Tidsskriftspublikasjoner
-
Das, Anirban;
Fernandez, Nicholas R.;
Levine, Adrian;
Bianchi, Vanessa;
Stengs, Lucie K.;
Chung, Jiil.
(2024)
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.
Cancer Discovery
Vitenskapelig artikkel
-
Egset, Kaja Solland;
Stubberud, Jan Egil;
Ruud, Ellen;
Hjort, Magnus Aasved;
Eilertsen, Mary-Elizabeth;
Sund, Anne Mari.
(2024)
Neurocognitive outcome and associated factors in long-term, adult survivors of childhood acute lymphoblastic leukemia, treated without cranial radiation therapy.
Journal of the International Neuropsychological Society
Vitenskapelig artikkel
-
Egset, Kaja Solland;
Weider, Siri;
Hjemdal, Odin;
Ruud, Ellen;
Hjort, Magnus Aasved;
Eilertsen, Mary-Elizabeth.
(2024)
Exploring the Discrepancy Between Subjective and Objective Measures of Executive Functions in Young Adult Survivors of Childhood Acute Lymphoblastic Leukemia.
Journal of Adolescent and Young Adult Oncology
Vitenskapelig artikkel
-
Ercan, Ayse Bahar;
Aronson, Melyssa;
Fernandez, Nicholas R;
Chang, Yuan;
Levine, Adrian;
Liu, Zhihui Amy.
(2024)
Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.
The Lancet Oncology
Vitenskapelig artikkel
-
Persson, K.;
Thomsen, Thomsen Boeg;
Fyrberg, A.;
Castor, C.;
Hjort, Magnus Aasved;
Andreozzi, B..
(2023)
Preoperative word-finding difficulties in children with posterior fossa tumours: a European cross-sectional study.
Child's Nervous System
Vitenskapelig artikkel
-
Grønbæk, Jonathan Kjær;
Laustsen, Aske Foldbjerg;
Toescu, Sebastian;
Pizer, Barry;
Mallucci, Conor;
Aquilina, Kristian.
(2022)
Left-handedness should not be overrated as a risk factor for postoperative speech impairment in children after posterior fossa tumour surgery: a prospective European multicentre study.
Child's Nervous System
Vitenskapelig artikkel
-
Grønbæk, Jonathan Kjær;
Toescu, S.;
Frič, Radek;
Nilsson, P.;
Castor, C.;
Mallucci, C..
(2022)
Postoperative speech impairment and cranial nerve deficits after secondary surgery of posterior fossa tumours in childhood: a prospective European multicentre study.
Child's Nervous System
Vitenskapelig artikkel
-
Stubberud, Anker;
Ipsen, Meta;
Brevik, Marie Kristine Strand;
Nag, Torbjørn;
Hjort, Magnus Aassved.
(2022)
En gutt i tidlig skolealder med smerter i foten.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Vitenskapelig artikkel
-
Egset, Kaja Solland;
Stubberud, Jan Egil;
Weider, Siri;
Ruud, Ellen;
Hjort, Magnus Aassved;
Eilertsen, Mary-Elizabeth B.
(2022)
Neurocognitive outcome in long-term, adult survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only.
Pediatric Blood & Cancer
Sammendrag/Abstract
-
Egset, Kaja Solland;
Weider, Siri;
Stubberud, Jan Egil;
Hjemdal, Odin;
Ruud, Ellen;
Hjort, Magnus Aassved.
(2021)
Cognitive Rehabilitation for Neurocognitive Late Effects in Adult Survivors of Childhood Acute Lymphoblastic Leukemia: A Feasibility and Case-Series Study.
Frontiers in Psychology
Vitenskapelig artikkel
-
Abdollahi, Pegah;
Vandsemb, Esten;
Elsaadi, Samah;
Røst, Lisa Marie;
Yang, Rui;
Hjort, Magnus Aassved.
(2021)
Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma.
The FASEB Journal
Vitenskapelig artikkel
-
Grønbæk, Jonathan Kjær;
Wibroe, Morten;
Toescu, Sebastian;
Frič, Radek;
Thomsen, Birthe Lykke;
Møller, Lisbeth Nørgaard.
(2021)
Postoperative speech impairment and surgical approach to posterior fossa tumours in children: a prospective European multicentre cohort study.
The Lancet Child and Adolescent Health
Vitenskapelig artikkel
-
Lamens, Sverre Sigurd;
Hjort, Magnus Aassved.
(2020)
En jente med slapphet og alvorlige elektrolyttforstyrrelser.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Leserinnlegg
-
Hjort, Magnus Aasved;
Hov, Håkon;
Abdollahi, Pegah;
Vandsemb, Esten;
Fagerli, Unn-Merete;
Lund, Bendik.
(2018)
Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration.
Experimental Hematology & Oncology
Vitenskapelig artikkel
-
Hjort, Magnus Aassved;
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Fenstad, Mona H.;
Lund, Bendik;
Slørdahl, Tobias Schmidt.
(2017)
Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance.
OncoTarget
Vitenskapelig artikkel
-
Abdollahi, Pegah;
Vandsemb, Esten Nymoen;
Hjort, Magnus Aassved;
Misund, Kristine;
Holien, Toril;
Sponaas, Anne-Marit.
(2016)
Src family kinases are regulated in multiple myeloma cells by phosphatase of regenerating liver-3.
Molecular Cancer Research
Vitenskapelig artikkel
Rapport
-
Hjort, Magnus Aassved;
Rø, Torstein Baade;
Børset, Magne;
Slørdahl, Tobias Schmidt;
Lund, Bendik.
(2018)
Phosphatase of regenerating liver-3 as a target for treatment of B cell malignancies.
Norges teknisk-naturvitenskapelige universitet
Norges teknisk-naturvitenskapelige universitet
Doktorgradsavhandling
Formidling
2022
-
PosterEgset, Kaja Solland; Stubberud, Jan Egil; Weider, Siri; Ruud, Ellen; Hjort, Magnus Aassved; Eilertsen, Mary-Elizabeth B. (2022) Neurocognitive outcome in long-term, adult survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only. 54th Congress of the International Society of Paediatric Oncology (SIOP 2022) , Barcelona 2022-09-27 - 2022-10-01
2018
-
PosterHjort, Magnus Aasved; Hov, Håkon; Abdollahi, Pegah; Vandsemb, Esten; Fagerli, Unn-Merete; Lund, Bendik. (2018) Phosphatase of regenerating liver -3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration. SIOP 2018 , Kyoto 2018-11-16 - 2018-11-19
2016
-
Vitenskapelig foredragHjort, Magnus Aasved; Abdollahi, Pegah; Vandsemb, Esten; Fenstad, Mona H.; Lund, Bendik; Slørdahl, Tobias Schmidt. (2016) PRL-3 dependent cell adhesion and migration in B-ALL. NOPHO Annual Meeting 2016-05-27 - 2016-05-31
-
PosterHjort, Magnus Aasved; Abdollahi, Pegah; Vandsemb, Esten; Fenstad, Mona H.; Lund, Bendik; Slørdahl, Tobias Schmidt. (2016) The phosphatase PRL-3 is expressed in primary B-ALL cells and is important for adhesion and migration. American Association for Cancer Research (AACR) Annual Meeting 2016-04-16 - 2016-04-20
2015
-
PosterAbdollahi, Pegah; Vandsemb, Esten Nymoen; Hjort, Magnus Aassved; Misund, Kristine; Rø, Torstein Baade; Slørdahl, Tobias Schmidt. (2015) PRL-3 increases survival of Multiple Myeloma cells through Src activation. 15th International Myeloma Workshop , Roma 2015-09-23 - 2015-09-25