Bakgrunn og aktiviteter

Forskning:

 

Se hjemmeside: http://www.ntnu.edu/chemistry/research/organic/bioorganic-chemistry

 

Undervisning:

Organisk syntese I-TKJ4150

TKJ4130

KJ8107

TKJ4155

 

 

Vitenskapelig, faglig og kunstnerisk arbeid

Viser et utvalg av aktivitet. Se alle publikasjoner i databasen

2017

2016

2015

2014

2013

2012

2011

2010

2009

2008

2006

  • Hoff, Bård Helge; Anthonsen, Thorleif; Fuglseth, Erik. (2006) New chiral building blocks from acetovanillone using lipase A and B from Candida antarctica. Tetrahedron: asymmetry. vol. 17 (8).

2004

  • Moen, A. R.; Hoff, B. H.; Hansen, Lars Kr; Anthonsen, T.; Jacobsen, E. E.. (2004) Absolute configurations of monoesters produced by enzyme catalyzed hydrolysis of diethyl 3-hydroxyglutarate. Tetrahedron: asymmetry. vol. 15.

2003

  • Jacobsen, Elisabeth Egholm; Hoff, Bård Helge; Moen, Anders Riise; Anthonsen, Thorleif. (2003) Enantioselective enzymatic preparation of chiral glutaric monocarboxylic acids and amides. Journal of Molecular Catalysis B: Enzymatic. vol. 21.

2002

  • Sundby, Eirik; Anthonsen, Thorleif; Andersen, Morten Myhre; Hoff, Bård Helge. (2002) Lipase catalysed resolution and microbial reduction for obtaining enantiopure 1-(2-thienyl)alkanols. ARKIVOC.

2001

  • Liu, Hui-Ling; Hoff, Bård Helge; Berg, Tom Christian; Anthonsen, Thorleif. (2001) Synthesis of the anti-stroke drug Lubeluzole and its enantiomer. Lipase catalyzed resolution of chiral building block. Chirality. vol. 13.

2000

  • Egholm Jacobsen, Elisabeth; Hoff, Bård Helge; Anthonsen, Thorleif. (2000) Enantiopure derivatives of 1,2-alkanediols. Substrate requirements for lipase B from Candida antarctica. Chirality. vol. 12.
  • Hoff, Bård; Ljones, Liv; Rønstad, Anja; Anthonsen, Thorleif. (2000) Influence of Substituents on Enantiomeric Ratio in Transesterification of Racemic C-3 Synthons using Lipase B from Candida antarctica. Journal of Molecular Catalysis B: Enzymatic. vol. 8.
  • Jacobsen, Elisabeth Egholm; Hoff, Bård Helge; Anthonsen, Thorleif. (2000) Enantiopure derivatives of 1,2-alkanediols: Substrate requirements of lipase B from Candida antarctica. Chirality. vol. 12.
  • Liu, Hui Ling; Hoff, Bård Helge; Anthonsen, Thorleif. (2000) Chemoenzymatic synthesis of the antidepressant Duloxetine and its enantiomer. Chirality. vol. 12.
  • Liu, Hui-Ling; Hoff, Bård Helge; Anthonsen, Thorleif. (2000) Chemo-enzymatic synthesis of both enantiomers of the non-tricyclic antidepressants Fluoxetine, Nisoxetine and Tomoxetine. Journal of the Chemical Society. Perkin transactions 1.

1999

  • Anthonsen, Thorleif; Hoff, Bård Helge. (1999) Gas Chromatographic enantiomer separation of C-3 and C-4 synthons. Combination with enzymatic resolution to determine absolute configuration. Chirality. vol. 11.
  • Anthonsen, Thorleif; Hoff, Bård Helge; Hofsløkken, Nini; Skattebøl, Lars; Sundby, Eirik. (1999) Synthesis of 1,3-dithianes and 1,3-dithiolanes. Baker´s yeast reduction and lipase-catalyzed resolution for synthesis of enantiopure derivatives. Acta Chemica Scandinavica. vol. 53.
  • Anthonsen, Thorleif; Hoff, Bård Helge; Liu, Hui-Ling; Sundby, Eirik. (1999) Enantiopure chiral building blocks by biocatalysis. Metal and bio-promoted selective organic transformations. COST D12 Workshop . [Mangler data]; Sassari-Porto Conte, Italia, Oktober 1999.
  • Berg, Tom Christian; Hoff, Bård Helge; Anthonsen, Thorleif. (1999) Chemo-enzymatic synthesis of the drug Lubeluzole. 7. Nordic Conference on Biocatalysis in Organic Chemistry . [Mangler data]; Teveltunet fjellstue, Norway. 8.-11. April 1999.
  • Hoff, Bård Helge; Anthonsen, Thorleif. (1999) Lipase catalyzed resolution of esters of 4-chloro-3-hydroxy butanoic acid. Effect of alkoxy group and solvent on enantiomeric ratio. 7. Nordic Conference on Biocatalysis in Organic Chemistry . [Mangler data]; Teveltunet fjellstue, 8.-11. april 1999.
  • Hoff, Bård Helge; Anthonsen, Thorleif. (1999) Lipase catalyzed resolution of esters of 4-chloro-3-hydroxybutanoic acid. Effect of alkoxy group and solvent on enantiomeric ratio. Tetrahedron: asymmetry. vol. 10.
  • Jacobsen, Elisabeth Egholm; Hoff, Bård Helge; Anthonsen, Thorleif. (1999) Significance of substrate structure, acyl donor and water activity for E in resolutions of secondary alcohols catalysed by CALB. 7. Nordic Conference on Biocatalysis in Organic Chemistry . [Mangler data]; Teveltunet fjellstue, 8- 11. april 1999. 1999-04-17 - 1999-04-20.
  • Anthonsen, Thorleif; Hoff, Bård H.; Hofsløkken, Nini Unn; Skattebøl, Lars; Sundby, Eirik. (1999) Synthesis of 1,3-Dithianes and 1,3-Dithiolanes. Baker's Yeast reduction and Lipase-Catalyzed resolution for synthesis of Enantiopure derivatives. Acta Chemica Scandinavica. vol. 53.

1998

  • Hoff, Bård; Anthonsen, Thorleif. (1998) Resolution of Derivatives of 1,2-Propanediol with Lipase B from Candida antarctica. Effect of Substrate Structure, Medium, Water Activity and Acyl on Enantiomeric Ratio. Chemistry and Physics of Lipids. vol. 93 (xx).

1997

  • Hoff, Bård; Anthonsen, Henrik; Anthonsen, Thorleif. (1997) Lipase catalysed resolution in organic solvent : the enantiomer ratio strongly depends on the alkyl part of the acyl donor in transesterification with lipase B from Candida antarctica. Organisk kjemisk vintermøte . [Mangler data]; Fefor.

1996

  • Anthonsen, H.W.; Hoff, B.H.; Anthonsen, Thorleif. (1996) Calculation of enantiomer ratio and equilibrium constants in biocatalytic ping-pong bi-bi resolutions. Tetrahedron: asymmetry. vol. 7.
  • Anthonsen, H.W.; Hoff, B.H.; Anthonsen, Thorleif. (1996) Calculation of enantiomer ratio and equilibrium constants in biocatalytic resolutions : resolution of derivatives of 1,2-propanediol. 11. Organisk kjemisk vintermøte . [Mangler data]; [Mangler data].
  • Hoff, B.H.; Anthonsen, H.W.; Anthonsen, Thorleif. (1996) The enantiomer ratio strongly depends on the alkyl part of the acyl donor in transesterification with lipase B from Candida antarctica. Tetrahedron: asymmetry. vol. 7.
  • Hoff, B.H.; Waagen, V.; Anthonsen, Thorleif. (1996) Resolution of 1-phenoxy-, 1-phenylmethoxy- and 1-(2-phenylethoxy)-2-propanol and their butanoates by hydrolysis with lipase B from Candida antarctica. Tetrahedron: asymmetry. vol. 7.

1995

  • Anthonsen, Henrik Walbye; Hoff, Bård Helge; Anthonsen, Thorleif. (1995) A simple method for calculating enantiomer ratio and equilibrium constants in biocatalytic resolutions. Tetrahedron: asymmetry. vol. 6.