Laxmi Bhatta
Om
Research Project
Using Genetics to Investigate the Developmental Origins of Health and Disease
A multidisciplinary research approach on obstructive airway diseases: socio-economical and life course perspectives: Nordic EpiLung project (Norway, Sweden, Finland)
Research Area
Genetic epidemiology
Respiratory Epidemiology
Research Group
Genome-wide association study (GWAS)
Mendelian randomization (MR)
Epidemiology and Medical Statistics
Education
PhD programme in Medicine, Department of Public Health and Nursing, NTNU, Norway (2016 - 2019)
Masters in Public Health (MPH), The Arctic University of Norway (UiT), Norway (2013)
Publikasjoner
2024
-
Backman, Helena;
Bhatta, Laxmi;
Hedman, Linnea;
Brumpton, Ben Michael;
Vähätalo, Iida;
Lassmann-Klee, Paul G..
(2024)
Level of Education Modifies Asthma Mortality in Norway and Sweden. The Nordic EpiLung Study.
Journal of Asthma and Allergy
Vitenskapelig artikkel
-
Moksnes, Marta R.;
Hansen, Ailin F.;
Wolford, Brooke N.;
Thomas, Laurent F.;
Rasheed, Humaira;
Simic, Anica.
(2024)
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans.
Communications Biology
Vitenskapelig artikkel
-
Andersén, Heidi;
Bhatta, Laxmi;
Bashir, Muwada;
Nwaru, Bright;
Langhammer, Arnulf;
Krokstad, Steinar.
(2024)
Is there still a social gradient in respiratory symptoms? A population-based Nordic EpiLung-study.
Respiratory Medicine
Vitenskapelig artikkel
-
Hernandez-Pacheco, Natalia;
Kilanowski, Anna;
Kumar, Ashish;
Curtin, John A.;
Olvera, Núria;
Kress, Sara.
(2024)
Exploring the genetics of airflow limitation in lung function across the lifespan – a polygenic risk score study.
EClinicalMedicine
Vitenskapelig artikkel
-
Sidorenko, Julia;
Couvy-Duchesne, Baptiste;
Kemper, Kathryn E.;
Moen, Gunn-Helen ;
Bhatta, Laxmi;
Åsvold, Bjørn Olav.
(2024)
Genetic architecture reconciles linkage and association studies of complex traits.
Nature Genetics
Vitenskapelig artikkel
2023
-
Honigberg, Michael C.;
Truong, Buu;
Khan, Raiyan R.;
Xiao, Brenda;
Bhatta, Laxmi;
Vy, Ha My T..
(2023)
Polygenic prediction of preeclampsia and gestational hypertension.
Nature Medicine
Vitenskapelig artikkel
-
Arora, Nikhil;
Bhatta, Laxmi;
Skarpsno, Eivind Schjelderup;
Dalen, Håvard;
Åsvold, Bjørn Olav;
Brumpton, Ben Michael.
(2023)
Investigating the causal interplay between sleep traits and risk of acute myocardial infarction: a Mendelian randomization study.
BMC Medicine
Vitenskapelig artikkel
-
Bashir, Muwada Bashir Awad;
Basna, Rani;
Hedman, Linnea;
Backman, Helena;
Ekerljung, Linda;
Andersén, Heidi.
(2023)
Interaction of smoking and social status on the risk of respiratory outcomes in a Swedish adult population: A Nordic Epilung study.
Respiratory Medicine
Vitenskapelig artikkel
-
Wang, Ying;
Namba, Shinichi;
Lopera, Esteban;
Kerminen, Sini;
Tsuo, Kristin;
Läll, Kristi.
(2023)
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts.
Cell Genomics
Vitenskapelig artikkel
2022
-
Zhao, Huiling;
Rasheed, Humaira;
Nøst, Therese Haugdahl;
Cho, Yoonsu;
Liu, Yi;
Bhatta, Laxmi.
(2022)
Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases.
Cell Genomics
Vitenskapelig artikkel
-
Korologou-Linden, Roxanna;
Bhatta, Laxmi;
Brumpton, Ben Michael;
Howe, Laura D.;
Millard, Louise A. C.;
Kolaric, Katarina.
(2022)
The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization.
Nature Communications
Vitenskapelig artikkel
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G..
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics
Vitenskapelig artikkel
-
Moen, Gunn-Helen Øiseth;
Nivard, Michel;
Bhatta, Laxmi;
Warrington, Nicole Maree;
Willer, Cristen;
Åsvold, Bjørn Olav.
(2022)
Using Genomic Structural Equation Modeling to Partition the Genetic Covariance Between Birthweight and Cardiometabolic Risk Factors into Maternal and Offspring Components in the Norwegian HUNT Study.
Behavior Genetics
Vitenskapelig artikkel
2021
-
Bhatta, Laxmi;
Cepelis, Aivaras;
Vikjord, Sigrid Anna Aalberg;
Malmo, Vegard;
Laugsand, Lars Erik;
Dalen, Håvard.
(2021)
Bone mineral density and risk of cardiovascular disease in men and women: the HUNT study.
European Journal of Epidemiology (EJE)
Vitenskapelig artikkel
-
Wang, Geng;
Bhatta, Laxmi;
Moen, Gunn-Helen;
Hwang, Liang-Dar;
Kemp, John P.;
Bond, Tom A..
(2021)
Investigating a Potential Causal Relationship Between Maternal Blood Pressure During Pregnancy and Future Offspring Cardiometabolic Health.
Hypertension
Vitenskapelig artikkel
-
Wilczek, Michael;
Bhatta, Laxmi;
Brumpton, Ben Michael;
Freyschuss, Bo;
Brismar, Torkel B..
(2021)
Screening for women with increased risk of fragility fractures in a general female population using digital X-ray radiogrammetry (DXR).
Maturitas
Vitenskapelig artikkel
2020
-
Bhatta, Laxmi;
Leivseth, Linda;
Mai, Xiao-Mei;
Henriksen, Anne Hildur;
Carslake, David;
Chen, Yue.
(2020)
GOLD classifications, COPD hospitalization, and all-cause mortality in chronic obstructive pulmonary disease: The HUNT study.
The International Journal of Chronic Obstructive Pulmonary Disease
Vitenskapelig artikkel
-
Ferreira, Manuel A R;
Vonk, Judith M.;
Baurecht, Hansjörg;
Marenholz, Ingo;
Tian, Chao;
Hoffman, Joshua D..
(2020)
Age-of-onset information helps identify 76 genetic variants associated with allergic disease.
PLoS Genetics
Vitenskapelig artikkel
-
Bhatta, Laxmi;
Leivseth, Linda;
Mai, Xiao-Mei;
Henriksen, Anne Hildur;
Carslake, David;
Yue, Chen.
(2020)
Spirometric Classifications of COPD Severity as Predictive
Markers for Clinical Outcomes: The HUNT Study.
American Journal of Respiratory and Critical Care Medicine
Vitenskapelig artikkel
2019
-
Bhatta, Laxmi;
Leivseth, Linda;
Carslake, David;
Langhammer, Arnulf;
Mai, Xiao-Mei;
Chen, Yue.
(2019)
Comparison of pre‐ and post‐bronchodilator lung function as predictors of mortality: The HUNT Study.
Respirology (Carlton South. Print)
Vitenskapelig artikkel
-
Vikjord, Sigrid Anna;
Brumpton, Ben Michael;
Mai, Xiao-Mei;
Bhatta, Laxmi;
Vanfleteren, Lowie E.G.W.;
Langhammer, Arnulf.
(2019)
The Association of Bone Mineral Density with Mortality in a COPD Cohort. The HUNT Study, Norway.
COPD: Journal of Chronic Obstructive Pulmonary Disease
Vitenskapelig artikkel
2018
-
Bhatta, Laxmi;
Leivseth, Linda;
Mai, Xiao-Mei;
Chen, Yue;
Henriksen, Anne Hildur;
Langhammer, Arnulf.
(2018)
Prevalence and trend of COPD from 1995–1997 to 2006–2008: The HUNT study, Norway.
Respiratory Medicine
Vitenskapelig artikkel
2013
-
Bhatta, Laxmi;
Klouman, Elise;
Deuba, Keshab;
Shrestha, Rachana;
Karki, Deepak Kumar;
Ekström, Anna Mia.
(2013)
Survival on antiretroviral treatment among adult HIV-infected patients in Nepal: a retrospective cohort study in far-western Region, 2006–2011.
BMC Infectious Diseases
Vitenskapelig artikkel
Tidsskriftspublikasjoner
-
Backman, Helena;
Bhatta, Laxmi;
Hedman, Linnea;
Brumpton, Ben Michael;
Vähätalo, Iida;
Lassmann-Klee, Paul G..
(2024)
Level of Education Modifies Asthma Mortality in Norway and Sweden. The Nordic EpiLung Study.
Journal of Asthma and Allergy
Vitenskapelig artikkel
-
Moksnes, Marta R.;
Hansen, Ailin F.;
Wolford, Brooke N.;
Thomas, Laurent F.;
Rasheed, Humaira;
Simic, Anica.
(2024)
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans.
Communications Biology
Vitenskapelig artikkel
-
Andersén, Heidi;
Bhatta, Laxmi;
Bashir, Muwada;
Nwaru, Bright;
Langhammer, Arnulf;
Krokstad, Steinar.
(2024)
Is there still a social gradient in respiratory symptoms? A population-based Nordic EpiLung-study.
Respiratory Medicine
Vitenskapelig artikkel
-
Hernandez-Pacheco, Natalia;
Kilanowski, Anna;
Kumar, Ashish;
Curtin, John A.;
Olvera, Núria;
Kress, Sara.
(2024)
Exploring the genetics of airflow limitation in lung function across the lifespan – a polygenic risk score study.
EClinicalMedicine
Vitenskapelig artikkel
-
Sidorenko, Julia;
Couvy-Duchesne, Baptiste;
Kemper, Kathryn E.;
Moen, Gunn-Helen ;
Bhatta, Laxmi;
Åsvold, Bjørn Olav.
(2024)
Genetic architecture reconciles linkage and association studies of complex traits.
Nature Genetics
Vitenskapelig artikkel
-
Honigberg, Michael C.;
Truong, Buu;
Khan, Raiyan R.;
Xiao, Brenda;
Bhatta, Laxmi;
Vy, Ha My T..
(2023)
Polygenic prediction of preeclampsia and gestational hypertension.
Nature Medicine
Vitenskapelig artikkel
-
Arora, Nikhil;
Bhatta, Laxmi;
Skarpsno, Eivind Schjelderup;
Dalen, Håvard;
Åsvold, Bjørn Olav;
Brumpton, Ben Michael.
(2023)
Investigating the causal interplay between sleep traits and risk of acute myocardial infarction: a Mendelian randomization study.
BMC Medicine
Vitenskapelig artikkel
-
Bashir, Muwada Bashir Awad;
Basna, Rani;
Hedman, Linnea;
Backman, Helena;
Ekerljung, Linda;
Andersén, Heidi.
(2023)
Interaction of smoking and social status on the risk of respiratory outcomes in a Swedish adult population: A Nordic Epilung study.
Respiratory Medicine
Vitenskapelig artikkel
-
Wang, Ying;
Namba, Shinichi;
Lopera, Esteban;
Kerminen, Sini;
Tsuo, Kristin;
Läll, Kristi.
(2023)
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts.
Cell Genomics
Vitenskapelig artikkel
-
Zhao, Huiling;
Rasheed, Humaira;
Nøst, Therese Haugdahl;
Cho, Yoonsu;
Liu, Yi;
Bhatta, Laxmi.
(2022)
Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases.
Cell Genomics
Vitenskapelig artikkel
-
Korologou-Linden, Roxanna;
Bhatta, Laxmi;
Brumpton, Ben Michael;
Howe, Laura D.;
Millard, Louise A. C.;
Kolaric, Katarina.
(2022)
The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization.
Nature Communications
Vitenskapelig artikkel
-
Brumpton, Ben Michael;
Graham, Sarah;
Surakka, Ida;
Skogholt, Anne Heidi;
Løset, Mari;
Fritsche, Lars G..
(2022)
The HUNT study: A population-based cohort for genetic research.
Cell Genomics
Vitenskapelig artikkel
-
Moen, Gunn-Helen Øiseth;
Nivard, Michel;
Bhatta, Laxmi;
Warrington, Nicole Maree;
Willer, Cristen;
Åsvold, Bjørn Olav.
(2022)
Using Genomic Structural Equation Modeling to Partition the Genetic Covariance Between Birthweight and Cardiometabolic Risk Factors into Maternal and Offspring Components in the Norwegian HUNT Study.
Behavior Genetics
Vitenskapelig artikkel
-
Bhatta, Laxmi;
Cepelis, Aivaras;
Vikjord, Sigrid Anna Aalberg;
Malmo, Vegard;
Laugsand, Lars Erik;
Dalen, Håvard.
(2021)
Bone mineral density and risk of cardiovascular disease in men and women: the HUNT study.
European Journal of Epidemiology (EJE)
Vitenskapelig artikkel
-
Wang, Geng;
Bhatta, Laxmi;
Moen, Gunn-Helen;
Hwang, Liang-Dar;
Kemp, John P.;
Bond, Tom A..
(2021)
Investigating a Potential Causal Relationship Between Maternal Blood Pressure During Pregnancy and Future Offspring Cardiometabolic Health.
Hypertension
Vitenskapelig artikkel
-
Wilczek, Michael;
Bhatta, Laxmi;
Brumpton, Ben Michael;
Freyschuss, Bo;
Brismar, Torkel B..
(2021)
Screening for women with increased risk of fragility fractures in a general female population using digital X-ray radiogrammetry (DXR).
Maturitas
Vitenskapelig artikkel
-
Bhatta, Laxmi;
Leivseth, Linda;
Mai, Xiao-Mei;
Henriksen, Anne Hildur;
Carslake, David;
Chen, Yue.
(2020)
GOLD classifications, COPD hospitalization, and all-cause mortality in chronic obstructive pulmonary disease: The HUNT study.
The International Journal of Chronic Obstructive Pulmonary Disease
Vitenskapelig artikkel
-
Ferreira, Manuel A R;
Vonk, Judith M.;
Baurecht, Hansjörg;
Marenholz, Ingo;
Tian, Chao;
Hoffman, Joshua D..
(2020)
Age-of-onset information helps identify 76 genetic variants associated with allergic disease.
PLoS Genetics
Vitenskapelig artikkel
-
Bhatta, Laxmi;
Leivseth, Linda;
Mai, Xiao-Mei;
Henriksen, Anne Hildur;
Carslake, David;
Yue, Chen.
(2020)
Spirometric Classifications of COPD Severity as Predictive
Markers for Clinical Outcomes: The HUNT Study.
American Journal of Respiratory and Critical Care Medicine
Vitenskapelig artikkel
-
Bhatta, Laxmi;
Leivseth, Linda;
Carslake, David;
Langhammer, Arnulf;
Mai, Xiao-Mei;
Chen, Yue.
(2019)
Comparison of pre‐ and post‐bronchodilator lung function as predictors of mortality: The HUNT Study.
Respirology (Carlton South. Print)
Vitenskapelig artikkel
-
Vikjord, Sigrid Anna;
Brumpton, Ben Michael;
Mai, Xiao-Mei;
Bhatta, Laxmi;
Vanfleteren, Lowie E.G.W.;
Langhammer, Arnulf.
(2019)
The Association of Bone Mineral Density with Mortality in a COPD Cohort. The HUNT Study, Norway.
COPD: Journal of Chronic Obstructive Pulmonary Disease
Vitenskapelig artikkel
-
Bhatta, Laxmi;
Leivseth, Linda;
Mai, Xiao-Mei;
Chen, Yue;
Henriksen, Anne Hildur;
Langhammer, Arnulf.
(2018)
Prevalence and trend of COPD from 1995–1997 to 2006–2008: The HUNT study, Norway.
Respiratory Medicine
Vitenskapelig artikkel
-
Bhatta, Laxmi;
Klouman, Elise;
Deuba, Keshab;
Shrestha, Rachana;
Karki, Deepak Kumar;
Ekström, Anna Mia.
(2013)
Survival on antiretroviral treatment among adult HIV-infected patients in Nepal: a retrospective cohort study in far-western Region, 2006–2011.
BMC Infectious Diseases
Vitenskapelig artikkel
Formidling
2024
-
Vitenskapelig foredragVinueza Veloz, Maria Fernanda; Næss, Øyvind Erik; Bhatta, Laxmi; Brumpton, Ben Michael; Jones, Paul Remy. (2024) Estimating maternal and paternal effects of educational attainment on offspring. University of Bristol 6th Mendelian randomization conference, 2024 , Bristol Storbritannia 2024-06-19 - 2024-06-21
2019
-
PosterBackman, Helena; Bhatta, Laxmi; Hedman, Linnea; Brumpton, Ben Michael; Vähätalo, Iida; Lassman-Klee, Paul G.. (2019) Asthma is still a risk factor for mortality in Sweden and Norway – the Nordic EpiLung Study. European Respiratory Society (ERS) Congress 2019 2019-09-28 -
-
PosterVikjord, Sigrid Anna; Brumpton, Ben Michael; Mai, Xiao-Mei; Bhatta, Laxmi; Vanfleteren, Lowie E.G.W.; Langhammer, Arnulf. (2019) The association of anxiety and depression with mortality, symptom burden and health care utilization in a COPD cohort. The HUNT Study, Norway. European Respiratory Society (ERS) Congress 2019 2019-09-28 -
2017
-
PosterBhatta, Laxmi; Leivseth, Linda; Mai, Xiao-Mei; Chen, Yue; Henriksen, Anne Hildur; Langhammer, Arnulf. (2017) The prevalence of Chronic Obstructive Pulmonary Disease (COPD) in 1995-97 and 2006-08: The HUNT study, Norway. European Respiratory Society (ERS) Congress 2017 2017-09-09 - 2017-09-13