Neonatal alloimmun trombocytopenisk purpura (NAITP)
DOI:
https://doi.org/10.5324/nje.v7i1.360Abstract
SAMMENDRAG
Neonatal alloimmun trombocytopenisk purpura (NAITP) opptrer før eller like etter fødselen, og er
forårsaket av maternell alloimmunisering mot paternelle (føtale) antigener som ikke er tilstede på morens
trombocytter. Incidensen er 1 pr. 2000/3000 nyfødte. Det finnes ikke noe screening-opplegg for å avsløre
mødre som kommer til å føde barn med NAITP. Derfor fins det heller ikke noe man kan gjøre før en
kvinne føder sitt første barn med tilstanden. I påfølgende svangerskap kan moren følges, og man kan
planlegge tiltak for å redusere risikoen for skade på barnet.
Skogen B.
Neonatal alloimmune thrombocytopenic purpura. Nor J Epidemiol 1997; 7 (1): 69-72.
ENGLISH SUMMARY
Neonatal alloimmune thrombocytopenic purpura (NAITP) manifests itself before or shortly after birth
and is caused by maternal alloimmunization to a paternal (fetal) antigen not present on the mother’s
platelets. The incidence of the condition in the fetus and neonate is 1 in 2000/3000 live births. There are
no screening programs for detecting mothers at risk of delivering infants affected with NAITP. Therefore,
no antenatal management is possible in first pregnancies. In subsequent pregnancies there is an opportunity
to detect affected fetuses and plan perinatal therapy.
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