2025

• Holthe, Erlend; Strand, Linn B; Dalen, Håvard; Klepstad, Pål; Mo, Rune; Angelsen, Aslaug Linnea. (2025) Pain and Chronic Musculoskeletal Pain in Individuals With Heart Failure Compared With the General Population: The HUNT Study. Journal of Cardiovascular Nursing
  Vitenskapelig artikkel
• Vagnildhaug, Ola Magne; Habberstad, Ragnhild Hansdatter; Salvesen, Øyvind Olav; Balstad, Trude Rakel; Bye, Asta; Dajani, Olav. (2025) A comparison of inflammatory markers’ potential to predict weight loss in advanced cancer: a prospective observational study. Journal of Circulating Biomarkers (JCB)
  Vitenskapelig artikkel
• Hofstad, Janne Kristin; Wik, Tina Strømdal; Klepstad, Pål; Gjeilo, Kari Hanne; Winther, Siri Bjørgen; Foss, Olav A.. (2025) In-Hospital Pain and Opioid Consumption After Primary Total Knee Arthroplasty Compared to Primary Total Hip Arthroplasty: Results from 7330 Patients Treated in a Fast-Track Setting. Pain and Therapy
  Vitenskapelig artikkel

2024

• Minnai, Francesca; Shkodra, Morena; Noci, Sara; Brunelli, Cinzia; Pigni, Alessandra; Zecca, Ernesto. (2024) Genomic Study in Opioid-Treated Cancer Patients Identifies Variants Associated With Nausea-Vomiting. Journal of Pain and Symptom Management
  Vitenskapelig artikkel
• Wong, Aaron K.; Vogrin, Sara; Klepstad, Pål; Rubio, Justin; Le, Brian; Philip, Jennifer. (2024) Do CYP2D6 genotypes affect oxycodone dose, pharmacokinetics, pain, and adverse effects in cancer?. Pharmacogenomics (London)
  Vitenskapelig artikkel
• Cilla, Savino; Rossi, Romina; Habberstad, Ragnhild Hansdatter; Klepstad, Pål; Dall'Agata, Monia; Kaasa, Stein. (2024) Explainable Machine Learning Model to Predict Overall Survival in Patients Treated With Palliative Radiotherapy for Bone Metastases. JCO Clinical Cancer Informatics
  Vitenskapelig artikkel
• Anthon, Carl Thomas; Pène, Frédéric; Perner, Anders; Azoulay, Elie; Puxty, Kathryn; Louw, Andry Van De. (2024) Platelet transfusions in adult ICU patients with thrombocytopenia: A sub-study of the PLOT-ICU inception cohort study. Acta Anaesthesiologica Scandinavica
  Vitenskapelig artikkel
• Barratt, Daniel T.; Klepstad, Pål; Dale, Ola; Kaasa, Stein; Somogyi, Andrew A.. (2024) Pharmacokinetic and neuroimmune pharmacogenetic impacts on slow-release morphine cancer pain control and adverse effects. The Pharmacogenomics Journal
  Vitenskapelig artikkel

2023

• Aslam, Tayyba Naz; Klitgaard, Thomas L.; Ahlstedt, Christian A. O.; Andersen, Finn Husøy; Chew, Michelle S.; Collet, Marie O.. (2023) A survey of preferences for respiratory support in the intensive care unit for patients with acute hypoxaemic respiratory failure. Acta Anaesthesiologica Scandinavica
  Vitenskapelig artikkel
• Maltoni, Marco; Caraceni, Augusto Tomasso Giovanni; Klepstad, Pål; Rossi, Romina. (2023) Editorial: Early palliative care for cancer patients. Frontiers in Oncology
  Leder
• Løhre, Erik Torbjørn; Svedahl, Augstein; Jakobsen, Gunnhild; Solheim, Tora S; Klepstad, Pål; Thronæs, Morten. (2023) Emergency Palliative Cancer Care: Dexmedetomidine Treatment Experiences—A Retrospective Brief Report on Nine Consecutive Cases. Pain and Therapy
  Vitenskapelig artikkel

2022

• Habberstad, Ragnhild H; Aass, Nina Kathrine; Mollnes, Tom Eirik; Damås, Jan Kristian; Brunelli, Cinzia; Rossi, Romina. (2022) Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases. Journal of Pain and Symptom Management
  Vitenskapelig artikkel
• Waagsbø, Bjørn; Stuve, Nora; Afset, Jan Egil; Klepstad, Pål; Mo, Skule; Heggelund, Lars. (2022) High levels of discordant antimicrobial therapy in hospital-acquired bloodstream infections is associated with increased mortality in an intensive care, low antimicrobial resistance setting. Infectious Diseases
  Vitenskapelig artikkel
• Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Skaug, Thomas Renhult; Nordseth, Trond. (2022) Characteristics of circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study. Open heart
  Vitenskapelig artikkel
• Rian, Torbjørn; Sand, Kari; Skogvoll, Eirik; Klepstad, Pål; Wik, Tina Strømdal. (2022) A Web-Based Communication Tool for Postoperative Follow-up and Pain Assessment at Home After Primary Knee Arthroplasty: Feasibility and Usability Study. JMIR Formative Research
  Vitenskapelig artikkel

2021

• Langeland, Halvor; Bergum, Daniel; Nordseth, Trond; Løberg, Magnus; Skaug, Thomas Renhult; Bjørnstad, Knut. (2021) Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study. BMC Anesthesiology
  Vitenskapelig artikkel

2020

• Rian, Torbjørn; Skogvoll, Eirik; Hofstad, Janne Kristin; Høvik, Lise Husby; Winther, Siri Bjørgen; Husby, Vigdis Schnell. (2020) Tapentadol versus oxycodone for postoperative pain treatment the first 7 days after total knee arthroplasty: a randomized clinical trial. Pain
  Vitenskapelig artikkel
• Andersen, Siri Kojen; Hustveit, Ragnhild; Frøland, Erlend; Uleberg, Oddvar; Kruger, Andreas; Klepstad, Pål. (2020) Improper monitoring and deviations from physiologic treatment goals in patients with brain injury in the early phases of emergency care. Journal of clinical monitoring and computing
  Vitenskapelig artikkel

2019

• Jakobsen, Gunnhild; Engstrøm, Morten; Thronæs, Morten; Løhre, Erik Torbjørn; Kaasa, Stein; Fayers, Peter. (2019) Sleep quality in hospitalized patients with advanced cancer: an observational study using self-reports of sleep and actigraphy. Supportive Care in Cancer
  Vitenskapelig artikkel
• Kurita, Geana Paula; Sjøgren, Per Johan E; Klepstad, Pål; Mercadante, Sebastiano. (2019) Interventional techniques to management of cancer-related pain: Clinical and critical aspects. Cancers
  Vitenskapelig artikkel
• Brede, Jostein Rødseth; Lafrenz, Thomas; Klepstad, Pål; Skjærseth, Eivinn Årdal; Nordseth, Trond; Søvik, Edmund. (2019) Feasibility of Pre-Hospital Resuscitative Endovascular Balloon Occlusion of the Aorta in Non-Traumatic Out-of-Hospital Cardiac Arrest. Journal of the American Heart Association (JAHA)
  Vitenskapelig artikkel
• Klepstad, Pia Katrin; Nordseth, Trond; Sikora, Normunds; Klepstad, Pål. (2019) Use of national early warning score for observation for increased risk for clinical deterioration during post-ICU care at a surgical ward. Therapeutics and Clinical Risk Management
  Vitenskapelig artikkel
• Frøland, Erlend; Nordseth, Trond; Krüger, Andreas; Klepstad, Pål; Uleberg, Oddvar. (2019) Physiological stability in patients with acute ischemic cerebral insult during the prehospital treatment phase. NTNU NTNU
  Mastergradsoppgave

2018

• Uleberg, Oddvar; Pape, Kristine; Kristiansen, Thomas; Romundstad, Pål Richard; Klepstad, Pål. (2018) Population-based analysis of the impact of trauma on longer-term functional outcomes. British Journal of Surgery
  Vitenskapelig artikkel
• Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo; Mørkeset, Siri Tessem. (2018) The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain. BMC Palliative Care
  Vitenskapelig artikkel
• Furst, Per; Lundström, Staffan; Klepstad, Pål; Runesdottir, S; Strang, P. (2018) Improved pain control in terminally ill cancer patients by introducing low-dose oral methadone in addition to on-going opioid treatment. Journal of Palliative Medicine
  Vitenskapelig artikkel

2017

• Andersen, Finn Husøy; Kvåle, Reidar; Flaatten, Hans; Klepstad, Pål. (2017) Intensive care for the very old : ICU admission triage and outcomes. Norwegian University of Science and Technology, Faculty of Medicine Norwegian University of Science and Technology, Faculty of Medicine
  Doktorgradsavhandling
• Gjeilo, Kari Hanne; Wahba, Alexander; Klepstad, Pål; Lydersen, Stian; Stenseth, Roar. (2017) Long-term health-related quality of life and survival in patients after cardiac surgery - a prospective cohort study. European Journal of Cardiovascular Nursing
  Sammendrag/Abstract
• Haugdahl, Hege Selnes; Dahlberg, Helena; Klepstad, Pål; Storli, Sissel Lisa. (2017) The breath of life. Patients? experiences of breathing during and after mechanical ventilation. Intensive and Critical Care Nursing
  Vitenskapelig artikkel
• Raj, Sunil Xavier; Brunelli, Cinzia; Klepstad, Pål; Kaasa, Stein. (2017) COMBAT study - Computer based assessment and treatment - A clinical trial evaluating impact of a computerized clinical decision support tool on pain in cancer patients. Scandinavian Journal of Pain
  Vitenskapelig artikkel
• Paulsen, Ørnulf; Laird, Barry J; Aass, Nina Kathrine; Lea, Tor Erling; Fayers, Peter; Kaasa, Stein. (2017) The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer. PLOS ONE
  Vitenskapelig artikkel

2016

• Seternes, Arne; Fasting, Sigurd; Klepstad, Pål; Mo, Skule; Dahl, Torbjørn; Bjørck, Martin. (2016) Bedside dressing changes for open abdomen in the intensive care unit is safe and time and staff efficient. Critical Care
  Vitenskapelig artikkel
• Rosland, Jan Henrik; Borchgrevink, Petter Chr.; Klepstad, Pål; Kongsgaard, Ulf. (2016) Smertebehandling hos pasienter som har kreft. Universitetet I Oslo, Det medisinske fakultet, Institutt for klinisk medisin, Avdeling for farmakologi Universitetet I Oslo, Det medisinske fakultet, Institutt for klinisk medisin, Avdeling for farmakologi
  Lærebok

2015

• Paulsen, Ørnulf; Aass, Nina Kathrine; Klepstad, Pål; Kaasa, Stein. (2015) Reply to A. Molfino et al. Journal of Clinical Oncology
  Leserinnlegg
• Klepstad, Pål; Skorpen, Frank. (2015) Genetic variability of pain - a patient focused endpoint. Scandinavian Journal of Pain
  Leder
• Lee, Yong Joo; Suh, Sang-Yeon; Song, Junghan; Lee, Sanghee Shiny; Seo, Ah-Ram; Ahn, Hong-Yup. (2015) Serum and urine concentrations of morphine and morphine metabolites in patients with advanced cancer receiving continuous intravenous morphine: An observational study Cancer palliative care. BMC Palliative Care
  Vitenskapelig artikkel
• Stuedahl, Marit; Vold, Sissel; Stafseth, Siv Anna Ulla-Britt Karlsson; Klepstad, Pål. (2015) Interrater reliability of Nursing Activities Score among Intensive Care Unit health professionals. Revista da Escola de Enfermagem da USP
  Vitenskapelig artikkel
• MacLeod, Nicholas; Klepstad, Pål; Fallon, Marie; Laird, Barry J.. (2015) Pain mangement in mesothelioma. Journal of Palliative Care & Medicine
  Vitenskapelig oversiktsartikkel/review

2014

• Paulsen, Ørnulf; Klepstad, Pål; Rosland, Jan Henrik; Aass, Nina Kathrine; Albert, Eva; Fayers, Peter. (2014) Efficacy of methylprednisolone on pain, fatigue, and appetite loss in patients with advanced cancer using opioids: A randomized, placebo-controlled, double-blind trial. Journal of Clinical Oncology
  Vitenskapelig artikkel
• Raj, Sunil; Thronæs, Morten; Brunelli, Cinzia; Hjermstad, Marianne Jensen; Klepstad, Pål; Kaasa, Stein. (2014) A cross-sectional study on prevalence of pain and breakthrough pain among an unselected group of outpatients in a tertiary cancer clinic. Supportive Care in Cancer
  Vitenskapelig artikkel
• Klepstad, Pål. (2014) Polymorphism in the mu-opioid receptor gene OPRM1 A118G. an example of the enigma og genetic variability behind chronic pain. Scandinavian Journal of Pain
  Leder
• Jakobsen, Gunnhild; Knudsen, Anne Kari; Klepstad, Pål. (2014) Wake up, sleep is important! Managing sleep disturbance in patients with advanced cancer. European Journal of Palliative Care
  Vitenskapelig artikkel
• Sandrød, Oddrun; Klepstad, Pål; Stenseth, Roar; Gjeilo, Kari Hanne. (2014) Survival and health-related quality of life in cardiac surgery patients with ICU length of stay more than one day. A 5-year follow-up study. European Journal of Cardiovascular Nursing
  Sammendrag/Abstract
• Sprangers, Mirjam A. G.; Thong, Melissa S. Y.; Bartels, Meike; Barsevick, Andrea; Ordonana, Juan; Shi, Quiling. (2014) Biological pathways, candidate genes, and molecular markers associated with quality-of-life domains: an update. Quality of Life Research
  Vitenskapelig artikkel

2013

• Fladvad, Torill; Klepstad, Pål; Langaas, Mette; Dale, Ola; Kaasa, Stein; Caraceni, Augusto. (2013) Variability in UDP-glucuronosyltransferase genes and morphine metabolism. Observations from a cross-sectional multicenter study in advanced cancer patients with pain. Pharmacogenetics & Genomics
  Vitenskapelig artikkel
• Klepstad, Pål. (2013) Pharmacokinetics of opioids. Influenced by genetic variability. Minerva Anestesiologica
  Vitenskapelig oversiktsartikkel/review
• Bjelland, Thor Wilhelm; Hjertner, Øyvind; Klepstad, Pål; Kaisen, Kjell; Dale, Ola; Haugen, Bjørn Olav. (2013) Clopidogrel does not work following cardiopulmonary resuscitation. European Journal of Clinical Pharmacology
  Leserinnlegg
• Nekolaichuk, Cheryl; Fainsinger, Robin; Aass, Nina Kathrine; Hjermstad, Marianne Jensen; Knudsen, Anne Kari; Klepstad, Pål. (2013) The Edmonton Classification System for Cancer Pain: Comparison of Pain Classification Features and Pain Intensity Across Diverse Palliative Care Settings in Eight Countries. Journal of Palliative Medicine
  Vitenskapelig artikkel

2012

• Klepstad, Pål. (2012) Start av opioider til kreftpasienter. Best Practice Onkologi/Hematologi
  Fagartikkel
• Knudsen, Anne Kari; Klepstad, Pål; Caraceni, Augusto; Kaasa, Stein; Brunelli, C; Aass, Nina Kathrine. (2012) Cancer pain undertreatment and prognostic factors Response. Pain
  Leserinnlegg

2011

• Laugsand, Eivor Alette; Jakobsen, Gunnhild; Kaasa, Stein; Klepstad, Pål. (2011) Inadequate symptom control in advanced cancer patients across Europe. Supportive Care in Cancer
  Vitenskapelig artikkel
• Kurita, Geana; Sjøgren, Per; Ekholm, Ola; Kaasa, Stein; Loge, Jon Håvard; Poviloniene, Irena. (2011) Prevalence and Predictors of Cognitive Dysfunction in Opioid-Treated Patients With Cancer: A Multinational Study. Journal of Clinical Oncology
  Vitenskapelig artikkel
• Klepstad, Pål; Kaasa, Stein; Borchgrevink, Petter Chr.. (2011) Starting Step III opioids for moderate to severe pain in cancer patients: Dose titration: A systematic review. Palliative Medicine
  Vitenskapelig oversiktsartikkel/review

2010

• Bjelland, Thor Wilhelm; Dale, Ola; Kaisen, K; Haugen, Bjørn Olav; Lydersen, Stian; Strand, K. (2010) REMIFENTANIL plus PROPOFOL VS. FENTANYL plus MIDAZOLAM FOR SEDATION DURING THERAPEUTIC HYPOTHERMIA: A RANDOMISED CONTROLLED TRIAL. Intensive Care Medicine
  Sammendrag/Abstract
• Fayers, Peter; Klepstad, Pål; Kaasa, Stein. (2010) Are Studies in Palliative Care Biased? Characteristics of Patients Recruited to the EPOS Study. Palliative Medicine
  Sammendrag/Abstract
• Torgersen, Johan; Strand, Kristian; Bjelland, Thor W.; Klepstad, Pål; Kvåle, Reidar; Søreide, Eldar. (2010) Cognitive dysfunction and health-related quality of life after a cardiac arrest and therapeutic hypothermia. Acta Anaesthesiologica Scandinavica
  Vitenskapelig artikkel
• Klepstad, Pål; Fladvad, Torill; Skorpen, Frank; Bjordal, Kristin; Caraceni, Augusto; Dale, Ola. (2010) The European Pharmacogenetic Opioid Study (EPOS): Influence from Genetic Variability on Opioid Use un 2209 Cancer Pain Patients. Palliative Medicine
  Sammendrag/Abstract
• Klepstad, Pål. (2010) Intensivmedisinen og dens utfordringer. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Leder

2009

• Laugsand, Eivor Alette; Kaasa, Stein; Conno, Franco De; Hanks, Geoffrey; Klepstad, Pål. (2009) Intensity and treatment of symptoms in 3030 palliative care patients: A cross-sectional survey of the EAPC Research Network. Journal of Opioid Management
  Vitenskapelig artikkel
• Lotsch, J; Klepstad, Pål; Doehring, A; Dale, Ola. (2009) A GTP cyclohydrolase 1 genetic variant delays cancer pain. Pain
  Vitenskapelig artikkel

2008

• Storm, Hanne; Skorpen, Frank; Klepstad, Pål; Støen, Randi; Ræder, Johan. (2008) Genetically variation influence the skin conductance response to nociceptive pain in anesthetized patients. NAForum
  Sammendrag/Abstract
• Moen, Kent Gøran; Klepstad, Pål; Skandsen, Toril; Fredriksli, Oddrun; Vik, Anne. (2008) Direct transport versus interhospital transfer of patients with severe head injury in Norway. European journal of emergency medicine
  Vitenskapelig artikkel
• Klepstad, Pål; Kaasa, Stein. (2008) Predication of cancer patients' survival by pain interference items is not the same as evidence that pain intensity is a survival predictor. Journal of Clinical Oncology
  Vitenskapelig artikkel
• Tveita, Torkjel; Thoner, Just; Klepstad, P; Dale, Ola; Jystad, A; jystad, a. (2008) A controlled comparison between single doses of intravenous and intramuscular morphine with respect to analgesic effects and patient safety. Acta Anaesthesiologica Scandinavica
  Vitenskapelig artikkel

2007

• Klepstad, Pål. (2007) Professional life in ICU Norwegian care. ICU management
  Vitenskapelig oversiktsartikkel/review
• Klepstad, Pål; Guttormsen, Anne Berit; Dale, O.. (2007) Common sense won: engagement from experts repealed Norwegian restrictions for ICU research. Intensive Care Medicine
  Vitenskapelig artikkel

2006

• Fredheim, Olav Magnus; Borchgrevink, Petter Chr.; Klepstad, Pål; Kaasa, Stein; Dale, Ola. (2006) Long term methadone for chronic pain: A pilot study of pharmacokinetic aspects. European Journal of Pain
  Vitenskapelig artikkel
• Dale, Ola; Nilsen, Turid; Loftsson, Thorstein; Tønnesen, Hanne Hjort; Tønnesen, Hanne Hjorth; Klepstad, Pål. (2006) Intranasal midazolam: a comparison of two delivery devices in human volunteers. Journal of Pharmacy and Pharmacology (JPP)
  Vitenskapelig artikkel

2005

• Eide, Trine Olberg; Romundstad, Pål Richard; Klepstad, Pål; Myhre, Hans Olav. (2005) Health related quality of life in long term-survivors following thoracoabdominal aortic aneurysm repair. Journal of Vascular Nursing
  Vitenskapelig artikkel
• Kaasa, Stein; Klepstad, Pål. (2005) Kreftpasienten skal ikke ha smerter. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Leder
• Dale, Ola; Klepstad, Pål. (2005) Biobankloven stanser forskning på kritisk syke pasienter. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Leserinnlegg
• Seland, Mette; Kaasa, Stein; Klepstad, Pål. (2005) Symptomregistrering hos kreftpasienter ved sykehusinnleggelse. Tidsskrift for Den norske legeforening (Tidsskriftet)
  Vitenskapelig artikkel

2004

• Klepstad, Pål; Hilton, Priscilla; Moen, Jorunn; Kaasa, Stein; Borchgrevink, Petter Chr.; Zahlsen, Kolbjørn. (2004) Day-to-day variations during clinicaøl drug monitoring of morphine, morphine-3-glucuronide and morphine-6-glucuronide serum concentrations in cancer patients. A prospective observational study. BMC Clinical Pharmacology
  Vitenskapelig artikkel

2003

• Klepstad, Pål; Gisvold, Sven Erik. (2003) End-of-life care in intensive care units. Save lives that can be saved, offer the dying a peaceful and dignified death. Acta Anaesthesiologica Scandinavica
  Vitenskapelig artikkel

2002

• Klepstad, Pål; Loge, Jon Håvard; Borchgrevink, P.; Mendoza, T.; Cleeland, C.S.; Kaasa, Stein. (2002) The Norwegian Brief Pain Inventory questionnaire: translation and validation in cancer pain patients. Journal of Pain and Symptom Management
  Vitenskapelig artikkel
• Klepstad, Pål; Loge, Jon Håvard; Borchgrevink, Petter Chr.; Kaasa, Stein. (2002) The Norwegian Brief Pain Inventory. Translation and validation in cancer patients. Journal of Pain and Symptom Management
  Vitenskapelig artikkel
• Kaasa, Stein; Klepstad, Pål. (2002) Palliativ medisin i intensivavdelingen.
  Kronikk

2000

• Klepstad, Pål; Borchgrevink, Petter Chr.; Kaasa, Stein. (2000) Effects on cancer patients health related quality of life from start of morphine. Journal of Pain and Symptom Management
  Vitenskapelig artikkel

1998

• Hole, Anton; Klepstad, Pål. (1998) Why monitor sedation in intensive care unit patients?.
  Vitenskapelig Kapittel/Artikkel/Konferanseartikkel