Anna Mikalsen Kollstrøm
Forskning
I study the electrophysiological and molecular properties of patient-derived neurons aimed at understanding the key principles underlying optimal neural network behavior, and how this is compromised in neurodegenerative diseases. Combining methods such as extracellular recordings (micro-electrode arrays) with transcriptomics and proteomics, the overall aim is to identify the early structural alterations and functional responses to gradually progressive neurodegeneration.
Publikasjoner
2025
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Kollstrøm, Anna Mikalsen;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2025)
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons.
American Journal of Physiology - Cell Physiology
Vitenskapelig artikkel
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Kollstrøm, Anna Mikalsen;
Grønlie, Marthe Bendiksvoll;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2025)
Induced long-term potentiation improves synaptic stability and restores network function in ALS motor neurons.
bioRxiv
Vitenskapelig artikkel
2024
-
Kollstrøm, Anna Mikalsen;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2024)
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons.
bioRxiv
Vitenskapelig artikkel
Tidsskriftspublikasjoner
-
Kollstrøm, Anna Mikalsen;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2025)
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons.
American Journal of Physiology - Cell Physiology
Vitenskapelig artikkel
-
Kollstrøm, Anna Mikalsen;
Grønlie, Marthe Bendiksvoll;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2025)
Induced long-term potentiation improves synaptic stability and restores network function in ALS motor neurons.
bioRxiv
Vitenskapelig artikkel
-
Kollstrøm, Anna Mikalsen;
Christiansen, Nicholas;
Sandvig, Axel;
Sandvig, Ioanna.
(2024)
Dysregulation of synaptic transcripts underlies network abnormalities in ALS patient-derived motor neurons.
bioRxiv
Vitenskapelig artikkel
Formidling
2025
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PosterBendiksvoll Grønlie, Marthe ; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2025) Synaptic Potentiation Stabilizes Structural and Functional Network Abnormalities in ALS Motor Neurons . Federation of European Neuroscience Societies (FENS) FENS Regional Meeting 2025 , Oslo 2025-06-16 - 2025-06-19
2024
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PosterKollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neuron networks reveals structural and functional impairments. Nordic Neuroscience Meeting 2024 , Copenhagen, Denmark 2024-01-15 - 2024-01-17
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PosterKollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel; Sandvig, Ioanna. (2024) Longitudinal assessment of ALS patient-derived motor neurons reveals altered network dynamics and synaptic impairment. FENS FENS Forum 2024 , Vienna, Austria 2024-06-25 - 2024-06-29
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PosterWinter-Hjelm, Nicolai; Hanssen, Katrine Sjaastad; Fiskum, Vegard; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Sandvig, Axel. (2024) Reverse engineered neural circuit motifs as computational substrates. FENS & Lundbeck Foundation The Brain Conference - Circuits for Movement , Rungstedgaard 2024-06-16 - 2024-06-19
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PosterGrønlie, Marthe Bendiksvoll; Kollstrøm, Anna Mikalsen; Christiansen, Nicholas; Ås Røberg, Mari Susanne; Sandvig, Axel; Sandvig, Ioanna. (2024) Advanced Cellular Models of Neurodegenerative Disease: Early Alterations in Neuronal Network Activity. Norwegian Research School in Neuroscience (NRSN) National PhD Conference in Neuroscience 2024 , Jegtvolden Fjordhotell, Inderøy 2024-09-18 - 2024-09-20
2022
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PosterKollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2022) Effects of early-onset ALS pathology on neural network dynamics . FENS Forum 2022 , Paris 2022-07-09 - 2022-07-13
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PosterKollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2022) Effects of early-onset ALS pathology on neural network dynamics. NRSN NRSN National PhD Conference in Neuroscience 2022 , Stiklestad 2022-09-28 - 2022-09-30
2021
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PosterKollstrøm, Anna Mikalsen; Sandvig, Ioanna; Sandvig, Axel. (2021) Decoding motor neuron vulnerability and connectivity in ALS. NRSN NRSN National Neuroscience Symposium 2021-06-29 - 2021-07-01