Nathan Robert Scrimgeour

Om

Nathan has a 50% position as an engineer at K. G. Jebsen – Center of Exercise in Medicine and a 50% position as project engineer for Dr. Morten Høydal, both within the Department of Circulation and Diagnostic Imaging at NTNU.

Nathan completed his PhD in 2012 in his hometown at the University of Adelaide, Australia. There he studied the biochemical and biophysical properties of store operated Ca2+ channels. In his time since at NTNU he has applied his skills as a patch clamp electrophysiologist to help to characterise the electrophysiological and Ca2+ handling properties of the heart in exercise and disease animal models.

In addition to patch clamp electrophysiology, Nathan also has technical expertise in cell culture, molecular biology and laboratory animal handling techniques.

Publikasjoner

2022

Aakerøy, Lars; Cheng, Chew W.; Sustova, Pavla; Scrimgeour, Nathan Robert; Wahl, Sissel Gyrid Freim; Steinshamn, Sigurd Loe; Bowen, T Scott; Brønstad, Eivind. (2022) Identification of exercise-regulated genes in mice exposed to cigarette smoke. Physiological Reports. volum 10 (21).
Vitenskapelig artikkel
Huuha, Aleksi Matias; Norevik, Cecilie Skarstad; Moreira, Jose Bianco Nascimento; Kobro-Flatmoen, Asgeir; Scrimgeour, Nathan Robert; Kivipelto, Miia; Van Praag, Henriette; Ziaei, Maryam; Sando, Sigrid Botne; Wisløff, Ulrik; Tari, Atefe R. (2022) Can exercise training teach us how to treat Alzheimer's disease?. Ageing Research Reviews. volum 75.
Vitenskapelig oversiktsartikkel/review

2021

Marwarha, Gurdeep; Røsand, Øystein; Scrimgeour, Nathan Robert; Slagsvold, Katrine Hordnes; Høydal, Morten. (2021) miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner. Biomedicines. volum 10 (1).
Vitenskapelig artikkel

2020

Stølen, Tomas; Høydal, Morten; Ahmed, Muhammad Shakil; Jørgensen, Kari; Garten, Karin; Hortigon-Vinagre, Maria; Zamora, Victor; Scrimgeour, Nathan Robert; Berre, Anne Marie Ormbostad; Nes, Bjarne; Skogvoll, Eirik; Johnsen, Anne Berit; Moreira, Jose Bianco Nascimento; McMullen, Julie R; Attramadal, Håvard; Smith, Godfrey L; Ellingsen, Øyvind; Wisløff, Ulrik. (2020) Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction. Journal of Molecular and Cellular Cardiology. volum 148.
Vitenskapelig artikkel

2019

Scrimgeour, Nathan Robert; Wrobel, Aleksandra Zofia; Pinho, Maria; Høydal, Morten. (2019) microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation. American Journal of Physiology - Cell Physiology. volum 318 (1).
Vitenskapelig artikkel
Tari, Atefe R; Norevik, Cecilie Skarstad; Scrimgeour, Nathan Robert; Kobro-Flatmoen, Asgeir; Storm-Mathisen, Jon; Bergersen, Linda Hildegard; Wrann, Christiane D.; Selbæk, Geir; Kivipelto, Miia; Moreira, Jose Bianco Nascimento; Wisløff, Ulrik. (2019) Are the Neuroprotective Effects of Exercise Training Systemically Mediated?. Progress in cardiovascular diseases. volum 62 (2).
Vitenskapelig oversiktsartikkel/review

2017

Pinho, Maria; Scrimgeour, Nathan Robert; Stølen, Tomas; Garten, Karin; Sharma, Animesh; Fonseca, Davi de Miranda; Smith, Godfrey L; Høydal, Morten. (2017) Modeling of cardiac ischaemia and reperfusion injury: a human-based in vitro model using iPS-derived cardiomyocytes. European Heart Journal. volum 38 (1).
Sammendrag/abstract
Scrimgeour, Nathan Robert; Pinho, Maria; Wrobel, Aleksandra Zofia; Høydal, Morten. (2017) MicroRNA-451a regulate expression and activity of matrix metalloproteinases 2 and 9 in human cardiomyocytes. European Heart Journal. volum 38 (1).
Sammendrag/abstract

Tidsskriftspublikasjoner

Aakerøy, Lars; Cheng, Chew W.; Sustova, Pavla; Scrimgeour, Nathan Robert; Wahl, Sissel Gyrid Freim; Steinshamn, Sigurd Loe; Bowen, T Scott; Brønstad, Eivind. (2022) Identification of exercise-regulated genes in mice exposed to cigarette smoke. Physiological Reports. volum 10 (21).
Vitenskapelig artikkel
Huuha, Aleksi Matias; Norevik, Cecilie Skarstad; Moreira, Jose Bianco Nascimento; Kobro-Flatmoen, Asgeir; Scrimgeour, Nathan Robert; Kivipelto, Miia; Van Praag, Henriette; Ziaei, Maryam; Sando, Sigrid Botne; Wisløff, Ulrik; Tari, Atefe R. (2022) Can exercise training teach us how to treat Alzheimer's disease?. Ageing Research Reviews. volum 75.
Vitenskapelig oversiktsartikkel/review
Marwarha, Gurdeep; Røsand, Øystein; Scrimgeour, Nathan Robert; Slagsvold, Katrine Hordnes; Høydal, Morten. (2021) miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner. Biomedicines. volum 10 (1).
Vitenskapelig artikkel
Stølen, Tomas; Høydal, Morten; Ahmed, Muhammad Shakil; Jørgensen, Kari; Garten, Karin; Hortigon-Vinagre, Maria; Zamora, Victor; Scrimgeour, Nathan Robert; Berre, Anne Marie Ormbostad; Nes, Bjarne; Skogvoll, Eirik; Johnsen, Anne Berit; Moreira, Jose Bianco Nascimento; McMullen, Julie R; Attramadal, Håvard; Smith, Godfrey L; Ellingsen, Øyvind; Wisløff, Ulrik. (2020) Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction. Journal of Molecular and Cellular Cardiology. volum 148.
Vitenskapelig artikkel
Scrimgeour, Nathan Robert; Wrobel, Aleksandra Zofia; Pinho, Maria; Høydal, Morten. (2019) microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation. American Journal of Physiology - Cell Physiology. volum 318 (1).
Vitenskapelig artikkel
Tari, Atefe R; Norevik, Cecilie Skarstad; Scrimgeour, Nathan Robert; Kobro-Flatmoen, Asgeir; Storm-Mathisen, Jon; Bergersen, Linda Hildegard; Wrann, Christiane D.; Selbæk, Geir; Kivipelto, Miia; Moreira, Jose Bianco Nascimento; Wisløff, Ulrik. (2019) Are the Neuroprotective Effects of Exercise Training Systemically Mediated?. Progress in cardiovascular diseases. volum 62 (2).
Vitenskapelig oversiktsartikkel/review
Pinho, Maria; Scrimgeour, Nathan Robert; Stølen, Tomas; Garten, Karin; Sharma, Animesh; Fonseca, Davi de Miranda; Smith, Godfrey L; Høydal, Morten. (2017) Modeling of cardiac ischaemia and reperfusion injury: a human-based in vitro model using iPS-derived cardiomyocytes. European Heart Journal. volum 38 (1).
Sammendrag/abstract
Scrimgeour, Nathan Robert; Pinho, Maria; Wrobel, Aleksandra Zofia; Høydal, Morten. (2017) MicroRNA-451a regulate expression and activity of matrix metalloproteinases 2 and 9 in human cardiomyocytes. European Heart Journal. volum 38 (1).
Sammendrag/abstract

Formidling

2017

Poster

Ljones, Kristine; Ness, Henning Ofstad; Scrimgeour, Nathan Robert; Høydal, Morten. (2017) An acute bout of exhaustive endurance exercise induces upregulation of transcripts encoding calcium handling proteins in the right ventricle. 15th Annual CHFR Symposium on Heart Failure ; 2017-09-20 - 2017-09-22.

Språkvelger

Nathan Robert Scrimgeour