2023

• Lentini, Germana; Famà, Agata; De Gaetano, Giuseppe Valerio; Coppolino, Francesco; Mahjoub, Ahlem Khachroub; Ryan, Liv. (2023) Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation. Cell Reports Medicine
  Vitenskapelig artikkel
• Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Høiland, Ina Isabella; Ludviksen, Judith K; Lau, Corinna. (2023) Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model. Pediatric Research
  Vitenskapelig artikkel
• Nilsen, Kaja Elisabeth; Zhang, Boyao; Skjesol, Astrid; Ryan, Liv; Vagle, Hilde; Bøe, Maren Helene. (2023) Peptide derived from SLAMF1 prevents TLR4-mediated inflammation in vitro and in vivo. Life Science Alliance (LSA)
  Vitenskapelig artikkel

2022

• Johnson, Christina; Quach, Huy Quang; Lau, Corinna; Ekholt, Karin; Espevik, Terje; Woodruff, Trent M.. (2022) Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood. Journal of Immunology
  Vitenskapelig artikkel
• Nilsen, Kaja Elisabeth; Skjesol, Astrid; Kojen, June Frengen; Espevik, Terje; Stenvik, Jørgen; Yurchenko, Mariya. (2022) TIRAP/Mal Positively Regulates TLR8‐Mediated Signaling via IRF5 in Human Cells. Biomedicines
  Vitenskapelig artikkel
• Pinto, Sneha M.; Subbannayya, Yashwanth; Kim, Hera; Hagen, Lars; Górna, Maria W; Nieminen, Anni I.. (2022) Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells. iScience
  Vitenskapelig artikkel

2021

• Kim, Hera; Subbannayya, Yashwanth; Humphries, Fiachra; Skjesol, Astrid; Pinto, Sneha M.; Giambelluca, Miriam. (2021) UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis. PLOS ONE
  Vitenskapelig artikkel
• Trifonov, Lena; Yurchenko, Mariya; Skjesol, Astrid; Cohen, Guy; Espevik, Terje; Korshin, Edward E.. (2021) Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator. Molecular diversity
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Rahman, Jubayer; Kunz, Natalie; West, Erin; Freiwald, Tilo; Desai, Jigar V.. (2021) Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation . Science immunology
  Vitenskapelig artikkel
• Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.. (2021) Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia
  Vitenskapelig artikkel

2020

• Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine
  Vitenskapelig artikkel
• Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi. (2020) TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology
  Vitenskapelig artikkel

2019

• Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Retterstøl, Kjetil; Henriksen, Tore; Bollerslev, Jens. (2019) Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children. Molecular Nutrition & Food Research
  Vitenskapelig artikkel
• Pilely, Katrine; Bakke, Siril Skaret; Palarasah, Yaseelan; Skjoedt, Mikkel-Ole; Bartels, Emil D.; Espevik, Terje. (2019) Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis. Atherosclerosis
  Vitenskapelig artikkel
• Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid. (2019) Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology
  Vitenskapelig artikkel
• Moen, Siv Helen; Ehrnstrøm, Birgitta; Kojen, June Frengen; Yurchenko, Mariya; Beckwith, Kai Sandvold; Afset, Jan Egil. (2019) Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling. Frontiers in Immunology
  Vitenskapelig artikkel
• Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther. (2019) The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathogens
  Vitenskapelig artikkel
• Skjeflo, Espen Waage; Christiansen, Dorte; Landsem, Anne; Stenvik, Jørgen; Woodruff, T. M.; Espevik, Terje. (2019) Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology
  Vitenskapelig artikkel
• Bösl, Korbinian; Kandasamy, Richard Kumaran; Espevik, Terje. (2019) Novel insights on human–virus interactions through genome–wide approaches. Norwegian University of Science and Technology
  Doktorgradsavhandling
• Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje. (2019) Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood. Journal of Immunology
  Vitenskapelig artikkel
• Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi. (2019) Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis
  Vitenskapelig artikkel
• Narverud, Ingunn; Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål. (2019) Profiling of immune-related gene expression in children with familial hypercholesterolaemia. Journal of Internal Medicine
  Vitenskapelig artikkel
• Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K. (2019) NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies. mAbs
  Vitenskapelig artikkel

2018

• Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar. (2018) Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology
  Vitenskapelig artikkel
• Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin. (2018) IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology
  Vitenskapelig artikkel
• Nejati Moharrami, Neda; Boyartchuk, Victor; Espevik, Terje. (2018) Role of CD5L in control of human innate immune function. Doktoravhandlinger ved NTNU (395)
  Doktorgradsavhandling
• Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen. (2018) Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4. Clinical and Experimental Immunology
  Vitenskapelig artikkel
• Skjeflo, Espen Waage; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Woodruff, Trent M.; Espevik, Terje. (2018) Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis
  Vitenskapelig artikkel
• Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug. (2018) Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology
  Vitenskapelig artikkel
• Bösl, Korbinian; Giambelluca, Miriam; Haug, Markus; Bugge, Marit; Espevik, Terje; Kandasamy, Richard Kumaran. (2018) Coactivation of TLR2 and TLR8 in primary human monocytes triggers a distinct inflammatory signaling response. Frontiers in Physiology
  Vitenskapelig artikkel
• Christ, Anette; Günther, Patrick; Lauterbach, Mario A.R.; Duewell, Peter; Biswas, Debjani; Pelka, Karin. (2018) Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell
  Vitenskapelig artikkel
• Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology
  Vitenskapelig artikkel
• Nejati Moharrami, Neda; Tande, Erlend Bjørkøy; Ryan, Liv; Espevik, Terje; Boyartchuk, Victor. (2018) RORα controls inflammatory state of human macrophages. PLOS ONE
  Vitenskapelig artikkel

2017

• Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje; Mollnes, Tom Eirik. (2017) Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets. Journal of Leukocyte Biology
  Vitenskapelig oversiktsartikkel/review
• Bugge, Marit; Bergstrøm, Bjarte; Eide, Oda K.; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen. (2017) Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Selective Cytokine Production and Promotes Invasiveness. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Ehrnstrøm, Birgitta; Beckwith, Kai Sandvold; Yurchenko, Mariya; Moen, Siv Helen; Kojen, June Frengen; Lentini, Germana. (2017) Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages. Frontiers in Immunology
  Vitenskapelig artikkel
• Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert. (2017) Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care
  Vitenskapelig artikkel
• Espevik, Terje. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
  Vitenskapelig artikkel
• Stavik, Benedicte; Holm, Sverre; Espada Serrano, Sandra; Iversen, Nina; Sporsheim, Bjørnar; Bjerkeli, Vigdis. (2017) Increased expression of TFPI in human carotid stenosis. Thrombosis Research
  Vitenskapelig artikkel
• Espada Serrano, Sandra; Stavik, Benedicte; Holm, Sverre; Sagen, Ellen Lund; Bjerkeli, Vigdis; Skjelland, Mona. (2017) Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages. Biochemical and Biophysical Research Communications - BBRC
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Halvorsen, Bente; Sporsheim, Bjørnar; Garred, Peter; Aukrust, Pål; Mollnes, Tom Eirik. (2017) Complement activation by cholesterol crystals triggers a subsequent cytokine response. Molecular Immunology
  Vitenskapelig artikkel
• Gregersen, Ida; Sandanger, Øystein; Askevold, Erik Tandberg; Sagen, Ellen Lund; Yang, Kuan; Holm, Sverre. (2017) Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation. PLOS ONE
  Vitenskapelig artikkel
• Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology
  Vitenskapelig artikkel
• Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia
  Vitenskapelig artikkel
• Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Inass, Elyouncha; Sporsheim, Bjørnar; Gregersen, Ida. (2017) Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis. Atherosclerosis
  Vitenskapelig artikkel
• Stavik, Benedicte; Espada, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Sandset, Per Morten; Dahl, Tuva Børresdatter. (2017) TFPI in human atherosclerotic plaques. Research and Practice in Thrombosis and Haemostasis (RPTH)
  Sammendrag/abstract

2016

• Varghese, Paramel G; Folkersen, Lasse; Strawbridge, Rona J.; Halvorsen, Bente; Yndestad, Arne; Ranheim, Trine. (2016) NLRP3 inflammasome expression and activation in human atherosclerosis. Journal of the American Heart Association (JAHA)
  Vitenskapelig artikkel
• Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars. (2016) Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation. Journal of Controlled Release
  Vitenskapelig artikkel
• Sherstova, Tatyana; Stokke, Bjørn Torger; Anthonsen, Marit Walbye; Espevik, Terje. (2016) Quantitative atomic force microscopy and light microscopy of hydrogels and cells. Norwegian University of Science and Technology
  Doktorgradsavhandling
• Bugge, Marit; Nilsen, Nadra J.; Espevik, Terje. (2016) Toll-Like Receptor 3 Signaling in Intestinal Epithelial Cells. Norwegian University of Science and Technology
  Doktorgradsavhandling
• Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo. (2016) Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis. PLOS ONE
  Vitenskapelig artikkel
• Zimmer, Sebastian; Grebe, Alena; Bakke, Siril Skaret; Bode, Niklas; Halvorsen, Bente; Ulas, Thomas. (2016) Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Science Translational Medicine
  Vitenskapelig artikkel
• Nymo, Stig Haugset; Gustavsen, Alice; Nilsson, Per; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik. (2016) Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. Journal of Immunology
  Vitenskapelig artikkel
• Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases
  Vitenskapelig artikkel
• Kleveland, Ola; Kunszt, Gabor; Bratlie, Marte; Ueland, Thor; Broch, Kaspar; Holte, Espen. (2016) Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial. European Heart Journal
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik. (2016) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Immunobiology
  Sammendrag/abstract
• Pilely, Katrine; Rosbjerg, Anne; Genster, Ninette; Gál, Peter; Pál, Gábor; Halvorsen, Bente. (2016) Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis. Journal of Immunology
  Vitenskapelig artikkel

2015

• Skjeflo, Espen Waage; Sagatun, Caroline; Dybwik, Knut; Aam, Sturla; Urving, Sven Haakon; Nunn, Miles A.. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Critical Care
  Vitenskapelig artikkel
• Espevik, Terje. (2015) Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation. Journal of Immunology
  Vitenskapelig artikkel
• Nilsen, Nadra; Gregory I., Vladimer; Stenvik, Jørgen; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit. (2015) A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Lau, Corinna; Olstad, Ole Kristoffer; Holden, Marit; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore. (2015) Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data
  Vitenskapelig artikkel
• Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology
  Vitenskapelig artikkel
• Klein, Dionne; Skjesol, Astrid; Kers-Rebel, Esther D.; Sherstova, Tatyana; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo. (2015) CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation. Traffic: The moving front of cell biology
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology
  Vitenskapelig artikkel
• Egge, Kjetil Hagene; Barratt-Due, Andreas; Nymo, Stig Haugset; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lau, Corinna. (2015) The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load. Clinical and Experimental Immunology
  Vitenskapelig artikkel
• Lau, Corinna; Nygård, Ståle; Fure, Hilde; Olstad, Ole Kristoffer; Holden, Marit; Lappegård, Knut Tore. (2015) CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLOS ONE
  Vitenskapelig artikkel
• Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore. (2015) The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis. Atherosclerosis
  Vitenskapelig oversiktsartikkel/review
• Sponaas, Anne-Marit; Moen, Siv Helen; Liabakk, Nina-Beate; Feyzi, Emadoldin; Holien, Toril; Kvam, Solveig. (2015) The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma. Immunity,Inflammation and Disease
  Vitenskapelig artikkel

2014

• Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje; Mollnes, Tom Eirik. (2014) Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology
  Vitenskapelig artikkel
• Nordgård, Catherine Taylor; Nonstad, Unni; Olderøy, Magnus Østgård; Espevik, Terje; Draget, Kurt Ingar. (2014) Alterations in mucus barrier function and matrix structure induced by guluronate oligomers. Biomacromolecules
  Vitenskapelig artikkel
• Skjeflo, Espen Waage; Christiansen, Dorte; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2014) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by staphylococcus aureus in a human whole blood model. Journal of Immunology
  Vitenskapelig artikkel
• Huber-Lang, Markus; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nilsson, Per; Nunn, Miles A.. (2014) Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. Journal of Immunology
  Vitenskapelig artikkel
• Franklin, Bernardo S; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M; Stutz, Andrea; Engels, Gudrun. (2014) The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology
  Vitenskapelig artikkel
• Lappegård, Knut Tore; Garred, Peter; Jonasson, Lena; Espevik, Terje; Aukrust, Pål; Yndestad, Arne. (2014) A vital role for complement in heart disease. Molecular Immunology
  Vitenskapelig oversiktsartikkel/review
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik. (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases
  Vitenskapelig artikkel
• Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret. (2014) Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology
  Vitenskapelig artikkel
• Arlov, Øystein; Aachmann, Finn Lillelund; Sundan, Anders; Espevik, Terje; Skjåk-Bræk, Gudmund. (2014) Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees. Biomacromolecules
  Vitenskapelig artikkel

2013

• Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Inger; Nilsson, Per; Lambris, J. (2013) Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis. Molecular Immunology
  Sammendrag/abstract
• Espevik, Terje. (2013) Sensorer som setter i gang betennelse: hvordan virker de og hvorfor trenger vi dem?. Årbok / Det norske videnskaps-akademi
  Populærvitenskapelig artikkel
• Espevik, Terje. (2013) CEMIR's research topic is inflammation.
  Nettsider (opplysningsmateriale)
• Rokstad, Anne Mari; Strand, Berit Løkensgard; Espevik, Terje; Mollnes, Tom Eirik. (2013) Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model. Micro and Nanosystems
  Vitenskapelig artikkel
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv. (2013) The medicinal mushroom Agaricus blazei Murill promotes NF-B activation via stimulation of TLR2 and inhibits its activation via TLR4. Journal of Pharmaceutical and Biomedical Sciences
  Vitenskapelig artikkel
• Espevik, Terje. (2013) CEMIR sitt forskningstema er inflammasjon.
  Nettsider (opplysningsmateriale)
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials
  Vitenskapelig artikkel
• Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv. (2013) Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology
  Sammendrag/abstract
• Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars. (2013) Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology
  Sammendrag/abstract
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology
  Vitenskapelig artikkel
• Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Andersen, Jan Terje; Berntzen, Gøril; Pharo, Anne Margrethe. (2013) Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation. Journal of Immunology
  Vitenskapelig artikkel
• Østvik, Ann Elisabet; Granlund, Atle; Bugge, Marit; Nilsen, Nadra; Torp, Sverre Helge; Waldum, Helge. (2013) Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation. Inflammatory Bowel Diseases
  Vitenskapelig artikkel
• Sandanger, Øystein; Ranheim, Trine; Vinge, Leif Erik; Bliksøen, Marte; Alfsnes, Katrine; Finsen, Alexandra. (2013) The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovascular Research (CVR)
  Vitenskapelig artikkel
• Grimstad, Øystein; Husebye, Harald; Espevik, Terje. (2013) TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner. Journal of dermatological science (Amsterdam)
  Vitenskapelig artikkel
• Granlund, Atle Van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, Ignat; Gustafsson, Björn; Kidd, Mark. (2013) Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis. PLOS ONE
  Vitenskapelig artikkel

2012

• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje. (2012) Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease. Inflammatory Bowel Diseases
  Sammendrag/abstract
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology
  Sammendrag/abstract
• Stenvik, Jørgen; Sletta, Håvard; Grimstad, Øystein; Pukstad, Brita; Ryan, Liv; Aune, Randi. (2012) Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium. Journal of Biomedical Materials Research. Part A
  Vitenskapelig artikkel
• Christiansen, Dorte; Stenvik, Jørgen; Brekke, Ole Lars; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time. Immunobiology
  Sammendrag/abstract
• Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nunn, Miles A.; Espevik, Terje. (2012) The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14. Immunobiology
  Sammendrag/abstract
• Christiansen, Dorte; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood. Advances in Experimental Medicine and Biology
  Vitenskapelig artikkel
• Klein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2012) Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein. Journal of Molecular Recognition
  Vitenskapelig artikkel
• Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science
  Vitenskapelig artikkel
• Doyle, SL; Husebye, Harald; Connolly, D; Espevik, Terje; O'Neill, LAJ; McGettrick, AF. (2012) The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nature Communications
  Vitenskapelig artikkel
• Skjeflo, Espen; Christiansen, Dorte; Lambris, John D.; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2012) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model. Immunobiology
  Sammendrag/abstract
• Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv. (2012) Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology
  Sammendrag/abstract
• Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2012) Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes. Experimental Dermatology
  Vitenskapelig artikkel
• Granlund, Atle; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, I; Gustafsson, Björn; Kidd, M. (2012) Dissecting the IBD Transcriptome. Inflammatory Bowel Diseases
  Sammendrag/abstract
• Barratt-Due, Andreas; Pischke, Søren Erik; Brekke, Ole Lars; Thorgersen, Ebbe Billmann; Nielsen, Erik Waage; Espevik, Terje. (2012) Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation. Immunobiology
  Vitenskapelig oversiktsartikkel/review
• Østvik, Ann Elisabet; Nilsen, Nadra; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge. (2012) Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation. Journal of Crohn’s and Coltis Supplements
  Sammendrag/abstract
• Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Damås, Jan Kristian; Wright, Samuel. (2012) Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP). Immunobiology
  Sammendrag/abstract
• Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Berntzen, Gøril; Stokes, Christopher R.; Espevik, Terje. (2012) Recombinant anti-human and anti-porcine CD14 antibodies. Immunobiology
  Sammendrag/abstract

2011

• Grimstad, Øystein; Sandanger, Øystein; Ryan, Liv; Otterdal, Kari; Damås, Jan Kristian; Pukstad, Brita. (2011) Cellular sources and inducers of cytokines present in acute wound fluid. Wound Repair and Regeneration
  Vitenskapelig artikkel
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia
  Vitenskapelig artikkel
• Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Pedersen, Anne-Mari Gjestvang; Husebye, Harald; Espevik, Terje; Sandvig, Kirsten. (2011) Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunology and Medical Microbiology
  Vitenskapelig artikkel
• Nørgaard, Nikolai Nordberg; Holien, Toril; Jönsson, S; Hella, Hanne; Espevik, Terje; Sundan, Anders. (2011) CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis. Bone
  Sammendrag/abstract

2010

• Salvesen, Bodil; Stenvik, Jørgen; Rosetti, Carlo; Saugstad, Ola D; Espevik, Terje; Mollnes, Tom E.. (2010) Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner. Molecular Immunology
  Vitenskapelig artikkel
• Etokebe, GE; Skjeldal, F; Nilsen, Nadra; Rodionov, Dmitrii; Knezevic, Jelena; Bulat-Kardum, Ljiljana. (2010) Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele. Scandinavian Journal of Immunology
  Vitenskapelig artikkel
• Duewell, P; Kono, H; Rayner, KJ; Sirois, CM; Vladimer, G; Bauernfeind, FG. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature
  Vitenskapelig artikkel
• Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases
  Vitenskapelig artikkel
• Nørgaard, Nikolai Nordberg; Holien, Toril; Jonsson, Sofia; Hella, Hanne; Espevik, Terje; Sundan, Anders. (2010) CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis. Journal of Immunology
  Vitenskapelig artikkel
• Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam)
  Vitenskapelig artikkel
• Nilsen, Asbjørn Magne; Vik, Randi; Behrens, Carl; Drabløs, Per Arne; Espevik, Terje. (2010) Beryllium Sensitivity Among Workers at a Norwegian Aluminum Smelter. American Journal of Industrial Medicine
  Vitenskapelig artikkel
• Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2010) Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy. Ultramicroscopy
  Vitenskapelig artikkel
• Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2010) TLR3 mediated cytotoxicity in keratinocytes is inhibited by co-stimulation with oligodeoxynucleotides. Journal of Investigative Dermatology
  Sammendrag/abstract
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines. Blood
  Sammendrag/abstract
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil. (2010) The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro. European Journal of Cancer
  Sammendrag/abstract
• Christiansen, D; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, JD; Espevik, Terje; Mollnes, Tom Eirik. (2010) Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood. Molecular Immunology
  Sammendrag/abstract
• Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow; Halaas, Øyvind. (2010) The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity
  Vitenskapelig artikkel

2009

• Espevik, Terje; Rokstad, Anne Mari; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund. (2009) Mechanisms of the host immune response to alginate microcapsules.
  Faglig kapittel
• Palsson-McDermott, EM; Doyle, SL; McGettrick, AF; Hardy, M; Husebye, Harald; Banahan, K. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nature Immunology
  Vitenskapelig artikkel
• Sandanger, Øystein; Sandanger, O; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, Ann-Charlotte; Iversen, AC. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology
  Vitenskapelig artikkel
• Yndestad, A; Landrø, Linn; Ueland, Thor; Dahl, CP; Flo, Trude Helen; Vinge, Leif Erik. (2009) Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. European Heart Journal
  Vitenskapelig artikkel
• Castellheim, A; Brekke, Ole Lars; Espevik, T; Harboe, M; Harboe, M; Mollnes, Tom Eirik. (2009) Innate Immune Responses to Danger Signals in Systemic Inflammatory Response Syndrome and Sepsis. Scandinavian Journal of Immunology
  Vitenskapelig oversiktsartikkel/review
• Damås, Jan Kristian; Davi, Giovanni; Jensenius, M; Santilli, F; Otterdal, K; Ueland, T. (2009) Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever. Journal of Infection
  Vitenskapelig artikkel
• Iversen, Ann-Charlotte; Steinkjer, Bjørg; Nilsen, Nadra; Bohnhorst, Janne Øvrebø; Moen, Siv Helen; Vik, Randi. (2009) A proviral role for CpG in cytomegalovirus infection. Journal of Immunology
  Vitenskapelig artikkel
• Standal, Therese; Norgaard, NN; Bohnhorst, J; Espevik, T; Waage, A; Sundan, A. (2009) Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?. Clinical Lymphoma & Myeloma
  Sammendrag/abstract

2008

• Nilsen, Nadra; Espevik, Terje; Lien, Egil. (2008) Toll-like receptor 2 expression, regulation and signaling. Tapir Akademisk Forlag Tapir Akademisk Forlag
  Doktorgradsavhandling
• Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Effects of CpG-DNA on Toll-like receptor 9 studied by AFM. TRAUNER Verlag TRAUNER Verlag
  Vitenskapelig antologi/Konferanseserie
• Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Espevik, Terje. (2008) Intracellular Trafficing of Toll-like Receptors. CRC Press
  Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
• Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, John D.; Mollnes, Tom Eirik; Brandtzaeg, P. (2008) Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity
  Vitenskapelig artikkel
• Mollnes, Tom Eirik; Christiansen, D; Brekke, Ole Lars; Espevik, T. (2008) Hypothesis: Combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response. Advances in Experimental Medicine and Biology
  Vitenskapelig artikkel
• Landrø, Linn Aina Ysland; Landro, L; Damås, Jan Kristian; Damas, JK; Flo, Trude Helen; Heggelund, L. (2008) Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy. Clinical and Experimental Immunology
  Vitenskapelig artikkel
• Hetland, G; Tryggestad, AMA; Forland, T; Johnson, E; Ryan, L; Espevik, Terje. (2008) Proposed immunomodulatory co-therapy for hematological cancer by the medicinal mushroom Agaricus blazei Murill, is facilitated by its stimulation of TLR2 and activation of NF-KB. Vox Sanguinis
  Sammendrag/abstract
• Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, JD; Mollnes, TE; Brandtzæg, Petter. (2008) Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity
  Vitenskapelig artikkel
• Nilsen, Nadra; Deininger, S; Nonstad, Unni; Skjeldal, F; Husebye, Harald; Rodionov, D. (2008) Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36. Journal of Leukocyte Biology
  Vitenskapelig artikkel

2007

• Tunheim, G; Thompson, KM; Fredriksen, AB; Espevik, Terje; Schjetne, KW; Bogen, B. (2007) Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates. Vaccine
  Vitenskapelig artikkel
• Latz, E; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, CM; Klein, Dionne. (2007) Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9. International Immunology
  Vitenskapelig artikkel
• Halaas, Øyvind; Husebye, Harald; Espevik, Terje. (2007) The journey of Toll-like receptors in the cell. Advances in Experimental Medicine and Biology
  Vitenskapelig artikkel
• Latz, Eicke; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, Cherilyn m.; Klein, Dionne. (2007) Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nature Immunology
  Vitenskapelig artikkel

2006

• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 3. Mars 2006. Norges Teknisk-Naturvitenskapelige Universitet
  Rapport
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 4. April 2006. Norges Teknisk-Naturvitenskapelige Universitet
  Rapport
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing at Hydro Aluminium Karmøy AS. Final Report. June 2006. Norwegian University of Science and Technology
  Rapport
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) BeLPT testing Karmøy. Undervegsrapport 1. Januar 2006. Norges Teknisk-Naturvitenskapelige Universitet
  Rapport
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 2. Februar 2006. Norges Teknisk-Naturvitenskapelige Universitet
  Rapport
• Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massimiliano; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje. (2006) Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials
  Vitenskapelig artikkel
• Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO Journal
  Vitenskapelig artikkel
• Bohnhorst, Janne Øvrebø; Rasmussen, T; Moen, Siv H; Fløttum, Marianne; Knudsen, L; Børset, Magne. (2006) Toll-like receptors mediate proliferation and survival of multiple myeloma cells. Leukemia
  Vitenskapelig artikkel
• Ueland, Thor; Espevik, Terje; Kjekshus, John; Gullestad, Lars; Omland, Torbjørn; Squire, Iain B.. (2006) Mannose binding lectin and soluble Toll-lilke receptor 2 in heart failure following acute myocardial infarction. Journal of Cardiac Failure
  Vitenskapelig artikkel
• Johnsen, Ingvild Bjellmo; Nguyen, Thank Thuy Thi; Ringdal, Monika; Tryggestad, AM; Bakke, Oddmund; Lien, Egil. (2006) Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. EMBO Journal
  Vitenskapelig artikkel
• Espevik, Terje; Lien, Egil. (2006) Vaksine mot svartedauen. Gemini
  Populærvitenskapelig artikkel
• Espevik, Terje; Skjåk-Bræk, Gudmund. (2006) Friskere fisk med tang og tare. Gemini
  Populærvitenskapelig artikkel

2005

• Rokstad, Anne Mari Aukan; Bjerkvig, Rolf; Espevik, Terje; Lund-Johansen, M. (2005) Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology. Book chapter: Cell encapsulation therapy for malignant gliomas. Springer Springer
  Vitenskapelig antologi/Konferanseserie
• Heggelund, Lars; Mollnes, Tom Eirik; Espevik, Terje; Muller, Fredrik; Kristiansen, Knut Ivan; Aukrust, Pål. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection. European Journal of Clinical Investigation
  Vitenskapelig artikkel
• Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P. (2005) Modulatory effect of mannose-binding lectin on cytokine resposes: possible roles in HIV infection. European Journal of Clinical Investigation
  Vitenskapelig artikkel
• Mancuso, Guiseppe; Midiri, A; Biondo, Carmelo; Beninati, C.; Gambuzza, M; Macri, D. (2005) Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4. Infection and Immunity
  Vitenskapelig artikkel
• Manukyan, M; Triantafilou, K; Triantafilou, M; Mackie, A; Nilsen, Nadra Jesmine; Espevik, Terje. (2005) Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1. European Journal of Immunology
  Vitenskapelig artikkel
• Dybdahl, Brit; Slørdahl, Stig Arild; Waage, Anders; Kierulf, Peter; Espevik, Terje; Sundan, Anders. (2005) Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart
  Vitenskapelig artikkel
• Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: roles in HIV infection. European Journal of Clinical Investigation
  Vitenskapelig artikkel

2004

• Nilsen, Nadra; Nonstad, Unni; Kahn, Naseema; Knetter, Cathrine; Akira, Shizuo; Sundan, Anders. (2004) Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Dybdahl, Brit; Wahba, Alexander; Haaverstad, Rune; Kirkeby-Garstad, I.; Kierulf, P; Espevik, Terje. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery
  Vitenskapelig artikkel
• Liabakk, Nina-Beate; Espevik, Terje. (2004) Monoclonal antibodies against TRAIL. Vitamines and Hormones
  Vitenskapelig artikkel
• Heggelund, L; Damås, Jan Kristian; Damas, JK; Yndestad, A; Holm, AM; Muller, F. (2004) Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences. Clinical and Experimental Immunology
  Vitenskapelig artikkel
• Espevik, Terje. (2004) Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1. Journal of Immunology
  Vitenskapelig artikkel
• Latz, E; Schoenemeyer, A; Visintin, A; Fitzgerald, KA; Monks, BG; Knetter, Cathrine. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nature Immunology
  Vitenskapelig artikkel
• Latz, E; Visintin, A; Espevik, Terje; Golenbock, DT. (2004) Mechanisms of TLR9 activation. Journal of Endotoxin Research
  Vitenskapelig artikkel
• Heggelund, L; Muller, F; Lien, E; Yndestad, A; Ueland, T; Kristiansen, KI. (2004) Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication. Clinical Infectious Diseases
  Vitenskapelig artikkel
• Heggelund, L; Flo, Trude Helen; Berg, K.; Lien, E; Espevik, Terje. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
  Vitenskapelig artikkel
• Halaas, Øyvind; Liabakk, Nina-Beate; Vik, Randi; Beninati, C; Henneke, P; Sundan, Anders. (2004) Monocytes stimulated with group B Streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand. Scandinavian Journal of Immunology
  Vitenskapelig artikkel
• Nilsen, N; Nonstad, U; Khan, N; Knetter, Cathrine; Akira, S; Sundan, Anders. (2004) Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Dybdahl, Brit; Wahba, Alexander; Haaverstad, R; Kirkeby-Garstad, Idar; Kierulf, Peter; Espevik, Terje. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery
  Vitenskapelig artikkel
• Heggelund, Lars; Flo, T; Berg, K; Lien, T; Mollnes, TE; Ueland, Thor. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London)
  Vitenskapelig artikkel
• Frantisek, S; Latz, E; Re, F; Mandell, L; Repik, G; Golenbock, D. (2004) Importance of extra-and intracellular domains of TLR1 and TLR2 receptors in NF-kappa B signaling. Tissue Antigens
  Sammendrag/abstract

2003

• Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy. Biotechnology and Bioengineering
  Vitenskapelig artikkel
• Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Syvertsen, Kjersti R.; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Microcapsules made by enzymatically tailored alginate. Journal of Biomedical Materials Research
  Vitenskapelig artikkel
• Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, K.; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund. (2003) Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin. Cell Transplantation
  Vitenskapelig artikkel
• Adib-Conquy, M; Moine, P; Asehnoune, K; Edouard, A; Espevik, Terje; Miyake, K. (2003) Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. American Journal of Respiratory and Critical Care Medicine
  Vitenskapelig artikkel
• Visintin, A; Latz, Eicke; Monks, Brian G.; Espevik, Terje; Golenbock, Douglas T.. (2003) Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Sandor, F; Latz, Eicke; Mandell, L; Repik, G; Golenbock, Douglas T.; Espevik, Terje. (2003) Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling. Journal of Cell Biology
  Vitenskapelig artikkel
• Espevik, Terje; Latz, Eicke; Lien, Egil; Monks, Brian G.. (2003) Cell distribution and functions of Toll-like receptor 4 studied by fluorescent gene constructs. Scandinavian Journal of Infectious Diseases
  Vitenskapelig artikkel
• Mori, Y; Yoshimura, A; Ukai, T; Lien, Egil; Espevik, Terje; Hara, Y. (2003) Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis. Oral Microbiology and Immunology
  Vitenskapelig artikkel
• Schjetne, KW; Thompson, KM; Nilsen, Nadra; Flo, Trude Helen; Fleckenstein, B; Iversen, JG. (2003) Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. Journal of Immunology
  Vitenskapelig artikkel
• Latz, E; Visintin, A; Lien, E; Fitzgerald, KA; Espevik, Terje; Golenbock, DT. (2003) The LPS receptor generates inflammatory signals from the cell surface. Journal of Endotoxin Research
  Vitenskapelig artikkel
• Schjetne, KW; Thompson, Keith; Fleckenstein, Burkhard; Aarvak, Tanja; Flo, T. H.; Iversen, Jens Gustav. (2003) Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses. Journal of Immunology
  Vitenskapelig artikkel

2002

• Strand, Berit Løkensgard; Gåserød, Olav; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (2002) Alginate-polylysine-alginate microcapsules – effect of size reduction on capsule properties. Journal of Microencapsulation
  Vitenskapelig artikkel
• Espevik, Terje. (2002) På väg att knäcka hjärntumörer. Länstidningen, Østersund, Sverige
  Kronikk
• Dybdahl, Brit; Lien, Egil; Flo, Trude Helen; Espevik, Terje; Sundan, Anders; Wahba, Alexander. (2002) Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel. Circulation
  Vitenskapelig artikkel
• Tamai, Riyoko; Sakuta, T; Matsushita, K; Torii, M; Takeuchi, Osamu; Akira, Shizuo. (2002) Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression. Infection and Immunity
  Vitenskapelig artikkel
• Latz, Eicke; Visintin, A; Lien, Egil; Fitzgerald, KA; Monks, Brian G.; Kurt-Jones, EA. (2002) Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Belge, KU; Dayyani, F; Horelt, A; Siedlar, M; Frankenberger, M; Frankenberger, B. (2002) The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF. Journal of Immunology
  Vitenskapelig artikkel
• Dybdahl, Brit; Wahba, Alexander; Lien, Egil; Flo, Trude Helen; Waage, Anders; Sellevold, Olav F Münter. (2002) Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation
  Vitenskapelig artikkel
• Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig Sophus; Espevik, Terje. (2002) Development, characterization and use of monoclonal antibodies against sTRAIL measurement of sTRAIL by ELISA. Journal of Immunological Methods (JIM)
  Vitenskapelig artikkel
• Ellingsen, E.A.; Morath, S; Flo, Trude Helen; Schromm, Andra; Hartung, T; Thiemermann, C. (2002) Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. Medical Science Monitor
  Vitenskapelig artikkel
• van der Kleij, D; Latz, Eicke; Brouwers, JF; Kruize, YC; Schmitz, M; Kurt-Jones, EA. (2002) A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates Toll-like recepytor 2 and affects immune polarization. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation
  Vitenskapelig artikkel
• Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry
  Vitenskapelig artikkel

2001

• Jenssen, Jon A; Espevik, Terje. (2001) Cellebiologisk metode for å påvise biologisk aktivitet av svevestøv. SINTEF Rapport
  Rapport
• Iversen, Ann-Charlotte; Sundan, Anders; Espevik, Terje. (2001) IFN-alpha(2b) and IFN-beta induce TRAIL-mediated NK cell cytotoxicity. The FASEB Journal
  Sammendrag/abstract
• Wang, J; Warris, A; Ellingsen, E.A.; Jorgensen, P.F.; Flo, Trude Helen; Espevik, Terje. (2001) Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infection and Immunity
  Vitenskapelig artikkel
• Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig; Espevik, Terje. (2001) Development, characterization and use of monclonal antibodies against Strail: Measurement of Strail by Elisa. Journal of Immunological Methods (JIM)
  Vitenskapelig artikkel
• Liabakk, Nina-Beate; Waage, Anders; Lien, Egil; Stenvik, Jørgen; Espevik, Terje. (2001) Cytokine bioassays. Methods in Molecular Medicine
  Vitenskapelig artikkel
• Sugawara, Shunji; Yang, Shuhua; Iki, Koichi; Hatakeyama, Junko; Tamai, Riyoko; Takeuchi, Osamu. (2001) Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by Toll-like receptor 2. Infection and Immunity
  Vitenskapelig artikkel
• Strand, Berit Løkensgard; Ryan, Liv; Int Veld, Peter; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation
  Vitenskapelig artikkel
• Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology
  Vitenskapelig artikkel
• Lien, Egil; Chow, Jesse C.; Hawkins, Lynn D.; McGuinness, Pamela D.; Miyake, Kensuke; Espevik, Terje. (2001) A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Espevik, Terje. (2001) Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin. Annals of the New York Academy of Sciences
  Vitenskapelig artikkel
• Henneke, Philipp; Takeuchi, Osamu; van Strijp, JA; Guttormsen, HK; Smith, JA; Schromm, Andra. (2001) Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. Journal of Immunology
  Vitenskapelig artikkel
• Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
  Vitenskapelig artikkel

2000

• Espevik, Terje; Waage, Anders; Sundan, A.. (2000) Summary of the 8 th International TNF Congress. Trondheim. NBS-nytt
  Fagbok
• Espevik, Terje; Waage, Anders; Sundan, Anders. (2000) Summary of the 8th International TNF Congress, Trondheim, May 14-18, 2000. NBS-nytt
  Rapport
• Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
  Vitenskapelig artikkel
• Cuzzola, M.; Mancuso, G.; Beninati, C.; Biondo, C.; Genovese, F.; Tomasello, F.. (2000) _B2 integrins are involved in cytokine responses to whole gram-positive bacteria. Journal of Immunology
  Vitenskapelig artikkel
• Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology
  Vitenskapelig artikkel
• Skjåk-Bræk, Gudmund; Flo, Trude Helen; Halaas, Øyvind; Espevik, Terje. (2000) Immune stimulating properties of di-equatorially beta(1->4) linked poly-uronides. Proceedings of the Phytochemical Society of Europe
  Vitenskapelig artikkel
• Cuzzola, Maria; Mancuso, Guiseppe; Beninati, Concetta; Biondo, Carmelo; von Hunolstein, Christina; Orefici, Graziella. (2000) Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products. Infection and Immunity
  Vitenskapelig artikkel
• Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity
  Vitenskapelig artikkel
• Falch, Berit H.; Espevik, Terje; Ryan, Liv; Stokke, Bjørn Torger. (2000) The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation. Carbohydrate Research
  Vitenskapelig artikkel
• Lien, E.; Espevik, Terje. (2000) Toll-lignende reseptorer - kroppens sensorer for infeksjon. NBS-nytt
  Populærvitenskapelig artikkel

1999

• Lien, E; Nonstad, Unni; Sundan, A; Espevik, Terje. (1999) Polymorphonuchlear of Fas and Fas-Ligand expression in NK cells by cytokines and the involved of Fas-Ligand in NK/LAK cell-mediated cytotoxicity. Cytokine
  Vitenskapelig artikkel
• Johnsen, A-C; Steinkjer, B; Egeberg, Kathrine; Sundan, A; Espevik, Terje. (1999) The role of international-2 in regulation the sensitivity of natural killer celler for Fas-mediated apoptosis. European Journal of Haematology
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (1999) Behandling av diabetes mellitus med transplantasjon av immunbeskyttet øyvev fra pancreas. Tidsskrift for Den norske legeforening
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Vatten, Lars Johan; Espevik, Terje. (1999) Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease. Acta Dermato-Venereologica
  Vitenskapelig artikkel
• Aukrust, Pål; Haug, Charlotte J.; Ueland, Thor; Lien, Egil; Müller, Fredrik; Espevik, Terje. (1999) Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: Indication of normalization of the bone-remodeling process during highly active antiretroviral therapy. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Vitenskapelig artikkel
• Heine, Holger; Delude, Russell L.; Monks, Biran G.; Espevik, Terje; Golenbock, Douglas T.. (1999) Bacterial lipopolysaccharide induces expression of the stress response genes Hop and H411. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation
  Vitenskapelig artikkel
• Børset, Magne; Hjort-Hansen, Henrik; Johnsen, Ann-Charlotte; Seidel, Carina; Waage, Anders; Espevik, Terje. (1999) Apoptosis, proliferation and NF-k(kappa)B activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor. European Journal of Haematology
  Vitenskapelig artikkel
• Aukrust, Pål; Müller, Fredrik; Lien, Egil; Nordøy, Ingvild; Liabakk, Nina-Beate; Kvale, Dag. (1999) Tumor necrosis factor (TNF) system levels in human immunodificiency virus-infected patients during highly active antiretroviral therapy: Perisistent TNF activation is associated with virologic and immunologic treatment failure. Journal of Infectious Diseases
  Vitenskapelig artikkel
• Gullestad, Lars; Aukrust, Pål; Ueland, Thor; Espevik, T; Yee, G.; Vagelos, R.. (1999) Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure. Journal of the American College of Cardiology
  Vitenskapelig artikkel
• Aukrust, Pål; Haug, Charlotte J.; Ueland, Thor; Lien, Egil; Muller, Fredrik; Espevik, T. (1999) Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: indication of normalization of the bone-remodeling process during highly active antiretroviral therapy. Journal of Clinical Endocrinology and Metabolism (JCEM)
  Vitenskapelig artikkel
• Aukrust, Pål; Ueland, Thor; Lien, Egil; Bendtzen, Klaus; Muller, Fredrik; Andreassen, Arne K.. (1999) Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. American Journal of Cardiology
  Vitenskapelig artikkel
• Haux, Johan; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo; Sundan, Anders. (1999) The role of IL-2 in regulating the sensitivity of NK cells for Fas-mediated apoptosis. Cancer Immunology and Immunotherapy
  Vitenskapelig artikkel
• Lien, Egil; Sellati, Timothy J.; Yoshimura, Atsutosi; Flo, Trude Helen; Rawadi, Georges; Finberg, Robert W.. (1999) Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Sundan, Anders. (1999) Regulation of APO-2 ligand /Trail expression in NK cells - involvement in NK cell-mediated cytotoxicity. Cytokine
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild. (1999) Transplantation of alginate microcapsules. Transplantation
  Vitenskapelig artikkel
• Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo. (1999) Regulation of Apo-2 Ligand/Trail expression in NK cells - Involvement in NK cell mediated cytotoxicity. Cytokine
  Vitenskapelig artikkel
• Aukrust, Pål; Muller, Fredrik; Lien, Egil; Nordøy, Ingvild; Liabakk, Nina-Beate; Kvale, Dag. (1999) Tumor necrosis factor (TNF) system in human immunodeficiency virus-infected patients during highly active antiretroviral therapy (HAART): Persistent TNF activation is associated with virologic and immunologic treatment failure. Journal of Infectious Diseases
  Vitenskapelig artikkel

1998

• Lien, Egil; Aukrust, Pål; Sundan, Andreas; Muller, Fredrik; Frøland, Stig Sophus; Espevik, T. (1998) Elevated levels of serum-soluble CD14 in human immonudeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood
  Vitenskapelig artikkel
• Lien, E; Sundan, A; Aukrust, P; Frøland, S; Espevik, Terje. (1998) Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood
  Vitenskapelig artikkel
• Thommesen, Liv; Sjursen, Wenche; Gåsvik, Kathrine; Hanssen, Wenche; Brekke, Ole-Lars; Skattebøl, Lars. (1998) Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1. Journal of Immunology
  Vitenskapelig artikkel
• Berntzen, G.; Flo, T; Medvedev, A; Kilaas, L; Skjåk-Bræk, Gudmund; Sundan, A. (1998) The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles. Clinical and Vaccine Immunology
  Vitenskapelig artikkel
• Halaas, Øyvind; Vik, R; Espevik, Terje. (1998) Induction of Fas ligand in murine bone marrow NK cells by bacterial polysaccharides. Immunology
  Vitenskapelig artikkel
• Ingalls, RR; Monks, BG; Savedra R, [Mangler fornavn]; Christ, WJ; Delude, RL; Medvedev, AE. (1998) CD11/CD18 and CD14 share a common lipid A signaling pathway. Journal of Immunology
  Vitenskapelig artikkel
• Medvedev, AE; Flo, T; Vogel, SN; Robin, R; Golenbock, DT; Teti, G. (1998) Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls. Journal of Immunology
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Espevik, Terje; Sundan, A. (1998) Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus. Acta Dermato-Venereologica
  Vitenskapelig artikkel
• Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo. (1998) Regulation of Apo-2 Ligand/TRAIL expression in NK cells - Involvement in NK cell mediated cytotoxicity. Journal of Interferon and Cytokine Research
  Sammendrag/abstract

1997

• Hestad, Kjetil; Aukrust, Pål; Muller, Fredrik; Lien, Egil; Bjerkeli, Vigdis; Espevik, T. (1997) Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1  infection: Low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load. Blood
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Thu, Beate; Espevik, Terje; Skjåk-Bræk, Gudmund. (1997) Alginate polylysine microcapsules as immune barrer : permeability of cytokines and immmunoglobulins over the capsule membrane. Cell Transplantation
  Vitenskapelig artikkel
• Sandler, Stellan; Andersson, Arne; Eizirik, Décio L.; Hellerström, Claes; Espevik, Terje; Kulseng, Siri. (1997) Assessment of insulin secretion in vitro from microencapsulated fetal procine islet-like cell clusters and rat, mouse, and human pancreatic islets. Transplantation
  Vitenskapelig artikkel
• Jahr, Tove Gullstein; Ryan, Liv; Sundan, Anders; Lichenstein, Henri S.; Skjåk-Bræk, Gudmund; Espevik, Terje. (1997) Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/ permeability-increasing factor. Infection and Immunity
  Vitenskapelig artikkel
• Aukrust, Pål; Hestad, Kjetil; Lien, Egil; Bjerkeli, Vigdis; Nordøy, Ingvild; Espevik, T. (1997) Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-_a activity in human immunodeficiency virus type 1 infection. Journal of Infectious Diseases
  Vitenskapelig artikkel
• Medvedev, Andrei E.; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo. (1997) Regulation of Fas and Fas-Ligand expression in NK cells by cytokines and the involvement of Fas-Ligand in NK/LAK cell-mediated cytotoxicity. Cytokine
  Vitenskapelig artikkel
• Hestdal, Kjetil; Aukrust, Pål; Müller, Fredrik; Lien, Egil; Bjerkeli, Vigdis; Espevik, Terje. (1997) Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection : low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load. Blood
  Vitenskapelig artikkel
• Aukrust, Pål; Hestdal, Ketil; Lien, Egil; Bjerkeli, Vigdis; Nordøy, Ingvild; Espevik, Terje. (1997) Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-alpha activity in human immunodeficiency virus type 1 infection. Journal of Infectious Diseases
  Vitenskapelig artikkel
• Jackson, A.M.; Lien, Egil; Alexandroff, A.B.; Espevik, Terje; James, K.; Selby, P.J.. (1997) Soluble urinary CD14 after intravesical bacille Calmette-Guérin immunotherapy for carcinoma in situ. British Journal of Urology
  Vitenskapelig artikkel

1996

• Børset, Magne; Lien, Egil; Espevik, Terje; Helseth, Eirik; Waage, Anders; Sundan, Anders. (1996) Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Følling, Ivar; Espevik, Terje. (1996) TNF production from peripheral blood mononuclear cells in diabetic patients after stimulation with alginate and lipopolysaccharide. Scandinavian Journal of Immunology
  Vitenskapelig artikkel
• Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, P.; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. I, Interaction between alginate and polycation. Biomaterials
  Vitenskapelig artikkel
• Haug, Charlotte J.; Aukrust, Pål; Lien, Egil; Muller, Fredrik; Espevik, T; Frøland, Stig Sophus. (1996) Disseminated Mycobacterium avium complex (MAC) infection in AIDS: Immunopathogenic significance of an activated tumor necrosis factor (TNF) system and depressed serum levels of 1,25-dihydroxyvitamin D. Journal of Infectious Diseases
  Vitenskapelig artikkel
• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne Karin; Muller, Fredrik; Haug, Charlotte J.; Espevik, T. (1996) Persistent activation of tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency - Possible immunologic and clinical concensus. Blood
  Vitenskapelig artikkel
• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne Karin; Muller, Fredrik; Haug, Charlotte J.; Espevik, T. (1996) Persistant Activation of The Tumor Nevcrosis Factor System in a Subgroup of Patients With Common Varable Immunodeficincy - Possible Immunological and Clinical and Consequences. Blood
  Vitenskapelig artikkel
• Medvedev, Andrei E.; Lægreid, Astrid; Sundan, Anders; Espevik, Terje. (1996) A non-competitive P55 TNF receptor antibody enhances the specific activity of Lymphotoxin-_a. Scandinavian Journal of Immunology
  Vitenskapelig artikkel
• Haug, Charlotte J.; Aukrust, Pål; Lien, Egil; Müller, Fredrik; Espevik, Terje; Frøland, Stig S.. (1996) Disseminated Mycobacterium avium complex infection in AIDS : immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D. Journal of Infectious Diseases
  Vitenskapelig artikkel
• Børset, Magne; Medvedev, Andrei E.; Sundan, Anders; Espevik, Terje. (1996) The role of the two TNF receptors in proliferation, NF-_KB activation and discrimination between TNF and LT_a signalling in the human myeloma cell line OH-2. Cytokine
  Vitenskapelig artikkel
• Medvedev, Andrei E.; Espevik, Terje; Ranges, Gerald; Sundan, Anders. (1996) Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin _a effects. Journal of Biological Chemistry
  Vitenskapelig artikkel
• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne K.; Müller, Fredrik; Haug, Charlotte J.; Espevik, Terje. (1996) Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency : possible immunologic and clinical consequences. Blood
  Vitenskapelig artikkel
• Skjåk-Bræk, Gudmund; Espevik, Terje. (1996) Application of alginate gels in biotechnology and biomedicine. Carbohydrates in Europe
  Vitenskapelig artikkel
• Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, Patrick; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. II, Some functional properties. Biomaterials
  Vitenskapelig artikkel

1995

• Skjåk-Bræk, Gudmund; Espevik, Terje; Otterlei, Marit; Smidsrød, Olav; Soon-Shiong, P.. (1995) Homologous guluronic acid alginate coating composition for in vivo application and implantation and method using the same. US-Patent 5459 054, Oct. 1995
  Rapport
• Lien, Egil; Liabakk, Nina-Beate; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Nonstad, Unni; Sundan, Anders. (1995) Polymorphonuclear granulocytes enhance lipopolysaccharide-induced p75 tumor necrosis factor receptor release from mononuclear cells. European Journal of Immunology
  Vitenskapelig artikkel
• Skjermo, Jorunn; Defoort, Thomas; Dehasque, Marleen; Espevik, Terje; Olsen, Yngvar; Skjåk-Bræk, Gudmund. (1995) Immunostimulation of juvenile turbot (Scophthalmus maximus L.) using an alginate with high mannuronic acid content administered via the live food organism Artemia. Fish and Shellfish Immunology
  Vitenskapelig artikkel
• Arntzen, KJ; Liabakk, N-B; Jacobsen, G.; Espevik, Terje; Austgulen, Rigmor. (1995) Soluble tumor necrosis factor receptor in serum and urine througout normal pregnancy and delivery. American Journal of Reproductive Immunology
  Vitenskapelig artikkel
• Samuelsen, Anne Berit; Paulsen, Berit Smestad; Wold, Jens Krisitian; Otsuka, Hanako; Yamada, Haruki; Espevik, T. (1995) Isolation and partial characterization of biologically active polysaccharides from Plantago major L. Phytotherapy Research
  Vitenskapelig artikkel

1994

• Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1994) Cytokines in meningococcal disease. Baillière's Clinical Infectious Diseases
  Vitenskapelig artikkel
• Brekke, OL; Espevik, Terje; Bjerve, Kristian S. (1994) Butylated Hydroxyanisole Inhibits Tumor Necrosis Factor induced Cytotoxicity and Arachidonic Acid Release. Lipids
  Vitenskapelig artikkel
• Halgunset, J; Johnsen, H; Kjøllesdal, AM; Qvigstad, E; Espevik, Terje; Austgulen, Rigmor. (1994) Normal parturition at term is associated with subtle inflammatory reactions in-utero. European Journal of Obstetrics, Gynecology, and Reproductive Biology
  Vitenskapelig artikkel

1993

• Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1993) Compartmentalization of the TNF and IL-6 in meningitis and septic shock. Mediators of Inflammation
  Vitenskapelig artikkel
• Austgulen, Rigmor; Naume, B; Johnson, A-C; Espevik, Terje; Sundan, A. (1993) Gene expression and secretion of cytokines and cytokines from highly purified CD56* natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology
  Vitenskapelig artikkel
• Naume, Bjørn; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Espevik, Terje; Sundan, Anders. (1993) Gene expression and secretion of cytokines and cytokine receptors from hihgly purified CD56+ natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology
  Vitenskapelig artikkel
• Austgulen, Rigmor; Kjøllesdal, AM; Johnsen, H; Liabakk, N-B; Espevik, Terje. (1993) Soluble receptors for tumor necrosis factor: occurence in association with normal delivery at term. Obstetrics and Gynecology
  Vitenskapelig artikkel
• Liabakk, N-B; Lien, E; Sundan, A; Sunde, A; Austgulen, Rigmor; Espevik, Terje. (1993) High concentrations of the soluble p55 tumor necrosis factor receptor in human seminal plasma. Human Reproduction
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, N-B; Lien, E; Espevik, Terje. (1993) Increased levels of soluble TNF-alpha receptors in serum from pregnant women, and in serum and urine samples from newborns. Pediatric Research
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, N-B; Richardsen, W; Rahimipoor, S; Vatn, I; Espevik, Terje. (1993) Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal pregnancy. Placenta
  Sammendrag/abstract

1992

• Waage, A.; Halstensen, Alfred; Brandtzæg, P.; Espevik, T.. (1992) TNF in serum in patients with bacterial infections.
  Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
• Brandtzæg, P.; Halstensen, Alfred; Kierulf, P.; Espevik, T.; Waage, A.. (1992) Molecular mechanisms in the compartmentalized inflammatory response presenting as meningococcal meningitis or septic shock. Microbial Pathogenesis
  Vitenskapelig artikkel
• Soon-Shong, P.; Feldman, E.; Nelson, R.; Komtebedde, J.; Smidsrød, Olav; Skjåk-Bræk, Gudmund. (1992) Successful reversal of spontaneous diabetes in dogs by intraperitonal microencapsulated islets. Transplantation
  Vitenskapelig artikkel
• Brekke, OL; Shalaby, MR; Sundan, Anders; Espevik, Terje; Bjerve, Kristian S. (1992) Butylated hydroxyanisol specifically inhibits Tumor Necrosis Factor induced cytotoxicity and growth enhancement. Cytokine
  Vitenskapelig artikkel
• Brekke, OL; Espevik, Terje; Bardal, Tora; Bjerve, Kristian S. (1992) Effects of n-3 and n-6 fatty acids on Tumor Necrosis Factor cytotoxicity in WEHI fibrosarcoma cells. Lipids
  Vitenskapelig artikkel
• Austgulen, Rigmor; Espevik, Terje; Mecsei, R; Scott, H. (1992) Expression of receptors for tumor necrosis factor in human placenta at term. Acta Obstetricia et Gynecologica Scandinavica
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, N-B; Espevik, Terje. (1992) Sekresjon av løselige reseptorer for tumor nekrose faktor - en immunologisk buffermekanisme under svangerskap?. Tidsskrift for Den norske legeforening
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, NB; Brockhaus, M; Espevik, Terje. (1992) Soluble TNF receptors in amniotic fluid and in urine from pregnant women. Journal of Reproductive Immunology
  Vitenskapelig artikkel

1991

• Waage, A.; Brandtzæg, P.; Espevik, T.; Halstensen, Alfred. (1991) Current understanding of the pathogenesis of gram negative shock. Infectious Disease Clinics of North America
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, N-B; Scott, H; Brockhaus, M; Espevik, Terje. (1991) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. Placenta
  Sammendrag/abstract

1988

• Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1988) Synergistic growth inhibitory activity of tumor necrosis factor and interferon-alpha: contribution to the monocyte-derived cytostatic activity towards human leukemia K562 cells. Scandinavian Journal of Immunology
  Vitenskapelig artikkel
• Nissen-Meyer, J; Hofsli, E; Espevik, Terje; Austgulen, Rigmor. (1988) Involvement of tumor necrosis factor in cytotoxicity mediated by human monocytes. Natural immunity and cell growth regulation
  Vitenskapelig artikkel

1987

• Bjerve, Kristian S; Espevik, Terje; Kildahl-Andersen, O; Nissen-Meyer, J. (1987) Effect of free fatty acids on the cytolytic activity of tumor necrosis factor/¬monocyte-derived cytotoxic factor. APMIS - Journal of Pathologiy, Microbiology and Immunology
  Vitenskapelig artikkel
• Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1987) Comparison of recombinant tumor necrosis factor and the monocyte-derived cytotoxic factor (CF) which is involved in the monocyte-mediated cytotoxicity. Cancer Research
  Vitenskapelig artikkel
• Austgulen, Rigmor; Espevik, Terje; Nissen-Meyer, J. (1987) Fibroblast growth stimulatory activity from human monocytes: The contribution of tumor necrosis factor. Scandinavian Journal of Immunology
  Vitenskapelig artikkel
• Austgulen, Rigmor; Espevik, Terje; Degree, M. (1987) Monocyte-derived influence on growth of normal human fibroblasts: The contribution of tumor necrosis factor to growth inhibition. Scandinavian Journal of Immunology
  Vitenskapelig artikkel

1986

• Austgulen, Rigmor; Espevik, Terje; Hammerstrøm, J; Nissen-Meyer, J. (1986) Role of monocyte cytotoxic factor in cytolysis of actinomycin D treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells. Cancer Research
  Vitenskapelig artikkel
• Austgulen, Rigmor; Kildahl-Andersen, O; Espevik, Terje. (1986) Monocyte-mediated drug-dependent cellular cytotoxicity: Effects of different WEHI 164 target cell lines. Cancer Immunology and Immunotherapy
  Vitenskapelig artikkel
• Austgulen, Rigmor; Hammerstrøm , J; Espevik, Terje; Nissen-Meyer, J. (1986) Human monocyte cytotoxic factor mediates cytolysis of WEHI 164 cells. Cellular Immunology
  Vitenskapelig artikkel