TY - JOUR AU - Hjartåker, Anette AU - Engeset, Dagrun AU - Brustad, Magritt AU - Lund, Eiliv PY - 2009/11/05 Y2 - 2024/03/29 TI - Fiskekonsum og kreftrisiko blant norske kvinner - The Norwegian Women and Cancer Study (NOWAC) JF - Norsk Epidemiologi JA - Nor J Epidemiol VL - 10 IS - 1 SE - DO - 10.5324/nje.v10i1.516 UR - https://www.ntnu.no/ojs/index.php/norepid/article/view/516 SP - AB - <strong><span style="font-family: TimesNewRomanPS-BoldMT;"><span style="font-family: TimesNewRomanPS-BoldMT;"><p align="left"> </p></span></span><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">SAMMENDRAG</span></span></strong><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><p align="left">Ved Institutt for samfunnsmedisin, Universitetet i Tromsø, er det over mange år bygget opp en landsdekkende</p><p align="left">prospektiv undersøkelse kalt ’Kvinner, livsstil og helse’/’Kvinner og kreft’. Studien er primært</p><p align="left">designet for å undersøke risikofaktorer for kreft, og i særdeleshet brystkreft. Siden 1991 har drøyt 100 000</p><p align="left">tilfeldig utvalgte kvinner, født 1927-1965, blitt inkludert i studien. Svarprosenten er omlag 60. Deltakerne</p><p align="left">har fylt ut et spørreskjema med noe varierende innhold, men med en del felles kjernespørsmål. Detaljgraden</p><p align="left">når det gjelder kostholdsinformasjon varierer. Av de vel 100 000 kvinnene som deltar har omlag halvparten</p><p align="left">fylt ut et oppfølgingsskjema. Vi er særlig interessert i å studere en eventuell effekt av et høyt fiskekonsum på</p><p align="left">kreftrisiko. Spørsmålene om konsum av fisk og fiskeprodukter er validert mot fettsyresammensetningen i</p><p align="left">serum fosfolipider. Studien inngår i multi-senter prosjektet EPIC – the European Prospective Investigation</p><p align="left">into Cancer and Nutrition. For å kunne sammenlikne kostdata fra de ti deltakerlandene er det utarbeidet en</p><p align="left">intern kalibreringsmetode basert på et strengt standardisert dataprogram for 24-timers kostholdsintervju. I</p><p align="left">Norge vil det bli gjennomført omlag 1800 kostholdsintervju over telefon.</p><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><p align="left">Hjartåker A, Engeset D, Brustad M, Lund E.</p></span></span></span><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><p align="left"> </p></span></span><p align="left"><strong><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">Fish consumption and cancer risk among Norwegian<strong><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><p align="left">women – The Norwegian Women and Cancer Study (NOWAC).</p></span></span></strong></span><strong><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><p align="left"> </p></span></strong></span></strong><em><span style="font-size: x-small; font-family: TimesNewRomanPS-ItalicMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-ItalicMT;">Nor J Epidemiol </span></span></em><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;">2000; </span></span><strong><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">10 </span></span></strong><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;">(1): 63-70.</span></span></p><p align="left"><strong><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;"><span style="font-size: x-small; font-family: TimesNewRomanPS-BoldMT;">ENGLISH SUMMARY</span></span></strong><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><span style="font-size: x-small; font-family: TimesNewRomanPSMT;"><p align="left">The Norwegian Women and Cancer study, NOWAC (in Norwegian: ’Kvinner, livsstil og helse’/’Kvinner og</p><p align="left">kreft’) is a large population-based cohort study primarily designed to examine factors related to cancer, other</p><p align="left">illnesses, and mortality in a prospective manner. In particular, it is designed for investigation of breast</p><p align="left">cancer. Since the establishment in 1991, more than 100 000 Norwegian women born 1927-1965 have been</p><p align="left">included in the cohort. The participants are randomly sampled, and the response rate is about 60%. The</p><p align="left">participants have received a mailed letter of invitation requesting informed consent and a self-instructive</p><p align="left">questionnaire. After sufficient follow-up time, events will be identified by linkage to the Cancer Registry of</p><p align="left">Norway and to the registry of death certificates at Statistics Norway. Dietary data have been collected</p><p align="left">through a food frequency approach. Some 70 000 women have given detailed information about their diet</p><p align="left">during the last year, whereas more scarce dietary data are collected from the rest of the participants. A large</p><p align="left">number of the women have reported their dietary intake twice. Along with information on “usual” diet,</p><p align="left">special attention is given to the consumption of marine foods. Based on earlier findings we want to examine</p><p align="left">a potential protective effect of fish consumption on breast cancer risk. The questions on marine food consumption</p><p align="left">have been validated against serum phospholipid fatty acid composition. In addition to the national</p><p align="left">analyses, NOWAC is part of the large multi-centre study EPIC – the European Prospective Investigation</p><p align="left">into Cancer and Nutrition. To calibrate dietary data across centres a computer based 24-h recall program is</p><p align="left">developed. A sub-sample of about 1800 of the NOWAC participants will be interviewed using this program.</p><p align="left">The interviews are performed by telephone. Building a biological bank is another important part of EPIC,</p><p>and we are planning to collect blood samples via mail for a sub-sample of the Norwegian participants.</p></span></span></p> ER -