Axel Karl Gottfrid Nyman
Om
Lege og Postdoktor ved NTNU. Forsker på Alzheimers sykdom ved K.G. Jebsens senter for Alzheimers sykdom. Jobber som lege i spesialisering på nevrologisk avdeling St Olav.
Født: 1989
Nåværende stilling: Postdoktor
Forskningsinteresser
- Eksperimentelle modeller for hjernesykdommer
- Bildeveiledet terapi ved hjernesykdommer
- Behandling av hjernesykdommer med melatonin
- Nevrodegenerasjon
- Avanserte MR-teknikker ved hjernesykdommer
Nåværende forskningsprosjekter
Avanserte MR-teknikker for oppdagelse av biomarkører ved tidlig Alzheimers sykdom
Metabolske endringer i hjernen ved forbigående global amnesi
Tidligere forskningsprosjekter
Melatoninbehandling av hypoksisk-iskjemisk hjerneskade i nyfødte rotter.
Lipidbaserte nanopartikler for levering av melatonin til hjernen
Intermitterende hyperoksi-hypoksi: Effekt på cerebral vaskularisering, hjernens utvikling og motorisk funksjon i nyfødte rotter.
MR-avbildning av stamcellebehandling av hypoksisk-iskjemisk hjerneskade i nyfødte og voksne rotter.
Utdanning
2009-16: Medisinstudent, NTNU
2011-15: Forskerlinjestudent, NTNU
2016-21: PhD-student, NTNU
Publikasjoner
2025
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Galwa-Støkkan, Aleksandra;
Vari, Ingunn Egeberg;
Saidi, Mikkel Elvebakk;
Selvaag, Martin;
Torsteinsbø, Victoria Troos;
Nyman, Axel Karl Gottfrid.
(2025)
Transitorisk global amnesi.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Vitenskapelig artikkel
2020
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Molska, Alicja;
Nyman, Axel Karl Gottfrid;
Sofias, Alexandros Marios;
Kristiansen, Kåre Andre;
Hak, Sjoerd;
Widerøe, Marius.
(2020)
In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.
European journal of pharmaceutics and biopharmaceutics
Vitenskapelig artikkel
2019
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Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Widerøe, Marius.
(2019)
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats.
PLOS ONE
Vitenskapelig artikkel
2017
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Augestad, Ingrid Lovise;
Nyman, Axel Karl Gottfrid;
Costa, Alex Ignatius;
Barnett, Susan Carol;
Sandvig, Axel;
Håberg, Asta.
(2017)
Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat.
Neurochemical Research
Vitenskapelig artikkel
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Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Vettukattil, Muhammad Riyas;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2017)
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy.
PLOS ONE
Vitenskapelig artikkel
2013
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Morken, Tora Sund;
Nyman, Axel Karl Gottfrid;
Sandvig, Ioanna;
Torp, Sverre Helge;
Skranes, Jon Sverre;
Goa, Pål Erik.
(2013)
Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry.
PLOS ONE
Vitenskapelig artikkel
2012
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Nyman, Axel Karl Gottfrid.
(2012)
In Bloom.
Visuell kunst
Tidsskriftspublikasjoner
-
Galwa-Støkkan, Aleksandra;
Vari, Ingunn Egeberg;
Saidi, Mikkel Elvebakk;
Selvaag, Martin;
Torsteinsbø, Victoria Troos;
Nyman, Axel Karl Gottfrid.
(2025)
Transitorisk global amnesi.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Vitenskapelig artikkel
-
Molska, Alicja;
Nyman, Axel Karl Gottfrid;
Sofias, Alexandros Marios;
Kristiansen, Kåre Andre;
Hak, Sjoerd;
Widerøe, Marius.
(2020)
In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.
European journal of pharmaceutics and biopharmaceutics
Vitenskapelig artikkel
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Widerøe, Marius.
(2019)
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats.
PLOS ONE
Vitenskapelig artikkel
-
Augestad, Ingrid Lovise;
Nyman, Axel Karl Gottfrid;
Costa, Alex Ignatius;
Barnett, Susan Carol;
Sandvig, Axel;
Håberg, Asta.
(2017)
Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat.
Neurochemical Research
Vitenskapelig artikkel
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Vettukattil, Muhammad Riyas;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2017)
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy.
PLOS ONE
Vitenskapelig artikkel
-
Morken, Tora Sund;
Nyman, Axel Karl Gottfrid;
Sandvig, Ioanna;
Torp, Sverre Helge;
Skranes, Jon Sverre;
Goa, Pål Erik.
(2013)
Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry.
PLOS ONE
Vitenskapelig artikkel
Kunstneriske produksjoner
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Nyman, Axel Karl Gottfrid.
(2012)
In Bloom.
Visuell kunst
Formidling
2025
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PosterBjørkkjær, Asbjørn; Li, Jin; Hjelme, Dag Roar; Goa, Pål Erik; Nyman, Axel Karl Gottfrid. (2025) GluCEST imaging for mapping neurometabolism. MR 2025 — the 18th biennial conference of the Norwegian Society for Magnetic Resonance , Bergen 26.05.2025 - 27.05.2025
2024
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PosterNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A personalized in vitro metabolic model of preclincal Alzheimer's disease. The Aging Brain Conference , Union Hotel Geiranger 12.06.2024 - 14.06.2024
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Vitenskapelig foredragNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A Personalized in vitro Metabolic Model of Preclinical Alzheimer’s Disease. 15th International Conference on Brain Energy Metabolism (ICBEM) , Grand Hotel Union in Ljubljana, Slovenia 17.09.2024 - 21.09.2024
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PosterJain, Avneesh; Rørnes, Anna Xiu; Farestveit, Anne; Grinde, Maria; Nyman, Axel Karl Gottfrid; Sitter, Beathe. (2024) Higher thalamic myo-Inositol measured at 7T using 1H-MR spectroscopy suggests novel mechanisms in chronic cluster headaches. 18th European Headache Concgress , Rotterdam 04.12.2024 - 07.12.2024
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Vitenskapelig foredragJain, Avneesh; Rørnes, Anna Xiu; Farestveit, Anne; Grinde, Maria; Nyman, Axel Karl Gottfrid; Sitter, Beathe. (2024) Higher thalamic myo-Inositol measured at 7Tesla suggests novel mechanisms in chronic cluster headaches. European Society for Magnetic Resonance in Medicine and Biology 40th Annual Scientific Meeting , Barcelona 02.10.2024 - 05.10.2024
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PosterJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2024) Development of a Translational Metabolic Platform for Brain Disorders, Exemplified by Preclinical Alzheimer's Disease. 4th Nordic Neuroscience Meeting 15.01.2024 - 17.01.2024
2023
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Vitenskapelig foredragJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2023) Investigation of Metabolism in Cerebral Organoids Derived from Patients with Preclinical Alzheimer's Disease. Frampeik 30.09.2023 - 30.09.2023
2017
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Faglig foredragMolska, Alicja; Sofias, Alexandros Marios; Nyman, Axel Karl Gottfrid; Hak, Sjoerd; Widerøe, Marius. (2017) Melatonin treatment for hypoxic-ischemic brain injury. Lipid-based nanoparticles as a platform for drug delivery. The 5th National PhD Conference in Neuroscience , Sommarøy 20.09.2017 - 22.09.2017
2015
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Vitenskapelig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) In-vivo MR metabolomics; A potential biomarker for neonatal hypoxic-ischemic brain injury?. Cerebral Palsy masterclass , NTNU, Trondheim 10.09.2015 - 10.09.2015
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Vitenskapelig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) Early prognostic metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo proton MR spectroscopy. MedIm PhD conference , Oslo 16.11.2015 - 17.11.2015
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Vitenskapelig foredragAugestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Anatomical, cellular and structural effects of neural stem cell and/or olfactory ensheathing cell grafts in a rat model of focal cerebral ischemia with reperfusion. 22nd Annual Conference of the American Society of Neural Therapy and Repair , Tampa, Florida 30.04.2015 - 02.05.2015
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PosterNyman, Axel Karl Gottfrid; Augestad, Ingrid Lovise; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Cellular, anatomical, and functional effects of neural stem cell and olfactory ensheathing cell co-grafts in a rat model of transient cerebral ischemia. Nordic Neuroscience 2015 , Trondheim 10.06.2015 - 12.06.2016
2014
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Faglig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. 13th National MR Meeting , Trondheim 14.01.2014 - 15.01.2014
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Faglig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. Perinatal asphyxia seminar , Trondheim 10.11.2014 - 10.11.2014
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Faglig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) Effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. Pediatric Academic Societies and Asian Society For Pediatric Research , Vancouver 03.05.2014 - 06.05.2014
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PosterBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: A longitudinal MR study. 9th Hershey Conference on Developmental Brain Injury , Maryland 03.06.2014 - 06.06.2014
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Faglig foredragNyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualization of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Frampeik 2014 - legestudentenes forskningskonferanse , Trondheim 24.10.2014 - 26.10.2014
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PosterNyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualisation of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Norwegian Research School in Neuroscience Annual Meeting , Stiklestad 22.09.2014 - 24.09.2014
2013
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Vitenskapelig foredragMorken, Tora Sund; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Ioanna; Torp, Sverre Helge; Skranes, Jon. (2013) Exposure of long-term intermittent hypoxia-hyperoxia in newborn rats: effects on brain development. Pediatric Academic Society 04.05.2013 - 07.05.2013
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PosterNyman, Axel Karl Gottfrid; Modo, Mike; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. The 1st National PhD Conference in Neuroscience , Stiklestad 10.09.2013 - 11.09.2013
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PosterNyman, Axel Karl Gottfrid; Modo, Michel; Sandvig, Axel; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. 5th Norwegian PhD Conference in Medical Imaging , Tromsø 02.10.2013 - 03.10.2013
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IntervjuNyman, Axel Karl Gottfrid. (2013) Hjerneslaget på Stiklestad. Adresseavisen Adresseavisen [null] 13.09.2013
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PosterBerger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. NRSN PhD Conference , Stiklestad 10.09.2013 - 11.09.2013
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Faglig foredragBerger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats:Preliminary results from a longitudinal MR study. PhD Conference in Medical Imaging , Tromsø 02.10.2013 - 03.10.2013
2012
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PosterNyman, Axel Karl Gottfrid; Widerøe, Marius; Haraldseth, Olav. (2012) Longitudinal visualization of stem cell therapy in the hypoxic-ischemic premature brain using MRI. The 4th National PhD Conference in Medical Imaging 28.11.2012 - 29.11.2012