Nathan Robert Scrimgeour
Om
Nathan has a 50% position as an engineer at K. G. Jebsen – Center of Exercise in Medicine and a 50% position as project engineer for Dr. Morten Høydal, both within the Department of Circulation and Diagnostic Imaging at NTNU.
Nathan completed his PhD in 2012 in his hometown at the University of Adelaide, Australia. There he studied the biochemical and biophysical properties of store operated Ca2+ channels. In his time since at NTNU he has applied his skills as a patch clamp electrophysiologist to help to characterise the electrophysiological and Ca2+ handling properties of the heart in exercise and disease animal models.
In addition to patch clamp electrophysiology, Nathan also has technical expertise in cell culture, molecular biology and laboratory animal handling techniques.
Kompetanseord
Publikasjoner
2022
-
Aakerøy, Lars;
Cheng, Chew W.;
Sustova, Pavla;
Scrimgeour, Nathan Robert;
Wahl, Sissel Gyrid Freim;
Steinshamn, Sigurd Loe;
Bowen, T Scott;
Brønstad, Eivind.
(2022)
Identification of exercise-regulated genes in mice exposed to cigarette smoke.
Physiological Reports.
volum 10 (21).
Vitenskapelig artikkel
-
Huuha, Aleksi Matias;
Norevik, Cecilie Skarstad;
Moreira, Jose Bianco Nascimento;
Kobro-Flatmoen, Asgeir;
Scrimgeour, Nathan Robert;
Kivipelto, Miia;
Van Praag, Henriette;
Ziaei, Maryam;
Sando, Sigrid Botne;
Wisløff, Ulrik;
Tari, Atefe R.
(2022)
Can exercise training teach us how to treat Alzheimer's disease?.
Ageing Research Reviews.
volum 75.
Vitenskapelig oversiktsartikkel/review
2021
-
Marwarha, Gurdeep;
Røsand, Øystein;
Scrimgeour, Nathan Robert;
Slagsvold, Katrine Hordnes;
Høydal, Morten.
(2021)
miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner.
Biomedicines.
volum 10 (1).
Vitenskapelig artikkel
2020
-
Stølen, Tomas;
Høydal, Morten;
Ahmed, Muhammad Shakil;
Jørgensen, Kari;
Garten, Karin;
Hortigon-Vinagre, Maria;
Zamora, Victor;
Scrimgeour, Nathan Robert;
Berre, Anne Marie Ormbostad;
Nes, Bjarne;
Skogvoll, Eirik;
Johnsen, Anne Berit;
Moreira, Jose Bianco Nascimento;
McMullen, Julie R;
Attramadal, Håvard;
Smith, Godfrey L;
Ellingsen, Øyvind;
Wisløff, Ulrik.
(2020)
Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction.
Journal of Molecular and Cellular Cardiology.
volum 148.
Vitenskapelig artikkel
2019
-
Scrimgeour, Nathan Robert;
Wrobel, Aleksandra Zofia;
Pinho, Maria;
Høydal, Morten.
(2019)
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
American Journal of Physiology - Cell Physiology.
volum 318 (1).
Vitenskapelig artikkel
-
Tari, Atefe R;
Norevik, Cecilie Skarstad;
Scrimgeour, Nathan Robert;
Kobro-Flatmoen, Asgeir;
Storm-Mathisen, Jon;
Bergersen, Linda Hildegard;
Wrann, Christiane D.;
Selbæk, Geir;
Kivipelto, Miia;
Moreira, Jose Bianco Nascimento;
Wisløff, Ulrik.
(2019)
Are the Neuroprotective Effects of Exercise Training Systemically Mediated?.
Progress in cardiovascular diseases.
volum 62 (2).
Vitenskapelig oversiktsartikkel/review
2017
-
Pinho, Maria;
Scrimgeour, Nathan Robert;
Stølen, Tomas;
Garten, Karin;
Sharma, Animesh;
Fonseca, Davi de Miranda;
Smith, Godfrey L;
Høydal, Morten.
(2017)
Modeling of cardiac ischaemia and reperfusion injury: a human-based in vitro model using iPS-derived cardiomyocytes.
European Heart Journal.
volum 38 (1).
Sammendrag/abstract
-
Scrimgeour, Nathan Robert;
Pinho, Maria;
Wrobel, Aleksandra Zofia;
Høydal, Morten.
(2017)
MicroRNA-451a regulate expression and activity of matrix metalloproteinases 2 and 9 in human cardiomyocytes.
European Heart Journal.
volum 38 (1).
Sammendrag/abstract
Tidsskriftspublikasjoner
-
Aakerøy, Lars;
Cheng, Chew W.;
Sustova, Pavla;
Scrimgeour, Nathan Robert;
Wahl, Sissel Gyrid Freim;
Steinshamn, Sigurd Loe;
Bowen, T Scott;
Brønstad, Eivind.
(2022)
Identification of exercise-regulated genes in mice exposed to cigarette smoke.
Physiological Reports.
volum 10 (21).
Vitenskapelig artikkel
-
Huuha, Aleksi Matias;
Norevik, Cecilie Skarstad;
Moreira, Jose Bianco Nascimento;
Kobro-Flatmoen, Asgeir;
Scrimgeour, Nathan Robert;
Kivipelto, Miia;
Van Praag, Henriette;
Ziaei, Maryam;
Sando, Sigrid Botne;
Wisløff, Ulrik;
Tari, Atefe R.
(2022)
Can exercise training teach us how to treat Alzheimer's disease?.
Ageing Research Reviews.
volum 75.
Vitenskapelig oversiktsartikkel/review
-
Marwarha, Gurdeep;
Røsand, Øystein;
Scrimgeour, Nathan Robert;
Slagsvold, Katrine Hordnes;
Høydal, Morten.
(2021)
miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner.
Biomedicines.
volum 10 (1).
Vitenskapelig artikkel
-
Stølen, Tomas;
Høydal, Morten;
Ahmed, Muhammad Shakil;
Jørgensen, Kari;
Garten, Karin;
Hortigon-Vinagre, Maria;
Zamora, Victor;
Scrimgeour, Nathan Robert;
Berre, Anne Marie Ormbostad;
Nes, Bjarne;
Skogvoll, Eirik;
Johnsen, Anne Berit;
Moreira, Jose Bianco Nascimento;
McMullen, Julie R;
Attramadal, Håvard;
Smith, Godfrey L;
Ellingsen, Øyvind;
Wisløff, Ulrik.
(2020)
Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction.
Journal of Molecular and Cellular Cardiology.
volum 148.
Vitenskapelig artikkel
-
Scrimgeour, Nathan Robert;
Wrobel, Aleksandra Zofia;
Pinho, Maria;
Høydal, Morten.
(2019)
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
American Journal of Physiology - Cell Physiology.
volum 318 (1).
Vitenskapelig artikkel
-
Tari, Atefe R;
Norevik, Cecilie Skarstad;
Scrimgeour, Nathan Robert;
Kobro-Flatmoen, Asgeir;
Storm-Mathisen, Jon;
Bergersen, Linda Hildegard;
Wrann, Christiane D.;
Selbæk, Geir;
Kivipelto, Miia;
Moreira, Jose Bianco Nascimento;
Wisløff, Ulrik.
(2019)
Are the Neuroprotective Effects of Exercise Training Systemically Mediated?.
Progress in cardiovascular diseases.
volum 62 (2).
Vitenskapelig oversiktsartikkel/review
-
Pinho, Maria;
Scrimgeour, Nathan Robert;
Stølen, Tomas;
Garten, Karin;
Sharma, Animesh;
Fonseca, Davi de Miranda;
Smith, Godfrey L;
Høydal, Morten.
(2017)
Modeling of cardiac ischaemia and reperfusion injury: a human-based in vitro model using iPS-derived cardiomyocytes.
European Heart Journal.
volum 38 (1).
Sammendrag/abstract
-
Scrimgeour, Nathan Robert;
Pinho, Maria;
Wrobel, Aleksandra Zofia;
Høydal, Morten.
(2017)
MicroRNA-451a regulate expression and activity of matrix metalloproteinases 2 and 9 in human cardiomyocytes.
European Heart Journal.
volum 38 (1).
Sammendrag/abstract
Formidling
2017
-
PosterLjones, Kristine; Ness, Henning Ofstad; Scrimgeour, Nathan Robert; Høydal, Morten. (2017) An acute bout of exhaustive endurance exercise induces upregulation of transcripts encoding calcium handling proteins in the right ventricle. 15th Annual CHFR Symposium on Heart Failure ; 2017-09-20 - 2017-09-22.