Multiple Myeloma

Multiple myeloma is a cancer due to clonal expansion of malignant plasma (antibody-producing) cells, usually confined to the bone marrow. Key questions regarding the basic biology of multiple myeloma are why do myeloma cells survive and proliferate within the bone marrow, and how do the presence of myeloma cells in bone marrow cause the characteristic bone degradation usually seen in multiple myeloma. The group has a translational approach to understanding and treating multiple myeloma, studying these questions in primary myeloma cells, in myeloma cell lines and in animal models of multiple myeloma. The group is also running clinical studies exploring new treatments for multiple myeloma (e.g. thalidomide). The group consists of about 15 people, approx. equal numbers of postdocs, PhD-students and medical students (“forskerlinjestudenter”) at any time.