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  1. Ansatte

Språkvelger

English

Helle Samdal

Last ned pressefoto
Last ned pressefoto
Foto:

Helle Samdal

Forsker
Institutt for klinisk og molekylær medisin

helle.samdal@ntnu.no
95181188 Laboratoriesenteret, 5.etg øst, Øya
Om Forskning Publikasjoner Formidling

Om

CV

I work as a researcher at the Department of Clinical and Molecular Medicine. 

My major research areas of interest includes generegulation in disease and how to manipulate gene expression using different editing techniques.

Here you can read more about the different projects I work on:

Lung cancer: https://www.ntnu.edu/ikom/lung-cancer

Bioinformatics and gene regulation 

Omega 3 fatty acids and CRC: https://www.ntnu.edu/ikom/crc/genelipid#/view/about

Dermatogenomics: https://www.ntnu.edu/hunt/mce/skin

Kompetanseord

  • CRISPR activation
  • CRISPR interference
  • Cell cultivation
  • Gene regulation
  • RNA interference
  • long non-coding RNA

Forskning

Gene-lipid interaction in colorectal cancer

This project aims to identify biomarkers (single nucleotide variants (SNVs)) for beneficial PUFA treatment of colorectal cancer.

Publikasjoner

  • Kronologisk
  • Etter kategori
  • Alle publikasjoner i Nasjonalt vitenarkiv (NVA)

2025

  • Yohan, Lefol; Hasle, Geir Amund; Hegre, Siv Anita; Samdal, Helle; Sætrom, Pål. (2025) Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation. Bioinformatics Advances
    Vitenskapelig artikkel

2023

  • Pettersen, Caroline Hild Hakvåg; Samdal, Helle; Sætrom, Pål; Wibe, Arne; Hermansen, Erland; Schønberg, Svanhild Margrethe Arentz. (2023) The Salmon Oil OmeGo Reduces Viability of Colorectal Cancer Cells and Potentiates the Anti-Cancer Effect of 5-FU. Marine Drugs
    Vitenskapelig artikkel

2021

  • Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines
    Vitenskapelig artikkel
  • Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports
    Vitenskapelig artikkel

2018

  • Samdal, Helle; Sandmoe, Malin Alise; Olsen, Lene Christin; Jarallah, Elaf Ali Hadi; Høiem, Therese Stork; Schønberg, Svanhild Margrethe Arentz. (2018) Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells. The FEBS Journal
    Vitenskapelig artikkel

2017

  • Pettersen, Caroline Hild; Samdal, Helle; Schønberg, Svanhild Margrethe Arentz. (2017) DHA-indusert stressrespons i humane tarmkreftceller. BestPractice Gastroenterologi
    Populærvitenskapelig artikkel

2016

  • Pettersen, Kristine; Monsen, Vivi Anita Talstad; Pettersen, Caroline Hild; Overland, Hilde Bremseth; Pettersen, Grete Klippenvåg; Samdal, Helle. (2016) DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radical Biology & Medicine
    Vitenskapelig artikkel

Tidsskriftspublikasjoner

  • Yohan, Lefol; Hasle, Geir Amund; Hegre, Siv Anita; Samdal, Helle; Sætrom, Pål. (2025) Using pseudotime derivative on single-cell RNA sequencing data to identify genes undergoing cell cycle regulation. Bioinformatics Advances
    Vitenskapelig artikkel
  • Pettersen, Caroline Hild Hakvåg; Samdal, Helle; Sætrom, Pål; Wibe, Arne; Hermansen, Erland; Schønberg, Svanhild Margrethe Arentz. (2023) The Salmon Oil OmeGo Reduces Viability of Colorectal Cancer Cells and Potentiates the Anti-Cancer Effect of 5-FU. Marine Drugs
    Vitenskapelig artikkel
  • Samdal, Helle; Olsen, Lene Christin; Grøn, Knut Sverre; Røyset, Elin Synnøve; Høiem, Therese Stork; Nervik, Ingunn. (2021) Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids. Biomedicines
    Vitenskapelig artikkel
  • Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2021) Joint changes in RNA, RNA polymerase II, and promoter activity through the cell cycle identify non-coding RNAs involved in proliferation. Scientific Reports
    Vitenskapelig artikkel
  • Samdal, Helle; Sandmoe, Malin Alise; Olsen, Lene Christin; Jarallah, Elaf Ali Hadi; Høiem, Therese Stork; Schønberg, Svanhild Margrethe Arentz. (2018) Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells. The FEBS Journal
    Vitenskapelig artikkel
  • Pettersen, Caroline Hild; Samdal, Helle; Schønberg, Svanhild Margrethe Arentz. (2017) DHA-indusert stressrespons i humane tarmkreftceller. BestPractice Gastroenterologi
    Populærvitenskapelig artikkel
  • Pettersen, Kristine; Monsen, Vivi Anita Talstad; Pettersen, Caroline Hild; Overland, Hilde Bremseth; Pettersen, Grete Klippenvåg; Samdal, Helle. (2016) DHA-induced stress response in human colon cancer cells - Focus on oxidative stress and autophagy. Free Radical Biology & Medicine
    Vitenskapelig artikkel

Formidling

2019

  • Poster
    Samdal, Helle; Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2019) Functional evaluation of long non-coding RNAs with potential roles during cell replication. Long Noncoding RNAs: From Molecular Mechanism to Functional Genetics , Whistler 2019-02-24 - 2019-02-28

2018

  • Poster
    Samdal, Helle; Olsen, Lene Christin; Jarallah, Elaf Ali Hadi; Schønberg, Svanhild Margrethe Arentz; Pettersen, Caroline Hild. (2018) Basal level of autophagy and MAP1LC3B-II as potential biomarkers for DHA-induced cytotoxicity in colorectal cancer cells. 2nd International NTNU Symposium Current and Future Clinical Biomarkers of Cancer: From diagnosis to immunotherapy – why is precision medicine so difficult? , Trondheim 2018-06-16 - 2018-06-17
  • Poster
    Hegre, Siv Anita; Klima, Antonin; Stovner, Endre Bakken; Samdal, Helle; Nørsett, Kristin Gabestad; Liabakk, Nina-Beate. (2018) Long non-coding RNAs in epigenetic inheritance. Noncoding RNAs: Form, Function, Physiology , Keystone, Colorado 2018-02-25 - 2018-03-01

2017

  • Poster
    Hegre, Siv Anita; Samdal, Helle; Klima, Antonin; Stovner, Endre Bakken; Nørsett, Kristin; Aas, Per Arne. (2017) Long non-coding RNAs in epigenetic inheritance * Won Poster prize of 250 EUR at the EMBO|EMBL Symposium. EMBO EMBL Symposium "The Non-Coding genome" , Heidelberg 2017-09-13 - 2017-09-16

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