Axel Karl Gottfrid Nyman
Om
Lege og Postdoktor ved NTNU. Forsker på Alzheimers sykdom ved K.G. Jebsens senter for Alzheimers sykdom. Jobber som lege i spesialisering på nevrologisk avdeling St Olav.
Født: 1989
Nåværende stilling: Postdoktor
Forskningsinteresser
- Eksperimentelle modeller for hjernesykdommer
- Bildeveiledet terapi ved hjernesykdommer
- Behandling av hjernesykdommer med melatonin
- Nevrodegenerasjon
- Avanserte MR-teknikker ved hjernesykdommer
Nåværende forskningsprosjekter
Avanserte MR-teknikker for oppdagelse av biomarkører ved tidlig Alzheimers sykdom
Metabolske endringer i hjernen ved forbigående global amnesi
Tidligere forskningsprosjekter
Melatoninbehandling av hypoksisk-iskjemisk hjerneskade i nyfødte rotter.
Lipidbaserte nanopartikler for levering av melatonin til hjernen
Intermitterende hyperoksi-hypoksi: Effekt på cerebral vaskularisering, hjernens utvikling og motorisk funksjon i nyfødte rotter.
MR-avbildning av stamcellebehandling av hypoksisk-iskjemisk hjerneskade i nyfødte og voksne rotter.
Utdanning
2009-16: Medisinstudent, NTNU
2011-15: Forskerlinjestudent, NTNU
2016-21: PhD-student, NTNU
Publikasjoner
2026
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Jain, Avneesh;
Rørnes, Anna Xiu;
Farestveit, Anne;
Grinde, Maria Tunset;
Nyman, Axel Karl Gottfrid;
Sitter, Beathe;
Wergeland, Tore;
Tronvik, Erling;
Genovese, Guglielmo.
(2026)
Altered hypothalamic metabolism in chronic cluster headaches patients measured with 1H-MRS at ultra-high magnetic field.
The Journal of Headache and Pain
Vitenskapelig artikkel
-
Megens, Vere Rose;
Strandhagen, Peter Wessel;
Berntsen, Erik Magnus;
Müller, Ebba Gløersen;
Laere, Koen Van;
Eikenes, Live;
Håberg, Asta Kristine;
Lium, Gunn Tove;
Biermann, Martin;
Haugarvoll, Kristoffer.
(2026)
The clinical Alzheimer's disease spectrum classified in the A/T/N framework with<sup>18</sup>F-Flutemetamol-Centiloid,<sup>18</sup>F-MK-6240-CenTauR, and<sup>18</sup>F-FDG-AD metaROI: a multicenter memory clinic observational study.
European Journal of Nuclear Medicine and Molecular Imaging
Vitenskapelig artikkel
2025
-
Galwa-Støkkan, Aleksandra;
Vari, Ingunn Egeberg;
Saidi, Mikkel Elvebakk;
Selvaag, Martin;
Torsteinsbø, Victoria Troos;
Nyman, Axel Karl Gottfrid;
Navarro Schröder, Tobias;
Doan, Thanh Pierre.
(2025)
Transitorisk global amnesi.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Vitenskapelig artikkel
2020
-
Molska, Alicja;
Nyman, Axel Karl Gottfrid;
Sofias, Alexandros Marios;
Kristiansen, Kåre Andre;
Hak, Sjoerd;
Widerøe, Marius.
(2020)
In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.
European journal of pharmaceutics and biopharmaceutics
Vitenskapelig artikkel
2019
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Widerøe, Marius.
(2019)
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats.
PLOS ONE
Vitenskapelig artikkel
2017
-
Augestad, Ingrid Lovise;
Nyman, Axel Karl Gottfrid;
Costa, Alex Ignatius;
Barnett, Susan Carol;
Sandvig, Axel;
Håberg, Asta;
Sandvig, Ioanna.
(2017)
Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat.
Neurochemical Research
Vitenskapelig artikkel
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Vettukattil, Muhammad Riyas;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2017)
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy.
PLOS ONE
Vitenskapelig artikkel
2013
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Morken, Tora Sund;
Nyman, Axel Karl Gottfrid;
Sandvig, Ioanna;
Torp, Sverre Helge;
Skranes, Jon Sverre;
Goa, Pål Erik;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2013)
Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry.
PLOS ONE
Vitenskapelig artikkel
2012
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Nyman, Axel Karl Gottfrid.
(2012)
In Bloom.
Visuell kunst
Tidsskriftspublikasjoner
-
Jain, Avneesh;
Rørnes, Anna Xiu;
Farestveit, Anne;
Grinde, Maria Tunset;
Nyman, Axel Karl Gottfrid;
Sitter, Beathe;
Wergeland, Tore;
Tronvik, Erling;
Genovese, Guglielmo.
(2026)
Altered hypothalamic metabolism in chronic cluster headaches patients measured with 1H-MRS at ultra-high magnetic field.
The Journal of Headache and Pain
Vitenskapelig artikkel
-
Megens, Vere Rose;
Strandhagen, Peter Wessel;
Berntsen, Erik Magnus;
Müller, Ebba Gløersen;
Laere, Koen Van;
Eikenes, Live;
Håberg, Asta Kristine;
Lium, Gunn Tove;
Biermann, Martin;
Haugarvoll, Kristoffer.
(2026)
The clinical Alzheimer's disease spectrum classified in the A/T/N framework with<sup>18</sup>F-Flutemetamol-Centiloid,<sup>18</sup>F-MK-6240-CenTauR, and<sup>18</sup>F-FDG-AD metaROI: a multicenter memory clinic observational study.
European Journal of Nuclear Medicine and Molecular Imaging
Vitenskapelig artikkel
-
Galwa-Støkkan, Aleksandra;
Vari, Ingunn Egeberg;
Saidi, Mikkel Elvebakk;
Selvaag, Martin;
Torsteinsbø, Victoria Troos;
Nyman, Axel Karl Gottfrid;
Navarro Schröder, Tobias;
Doan, Thanh Pierre.
(2025)
Transitorisk global amnesi.
Tidsskrift for Den norske legeforening (Tidsskriftet)
Vitenskapelig artikkel
-
Augestad, Ingrid Lovise;
Nyman, Axel Karl Gottfrid;
Costa, Alex Ignatius;
Barnett, Susan Carol;
Sandvig, Axel;
Håberg, Asta;
Sandvig, Ioanna.
(2017)
Effects of neural stem cell and olfactory ensheathing cell co-transplants on tissue remodelling after transient focal cerebral ischemia in the adult rat.
Neurochemical Research
Vitenskapelig artikkel
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Vettukattil, Muhammad Riyas;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2017)
Early metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo 1H MR spectroscopy.
PLOS ONE
Vitenskapelig artikkel
-
Morken, Tora Sund;
Nyman, Axel Karl Gottfrid;
Sandvig, Ioanna;
Torp, Sverre Helge;
Skranes, Jon Sverre;
Goa, Pål Erik;
Brubakk, Ann-Mari;
Widerøe, Marius.
(2013)
Brain Development after Neonatal Intermittent Hyperoxia-Hypoxia in the Rat Studied by Longitudinal MRI and Immunohistochemistry.
PLOS ONE
Vitenskapelig artikkel
-
Molska, Alicja;
Nyman, Axel Karl Gottfrid;
Sofias, Alexandros Marios;
Kristiansen, Kåre Andre;
Hak, Sjoerd;
Widerøe, Marius.
(2020)
In vitro and in vivo evaluation of organic solvent-free injectable melatonin nanoformulations.
European journal of pharmaceutics and biopharmaceutics
Vitenskapelig artikkel
-
Berger, Hester Rijkje;
Nyman, Axel Karl Gottfrid;
Morken, Tora Sund;
Widerøe, Marius.
(2019)
Transient effect of melatonin treatment after neonatal hypoxic-ischemic brain injury in rats.
PLOS ONE
Vitenskapelig artikkel
Kunstneriske produksjoner
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Nyman, Axel Karl Gottfrid.
(2012)
In Bloom.
Visuell kunst
Formidling
2025
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KonferanseposterBjørkkjær, Asbjørn; Li, Jin; Hjelme, Dag Roar; Goa, Pål Erik; Nyman, Axel Karl Gottfrid. (2025) GluCEST imaging for mapping neurometabolism. MR 2025 — the 18th biennial conference of the Norwegian Society for Magnetic Resonance
2024
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KonferanseposterNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A personalized in vitro metabolic model of preclincal Alzheimer's disease. The Aging Brain Conference
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KonferanseforedragNyman, Axel Karl Gottfrid; Johannessen, Fredrik Røkke; Andreassen, Trygve; Bonnevie, Tora; Genovese, Guglielmo; Scheffler, Katja. (2024) A Personalized in vitro Metabolic Model of Preclinical Alzheimer’s Disease. 15th International Conference on Brain Energy Metabolism (ICBEM)
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KonferanseposterJain, Avneesh; Rørnes, Anna Xiu; Farestveit, Anne; Grinde, Maria; Nyman, Axel Karl Gottfrid; Sitter, Beathe; Tronvik, Erling Andreas; Meisingset, Tore Wergeland; Genovese, Guglielmo. (2024) Higher thalamic myo-Inositol measured at 7T using 1H-MR spectroscopy suggests novel mechanisms in chronic cluster headaches. 18th European Headache Concgress
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KonferanseforedragJain, Avneesh; Rørnes, Anna Xiu; Farestveit, Anne; Grinde, Maria; Nyman, Axel Karl Gottfrid; Sitter, Beathe; Meisingset, Tore Wergeland; Genovese, Guglielmo. (2024) Higher thalamic myo-Inositol measured at 7Tesla suggests novel mechanisms in chronic cluster headaches. European Society for Magnetic Resonance in Medicine and Biology 40th Annual Scientific Meeting
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KonferanseposterJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2024) Development of a Translational Metabolic Platform for Brain Disorders, Exemplified by Preclinical Alzheimer's Disease. 4th Nordic Neuroscience Meeting
2023
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KonferanseforedragJohannessen, Fredrik Røkke; Andreassen, Trygve; Scheffler, Katja; Nyman, Axel Karl Gottfrid. (2023) Investigation of Metabolism in Cerebral Organoids Derived from Patients with Preclinical Alzheimer's Disease. Frampeik
2017
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ForedragMolska, Alicja; Sofias, Alexandros Marios; Nyman, Axel Karl Gottfrid; Hak, Sjoerd; Widerøe, Marius. (2017) Melatonin treatment for hypoxic-ischemic brain injury. Lipid-based nanoparticles as a platform for drug delivery. The 5th National PhD Conference in Neuroscience
2015
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KonferanseforedragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) In-vivo MR metabolomics; A potential biomarker for neonatal hypoxic-ischemic brain injury?. Cerebral Palsy masterclass
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KonferanseforedragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Vettukattil, Muhammad Riyas; Brubakk, Ann-Mari; Widerøe, Marius. (2015) Early prognostic metabolite changes after melatonin treatment in neonatal rats with hypoxic-ischemic brain injury studied by in-vivo proton MR spectroscopy. MedIm PhD conference
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KonferanseforedragAugestad, Ingrid Lovise; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Anatomical, cellular and structural effects of neural stem cell and/or olfactory ensheathing cell grafts in a rat model of focal cerebral ischemia with reperfusion. 22nd Annual Conference of the American Society of Neural Therapy and Repair
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KonferanseposterNyman, Axel Karl Gottfrid; Augestad, Ingrid Lovise; Widerøe, Marius; Sandvig, Axel; Håberg, Asta; Sandvig, Ioanna. (2015) Cellular, anatomical, and functional effects of neural stem cell and olfactory ensheathing cell co-grafts in a rat model of transient cerebral ischemia. Nordic Neuroscience 2015
2014
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ForedragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. 13th National MR Meeting
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ForedragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. Perinatal asphyxia seminar
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ForedragBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) Effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats. Pediatric Academic Societies and Asian Society For Pediatric Research
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KonferanseposterBerger, Hester Rijkje; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2014) The effects of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: A longitudinal MR study. 9th Hershey Conference on Developmental Brain Injury
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ForedragNyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualization of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Frampeik 2014 - legestudentenes forskningskonferanse
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KonferanseposterNyman, Axel Karl Gottfrid; Sandvig, Ioanna; Widerøe, Marius. (2014) In vivo visualisation of stem cell therapy in the hypoxic-ischemic neonatal brain using MRI. Norwegian Research School in Neuroscience Annual Meeting
2013
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KonferanseforedragMorken, Tora Sund; Nyman, Axel Karl Gottfrid; Widerøe, Marius; Sandvig, Ioanna; Torp, Sverre Helge; Skranes, Jon; Brubakk, Ann-Mari; Goa, Pål Erik. (2013) Exposure of long-term intermittent hypoxia-hyperoxia in newborn rats: effects on brain development. Pediatric Academic Society
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KonferanseposterNyman, Axel Karl Gottfrid; Modo, Mike; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. The 1st National PhD Conference in Neuroscience
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KonferanseposterNyman, Axel Karl Gottfrid; Modo, Michel; Sandvig, Axel; Widerøe, Marius; Haraldseth, Olav; Håberg, Asta; Sandvig, Ioanna. (2013) Co-transplantation of neural stem cells and olfactory ensheathing cells in an adult rat stroke model. 5th Norwegian PhD Conference in Medical Imaging
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Intervju
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KonferanseposterBerger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats: Preliminary results from a longitudinal MR study. NRSN PhD Conference
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ForedragBerger, Hester Rijkje; Sonnewald, Ursula; Morken, Tora Sund; Nyman, Axel Karl Gottfrid; Brubakk, Ann-Mari; Widerøe, Marius. (2013) The effect of melatonin on brain development after hypoxic-ischemic brain injury in neonatal rats:Preliminary results from a longitudinal MR study. PhD Conference in Medical Imaging
2012
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KonferanseposterNyman, Axel Karl Gottfrid; Widerøe, Marius; Haraldseth, Olav. (2012) Longitudinal visualization of stem cell therapy in the hypoxic-ischemic premature brain using MRI. The 4th National PhD Conference in Medical Imaging