2023

• Bjerkhaug, Aline; Granslo, Hildegunn Norbakken; Cavanagh, Jorunn Pauline; Høiland, Ina Isabella; Ludviksen, Judith K; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik; Klingenberg, Claus Andreas. (2023) Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model. Pediatric Research.
  Vitenskapelig artikkel

2022

• Johnson, Christina; Quach, Huy Quang; Lau, Corinna; Ekholt, Karin; Espevik, Terje; Woodruff, Trent M.; Pischke, Soeren; Mollnes, Tom Eirik; Nilsson, Per. (2022) Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood. Journal of Immunology. volum 208 (12).
  Vitenskapelig artikkel
• Nilsen, Kaja Elisabeth; Skjesol, Astrid; Kojen, June Frengen; Espevik, Terje; Stenvik, Jørgen; Yurchenko, Mariya. (2022) TIRAP/Mal Positively Regulates TLR8‐Mediated Signaling via IRF5 in Human Cells. Biomedicines. volum 10 (7).
  Vitenskapelig artikkel
• Pinto, Sneha M.; Subbannayya, Yashwanth; Kim, Hera; Hagen, Lars; Górna, Maria W; Nieminen, Anni I.; Bjørås, Magnar; Espevik, Terje; Kaynov, Denis; Kandasamy, Richard Kumaran. (2022) Multi-OMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells. iScience. volum 26 (1).
  Vitenskapelig artikkel

2021

• Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.; Woods, Russell L.; Bhowmick, Sabuj Chandra; Dohlman, Claes H.; Espevik, Terje; Chodosh, James; Gonzalez-Andrades, Miguel; Mollnes, Tom Eirik. (2021) Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses. Acta Biomaterialia. volum 127.
  Vitenskapelig artikkel
• Kim, Hera; Subbannayya, Yashwanth; Humphries, Fiachra; Skjesol, Astrid; Pinto, Sneha M.; Giambelluca, Miriam; Espevik, Terje; Fitzgerald, Katherine A.; Kandasamy, Richard Kumaran. (2021) UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis. PLOS ONE. volum 16 (10).
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Rahman, Jubayer; Kunz, Natalie; West, Erin; Freiwald, Tilo; Desai, Jigar V.; Merle, Nicolas; Gidon, Alexandre; Sporsheim, Bjørnar; Lionakis, Michail S.; Evensen, Kristin; Lindberg, Beate; Skagen, Karolina Ryeng; Skjelland, Mona; Singh, Parul; Haug, Markus; Ruseva, Marieta M.; Kolev, Martin; Bibby, Jack; Marshall, Olivia; O’Brien, Brett; Deeks, Nigel; Afzali, Behdad; Clark, Richard J.; Woodruff, Trent M.; Pryor, Mylton; Yang, Zhi-Hong; Remaley, Alan T.; Mollnes, Tom Eirik; Hewitt, Stephen M.; Yan, Bingyu; Kazemian, Majid; Kiss, Mate G.; Binder, Christoph J.; Halvorsen, Bente; Espevik, Terje; Kemper, Claudia. (2021) Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation. Science immunology. volum 6 (66).
  Vitenskapelig artikkel
• Trifonov, Lena; Yurchenko, Mariya; Skjesol, Astrid; Cohen, Guy; Espevik, Terje; Korshin, Edward E.; Grøvdal, Lene Melsæther; Husebye, Harald; Gruzman, Arie. (2021) Benzyl-para-di-[5-methyl-4-(n-octylamino) pyrimidin-2(1H)one] as an interferon beta (IFN-β) modulator. Molecular diversity.
  Vitenskapelig artikkel

2020

• Ehrnstrøm, Birgitta; Kojen, June Frengen; Giambelluca, Miriam; Ryan, Liv; Moen, Siv Helen; Hu, Zhenyi; Yin, Hang; Mollnes, Tom Eirik; Damås, Jan Kristian; Espevik, Terje; Stenvik, Jørgen. (2020) TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria. Journal of Leukocyte Biology. volum 107 (4).
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Bakke, Siril Skaret; Gregersen, Ida; Holm, Sverre; Sandanger, Øystein; Orrem, Hilde Lang; Sporsheim, Bjørnar; Ryan, Liv; Kong, Xiang Yi; Dahl, Tuva Børresdatter; Skjelland, Mona; Sørensen, Kirsten; Rokstad, Anne Mari A.; Yndestad, Arne; Latz, Eicke; Gullestad, Lars; Andersen, Geir Øystein; Damås, Jan Kristian; Aukrust, Pål; Mollnes, Tom Eirik; Halvorsen, Bente; Espevik, Terje. (2020) Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis. EBioMedicine. volum 60:102985.
  Vitenskapelig artikkel

2019

• Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Retterstøl, Kjetil; Henriksen, Tore; Bollerslev, Jens; Espevik, Terje; Aukrust, Pål; Halvorsen, Bente; Holven, Kirsten Bjørklund. (2019) Serum Omega-6 Fatty Acids and Immunology-Related Gene Expression in Peripheral Blood Mononuclear Cells: A Cross-Sectional Analysis in Healthy Children. Molecular Nutrition & Food Research. volum 63 (7).
  Vitenskapelig artikkel
• Gravastrand, Caroline S.; Steinkjer, Bjørg; Halvorsen, Bente; Landsem, Anne; Skjelland, Mona; Jacobsen, Eva Astrid; Woodruff, Trent M.; Lambris, John D.; Mollnes, Tom Eirik; Brekke, Ole-Lars; Espevik, Terje; Rokstad, Anne Mari. (2019) Cholesterol Crystals Induce coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor. Journal of Immunology. volum 203 (4).
  Vitenskapelig artikkel
• Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar; Ludviksen, Judith K; Fure, Hilde; Espevik, Terje; Moen, Anders; Andersen, Jan Terje; Mollnes, Tom Eirik. (2019) NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies. mAbs. volum 12:e1686319 (1).
  Vitenskapelig artikkel
• Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi; Michelsen, Annika; Otterdal, Kari; Yndestad, Arne; Broch, Kaspar; Gullestad, Lars; Nyman, Tuula Anneli; Bendz, Bjørn; Eritsland, Jan; Hoffmann, Pavel; Skagen, Karolina Ryeng; Gonçalves, Isabel; Nilsson, Jan; Grenegård, Magnus; Poreba, Marcin; Drag, Marcin; Seljeflot, Ingebjørg; Sporsheim, Bjørnar; Espevik, Terje; Skjelland, Mona; Johansen, Harald Thidemann; Solberg, Rigmor; Aukrust, Pål; Björbacka, Harry; Andersen, Geir Øystein; Halvorsen, Bente. (2019) Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis.
  Vitenskapelig artikkel
• Moen, Siv Helen; Ehrnstrøm, Birgitta; Kojen, June Frengen; Yurchenko, Mariya; Beckwith, Kai Sandvold; Afset, Jan Egil; Damås, Jan Kristian; Hu, Zhenyi; Yin, Hang; Espevik, Terje; Stenvik, Jørgen. (2019) Human Toll-like receptor 8 (TLR8) is an important sensor of pyogenic bacteria, and is attenuated by cell surface TLR signaling. Frontiers in Immunology. volum 10:1209 (May).
  Vitenskapelig artikkel
• Narverud, Ingunn; Christensen, Jacob J.; Bakke, Siril Skaret; Ulven, Stine Marie; Rundblad, Amanda; Aukrust, Pål; Espevik, Terje; Bogsrud, Martin Prøven; Retterstøl, Kjetil; Ueland, Thor; Halvorsen, Bente; Holven, Kirsten Bjørklund. (2019) Profiling of immune-related gene expression in children with familial hypercholesterolaemia. Journal of Internal Medicine.
  Vitenskapelig artikkel
• Pilely, Katrine; Bakke, Siril Skaret; Palarasah, Yaseelan; Skjoedt, Mikkel-Ole; Bartels, Emil D.; Espevik, Terje; Garred, Peter. (2019) Alpha-cyclodextrin inhibits cholesterol crystal-induced complement-mediated inflammation: A potential new compound for treatment of atherosclerosis. Atherosclerosis. volum 283.
  Vitenskapelig artikkel
• Skjeflo, Espen Waage; Christiansen, Dorte; Landsem, Anne; Stenvik, Jørgen; Woodruff, T. M.; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2019) Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14. Molecular Immunology. volum 112.
  Vitenskapelig artikkel
• Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther; Agliano, Federica; Patane, Francesco; Lentini, Germana; Kim, Hera; Teti, Giuseppe; Sharma, Aditya Kumar; Kandasamy, Richard Kumaran; Sporsheim, Bjørnar; Starheim, Kristian K.; Golenbock, Douglas T.; Stenmark, Harald; McCaffrey, Mary; Espevik, Terje; Husebye, Harald. (2019) The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2. PLoS Pathogens. volum 15:e1007684 (3).
  Vitenskapelig artikkel
• Thomas, Anub Mathew; Gerogianni, Alexandra; McAdam, Martin Berner; Fløisand, Yngvar; Lau, Corinna; Espevik, Terje; Nilsson, Per; Mollnes, Tom Eirik; Barratt-Due, Andreas. (2019) Complement component C5 and TLR molecule CD14 mediate heme-induced thromboinflammation in human blood. Journal of Immunology. volum 203 (6).
  Vitenskapelig artikkel

2018

• Bösl, Korbinian; Giambelluca, Miriam; Haug, Markus; Bugge, Marit; Espevik, Terje; Kandasamy, Richard Kumaran; Bergstrøm, Bjarte Aune. (2018) Coactivation of TLR2 and TLR8 in primary human monocytes triggers a distinct inflammatory signaling response. Frontiers in Physiology. volum 9 (MAY).
  Vitenskapelig artikkel
• Christ, Anette; Günther, Patrick; Lauterbach, Mario A.R.; Duewell, Peter; Biswas, Debjani; Pelka, Karin; Scholz, Claus J.; Oosting, Marije; Haendler, Kristian; Baßler, Kevin; Klee, Kathrin; Schulte-Schrepping, Jonas; Ulas, Thomas; Moorlag, Simone J.C.F.M.; Kumar, Vinod; Park, Min Hi; Joosten, Leo A.B.; Groh, Laszlo A.; Riksen, Niels P.; Espevik, Terje; Schlitzer, Andreas; Li, Yang; Fitzgerald, Michael L.; Netea, Mihai G.; Schultze, Joachim L.; Latz, Eicke. (2018) Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell. volum 172 (1-2).
  Vitenskapelig artikkel
• Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar; Holte, Espen; Ryan, Liv; Amundsen, Brage H.; Bendz, Bjørn; Aakhus, Svend; Espevik, Terje; Halvorsen, Bente; Mollnes, Tom Eirik; Wiseth, Rune; Gullestad, Lars; Aukrust, Pål; Damås, Jan Kristian. (2018) Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction. International Journal of Cardiology. volum 271.
  Vitenskapelig artikkel
• Landsem, Anne; Fure, Hilde; Ludviksen, Judith K; Christiansen, Dorte; Lau, Corinna; Mathisen, Monica Dammen; Bergseth, Grete; Nymo, Stig Haugset; Lappegård, Knut Tore; Woodruff, T. M.; Espevik, Terje; Mollnes, Tom Eirik; Brekke, Ole-Lars. (2018) Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4. Clinical and Experimental Immunology.
  Vitenskapelig artikkel
• Nejati Moharrami, Neda; Tande, Erlend Bjørkøy; Ryan, Liv; Espevik, Terje; Boyartchuk, Victor. (2018) RORα controls inflammatory state of human macrophages. PLOS ONE. volum 13 (11).
  Vitenskapelig artikkel
• Orrem, Hilde Lang; Nilsson, Per; Pischke, Søren Erik; Kleveland, Ola; Yndestad, Arne; Ekholt, Karin; Damås, Jan Kristian; Espevik, Terje; Bendz, Bjørn; Halvorsen, Bente; Gregersen, Ida; Wiseth, Rune; Andersen, Geir Øystein; Ueland, Thor; Gullestad, Lars; Aukrust, Pål; Barratt-Due, Andreas; Mollnes, Tom Eirik. (2018) IL-6 receptor inhibition by tocilizumab attenuated expression of C5a receptor 1 and 2 in non-ST-elevation myocardial infarction. Frontiers in Immunology. volum 9.
  Vitenskapelig artikkel
• Skjeflo, Espen Waage; Christiansen, Dorte; Fure, Hilde; Ludviksen, Judith K; Woodruff, Trent M.; Espevik, Terje; Nielsen, Erik Waage; Brekke, Ole-Lars; Mollnes, Tom Eirik. (2018) Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation. Journal of Thrombosis and Haemostasis. volum 16 (5).
  Vitenskapelig artikkel
• Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug; Saugstad, Ola Didrik; Berglund, Magnus M.; Strömberg, Patrik; Lau, Corinna; Espevik, Terje; Jansen, Johan Høgset; Castellheim, Albert; Mollnes, Tom Eirik; Barratt-Due, Andreas. (2018) Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome. Neonatology. volum 113 (4).
  Vitenskapelig artikkel
• Yurchenko, Mariya; Skjesol, Astrid; Ryan, Liv; Richard, Gabriel Mary; Kandasamy, Richard Kumaran; Wang, Ninghai; Terhorst, Cox; Husebye, Harald; Espevik, Terje. (2018) SLA MF1 is required for TLR4-mediated TRAM-TRIF- dependent signaling in human macrophages. Journal of Cell Biology. volum 217 (4).
  Vitenskapelig artikkel

2017

• Bakke, Siril Skaret; Aune, Marie Hjelmseth; Niyonzima, Nathalie; Pilely, Katrine; Ryan, Liv; Skjelland, Mona; Garred, Peter; Aukrust, Pål; Halvorsen, Bente; Latz, Eicke; Damås, Jan Kristian; Mollnes, Tom Eirik; Espevik, Terje. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology. volum 199 (8).
  Vitenskapelig artikkel
• Barratt-Due, Andreas; Pischke, Søren Erik; Nilsson, Per; Espevik, Terje; Mollnes, Tom Eirik. (2017) Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets. Journal of Leukocyte Biology. volum 101 (1).
  Vitenskapelig oversiktsartikkel/review
• Bugge, Marit; Bergstrøm, Bjarte; Eide, Oda K.; Solli, Helene; Kjønstad, Ingrid Fadum; Stenvik, Jørgen; Espevik, Terje; Nilsen, Nadra J.. (2017) Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Selective Cytokine Production and Promotes Invasiveness. Journal of Biological Chemistry. volum 292 (37).
  Vitenskapelig artikkel
• Ehrnstrøm, Birgitta; Beckwith, Kai Sandvold; Yurchenko, Mariya; Moen, Siv Helen; Kojen, June Frengen; Lentini, Germana; Teti, Guiseppe; Damås, Jan Kristian; Espevik, Terje; Stenvik, Jørgen. (2017) Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages. Frontiers in Immunology. volum 8.
  Vitenskapelig artikkel
• Espada Serrano, Sandra; Stavik, Benedicte; Holm, Sverre; Sagen, Ellen Lund; Bjerkeli, Vigdis; Skjelland, Mona; Dahl, Tuva Børresdatter; Espevik, Terje; Kanse, Sandip; Sandset, Per Morten; Skretting, Grethe; Halvorsen, Bente. (2017) Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages. Biochemical and Biophysical Research Communications - BBRC. volum 491 (2).
  Vitenskapelig artikkel
• Espevik, Terje. (2017) Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation. Journal of Immunology.
  Vitenskapelig artikkel
• Gravastrand, Caroline; Hamad, Shamal; Fure, Hilde; Steinkjer, Bjørg; Ryan, Liv; Oberholzer, José; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje; Brekke, Ole-Lars; Rokstad, Anne Mari. (2017) Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII. Acta Biomaterialia. volum 58.
  Vitenskapelig artikkel
• Gregersen, Ida; Sandanger, Øystein; Askevold, Erik Tandberg; Sagen, Ellen Lund; Yang, Kuan; Holm, Sverre; Pedersen, Turid Margrethe; Skjelland, Mona; Krohg-Sørensen, Kirsten; Hansen, Trond Vidar; Dahl, Tuva Børresdatter; Otterdal, Kari; Espevik, Terje; Aukrust, Pål; Yndestad, Arne; Halvorsen, Bente. (2017) Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation. PLOS ONE. volum 12 (11).
  Vitenskapelig artikkel
• Hellerud, Bernt C; Orrem, Hilde Lang; Dybwik, Knut Gustav; Pischke, Søren Erik; Barratt-Due, Andreas; Castellheim, Albert; Fure, Hilde; Bergseth, Grete; Christiansen, Dorte; Nunn, Miles A.; Espevik, Terje; Lau, Corinna; Brandtzæg, Petter; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2017) Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis. Journal of Intensive Care. volum 5:21.
  Vitenskapelig artikkel
• Lunde, Ngoc Nguyen Dieu; Holm, Sverre; Dahl, Tuva Børresdatter; Inass, Elyouncha; Sporsheim, Bjørnar; Gregersen, Ida; Abbas, Azhar; Skjelland, Mona; Espevik, Terje; Solberg, Rigmor; Johansen, Harald Thidemann; Halvorsen, Bente. (2017) Increased levels of legumain in plasma and plaques from patients with carotid atherosclerosis. Atherosclerosis. volum 257.
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Halvorsen, Bente; Sporsheim, Bjørnar; Garred, Peter; Aukrust, Pål; Mollnes, Tom Eirik; Espevik, Terje. (2017) Complement activation by cholesterol crystals triggers a subsequent cytokine response. Molecular Immunology. volum 84.
  Vitenskapelig artikkel
• Stavik, Benedicte; Espada, Sandra; Holm, Sverre; Bjerkeli, Vigdis; Sandset, Per Morten; Dahl, Tuva Børresdatter; Skjelland, Mona; Espevik, Terje; Iversen, Nina; Skretting, Grethe; Halvorsen, Bente. (2017) TFPI in human atherosclerotic plaques. Research and Practice in Thrombosis and Haemostasis. volum 1 (s1).
  Sammendrag/abstract
• Stavik, Benedicte; Holm, Sverre; Espada Serrano, Sandra; Iversen, Nina; Sporsheim, Bjørnar; Bjerkeli, Vigdis; Dahl, Tuva Børresdatter; Sandset, Per Morten; Skjelland, Mona; Espevik, Terje; Skretting, Grethe; Halvorsen, Bente. (2017) Increased expression of TFPI in human carotid stenosis. Thrombosis Research. volum 155.
  Vitenskapelig artikkel

2016

• Gustavsen, Alice; Nymo, Stig Haugset; Landsem, Anne; Christiansen, Dorte; Ryan, Liv; Husebye, Harald; Lau, Corinna; Pischke, Søren Erik; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2016) Combined inhibition of complement and CD14 attenuates bacteria-induced inflammation in human whole blood more efficiently than antagonizing the toll-like receptor 4-MD2 complex. Journal of Infectious Diseases. volum 214 (1).
  Vitenskapelig artikkel
• Kleveland, Ola; Kunszt, Gabor; Bratlie, Marte; Ueland, Thor; Broch, Kaspar; Holte, Espen; Michelsen, Annika; Bendz, Bjørn; Amundsen, Brage H.; Espevik, Terje; Aakhus, Svend; Damås, Jan Kristian; Aukrust, Pål; Wiseth, Rune; Gullestad, Lars. (2016) Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial. European Heart Journal. volum 37 (30).
  Vitenskapelig artikkel
• Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo; Espevik, Terje; Nordbø, Svein Arne; Døllner, Henrik; Anthonsen, Marit Walbye. (2016) Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis. PLOS ONE. volum 11:e0155484 (5).
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Freeley, Simon; Arbore, Giuseppina; Le Friec, Gaelle; Lappegård, Knut Tore; Mollnes, Tom Eirik; Kemper, Claudia; Espevik, Terje. (2016) The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes. Immunobiology.
  Sammendrag/abstract
• Nymo, Stig Haugset; Gustavsen, Alice; Nilsson, Per; Lau, Corinna; Espevik, Terje; Mollnes, Tom Eirik. (2016) Human endothelial cell activation by Escherichia coli and staphylococcus aureus is mediated by TNF and IL-1β secondarily to activation of C5 and CD14 in whole blood. Journal of Immunology. volum 196 (5).
  Vitenskapelig artikkel
• Pilely, Katrine; Rosbjerg, Anne; Genster, Ninette; Gál, Peter; Pál, Gábor; Halvorsen, Bente; Holm, Sverre; Aukrust, Pål; Bakke, Siril Skaret; Sporsheim, Bjørnar; Nervik, Ingunn; Niyonzima, Nathalie; Bartels, Emil D.; Stahl, Gregory L.; Mollnes, Tom Eirik; Espevik, Terje; Garred, Peter. (2016) Cholesterol crystals activate the lectin complement pathway via ficolin-2 and mannose-binding lectin: Implications for the progression of atherosclerosis. Journal of Immunology. volum 196 (12).
  Vitenskapelig artikkel
• Varghese, Paramel G; Folkersen, Lasse; Strawbridge, Rona J.; Halvorsen, Bente; Yndestad, Arne; Ranheim, Trine; Krogh-Sørensen, Kristin; Skjelland, Mona; Espevik, Terje; Aukrust, Pål; Lengquist, Mariette; Hedin, Ulf; Jansson, Jan-Håkan; Fransen, Karin; Hansson, Göran K.; Eriksson, Per; Sirsjø, Allan. (2016) NLRP3 inflammasome expression and activation in human atherosclerosis. Journal of the American Heart Association (JAHA). volum 5:e003031 (5).
  Vitenskapelig artikkel
• Zimmer, Sebastian; Grebe, Alena; Bakke, Siril Skaret; Bode, Niklas; Halvorsen, Bente; Ulas, Thomas; Skjelland, Mona; De Nardo, Dominic; Labzin, Larisa I.; Kerksiek, Anja; Hempel, Chris; Heneka, Michael T.; Hawxhurst, Victoria; Fitzgerald, Michael L.; Trebicka, Jonel; Björkhem, Ingemar; Gustafsson, Jan Åke; Westerterp, Marit; Tall, Alan R.; Wright, Samuel D.; Espevik, Terje; Schultze, Joachim L.; Nickenig, Georg; Lütjohann, Dieter; Latz, Eicke. (2016) Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Science Translational Medicine. volum 8 (333).
  Vitenskapelig artikkel
• Ørning, Mathias Pontus; Hoem, Kine Samset; Coron, Abba Elizabeth; Skjåk-Bræk, Gudmund; Mollnes, Tom Eirik; Brekke, Ole Lars; Espevik, Terje; Rokstad, Anne Mari. (2016) Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation. Journal of Controlled Release. volum 229.
  Vitenskapelig artikkel

2015

• Klein, Dionne; Skjesol, Astrid; Kers-Rebel, Esther D.; Sherstova, Tatyana; Sporsheim, Bjørnar; Egeberg, Kjartan Wøllo; Stokke, Bjørn Torger; Espevik, Terje; Husebye, Harald. (2015) CD14, TLR4 and TRAM Show Different Trafficking Dynamics During LPS Stimulation. Traffic: The moving front of cell biology. volum 16 (7).
  Vitenskapelig artikkel
• Bergstrøm, Bjarte; Aune, Marie Hjelmseth; Awuh, Jane Atesoh; Kojen, June Frengen; Blix, Kjetil Jordahl; Ryan, Liv; Flo, Trude Helen; Mollnes, Tom Eirik; Espevik, Terje; Stenvik, Jørgen. (2015) TLR8 senses Staphylococcus aureus RNA in human primary monocytes and macrophages and induces IFN-β production via a TAK1-IKKβ-IRF5 signaling pathway. Journal of Immunology. volum 195 (3).
  Vitenskapelig artikkel
• Egge, Kjetil Hagene; Barratt-Due, Andreas; Nymo, Stig Haugset; Lindstad, Julie Katrine; Pharo, Anne Margrethe; Lau, Corinna; Espevik, Terje; Thorgersen, Ebbe Billmann; Mollnes, Tom Eirik. (2015) The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load. Clinical and Experimental Immunology. volum 181 (3).
  Vitenskapelig artikkel
• Espevik, Terje. (2015) Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation. Journal of Immunology.
  Vitenskapelig artikkel
• Hovland, Anders; Jonasson, Lena; Garred, Peter; Yndestad, Arne; Aukrust, Pål; Lappegård, Knut Tore; Espevik, Terje; Mollnes, Tom Eirik. (2015) The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis. Atherosclerosis. volum 241 (2).
  Vitenskapelig oversiktsartikkel/review
• Lau, Corinna; Nygård, Ståle; Fure, Hilde; Olstad, Ole Kristoffer; Holden, Marit; Lappegård, Knut Tore; Brekke, Ole Lars; Espevik, Terje; Hovig, Johannes Eivind; Mollnes, Tom Eirik. (2015) CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray. PLOS ONE. volum 10 (2).
  Vitenskapelig artikkel
• Lau, Corinna; Olstad, Ole Kristoffer; Holden, Marit; Nygård, Ståle; Fure, Hilde; Lappegård, Knut Tore; Brekke, Ole Lars; Espevik, Terje; Hovig, Johannes Eivind; Mollnes, Tom Eirik. (2015) Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response. Genomics Data. volum 5.
  Vitenskapelig artikkel
• Nilsen, Nadra; Gregory I., Vladimer; Stenvik, Jørgen; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit; Bergstrøm, Bjarte; Conlon, Joseph; Husebye, Harald; Amy, Hise; Fitzgerald, Katherine A.; Espevik, Terje; Lien, Egil. (2015) A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling. Journal of Biological Chemistry. volum 290 (6).
  Vitenskapelig artikkel
• Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Rokstad, Anne Mari; Wright, Samuel; Damås, Jan Kristian; Mollnes, Tom Eirik; Latz, Eicke; Espevik, Terje. (2015) Reconstituted high-density lipoprotein attenuates cholesterol crystal-induced inflammatory responses by reducing complement activation. Journal of Immunology. volum 195 (1).
  Vitenskapelig artikkel
• Skjeflo, Espen Waage; Sagatun, Caroline; Dybwik, Knut; Aam, Sturla; Urving, Sven Haakon; Nunn, Miles A.; Fure, Hilde; Lau, Corinna; Brekke, Ole Lars; Huber-Lang, Markus; Espevik, Terje; Barratt-Due, Andreas; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2015) Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis. Critical Care. volum 19:415.
  Vitenskapelig artikkel
• Sponaas, Anne-Marit; Moen, Siv Helen; Liabakk, Nina-Beate; Feyzi, Emadoldin; Holien, Toril; Kvam, Solveig; Grøseth, Lill Anny Gunnes; Størdal, Berit Fladvad; Buene, Glenn; Espevik, Terje; Waage, Anders; Standal, Therese; Sundan, Anders. (2015) The proportion of CD16+CD14dim monocytes increases with tumor cell load in bone marrow of patients with multiple myeloma. Immunity,Inflammation and Disease. volum 3 (2).
  Vitenskapelig artikkel

2014

• Arlov, Øystein; Aachmann, Finn Lillelund; Sundan, Anders; Espevik, Terje; Skjåk-Bræk, Gudmund. (2014) Heparin-Like Properties of Sulfated Alginates with Defined Sequences and Sulfation Degrees. Biomacromolecules. volum 15 (7).
  Vitenskapelig artikkel
• Franklin, Bernardo S; Bossaller, Lukas; De Nardo, Dominic; Ratter, Jacqueline M; Stutz, Andrea; Engels, Gudrun; Brenker, Christoph; Nordhoff, Mark; Mirandola, Sandra R; Al-Amoudi, Ashraf; Mangan, Matthew S; Zimmer, S.; Monks, Brian G.; Fricke, Martin; Schmidt, Reinhold; Espevik, Terje; Jones, B; Jarnicki, Andrew G; Hansbro, Philip M; Busto, Patricia; Marshak-Rothstein, Ann; Hornemann, Simone; Aguzzi, Adriano; Kastenmüller, Wolfgang; Latz, Eicke. (2014) The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nature Immunology. volum 15 (8).
  Vitenskapelig artikkel
• Huber-Lang, Markus; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nilsson, Per; Nunn, Miles A.; Denk, Stephanie; Gaus, Wilhelm; Espevik, Terje; Mollnes, Tom Eirik. (2014) Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice. Journal of Immunology. volum 192 (11).
  Vitenskapelig artikkel
• Lappegård, Knut Tore; Garred, Peter; Jonasson, Lena; Espevik, Terje; Aukrust, Pål; Yndestad, Arne; Mollnes, Tom Eirik; Hovland, Anders. (2014) A vital role for complement in heart disease. Molecular Immunology. volum 61 (2).
  Vitenskapelig oversiktsartikkel/review
• Nordgård, Catherine Taylor; Nonstad, Unni; Olderøy, Magnus Østgård; Espevik, Terje; Draget, Kurt Ingar. (2014) Alterations in mucus barrier function and matrix structure induced by guluronate oligomers. Biomacromolecules. volum 15 (6).
  Vitenskapelig artikkel
• Nymo, Stig Haugset; Niyonzima, Nathalie; Espevik, Terje; Mollnes, Tom Eirik. (2014) Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF. Immunobiology. volum 219 (10).
  Vitenskapelig artikkel
• Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Bakke, Siril Skaret; Lappegård, Knut Tore; Brekke, Ole Lars; Lambris, John D.; Damås, Jan Kristian; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. (2014) Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. Journal of Immunology. volum 192 (6).
  Vitenskapelig artikkel
• Skjeflo, Espen Waage; Christiansen, Dorte; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2014) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by staphylococcus aureus in a human whole blood model. Journal of Immunology. volum 192 (6).
  Vitenskapelig artikkel
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Gustafsson, Björn; Torp, Sverre Helge; Espevik, Terje; Mollnes, Tom Eirik; Damås, Jan Kristian; Sandvik, Arne Kristian. (2014) Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease. Inflammatory Bowel Diseases. volum 20 (6).
  Vitenskapelig artikkel

2013

• Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Andersen, Jan Terje; Berntzen, Gøril; Pharo, Anne Margrethe; Lindstad, Julie Katrine; Ludviksen, Judith K; Brekke, Ole Lars; Barratt-Due, Andreas; Nielsen, Erik Waage; Stokes, Christopher R.; Espevik, Terje; Sandlie, Inger; Mollnes, Tom Eirik. (2013) Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation. Journal of Immunology. volum 191 (9).
  Vitenskapelig artikkel
• Espevik, Terje. (2013) CEMIR sitt forskningstema er inflammasjon.
  Nettsider (opplysningsmateriale)
• Espevik, Terje. (2013) CEMIR's research topic is inflammation.
  Nettsider (opplysningsmateriale)
• Espevik, Terje. (2013) Sensorer som setter i gang betennelse: hvordan virker de og hvorfor trenger vi dem?. Årbok / Det norske videnskaps-akademi.
  Populærvitenskapelig artikkel
• Granlund, Atle Van Beelen; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, Ignat; Gustafsson, Björn; Kidd, Mark; Beisvag, Vidar; Torp, Sverre Helge; Waldum, Helge; Martinsen, Tom Christian; Damås, Jan Kristian; Espevik, Terje; Sandvik, Arne Kristian. (2013) Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis. PLOS ONE. volum 8 (2).
  Vitenskapelig artikkel
• Grimstad, Øystein; Husebye, Harald; Espevik, Terje. (2013) TLR3 mediates release of IL-1 beta and cell death in keratinocytes in a caspase-4 dependent manner. Journal of dermatological science (Amsterdam). volum 72 (1).
  Vitenskapelig artikkel
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv. (2013) The medicinal mushroom Agaricus blazei Murill promotes NF-B activation via stimulation of TLR2 and inhibits its activation via TLR4. Journal of Pharmaceutical and Biomedical Sciences. volum 29.
  Vitenskapelig artikkel
• Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Inger; Nilsson, Per; Lambris, J; Nunn, Miles A.; Denk, Stephanie; Espevik, Terje; Huber-Lang, Markus. (2013) Double-blockade of CD14 and complement component C5 abolish the inflammatory storm and improve survival in mouse polymicrobial sepsis. Molecular Immunology. volum 56 (3).
  Sammendrag/abstract
• Nymo, Stig Haugset; Samstad, Eivind; Niyonzima, Nathalie; Aune, Marie Hjelmseth; Bergseth, Grete; Ryan, Liv; Brekke, Ole Lars; Latz, E; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. (2013) Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner. Molecular Immunology. volum 56 (3).
  Sammendrag/abstract
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje. (2013) The induction of cytokines by polycation containing microspheres by a complement dependent mechanism. Biomaterials. volum 34 (3).
  Vitenskapelig artikkel
• Rokstad, Anne Mari; Strand, Berit Løkensgard; Espevik, Terje; Mollnes, Tom Eirik. (2013) Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model. Micro and Nanosystems. volum 5 (3).
  Vitenskapelig artikkel
• Samstad, Eivind; Niyonzima, Nathalie; Nymo, Stig Haugset; Aune, Marie Hjelmseth; Ryan, Liv; Brekke, Ole Lars; Sandanger, I; Aukrust, Pål; Damås, Jan Kristian; Latz, Eicke; Lambris, J.D.; Mollnes, Tom Eirik; Espevik, Terje. (2013) Cholesterol crystals induce inflammasome activation and cytolcine release in a complement-dependent manner. Molecular Immunology. volum 56 (3).
  Sammendrag/abstract
• Sandanger, Øystein; Ranheim, Trine; Vinge, Leif Erik; Bliksøen, Marte; Alfsnes, Katrine; Finsen, Alexandra; Dahl, Christen Peder; Askevold, Erik Tandberg; Florholmen, Geir; Christensen, Geir Arve; Fitzgerald, Katherine A.; Lien, Egil; Valen, Guro; Espevik, Terje; Aukrust, Pål; Yndestad, Arne. (2013) The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovascular Research (CVR). volum 99 (1).
  Vitenskapelig artikkel
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Beisvag, Vidar; Waldum, Helge; Flo, Trude Helen; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2013) Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clinical and Experimental Immunology. volum 173 (3).
  Vitenskapelig artikkel
• Østvik, Ann Elisabet; Granlund, Atle; Bugge, Marit; Nilsen, Nadra; Torp, Sverre Helge; Waldum, Helge; Damås, Jan Kristian; Espevik, Terje; Sandvik, Arne Kristian. (2013) Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation. Inflammatory Bowel Diseases. volum 19 (2).
  Vitenskapelig artikkel

2012

• Nymo, Stig; Samstad, Eivind; Niyonzima, Nathalie; Bergseth, Grethe; Christiansen, Dorte; Ryan, Liv; Brekke, Ole Lars; Lappegard, Knut Tore; Damas, Jan Kristian; Latz, Eicke; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Complement dependency of cholesterol crystal-induced inflammation - I. Pathway activation mechanisms, cytokine responses and endothelial cell activation. Immunobiology. volum 217 (11).
  Sammendrag/abstract
• Barratt-Due, Andreas; Pischke, Søren Erik; Brekke, Ole Lars; Thorgersen, Ebbe Billmann; Nielsen, Erik Waage; Espevik, Terje; Huber-Lang, Markus; Mollnes, Tom Eirik. (2012) Bride and groom in systemic inflammation - The bells ring for complement and Toll in cooperation. Immunobiology. volum 217 (11).
  Vitenskapelig oversiktsartikkel/review
• Christiansen, Dorte; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, J.D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood. Advances in Experimental Medicine and Biology. volum 946.
  Vitenskapelig artikkel
• Christiansen, Dorte; Stenvik, Jørgen; Brekke, Ole Lars; Lambris, John D.; Espevik, Terje; Mollnes, Tom Eirik. (2012) Phagocytosis of Escherichia coli in human whole blood: Early complement dependency is succeeded by late CD14 dependency over time. Immunobiology. volum 217 (11).
  Sammendrag/abstract
• Doyle, SL; Husebye, Harald; Connolly, D; Espevik, Terje; O'Neill, LAJ; McGettrick, AF. (2012) The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nature Communications. volum 3.
  Vitenskapelig artikkel
• Granlund, Atle; Flatberg, Arnar; Østvik, Ann Elisabet; Drozdov, I; Gustafsson, Björn; Kidd, M; Beisvag, Vidar; Torp, Sverre Helge; Waldum, Helge; Martinsen, Tom Christian; Damås, Jan Kristian; Espevik, Terje; Sandvik, Arne Kristian. (2012) Dissecting the IBD Transcriptome. Inflammatory Bowel Diseases. volum 18.
  Sammendrag/abstract
• Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2012) Oligodeoxynucleotides inhibit Toll-like receptor 3 mediated cytotoxicity and CXCL8 release in keratinocytes. Experimental Dermatology. volum 21 (1).
  Vitenskapelig artikkel
• Klein, Dionne; Øvrebø, Kirsti Marie; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2012) Direct measurement of the interaction force between immunostimulatory CpG-DNA and TLR9 fusion protein. Journal of Molecular Recognition. volum 25 (2).
  Vitenskapelig artikkel
• Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Berntzen, Gøril; Stokes, Christopher R.; Espevik, Terje; Sandlie, Inger; Mollnes, Tom Eirik. (2012) Recombinant anti-human and anti-porcine CD14 antibodies. Immunobiology. volum 217 (11).
  Sammendrag/abstract
• Mollnes, Tom Eirik; Barratt-Due, Andreas; Pischke, Søren Erik; Sandanger, Øystein; Nunn, Miles A.; Espevik, Terje; Denk, Stephanie; Huber-Lang, Markus. (2012) The systemic inflammatory reaction in polymicrobial sepsis induced by murine cecal ligation and puncture is equally dependent on C5 and CD14. Immunobiology. volum 217 (11).
  Sammendrag/abstract
• Niyonzima, Nathalie; Samstad, Eivind; Aune, Marie Hjelmseth; Ryan, Liv; Damås, Jan Kristian; Wright, Samuel; Sandanger, Øystein; Aukrust, Pål; Latz, Eicke; Mollnes, Tom Eirik; Espevik, Terje. (2012) Complement dependency of cholesterol crystal-induced inflammation - II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP). Immunobiology. volum 217 (11).
  Sammendrag/abstract
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Lambris, John D.; Lacík, Igor; Mollnes, Tom Eirik; Espevik, Terje. (2012) Poly-cation containing alginate microcapsules induce cytokines by a complement-dependent mechanism. Immunobiology. volum 217 (11).
  Sammendrag/abstract
• Rokstad, Anne Mari; Gustafsson, Björn; Espevik, Terje; Bakke, Ingunn; Pfragner, Roswitha; Svejda, Bernhard; Modlin, Irvin M; Kidd, Mark. (2012) Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies. Cancer Science. volum 103 (7).
  Vitenskapelig artikkel
• Skjeflo, Espen; Christiansen, Dorte; Lambris, John D.; Espevik, Terje; Nielsen, Erik Waage; Mollnes, Tom Eirik. (2012) Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model. Immunobiology. volum 217 (11).
  Sammendrag/abstract
• Stenvik, Jørgen; Sletta, Håvard; Grimstad, Øystein; Pukstad, Brita; Ryan, Liv; Aune, Randi; Strand, Wenche Iren; Tøndervik, Anne; Torp, Sverre Helge; Skjåk-Bræk, Gudmund; Espevik, Terje. (2012) Alginates induce differentiation and expression of CXCR7 and CXCL12/SDF-1 in human keratinocytes - the role of calcium. Journal of Biomedical Materials Research. Part A. volum 100A (10).
  Vitenskapelig artikkel
• Østvik, Ann Elisabet; Granlund, Atle Van Beelen; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2012) Induction of Lipocalin-2 in Colonic Epithelial Cells in Inflammatory Bowel Disease. Inflammatory Bowel Diseases. volum 18.
  Sammendrag/abstract
• Østvik, Ann Elisabet; Nilsen, Nadra; Granlund, Atle; Torp, Sverre Helge; Flatberg, Arnar; Waldum, Helge; Espevik, Terje; Damås, Jan Kristian; Sandvik, Arne Kristian. (2012) Enhanced expression of CXCL10 in inflammatory bowel disease-role of mucosal TLR3 stimulation. Journal of Crohn’s and Coltis Supplements. volum 6.
  Sammendrag/abstract

2011

• Grimstad, Øystein; Sandanger, Øystein; Ryan, Liv; Otterdal, Kari; Damås, Jan Kristian; Pukstad, Brita; Espevik, Terje. (2011) Cellular sources and inducers of cytokines present in acute wound fluid. Wound Repair and Regeneration. volum 19 (3).
  Vitenskapelig artikkel
• Nørgaard, Nikolai Nordberg; Holien, Toril; Jönsson, S; Hella, Hanne; Espevik, Terje; Sundan, Anders; Standal, Therese. (2011) CpG-ODN inhibits Smad-dependent BMP signaling; Effects on myeloma cell apoptosis and in vitro osteoblastogenesis. Bone. volum 48 (1).
  Sammendrag/abstract
• Rokstad, Anne Mari; Brekke, Ole Lars; Steinkjer, Bjørg; Ryan, Liv; Kolláriková, Gabriela; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Lacík, Igor; Espevik, Terje; Mollnes, Tom Eirik. (2011) Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomaterialia. volum 7 (6).
  Vitenskapelig artikkel
• Torgersen, Maria Lyngaas; Engedal, Kim Nikolai; Pedersen, Anne-Mari Gjestvang; Husebye, Harald; Espevik, Terje; Sandvig, Kirsten. (2011) Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunology and Medical Microbiology. volum 61 (1).
  Vitenskapelig artikkel

2010

• Duewell, P; Kono, H; Rayner, KJ; Sirois, CM; Vladimer, G; Bauernfeind, FG; Abela, GS; Franchi, L; Nunez, G; Schnurr, M; Espevik, Terje; Lien, E; Fitzgerald, KA; Rock, KL; Moore, KJ; Wright, SD; Hornung, V; Latz, Eicke. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. volum 464 (7293).
  Vitenskapelig artikkel
• Christiansen, D; Brekke, Ole Lars; Stenvik, Jørgen; Lambris, JD; Espevik, Terje; Mollnes, Tom Eirik. (2010) Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood. Molecular Immunology. volum 47 (13).
  Sammendrag/abstract
• Etokebe, GE; Skjeldal, F; Nilsen, Nadra; Rodionov, Dmitrii; Knezevic, Jelena; Bulat-Kardum, Ljiljana; Espevik, Terje; Bakke, Oddmund; Dembic, Zlatko. (2010) Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele. Scandinavian Journal of Immunology. volum 71 (5).
  Vitenskapelig artikkel
• Grimstad, Øystein; Pukstad, Brita; Stenvik, Jørgen; Espevik, Terje. (2010) TLR3 mediated cytotoxicity in keratinocytes is inhibited by co-stimulation with oligodeoxynucleotides. Journal of Investigative Dermatology. volum 130.
  Sammendrag/abstract
• Halaas, Øyvind; Steigedal, Magnus; Haug, Markus; Awuh, Jane Atesoh; Ryan, Liv; Brech, Andreas; Sato, S; Husebye, Harald; Cangelosi, Gerard; Akira, Shizuo; Strong, Roland; Espevik, Terje; Flo, Trude Helen. (2010) Intracellular Mycobacterium avium Intersect Transferrin in the Rab11(+) Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway. Journal of Infectious Diseases. volum 201 (5).
  Vitenskapelig artikkel
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil; Kvalheim, Gunnar. (2010) The Medicinal and Antitumor Mushroom, Agaricus Blazei Murill, Activates NF-kappa B Via TLR2 but Not TLR4 In Monocytic Cells, and Stimulates Monocyte-Derived Dendritic Cells (MDDC) to Increased Cell Surface Marker Expression and Cytokine Production, and May Thus Have Adjuvant Effect In MDDC Cancer Vaccines. Blood. volum 116 (21).
  Sammendrag/abstract
• Hetland, Geir; Tryggestad, Anne Merete Aaland; Espevik, Terje; Ryan, Liv; Tangen, Jon-Magnus; Johnson, Egil; Kvalheim, Gunnar. (2010) The medicinal and antitumour mushroom, agaricus blazei murill, activates NF-KB via TLR2 in monocytic cells and induces expression of cell surface markers and production of cytokines in human monocyte-derived dendritic cells (MDDC) in vitro. European Journal of Cancer. volum 8 (5).
  Sammendrag/abstract
• Husebye, Harald; Aune, Marie Hjelmseth; Stenvik, Jørgen; Samstad, Eivind Ottersen; Skjeldal, Frode Miltzow; Halaas, Øyvind; Nilsen, Nadra; Stenmark, Harald Alfred; Latz, Eicke; Lien, Egil; Mollnes, Tom Eirik; Bakke, Oddmund; Espevik, Terje. (2010) The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes. Immunity. volum 33 (4).
  Vitenskapelig artikkel
• Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2010) Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy. Ultramicroscopy. volum 110 (6).
  Vitenskapelig artikkel
• Nilsen, Asbjørn Magne; Vik, Randi; Behrens, Carl; Drabløs, Per Arne; Espevik, Terje. (2010) Beryllium Sensitivity Among Workers at a Norwegian Aluminum Smelter. American Journal of Industrial Medicine. volum 53 (7).
  Vitenskapelig artikkel
• Nørgaard, Nikolai Nordberg; Holien, Toril; Jonsson, Sofia; Hella, Hanne; Espevik, Terje; Sundan, Anders; Standal, Therese. (2010) CpG-Oligodeoxynucleotide Inhibits Smad-Dependent Bone Morphogenetic Protein Signaling: Effects on Myeloma Cell Apoptosis and In Vitro Osteoblastogenesis. Journal of Immunology. volum 185 (6).
  Vitenskapelig artikkel
• Pukstad, Brita; Ryan, Liv; Flo, Trude Helen; Stenvik, Jørgen; Moseley, Ryan; Harding, Keith; Thomas, David W.; Espevik, Terje. (2010) Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. Journal of dermatological science (Amsterdam). volum 59 (2).
  Vitenskapelig artikkel
• Salvesen, Bodil; Stenvik, Jørgen; Rosetti, Carlo; Saugstad, Ola D; Espevik, Terje; Mollnes, Tom E.. (2010) Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner. Molecular Immunology. volum 47 (6).
  Vitenskapelig artikkel

2009

• Damås, Jan Kristian; Davi, Giovanni; Jensenius, M; Santilli, F; Otterdal, K; Ueland, T; Flo, Trude Helen; Lien, E; Espevik, Terje; Frøland, Stig S; Vitale, G; Raoult, D; Aukrust, P. (2009) Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever. Journal of Infection. volum 58 (1).
  Vitenskapelig artikkel
• Castellheim, A; Brekke, Ole Lars; Espevik, T; Harboe, M; Harboe, M; Mollnes, Tom Eirik. (2009) Innate Immune Responses to Danger Signals in Systemic Inflammatory Response Syndrome and Sepsis. Scandinavian Journal of Immunology. volum 69 (6).
  Vitenskapelig oversiktsartikkel/review
• Espevik, Terje; Rokstad, Anne Mari; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund. (2009) Mechanisms of the host immune response to alginate microcapsules. The Bioartificial Pancreas and Other Biohybrid Therapies.
  Faglig kapittel
• Iversen, Ann-Charlotte; Steinkjer, Bjørg; Nilsen, Nadra; Bohnhorst, Janne Øvrebø; Moen, Siv Helen; Vik, Randi; Stephens, Phil; Thomas, DW; Benedict, Chris A.; Espevik, Terje. (2009) A proviral role for CpG in cytomegalovirus infection. Journal of Immunology. volum 182 (9).
  Vitenskapelig artikkel
• Palsson-McDermott, EM; Doyle, SL; McGettrick, AF; Hardy, M; Husebye, Harald; Banahan, K; Gong, M; Golenbock, D; Espevik, Terje; O'Neill, LAJ. (2009) TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nature Immunology. volum 10 (6).
  Vitenskapelig artikkel
• Sandanger, O; Sandanger, Øystein; Ryan, Liv; Bohnhorst, Janne Øvrebø; Iversen, AC; Iversen, Ann-Charlotte; Husebye, Harald; Halaas, O; Halaas, Øyvind; Landrø, Linn; Aukrust, Pål; Frøland, Stig S.; Elson, Greg; Visintin, Alberto; Øktedalen, Olav; Damås, Jan Kristian; Damas, JK; Sundan, Anders; Golenbock, Douglas T.; Espevik, Terje. (2009) IL-10 Enhances MD-2 and CD14 Expression in Monocytes and the Proteins Are Increased and Correlated in HIV-Infected Patients. Journal of Immunology. volum 182 (1).
  Vitenskapelig artikkel
• Standal, Therese; Norgaard, NN; Bohnhorst, J; Espevik, T; Waage, A; Sundan, A. (2009) Does Toll-like Receptor 9 Signaling Play a Role in Myeloma Disease Progression?. Clinical Lymphoma & Myeloma. volum 9.
  Sammendrag/abstract
• Yndestad, A; Landrø, Linn; Ueland, Thor; Dahl, CP; Flo, Trude Helen; Vinge, Leif Erik; Espevik, Terje; Frøland, Stig S; Husberg, Cathrine; Christensen, Geir; Dickstein, K; Kjekshus, John; Øie, Erik; Gullestad, Lars; Aukrust, Pål. (2009) Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. European Heart Journal. volum 30 (10).
  Vitenskapelig artikkel

2008

• Halaas, Øyvind; Husebye, Harald; Stenmark, Harald; Espevik, Terje. (2008) Intracellular Trafficing of Toll-like Receptors. Signalling by Toll-like Receptors.
  Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
• Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, JD; Mollnes, TE; Brandtzæg, Petter. (2008) Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity. volum 76 (9).
  Vitenskapelig artikkel
• Hellerud, BC; Stenvik, Jørgen; Espevik, Terje; Lambris, John D.; Mollnes, Tom Eirik; Brandtzaeg, P. (2008) Stages of meningococcal sepsis stimulated in vitro, with emphasis on complement and Toll-like receptor activation. Infection and Immunity. volum 76 (9).
  Vitenskapelig artikkel
• Hetland, G; Tryggestad, AMA; Forland, T; Johnson, E; Ryan, L; Espevik, Terje. (2008) Proposed immunomodulatory co-therapy for hematological cancer by the medicinal mushroom Agaricus blazei Murill, is facilitated by its stimulation of TLR2 and activation of NF-KB. Vox Sanguinis. volum 95.
  Sammendrag/abstract
• Klein, Dionne C.G.; Latz, Eicke; Espevik, Terje; Stokke, Bjørn Torger. (2008) Effects of CpG-DNA on Toll-like receptor 9 studied by AFM. TRAUNER Verlag. 2008. ISBN 978-3-85499-400-8.
  Vitenskapelig antologi/Konferanseserie
• Landrø, Linn Aina Ysland; Landro, L; Damås, Jan Kristian; Damas, JK; Flo, Trude Helen; Heggelund, L; Ueland, T; Tjonnfjord, GE; Tjønnfjord, Geir Erland; Espevik, Terje; Aukrust, P; Frøland, Stig Sophus; Froland, SS. (2008) Decreased serum lipocalin-2 levels in human immunodeficiency virus-infected patients: increase during highly active anti-retroviral therapy. Clinical and Experimental Immunology. volum 152 (1).
  Vitenskapelig artikkel
• Mollnes, Tom Eirik; Christiansen, D; Brekke, Ole Lars; Espevik, T. (2008) Hypothesis: Combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response. Advances in Experimental Medicine and Biology. volum 632.
  Vitenskapelig artikkel
• Nilsen, Nadra; Deininger, S; Nonstad, Unni; Skjeldal, F; Husebye, Harald; Rodionov, D; von Aulock, S; Hartung, T; Lien, E; Lien, E; Bakke, O; Espevik, Terje. (2008) Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36. Journal of Leukocyte Biology. volum 84.
  Vitenskapelig artikkel

2007

• Halaas, Øyvind; Husebye, Harald; Espevik, Terje. (2007) The journey of Toll-like receptors in the cell. Advances in Experimental Medicine and Biology. volum 598.
  Vitenskapelig artikkel
• Latz, E; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, CM; Klein, Dionne; Monks, BG; Mcknight, C. james; Duprex, W. paul; Espevik, Terje; Golenbock, DT. (2007) Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9. International Immunology. volum 8 (11).
  Vitenskapelig artikkel
• Latz, Eicke; Verma, Anjali; Visintin, A; Gong, Mei; Sirois, Cherilyn m.; Klein, Dionne; Monks, Brian G.; Mcknight, C. james; Lamphier, Marc s.; Duprex, W. paul; Espevik, Terje; Golenbock, Douglas T.. (2007) Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nature Immunology. volum 8 (7).
  Vitenskapelig artikkel
• Tunheim, G; Thompson, KM; Fredriksen, AB; Espevik, Terje; Schjetne, KW; Bogen, B. (2007) Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates. Vaccine. volum 25 (24).
  Vitenskapelig artikkel

2006

• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) BeLPT testing Karmøy. Undervegsrapport 1. Januar 2006. 2006.
  Rapport
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 2. Februar 2006. 2006.
  Rapport
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 3. Mars 2006. 2006.
  Rapport
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing Karmøy. Undervegsrapport 4. April 2006. 2006.
  Rapport
• Nilsen, Asbjørn Magne; Vik, Randi; Espevik, Terje. (2006) Be-LPT testing at Hydro Aluminium Karmøy AS. Final Report. June 2006. 2006.
  Rapport
• Bohnhorst, Janne Øvrebø; Rasmussen, T; Moen, Siv H; Fløttum, Marianne; Knudsen, L; Børset, Magne; Espevik, Terje; Sundan, Anders. (2006) Toll-like receptors mediate proliferation and survival of multiple myeloma cells. Leukemia. volum 20.
  Vitenskapelig artikkel
• Espevik, Terje; Lien, Egil. (2006) Vaksine mot svartedauen. Gemini.
  Populærvitenskapelig artikkel
• Espevik, Terje; Skjåk-Bræk, Gudmund. (2006) Friskere fisk med tang og tare. Gemini.
  Populærvitenskapelig artikkel
• Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B; Brech, A; Latz, Eicke; Espevik, Terje. (2006) Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO Journal. volum 25.
  Vitenskapelig artikkel
• Johnsen, Ingvild Bjellmo; Nguyen, Thank Thuy Thi; Ringdal, Monika; Tryggestad, AM; Bakke, Oddmund; Lien, Egil; Espevik, Terje; Anthonsen, Marit Walbye. (2006) Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. EMBO Journal. volum 26 (25).
  Vitenskapelig artikkel
• Rokstad, Anne Mari Aukan; Donati, Ivan; Borgogna, Massimiliano; Oberholzer, José; Strand, Berit Løkensgard; Espevik, Terje; Skjåk-Bræk, Gudmund. (2006) Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials. volum 27.
  Vitenskapelig artikkel
• Ueland, Thor; Espevik, Terje; Kjekshus, John; Gullestad, Lars; Omland, Torbjørn; Squire, Iain B.; Frøland, Stig S.; Froland, Stig S; Mollnes, Tom Eirik; Dickstein, Kenneth; Aukrust, Pål. (2006) Mannose binding lectin and soluble Toll-lilke receptor 2 in heart failure following acute myocardial infarction. Journal of Cardiac Failure. volum 12 (8).
  Vitenskapelig artikkel

2005

• Heggelund, Lars; Mollnes, Tom Eirik; Espevik, Terje; Muller, Fredrik; Kristiansen, Knut Ivan; Aukrust, Pål; Frøland, Stig Sophus. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection. European Journal of Clinical Investigation. volum 35.
  Vitenskapelig artikkel
• Mancuso, Guiseppe; Midiri, A; Biondo, Carmelo; Beninati, C.; Gambuzza, M; Macri, D; Bellantoni, A; Weintraub, A; Espevik, Terje; Teti, Guiseppe. (2005) Bacteroides fragilis-derived lipopolysaccharide produces cell activation and lethal toxicity via toll-like receptor 4. Infection and Immunity. volum 73 (9).
  Vitenskapelig artikkel
• Rokstad, Anne Mari Aukan; Bjerkvig, Rolf; Espevik, Terje; Lund-Johansen, M. (2005) Applications of Cell Immobilisation Biotechnology, Focus on Biotechnology. Book chapter: Cell encapsulation therapy for malignant gliomas. Springer. 2005. ISBN 1-4020-3229-3.
  Vitenskapelig antologi/Konferanseserie
• Dybdahl, Brit; Slørdahl, Stig Arild; Waage, Anders; Kierulf, Peter; Espevik, Terje; Sundan, Anders. (2005) Myocardial ischaemia and the inflammatory response: release of heat shock protein 70 after myocardial infarction. Heart. volum 91 (3).
  Vitenskapelig artikkel
• Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P; Froland, SS. (2005) Modulatory effect of mannose-binding lectin on cytokine resposes: possible roles in HIV infection. European Journal of Clinical Investigation. volum 35 (12).
  Vitenskapelig artikkel
• Heggelund, L; Mollnes, TE; Espevik, Terje; Muller, F; Kristiansen, KI; Aukrust, P; Frøland, Stig S. (2005) Modulatory effect of mannose-binding lectin on cytokine responses: roles in HIV infection. European Journal of Clinical Investigation. volum 35.
  Vitenskapelig artikkel
• Manukyan, M; Triantafilou, K; Triantafilou, M; Mackie, A; Nilsen, Nadra Jesmine; Espevik, Terje; Wiesmullers, KH; Ulmer, AJ; Heine, H. (2005) Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1. European Journal of Immunology. volum 35 (3).
  Vitenskapelig artikkel

2004

• Dybdahl, Brit; Wahba, Alexander; Haaverstad, R; Kirkeby-Garstad, Idar; Kierulf, Peter; Espevik, Terje; Sundan, Anders. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery. volum 25.
  Vitenskapelig artikkel
• Dybdahl, Brit; Wahba, Alexander; Haaverstad, Rune; Kirkeby-Garstad, I.; Kierulf, P; Espevik, Terje; Sundan, A. (2004) On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. European Journal of Cardio-Thoracic Surgery. volum 25.
  Vitenskapelig artikkel
• Espevik, Terje. (2004) Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1. Journal of Immunology. volum 15 (4).
  Vitenskapelig artikkel
• Heggelund, L; Flo, Trude Helen; Berg, K.; Lien, E; Espevik, Terje. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London). volum 3 (18).
  Vitenskapelig artikkel
• Heggelund, L; Muller, F; Lien, E; Yndestad, A; Ueland, T; Kristiansen, KI; Espevik, Terje; Aukrust, P; Frøland, Stig Sophus; Froland, SS. (2004) Increased expression of Toll-like receptor 2 on monocytes in HIV infection: Possible roles in inflammation and viral replication. Clinical Infectious Diseases. volum 39.
  Vitenskapelig artikkel
• Heggelund, Lars; Flo, T; Berg, K; Lien, T; Mollnes, TE; Ueland, Thor; Aukrust, Pål; Espevik, T; Frøland, Stig Sophus. (2004) Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (London). volum 18.
  Vitenskapelig artikkel
• Liabakk, Nina-Beate; Espevik, Terje. (2004) Monoclonal antibodies against TRAIL. Vitamines and Hormones.
  Vitenskapelig artikkel
• Frantisek, S; Latz, E; Re, F; Mandell, L; Repik, G; Golenbock, D; Espevik, Terje; Kurt-Jones, E; Finberg, R. (2004) Importance of extra-and intracellular domains of TLR1 and TLR2 receptors in NF-kappa B signaling. Tissue Antigens. volum 64.
  Sammendrag/abstract
• Halaas, Øyvind; Liabakk, Nina-Beate; Vik, Randi; Beninati, C; Henneke, P; Sundan, Anders; Espevik, Terje. (2004) Monocytes stimulated with group B Streptococci or interferons release tumour necrosis factor-related apoptosis-inducing ligand. Scandinavian Journal of Immunology. volum 60 (1-2).
  Vitenskapelig artikkel
• Heggelund, L; Damas, JK; Damås, Jan Kristian; Yndestad, A; Holm, AM; Muller, F; Lien, E; Lien, E; Espevik, Terje; Aukrust, P; Froland, SS; Frøland, Stig Sophus. (2004) Stimulation of toll-like receptor 2 in mononuclear cells from HIV-infected patients induces chemokine responses: possible pathogenic consequences. Clinical and Experimental Immunology. volum 138 (1).
  Vitenskapelig artikkel
• Latz, E; Schoenemeyer, A; Visintin, A; Fitzgerald, KA; Monks, BG; Knetter, Cathrine; Lien, E; Nilsen, Nadra; Espevik, Terje; Golenbock, DT. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nature Immunology. volum 5.
  Vitenskapelig artikkel
• Latz, E; Visintin, A; Espevik, Terje; Golenbock, DT. (2004) Mechanisms of TLR9 activation. Journal of Endotoxin Research. volum 10 (6).
  Vitenskapelig artikkel
• Nilsen, N; Nonstad, U; Khan, N; Knetter, Cathrine; Akira, S; Sundan, Anders; Espevik, Terje; Lien, E. (2004) Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88. Journal of Biological Chemistry. volum 279.
  Vitenskapelig artikkel
• Nilsen, Nadra; Nonstad, Unni; Kahn, Naseema; Knetter, Cathrine; Akira, Shizuo; Sundan, Anders; Espevik, Terje; Lien, Egil. (2004) Lipopolysaccharide and Double-stranded RNA Up-regulate Toll-like Receptor 2 Independently of Myeloid Differentiation Factor 88. Journal of Biological Chemistry.
  Vitenskapelig artikkel

2003

• Adib-Conquy, M; Moine, P; Asehnoune, K; Edouard, A; Espevik, Terje; Miyake, K; Werts, C; Cavaillon, J-M. (2003) Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. American Journal of Respiratory and Critical Care Medicine. volum 168 (2).
  Vitenskapelig artikkel
• Espevik, Terje; Latz, Eicke; Lien, Egil; Monks, Brian G.. (2003) Cell distribution and functions of Toll-like receptor 4 studied by fluorescent gene constructs. Scandinavian Journal of Infectious Diseases. volum 35 (9).
  Vitenskapelig artikkel
• Latz, E; Visintin, A; Lien, E; Fitzgerald, KA; Espevik, Terje; Golenbock, DT. (2003) The LPS receptor generates inflammatory signals from the cell surface. Journal of Endotoxin Research. volum 9.
  Vitenskapelig artikkel
• Mori, Y; Yoshimura, A; Ukai, T; Lien, Egil; Espevik, Terje; Hara, Y. (2003) Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis. Oral Microbiology and Immunology. volum 18 (1).
  Vitenskapelig artikkel
• Rokstad, Anne Mari Aukan; Strand, Berit Løkensgard; Rian, K.; Steinkjer, Bjørg; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (2003) Evaluation of different types of alginate microcapsules as bioreactors for producing endostatin. Cell Transplantation. volum 12.
  Vitenskapelig artikkel
• Sandor, F; Latz, Eicke; Mandell, L; Repik, G; Golenbock, Douglas T.; Espevik, Terje; Kurt-Jones, EA; Finberg, RW. (2003) Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling. Journal of Cell Biology. volum 162 (6).
  Vitenskapelig artikkel
• Schjetne, KW; Thompson, Keith; Fleckenstein, Burkhard; Aarvak, Tanja; Flo, T. H.; Iversen, Jens Gustav; Espevik, T; Bogen, Bjarne. (2003) Cutting edge: Link between innate and adaptive immunity: toll like receptor 2 (TLR 2) captures antigen for MHC class II presentation to CD4+ T cell responses. Journal of Immunology. volum 171.
  Vitenskapelig artikkel
• Schjetne, KW; Thompson, KM; Nilsen, Nadra; Flo, Trude Helen; Fleckenstein, B; Iversen, JG; Espevik, Terje; Bogen, B. (2003) Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. Journal of Immunology. volum 171 (1).
  Vitenskapelig artikkel
• Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy. Biotechnology and Bioengineering. volum 82 (4).
  Vitenskapelig artikkel
• Strand, Berit Løkensgard; Mørch, Yrr Asbjørg; Syvertsen, Kjersti R.; Espevik, Terje; Skjåk-Bræk, Gudmund. (2003) Microcapsules made by enzymatically tailored alginate. Journal of Biomedical Materials Research. volum 64 (3).
  Vitenskapelig artikkel
• Visintin, A; Latz, Eicke; Monks, Brian G.; Espevik, Terje; Golenbock, Douglas T.. (2003) Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. Journal of Biological Chemistry. volum 278 (48).
  Vitenskapelig artikkel

2002

• Belge, KU; Dayyani, F; Horelt, A; Siedlar, M; Frankenberger, M; Frankenberger, B; Espevik, Terje; Ziegler-Heitbrock, L. (2002) The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF. Journal of Immunology. volum 168 (7).
  Vitenskapelig artikkel
• Dybdahl, Brit; Lien, Egil; Flo, Trude Helen; Espevik, Terje; Sundan, Anders; Wahba, Alexander; Sellevold, Olav F Münter. (2002) Heat Shock Proteins and Endotoxin Combined as a Trigger for Inflammatory Cytokine Release During Cardiopulmonary Bypass: A Possible Third Way? Letter til artikkel. Circulation. volum 106.
  Vitenskapelig artikkel
• Dybdahl, Brit; Wahba, Alexander; Lien, Egil; Flo, Trude Helen; Waage, Anders; Sellevold, Olav F Münter; Espevik, Terje; Sundan, Anders; Qureshi, Nilofer. (2002) Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation. volum 105 (6).
  Vitenskapelig artikkel
• Ellingsen, E.A.; Morath, S; Flo, Trude Helen; Schromm, Andra; Hartung, T; Thiemermann, C; Espevik, Terje; Golenbock, Douglas T.; Foster, D; Solberg, R.; Aasen, A; Wang, J. (2002) Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. Medical Science Monitor. volum 8 (5).
  Vitenskapelig artikkel
• Espevik, Terje. (2002) På väg att knäcka hjärntumörer. Länstidningen, Østersund, Sverige.
  Kronikk
• Flo, Trude Helen; Ryan, Liv; Latz, Eicke; Takeuchi, Osamu; Monks, Brian G.; Lien, Egil; Halaas, Øyvind; Akira, Shizuo; Skjåk-Bræk, Gudmund; Golenbock, Douglas T.; Espevik, Terje. (2002) Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. Journal of Biological Chemistry. volum 277 (38).
  Vitenskapelig artikkel
• Latz, Eicke; Visintin, A; Lien, Egil; Fitzgerald, KA; Monks, Brian G.; Kurt-Jones, EA; Golenbock, Douglas T.; Espevik, Terje. (2002) Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. Journal of Biological Chemistry. volum 277 (49).
  Vitenskapelig artikkel
• Rokstad, Anne Mari Aukan; Holtan, Synnøve; Strand, Berit Løkensgard; Steinkjer, Bjørg; Ryan, Liv; Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Espevik, Terje. (2002) Microencapsulation of cells producing therapeutic proteins: Optimizing cell growth and secretion. Cell Transplantation. volum 11.
  Vitenskapelig artikkel
• Strand, Berit Løkensgard; Gåserød, Olav; Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (2002) Alginate-polylysine-alginate microcapsules – effect of size reduction on capsule properties. Journal of Microencapsulation. volum 19.
  Vitenskapelig artikkel
• Tamai, Riyoko; Sakuta, T; Matsushita, K; Torii, M; Takeuchi, Osamu; Akira, Shizuo; Akashi, Sachiko; Espevik, Terje; Sugawara, Shunji; Takada, Haruhiko. (2002) Human gingival CD14(+) fibroblasts primed with gamma interferon increase production of interleukin-8 in response to lipopolysaccharide through up-regulation of membrane CD14 and MyD88 mRNA expression. Infection and Immunity. volum 70 (3).
  Vitenskapelig artikkel
• van der Kleij, D; Latz, Eicke; Brouwers, JF; Kruize, YC; Schmitz, M; Kurt-Jones, EA; Espevik, Terje; de Jong, EC; Kapsenberg, ML; Golenbock, Douglas T.; Tielens, AG; Yazdanbakhsh, M. (2002) A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates Toll-like recepytor 2 and affects immune polarization. Journal of Biological Chemistry. volum 277 (50).
  Vitenskapelig artikkel
• Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig Sophus; Espevik, Terje. (2002) Development, characterization and use of monoclonal antibodies against sTRAIL measurement of sTRAIL by ELISA. JIM - Journal of Immunological Methods. volum 259.
  Vitenskapelig artikkel

2001

• Flo, Trude Helen; Halaas, Øyvind; Torp, Sverre Helge; Ryan, Liv; Lien, Egil; Dybdahl, Brit; Sundan, Anders; Espevik, Terje. (2001) Differential expression of Toll-like receptor 2 in human cells. Journal of Leukocyte Biology. volum 69.
  Vitenskapelig artikkel
• Flo, Trude Helen; Ryan, Liv; Kilaas, L; Skjåk-Bræk, Gudmund; Ingalls, Robin; Sundan, Anders; Golenbock, D; Espevik, Terje. (2001) The involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity. volum 68.
  Vitenskapelig artikkel
• Henneke, Philipp; Takeuchi, Osamu; van Strijp, JA; Guttormsen, HK; Smith, JA; Schromm, Andra; Espevik, Terje; et, al.. (2001) Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. Journal of Immunology. volum 167 (12).
  Vitenskapelig artikkel
• Liabakk, Nina-Beate; Sundan, Anders; Torp, Sverre Helge; Aukrust, Pål; Frøland, Stig; Espevik, Terje. (2001) Development, characterization and use of monclonal antibodies against Strail: Measurement of Strail by Elisa. JIM - Journal of Immunological Methods. volum 259/1-2.
  Vitenskapelig artikkel
• Lien, Egil; Chow, Jesse C.; Hawkins, Lynn D.; McGuinness, Pamela D.; Miyake, Kensuke; Espevik, Terje; Gusovsky, Fabian; Golenbock, Douglas T.. (2001) A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway. Journal of Biological Chemistry.
  Vitenskapelig artikkel
• Rokstad, Anne Mari Aukan; Kulseng, Bård Eirik; Strand, Berit Løkensgard; Skjåk-Bræk, Gudmund; Espevik, Terje. (2001) Transplantation of alginate microcapsules with proliferating cells in mice. Capsular overgrowth and suvival of encapsulated cells of mice and human origin. Annals of the New York Academy of Sciences. volum 944.
  Vitenskapelig artikkel
• Strand, Berit Løkensgard; Ryan, Liv; Int Veld, Peter; Kulseng, Bård Eirik; Rokstad, Anne Mari Aukan; Skjåk-Bræk, Gudmund; Espevik, Terje. (2001) Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines. Cell Transplantation. volum 10.
  Vitenskapelig artikkel
• Sugawara, Shunji; Yang, Shuhua; Iki, Koichi; Hatakeyama, Junko; Tamai, Riyoko; Takeuchi, Osamu; Akashi, Sachiko; Espevik, Terje; Akira, Shizuo; Takada, Haruhiko. (2001) Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by Toll-like receptor 2. Infection and Immunity. volum 69 (8).
  Vitenskapelig artikkel
• Wang, J; Warris, A; Ellingsen, E.A.; Jorgensen, P.F.; Flo, Trude Helen; Espevik, Terje; Solberg, R.; Verweij, P.E.; Aasen, A. O.. (2001) Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infection and Immunity. volum 69 (4).
  Vitenskapelig artikkel
• Iversen, Ann-Charlotte; Sundan, Anders; Espevik, Terje. (2001) IFN-alpha(2b) and IFN-beta induce TRAIL-mediated NK cell cytotoxicity. The FASEB Journal. volum 15.
  Sammendrag/abstract
• Jenssen, Jon A; Espevik, Terje. (2001) Cellebiologisk metode for å påvise biologisk aktivitet av svevestøv. 2001. ISBN 8214024242. SINTEF Rapport.
  Rapport
• Liabakk, Nina-Beate; Waage, Anders; Lien, Egil; Stenvik, Jørgen; Espevik, Terje. (2001) Cytokine bioassays. Methods in Molecular Medicine. volum 67.
  Vitenskapelig artikkel

2000

• Cuzzola, M.; Mancuso, G.; Beninati, C.; Biondo, C.; Genovese, F.; Tomasello, F.; Flo, Trude Helen; Espevik, Terje; Teti, G.. (2000) _B2 integrins are involved in cytokine responses to whole gram-positive bacteria. Journal of Immunology. volum 164.
  Vitenskapelig artikkel
• Cuzzola, Maria; Mancuso, Guiseppe; Beninati, Concetta; Biondo, Carmelo; von Hunolstein, Christina; Orefici, Graziella; Espevik, Terje; Flo, Trude Helen; Teti, Guisseppe. (2000) Human monocyte receptors involved in tumor necrosis factor responses to group B streptococcal products. Infection and Immunity. volum 68.
  Vitenskapelig artikkel
• Espevik, Terje; Waage, Anders; Sundan, A.. (2000) Summary of the 8 th International TNF Congress. Trondheim. 2000.
  Fagbok
• Espevik, Terje; Waage, Anders; Sundan, Anders. (2000) Summary of the 8th International TNF Congress, Trondheim, May 14-18, 2000. 2000. NBS-nytt.
  Rapport
• Falch, Berit H.; Espevik, Terje; Ryan, Liv; Stokke, Bjørn Torger. (2000) The cytokine stimulating activity of (1->3)-_B-D-glucans is dependent on the triple helix conformation. Carbohydrate Research. volum 329.
  Vitenskapelig artikkel
• Flo, T.H.; Ryan, L.; Kilaas, L.; Skjåk-Bræk, Gudmund; Ingalls, R.R.; Sundan, A.; Golenbock, D.T.; Espevik, Terje. (2000) Involvement of CD14 and beta2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity. volum 68 (12).
  Vitenskapelig artikkel
• Flo, Trude Helen; Halaas, Øyvind; Lien, Egil; Ryan, Liv; Teti, Guiseppe; Golenbock, Douglas T.; Sundan, Anders; Espevik, Terje. (2000) Human Toll-like Receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. Journal of Immunology. volum 164.
  Vitenskapelig artikkel
• Flo, Trude Helen; Ryan, Liv; Kilaas, Lars; Skjåk-Bræk, Gudmund; Ingalls, Robin R.A; Sundan, Anders; Golenbock, Douglas T.; Espevik, Terje. (2000) Involvement of CD14 and _B2-integrins in activating cells with soluble and particulate lipopolysaccharides and mannuronic acid polymers. Infection and Immunity. volum 68 (12).
  Vitenskapelig artikkel
• Lien, E.; Espevik, Terje. (2000) Toll-lignende reseptorer - kroppens sensorer for infeksjon. NBS-nytt.
  Populærvitenskapelig artikkel
• Skjåk-Bræk, Gudmund; Flo, Trude Helen; Halaas, Øyvind; Espevik, Terje. (2000) Immune stimulating properties of di-equatorially beta(1->4) linked poly-uronides. Proceedings of the Phytochemical Society of Europe. volum 44.
  Vitenskapelig artikkel

1999

• Aukrust, Pål; Haug, Charlotte J.; Ueland, Thor; Lien, Egil; Muller, Fredrik; Espevik, T; Bollerslev, Jens; Frøland, Stig Sophus. (1999) Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: indication of normalization of the bone-remodeling process during highly active antiretroviral therapy. Journal of Clinical Endocrinology and Metabolism (JCEM). volum 84 (1).
  Vitenskapelig artikkel
• Aukrust, Pål; Haug, Charlotte J.; Ueland, Thor; Lien, Egil; Müller, Fredrik; Espevik, Terje; Bollerslev, Jens; Frøland, Stig S.. (1999) Decreased bone formative and enhanced resorptive markers in human immunodeficiency virus infection: Indication of normalization of the bone-remodeling process during highly active antiretroviral therapy. Journal of Clinical Endocrinology and Metabolism (JCEM). volum 84 (1).
  Vitenskapelig artikkel
• Aukrust, Pål; Müller, Fredrik; Lien, Egil; Nordøy, Ingvild; Liabakk, Nina-Beate; Kvale, Dag; Espevik, Terje; Frøland, Stig S.. (1999) Tumor necrosis factor (TNF) system levels in human immunodificiency virus-infected patients during highly active antiretroviral therapy: Perisistent TNF activation is associated with virologic and immunologic treatment failure. Journal of Infectious Diseases. volum 179.
  Vitenskapelig artikkel
• Børset, Magne; Hjort-Hansen, Henrik; Johnsen, Ann-Charlotte; Seidel, Carina; Waage, Anders; Espevik, Terje; Sundan, Anders. (1999) Apoptosis, proliferation and NF-k(kappa)B activation induced by agonistic Fas antibodies in the human myeloma cell line OH-2: amplification of Fas-mediated apoptosis by tumor necrosis factor. European Journal of Haematology. volum 63.
  Vitenskapelig artikkel
• Haux, Johan; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo; Sundan, Anders; Espevik, Terje. (1999) The role of IL-2 in regulating the sensitivity of NK cells for Fas-mediated apoptosis. Cancer Immunology and Immunotherapy. volum 48.
  Vitenskapelig artikkel
• Heine, Holger; Delude, Russell L.; Monks, Biran G.; Espevik, Terje; Golenbock, Douglas T.. (1999) Bacterial lipopolysaccharide induces expression of the stress response genes Hop and H411. Journal of Biological Chemistry. volum 274 (30).
  Vitenskapelig artikkel
• Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Sundan, Anders; Ashkenazi, Avi; Espevik, Terje. (1999) Regulation of Apo-2 Ligand/Trail expression in NK cells - Involvement in NK cell mediated cytotoxicity. Cytokine. volum 11 (9).
  Vitenskapelig artikkel
• Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Sundan, Anders; Ashkenazi, Avi; Espevik, Terje. (1999) Regulation of APO-2 ligand /Trail expression in NK cells - involvement in NK cell-mediated cytotoxicity. Cytokine. volum 11 (9).
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Espevik, Terje; Skjåk-Bræk, Gudmund. (1999) Behandling av diabetes mellitus med transplantasjon av immunbeskyttet øyvev fra pancreas. Tidsskrift for Den norske legeforening. volum 119 (28).
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild; Espevik, Terje. (1999) Transplantation of alginate microcapsules. Transplantation. volum 67 (7).
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Ryan, Liv; Andersson, Arne; King, Aileen; Faxvaag, Arild; Espevik, Terje. (1999) Transplantation of alginate microcapsules. Generation of antibodies against alginates and encapsulated porcine islet-like cell clusters. Transplantation. volum 67 (7).
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Vatten, Lars Johan; Espevik, Terje. (1999) Soluble tumor necrosis factor receptors in sera from patients with insulin-dependent diabetes mellitus: relations to duration and complications of disease. Acta Dermato-Venereologica. volum 36.
  Vitenskapelig artikkel
• Lien, Egil; Sellati, Timothy J.; Yoshimura, Atsutosi; Flo, Trude Helen; Rawadi, Georges; Finberg, Robert W.; Caroll, J.David; Espevik, Terje; Ingalls, Robin R; Radolf, Justin D.; Golenbock, Douglas T.. (1999) Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. Journal of Biological Chemistry. volum 274 (47).
  Vitenskapelig artikkel
• Aukrust, Pål; Muller, Fredrik; Lien, Egil; Nordøy, Ingvild; Liabakk, Nina-Beate; Kvale, Dag; Espevik, T; Frøland, Stig Sophus. (1999) Tumor necrosis factor (TNF) system in human immunodeficiency virus-infected patients during highly active antiretroviral therapy (HAART): Persistent TNF activation is associated with virologic and immunologic treatment failure. Journal of Infectious Diseases. volum 179 (1).
  Vitenskapelig artikkel
• Aukrust, Pål; Ueland, Thor; Lien, Egil; Bendtzen, Klaus; Muller, Fredrik; Andreassen, Arne K.; Nordøy, Ingvild; Aass, Halfdan; Espevik, T; Simonsen, Svein; Frøland, Stig Sophus; Gullestad, Lars. (1999) Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. American Journal of Cardiology. volum 83.
  Vitenskapelig artikkel
• Gullestad, Lars; Aukrust, Pål; Ueland, Thor; Espevik, T; Yee, G.; Vagelos, R.; Frøland, Stig Sophus; Fowler, M.B.. (1999) Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure. Journal of the American College of Cardiology. volum 34 (7).
  Vitenskapelig artikkel
• Johnsen, A-C; Steinkjer, B; Egeberg, Kathrine; Sundan, A; Espevik, Terje. (1999) The role of international-2 in regulation the sensitivity of natural killer celler for Fas-mediated apoptosis. European Journal of Haematology.
  Vitenskapelig artikkel
• Lien, E; Nonstad, Unni; Sundan, A; Espevik, Terje. (1999) Polymorphonuchlear of Fas and Fas-Ligand expression in NK cells by cytokines and the involved of Fas-Ligand in NK/LAK cell-mediated cytotoxicity. Cytokine.
  Vitenskapelig artikkel

1998

• Berntzen, G.; Flo, T; Medvedev, A; Kilaas, L; Skjåk-Bræk, Gudmund; Sundan, A; Espevik, Terje. (1998) The tumor necrosis factor-inducing potency of lipopolysaccharide and uronic acid polymers is increased when they are covalently linked to particles. Clinical and Vaccine Immunology.
  Vitenskapelig artikkel
• Halaas, Øyvind; Vik, R; Espevik, Terje. (1998) Induction of Fas ligand in murine bone marrow NK cells by bacterial polysaccharides. Immunology.
  Vitenskapelig artikkel
• Ingalls, RR; Monks, BG; Savedra R, [Mangler fornavn]; Christ, WJ; Delude, RL; Medvedev, AE; Espevik, Terje; Golenbock, DT. (1998) CD11/CD18 and CD14 share a common lipid A signaling pathway. Journal of Immunology.
  Vitenskapelig artikkel
• Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Nonstad, Unni; Egeberg, Kjartan Wøllo; Ashkenazi, Avi; Sundan, Anders; Espevik, Terje. (1998) Regulation of Apo-2 Ligand/TRAIL expression in NK cells - Involvement in NK cell mediated cytotoxicity. Journal of Interferon and Cytokine Research. volum 18 (5).
  Sammendrag/abstract
• Kulseng, Bård Eirik; Espevik, Terje; Sundan, A. (1998) Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus. Acta Dermato-Venereologica.
  Vitenskapelig artikkel
• Lien, E; Sundan, A; Aukrust, P; Frøland, S; Espevik, Terje. (1998) Elevated levels of serum-soluble CD14 in human immunodeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood.
  Vitenskapelig artikkel
• Lien, Egil; Aukrust, Pål; Sundan, Andreas; Muller, Fredrik; Frøland, Stig Sophus; Espevik, T. (1998) Elevated levels of serum-soluble CD14 in human immonudeficiency virus type 1 (HIV-1) infection: correlation to disease progression and clinical events. Blood. volum 92 (6).
  Vitenskapelig artikkel
• Medvedev, AE; Flo, T; Vogel, SN; Robin, R; Golenbock, DT; Teti, G; Espevik, Terje. (1998) Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-kappaB activation and TNF production induced by lipopolysaccharide and group B streptococcal cell walls. Journal of Immunology.
  Vitenskapelig artikkel
• Thommesen, Liv; Sjursen, Wenche; Gåsvik, Kathrine; Hanssen, Wenche; Brekke, Ole-Lars; Skattebøl, Lars; Holmeide, Anne Kristin; Espevik, Terje; Johansen, Berit; Lægreid, Astrid. (1998) Selective inhibitors of cytosolic or secretory phospholipase A2 block TNF-induced activation of transcription factor nuclear factor-kappa B and expression of ICAM-1. Journal of Immunology.
  Vitenskapelig artikkel

1997

• Aukrust, Pål; Hestad, Kjetil; Lien, Egil; Bjerkeli, Vigdis; Nordøy, Ingvild; Espevik, T; Muller, Fredrik; Frøland, Stig Sophus. (1997) Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-_a activity in human immunodeficiency virus type 1 infection. Journal of Infectious Diseases. volum 176 (4).
  Vitenskapelig artikkel
• Aukrust, Pål; Hestdal, Ketil; Lien, Egil; Bjerkeli, Vigdis; Nordøy, Ingvild; Espevik, Terje; Myller, Stig; Frøland, S.. (1997) Effects of intravenous immunoglobulin in vivo on abnormally increased tumor necrosis factor-alpha activity in human immunodeficiency virus type 1 infection. Journal of Infectious Diseases. volum 176.
  Vitenskapelig artikkel
• Hestad, Kjetil; Aukrust, Pål; Muller, Fredrik; Lien, Egil; Bjerkeli, Vigdis; Espevik, T; Frøland, Stig Sophus. (1997) Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1  infection: Low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load. Blood. volum 90 (7).
  Vitenskapelig artikkel
• Hestdal, Kjetil; Aukrust, Pål; Müller, Fredrik; Lien, Egil; Bjerkeli, Vigdis; Espevik, Terje; Frøland, Stig S.. (1997) Dysregulation of membrane-bound tumor necrosis factor-_a and tumor necrosis factor receptors on mononuclear cells in human immunodeficiency virus type 1 infection : low percentage of p75-tumor necrosis factor receptor positive cells in patients with advanced disease and high viral load. Blood. volum 90 (7).
  Vitenskapelig artikkel
• Jackson, A.M.; Lien, Egil; Alexandroff, A.B.; Espevik, Terje; James, K.; Selby, P.J.; Sundan, Anders. (1997) Soluble urinary CD14 after intravesical bacille Calmette-Guérin immunotherapy for carcinoma in situ. British Journal of Urology. volum 80.
  Vitenskapelig artikkel
• Jahr, Tove Gullstein; Ryan, Liv; Sundan, Anders; Lichenstein, Henri S.; Skjåk-Bræk, Gudmund; Espevik, Terje. (1997) Induction of tumor necrosis factor production from monocytes stimulated with mannuronic acid polymers and involvement of lipopolysaccharide-binding protein, CD14, and bactericidal/ permeability-increasing factor. Infection and Immunity. volum 65 (1).
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Thu, Beate; Espevik, Terje; Skjåk-Bræk, Gudmund. (1997) Alginate polylysine microcapsules as immune barrer : permeability of cytokines and immmunoglobulins over the capsule membrane. Cell Transplantation. volum 6 (4).
  Vitenskapelig artikkel
• Medvedev, Andrei E.; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Haux, Johan; Steinkjer, Bjørg; Egeberg, Kjartan Wøllo; Lynch, David H.; Sundan, Anders; Espevik, Terje. (1997) Regulation of Fas and Fas-Ligand expression in NK cells by cytokines and the involvement of Fas-Ligand in NK/LAK cell-mediated cytotoxicity. Cytokine. volum 9.
  Vitenskapelig artikkel
• Sandler, Stellan; Andersson, Arne; Eizirik, Décio L.; Hellerström, Claes; Espevik, Terje; Kulseng, Siri; Thu, Beate; Pipeleers, Daniel G.; Skjåk-Bræk, Gudmund. (1997) Assessment of insulin secretion in vitro from microencapsulated fetal procine islet-like cell clusters and rat, mouse, and human pancreatic islets. Transplantation. volum 63 (12).
  Vitenskapelig artikkel

1996

• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne K.; Müller, Fredrik; Haug, Charlotte J.; Espevik, Terje; Frøland, Stig S.. (1996) Persistent activation of the tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency : possible immunologic and clinical consequences. Blood. volum 87 (2).
  Vitenskapelig artikkel
• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne Karin; Muller, Fredrik; Haug, Charlotte J.; Espevik, T; Frøland, Stig Sophus. (1996) Persistant Activation of The Tumor Nevcrosis Factor System in a Subgroup of Patients With Common Varable Immunodeficincy - Possible Immunological and Clinical and Consequences. Blood. volum 87.
  Vitenskapelig artikkel
• Aukrust, Pål; Lien, Egil; Kristoffersen, Anne Karin; Muller, Fredrik; Haug, Charlotte J.; Espevik, T; Frøland, Stig Sophus. (1996) Persistent activation of tumor necrosis factor system in a subgroup of patients with common variable immunodeficiency - Possible immunologic and clinical concensus. Blood. volum 87 (2).
  Vitenskapelig artikkel
• Børset, Magne; Lien, Egil; Espevik, Terje; Helseth, Eirik; Waage, Anders; Sundan, Anders. (1996) Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines. Journal of Biological Chemistry. volum 271 (40).
  Vitenskapelig artikkel
• Børset, Magne; Medvedev, Andrei E.; Sundan, Anders; Espevik, Terje. (1996) The role of the two TNF receptors in proliferation, NF-_KB activation and discrimination between TNF and LT_a signalling in the human myeloma cell line OH-2. Cytokine. volum 8 (6).
  Vitenskapelig artikkel
• Haug, Charlotte J.; Aukrust, Pål; Lien, Egil; Muller, Fredrik; Espevik, T; Frøland, Stig Sophus. (1996) Disseminated Mycobacterium avium complex (MAC) infection in AIDS: Immunopathogenic significance of an activated tumor necrosis factor (TNF) system and depressed serum levels of 1,25-dihydroxyvitamin D. Journal of Infectious Diseases. volum 173.
  Vitenskapelig artikkel
• Haug, Charlotte J.; Aukrust, Pål; Lien, Egil; Müller, Fredrik; Espevik, Terje; Frøland, Stig S.. (1996) Disseminated Mycobacterium avium complex infection in AIDS : immunopathogenic significance of an activated tumor necrosis factor system and depressed serum levels of 1,25 dihydroxyvitamin D. Journal of Infectious Diseases. volum 173.
  Vitenskapelig artikkel
• Kulseng, Bård Eirik; Skjåk-Bræk, Gudmund; Følling, Ivar; Espevik, Terje. (1996) TNF production from peripheral blood mononuclear cells in diabetic patients after stimulation with alginate and lipopolysaccharide. Scandinavian Journal of Immunology. volum 43.
  Vitenskapelig artikkel
• Medvedev, Andrei E.; Espevik, Terje; Ranges, Gerald; Sundan, Anders. (1996) Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin _a effects. Journal of Biological Chemistry. volum 271 (16).
  Vitenskapelig artikkel
• Medvedev, Andrei E.; Lægreid, Astrid; Sundan, Anders; Espevik, Terje. (1996) A non-competitive P55 TNF receptor antibody enhances the specific activity of Lymphotoxin-_a. Scandinavian Journal of Immunology. volum 43 (4).
  Vitenskapelig artikkel
• Skjåk-Bræk, Gudmund; Espevik, Terje. (1996) Application of alginate gels in biotechnology and biomedicine. Carbohydrates in Europe. volum 14.
  Vitenskapelig artikkel
• Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, P.; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. I, Interaction between alginate and polycation. Biomaterials. volum 17.
  Vitenskapelig artikkel
• Thu, Beate; Bruheim, Per; Espevik, Terje; Smidsrød, Olav; Soon-Shiong, Patrick; Skjåk-Bræk, Gudmund. (1996) Alginate polycation microcapsules. II, Some functional properties. Biomaterials. volum 17.
  Vitenskapelig artikkel

1995

• Arntzen, KJ; Liabakk, N-B; Jacobsen, G.; Espevik, Terje; Austgulen, Rigmor. (1995) Soluble tumor necrosis factor receptor in serum and urine througout normal pregnancy and delivery. American Journal of Reproductive Immunology. volum 34.
  Vitenskapelig artikkel
• Lien, Egil; Liabakk, Nina-Beate; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Nonstad, Unni; Sundan, Anders; Espevik, Terje. (1995) Polymorphonuclear granulocytes enhance lipopolysaccharide-induced p75 tumor necrosis factor receptor release from mononuclear cells. European Journal of Immunology. volum 25.
  Vitenskapelig artikkel
• Skjermo, Jorunn; Defoort, Thomas; Dehasque, Marleen; Espevik, Terje; Olsen, Yngvar; Skjåk-Bræk, Gudmund; Sorgeloost, Patrick; Vadstein, Olav. (1995) Immunostimulation of juvenile turbot (Scophthalmus maximus L.) using an alginate with high mannuronic acid content administered via the live food organism Artemia. Fish and Shellfish Immunology. volum 5.
  Vitenskapelig artikkel
• Skjåk-Bræk, Gudmund; Espevik, Terje; Otterlei, Marit; Smidsrød, Olav; Soon-Shiong, P.. (1995) Homologous guluronic acid alginate coating composition for in vivo application and implantation and method using the same. 1995. US-Patent 5459 054, Oct. 1995.
  Rapport
• Samuelsen, Anne Berit; Paulsen, Berit Smestad; Wold, Jens Krisitian; Otsuka, Hanako; Yamada, Haruki; Espevik, T. (1995) Isolation and partial characterization of biologically active polysaccharides from Plantago major L. Phytotherapy Research. volum 9.
  Vitenskapelig artikkel

1994

• Halgunset, J; Johnsen, H; Kjøllesdal, AM; Qvigstad, E; Espevik, Terje; Austgulen, Rigmor. (1994) Normal parturition at term is associated with subtle inflammatory reactions in-utero. European Journal of Obstetrics, Gynecology, and Reproductive Biology. volum 56.
  Vitenskapelig artikkel
• Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1994) Cytokines in meningococcal disease. Baillière's Clinical Infectious Diseases. volum 1.
  Vitenskapelig artikkel
• Brekke, OL; Espevik, Terje; Bjerve, Kristian S. (1994) Butylated Hydroxyanisole Inhibits Tumor Necrosis Factor induced Cytotoxicity and Arachidonic Acid Release. Lipids. volum 29.
  Vitenskapelig artikkel

1993

• Austgulen, Rigmor; Kjøllesdal, AM; Johnsen, H; Liabakk, N-B; Espevik, Terje. (1993) Soluble receptors for tumor necrosis factor: occurence in association with normal delivery at term. Obstetrics and Gynecology. volum 82.
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, N-B; Lien, E; Espevik, Terje. (1993) Increased levels of soluble TNF-alpha receptors in serum from pregnant women, and in serum and urine samples from newborns. Pediatric Research. volum 33.
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, N-B; Richardsen, W; Rahimipoor, S; Vatn, I; Espevik, Terje. (1993) Serum levels of soluble TNF receptors are influenced by gestational age and delivery in normal pregnancy. Placenta. volum 14.
  Sammendrag/abstract
• Liabakk, N-B; Lien, E; Sundan, A; Sunde, A; Austgulen, Rigmor; Espevik, Terje. (1993) High concentrations of the soluble p55 tumor necrosis factor receptor in human seminal plasma. Human Reproduction. volum 8.
  Vitenskapelig artikkel
• Naume, Bjørn; Iversen, Ann-Charlotte; Johnsen, Ann-Charlotte; Espevik, Terje; Sundan, Anders. (1993) Gene expression and secretion of cytokines and cytokine receptors from hihgly purified CD56+ natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology. volum 23.
  Vitenskapelig artikkel
• Waage, A.; Halstensen, Alfred; Espevik, T.; Brandtzæg, P.. (1993) Compartmentalization of the TNF and IL-6 in meningitis and septic shock. Mediators of Inflammation. volum 2.
  Vitenskapelig artikkel
• Austgulen, Rigmor; Naume, B; Johnson, A-C; Espevik, Terje; Sundan, A. (1993) Gene expression and secretion of cytokines and cytokines from highly purified CD56* natural killer cells stimulated with interleukin-2, interleukin-7 and interleukin-12. European Journal of Immunology. volum 23.
  Vitenskapelig artikkel

1992

• Austgulen, Rigmor; Espevik, Terje; Mecsei, R; Scott, H. (1992) Expression of receptors for tumor necrosis factor in human placenta at term. Acta Obstetricia et Gynecologica Scandinavica. volum 71.
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, N-B; Espevik, Terje. (1992) Sekresjon av løselige reseptorer for tumor nekrose faktor - en immunologisk buffermekanisme under svangerskap?. Tidsskrift for Den norske legeforening. volum 112.
  Vitenskapelig artikkel
• Austgulen, Rigmor; Liabakk, NB; Brockhaus, M; Espevik, Terje. (1992) Soluble TNF receptors in amniotic fluid and in urine from pregnant women. Journal of Reproductive Immunology. volum 22.
  Vitenskapelig artikkel
• Brandtzæg, P.; Halstensen, Alfred; Kierulf, P.; Espevik, T.; Waage, A.. (1992) Molecular mechanisms in the compartmentalized inflammatory response presenting as meningococcal meningitis or septic shock. Microbial Pathogenesis. volum 13.
  Vitenskapelig artikkel
• Soon-Shong, P.; Feldman, E.; Nelson, R.; Komtebedde, J.; Smidsrød, Olav; Skjåk-Bræk, Gudmund; Espevik, Terje; Heintz, R.; Lee, M.. (1992) Successful reversal of spontaneous diabetes in dogs by intraperitonal microencapsulated islets. Transplantation. volum 54 (5).
  Vitenskapelig artikkel
• Waage, A.; Halstensen, Alfred; Brandtzæg, P.; Espevik, T.. (1992) TNF in serum in patients with bacterial infections. Recent Advances in Chemotherapy (Red: Adam, D., Lode, H., Rubinstein, E.).
  Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
• Brekke, OL; Espevik, Terje; Bardal, Tora; Bjerve, Kristian S. (1992) Effects of n-3 and n-6 fatty acids on Tumor Necrosis Factor cytotoxicity in WEHI fibrosarcoma cells. Lipids. volum 27.
  Vitenskapelig artikkel
• Brekke, OL; Shalaby, MR; Sundan, Anders; Espevik, Terje; Bjerve, Kristian S. (1992) Butylated hydroxyanisol specifically inhibits Tumor Necrosis Factor induced cytotoxicity and growth enhancement. Cytokine. volum 4.
  Vitenskapelig artikkel

1991

• Austgulen, Rigmor; Liabakk, N-B; Scott, H; Brockhaus, M; Espevik, Terje. (1991) Soluble TNF receptors in urine and in amniotic fluid from pregnant women. Placenta. volum 12.
  Sammendrag/abstract
• Waage, A.; Brandtzæg, P.; Espevik, T.; Halstensen, Alfred. (1991) Current understanding of the pathogenesis of gram negative shock. Infectious Disease Clinics of North America. volum 5.
  Vitenskapelig artikkel

1988

• Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1988) Synergistic growth inhibitory activity of tumor necrosis factor and interferon-alpha: contribution to the monocyte-derived cytostatic activity towards human leukemia K562 cells. Scandinavian Journal of Immunology. volum 28.
  Vitenskapelig artikkel
• Nissen-Meyer, J; Hofsli, E; Espevik, Terje; Austgulen, Rigmor. (1988) Involvement of tumor necrosis factor in cytotoxicity mediated by human monocytes. Natural immunity and cell growth regulation. volum 7.
  Vitenskapelig artikkel

1987

• Austgulen, Rigmor; Espevik, Terje; Degree, M. (1987) Monocyte-derived influence on growth of normal human fibroblasts: The contribution of tumor necrosis factor to growth inhibition. Scandinavian Journal of Immunology. volum 26.
  Vitenskapelig artikkel
• Austgulen, Rigmor; Espevik, Terje; Nissen-Meyer, J. (1987) Fibroblast growth stimulatory activity from human monocytes: The contribution of tumor necrosis factor. Scandinavian Journal of Immunology. volum 26.
  Vitenskapelig artikkel
• Nissen-Meyer, J; Austgulen, Rigmor; Espevik, Terje. (1987) Comparison of recombinant tumor necrosis factor and the monocyte-derived cytotoxic factor (CF) which is involved in the monocyte-mediated cytotoxicity. Cancer Research. volum 47.
  Vitenskapelig artikkel
• Bjerve, Kristian S; Espevik, Terje; Kildahl-Andersen, O; Nissen-Meyer, J. (1987) Effect of free fatty acids on the cytolytic activity of tumor necrosis factor/¬monocyte-derived cytotoxic factor. APMIS - Journal of Pathologiy, Microbiology and Immunology. volum 95.
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1986

• Austgulen, Rigmor; Espevik, Terje; Hammerstrøm, J; Nissen-Meyer, J. (1986) Role of monocyte cytotoxic factor in cytolysis of actinomycin D treated WEHI 164 cells mediated by freshly isolated human adherent mononuclear blood cells. Cancer Research. volum 46.
  Vitenskapelig artikkel
• Austgulen, Rigmor; Hammerstrøm, J; Espevik, Terje; Nissen-Meyer, J. (1986) Human monocyte cytotoxic factor mediates cytolysis of WEHI 164 cells. Cellular Immunology. volum 98.
  Vitenskapelig artikkel
• Austgulen, Rigmor; Kildahl-Andersen, O; Espevik, Terje. (1986) Monocyte-mediated drug-dependent cellular cytotoxicity: Effects of different WEHI 164 target cell lines. Cancer Immunology and Immunotherapy. volum 22.
  Vitenskapelig artikkel