Axel Karl Gottfrid Nyman
Om
Lege og Postdoktor ved NTNU. Forsker på Alzheimers sykdom ved K.G. Jebsens senter for Alzheimers sykdom. Jobber som lege i spesialisering på nevrologisk avdeling St Olav.
Født: 1989
Nåværende stilling: Postdoktor
Forskningsinteresser
- Eksperimentelle modeller for hjernesykdommer
- Bildeveiledet terapi ved hjernesykdommer
- Behandling av hjernesykdommer med melatonin
- Nevrodegenerasjon
- Avanserte MR-teknikker ved hjernesykdommer
Nåværende forskningsprosjekter
Avanserte MR-teknikker for oppdagelse av biomarkører ved tidlig Alzheimers sykdom
Metabolske endringer i hjernen ved forbigående global amnesi
Tidligere forskningsprosjekter
Melatoninbehandling av hypoksisk-iskjemisk hjerneskade i nyfødte rotter.
Lipidbaserte nanopartikler for levering av melatonin til hjernen
Intermitterende hyperoksi-hypoksi: Effekt på cerebral vaskularisering, hjernens utvikling og motorisk funksjon i nyfødte rotter.
MR-avbildning av stamcellebehandling av hypoksisk-iskjemisk hjerneskade i nyfødte og voksne rotter.
Utdanning
2009-16: Medisinstudent, NTNU
2011-15: Forskerlinjestudent, NTNU
2016-21: PhD-student, NTNU
Publikasjoner
2020
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Molska, Alicja;
Nyman, Axel Karl Gottfrid;
Sofias, Alexandros Marios;
Kristiansen, Kåre Andre;
Hak, Sjoerd;
Widerøe, Marius.
(2020)
In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.
European journal of pharmaceutics and biopharmaceutics
Vitenskapelig artikkel
2019
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Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Widerøe, Marius.
(2019)
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats.
PLOS ONE
Vitenskapelig artikkel
2017
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Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Vettukattil, Muhammad Riyas;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2017)
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy.
PLOS ONE
Vitenskapelig artikkel
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Augestad, Ingrid Lovise;
Nyman, Axel Karl Gottfrid;
Costa, Alex Ignatius;
Barnett, Susan Carol;
Sandvig, Axel;
Håberg, Asta.
(2017)
Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat.
Neurochemical Research
Vitenskapelig artikkel
2013
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Morken, Tora Sund;
Nyman, Axel Karl Gottfrid;
Sandvig, Ioanna;
Torp, Sverre Helge;
Skranes, Jon Sverre;
Goa, Pål Erik.
(2013)
Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry.
PLOS ONE
Vitenskapelig artikkel
2012
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Nyman, Axel Karl Gottfrid.
(2012)
In Bloom.
Visuell kunst
Tidsskriftspublikasjoner
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Molska, Alicja;
Nyman, Axel Karl Gottfrid;
Sofias, Alexandros Marios;
Kristiansen, Kåre Andre;
Hak, Sjoerd;
Widerøe, Marius.
(2020)
In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.
European journal of pharmaceutics and biopharmaceutics
Vitenskapelig artikkel
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Widerøe, Marius.
(2019)
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats.
PLOS ONE
Vitenskapelig artikkel
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Vettukattil, Muhammad Riyas;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2017)
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy.
PLOS ONE
Vitenskapelig artikkel
-
Augestad, Ingrid Lovise;
Nyman, Axel Karl Gottfrid;
Costa, Alex Ignatius;
Barnett, Susan Carol;
Sandvig, Axel;
Håberg, Asta.
(2017)
Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat.
Neurochemical Research
Vitenskapelig artikkel
-
Morken, Tora Sund;
Nyman, Axel Karl Gottfrid;
Sandvig, Ioanna;
Torp, Sverre Helge;
Skranes, Jon Sverre;
Goa, Pål Erik.
(2013)
Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry.
PLOS ONE
Vitenskapelig artikkel
Kunstneriske produksjoner
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Nyman, Axel Karl Gottfrid.
(2012)
In Bloom.
Visuell kunst
Formidling
2025
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PosterBjørkkjær, Asbjørn; Li, Jin; Hjelme, Dag Roar; Goa, Pål Erik; Nyman, Axel Karl Gottfrid. (2025) GluCEST imaging for mapping neurometabolism. Norsk selskap for magnetisk resonans MR 2025 — the 18th biennial conference of the Norwegian Society for Magnetic Resonance , Bergen 2025-05-26 - 2025-05-27
2024
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PosterJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2024) Development of a Translational Metabolic Platform for Brain Disorders, Exemplified by Preclinical Alzheimer's Disease. 4th Nordic Neuroscience Meeting 2024-01-15 - 2024-01-17
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PosterNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A personalized in vitro metabolic model of preclincal Alzheimer's disease. Trondheim fMRI group, MiDT national research centre, St. Olav's Hospital, and Department of Neuromedicine and Movement Science, NTNU The Aging Brain Conference , Union Hotel Geiranger 2024-06-12 - 2024-06-14
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Vitenskapelig foredragNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A Personalized in vitro Metabolic Model of Preclinical Alzheimer’s Disease. ICBEM 15th International Conference on Brain Energy Metabolism (ICBEM) , Grand Hotel Union in Ljubljana, Slovenia 2024-09-17 - 2024-09-21
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Vitenskapelig foredragJain, Avneesh; Rørnes, Anna Xiu; Farestveit, Anne; Grinde, Maria; Nyman, Axel Karl Gottfrid; Sitter, Beathe. (2024) Higher thalamic myo-Inositol measured at 7Tesla suggests novel mechanisms in chronic cluster headaches. European Society for Magnetic Resonance in Medicine and Biology 40th Annual Scientific Meeting 2024-10-02 - 2024-10-05
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PosterJain, Avneesh; Rørnes, Anna Xiu; Farestveit, Anne; Grinde, Maria; Nyman, Axel Karl Gottfrid; Sitter, Beathe. (2024) Higher thalamic myo-Inositol measured at 7T using 1H-MR spectroscopy suggests novel mechanisms in chronic cluster headaches. 18th European Headache Concgress 2024-12-04 - 2024-12-07
2023
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Vitenskapelig foredragJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2023) Investigation of Metabolism in Cerebral Organoids Derived from Patients with Preclinical Alzheimer's Disease. Frampeik 2023-09-30 - 2023-09-30
2017
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Faglig foredragMolska, Alicja; Sofias, Alexandros Marios; Nyman, Axel Karl Gottfrid; Hak, Sjoerd; Widerøe, Marius. (2017) Melatonin treatment for hypoxic-ischemic brain injury. Lipid-based nanoparticles as a platform for drug delivery. NRSN The 5th National PhD Conference in Neuroscience , Sommarøy 2017-09-20 - 2017-09-22
2015
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Vitenskapelig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) Early prognostic metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo proton MR spectroscopy. Norwegian Research School in Medical Imaging MedIm PhD conference , Oslo 2015-11-16 - 2015-11-17
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Vitenskapelig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) In-vivo MR metabolomics; A potential biomarker for neonatal hypoxic-ischemic brain injury?. Torstein Vik Cerebral Palsy masterclass , NTNU, Trondheim 2015-09-10 - 2015-09-10
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Vitenskapelig foredragAugestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Anatomical, cellular and structural effects of neural stem cell and/or olfactory ensheathing cell grafts in a rat model of focal cerebral ischemia with reperfusion. ASNTR 22nd Annual Conference of the American Society of Neural Therapy and Repair , Tampa, Florida 2015-04-30 - 2015-05-02
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PosterNyman, Axel Karl Gottfrid; Augestad, Ingrid Lovise; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Cellular, anatomical, and functional effects of neural stem cell and olfactory ensheathing cell co-grafts in a rat model of transient cerebral ischemia. Scandinavian Physiological Society Nordic Neuroscience 2015 , Trondheim 2015-06-10 - 2016-06-12
2014
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Faglig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) Effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. PAS/ASAP Pediatric Academic Societies and Asian Society For Pediatric Research , Vancouver 2014-05-03 - 2014-05-06
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PosterBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: A longitudinal MR study. Johns Hopkins University School of Medicine 9th Hershey Conference on Developmental Brain Injury , Maryland 2014-06-03 - 2014-06-06
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Faglig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. Norsk Perinatalmedisinsk Forening (NPF) Perinatal asphyxia seminar , Trondheim 2014-11-10 - 2014-11-10
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Faglig foredragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. Norsk Selskap for Magnetisk Resonans (NSMR) 13th National MR Meeting , Trondheim 2014-01-14 - 2014-01-15
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Faglig foredragNyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualization of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Frampeik 2014 - legestudentenes forskningskonferanse , Trondheim 2014-10-24 - 2014-10-26
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PosterNyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualisation of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. NRSN Norwegian Research School in Neuroscience Annual Meeting , Stiklestad 2014-09-22 - 2014-09-24
2013
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IntervjuNyman, Axel Karl Gottfrid. (2013) Hjerneslaget på Stiklestad. Adresseavisen Adresseavisen [Avis] 2013-09-13
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PosterNyman, Axel Karl Gottfrid; Modo, Mike; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. NRSN The 1st National PhD Conference in Neuroscience , Stiklestad 2013-09-10 - 2013-09-11
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Vitenskapelig foredragMorken, Tora Sund; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Ioanna; Torp, Sverre Helge; Skranes, Jon. (2013) Exposure of long-term intermittent hypoxia-hyperoxia in newborn rats: effects on brain development. Pediatric Academic Society 2013-05-04 - 2013-05-07
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PosterBerger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. NRSN NRSN PhD Conference , Stiklestad 2013-09-10 - 2013-09-11
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Faglig foredragBerger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats:Preliminary results from a longitudinal MR study. MedIm PhD Conference in Medical Imaging , Tromsø 2013-10-02 - 2013-10-03
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PosterNyman, Axel Karl Gottfrid; Modo, Michel; Sandvig, Axel; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. Norwegian Research School in Medical Imaging 5th Norwegian PhD Conference in Medical Imaging , Tromsø 2013-10-02 - 2013-10-03
2012
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PosterNyman, Axel Karl Gottfrid; Widerøe, Marius; Haraldseth, Olav. (2012) Longitudinal visualization of stem cell therapy in the hypoxic-ischemic premature brain using MRI. The 4th National PhD Conference in Medical Imaging 2012-11-28 - 2012-11-29